Result of FASTA (ccds) for
pFN21AE6757
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE6757, 533 aa
1>>>pF1KE6757 533 - 533 aa - 533 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 8.6372+/-0.00125; mu= 4.5648+/- 0.074
mean_var=298.7557+/-58.726, 0's: 0 Z-trim(109.2): 53 B-trim: 166 in 1/51
Lambda= 0.074202
statistics sampled from 10675 (10704) to 10675 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.674), E-opt: 0.2 (0.329), width: 16
Scan time: 2.290
The best scores are: opt bits E(32554)
CCDS73265.1 USH1C gene_id:10083|Hs108|chr11 ( 533) 3516 390.7 2.3e-108
CCDS31438.1 USH1C gene_id:10083|Hs108|chr11 ( 552) 1881 215.6 1.2e-55
CCDS7825.1 USH1C gene_id:10083|Hs108|chr11 ( 899) 1881 215.9 1.6e-55
>>CCDS73265.1 USH1C gene_id:10083|Hs108|chr11 (533 aa)
initn: 3516 init1: 3516 opt: 3516 Z-score: 2058.8 bits: 390.7 E(32554): 2.3e-108
Smith-Waterman score: 3516; 99.8% identity (100.0% similar) in 533 aa overlap (1-533:1-533)
10 20 30 40 50 60
pF1KE6 MDRKVAREFRHKVDFLIENDAEKDYLYDVLRMYHQTMDVAVLVGDLKLVINEPSRLPLFD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS73 MDRKVAREFRHKVDFLIENDAEKDYLYDVLRMYHQTMDVAVLVGDLKLVINEPSRLPLFD
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 AIRPLIPLKHQVEYDQLTPRRSRKLKEVRLDRLHPEGLGLSVRGGLEFGCGLFISHLIKG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS73 AIRPLIPLKHQVEYDQLTPRRSRKLKEVRLDRLHPEGLGLSVRGGLEFGCGLFISHLIKG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 GQADSVGLQVGDEIVRINGYSISSCTHEEVINLIRTKKTVSIKVRHIGLIPVKSSPDEPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS73 GQADSVGLQVGDEIVRINGYSISSCTHEEVINLIRTKKTVSIKVRHIGLIPVKSSPDEPL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE6 TWQYVDQFVSESGGVRGSLGSPGNRENKEKKVFISLVGSRGLGCSISSGPIQKPGIFISH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS73 TWQYVDQFVSESGGVRGSLGSPGNRENKEKKVFISLVGSRGLGCSISSGPIQKPGIFISH
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE6 VKPGSLSAEVGLEIGDQIVEVNGVDFSNLDHKEGRELFMTDRERLAEARQRELQRQELLM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS73 VKPGSLSAEVGLEIGDQIVEVNGVDFSNLDHKEGRELFMTDRERLAEARQRELQRQELLM
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE6 QKRLAMESNKILQEQQEMERQRRKEIAQKAAEENERYRKEMEQIVEEEEKFKKQWEEDWG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS73 QKRLAMESNKILQEQQEMERQRRKEIAQKAAEENERYRKEMEQIVEEEEKFKKQWEEDWG
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE6 SKEQLLLPKTITAEVHPVPLRKPKYDQGVEPELEPADDLDGGTEEQGEQDFRKYEEGFDP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS73 SKEQLLLPKTITAEVHPVPLRKPKYDQGVEPELEPADDLDGGTEEQGEQDFRKYEEGFDP
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE6 YSMFTPEQIMGKDVRLLRIKKEGSLDLALEGGVDSPIGKVVVSAVYERGAAERHGGIVKG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS73 YSMFTPEQIMGKDVRLLRIKKEGSLDLALEGGVDSPIGKVVVSAVYERGAAERHGGIVKG
430 440 450 460 470 480
490 500 510 520 530
pF1KE6 DEIMAINGKIVTDYTLAEADAALQKAWNQGGDWIDLVVAVCPPKEYDDELTFF
:::::::::::::::::::.:::::::::::::::::::::::::::::::::
