Result of FASTA (omim) for
pFN21AE6740
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE6740, 776 aa
1>>>pF1KE6740 776 - 776 aa - 776 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 7.2557+/-0.000373; mu= 13.1407+/- 0.023
mean_var=147.2036+/-29.453, 0's: 0 Z-trim(117.4): 39 B-trim: 45 in 1/55
Lambda= 0.105710
statistics sampled from 29351 (29390) to 29351 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.688), E-opt: 0.2 (0.345), width: 16
Scan time: 7.730
The best scores are: opt bits E(85289)
NP_000471 (OMIM: 102772,612874) AMP deaminase 3 is ( 776) 5238 811.0 0
NP_001020561 (OMIM: 102772,612874) AMP deaminase 3 ( 774) 5197 804.8 0
NP_001020560 (OMIM: 102772,612874) AMP deaminase 3 ( 767) 5184 802.8 0
NP_001165901 (OMIM: 102772,612874) AMP deaminase 3 ( 767) 5184 802.8 0
NP_001165902 (OMIM: 102772,612874) AMP deaminase 3 ( 608) 4150 645.0 2.7e-184
NP_001166097 (OMIM: 102770,615511) AMP deaminase 1 ( 776) 2991 468.4 5.3e-131
NP_000027 (OMIM: 102770,615511) AMP deaminase 1 is ( 780) 2991 468.4 5.3e-131
NP_631895 (OMIM: 102771,615686,615809) AMP deamina ( 798) 2510 395.0 6.5e-109
NP_001244289 (OMIM: 102771,615686,615809) AMP deam ( 879) 2510 395.0 7e-109
NP_004028 (OMIM: 102771,615686,615809) AMP deamina ( 879) 2510 395.0 7e-109
NP_001244290 (OMIM: 102771,615686,615809) AMP deam ( 761) 2494 392.5 3.4e-108
NP_001295099 (OMIM: 102771,615686,615809) AMP deam ( 804) 2477 390.0 2.1e-107
NP_981949 (OMIM: 102771,615686,615809) AMP deamina ( 760) 2476 389.8 2.3e-107
>>NP_000471 (OMIM: 102772,612874) AMP deaminase 3 isofor (776 aa)
initn: 5238 init1: 5238 opt: 5238 Z-score: 4324.9 bits: 811.0 E(85289): 0
Smith-Waterman score: 5238; 100.0% identity (100.0% similar) in 776 aa overlap (1-776:1-776)
10 20 30 40 50 60
pF1KE6 MALSSEPAEMPRQFPKLNISEVDEQVRLLAEKVFAKVLREEDSKDALSLFTVPEDCPIGQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 MALSSEPAEMPRQFPKLNISEVDEQVRLLAEKVFAKVLREEDSKDALSLFTVPEDCPIGQ
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 KEAKERELQKELAEQKSVETAKRKKSFKMIRSQSLSLQMPPQQDWKGPPAASPAMSPTTP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 KEAKERELQKELAEQKSVETAKRKKSFKMIRSQSLSLQMPPQQDWKGPPAASPAMSPTTP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 VVTGATSLPTPAPYAMPEFQRVTISGDYCAGITLEDYEQAAKSLAKALMIREKYARLAYH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 VVTGATSLPTPAPYAMPEFQRVTISGDYCAGITLEDYEQAAKSLAKALMIREKYARLAYH
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE6 RFPRITSQYLGHPRADTAPPEEGLPDFHPPPLPQEDPYCLDDAPPNLDYLVHMQGGILFV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 RFPRITSQYLGHPRADTAPPEEGLPDFHPPPLPQEDPYCLDDAPPNLDYLVHMQGGILFV
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE6 YDNKKMLEHQEPHSLPYPDLETYTVDMSHILALITDGPTKTYCHRRLNFLESKFSLHEML
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 YDNKKMLEHQEPHSLPYPDLETYTVDMSHILALITDGPTKTYCHRRLNFLESKFSLHEML
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE6 NEMSEFKELKSNPHRDFYNVRKVDTHIHAAACMNQKHLLRFIKHTYQTEPDRTVAEKRGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 NEMSEFKELKSNPHRDFYNVRKVDTHIHAAACMNQKHLLRFIKHTYQTEPDRTVAEKRGR
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE6 KITLRQVFDGLHMDPYDLTVDSLDVHAGRQTFHRFDKFNSKYNPVGASELRDLYLKTENY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 KITLRQVFDGLHMDPYDLTVDSLDVHAGRQTFHRFDKFNSKYNPVGASELRDLYLKTENY
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE6 LGGEYFARMVKEVARELEESKYQYSEPRLSIYGRSPEEWPNLAYWFIQHKVYSPNMRWII
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 LGGEYFARMVKEVARELEESKYQYSEPRLSIYGRSPEEWPNLAYWFIQHKVYSPNMRWII
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE6 QVPRIYDIFRSKKLLPNFGKMLENIFLPLFKATINPQDHRELHLFLKYVTGFDSVDDESK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 QVPRIYDIFRSKKLLPNFGKMLENIFLPLFKATINPQDHRELHLFLKYVTGFDSVDDESK
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE6 HSDHMFSDKSPNPDVWTSEQNPPYSYYLYYMYANIMVLNNLRRERGLSTFLFRPHCGEAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 HSDHMFSDKSPNPDVWTSEQNPPYSYYLYYMYANIMVLNNLRRERGLSTFLFRPHCGEAG
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE6 SITHLVSAFLTADNISHGLLLKKSPVLQYLYYLAQIPIAMSPLSNNSLFLEYSKNPLREF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 SITHLVSAFLTADNISHGLLLKKSPVLQYLYYLAQIPIAMSPLSNNSLFLEYSKNPLREF
610 620 630 640 650 660
670 680 690 700 710 720
pF1KE6 LHKGLHVSLSTDDPMQFHYTKEALMEEYAIAAQVWKLSTCDLCEIARNSVLQSGLSHQEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 LHKGLHVSLSTDDPMQFHYTKEALMEEYAIAAQVWKLSTCDLCEIARNSVLQSGLSHQEK
