Result of FASTA (omim) for
pFN21AE6742
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE6742, 1427 aa
1>>>pF1KE6742 1427 - 1427 aa - 1427 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.4424+/-0.000363; mu= 20.0642+/- 0.023
mean_var=152.3032+/-30.581, 0's: 0 Z-trim(118.8): 328 B-trim: 0 in 0/52
Lambda= 0.103925
statistics sampled from 31755 (32110) to 31755 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.705), E-opt: 0.2 (0.376), width: 16
Scan time: 15.700
The best scores are: opt bits E(85289)
NP_620594 (OMIM: 274150,604134) A disintegrin and (1427) 10218 1545.2 0
XP_016869721 (OMIM: 274150,604134) PREDICTED: A di (1423) 9936 1502.9 0
XP_016869722 (OMIM: 274150,604134) PREDICTED: A di (1297) 9301 1407.6 0
NP_620596 (OMIM: 274150,604134) A disintegrin and (1371) 8210 1244.1 0
XP_011516478 (OMIM: 274150,604134) PREDICTED: A di (1099) 7891 1196.2 0
XP_016869723 (OMIM: 274150,604134) PREDICTED: A di (1097) 7880 1194.5 0
XP_011516480 (OMIM: 274150,604134) PREDICTED: A di ( 982) 7030 1067.0 0
XP_011516481 (OMIM: 274150,604134) PREDICTED: A di ( 982) 6126 931.5 0
NP_620595 (OMIM: 274150,604134) A disintegrin and (1340) 6056 921.1 0
XP_016869724 (OMIM: 274150,604134) PREDICTED: A di ( 744) 5337 813.1 0
NP_008919 (OMIM: 605174) A disintegrin and metallo ( 967) 1087 176.0 1.3e-42
NP_008968 (OMIM: 605175) A disintegrin and metallo ( 889) 1029 167.2 4.9e-40
NP_005090 (OMIM: 603876) A disintegrin and metallo ( 837) 1016 165.3 1.8e-39
XP_011537603 (OMIM: 607506) PREDICTED: A disintegr ( 914) 997 162.4 1.4e-38
XP_011537604 (OMIM: 607506) PREDICTED: A disintegr ( 914) 997 162.4 1.4e-38
NP_631894 (OMIM: 607506) A disintegrin and metallo (1226) 997 162.6 1.7e-38
NP_008969 (OMIM: 605007) A disintegrin and metallo ( 930) 986 160.8 4.4e-38
NP_542453 (OMIM: 607506) A disintegrin and metallo (1223) 979 159.9 1.1e-37
NP_001307265 (OMIM: 603876) A disintegrin and meta ( 846) 971 158.5 2e-37
XP_011519614 (OMIM: 607511,613195) PREDICTED: A di (1145) 968 158.2 3.3e-37
NP_079279 (OMIM: 611681) A disintegrin and metallo (1910) 937 153.8 1.2e-35
NP_620686 (OMIM: 607509) A disintegrin and metallo ( 950) 931 152.6 1.4e-35
XP_011537056 (OMIM: 611681) PREDICTED: A disintegr (1911) 929 152.6 2.7e-35
XP_011541424 (OMIM: 605008) PREDICTED: A disintegr ( 827) 887 145.9 1.2e-33
XP_011541422 (OMIM: 605008) PREDICTED: A disintegr ( 868) 887 145.9 1.2e-33
XP_011541421 (OMIM: 605008) PREDICTED: A disintegr ( 892) 887 145.9 1.3e-33
XP_016865552 (OMIM: 225410,604539) PREDICTED: A di (1046) 875 144.2 4.9e-33
NP_055059 (OMIM: 225410,604539) A disintegrin and (1211) 875 144.3 5.4e-33
XP_011530724 (OMIM: 605011) PREDICTED: A disintegr (1177) 865 142.8 1.5e-32
XP_011530723 (OMIM: 605011) PREDICTED: A disintegr (1186) 865 142.8 1.5e-32
NP_055058 (OMIM: 605011) A disintegrin and metallo (1205) 865 142.8 1.5e-32
NP_620688 (OMIM: 607511,613195) A disintegrin and (1095) 862 142.3 2e-32
XP_005254929 (OMIM: 607511,613195) PREDICTED: A di (1122) 862 142.3 2e-32
XP_016877465 (OMIM: 607511,613195) PREDICTED: A di ( 946) 830 137.4 4.9e-31
XP_016877462 (OMIM: 607511,613195) PREDICTED: A di (1189) 830 137.5 5.7e-31
XP_016877473 (OMIM: 607511,613195) PREDICTED: A di ( 502) 824 136.2 6e-31
XP_016877467 (OMIM: 607511,613195) PREDICTED: A di ( 823) 826 136.8 6.8e-31
NP_620687 (OMIM: 607510) A disintegrin and metallo (1224) 825 136.8 9.8e-31
XP_011521226 (OMIM: 607512,615458) PREDICTED: A di ( 978) 817 135.5 1.9e-30
XP_011521225 (OMIM: 607512,615458) PREDICTED: A di (1049) 817 135.5 2e-30
NP_001313287 (OMIM: 607512,615458) A disintegrin a (1049) 817 135.5 2e-30
NP_955387 (OMIM: 607512,615458) A disintegrin and (1221) 817 135.6 2.3e-30
XP_016878478 (OMIM: 607512,615458) PREDICTED: A di ( 809) 800 132.9 1e-29
XP_016878477 (OMIM: 607512,615458) PREDICTED: A di ( 809) 800 132.9 1e-29
NP_001305710 (OMIM: 605421) A disintegrin and meta (1907) 803 133.7 1.3e-29
NP_891550 (OMIM: 605421) A disintegrin and metallo (1935) 803 133.7 1.3e-29
XP_011537611 (OMIM: 607506) PREDICTED: A disintegr ( 746) 754 125.9 1.1e-27
XP_011537602 (OMIM: 607506) PREDICTED: A disintegr (1056) 756 126.4 1.2e-27
XP_011541429 (OMIM: 605008) PREDICTED: A disintegr ( 612) 734 122.8 7.9e-27
XP_011541428 (OMIM: 605008) PREDICTED: A disintegr ( 613) 734 122.8 7.9e-27
>>NP_620594 (OMIM: 274150,604134) A disintegrin and meta (1427 aa)
initn: 10218 init1: 10218 opt: 10218 Z-score: 8283.1 bits: 1545.2 E(85289): 0
Smith-Waterman score: 10218; 100.0% identity (100.0% similar) in 1427 aa overlap (1-1427:1-1427)
10 20 30 40 50 60
pF1KE6 MHQRHPRARCPPLCVAGILACGFLLGCWGPSHFQQSCLQALEPQAVSSYLSPGAPLKGRP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_620 MHQRHPRARCPPLCVAGILACGFLLGCWGPSHFQQSCLQALEPQAVSSYLSPGAPLKGRP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 PSPGFQRQRQRQRRAAGGILHLELLVAVGPDVFQAHQEDTERYVLTNLNIGAELLRDPSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_620 PSPGFQRQRQRQRRAAGGILHLELLVAVGPDVFQAHQEDTERYVLTNLNIGAELLRDPSL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 GAQFRVHLVKMVILTEPEGAPNITANLTSSLLSVCGWSQTINPEDDTDPGHADLVLYITR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_620 GAQFRVHLVKMVILTEPEGAPNITANLTSSLLSVCGWSQTINPEDDTDPGHADLVLYITR
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE6 FDLELPDGNRQVRGVTQLGGACSPTWSCLITEDTGFDLGVTIAHEIGHSFGLEHDGAPGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_620 FDLELPDGNRQVRGVTQLGGACSPTWSCLITEDTGFDLGVTIAHEIGHSFGLEHDGAPGS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE6 GCGPSGHVMASDGAAPRAGLAWSPCSRRQLLSLLSAGRARCVWDPPRPQPGSAGHPPDAQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_620 GCGPSGHVMASDGAAPRAGLAWSPCSRRQLLSLLSAGRARCVWDPPRPQPGSAGHPPDAQ
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE6 PGLYYSANEQCRVAFGPKAVACTFAREHLDMCQALSCHTDPLDQSSCSRLLVPLLDGTEC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_620 PGLYYSANEQCRVAFGPKAVACTFAREHLDMCQALSCHTDPLDQSSCSRLLVPLLDGTEC
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE6 GVEKWCSKGRCRSLVELTPIAAVHGRWSSWGPRSPCSRSCGGGVVTRRRQCNNPRPAFGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_620 GVEKWCSKGRCRSLVELTPIAAVHGRWSSWGPRSPCSRSCGGGVVTRRRQCNNPRPAFGG
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE6 RACVGADLQAEMCNTQACEKTQLEFMSQQCARTDGQPLRSSPGGASFYHWGAAVPHSQGD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_620 RACVGADLQAEMCNTQACEKTQLEFMSQQCARTDGQPLRSSPGGASFYHWGAAVPHSQGD
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE6 ALCRHMCRAIGESFIMKRGDSFLDGTRCMPSGPREDGTLSLCVSGSCRTFGCDGRMDSQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_620 ALCRHMCRAIGESFIMKRGDSFLDGTRCMPSGPREDGTLSLCVSGSCRTFGCDGRMDSQQ