CCDS73 DEIMAINGKIVTDYTLAEAEAALQKAWNQGGDWIDLVVAVCPPKEYDDELTFF
490 500 510 520 530
>>CCDS31438.1 USH1C gene_id:10083|Hs108|chr11 (552 aa)
initn: 1834 init1: 1834 opt: 1881 Z-score: 1112.7 bits: 215.6 E(32554): 1.2e-55
Smith-Waterman score: 3468; 96.4% identity (96.6% similar) in 552 aa overlap (1-533:1-552)
10 20 30 40 50 60
pF1KE6 MDRKVAREFRHKVDFLIENDAEKDYLYDVLRMYHQTMDVAVLVGDLKLVINEPSRLPLFD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS31 MDRKVAREFRHKVDFLIENDAEKDYLYDVLRMYHQTMDVAVLVGDLKLVINEPSRLPLFD
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 AIRPLIPLKHQVEYDQLTPRRSRKLKEVRLDRLHPEGLGLSVRGGLEFGCGLFISHLIKG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS31 AIRPLIPLKHQVEYDQLTPRRSRKLKEVRLDRLHPEGLGLSVRGGLEFGCGLFISHLIKG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 GQADSVGLQVGDEIVRINGYSISSCTHEEVINLIRTKKTVSIKVRHIGLIPVKSSPDEPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS31 GQADSVGLQVGDEIVRINGYSISSCTHEEVINLIRTKKTVSIKVRHIGLIPVKSSPDEPL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE6 TWQYVDQFVSESGGVRGSLGSPGNRENKEKKVFISLVGSRGLGCSISSGPIQKPGIFISH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS31 TWQYVDQFVSESGGVRGSLGSPGNRENKEKKVFISLVGSRGLGCSISSGPIQKPGIFISH
190 200 210 220 230 240
250 260 270 280
pF1KE6 VKPGSLSAEVGLEIGDQIVEVNGVDFSNLDHKE-------------------GRELFMTD
::::::::::::::::::::::::::::::::: ::::::::
CCDS31 VKPGSLSAEVGLEIGDQIVEVNGVDFSNLDHKEAVNVLKSSRSLTISIVAAAGRELFMTD
250 260 270 280 290 300
290 300 310 320 330 340
pF1KE6 RERLAEARQRELQRQELLMQKRLAMESNKILQEQQEMERQRRKEIAQKAAEENERYRKEM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS31 RERLAEARQRELQRQELLMQKRLAMESNKILQEQQEMERQRRKEIAQKAAEENERYRKEM
310 320 330 340 350 360
350 360 370 380 390 400
pF1KE6 EQIVEEEEKFKKQWEEDWGSKEQLLLPKTITAEVHPVPLRKPKYDQGVEPELEPADDLDG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS31 EQIVEEEEKFKKQWEEDWGSKEQLLLPKTITAEVHPVPLRKPKYDQGVEPELEPADDLDG
370 380 390 400 410 420
410 420 430 440 450 460
pF1KE6 GTEEQGEQDFRKYEEGFDPYSMFTPEQIMGKDVRLLRIKKEGSLDLALEGGVDSPIGKVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS31 GTEEQGEQDFRKYEEGFDPYSMFTPEQIMGKDVRLLRIKKEGSLDLALEGGVDSPIGKVV
430 440 450 460 470 480
470 480 490 500 510 520
pF1KE6 VSAVYERGAAERHGGIVKGDEIMAINGKIVTDYTLAEADAALQKAWNQGGDWIDLVVAVC
::::::::::::::::::::::::::::::::::::::.:::::::::::::::::::::
CCDS31 VSAVYERGAAERHGGIVKGDEIMAINGKIVTDYTLAEAEAALQKAWNQGGDWIDLVVAVC
490 500 510 520 530 540
530
pF1KE6 PPKEYDDELTFF
::::::::::::
CCDS31 PPKEYDDELTFF
550
>>CCDS7825.1 USH1C gene_id:10083|Hs108|chr11 (899 aa)
initn: 2629 init1: 1834 opt: 1881 Z-score: 1110.3 bits: 215.9 E(32554): 1.6e-55
Smith-Waterman score: 2481; 84.6% identity (88.5% similar) in 469 aa overlap (1-441:1-467)
10 20 30 40 50 60
pF1KE6 MDRKVAREFRHKVDFLIENDAEKDYLYDVLRMYHQTMDVAVLVGDLKLVINEPSRLPLFD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS78 MDRKVAREFRHKVDFLIENDAEKDYLYDVLRMYHQTMDVAVLVGDLKLVINEPSRLPLFD