670 680 690 700 710 720
730 740 750 760 770
pF1KE6 QKFLGQNYYKEGPEGNDIRKTNVAQIRMAFRYETLCNELSFLSDAMKSEEITALTN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 QKFLGQNYYKEGPEGNDIRKTNVAQIRMAFRYETLCNELSFLSDAMKSEEITALTN
730 740 750 760 770
>>NP_001020561 (OMIM: 102772,612874) AMP deaminase 3 iso (774 aa)
initn: 5195 init1: 5195 opt: 5197 Z-score: 4291.1 bits: 804.8 E(85289): 0
Smith-Waterman score: 5197; 99.7% identity (99.7% similar) in 773 aa overlap (6-776:2-774)
10 20 30 40 50
pF1KE6 MALSSEP--AEMPRQFPKLNISEVDEQVRLLAEKVFAKVLREEDSKDALSLFTVPEDCPI
:: :::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MEPGSAEMPRQFPKLNISEVDEQVRLLAEKVFAKVLREEDSKDALSLFTVPEDCPI
10 20 30 40 50
60 70 80 90 100 110
pF1KE6 GQKEAKERELQKELAEQKSVETAKRKKSFKMIRSQSLSLQMPPQQDWKGPPAASPAMSPT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GQKEAKERELQKELAEQKSVETAKRKKSFKMIRSQSLSLQMPPQQDWKGPPAASPAMSPT
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE6 TPVVTGATSLPTPAPYAMPEFQRVTISGDYCAGITLEDYEQAAKSLAKALMIREKYARLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TPVVTGATSLPTPAPYAMPEFQRVTISGDYCAGITLEDYEQAAKSLAKALMIREKYARLA
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE6 YHRFPRITSQYLGHPRADTAPPEEGLPDFHPPPLPQEDPYCLDDAPPNLDYLVHMQGGIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YHRFPRITSQYLGHPRADTAPPEEGLPDFHPPPLPQEDPYCLDDAPPNLDYLVHMQGGIL
180 190 200 210 220 230
240 250 260 270 280 290
pF1KE6 FVYDNKKMLEHQEPHSLPYPDLETYTVDMSHILALITDGPTKTYCHRRLNFLESKFSLHE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FVYDNKKMLEHQEPHSLPYPDLETYTVDMSHILALITDGPTKTYCHRRLNFLESKFSLHE
240 250 260 270 280 290
300 310 320 330 340 350
pF1KE6 MLNEMSEFKELKSNPHRDFYNVRKVDTHIHAAACMNQKHLLRFIKHTYQTEPDRTVAEKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MLNEMSEFKELKSNPHRDFYNVRKVDTHIHAAACMNQKHLLRFIKHTYQTEPDRTVAEKR
300 310 320 330 340 350
360 370 380 390 400 410
pF1KE6 GRKITLRQVFDGLHMDPYDLTVDSLDVHAGRQTFHRFDKFNSKYNPVGASELRDLYLKTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GRKITLRQVFDGLHMDPYDLTVDSLDVHAGRQTFHRFDKFNSKYNPVGASELRDLYLKTE
360 370 380 390 400 410
420 430 440 450 460 470
pF1KE6 NYLGGEYFARMVKEVARELEESKYQYSEPRLSIYGRSPEEWPNLAYWFIQHKVYSPNMRW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NYLGGEYFARMVKEVARELEESKYQYSEPRLSIYGRSPEEWPNLAYWFIQHKVYSPNMRW
420 430 440 450 460 470
480 490 500 510 520 530
pF1KE6 IIQVPRIYDIFRSKKLLPNFGKMLENIFLPLFKATINPQDHRELHLFLKYVTGFDSVDDE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IIQVPRIYDIFRSKKLLPNFGKMLENIFLPLFKATINPQDHRELHLFLKYVTGFDSVDDE
480 490 500 510 520 530
540 550 560 570 580 590
pF1KE6 SKHSDHMFSDKSPNPDVWTSEQNPPYSYYLYYMYANIMVLNNLRRERGLSTFLFRPHCGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SKHSDHMFSDKSPNPDVWTSEQNPPYSYYLYYMYANIMVLNNLRRERGLSTFLFRPHCGE
540 550 560 570 580 590
600 610 620 630 640 650
pF1KE6 AGSITHLVSAFLTADNISHGLLLKKSPVLQYLYYLAQIPIAMSPLSNNSLFLEYSKNPLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AGSITHLVSAFLTADNISHGLLLKKSPVLQYLYYLAQIPIAMSPLSNNSLFLEYSKNPLR
600 610 620 630 640 650
660 670 680 690 700 710
pF1KE6 EFLHKGLHVSLSTDDPMQFHYTKEALMEEYAIAAQVWKLSTCDLCEIARNSVLQSGLSHQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EFLHKGLHVSLSTDDPMQFHYTKEALMEEYAIAAQVWKLSTCDLCEIARNSVLQSGLSHQ
660 670 680 690 700 710
720 730 740 750 760 770
pF1KE6 EKQKFLGQNYYKEGPEGNDIRKTNVAQIRMAFRYETLCNELSFLSDAMKSEEITALTN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EKQKFLGQNYYKEGPEGNDIRKTNVAQIRMAFRYETLCNELSFLSDAMKSEEITALTN
720 730 740 750 760 770
>>NP_001020560 (OMIM: 102772,612874) AMP deaminase 3 iso (767 aa)
initn: 5184 init1: 5184 opt: 5184 Z-score: 4280.5 bits: 802.8 E(85289): 0
Smith-Waterman score: 5184; 100.0% identity (100.0% similar) in 767 aa overlap (10-776:1-767)
10 20 30 40 50 60
pF1KE6 MALSSEPAEMPRQFPKLNISEVDEQVRLLAEKVFAKVLREEDSKDALSLFTVPEDCPIGQ
:::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MPRQFPKLNISEVDEQVRLLAEKVFAKVLREEDSKDALSLFTVPEDCPIGQ
10 20 30 40 50
70 80 90 100 110 120
pF1KE6 KEAKERELQKELAEQKSVETAKRKKSFKMIRSQSLSLQMPPQQDWKGPPAASPAMSPTTP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KEAKERELQKELAEQKSVETAKRKKSFKMIRSQSLSLQMPPQQDWKGPPAASPAMSPTTP
60 70 80 90 100 110
130 140 150 160 170 180
pF1KE6 VVTGATSLPTPAPYAMPEFQRVTISGDYCAGITLEDYEQAAKSLAKALMIREKYARLAYH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VVTGATSLPTPAPYAMPEFQRVTISGDYCAGITLEDYEQAAKSLAKALMIREKYARLAYH
120 130 140 150 160 170
190 200 210 220 230 240
pF1KE6 RFPRITSQYLGHPRADTAPPEEGLPDFHPPPLPQEDPYCLDDAPPNLDYLVHMQGGILFV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RFPRITSQYLGHPRADTAPPEEGLPDFHPPPLPQEDPYCLDDAPPNLDYLVHMQGGILFV