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE6 VWDRCQVCGGDNSTCSPRKGSFTAGRAREYVTFLTVTPNLTSVYIANHRPLFTHLAVRIG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_620 VWDRCQVCGGDNSTCSPRKGSFTAGRAREYVTFLTVTPNLTSVYIANHRPLFTHLAVRIG
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE6 GRYVVAGKMSISPNTTYPSLLEDGRVEYRVALTEDRLPRLEEIRIWGPLQEDADIQVYRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_620 GRYVVAGKMSISPNTTYPSLLEDGRVEYRVALTEDRLPRLEEIRIWGPLQEDADIQVYRR
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE6 YGEEYGNLTRPDITFTYFQPKPRQAWVWAAVRGPCSVSCGAGLRWVNYSCLDQARKELVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_620 YGEEYGNLTRPDITFTYFQPKPRQAWVWAAVRGPCSVSCGAGLRWVNYSCLDQARKELVE
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE6 TVQCQGSQQPPAWPEACVLEPCPPYWAVGDFGPCSASCGGGLRERPVRCVEAQGSLLKTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_620 TVQCQGSQQPPAWPEACVLEPCPPYWAVGDFGPCSASCGGGLRERPVRCVEAQGSLLKTL
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE6 PPARCRAGAQQPAVALETCNPQPCPARWEVSEPSSCTSAGGAGLALENETCVPGADGLEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_620 PPARCRAGAQQPAVALETCNPQPCPARWEVSEPSSCTSAGGAGLALENETCVPGADGLEA
790 800 810 820 830 840
850 860 870 880 890 900
pF1KE6 PVTEGPGSVDEKLPAPEPCVGMSCPPGWGHLDATSAGEKAPSPWGSIRTGAQAAHVWTPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_620 PVTEGPGSVDEKLPAPEPCVGMSCPPGWGHLDATSAGEKAPSPWGSIRTGAQAAHVWTPA
850 860 870 880 890 900
910 920 930 940 950 960
pF1KE6 AGSCSVSCGRGLMELRFLCMDSALRVPVQEELCGLASKPGSRREVCQAVPCPARWQYKLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_620 AGSCSVSCGRGLMELRFLCMDSALRVPVQEELCGLASKPGSRREVCQAVPCPARWQYKLA
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KE6 ACSVSCGRGVVRRILYCARAHGEDDGEEILLDTQCQGLPRPEPQEACSLEPCPPRWKVMS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_620 ACSVSCGRGVVRRILYCARAHGEDDGEEILLDTQCQGLPRPEPQEACSLEPCPPRWKVMS
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KE6 LGPCSASCGLGTARRSVACVQLDQGQDVEVDEAACAALVRPEASVPCLIADCTYRWHVGT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_620 LGPCSASCGLGTARRSVACVQLDQGQDVEVDEAACAALVRPEASVPCLIADCTYRWHVGT
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KE6 WMECSVSCGDGIQRRRDTCLGPQAQAPVPADFCQHLPKPVTVRGCWAGPCVGQGTPSLVP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_620 WMECSVSCGDGIQRRRDTCLGPQAQAPVPADFCQHLPKPVTVRGCWAGPCVGQGTPSLVP
1090 1100 1110 1120 1130 1140
1150 1160 1170 1180 1190 1200
pF1KE6 HEEAAAPGRTTATPAGASLEWSQARGLLFSPAPQPRRLLPGPQENSVQSSACGRQHLEPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_620 HEEAAAPGRTTATPAGASLEWSQARGLLFSPAPQPRRLLPGPQENSVQSSACGRQHLEPT
1150 1160 1170 1180 1190 1200
1210 1220 1230 1240 1250 1260
pF1KE6 GTIDMRGPGQADCAVAIGRPLGEVVTLRVLESSLNCSAGDMLLLWGRLTWRKMCRKLLDM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_620 GTIDMRGPGQADCAVAIGRPLGEVVTLRVLESSLNCSAGDMLLLWGRLTWRKMCRKLLDM
1210 1220 1230 1240 1250 1260
1270 1280 1290 1300 1310 1320
pF1KE6 TFSSKTNTLVVRQRCGRPGGGVLLRYGSQLAPETFYRECDMQLFGPWGEIVSPSLSPATS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_620 TFSSKTNTLVVRQRCGRPGGGVLLRYGSQLAPETFYRECDMQLFGPWGEIVSPSLSPATS
1270 1280 1290 1300 1310 1320
1330 1340 1350 1360 1370 1380
pF1KE6 NAGGCRLFINVAPHARIAIHALATNMGAGTEGANASYILIRDTHSLRTTAFHGQQVLYWE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_620 NAGGCRLFINVAPHARIAIHALATNMGAGTEGANASYILIRDTHSLRTTAFHGQQVLYWE
1330 1340 1350 1360 1370 1380
1390 1400 1410 1420
pF1KE6 SESSQAEMEFSEGFLKAQASLRGQYWTLQSWVPEMQDPQSWKGKEGT
:::::::::::::::::::::::::::::::::::::::::::::::
NP_620 SESSQAEMEFSEGFLKAQASLRGQYWTLQSWVPEMQDPQSWKGKEGT
1390 1400 1410 1420
>>XP_016869721 (OMIM: 274150,604134) PREDICTED: A disint (1423 aa)
initn: 9936 init1: 9936 opt: 9936 Z-score: 8054.6 bits: 1502.9 E(85289): 0
Smith-Waterman score: 9936; 99.9% identity (100.0% similar) in 1394 aa overlap (34-1427:30-1423)
10 20 30 40 50 60
pF1KE6 RHPRARCPPLCVAGILACGFLLGCWGPSHFQQSCLQALEPQAVSSYLSPGAPLKGRPPSP
..::::::::::::::::::::::::::::
XP_016 MKGIARPFVMMLRSGAVQPASATLLIRRRHRSCLQALEPQAVSSYLSPGAPLKGRPPSP
10 20 30 40 50
70 80 90 100 110 120
pF1KE6 GFQRQRQRQRRAAGGILHLELLVAVGPDVFQAHQEDTERYVLTNLNIGAELLRDPSLGAQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GFQRQRQRQRRAAGGILHLELLVAVGPDVFQAHQEDTERYVLTNLNIGAELLRDPSLGAQ
60 70 80 90 100 110
130 140 150 160 170 180
pF1KE6 FRVHLVKMVILTEPEGAPNITANLTSSLLSVCGWSQTINPEDDTDPGHADLVLYITRFDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FRVHLVKMVILTEPEGAPNITANLTSSLLSVCGWSQTINPEDDTDPGHADLVLYITRFDL
120 130 140 150 160 170
190 200 210 220 230 240
pF1KE6 ELPDGNRQVRGVTQLGGACSPTWSCLITEDTGFDLGVTIAHEIGHSFGLEHDGAPGSGCG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ELPDGNRQVRGVTQLGGACSPTWSCLITEDTGFDLGVTIAHEIGHSFGLEHDGAPGSGCG
180 190 200 210 220 230
250 260 270 280 290 300
pF1KE6 PSGHVMASDGAAPRAGLAWSPCSRRQLLSLLSAGRARCVWDPPRPQPGSAGHPPDAQPGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PSGHVMASDGAAPRAGLAWSPCSRRQLLSLLSAGRARCVWDPPRPQPGSAGHPPDAQPGL
240 250 260 270 280 290
310 320 330 340 350 360
pF1KE6 YYSANEQCRVAFGPKAVACTFAREHLDMCQALSCHTDPLDQSSCSRLLVPLLDGTECGVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YYSANEQCRVAFGPKAVACTFAREHLDMCQALSCHTDPLDQSSCSRLLVPLLDGTECGVE
300 310 320 330 340 350
370 380 390 400 410 420
pF1KE6 KWCSKGRCRSLVELTPIAAVHGRWSSWGPRSPCSRSCGGGVVTRRRQCNNPRPAFGGRAC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KWCSKGRCRSLVELTPIAAVHGRWSSWGPRSPCSRSCGGGVVTRRRQCNNPRPAFGGRAC
360 370 380 390 400 410
430 440 450 460 470 480
pF1KE6 VGADLQAEMCNTQACEKTQLEFMSQQCARTDGQPLRSSPGGASFYHWGAAVPHSQGDALC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VGADLQAEMCNTQACEKTQLEFMSQQCARTDGQPLRSSPGGASFYHWGAAVPHSQGDALC
420 430 440 450 460 470
490 500 510 520 530 540
pF1KE6 RHMCRAIGESFIMKRGDSFLDGTRCMPSGPREDGTLSLCVSGSCRTFGCDGRMDSQQVWD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RHMCRAIGESFIMKRGDSFLDGTRCMPSGPREDGTLSLCVSGSCRTFGCDGRMDSQQVWD
480 490 500 510 520 530
550 560 570 580 590 600
pF1KE6 RCQVCGGDNSTCSPRKGSFTAGRAREYVTFLTVTPNLTSVYIANHRPLFTHLAVRIGGRY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RCQVCGGDNSTCSPRKGSFTAGRAREYVTFLTVTPNLTSVYIANHRPLFTHLAVRIGGRY
540 550 560 570 580 590
610 620 630 640 650 660
pF1KE6 VVAGKMSISPNTTYPSLLEDGRVEYRVALTEDRLPRLEEIRIWGPLQEDADIQVYRRYGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VVAGKMSISPNTTYPSLLEDGRVEYRVALTEDRLPRLEEIRIWGPLQEDADIQVYRRYGE
600 610 620 630 640 650
670 680 690 700 710 720
pF1KE6 EYGNLTRPDITFTYFQPKPRQAWVWAAVRGPCSVSCGAGLRWVNYSCLDQARKELVETVQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EYGNLTRPDITFTYFQPKPRQAWVWAAVRGPCSVSCGAGLRWVNYSCLDQARKELVETVQ
660 670 680 690 700 710
730 740 750 760 770 780
pF1KE6 CQGSQQPPAWPEACVLEPCPPYWAVGDFGPCSASCGGGLRERPVRCVEAQGSLLKTLPPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CQGSQQPPAWPEACVLEPCPPYWAVGDFGPCSASCGGGLRERPVRCVEAQGSLLKTLPPA
