Result of FASTA (omim) for
pFN21AE6752
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE6752, 625 aa
1>>>pF1KE6752 625 - 625 aa - 625 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 4.7635+/-0.000418; mu= 22.2637+/- 0.026
mean_var=60.0756+/-12.075, 0's: 0 Z-trim(109.7): 9 B-trim: 212 in 1/52
Lambda= 0.165472
statistics sampled from 17884 (17891) to 17884 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.572), E-opt: 0.2 (0.21), width: 16
Scan time: 9.850
The best scores are: opt bits E(85289)
NP_001477 (OMIM: 600842,613463) glucokinase regula ( 625) 4042 974.0 0
XP_016859285 (OMIM: 600842,613463) PREDICTED: gluc ( 435) 2827 683.8 3.3e-196
XP_016859286 (OMIM: 600842,613463) PREDICTED: gluc ( 435) 2827 683.8 3.3e-196
XP_011531065 (OMIM: 600842,613463) PREDICTED: gluc ( 333) 2071 503.2 5.8e-142
>>NP_001477 (OMIM: 600842,613463) glucokinase regulatory (625 aa)
initn: 4042 init1: 4042 opt: 4042 Z-score: 5208.8 bits: 974.0 E(85289): 0
Smith-Waterman score: 4042; 99.8% identity (99.8% similar) in 625 aa overlap (1-625:1-625)
10 20 30 40 50 60
pF1KE6 MPGTKRFQHVIETPEPGKWELSGYEAAVPITEKSNPLTQDLDKADAENIVRLLGQCDAEI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MPGTKRFQHVIETPEPGKWELSGYEAAVPITEKSNPLTQDLDKADAENIVRLLGQCDAEI
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 FQEEGQALSTYQRLYSESILTTMVQVAGKVQEVLKEPDGGLVVLSGGGTSGRMAFLMSVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FQEEGQALSTYQRLYSESILTTMVQVAGKVQEVLKEPDGGLVVLSGGGTSGRMAFLMSVS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 FNQLMKGLGQKPLYTYLIAGGDRSVVASREGTEDSALHGIEELKKVAAGKKRVIVIGISV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FNQLMKGLGQKPLYTYLIAGGDRSVVASREGTEDSALHGIEELKKVAAGKKRVIVIGISV
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE6 GLSAPFVAGQMDCCMNNTAVFLPVLVGFNPVSMARNDPIEDWSSTFRQVAERMQKMQEKQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GLSAPFVAGQMDCCMNNTAVFLPVLVGFNPVSMARNDPIEDWSSTFRQVAERMQKMQEKQ
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE6 KAFVLNPAIGPEGLSGSSRMKGGSATKILLETLLLAAHKTVDQGIAASQRCLLEILRTFE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KAFVLNPAIGPEGLSGSSRMKGGSATKILLETLLLAAHKTVDQGIAASQRCLLEILRTFE
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE6 RAHQVTYSQSPKIATLMKSVSTSLEKKGHVYLVGWQTLGIIAIMDGVECIHTFGADFRDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RAHQVTYSQSPKIATLMKSVSTSLEKKGHVYLVGWQTLGIIAIMDGVECIHTFGADFRDV
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE6 RGFLIGDHSDMFNQKAELTNQGPQFTFSQEDFLTSILPSLTEIDTVVFIFTLDDNLTEVQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RGFLIGDHSDMFNQKAELTNQGPQFTFSQEDFLTSILPSLTEIDTVVFIFTLDDNLTEVQ
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE6 TIVEQVKEKTNHIQALAHSTVGQTLPIPLKKLFPSIISITWPLLFFEYEGNFIQKFQREL
::::::::::::::::::::::::: ::::::::::::::::::::::::::::::::::
NP_001 TIVEQVKEKTNHIQALAHSTVGQTLLIPLKKLFPSIISITWPLLFFEYEGNFIQKFQREL
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE6 STKWVLNTVSTGAHVLLGKILQNHMLDLRISNSKLFWRALAMLQRFSGQSKARCIESLLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 STKWVLNTVSTGAHVLLGKILQNHMLDLRISNSKLFWRALAMLQRFSGQSKARCIESLLR