180 190 200 210 220 230
250 260 270 280 290 300
pF1KE6 YDNKKMLEHQEPHSLPYPDLETYTVDMSHILALITDGPTKTYCHRRLNFLESKFSLHEML
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YDNKKMLEHQEPHSLPYPDLETYTVDMSHILALITDGPTKTYCHRRLNFLESKFSLHEML
240 250 260 270 280 290
310 320 330 340 350 360
pF1KE6 NEMSEFKELKSNPHRDFYNVRKVDTHIHAAACMNQKHLLRFIKHTYQTEPDRTVAEKRGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NEMSEFKELKSNPHRDFYNVRKVDTHIHAAACMNQKHLLRFIKHTYQTEPDRTVAEKRGR
300 310 320 330 340 350
370 380 390 400 410 420
pF1KE6 KITLRQVFDGLHMDPYDLTVDSLDVHAGRQTFHRFDKFNSKYNPVGASELRDLYLKTENY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KITLRQVFDGLHMDPYDLTVDSLDVHAGRQTFHRFDKFNSKYNPVGASELRDLYLKTENY
360 370 380 390 400 410
430 440 450 460 470 480
pF1KE6 LGGEYFARMVKEVARELEESKYQYSEPRLSIYGRSPEEWPNLAYWFIQHKVYSPNMRWII
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LGGEYFARMVKEVARELEESKYQYSEPRLSIYGRSPEEWPNLAYWFIQHKVYSPNMRWII
420 430 440 450 460 470
490 500 510 520 530 540
pF1KE6 QVPRIYDIFRSKKLLPNFGKMLENIFLPLFKATINPQDHRELHLFLKYVTGFDSVDDESK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QVPRIYDIFRSKKLLPNFGKMLENIFLPLFKATINPQDHRELHLFLKYVTGFDSVDDESK
480 490 500 510 520 530
550 560 570 580 590 600
pF1KE6 HSDHMFSDKSPNPDVWTSEQNPPYSYYLYYMYANIMVLNNLRRERGLSTFLFRPHCGEAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HSDHMFSDKSPNPDVWTSEQNPPYSYYLYYMYANIMVLNNLRRERGLSTFLFRPHCGEAG
540 550 560 570 580 590
610 620 630 640 650 660
pF1KE6 SITHLVSAFLTADNISHGLLLKKSPVLQYLYYLAQIPIAMSPLSNNSLFLEYSKNPLREF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SITHLVSAFLTADNISHGLLLKKSPVLQYLYYLAQIPIAMSPLSNNSLFLEYSKNPLREF
600 610 620 630 640 650
670 680 690 700 710 720
pF1KE6 LHKGLHVSLSTDDPMQFHYTKEALMEEYAIAAQVWKLSTCDLCEIARNSVLQSGLSHQEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LHKGLHVSLSTDDPMQFHYTKEALMEEYAIAAQVWKLSTCDLCEIARNSVLQSGLSHQEK
660 670 680 690 700 710
730 740 750 760 770
pF1KE6 QKFLGQNYYKEGPEGNDIRKTNVAQIRMAFRYETLCNELSFLSDAMKSEEITALTN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QKFLGQNYYKEGPEGNDIRKTNVAQIRMAFRYETLCNELSFLSDAMKSEEITALTN
720 730 740 750 760
>>NP_001165901 (OMIM: 102772,612874) AMP deaminase 3 iso (767 aa)
initn: 5184 init1: 5184 opt: 5184 Z-score: 4280.5 bits: 802.8 E(85289): 0
Smith-Waterman score: 5184; 100.0% identity (100.0% similar) in 767 aa overlap (10-776:1-767)
10 20 30 40 50 60
pF1KE6 MALSSEPAEMPRQFPKLNISEVDEQVRLLAEKVFAKVLREEDSKDALSLFTVPEDCPIGQ
:::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MPRQFPKLNISEVDEQVRLLAEKVFAKVLREEDSKDALSLFTVPEDCPIGQ
10 20 30 40 50
70 80 90 100 110 120
pF1KE6 KEAKERELQKELAEQKSVETAKRKKSFKMIRSQSLSLQMPPQQDWKGPPAASPAMSPTTP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KEAKERELQKELAEQKSVETAKRKKSFKMIRSQSLSLQMPPQQDWKGPPAASPAMSPTTP
60 70 80 90 100 110
130 140 150 160 170 180
pF1KE6 VVTGATSLPTPAPYAMPEFQRVTISGDYCAGITLEDYEQAAKSLAKALMIREKYARLAYH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VVTGATSLPTPAPYAMPEFQRVTISGDYCAGITLEDYEQAAKSLAKALMIREKYARLAYH
120 130 140 150 160 170
190 200 210 220 230 240
pF1KE6 RFPRITSQYLGHPRADTAPPEEGLPDFHPPPLPQEDPYCLDDAPPNLDYLVHMQGGILFV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RFPRITSQYLGHPRADTAPPEEGLPDFHPPPLPQEDPYCLDDAPPNLDYLVHMQGGILFV
180 190 200 210 220 230
250 260 270 280 290 300
pF1KE6 YDNKKMLEHQEPHSLPYPDLETYTVDMSHILALITDGPTKTYCHRRLNFLESKFSLHEML
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YDNKKMLEHQEPHSLPYPDLETYTVDMSHILALITDGPTKTYCHRRLNFLESKFSLHEML
240 250 260 270 280 290
310 320 330 340 350 360
pF1KE6 NEMSEFKELKSNPHRDFYNVRKVDTHIHAAACMNQKHLLRFIKHTYQTEPDRTVAEKRGR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NEMSEFKELKSNPHRDFYNVRKVDTHIHAAACMNQKHLLRFIKHTYQTEPDRTVAEKRGR
300 310 320 330 340 350
370 380 390 400 410 420
pF1KE6 KITLRQVFDGLHMDPYDLTVDSLDVHAGRQTFHRFDKFNSKYNPVGASELRDLYLKTENY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KITLRQVFDGLHMDPYDLTVDSLDVHAGRQTFHRFDKFNSKYNPVGASELRDLYLKTENY
360 370 380 390 400 410
430 440 450 460 470 480
pF1KE6 LGGEYFARMVKEVARELEESKYQYSEPRLSIYGRSPEEWPNLAYWFIQHKVYSPNMRWII
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LGGEYFARMVKEVARELEESKYQYSEPRLSIYGRSPEEWPNLAYWFIQHKVYSPNMRWII
420 430 440 450 460 470
490 500 510 520 530 540
pF1KE6 QVPRIYDIFRSKKLLPNFGKMLENIFLPLFKATINPQDHRELHLFLKYVTGFDSVDDESK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QVPRIYDIFRSKKLLPNFGKMLENIFLPLFKATINPQDHRELHLFLKYVTGFDSVDDESK
480 490 500 510 520 530
550 560 570 580 590 600