720 730 740 750 760 770
790 800 810 820 830 840
pF1KE6 RCRAGAQQPAVALETCNPQPCPARWEVSEPSSCTSAGGAGLALENETCVPGADGLEAPVT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RCRAGAQQPAVALETCNPQPCPARWEVSEPSSCTSAGGAGLALENETCVPGADGLEAPVT
780 790 800 810 820 830
850 860 870 880 890 900
pF1KE6 EGPGSVDEKLPAPEPCVGMSCPPGWGHLDATSAGEKAPSPWGSIRTGAQAAHVWTPAAGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EGPGSVDEKLPAPEPCVGMSCPPGWGHLDATSAGEKAPSPWGSIRTGAQAAHVWTPAAGS
840 850 860 870 880 890
910 920 930 940 950 960
pF1KE6 CSVSCGRGLMELRFLCMDSALRVPVQEELCGLASKPGSRREVCQAVPCPARWQYKLAACS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CSVSCGRGLMELRFLCMDSALRVPVQEELCGLASKPGSRREVCQAVPCPARWQYKLAACS
900 910 920 930 940 950
970 980 990 1000 1010 1020
pF1KE6 VSCGRGVVRRILYCARAHGEDDGEEILLDTQCQGLPRPEPQEACSLEPCPPRWKVMSLGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VSCGRGVVRRILYCARAHGEDDGEEILLDTQCQGLPRPEPQEACSLEPCPPRWKVMSLGP
960 970 980 990 1000 1010
1030 1040 1050 1060 1070 1080
pF1KE6 CSASCGLGTARRSVACVQLDQGQDVEVDEAACAALVRPEASVPCLIADCTYRWHVGTWME
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CSASCGLGTARRSVACVQLDQGQDVEVDEAACAALVRPEASVPCLIADCTYRWHVGTWME
1020 1030 1040 1050 1060 1070
1090 1100 1110 1120 1130 1140
pF1KE6 CSVSCGDGIQRRRDTCLGPQAQAPVPADFCQHLPKPVTVRGCWAGPCVGQGTPSLVPHEE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CSVSCGDGIQRRRDTCLGPQAQAPVPADFCQHLPKPVTVRGCWAGPCVGQGTPSLVPHEE
1080 1090 1100 1110 1120 1130
1150 1160 1170 1180 1190 1200
pF1KE6 AAAPGRTTATPAGASLEWSQARGLLFSPAPQPRRLLPGPQENSVQSSACGRQHLEPTGTI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AAAPGRTTATPAGASLEWSQARGLLFSPAPQPRRLLPGPQENSVQSSACGRQHLEPTGTI
1140 1150 1160 1170 1180 1190
1210 1220 1230 1240 1250 1260
pF1KE6 DMRGPGQADCAVAIGRPLGEVVTLRVLESSLNCSAGDMLLLWGRLTWRKMCRKLLDMTFS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DMRGPGQADCAVAIGRPLGEVVTLRVLESSLNCSAGDMLLLWGRLTWRKMCRKLLDMTFS
1200 1210 1220 1230 1240 1250
1270 1280 1290 1300 1310 1320
pF1KE6 SKTNTLVVRQRCGRPGGGVLLRYGSQLAPETFYRECDMQLFGPWGEIVSPSLSPATSNAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SKTNTLVVRQRCGRPGGGVLLRYGSQLAPETFYRECDMQLFGPWGEIVSPSLSPATSNAG
1260 1270 1280 1290 1300 1310
1330 1340 1350 1360 1370 1380
pF1KE6 GCRLFINVAPHARIAIHALATNMGAGTEGANASYILIRDTHSLRTTAFHGQQVLYWESES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GCRLFINVAPHARIAIHALATNMGAGTEGANASYILIRDTHSLRTTAFHGQQVLYWESES
1320 1330 1340 1350 1360 1370
1390 1400 1410 1420
pF1KE6 SQAEMEFSEGFLKAQASLRGQYWTLQSWVPEMQDPQSWKGKEGT
::::::::::::::::::::::::::::::::::::::::::::
XP_016 SQAEMEFSEGFLKAQASLRGQYWTLQSWVPEMQDPQSWKGKEGT
1380 1390 1400 1410 1420
>>XP_016869722 (OMIM: 274150,604134) PREDICTED: A disint (1297 aa)
initn: 9301 init1: 9301 opt: 9301 Z-score: 7540.5 bits: 1407.6 E(85289): 0
Smith-Waterman score: 9301; 100.0% identity (100.0% similar) in 1297 aa overlap (131-1427:1-1297)
110 120 130 140 150 160
pF1KE6 ERYVLTNLNIGAELLRDPSLGAQFRVHLVKMVILTEPEGAPNITANLTSSLLSVCGWSQT
::::::::::::::::::::::::::::::
XP_016 MVILTEPEGAPNITANLTSSLLSVCGWSQT
10 20 30
170 180 190 200 210 220
pF1KE6 INPEDDTDPGHADLVLYITRFDLELPDGNRQVRGVTQLGGACSPTWSCLITEDTGFDLGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 INPEDDTDPGHADLVLYITRFDLELPDGNRQVRGVTQLGGACSPTWSCLITEDTGFDLGV
40 50 60 70 80 90
230 240 250 260 270 280
pF1KE6 TIAHEIGHSFGLEHDGAPGSGCGPSGHVMASDGAAPRAGLAWSPCSRRQLLSLLSAGRAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TIAHEIGHSFGLEHDGAPGSGCGPSGHVMASDGAAPRAGLAWSPCSRRQLLSLLSAGRAR
100 110 120 130 140 150
290 300 310 320 330 340
pF1KE6 CVWDPPRPQPGSAGHPPDAQPGLYYSANEQCRVAFGPKAVACTFAREHLDMCQALSCHTD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CVWDPPRPQPGSAGHPPDAQPGLYYSANEQCRVAFGPKAVACTFAREHLDMCQALSCHTD
160 170 180 190 200 210
350 360 370 380 390 400
pF1KE6 PLDQSSCSRLLVPLLDGTECGVEKWCSKGRCRSLVELTPIAAVHGRWSSWGPRSPCSRSC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PLDQSSCSRLLVPLLDGTECGVEKWCSKGRCRSLVELTPIAAVHGRWSSWGPRSPCSRSC
220 230 240 250 260 270
410 420 430 440 450 460
pF1KE6 GGGVVTRRRQCNNPRPAFGGRACVGADLQAEMCNTQACEKTQLEFMSQQCARTDGQPLRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GGGVVTRRRQCNNPRPAFGGRACVGADLQAEMCNTQACEKTQLEFMSQQCARTDGQPLRS
280 290 300 310 320 330
470 480 490 500 510 520
pF1KE6 SPGGASFYHWGAAVPHSQGDALCRHMCRAIGESFIMKRGDSFLDGTRCMPSGPREDGTLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SPGGASFYHWGAAVPHSQGDALCRHMCRAIGESFIMKRGDSFLDGTRCMPSGPREDGTLS
340 350 360 370 380 390
530 540 550 560 570 580
pF1KE6 LCVSGSCRTFGCDGRMDSQQVWDRCQVCGGDNSTCSPRKGSFTAGRAREYVTFLTVTPNL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LCVSGSCRTFGCDGRMDSQQVWDRCQVCGGDNSTCSPRKGSFTAGRAREYVTFLTVTPNL
400 410 420 430 440 450
590 600 610 620 630 640
pF1KE6 TSVYIANHRPLFTHLAVRIGGRYVVAGKMSISPNTTYPSLLEDGRVEYRVALTEDRLPRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TSVYIANHRPLFTHLAVRIGGRYVVAGKMSISPNTTYPSLLEDGRVEYRVALTEDRLPRL
460 470 480 490 500 510
650 660 670 680 690 700
pF1KE6 EEIRIWGPLQEDADIQVYRRYGEEYGNLTRPDITFTYFQPKPRQAWVWAAVRGPCSVSCG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EEIRIWGPLQEDADIQVYRRYGEEYGNLTRPDITFTYFQPKPRQAWVWAAVRGPCSVSCG
520 530 540 550 560 570
710 720 730 740 750 760
pF1KE6 AGLRWVNYSCLDQARKELVETVQCQGSQQPPAWPEACVLEPCPPYWAVGDFGPCSASCGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AGLRWVNYSCLDQARKELVETVQCQGSQQPPAWPEACVLEPCPPYWAVGDFGPCSASCGG
580 590 600 610 620 630
770 780 790 800 810 820
pF1KE6 GLRERPVRCVEAQGSLLKTLPPARCRAGAQQPAVALETCNPQPCPARWEVSEPSSCTSAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GLRERPVRCVEAQGSLLKTLPPARCRAGAQQPAVALETCNPQPCPARWEVSEPSSCTSAG
640 650 660 670 680 690
830 840 850 860 870 880
pF1KE6 GAGLALENETCVPGADGLEAPVTEGPGSVDEKLPAPEPCVGMSCPPGWGHLDATSAGEKA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GAGLALENETCVPGADGLEAPVTEGPGSVDEKLPAPEPCVGMSCPPGWGHLDATSAGEKA
700 710 720 730 740 750
890 900 910 920 930 940
pF1KE6 PSPWGSIRTGAQAAHVWTPAAGSCSVSCGRGLMELRFLCMDSALRVPVQEELCGLASKPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PSPWGSIRTGAQAAHVWTPAAGSCSVSCGRGLMELRFLCMDSALRVPVQEELCGLASKPG
760 770 780 790 800 810
950 960 970 980 990 1000
pF1KE6 SRREVCQAVPCPARWQYKLAACSVSCGRGVVRRILYCARAHGEDDGEEILLDTQCQGLPR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SRREVCQAVPCPARWQYKLAACSVSCGRGVVRRILYCARAHGEDDGEEILLDTQCQGLPR
820 830 840 850 860 870
1010 1020 1030 1040 1050 1060
pF1KE6 PEPQEACSLEPCPPRWKVMSLGPCSASCGLGTARRSVACVQLDQGQDVEVDEAACAALVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PEPQEACSLEPCPPRWKVMSLGPCSASCGLGTARRSVACVQLDQGQDVEVDEAACAALVR
880 890 900 910 920 930
1070 1080 1090 1100 1110 1120
pF1KE6 PEASVPCLIADCTYRWHVGTWMECSVSCGDGIQRRRDTCLGPQAQAPVPADFCQHLPKPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PEASVPCLIADCTYRWHVGTWMECSVSCGDGIQRRRDTCLGPQAQAPVPADFCQHLPKPV