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE6 AIHFPQPLSDDIRAAPISCHVQVAHEKEQVIPIALLSLLFRCSITEAQAHLAAAPSVCEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AIHFPQPLSDDIRAAPISCHVQVAHEKEQVIPIALLSLLFRCSITEAQAHLAAAPSVCEA
550 560 570 580 590 600
610 620
pF1KE6 VRSALAGPGQKRTADPLEILEPDVQ
:::::::::::::::::::::::::
NP_001 VRSALAGPGQKRTADPLEILEPDVQ
610 620
>>XP_016859285 (OMIM: 600842,613463) PREDICTED: glucokin (435 aa)
initn: 2827 init1: 2827 opt: 2827 Z-score: 3643.5 bits: 683.8 E(85289): 3.3e-196
Smith-Waterman score: 2827; 99.8% identity (99.8% similar) in 435 aa overlap (191-625:1-435)
170 180 190 200 210 220
pF1KE6 EELKKVAAGKKRVIVIGISVGLSAPFVAGQMDCCMNNTAVFLPVLVGFNPVSMARNDPIE
::::::::::::::::::::::::::::::
XP_016 MDCCMNNTAVFLPVLVGFNPVSMARNDPIE
10 20 30
230 240 250 260 270 280
pF1KE6 DWSSTFRQVAERMQKMQEKQKAFVLNPAIGPEGLSGSSRMKGGSATKILLETLLLAAHKT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DWSSTFRQVAERMQKMQEKQKAFVLNPAIGPEGLSGSSRMKGGSATKILLETLLLAAHKT
40 50 60 70 80 90
290 300 310 320 330 340
pF1KE6 VDQGIAASQRCLLEILRTFERAHQVTYSQSPKIATLMKSVSTSLEKKGHVYLVGWQTLGI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VDQGIAASQRCLLEILRTFERAHQVTYSQSPKIATLMKSVSTSLEKKGHVYLVGWQTLGI
100 110 120 130 140 150
350 360 370 380 390 400
pF1KE6 IAIMDGVECIHTFGADFRDVRGFLIGDHSDMFNQKAELTNQGPQFTFSQEDFLTSILPSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IAIMDGVECIHTFGADFRDVRGFLIGDHSDMFNQKAELTNQGPQFTFSQEDFLTSILPSL
160 170 180 190 200 210
410 420 430 440 450 460
pF1KE6 TEIDTVVFIFTLDDNLTEVQTIVEQVKEKTNHIQALAHSTVGQTLPIPLKKLFPSIISIT
::::::::::::::::::::::::::::::::::::::::::::: ::::::::::::::
XP_016 TEIDTVVFIFTLDDNLTEVQTIVEQVKEKTNHIQALAHSTVGQTLLIPLKKLFPSIISIT
220 230 240 250 260 270
470 480 490 500 510 520
pF1KE6 WPLLFFEYEGNFIQKFQRELSTKWVLNTVSTGAHVLLGKILQNHMLDLRISNSKLFWRAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 WPLLFFEYEGNFIQKFQRELSTKWVLNTVSTGAHVLLGKILQNHMLDLRISNSKLFWRAL
280 290 300 310 320 330
530 540 550 560 570 580
pF1KE6 AMLQRFSGQSKARCIESLLRAIHFPQPLSDDIRAAPISCHVQVAHEKEQVIPIALLSLLF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AMLQRFSGQSKARCIESLLRAIHFPQPLSDDIRAAPISCHVQVAHEKEQVIPIALLSLLF
340 350 360 370 380 390
590 600 610 620
pF1KE6 RCSITEAQAHLAAAPSVCEAVRSALAGPGQKRTADPLEILEPDVQ
:::::::::::::::::::::::::::::::::::::::::::::
XP_016 RCSITEAQAHLAAAPSVCEAVRSALAGPGQKRTADPLEILEPDVQ
400 410 420 430
>>XP_016859286 (OMIM: 600842,613463) PREDICTED: glucokin (435 aa)
initn: 2827 init1: 2827 opt: 2827 Z-score: 3643.5 bits: 683.8 E(85289): 3.3e-196
Smith-Waterman score: 2827; 99.8% identity (99.8% similar) in 435 aa overlap (191-625:1-435)
170 180 190 200 210 220
pF1KE6 EELKKVAAGKKRVIVIGISVGLSAPFVAGQMDCCMNNTAVFLPVLVGFNPVSMARNDPIE
::::::::::::::::::::::::::::::
XP_016 MDCCMNNTAVFLPVLVGFNPVSMARNDPIE
10 20 30
230 240 250 260 270 280
pF1KE6 DWSSTFRQVAERMQKMQEKQKAFVLNPAIGPEGLSGSSRMKGGSATKILLETLLLAAHKT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DWSSTFRQVAERMQKMQEKQKAFVLNPAIGPEGLSGSSRMKGGSATKILLETLLLAAHKT
40 50 60 70 80 90
290 300 310 320 330 340