pF1KE6 HSDHMFSDKSPNPDVWTSEQNPPYSYYLYYMYANIMVLNNLRRERGLSTFLFRPHCGEAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HSDHMFSDKSPNPDVWTSEQNPPYSYYLYYMYANIMVLNNLRRERGLSTFLFRPHCGEAG
540 550 560 570 580 590
610 620 630 640 650 660
pF1KE6 SITHLVSAFLTADNISHGLLLKKSPVLQYLYYLAQIPIAMSPLSNNSLFLEYSKNPLREF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SITHLVSAFLTADNISHGLLLKKSPVLQYLYYLAQIPIAMSPLSNNSLFLEYSKNPLREF
600 610 620 630 640 650
670 680 690 700 710 720
pF1KE6 LHKGLHVSLSTDDPMQFHYTKEALMEEYAIAAQVWKLSTCDLCEIARNSVLQSGLSHQEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LHKGLHVSLSTDDPMQFHYTKEALMEEYAIAAQVWKLSTCDLCEIARNSVLQSGLSHQEK
660 670 680 690 700 710
730 740 750 760 770
pF1KE6 QKFLGQNYYKEGPEGNDIRKTNVAQIRMAFRYETLCNELSFLSDAMKSEEITALTN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QKFLGQNYYKEGPEGNDIRKTNVAQIRMAFRYETLCNELSFLSDAMKSEEITALTN
720 730 740 750 760
>>NP_001165902 (OMIM: 102772,612874) AMP deaminase 3 iso (608 aa)
initn: 4150 init1: 4150 opt: 4150 Z-score: 3429.6 bits: 645.0 E(85289): 2.7e-184
Smith-Waterman score: 4150; 100.0% identity (100.0% similar) in 608 aa overlap (169-776:1-608)
140 150 160 170 180 190
pF1KE6 FQRVTISGDYCAGITLEDYEQAAKSLAKALMIREKYARLAYHRFPRITSQYLGHPRADTA
::::::::::::::::::::::::::::::
NP_001 MIREKYARLAYHRFPRITSQYLGHPRADTA
10 20 30
200 210 220 230 240 250
pF1KE6 PPEEGLPDFHPPPLPQEDPYCLDDAPPNLDYLVHMQGGILFVYDNKKMLEHQEPHSLPYP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PPEEGLPDFHPPPLPQEDPYCLDDAPPNLDYLVHMQGGILFVYDNKKMLEHQEPHSLPYP
40 50 60 70 80 90
260 270 280 290 300 310
pF1KE6 DLETYTVDMSHILALITDGPTKTYCHRRLNFLESKFSLHEMLNEMSEFKELKSNPHRDFY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DLETYTVDMSHILALITDGPTKTYCHRRLNFLESKFSLHEMLNEMSEFKELKSNPHRDFY
100 110 120 130 140 150
320 330 340 350 360 370
pF1KE6 NVRKVDTHIHAAACMNQKHLLRFIKHTYQTEPDRTVAEKRGRKITLRQVFDGLHMDPYDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NVRKVDTHIHAAACMNQKHLLRFIKHTYQTEPDRTVAEKRGRKITLRQVFDGLHMDPYDL
160 170 180 190 200 210
380 390 400 410 420 430
pF1KE6 TVDSLDVHAGRQTFHRFDKFNSKYNPVGASELRDLYLKTENYLGGEYFARMVKEVARELE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TVDSLDVHAGRQTFHRFDKFNSKYNPVGASELRDLYLKTENYLGGEYFARMVKEVARELE
220 230 240 250 260 270
440 450 460 470 480 490
pF1KE6 ESKYQYSEPRLSIYGRSPEEWPNLAYWFIQHKVYSPNMRWIIQVPRIYDIFRSKKLLPNF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ESKYQYSEPRLSIYGRSPEEWPNLAYWFIQHKVYSPNMRWIIQVPRIYDIFRSKKLLPNF
280 290 300 310 320 330
500 510 520 530 540 550
pF1KE6 GKMLENIFLPLFKATINPQDHRELHLFLKYVTGFDSVDDESKHSDHMFSDKSPNPDVWTS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GKMLENIFLPLFKATINPQDHRELHLFLKYVTGFDSVDDESKHSDHMFSDKSPNPDVWTS
340 350 360 370 380 390
560 570 580 590 600 610
pF1KE6 EQNPPYSYYLYYMYANIMVLNNLRRERGLSTFLFRPHCGEAGSITHLVSAFLTADNISHG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EQNPPYSYYLYYMYANIMVLNNLRRERGLSTFLFRPHCGEAGSITHLVSAFLTADNISHG
400 410 420 430 440 450
620 630 640 650 660 670
pF1KE6 LLLKKSPVLQYLYYLAQIPIAMSPLSNNSLFLEYSKNPLREFLHKGLHVSLSTDDPMQFH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LLLKKSPVLQYLYYLAQIPIAMSPLSNNSLFLEYSKNPLREFLHKGLHVSLSTDDPMQFH
460 470 480 490 500 510
680 690 700 710 720 730
pF1KE6 YTKEALMEEYAIAAQVWKLSTCDLCEIARNSVLQSGLSHQEKQKFLGQNYYKEGPEGNDI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YTKEALMEEYAIAAQVWKLSTCDLCEIARNSVLQSGLSHQEKQKFLGQNYYKEGPEGNDI
520 530 540 550 560 570
740 750 760 770
pF1KE6 RKTNVAQIRMAFRYETLCNELSFLSDAMKSEEITALTN
::::::::::::::::::::::::::::::::::::::
NP_001 RKTNVAQIRMAFRYETLCNELSFLSDAMKSEEITALTN
580 590 600
>>NP_001166097 (OMIM: 102770,615511) AMP deaminase 1 iso (776 aa)
initn: 3107 init1: 2779 opt: 2991 Z-score: 2472.9 bits: 468.4 E(85289): 5.3e-131
Smith-Waterman score: 3114; 60.2% identity (83.2% similar) in 757 aa overlap (15-770:35-776)
10 20 30 40
pF1KE6 MALSSEPAEMPRQFPKLNISEVDEQVRLLAEKVFAKVLREEDSK
: ... :.:. .: .::::::. ...: ..
NP_001 IFYSVSQSPHSLLSLLFYCAILESRISATMPLFKLPEIDDAMRNFAEKVFASEVKDEGGR
10 20 30 40 50 60
50 60 70 80 90 100
pF1KE6 DALSLFTVPEDCPIGQKEAKERELQKELAEQKSVETAKRKKSFKMIRSQSLSLQMPPQQD
. .: : : : :::...: . . .. : . . :.: :.::: :. .. .::. .
NP_001 QEISPFDVDEICPISHHEMQAHIFHLE-TLSTSTE-ARRKKRFQGRKTVNLSIPLS----
70 80 90 100 110
110 120 130 140 150 160
pF1KE6 WKGPPAASPAMSPTTPVVTGATSLPTPAPYAMPEFQRVTISGDYCAGITLEDYEQAAKSL
..: .: ... .:. ..:.:::: :.::: .:.:.::.: . :.:
NP_001 ----ETSSTKLSHIDEYISS-----SPTYQTVPDFQRVQITGDYASGVTVEDFEIVCKGL
120 130 140 150 160
170 180 190 200 210 220
pF1KE6 AKALMIREKYARLAYHRFPRITSQYLGHPRADTAPPEEGL-PDFHPPPLPQEDPYCLDDA
.:: ::::: . ...:::. :.:: . ... .:.. : : :: :::. :.