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 AIRPLIPLKHQVEYDQLTPRRSRKLKEVRLDRLHPEGLGLSVRGGLEFGCGLFISHLIKG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS78 AIRPLIPLKHQVEYDQLTPRRSRKLKEVRLDRLHPEGLGLSVRGGLEFGCGLFISHLIKG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 GQADSVGLQVGDEIVRINGYSISSCTHEEVINLIRTKKTVSIKVRHIGLIPVKSSPDEPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS78 GQADSVGLQVGDEIVRINGYSISSCTHEEVINLIRTKKTVSIKVRHIGLIPVKSSPDEPL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE6 TWQYVDQFVSESGGVRGSLGSPGNRENKEKKVFISLVGSRGLGCSISSGPIQKPGIFISH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS78 TWQYVDQFVSESGGVRGSLGSPGNRENKEKKVFISLVGSRGLGCSISSGPIQKPGIFISH
190 200 210 220 230 240
250 260 270 280
pF1KE6 VKPGSLSAEVGLEIGDQIVEVNGVDFSNLDHKE-------------------GRELFMTD
::::::::::::::::::::::::::::::::: ::::::::
CCDS78 VKPGSLSAEVGLEIGDQIVEVNGVDFSNLDHKEAVNVLKSSRSLTISIVAAAGRELFMTD
250 260 270 280 290 300
290 300 310 320 330 340
pF1KE6 RERLAEARQRELQRQELLMQKRLAMESNKILQEQQEMERQRRKEIAQKAAEENERYRKEM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS78 RERLAEARQRELQRQELLMQKRLAMESNKILQEQQEMERQRRKEIAQKAAEENERYRKEM
310 320 330 340 350 360
350 360 370 380 390
pF1KE6 EQIVEEEEKFKKQWEEDWGSKEQLLLPKTITAEVHPVPLRKPK-------YDQGVEPELE
::::::::::::::::::::::::::::::::::::::::::: :: : : ..
CCDS78 EQIVEEEEKFKKQWEEDWGSKEQLLLPKTITAEVHPVPLRKPKSFGWFYRYD-GKFPTIR
370 380 390 400 410
400 410 420 430 440 450
pF1KE6 PADDLDGGTEEQGE-QDFRKYEEGFD-PYSMFTPEQIMGKDVRLLRIKKEGSLDLALEGG
: . : ::.:: .. .. ... .. : . . :.:..
CCDS78 KKGK-DKKKAKYGSLQDLRKNKKELEFEQKLYKEKEEMLEKEKQLKINRLAQEVSETERE
420 430 440 450 460 470
460 470 480 490 500 510
pF1KE6 VDSPIGKVVVSAVYERGAAERHGGIVKGDEIMAINGKIVTDYTLAEADAALQKAWNQGGD
CCDS78 DLEESEKIQYWVERLCQTRLEQISSADNEISEMTTGPPPPPPSVSPLAPPLRRFAGGLHL
480 490 500 510 520 530
>--
initn: 851 init1: 809 opt: 814 Z-score: 493.0 bits: 101.7 E(32554): 3.9e-21
Smith-Waterman score: 814; 85.8% identity (90.5% similar) in 148 aa overlap (385-530:702-849)
360 370 380 390 400 410
pF1KE6 WEEDWGSKEQLLLPKTITAEVHPVPLRKPKYDQGVEPELEPADDLDGGTEEQG--EQDFR
: .:. :. : . : . : .::::
CCDS78 TFCPSPQPPRGPGVSTISKPVMVHQEPNFIYRPAVKSEVLPQEMLKRMVVYQTAFRQDFR
680 690 700 710 720 730
420 430 440 450 460 470
pF1KE6 KYEEGFDPYSMFTPEQIMGKDVRLLRIKKEGSLDLALEGGVDSPIGKVVVSAVYERGAAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS78 KYEEGFDPYSMFTPEQIMGKDVRLLRIKKEGSLDLALEGGVDSPIGKVVVSAVYERGAAE
740 750 760 770 780 790
480 490 500 510 520 530
pF1KE6 RHGGIVKGDEIMAINGKIVTDYTLAEADAALQKAWNQGGDWIDLVVAVCPPKEYDDELTF
:::::::::::::::::::::::::::.::::::::::::::::::::::::::::::
CCDS78 RHGGIVKGDEIMAINGKIVTDYTLAEAEAALQKAWNQGGDWIDLVVAVCPPKEYDDELAS
800 810 820 830 840 850
pF1KE6 F
CCDS78 LPSSVAESPQPVRKLLEDRAAVHRHGFLLQLEPTDLLLKSKRGNQIHR
860 870 880 890
533 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Nov 8 16:05:18 2016 done: Tue Nov 8 16:05:18 2016
Total Scan time: 2.290 Total Display time: 0.030
Function used was FASTA [36.3.4 Apr, 2011]