940 950 960 970 980 990
1130 1140 1150 1160 1170 1180
pF1KE6 TVRGCWAGPCVGQGTPSLVPHEEAAAPGRTTATPAGASLEWSQARGLLFSPAPQPRRLLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TVRGCWAGPCVGQGTPSLVPHEEAAAPGRTTATPAGASLEWSQARGLLFSPAPQPRRLLP
1000 1010 1020 1030 1040 1050
1190 1200 1210 1220 1230 1240
pF1KE6 GPQENSVQSSACGRQHLEPTGTIDMRGPGQADCAVAIGRPLGEVVTLRVLESSLNCSAGD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GPQENSVQSSACGRQHLEPTGTIDMRGPGQADCAVAIGRPLGEVVTLRVLESSLNCSAGD
1060 1070 1080 1090 1100 1110
1250 1260 1270 1280 1290 1300
pF1KE6 MLLLWGRLTWRKMCRKLLDMTFSSKTNTLVVRQRCGRPGGGVLLRYGSQLAPETFYRECD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MLLLWGRLTWRKMCRKLLDMTFSSKTNTLVVRQRCGRPGGGVLLRYGSQLAPETFYRECD
1120 1130 1140 1150 1160 1170
1310 1320 1330 1340 1350 1360
pF1KE6 MQLFGPWGEIVSPSLSPATSNAGGCRLFINVAPHARIAIHALATNMGAGTEGANASYILI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MQLFGPWGEIVSPSLSPATSNAGGCRLFINVAPHARIAIHALATNMGAGTEGANASYILI
1180 1190 1200 1210 1220 1230
1370 1380 1390 1400 1410 1420
pF1KE6 RDTHSLRTTAFHGQQVLYWESESSQAEMEFSEGFLKAQASLRGQYWTLQSWVPEMQDPQS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RDTHSLRTTAFHGQQVLYWESESSQAEMEFSEGFLKAQASLRGQYWTLQSWVPEMQDPQS
1240 1250 1260 1270 1280 1290
pF1KE6 WKGKEGT
:::::::
XP_016 WKGKEGT
>>NP_620596 (OMIM: 274150,604134) A disintegrin and meta (1371 aa)
initn: 8210 init1: 8210 opt: 8210 Z-score: 6656.2 bits: 1244.1 E(85289): 0
Smith-Waterman score: 9719; 96.1% identity (96.1% similar) in 1427 aa overlap (1-1427:1-1371)
10 20 30 40 50 60
pF1KE6 MHQRHPRARCPPLCVAGILACGFLLGCWGPSHFQQSCLQALEPQAVSSYLSPGAPLKGRP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_620 MHQRHPRARCPPLCVAGILACGFLLGCWGPSHFQQSCLQALEPQAVSSYLSPGAPLKGRP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 PSPGFQRQRQRQRRAAGGILHLELLVAVGPDVFQAHQEDTERYVLTNLNIGAELLRDPSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_620 PSPGFQRQRQRQRRAAGGILHLELLVAVGPDVFQAHQEDTERYVLTNLNIGAELLRDPSL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 GAQFRVHLVKMVILTEPEGAPNITANLTSSLLSVCGWSQTINPEDDTDPGHADLVLYITR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_620 GAQFRVHLVKMVILTEPEGAPNITANLTSSLLSVCGWSQTINPEDDTDPGHADLVLYITR
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE6 FDLELPDGNRQVRGVTQLGGACSPTWSCLITEDTGFDLGVTIAHEIGHSFGLEHDGAPGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_620 FDLELPDGNRQVRGVTQLGGACSPTWSCLITEDTGFDLGVTIAHEIGHSFGLEHDGAPGS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE6 GCGPSGHVMASDGAAPRAGLAWSPCSRRQLLSLLSAGRARCVWDPPRPQPGSAGHPPDAQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_620 GCGPSGHVMASDGAAPRAGLAWSPCSRRQLLSLLSAGRARCVWDPPRPQPGSAGHPPDAQ
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE6 PGLYYSANEQCRVAFGPKAVACTFAREHLDMCQALSCHTDPLDQSSCSRLLVPLLDGTEC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_620 PGLYYSANEQCRVAFGPKAVACTFAREHLDMCQALSCHTDPLDQSSCSRLLVPLLDGTEC
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE6 GVEKWCSKGRCRSLVELTPIAAVHGRWSSWGPRSPCSRSCGGGVVTRRRQCNNPRPAFGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_620 GVEKWCSKGRCRSLVELTPIAAVHGRWSSWGPRSPCSRSCGGGVVTRRRQCNNPRPAFGG
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE6 RACVGADLQAEMCNTQACEKTQLEFMSQQCARTDGQPLRSSPGGASFYHWGAAVPHSQGD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_620 RACVGADLQAEMCNTQACEKTQLEFMSQQCARTDGQPLRSSPGGASFYHWGAAVPHSQGD
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE6 ALCRHMCRAIGESFIMKRGDSFLDGTRCMPSGPREDGTLSLCVSGSCRTFGCDGRMDSQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_620 ALCRHMCRAIGESFIMKRGDSFLDGTRCMPSGPREDGTLSLCVSGSCRTFGCDGRMDSQQ
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE6 VWDRCQVCGGDNSTCSPRKGSFTAGRAREYVTFLTVTPNLTSVYIANHRPLFTHLAVRIG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_620 VWDRCQVCGGDNSTCSPRKGSFTAGRAREYVTFLTVTPNLTSVYIANHRPLFTHLAVRIG
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE6 GRYVVAGKMSISPNTTYPSLLEDGRVEYRVALTEDRLPRLEEIRIWGPLQEDADIQVYRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_620 GRYVVAGKMSISPNTTYPSLLEDGRVEYRVALTEDRLPRLEEIRIWGPLQEDADIQVYRR
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE6 YGEEYGNLTRPDITFTYFQPKPRQAWVWAAVRGPCSVSCGAGLRWVNYSCLDQARKELVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_620 YGEEYGNLTRPDITFTYFQPKPRQAWVWAAVRGPCSVSCGAGLRWVNYSCLDQARKELVE
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE6 TVQCQGSQQPPAWPEACVLEPCPPYWAVGDFGPCSASCGGGLRERPVRCVEAQGSLLKTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_620 TVQCQGSQQPPAWPEACVLEPCPPYWAVGDFGPCSASCGGGLRERPVRCVEAQGSLLKTL
730 740 750 760 770 780
790 800 810 820 830 840
pF1KE6 PPARCRAGAQQPAVALETCNPQPCPARWEVSEPSSCTSAGGAGLALENETCVPGADGLEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_620 PPARCRAGAQQPAVALETCNPQPCPARWEVSEPSSCTSAGGAGLALENETCVPGADGLEA
790 800 810 820 830 840
850 860 870 880 890 900
pF1KE6 PVTEGPGSVDEKLPAPEPCVGMSCPPGWGHLDATSAGEKAPSPWGSIRTGAQAAHVWTPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_620 PVTEGPGSVDEKLPAPEPCVGMSCPPGWGHLDATSAGEKAPSPWGSIRTGAQAAHVWTPA
850 860 870 880 890 900
910 920 930 940 950 960
pF1KE6 AGSCSVSCGRGLMELRFLCMDSALRVPVQEELCGLASKPGSRREVCQAVPCPARWQYKLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_620 AGSCSVSCGRGLMELRFLCMDSALRVPVQEELCGLASKPGSRREVCQAVPCPARWQYKLA
910 920 930 940 950 960
970 980 990 1000 1010 1020
pF1KE6 ACSVSCGRGVVRRILYCARAHGEDDGEEILLDTQCQGLPRPEPQEACSLEPCPPRWKVMS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_620 ACSVSCGRGVVRRILYCARAHGEDDGEEILLDTQCQGLPRPEPQEACSLEPCPPRWKVMS
970 980 990 1000 1010 1020
1030 1040 1050 1060 1070 1080
pF1KE6 LGPCSASCGLGTARRSVACVQLDQGQDVEVDEAACAALVRPEASVPCLIADCTYRWHVGT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_620 LGPCSASCGLGTARRSVACVQLDQGQDVEVDEAACAALVRPEASVPCLIADCTYRWHVGT
1030 1040 1050 1060 1070 1080
1090 1100 1110 1120 1130 1140
pF1KE6 WMECSVSCGDGIQRRRDTCLGPQAQAPVPADFCQHLPKPVTVRGCWAGPCVGQGTPSLVP
::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_620 WMECSVSCGDGIQRRRDTCLGPQAQAPVPADFCQHLPKPVTVRGCWAGPCVGQG------
1090 1100 1110 1120 1130
1150 1160 1170 1180 1190 1200
pF1KE6 HEEAAAPGRTTATPAGASLEWSQARGLLFSPAPQPRRLLPGPQENSVQSSACGRQHLEPT
::::::::::
NP_620 --------------------------------------------------ACGRQHLEPT
1140
1210 1220 1230 1240 1250 1260
pF1KE6 GTIDMRGPGQADCAVAIGRPLGEVVTLRVLESSLNCSAGDMLLLWGRLTWRKMCRKLLDM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_620 GTIDMRGPGQADCAVAIGRPLGEVVTLRVLESSLNCSAGDMLLLWGRLTWRKMCRKLLDM
1150 1160 1170 1180 1190 1200
1270 1280 1290 1300 1310 1320
pF1KE6 TFSSKTNTLVVRQRCGRPGGGVLLRYGSQLAPETFYRECDMQLFGPWGEIVSPSLSPATS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_620 TFSSKTNTLVVRQRCGRPGGGVLLRYGSQLAPETFYRECDMQLFGPWGEIVSPSLSPATS