NP_001 YRALCIREKYMQKSFQRFPKTPSKYLRNIDGEAWVANESFYPVFTPPVKKGEDPFRTDNL
170 180 190 200 210 220
230 240 250 260 270 280
pF1KE6 PPNLDYLVHMQGGILFVYDNKKMLEHQEPHSLPYPDLETYTVDMSHILALITDGPTKTYC
: :: : ..:. :...:: :. . ..::. ::::.:.:. ::. .::::..::.:::
NP_001 PENLGYHLKMKDGVVYVYPNEAAVSKDEPKPLPYPNLDTFLDDMNFLLALIAQGPVKTYT
230 240 250 260 270 280
290 300 310 320 330 340
pF1KE6 HRRLNFLESKFSLHEMLNEMSEFKELKSNPHRDFYNVRKVDTHIHAAACMNQKHLLRFIK
::::.:: :::..:.:::::.:.::::.:::::::: :::::::::::::::::::::::
NP_001 HRRLKFLSSKFQVHQMLNEMDELKELKNNPHRDFYNCRKVDTHIHAAACMNQKHLLRFIK
290 300 310 320 330 340
350 360 370 380 390 400
pF1KE6 HTYQTEPDRTVAEKRGRKITLRQVFDGLHMDPYDLTVDSLDVHAGRQTFHRFDKFNSKYN
..:: . ::.: . ...::...: :.: ::::::::::::::::::.::::::.:::
NP_001 KSYQIDADRVVYSTKEKNLTLKELFAKLKMHPYDLTVDSLDVHAGRQTFQRFDKFNDKYN
350 360 370 380 390 400
410 420 430 440 450 460
pF1KE6 PVGASELRDLYLKTENYLGGEYFARMVKEVARELEESKYQYSEPRLSIYGRSPEEWPNLA
::::::::::::::.::..::::: ..:::. .: :.:::..:::::::::::.:: .:.
NP_001 PVGASELRDLYLKTDNYINGEYFATIIKEVGADLVEAKYQHAEPRLSIYGRSPDEWSKLS
410 420 430 440 450 460
470 480 490 500 510 520
pF1KE6 YWFIQHKVYSPNMRWIIQVPRIYDIFRSKKLLPNFGKMLENIFLPLFKATINPQDHRELH
::. .... ::: :.::::::::.::::..::.:::::::::.:.:.:::::: ::
NP_001 SWFVCNRIHCPNMTWMIQVPRIYDVFRSKNFLPHFGKMLENIFMPVFEATINPQADPELS
470 480 490 500 510 520
530 540 550 560 570 580
pF1KE6 LFLKYVTGFDSVDDESKHSDHMFSDKSPNPDVWTSEQNPPYSYYLYYMYANIMVLNNLRR
.:::..::::::::::::: ::::.:::.:. :: :.:: :.:: :::::::::::.::.
NP_001 VFLKHITGFDSVDDESKHSGHMFSSKSPKPQEWTLEKNPSYTYYAYYMYANIMVLNSLRK
530 540 550 560 570 580
590 600 610 620 630 640
pF1KE6 ERGLSTFLFRPHCGEAGSITHLVSAFLTADNISHGLLLKKSPVLQYLYYLAQIPIAMSPL
:::..::::::::::::..:::..::. ::.::::: ::::::::::..:::::::::::
NP_001 ERGMNTFLFRPHCGEAGALTHLMTAFMIADDISHGLNLKKSPVLQYLFFLAQIPIAMSPL
590 600 610 620 630 640
650 660 670 680 690 700
pF1KE6 SNNSLFLEYSKNPLREFLHKGLHVSLSTDDPMQFHYTKEALMEEYAIAAQVWKLSTCDLC
:::::::::.:::. .::.::: .:::::::::::.::: :::::::::::.::::::.:
NP_001 SNNSLFLEYAKNPFLDFLQKGLMISLSTDDPMQFHFTKEPLMEEYAIAAQVFKLSTCDMC
650 660 670 680 690 700
710 720 730 740 750 760
pF1KE6 EIARNSVLQSGLSHQEKQKFLGQNYYKEGPEGNDIRKTNVAQIRMAFRYETLCNELSFLS
:.::::::: :.::.:: ::::.:: .::: :::::.:::::::::.:::: : ::....
NP_001 EVARNSVLQCGISHEEKVKFLGDNYLEEGPAGNDIRRTNVAQIRMAYRYETWCYELNLIA
710 720 730 740 750 760
770
pF1KE6 DAMKSEEITALTN
...:: :
NP_001 EGLKSTE
770
>>NP_000027 (OMIM: 102770,615511) AMP deaminase 1 isofor (780 aa)
initn: 3129 init1: 2779 opt: 2991 Z-score: 2472.9 bits: 468.4 E(85289): 5.3e-131
Smith-Waterman score: 3104; 60.0% identity (83.1% similar) in 765 aa overlap (8-770:32-780)
10 20 30
pF1KE6 MALSSEPAEMPR-QFPKLNISEVDEQVRLLAEKVFAK
: :: ..: . ...:. .: .::::::.
NP_000 NVRIFYSVSQSPHSLLSLLFYCAILESRISATMPLFKLPAEE-KQIDDAMRNFAEKVFAS
10 20 30 40 50 60
40 50 60 70 80 90
pF1KE6 VLREEDSKDALSLFTVPEDCPIGQKEAKERELQKELAEQKSVETAKRKKSFKMIRSQSLS
...: ... .: : : : :::...: . . .. : . . :.: :.::: :. .. .::
NP_000 EVKDEGGRQEISPFDVDEICPISHHEMQAHIFHLE-TLSTSTE-ARRKKRFQGRKTVNLS
70 80 90 100 110
100 110 120 130 140 150
pF1KE6 LQMPPQQDWKGPPAASPAMSPTTPVVTGATSLPTPAPYAMPEFQRVTISGDYCAGITLED
. : .. ..: .: ... .:. ..:.:::: :.::: .:.:.::
NP_000 I---PLSE-----TSSTKLSHIDEYISS-----SPTYQTVPDFQRVQITGDYASGVTVED
120 130 140 150 160
160 170 180 190 200 210
pF1KE6 YEQAAKSLAKALMIREKYARLAYHRFPRITSQYLGHPRADTAPPEEGL-PDFHPPPLPQE
.: . :.: .:: ::::: . ...:::. :.:: . ... .:.. : : :: :
NP_000 FEIVCKGLYRALCIREKYMQKSFQRFPKTPSKYLRNIDGEAWVANESFYPVFTPPVKKGE
170 180 190 200 210 220
220 230 240 250 260 270
pF1KE6 DPYCLDDAPPNLDYLVHMQGGILFVYDNKKMLEHQEPHSLPYPDLETYTVDMSHILALIT
::. :. : :: : ..:. :...:: :. . ..::. ::::.:.:. ::. .::::.