pF1KE6 VDQGIAASQRCLLEILRTFERAHQVTYSQSPKIATLMKSVSTSLEKKGHVYLVGWQTLGI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VDQGIAASQRCLLEILRTFERAHQVTYSQSPKIATLMKSVSTSLEKKGHVYLVGWQTLGI
100 110 120 130 140 150
350 360 370 380 390 400
pF1KE6 IAIMDGVECIHTFGADFRDVRGFLIGDHSDMFNQKAELTNQGPQFTFSQEDFLTSILPSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IAIMDGVECIHTFGADFRDVRGFLIGDHSDMFNQKAELTNQGPQFTFSQEDFLTSILPSL
160 170 180 190 200 210
410 420 430 440 450 460
pF1KE6 TEIDTVVFIFTLDDNLTEVQTIVEQVKEKTNHIQALAHSTVGQTLPIPLKKLFPSIISIT
::::::::::::::::::::::::::::::::::::::::::::: ::::::::::::::
XP_016 TEIDTVVFIFTLDDNLTEVQTIVEQVKEKTNHIQALAHSTVGQTLLIPLKKLFPSIISIT
220 230 240 250 260 270
470 480 490 500 510 520
pF1KE6 WPLLFFEYEGNFIQKFQRELSTKWVLNTVSTGAHVLLGKILQNHMLDLRISNSKLFWRAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 WPLLFFEYEGNFIQKFQRELSTKWVLNTVSTGAHVLLGKILQNHMLDLRISNSKLFWRAL
280 290 300 310 320 330
530 540 550 560 570 580
pF1KE6 AMLQRFSGQSKARCIESLLRAIHFPQPLSDDIRAAPISCHVQVAHEKEQVIPIALLSLLF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AMLQRFSGQSKARCIESLLRAIHFPQPLSDDIRAAPISCHVQVAHEKEQVIPIALLSLLF
340 350 360 370 380 390
590 600 610 620
pF1KE6 RCSITEAQAHLAAAPSVCEAVRSALAGPGQKRTADPLEILEPDVQ
:::::::::::::::::::::::::::::::::::::::::::::
XP_016 RCSITEAQAHLAAAPSVCEAVRSALAGPGQKRTADPLEILEPDVQ
400 410 420 430
>>XP_011531065 (OMIM: 600842,613463) PREDICTED: glucokin (333 aa)
initn: 2071 init1: 2071 opt: 2071 Z-score: 2669.7 bits: 503.2 E(85289): 5.8e-142
Smith-Waterman score: 2071; 98.8% identity (99.4% similar) in 326 aa overlap (1-326:1-326)
10 20 30 40 50 60
pF1KE6 MPGTKRFQHVIETPEPGKWELSGYEAAVPITEKSNPLTQDLDKADAENIVRLLGQCDAEI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MPGTKRFQHVIETPEPGKWELSGYEAAVPITEKSNPLTQDLDKADAENIVRLLGQCDAEI
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 FQEEGQALSTYQRLYSESILTTMVQVAGKVQEVLKEPDGGLVVLSGGGTSGRMAFLMSVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FQEEGQALSTYQRLYSESILTTMVQVAGKVQEVLKEPDGGLVVLSGGGTSGRMAFLMSVS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 FNQLMKGLGQKPLYTYLIAGGDRSVVASREGTEDSALHGIEELKKVAAGKKRVIVIGISV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FNQLMKGLGQKPLYTYLIAGGDRSVVASREGTEDSALHGIEELKKVAAGKKRVIVIGISV
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE6 GLSAPFVAGQMDCCMNNTAVFLPVLVGFNPVSMARNDPIEDWSSTFRQVAERMQKMQEKQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GLSAPFVAGQMDCCMNNTAVFLPVLVGFNPVSMARNDPIEDWSSTFRQVAERMQKMQEKQ
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE6 KAFVLNPAIGPEGLSGSSRMKGGSATKILLETLLLAAHKTVDQGIAASQRCLLEILRTFE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KAFVLNPAIGPEGLSGSSRMKGGSATKILLETLLLAAHKTVDQGIAASQRCLLEILRTFE
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE6 RAHQVTYSQSPKIATLMKSVSTSLEKKGHVYLVGWQTLGIIAIMDGVECIHTFGADFRDV
:::::::::::::::::::::: . .
XP_011 RAHQVTYSQSPKIATLMKSVSTRFPRCPWLSHW
310 320 330
625 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Nov 8 16:01:54 2016 done: Tue Nov 8 16:01:55 2016
Total Scan time: 9.850 Total Display time: 0.020
Function used was FASTA [36.3.4 Apr, 2011]