1210 1220 1230 1240 1250 1260
1330 1340 1350 1360 1370 1380
pF1KE6 NAGGCRLFINVAPHARIAIHALATNMGAGTEGANASYILIRDTHSLRTTAFHGQQVLYWE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_620 NAGGCRLFINVAPHARIAIHALATNMGAGTEGANASYILIRDTHSLRTTAFHGQQVLYWE
1270 1280 1290 1300 1310 1320
1390 1400 1410 1420
pF1KE6 SESSQAEMEFSEGFLKAQASLRGQYWTLQSWVPEMQDPQSWKGKEGT
:::::::::::::::::::::::::::::::::::::::::::::::
NP_620 SESSQAEMEFSEGFLKAQASLRGQYWTLQSWVPEMQDPQSWKGKEGT
1330 1340 1350 1360 1370
>>XP_011516478 (OMIM: 274150,604134) PREDICTED: A disint (1099 aa)
initn: 7891 init1: 7891 opt: 7891 Z-score: 6398.9 bits: 1196.2 E(85289): 0
Smith-Waterman score: 7891; 99.9% identity (100.0% similar) in 1099 aa overlap (329-1427:1-1099)
300 310 320 330 340 350
pF1KE6 AQPGLYYSANEQCRVAFGPKAVACTFAREHLDMCQALSCHTDPLDQSSCSRLLVPLLDGT
.:::::::::::::::::::::::::::::
XP_011 MDMCQALSCHTDPLDQSSCSRLLVPLLDGT
10 20 30
360 370 380 390 400 410
pF1KE6 ECGVEKWCSKGRCRSLVELTPIAAVHGRWSSWGPRSPCSRSCGGGVVTRRRQCNNPRPAF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ECGVEKWCSKGRCRSLVELTPIAAVHGRWSSWGPRSPCSRSCGGGVVTRRRQCNNPRPAF
40 50 60 70 80 90
420 430 440 450 460 470
pF1KE6 GGRACVGADLQAEMCNTQACEKTQLEFMSQQCARTDGQPLRSSPGGASFYHWGAAVPHSQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GGRACVGADLQAEMCNTQACEKTQLEFMSQQCARTDGQPLRSSPGGASFYHWGAAVPHSQ
100 110 120 130 140 150
480 490 500 510 520 530
pF1KE6 GDALCRHMCRAIGESFIMKRGDSFLDGTRCMPSGPREDGTLSLCVSGSCRTFGCDGRMDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GDALCRHMCRAIGESFIMKRGDSFLDGTRCMPSGPREDGTLSLCVSGSCRTFGCDGRMDS
160 170 180 190 200 210
540 550 560 570 580 590
pF1KE6 QQVWDRCQVCGGDNSTCSPRKGSFTAGRAREYVTFLTVTPNLTSVYIANHRPLFTHLAVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QQVWDRCQVCGGDNSTCSPRKGSFTAGRAREYVTFLTVTPNLTSVYIANHRPLFTHLAVR
220 230 240 250 260 270
600 610 620 630 640 650
pF1KE6 IGGRYVVAGKMSISPNTTYPSLLEDGRVEYRVALTEDRLPRLEEIRIWGPLQEDADIQVY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IGGRYVVAGKMSISPNTTYPSLLEDGRVEYRVALTEDRLPRLEEIRIWGPLQEDADIQVY
280 290 300 310 320 330
660 670 680 690 700 710
pF1KE6 RRYGEEYGNLTRPDITFTYFQPKPRQAWVWAAVRGPCSVSCGAGLRWVNYSCLDQARKEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RRYGEEYGNLTRPDITFTYFQPKPRQAWVWAAVRGPCSVSCGAGLRWVNYSCLDQARKEL
340 350 360 370 380 390
720 730 740 750 760 770
pF1KE6 VETVQCQGSQQPPAWPEACVLEPCPPYWAVGDFGPCSASCGGGLRERPVRCVEAQGSLLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VETVQCQGSQQPPAWPEACVLEPCPPYWAVGDFGPCSASCGGGLRERPVRCVEAQGSLLK
400 410 420 430 440 450
780 790 800 810 820 830
pF1KE6 TLPPARCRAGAQQPAVALETCNPQPCPARWEVSEPSSCTSAGGAGLALENETCVPGADGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TLPPARCRAGAQQPAVALETCNPQPCPARWEVSEPSSCTSAGGAGLALENETCVPGADGL
460 470 480 490 500 510
840 850 860 870 880 890
pF1KE6 EAPVTEGPGSVDEKLPAPEPCVGMSCPPGWGHLDATSAGEKAPSPWGSIRTGAQAAHVWT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EAPVTEGPGSVDEKLPAPEPCVGMSCPPGWGHLDATSAGEKAPSPWGSIRTGAQAAHVWT
520 530 540 550 560 570
900 910 920 930 940 950
pF1KE6 PAAGSCSVSCGRGLMELRFLCMDSALRVPVQEELCGLASKPGSRREVCQAVPCPARWQYK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PAAGSCSVSCGRGLMELRFLCMDSALRVPVQEELCGLASKPGSRREVCQAVPCPARWQYK
580 590 600 610 620 630
960 970 980 990 1000 1010
pF1KE6 LAACSVSCGRGVVRRILYCARAHGEDDGEEILLDTQCQGLPRPEPQEACSLEPCPPRWKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LAACSVSCGRGVVRRILYCARAHGEDDGEEILLDTQCQGLPRPEPQEACSLEPCPPRWKV
640 650 660 670 680 690
1020 1030 1040 1050 1060 1070
pF1KE6 MSLGPCSASCGLGTARRSVACVQLDQGQDVEVDEAACAALVRPEASVPCLIADCTYRWHV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MSLGPCSASCGLGTARRSVACVQLDQGQDVEVDEAACAALVRPEASVPCLIADCTYRWHV
700 710 720 730 740 750
1080 1090 1100 1110 1120 1130
pF1KE6 GTWMECSVSCGDGIQRRRDTCLGPQAQAPVPADFCQHLPKPVTVRGCWAGPCVGQGTPSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GTWMECSVSCGDGIQRRRDTCLGPQAQAPVPADFCQHLPKPVTVRGCWAGPCVGQGTPSL
760 770 780 790 800 810
1140 1150 1160 1170 1180 1190
pF1KE6 VPHEEAAAPGRTTATPAGASLEWSQARGLLFSPAPQPRRLLPGPQENSVQSSACGRQHLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VPHEEAAAPGRTTATPAGASLEWSQARGLLFSPAPQPRRLLPGPQENSVQSSACGRQHLE
820 830 840 850 860 870
1200 1210 1220 1230 1240 1250
pF1KE6 PTGTIDMRGPGQADCAVAIGRPLGEVVTLRVLESSLNCSAGDMLLLWGRLTWRKMCRKLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PTGTIDMRGPGQADCAVAIGRPLGEVVTLRVLESSLNCSAGDMLLLWGRLTWRKMCRKLL
880 890 900 910 920 930
1260 1270 1280 1290 1300 1310
pF1KE6 DMTFSSKTNTLVVRQRCGRPGGGVLLRYGSQLAPETFYRECDMQLFGPWGEIVSPSLSPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DMTFSSKTNTLVVRQRCGRPGGGVLLRYGSQLAPETFYRECDMQLFGPWGEIVSPSLSPA
940 950 960 970 980 990
1320 1330 1340 1350 1360 1370
pF1KE6 TSNAGGCRLFINVAPHARIAIHALATNMGAGTEGANASYILIRDTHSLRTTAFHGQQVLY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TSNAGGCRLFINVAPHARIAIHALATNMGAGTEGANASYILIRDTHSLRTTAFHGQQVLY
1000 1010 1020 1030 1040 1050
1380 1390 1400 1410 1420
pF1KE6 WESESSQAEMEFSEGFLKAQASLRGQYWTLQSWVPEMQDPQSWKGKEGT
:::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 WESESSQAEMEFSEGFLKAQASLRGQYWTLQSWVPEMQDPQSWKGKEGT
1060 1070 1080 1090
>>XP_016869723 (OMIM: 274150,604134) PREDICTED: A disint (1097 aa)
initn: 7880 init1: 7880 opt: 7880 Z-score: 6390.0 bits: 1194.5 E(85289): 0
Smith-Waterman score: 7880; 100.0% identity (100.0% similar) in 1097 aa overlap (331-1427:1-1097)
310 320 330 340 350 360
pF1KE6 PGLYYSANEQCRVAFGPKAVACTFAREHLDMCQALSCHTDPLDQSSCSRLLVPLLDGTEC
::::::::::::::::::::::::::::::
XP_016 MCQALSCHTDPLDQSSCSRLLVPLLDGTEC
10 20 30
370 380 390 400 410 420
pF1KE6 GVEKWCSKGRCRSLVELTPIAAVHGRWSSWGPRSPCSRSCGGGVVTRRRQCNNPRPAFGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GVEKWCSKGRCRSLVELTPIAAVHGRWSSWGPRSPCSRSCGGGVVTRRRQCNNPRPAFGG
40 50 60 70 80 90
430 440 450 460 470 480
pF1KE6 RACVGADLQAEMCNTQACEKTQLEFMSQQCARTDGQPLRSSPGGASFYHWGAAVPHSQGD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RACVGADLQAEMCNTQACEKTQLEFMSQQCARTDGQPLRSSPGGASFYHWGAAVPHSQGD
100 110 120 130 140 150
490 500 510 520 530 540
pF1KE6 ALCRHMCRAIGESFIMKRGDSFLDGTRCMPSGPREDGTLSLCVSGSCRTFGCDGRMDSQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ALCRHMCRAIGESFIMKRGDSFLDGTRCMPSGPREDGTLSLCVSGSCRTFGCDGRMDSQQ
160 170 180 190 200 210
550 560 570 580 590 600
pF1KE6 VWDRCQVCGGDNSTCSPRKGSFTAGRAREYVTFLTVTPNLTSVYIANHRPLFTHLAVRIG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VWDRCQVCGGDNSTCSPRKGSFTAGRAREYVTFLTVTPNLTSVYIANHRPLFTHLAVRIG
220 230 240 250 260 270
610 620 630 640 650 660
pF1KE6 GRYVVAGKMSISPNTTYPSLLEDGRVEYRVALTEDRLPRLEEIRIWGPLQEDADIQVYRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GRYVVAGKMSISPNTTYPSLLEDGRVEYRVALTEDRLPRLEEIRIWGPLQEDADIQVYRR
280 290 300 310 320 330
670 680 690 700 710 720