NP_000 DPFRTDNLPENLGYHLKMKDGVVYVYPNEAAVSKDEPKPLPYPNLDTFLDDMNFLLALIA
230 240 250 260 270 280
280 290 300 310 320 330
pF1KE6 DGPTKTYCHRRLNFLESKFSLHEMLNEMSEFKELKSNPHRDFYNVRKVDTHIHAAACMNQ
.::.::: ::::.:: :::..:.:::::.:.::::.:::::::: :::::::::::::::
NP_000 QGPVKTYTHRRLKFLSSKFQVHQMLNEMDELKELKNNPHRDFYNCRKVDTHIHAAACMNQ
290 300 310 320 330 340
340 350 360 370 380 390
pF1KE6 KHLLRFIKHTYQTEPDRTVAEKRGRKITLRQVFDGLHMDPYDLTVDSLDVHAGRQTFHRF
::::::::..:: . ::.: . ...::...: :.: ::::::::::::::::::.::
NP_000 KHLLRFIKKSYQIDADRVVYSTKEKNLTLKELFAKLKMHPYDLTVDSLDVHAGRQTFQRF
350 360 370 380 390 400
400 410 420 430 440 450
pF1KE6 DKFNSKYNPVGASELRDLYLKTENYLGGEYFARMVKEVARELEESKYQYSEPRLSIYGRS
::::.:::::::::::::::::.::..::::: ..:::. .: :.:::..::::::::::
NP_000 DKFNDKYNPVGASELRDLYLKTDNYINGEYFATIIKEVGADLVEAKYQHAEPRLSIYGRS
410 420 430 440 450 460
460 470 480 490 500 510
pF1KE6 PEEWPNLAYWFIQHKVYSPNMRWIIQVPRIYDIFRSKKLLPNFGKMLENIFLPLFKATIN
:.:: .:. ::. .... ::: :.::::::::.::::..::.:::::::::.:.:.::::
NP_000 PDEWSKLSSWFVCNRIHCPNMTWMIQVPRIYDVFRSKNFLPHFGKMLENIFMPVFEATIN
470 480 490 500 510 520
520 530 540 550 560 570
pF1KE6 PQDHRELHLFLKYVTGFDSVDDESKHSDHMFSDKSPNPDVWTSEQNPPYSYYLYYMYANI
:: :: .:::..::::::::::::: ::::.:::.:. :: :.:: :.:: :::::::
NP_000 PQADPELSVFLKHITGFDSVDDESKHSGHMFSSKSPKPQEWTLEKNPSYTYYAYYMYANI
530 540 550 560 570 580
580 590 600 610 620 630
pF1KE6 MVLNNLRRERGLSTFLFRPHCGEAGSITHLVSAFLTADNISHGLLLKKSPVLQYLYYLAQ
::::.::.:::..::::::::::::..:::..::. ::.::::: ::::::::::..:::
NP_000 MVLNSLRKERGMNTFLFRPHCGEAGALTHLMTAFMIADDISHGLNLKKSPVLQYLFFLAQ
590 600 610 620 630 640
640 650 660 670 680 690
pF1KE6 IPIAMSPLSNNSLFLEYSKNPLREFLHKGLHVSLSTDDPMQFHYTKEALMEEYAIAAQVW
:::::::::::::::::.:::. .::.::: .:::::::::::.::: :::::::::::.
NP_000 IPIAMSPLSNNSLFLEYAKNPFLDFLQKGLMISLSTDDPMQFHFTKEPLMEEYAIAAQVF
650 660 670 680 690 700
700 710 720 730 740 750
pF1KE6 KLSTCDLCEIARNSVLQSGLSHQEKQKFLGQNYYKEGPEGNDIRKTNVAQIRMAFRYETL
::::::.::.::::::: :.::.:: ::::.:: .::: :::::.:::::::::.::::
NP_000 KLSTCDMCEVARNSVLQCGISHEEKVKFLGDNYLEEGPAGNDIRRTNVAQIRMAYRYETW
710 720 730 740 750 760
760 770
pF1KE6 CNELSFLSDAMKSEEITALTN
: ::.......:: :
NP_000 CYELNLIAEGLKSTE
770 780
>>NP_631895 (OMIM: 102771,615686,615809) AMP deaminase 2 (798 aa)
initn: 2576 init1: 2388 opt: 2510 Z-score: 2076.3 bits: 395.0 E(85289): 6.5e-109
Smith-Waterman score: 2631; 51.9% identity (76.6% similar) in 786 aa overlap (7-774:23-785)
10 20 30 40
pF1KE6 MALSSEPAEMPRQFPKLNI-SEVDEQVRLLAEKVFAKVLREEDS
:: ..:: :.. . .: . . .::..:.. : : .
NP_631 MASEARGGLGAPPLQSARSLPGPAPCLKHFP-LDLRTSMDGKCKEIAEELFTRSLAESEL
10 20 30 40 50
50 60 70 80 90 100
pF1KE6 KDALSLFTVPEDCPIGQKEAKERELQKELAEQKSVETA---KRKKSFKMIRSQSLSLQMP
..: : ::. :: : : ....:....... ..: . :..: :.: .::.