pF1KE6 YGEEYGNLTRPDITFTYFQPKPRQAWVWAAVRGPCSVSCGAGLRWVNYSCLDQARKELVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YGEEYGNLTRPDITFTYFQPKPRQAWVWAAVRGPCSVSCGAGLRWVNYSCLDQARKELVE
340 350 360 370 380 390
730 740 750 760 770 780
pF1KE6 TVQCQGSQQPPAWPEACVLEPCPPYWAVGDFGPCSASCGGGLRERPVRCVEAQGSLLKTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TVQCQGSQQPPAWPEACVLEPCPPYWAVGDFGPCSASCGGGLRERPVRCVEAQGSLLKTL
400 410 420 430 440 450
790 800 810 820 830 840
pF1KE6 PPARCRAGAQQPAVALETCNPQPCPARWEVSEPSSCTSAGGAGLALENETCVPGADGLEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PPARCRAGAQQPAVALETCNPQPCPARWEVSEPSSCTSAGGAGLALENETCVPGADGLEA
460 470 480 490 500 510
850 860 870 880 890 900
pF1KE6 PVTEGPGSVDEKLPAPEPCVGMSCPPGWGHLDATSAGEKAPSPWGSIRTGAQAAHVWTPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PVTEGPGSVDEKLPAPEPCVGMSCPPGWGHLDATSAGEKAPSPWGSIRTGAQAAHVWTPA
520 530 540 550 560 570
910 920 930 940 950 960
pF1KE6 AGSCSVSCGRGLMELRFLCMDSALRVPVQEELCGLASKPGSRREVCQAVPCPARWQYKLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AGSCSVSCGRGLMELRFLCMDSALRVPVQEELCGLASKPGSRREVCQAVPCPARWQYKLA
580 590 600 610 620 630
970 980 990 1000 1010 1020
pF1KE6 ACSVSCGRGVVRRILYCARAHGEDDGEEILLDTQCQGLPRPEPQEACSLEPCPPRWKVMS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ACSVSCGRGVVRRILYCARAHGEDDGEEILLDTQCQGLPRPEPQEACSLEPCPPRWKVMS
640 650 660 670 680 690
1030 1040 1050 1060 1070 1080
pF1KE6 LGPCSASCGLGTARRSVACVQLDQGQDVEVDEAACAALVRPEASVPCLIADCTYRWHVGT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LGPCSASCGLGTARRSVACVQLDQGQDVEVDEAACAALVRPEASVPCLIADCTYRWHVGT
700 710 720 730 740 750
1090 1100 1110 1120 1130 1140
pF1KE6 WMECSVSCGDGIQRRRDTCLGPQAQAPVPADFCQHLPKPVTVRGCWAGPCVGQGTPSLVP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 WMECSVSCGDGIQRRRDTCLGPQAQAPVPADFCQHLPKPVTVRGCWAGPCVGQGTPSLVP
760 770 780 790 800 810
1150 1160 1170 1180 1190 1200
pF1KE6 HEEAAAPGRTTATPAGASLEWSQARGLLFSPAPQPRRLLPGPQENSVQSSACGRQHLEPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HEEAAAPGRTTATPAGASLEWSQARGLLFSPAPQPRRLLPGPQENSVQSSACGRQHLEPT
820 830 840 850 860 870
1210 1220 1230 1240 1250 1260
pF1KE6 GTIDMRGPGQADCAVAIGRPLGEVVTLRVLESSLNCSAGDMLLLWGRLTWRKMCRKLLDM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GTIDMRGPGQADCAVAIGRPLGEVVTLRVLESSLNCSAGDMLLLWGRLTWRKMCRKLLDM
880 890 900 910 920 930
1270 1280 1290 1300 1310 1320
pF1KE6 TFSSKTNTLVVRQRCGRPGGGVLLRYGSQLAPETFYRECDMQLFGPWGEIVSPSLSPATS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TFSSKTNTLVVRQRCGRPGGGVLLRYGSQLAPETFYRECDMQLFGPWGEIVSPSLSPATS
940 950 960 970 980 990
1330 1340 1350 1360 1370 1380
pF1KE6 NAGGCRLFINVAPHARIAIHALATNMGAGTEGANASYILIRDTHSLRTTAFHGQQVLYWE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NAGGCRLFINVAPHARIAIHALATNMGAGTEGANASYILIRDTHSLRTTAFHGQQVLYWE
1000 1010 1020 1030 1040 1050
1390 1400 1410 1420
pF1KE6 SESSQAEMEFSEGFLKAQASLRGQYWTLQSWVPEMQDPQSWKGKEGT
:::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SESSQAEMEFSEGFLKAQASLRGQYWTLQSWVPEMQDPQSWKGKEGT
1060 1070 1080 1090
>>XP_011516480 (OMIM: 274150,604134) PREDICTED: A disint (982 aa)
initn: 7030 init1: 7030 opt: 7030 Z-score: 5701.8 bits: 1067.0 E(85289): 0
Smith-Waterman score: 7030; 100.0% identity (100.0% similar) in 982 aa overlap (446-1427:1-982)
420 430 440 450 460 470
pF1KE6 PAFGGRACVGADLQAEMCNTQACEKTQLEFMSQQCARTDGQPLRSSPGGASFYHWGAAVP
::::::::::::::::::::::::::::::
XP_011 MSQQCARTDGQPLRSSPGGASFYHWGAAVP
10 20 30
480 490 500 510 520 530
pF1KE6 HSQGDALCRHMCRAIGESFIMKRGDSFLDGTRCMPSGPREDGTLSLCVSGSCRTFGCDGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HSQGDALCRHMCRAIGESFIMKRGDSFLDGTRCMPSGPREDGTLSLCVSGSCRTFGCDGR
40 50 60 70 80 90
540 550 560 570 580 590
pF1KE6 MDSQQVWDRCQVCGGDNSTCSPRKGSFTAGRAREYVTFLTVTPNLTSVYIANHRPLFTHL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MDSQQVWDRCQVCGGDNSTCSPRKGSFTAGRAREYVTFLTVTPNLTSVYIANHRPLFTHL
100 110 120 130 140 150
600 610 620 630 640 650
pF1KE6 AVRIGGRYVVAGKMSISPNTTYPSLLEDGRVEYRVALTEDRLPRLEEIRIWGPLQEDADI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AVRIGGRYVVAGKMSISPNTTYPSLLEDGRVEYRVALTEDRLPRLEEIRIWGPLQEDADI
160 170 180 190 200 210
660 670 680 690 700 710
pF1KE6 QVYRRYGEEYGNLTRPDITFTYFQPKPRQAWVWAAVRGPCSVSCGAGLRWVNYSCLDQAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QVYRRYGEEYGNLTRPDITFTYFQPKPRQAWVWAAVRGPCSVSCGAGLRWVNYSCLDQAR
220 230 240 250 260 270
720 730 740 750 760 770
pF1KE6 KELVETVQCQGSQQPPAWPEACVLEPCPPYWAVGDFGPCSASCGGGLRERPVRCVEAQGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KELVETVQCQGSQQPPAWPEACVLEPCPPYWAVGDFGPCSASCGGGLRERPVRCVEAQGS
280 290 300 310 320 330
780 790 800 810 820 830
pF1KE6 LLKTLPPARCRAGAQQPAVALETCNPQPCPARWEVSEPSSCTSAGGAGLALENETCVPGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LLKTLPPARCRAGAQQPAVALETCNPQPCPARWEVSEPSSCTSAGGAGLALENETCVPGA
340 350 360 370 380 390
840 850 860 870 880 890
pF1KE6 DGLEAPVTEGPGSVDEKLPAPEPCVGMSCPPGWGHLDATSAGEKAPSPWGSIRTGAQAAH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DGLEAPVTEGPGSVDEKLPAPEPCVGMSCPPGWGHLDATSAGEKAPSPWGSIRTGAQAAH
400 410 420 430 440 450
900 910 920 930 940 950
pF1KE6 VWTPAAGSCSVSCGRGLMELRFLCMDSALRVPVQEELCGLASKPGSRREVCQAVPCPARW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VWTPAAGSCSVSCGRGLMELRFLCMDSALRVPVQEELCGLASKPGSRREVCQAVPCPARW
460 470 480 490 500 510
960 970 980 990 1000 1010
pF1KE6 QYKLAACSVSCGRGVVRRILYCARAHGEDDGEEILLDTQCQGLPRPEPQEACSLEPCPPR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QYKLAACSVSCGRGVVRRILYCARAHGEDDGEEILLDTQCQGLPRPEPQEACSLEPCPPR
520 530 540 550 560 570
1020 1030 1040 1050 1060 1070
pF1KE6 WKVMSLGPCSASCGLGTARRSVACVQLDQGQDVEVDEAACAALVRPEASVPCLIADCTYR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 WKVMSLGPCSASCGLGTARRSVACVQLDQGQDVEVDEAACAALVRPEASVPCLIADCTYR
580 590 600 610 620 630
1080 1090 1100 1110 1120 1130
pF1KE6 WHVGTWMECSVSCGDGIQRRRDTCLGPQAQAPVPADFCQHLPKPVTVRGCWAGPCVGQGT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 WHVGTWMECSVSCGDGIQRRRDTCLGPQAQAPVPADFCQHLPKPVTVRGCWAGPCVGQGT
640 650 660 670 680 690
1140 1150 1160 1170 1180 1190
pF1KE6 PSLVPHEEAAAPGRTTATPAGASLEWSQARGLLFSPAPQPRRLLPGPQENSVQSSACGRQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PSLVPHEEAAAPGRTTATPAGASLEWSQARGLLFSPAPQPRRLLPGPQENSVQSSACGRQ
700 710 720 730 740 750
1200 1210 1220 1230 1240 1250
pF1KE6 HLEPTGTIDMRGPGQADCAVAIGRPLGEVVTLRVLESSLNCSAGDMLLLWGRLTWRKMCR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HLEPTGTIDMRGPGQADCAVAIGRPLGEVVTLRVLESSLNCSAGDMLLLWGRLTWRKMCR
760 770 780 790 800 810
1260 1270 1280 1290 1300 1310
pF1KE6 KLLDMTFSSKTNTLVVRQRCGRPGGGVLLRYGSQLAPETFYRECDMQLFGPWGEIVSPSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KLLDMTFSSKTNTLVVRQRCGRPGGGVLLRYGSQLAPETFYRECDMQLFGPWGEIVSPSL
820 830 840 850 860 870