NP_631 RSAPYEF--PEESPIEQLEERRQRLERQISQDVKLEPDILLRAKQDFLKTDSDS-DLQLY
60 70 80 90 100 110
110 120 130 140 150 160
pF1KE6 PQQDWKGPPAASPAMSPTTPVVTGATSLPTPAPYAMPEFQRVTISGDYCAGITLEDYEQA
.: .: : :: :::::::::. :. . : .:
NP_631 KEQG-EGQ---------------GDRSL-RERDVLEREFQRVTISGEEKCGVPFTDLLDA
120 130 140 150
170 180 190 200
pF1KE6 AKSLAKALMIREKYARLAYHRFPRITSQYL---GHPRADTAPPEEGLPD--------FHP
:::...::.::::: :. . : : .:: .. .: :.: :: ::
NP_631 AKSVVRALFIREKYMALSLQSFCPTTRRYLQQLAEKPLETRTYEQG-PDTPVSADAPVHP
160 170 180 190 200 210
210 220 230 240 250 260
pF1KE6 PPLPQEDPY--CLDDA-PPNLDYLVHMQGGILFVYDNKKMLEHQEPHSLPYPDLETYTVD
: : :. :: : .. : .: ..: :.. :: .. :: ::::::. ...:
NP_631 PALEQH-PYEHCEPSTMPGDLGLGLRMVRGVVHVYTRREPDEHCSEVELPYPDLQEFVAD
220 230 240 250 260 270
270 280 290 300 310 320
pF1KE6 MSHILALITDGPTKTYCHRRLNFLESKFSLHEMLNEMSEFKELKSNPHRDFYNVRKVDTH
.. ..::: .:: :..:.:::..: :::..: .::::.:. :. :::::::.::::::
NP_631 VNVLMALIINGPIKSFCYRRLQYLSSKFQMHVLLNEMKELAAQKKVPHRDFYNIRKVDTH
280 290 300 310 320 330
330 340 350 360 370 380
pF1KE6 IHAAACMNQKHLLRFIKHTYQTEPDRTVAEKRGRKITLRQVFDGLHMDPYDLTVDSLDVH
:::..::::::::::::.... . .. : ..::. :::.::..... :::.::.::::
NP_631 IHASSCMNQKHLLRFIKRAMKRHLEEIVHVEQGREQTLREVFESMNLTAYDLSVDTLDVH
340 350 360 370 380 390
390 400 410 420 430 440
pF1KE6 AGRQTFHRFDKFNSKYNPVGASELRDLYLKTENYLGGEYFARMVKEVARELEESKYQYSE
: :.:::::::::.::::.: : ::....::.: ..:.:::...::: .::::::: .:
NP_631 ADRNTFHRFDKFNAKYNPIGESVLREIFIKTDNRVSGKYFAHIIKEVMSDLEESKYQNAE
400 410 420 430 440 450
450 460 470 480 490 500
pF1KE6 PRLSIYGRSPEEWPNLAYWFIQHKVYSPNMRWIIQVPRIYDIFRSKKLLPNFGKMLENIF
:::::::: .:: .:: : ..:.:.:::.::..::::..:..:.: : :: .::::::
NP_631 LRLSIYGRSRDEWDKLARWAVMHRVHSPNVRWLVQVPRLFDVYRTKGQLANFQEMLENIF
460 470 480 490 500 510
510 520 530 540 550 560
pF1KE6 LPLFKATINPQDHRELHLFLKYVTGFDSVDDESKHSDHMFSDKSPNPDVWTSEQNPPYSY
::::.::..: .: ::::::..: :::::::::: .:.:. .:: :..:. :.::::.:
NP_631 LPLFEATVHPASHPELHLFLEHVDGFDSVDDESKPENHVFNLESPLPEAWVEEDNPPYAY
520 530 540 550 560 570
570 580 590 600 610 620
pF1KE6 YLYYMYANIMVLNNLRRERGLSTFLFRPHCGEAGSITHLVSAFLTADNISHGLLLKKSPV
:::: .::. .::.:::.::. ::..:::::::: : ::::::. :.::::::::.:.::
NP_631 YLYYTFANMAMLNHLRRQRGFHTFVLRPHCGEAGPIHHLVSAFMLAENISHGLLLRKAPV
580 590 600 610 620 630
630 640 650 660 670 680
pF1KE6 LQYLYYLAQIPIAMSPLSNNSLFLEYSKNPLREFLHKGLHVSLSTDDPMQFHYTKEALME
:::::::::: ::::::::::::: : .::: :.: .:: ::::::::.:::.::: :::
NP_631 LQYLYYLAQIGIAMSPLSNNSLFLSYHRNPLPEYLSRGLMVSLSTDDPLQFHFTKEPLME
640 650 660 670 680 690
690 700 710 720 730 740
pF1KE6 EYAIAAQVWKLSTCDLCEIARNSVLQSGLSHQEKQKFLGQNYYKEGPEGNDIRKTNVAQI
::.::.::::::.::.::.::::::.::.::. :...:: :: ::::::::::.::: .:
NP_631 EYSIATQVWKLSSCDMCELARNSVLMSGFSHKVKSHWLGPNYTKEGPEGNDIRRTNVPDI
700 710 720 730 740 750
750 760 770
pF1KE6 RMAFRYETLCNELSFLSDAMKSEEITALTN
:...::::::.::.....:..:: . ..
NP_631 RVGYRYETLCQELALITQAVQSEMLETIPEEAGITMSPGPQ
760 770 780 790
>>NP_001244289 (OMIM: 102771,615686,615809) AMP deaminas (879 aa)
initn: 2576 init1: 2388 opt: 2510 Z-score: 2075.7 bits: 395.0 E(85289): 7e-109
Smith-Waterman score: 2631; 51.9% identity (76.6% similar) in 786 aa overlap (7-774:104-866)
10 20 30
pF1KE6 MALSSEPAEMPRQFPKLNI-SEVDEQVRLLAEKVFA
:: ..:: :.. . .: . . .::..:.
NP_001 RASLQASTAAPEARGGLGAPPLQSARSLPGPAPCLKHFP-LDLRTSMDGKCKEIAEELFT
80 90 100 110 120 130
40 50 60 70 80 90
pF1KE6 KVLREEDSKDALSLFTVPEDCPIGQKEAKERELQKELAEQKSVETA---KRKKSFKMIRS
. : : . ..: : ::. :: : : ....:....... ..: . :..: :
NP_001 RSLAESELRSAPYEF--PEESPIEQLEERRQRLERQISQDVKLEPDILLRAKQDFLKTDS
140 150 160 170 180 190
100 110 120 130 140 150
pF1KE6 QSLSLQMPPQQDWKGPPAASPAMSPTTPVVTGATSLPTPAPYAMPEFQRVTISGDYCAGI
.: .::. .: .: : :: :::::::::. :.