1320 1330 1340 1350 1360 1370
pF1KE6 SPATSNAGGCRLFINVAPHARIAIHALATNMGAGTEGANASYILIRDTHSLRTTAFHGQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SPATSNAGGCRLFINVAPHARIAIHALATNMGAGTEGANASYILIRDTHSLRTTAFHGQQ
880 890 900 910 920 930
1380 1390 1400 1410 1420
pF1KE6 VLYWESESSQAEMEFSEGFLKAQASLRGQYWTLQSWVPEMQDPQSWKGKEGT
::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VLYWESESSQAEMEFSEGFLKAQASLRGQYWTLQSWVPEMQDPQSWKGKEGT
940 950 960 970 980
>>XP_011516481 (OMIM: 274150,604134) PREDICTED: A disint (982 aa)
initn: 6126 init1: 6126 opt: 6126 Z-score: 4969.3 bits: 931.5 E(85289): 0
Smith-Waterman score: 6126; 99.7% identity (99.9% similar) in 863 aa overlap (565-1427:120-982)
540 550 560 570 580 590
pF1KE6 RMDSQQVWDRCQVCGGDNSTCSPRKGSFTAGRAREYVTFLTVTPNLTSVYIANHRPLFTH
:. .::::::::::::::::::::::::::
XP_011 HHEAWRQLPRWDPVYAKWPPGGRDPEPVCVGQLQEYVTFLTVTPNLTSVYIANHRPLFTH
90 100 110 120 130 140
600 610 620 630 640 650
pF1KE6 LAVRIGGRYVVAGKMSISPNTTYPSLLEDGRVEYRVALTEDRLPRLEEIRIWGPLQEDAD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LAVRIGGRYVVAGKMSISPNTTYPSLLEDGRVEYRVALTEDRLPRLEEIRIWGPLQEDAD
150 160 170 180 190 200
660 670 680 690 700 710
pF1KE6 IQVYRRYGEEYGNLTRPDITFTYFQPKPRQAWVWAAVRGPCSVSCGAGLRWVNYSCLDQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IQVYRRYGEEYGNLTRPDITFTYFQPKPRQAWVWAAVRGPCSVSCGAGLRWVNYSCLDQA
210 220 230 240 250 260
720 730 740 750 760 770
pF1KE6 RKELVETVQCQGSQQPPAWPEACVLEPCPPYWAVGDFGPCSASCGGGLRERPVRCVEAQG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RKELVETVQCQGSQQPPAWPEACVLEPCPPYWAVGDFGPCSASCGGGLRERPVRCVEAQG
270 280 290 300 310 320
780 790 800 810 820 830
pF1KE6 SLLKTLPPARCRAGAQQPAVALETCNPQPCPARWEVSEPSSCTSAGGAGLALENETCVPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SLLKTLPPARCRAGAQQPAVALETCNPQPCPARWEVSEPSSCTSAGGAGLALENETCVPG
330 340 350 360 370 380
840 850 860 870 880 890
pF1KE6 ADGLEAPVTEGPGSVDEKLPAPEPCVGMSCPPGWGHLDATSAGEKAPSPWGSIRTGAQAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ADGLEAPVTEGPGSVDEKLPAPEPCVGMSCPPGWGHLDATSAGEKAPSPWGSIRTGAQAA
390 400 410 420 430 440
900 910 920 930 940 950
pF1KE6 HVWTPAAGSCSVSCGRGLMELRFLCMDSALRVPVQEELCGLASKPGSRREVCQAVPCPAR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HVWTPAAGSCSVSCGRGLMELRFLCMDSALRVPVQEELCGLASKPGSRREVCQAVPCPAR
450 460 470 480 490 500
960 970 980 990 1000 1010
pF1KE6 WQYKLAACSVSCGRGVVRRILYCARAHGEDDGEEILLDTQCQGLPRPEPQEACSLEPCPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 WQYKLAACSVSCGRGVVRRILYCARAHGEDDGEEILLDTQCQGLPRPEPQEACSLEPCPP
510 520 530 540 550 560
1020 1030 1040 1050 1060 1070
pF1KE6 RWKVMSLGPCSASCGLGTARRSVACVQLDQGQDVEVDEAACAALVRPEASVPCLIADCTY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RWKVMSLGPCSASCGLGTARRSVACVQLDQGQDVEVDEAACAALVRPEASVPCLIADCTY
570 580 590 600 610 620
1080 1090 1100 1110 1120 1130
pF1KE6 RWHVGTWMECSVSCGDGIQRRRDTCLGPQAQAPVPADFCQHLPKPVTVRGCWAGPCVGQG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RWHVGTWMECSVSCGDGIQRRRDTCLGPQAQAPVPADFCQHLPKPVTVRGCWAGPCVGQG
630 640 650 660 670 680
1140 1150 1160 1170 1180 1190
pF1KE6 TPSLVPHEEAAAPGRTTATPAGASLEWSQARGLLFSPAPQPRRLLPGPQENSVQSSACGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TPSLVPHEEAAAPGRTTATPAGASLEWSQARGLLFSPAPQPRRLLPGPQENSVQSSACGR
690 700 710 720 730 740
1200 1210 1220 1230 1240 1250
pF1KE6 QHLEPTGTIDMRGPGQADCAVAIGRPLGEVVTLRVLESSLNCSAGDMLLLWGRLTWRKMC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QHLEPTGTIDMRGPGQADCAVAIGRPLGEVVTLRVLESSLNCSAGDMLLLWGRLTWRKMC
750 760 770 780 790 800
1260 1270 1280 1290 1300 1310
pF1KE6 RKLLDMTFSSKTNTLVVRQRCGRPGGGVLLRYGSQLAPETFYRECDMQLFGPWGEIVSPS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 RKLLDMTFSSKTNTLVVRQRCGRPGGGVLLRYGSQLAPETFYRECDMQLFGPWGEIVSPS
810 820 830 840 850 860
1320 1330 1340 1350 1360 1370
pF1KE6 LSPATSNAGGCRLFINVAPHARIAIHALATNMGAGTEGANASYILIRDTHSLRTTAFHGQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LSPATSNAGGCRLFINVAPHARIAIHALATNMGAGTEGANASYILIRDTHSLRTTAFHGQ
870 880 890 900 910 920
1380 1390 1400 1410 1420
pF1KE6 QVLYWESESSQAEMEFSEGFLKAQASLRGQYWTLQSWVPEMQDPQSWKGKEGT
:::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QVLYWESESSQAEMEFSEGFLKAQASLRGQYWTLQSWVPEMQDPQSWKGKEGT
930 940 950 960 970 980
>>NP_620595 (OMIM: 274150,604134) A disintegrin and meta (1340 aa)
initn: 6046 init1: 6046 opt: 6056 Z-score: 4910.9 bits: 921.1 E(85289): 0
Smith-Waterman score: 9400; 93.9% identity (93.9% similar) in 1427 aa overlap (1-1427:1-1340)
10 20 30 40 50 60
pF1KE6 MHQRHPRARCPPLCVAGILACGFLLGCWGPSHFQQSCLQALEPQAVSSYLSPGAPLKGRP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_620 MHQRHPRARCPPLCVAGILACGFLLGCWGPSHFQQSCLQALEPQAVSSYLSPGAPLKGRP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 PSPGFQRQRQRQRRAAGGILHLELLVAVGPDVFQAHQEDTERYVLTNLNIGAELLRDPSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_620 PSPGFQRQRQRQRRAAGGILHLELLVAVGPDVFQAHQEDTERYVLTNLNIGAELLRDPSL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 GAQFRVHLVKMVILTEPEGAPNITANLTSSLLSVCGWSQTINPEDDTDPGHADLVLYITR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_620 GAQFRVHLVKMVILTEPEGAPNITANLTSSLLSVCGWSQTINPEDDTDPGHADLVLYITR
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE6 FDLELPDGNRQVRGVTQLGGACSPTWSCLITEDTGFDLGVTIAHEIGHSFGLEHDGAPGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_620 FDLELPDGNRQVRGVTQLGGACSPTWSCLITEDTGFDLGVTIAHEIGHSFGLEHDGAPGS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE6 GCGPSGHVMASDGAAPRAGLAWSPCSRRQLLSLLSAGRARCVWDPPRPQPGSAGHPPDAQ
::::::::::::::::::::::::::::::::::::
NP_620 GCGPSGHVMASDGAAPRAGLAWSPCSRRQLLSLLSA------------------------
250 260 270
310 320 330 340 350 360
pF1KE6 PGLYYSANEQCRVAFGPKAVACTFAREHLDMCQALSCHTDPLDQSSCSRLLVPLLDGTEC
:::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_620 -------NEQCRVAFGPKAVACTFAREHLDMCQALSCHTDPLDQSSCSRLLVPLLDGTEC
280 290 300 310 320
370 380 390 400 410 420
pF1KE6 GVEKWCSKGRCRSLVELTPIAAVHGRWSSWGPRSPCSRSCGGGVVTRRRQCNNPRPAFGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_620 GVEKWCSKGRCRSLVELTPIAAVHGRWSSWGPRSPCSRSCGGGVVTRRRQCNNPRPAFGG
330 340 350 360 370 380
430 440 450 460 470 480
pF1KE6 RACVGADLQAEMCNTQACEKTQLEFMSQQCARTDGQPLRSSPGGASFYHWGAAVPHSQGD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_620 RACVGADLQAEMCNTQACEKTQLEFMSQQCARTDGQPLRSSPGGASFYHWGAAVPHSQGD
390 400 410 420 430 440
490 500 510 520 530 540
pF1KE6 ALCRHMCRAIGESFIMKRGDSFLDGTRCMPSGPREDGTLSLCVSGSCRTFGCDGRMDSQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_620 ALCRHMCRAIGESFIMKRGDSFLDGTRCMPSGPREDGTLSLCVSGSCRTFGCDGRMDSQQ
450 460 470 480 490 500
550 560 570 580 590 600
pF1KE6 VWDRCQVCGGDNSTCSPRKGSFTAGRAREYVTFLTVTPNLTSVYIANHRPLFTHLAVRIG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_620 VWDRCQVCGGDNSTCSPRKGSFTAGRAREYVTFLTVTPNLTSVYIANHRPLFTHLAVRIG
510 520 530 540 550 560
610 620 630 640 650 660
pF1KE6 GRYVVAGKMSISPNTTYPSLLEDGRVEYRVALTEDRLPRLEEIRIWGPLQEDADIQVYRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_620 GRYVVAGKMSISPNTTYPSLLEDGRVEYRVALTEDRLPRLEEIRIWGPLQEDADIQVYRR
570 580 590 600 610 620
670 680 690 700 710 720
pF1KE6 YGEEYGNLTRPDITFTYFQPKPRQAWVWAAVRGPCSVSCGAGLRWVNYSCLDQARKELVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_620 YGEEYGNLTRPDITFTYFQPKPRQAWVWAAVRGPCSVSCGAGLRWVNYSCLDQARKELVE
630 640 650 660 670 680
730 740 750 760 770 780
pF1KE6 TVQCQGSQQPPAWPEACVLEPCPPYWAVGDFGPCSASCGGGLRERPVRCVEAQGSLLKTL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_620 TVQCQGSQQPPAWPEACVLEPCPPYWAVGDFGPCSASCGGGLRERPVRCVEAQGSLLKTL
690 700 710 720 730 740
790 800 810 820 830 840
pF1KE6 PPARCRAGAQQPAVALETCNPQPCPARWEVSEPSSCTSAGGAGLALENETCVPGADGLEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_620 PPARCRAGAQQPAVALETCNPQPCPARWEVSEPSSCTSAGGAGLALENETCVPGADGLEA
750 760 770 780 790 800
850 860 870 880 890 900
pF1KE6 PVTEGPGSVDEKLPAPEPCVGMSCPPGWGHLDATSAGEKAPSPWGSIRTGAQAAHVWTPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_620 PVTEGPGSVDEKLPAPEPCVGMSCPPGWGHLDATSAGEKAPSPWGSIRTGAQAAHVWTPA
810 820 830 840 850 860
910 920 930 940 950 960
pF1KE6 AGSCSVSCGRGLMELRFLCMDSALRVPVQEELCGLASKPGSRREVCQAVPCPARWQYKLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_620 AGSCSVSCGRGLMELRFLCMDSALRVPVQEELCGLASKPGSRREVCQAVPCPARWQYKLA
870 880 890 900 910 920
970 980 990 1000 1010 1020
pF1KE6 ACSVSCGRGVVRRILYCARAHGEDDGEEILLDTQCQGLPRPEPQEACSLEPCPPRWKVMS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_620 ACSVSCGRGVVRRILYCARAHGEDDGEEILLDTQCQGLPRPEPQEACSLEPCPPRWKVMS
930 940 950 960 970 980
1030 1040 1050 1060 1070 1080
pF1KE6 LGPCSASCGLGTARRSVACVQLDQGQDVEVDEAACAALVRPEASVPCLIADCTYRWHVGT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_620 LGPCSASCGLGTARRSVACVQLDQGQDVEVDEAACAALVRPEASVPCLIADCTYRWHVGT
990 1000 1010 1020 1030 1040
1090 1100 1110 1120 1130 1140
pF1KE6 WMECSVSCGDGIQRRRDTCLGPQAQAPVPADFCQHLPKPVTVRGCWAGPCVGQGTPSLVP
::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_620 WMECSVSCGDGIQRRRDTCLGPQAQAPVPADFCQHLPKPVTVRGCWAGPCVGQG------
1050 1060 1070 1080 1090 1100
1150 1160 1170 1180 1190 1200
pF1KE6 HEEAAAPGRTTATPAGASLEWSQARGLLFSPAPQPRRLLPGPQENSVQSSACGRQHLEPT
::::::::::
NP_620 --------------------------------------------------ACGRQHLEPT
1110
1210 1220 1230 1240 1250 1260
pF1KE6 GTIDMRGPGQADCAVAIGRPLGEVVTLRVLESSLNCSAGDMLLLWGRLTWRKMCRKLLDM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_620 GTIDMRGPGQADCAVAIGRPLGEVVTLRVLESSLNCSAGDMLLLWGRLTWRKMCRKLLDM
1120 1130 1140 1150 1160 1170
1270 1280 1290 1300 1310 1320
pF1KE6 TFSSKTNTLVVRQRCGRPGGGVLLRYGSQLAPETFYRECDMQLFGPWGEIVSPSLSPATS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_620 TFSSKTNTLVVRQRCGRPGGGVLLRYGSQLAPETFYRECDMQLFGPWGEIVSPSLSPATS
1180 1190 1200 1210 1220 1230
1330 1340 1350 1360 1370 1380
pF1KE6 NAGGCRLFINVAPHARIAIHALATNMGAGTEGANASYILIRDTHSLRTTAFHGQQVLYWE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_620 NAGGCRLFINVAPHARIAIHALATNMGAGTEGANASYILIRDTHSLRTTAFHGQQVLYWE
1240 1250 1260 1270 1280 1290
1390 1400 1410 1420
pF1KE6 SESSQAEMEFSEGFLKAQASLRGQYWTLQSWVPEMQDPQSWKGKEGT
:::::::::::::::::::::::::::::::::::::::::::::::
NP_620 SESSQAEMEFSEGFLKAQASLRGQYWTLQSWVPEMQDPQSWKGKEGT
1300 1310 1320 1330 1340
>>XP_016869724 (OMIM: 274150,604134) PREDICTED: A disint (744 aa)
initn: 5337 init1: 5337 opt: 5337 Z-score: 4331.4 bits: 813.1 E(85289): 0
Smith-Waterman score: 5337; 100.0% identity (100.0% similar) in 744 aa overlap (1-744:1-744)
10 20 30 40 50 60
pF1KE6 MHQRHPRARCPPLCVAGILACGFLLGCWGPSHFQQSCLQALEPQAVSSYLSPGAPLKGRP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MHQRHPRARCPPLCVAGILACGFLLGCWGPSHFQQSCLQALEPQAVSSYLSPGAPLKGRP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 PSPGFQRQRQRQRRAAGGILHLELLVAVGPDVFQAHQEDTERYVLTNLNIGAELLRDPSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PSPGFQRQRQRQRRAAGGILHLELLVAVGPDVFQAHQEDTERYVLTNLNIGAELLRDPSL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 GAQFRVHLVKMVILTEPEGAPNITANLTSSLLSVCGWSQTINPEDDTDPGHADLVLYITR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GAQFRVHLVKMVILTEPEGAPNITANLTSSLLSVCGWSQTINPEDDTDPGHADLVLYITR
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE6 FDLELPDGNRQVRGVTQLGGACSPTWSCLITEDTGFDLGVTIAHEIGHSFGLEHDGAPGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FDLELPDGNRQVRGVTQLGGACSPTWSCLITEDTGFDLGVTIAHEIGHSFGLEHDGAPGS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE6 GCGPSGHVMASDGAAPRAGLAWSPCSRRQLLSLLSAGRARCVWDPPRPQPGSAGHPPDAQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GCGPSGHVMASDGAAPRAGLAWSPCSRRQLLSLLSAGRARCVWDPPRPQPGSAGHPPDAQ
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE6 PGLYYSANEQCRVAFGPKAVACTFAREHLDMCQALSCHTDPLDQSSCSRLLVPLLDGTEC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PGLYYSANEQCRVAFGPKAVACTFAREHLDMCQALSCHTDPLDQSSCSRLLVPLLDGTEC
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE6 GVEKWCSKGRCRSLVELTPIAAVHGRWSSWGPRSPCSRSCGGGVVTRRRQCNNPRPAFGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GVEKWCSKGRCRSLVELTPIAAVHGRWSSWGPRSPCSRSCGGGVVTRRRQCNNPRPAFGG
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE6 RACVGADLQAEMCNTQACEKTQLEFMSQQCARTDGQPLRSSPGGASFYHWGAAVPHSQGD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RACVGADLQAEMCNTQACEKTQLEFMSQQCARTDGQPLRSSPGGASFYHWGAAVPHSQGD
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE6 ALCRHMCRAIGESFIMKRGDSFLDGTRCMPSGPREDGTLSLCVSGSCRTFGCDGRMDSQQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ALCRHMCRAIGESFIMKRGDSFLDGTRCMPSGPREDGTLSLCVSGSCRTFGCDGRMDSQQ
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE6 VWDRCQVCGGDNSTCSPRKGSFTAGRAREYVTFLTVTPNLTSVYIANHRPLFTHLAVRIG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VWDRCQVCGGDNSTCSPRKGSFTAGRAREYVTFLTVTPNLTSVYIANHRPLFTHLAVRIG
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE6 GRYVVAGKMSISPNTTYPSLLEDGRVEYRVALTEDRLPRLEEIRIWGPLQEDADIQVYRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GRYVVAGKMSISPNTTYPSLLEDGRVEYRVALTEDRLPRLEEIRIWGPLQEDADIQVYRR
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE6 YGEEYGNLTRPDITFTYFQPKPRQAWVWAAVRGPCSVSCGAGLRWVNYSCLDQARKELVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YGEEYGNLTRPDITFTYFQPKPRQAWVWAAVRGPCSVSCGAGLRWVNYSCLDQARKELVE
670 680 690 700 710 720
730 740 750 760 770 780
pF1KE6 TVQCQGSQQPPAWPEACVLEPCPPYWAVGDFGPCSASCGGGLRERPVRCVEAQGSLLKTL
::::::::::::::::::::::::
XP_016 TVQCQGSQQPPAWPEACVLEPCPP
730 740
1427 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Nov 8 15:55:37 2016 done: Tue Nov 8 15:55:39 2016
Total Scan time: 15.700 Total Display time: 0.630
Function used was FASTA [36.3.4 Apr, 2011]