NP_001 DS-DLQLYKEQG-EGQ---------------GDRSL-RERDVLEREFQRVTISGEEKCGV
200 210 220 230
160 170 180 190 200
pF1KE6 TLEDYEQAAKSLAKALMIREKYARLAYHRFPRITSQYL---GHPRADTAPPEEGLPD---
. : .::::...::.::::: :. . : : .:: .. .: :.: ::
NP_001 PFTDLLDAAKSVVRALFIREKYMALSLQSFCPTTRRYLQQLAEKPLETRTYEQG-PDTPV
240 250 260 270 280 290
210 220 230 240 250
pF1KE6 -----FHPPPLPQEDPY--CLDDA-PPNLDYLVHMQGGILFVYDNKKMLEHQEPHSLPYP
::: : :. :: : .. : .: ..: :.. :: .. :: ::::
NP_001 SADAPVHPPALEQH-PYEHCEPSTMPGDLGLGLRMVRGVVHVYTRREPDEHCSEVELPYP
300 310 320 330 340 350
260 270 280 290 300 310
pF1KE6 DLETYTVDMSHILALITDGPTKTYCHRRLNFLESKFSLHEMLNEMSEFKELKSNPHRDFY
::. ...:.. ..::: .:: :..:.:::..: :::..: .::::.:. :. ::::::
NP_001 DLQEFVADVNVLMALIINGPIKSFCYRRLQYLSSKFQMHVLLNEMKELAAQKKVPHRDFY
360 370 380 390 400 410
320 330 340 350 360 370
pF1KE6 NVRKVDTHIHAAACMNQKHLLRFIKHTYQTEPDRTVAEKRGRKITLRQVFDGLHMDPYDL
:.:::::::::..::::::::::::.... . .. : ..::. :::.::..... :::
NP_001 NIRKVDTHIHASSCMNQKHLLRFIKRAMKRHLEEIVHVEQGREQTLREVFESMNLTAYDL
420 430 440 450 460 470
380 390 400 410 420 430
pF1KE6 TVDSLDVHAGRQTFHRFDKFNSKYNPVGASELRDLYLKTENYLGGEYFARMVKEVARELE
.::.::::: :.:::::::::.::::.: : ::....::.: ..:.:::...::: .::
NP_001 SVDTLDVHADRNTFHRFDKFNAKYNPIGESVLREIFIKTDNRVSGKYFAHIIKEVMSDLE
480 490 500 510 520 530
440 450 460 470 480 490
pF1KE6 ESKYQYSEPRLSIYGRSPEEWPNLAYWFIQHKVYSPNMRWIIQVPRIYDIFRSKKLLPNF
::::: .: :::::::: .:: .:: : ..:.:.:::.::..::::..:..:.: : ::
NP_001 ESKYQNAELRLSIYGRSRDEWDKLARWAVMHRVHSPNVRWLVQVPRLFDVYRTKGQLANF
540 550 560 570 580 590
500 510 520 530 540 550
pF1KE6 GKMLENIFLPLFKATINPQDHRELHLFLKYVTGFDSVDDESKHSDHMFSDKSPNPDVWTS
.::::::::::.::..: .: ::::::..: :::::::::: .:.:. .:: :..:.
NP_001 QEMLENIFLPLFEATVHPASHPELHLFLEHVDGFDSVDDESKPENHVFNLESPLPEAWVE
600 610 620 630 640 650
560 570 580 590 600 610
pF1KE6 EQNPPYSYYLYYMYANIMVLNNLRRERGLSTFLFRPHCGEAGSITHLVSAFLTADNISHG
:.::::.::::: .::. .::.:::.::. ::..:::::::: : ::::::. :.:::::
NP_001 EDNPPYAYYLYYTFANMAMLNHLRRQRGFHTFVLRPHCGEAGPIHHLVSAFMLAENISHG
660 670 680 690 700 710
620 630 640 650 660 670
pF1KE6 LLLKKSPVLQYLYYLAQIPIAMSPLSNNSLFLEYSKNPLREFLHKGLHVSLSTDDPMQFH
:::.:.:::::::::::: ::::::::::::: : .::: :.: .:: ::::::::.:::
NP_001 LLLRKAPVLQYLYYLAQIGIAMSPLSNNSLFLSYHRNPLPEYLSRGLMVSLSTDDPLQFH
720 730 740 750 760 770
680 690 700 710 720 730
pF1KE6 YTKEALMEEYAIAAQVWKLSTCDLCEIARNSVLQSGLSHQEKQKFLGQNYYKEGPEGNDI
.::: :::::.::.::::::.::.::.::::::.::.::. :...:: :: :::::::::
NP_001 FTKEPLMEEYSIATQVWKLSSCDMCELARNSVLMSGFSHKVKSHWLGPNYTKEGPEGNDI
780 790 800 810 820 830
740 750 760 770
pF1KE6 RKTNVAQIRMAFRYETLCNELSFLSDAMKSEEITALTN
:.::: .::...::::::.::.....:..:: . ..
NP_001 RRTNVPDIRVGYRYETLCQELALITQAVQSEMLETIPEEAGITMSPGPQ
840 850 860 870
>>NP_004028 (OMIM: 102771,615686,615809) AMP deaminase 2 (879 aa)
initn: 2576 init1: 2388 opt: 2510 Z-score: 2075.7 bits: 395.0 E(85289): 7e-109
Smith-Waterman score: 2631; 51.9% identity (76.6% similar) in 786 aa overlap (7-774:104-866)
10 20 30
pF1KE6 MALSSEPAEMPRQFPKLNI-SEVDEQVRLLAEKVFA
:: ..:: :.. . .: . . .::..:.
NP_004 RASLQASTAAPEARGGLGAPPLQSARSLPGPAPCLKHFP-LDLRTSMDGKCKEIAEELFT
80 90 100 110 120 130
40 50 60 70 80 90
pF1KE6 KVLREEDSKDALSLFTVPEDCPIGQKEAKERELQKELAEQKSVETA---KRKKSFKMIRS
. : : . ..: : ::. :: : : ....:....... ..: . :..: :
NP_004 RSLAESELRSAPYEF--PEESPIEQLEERRQRLERQISQDVKLEPDILLRAKQDFLKTDS
140 150 160 170 180 190
100 110 120 130 140 150
pF1KE6 QSLSLQMPPQQDWKGPPAASPAMSPTTPVVTGATSLPTPAPYAMPEFQRVTISGDYCAGI
.: .::. .: .: : :: :::::::::. :.
NP_004 DS-DLQLYKEQG-EGQ---------------GDRSL-RERDVLEREFQRVTISGEEKCGV
200 210 220 230
160 170 180 190 200
pF1KE6 TLEDYEQAAKSLAKALMIREKYARLAYHRFPRITSQYL---GHPRADTAPPEEGLPD---
. : .::::...::.::::: :. . : : .:: .. .: :.: ::
NP_004 PFTDLLDAAKSVVRALFIREKYMALSLQSFCPTTRRYLQQLAEKPLETRTYEQG-PDTPV
240 250 260 270 280 290
210 220 230 240 250
pF1KE6 -----FHPPPLPQEDPY--CLDDA-PPNLDYLVHMQGGILFVYDNKKMLEHQEPHSLPYP
::: : :. :: : .. : .: ..: :.. :: .. :: ::::
NP_004 SADAPVHPPALEQH-PYEHCEPSTMPGDLGLGLRMVRGVVHVYTRREPDEHCSEVELPYP
300 310 320 330 340 350
260 270 280 290 300 310
pF1KE6 DLETYTVDMSHILALITDGPTKTYCHRRLNFLESKFSLHEMLNEMSEFKELKSNPHRDFY
::. ...:.. ..::: .:: :..:.:::..: :::..: .::::.:. :. ::::::
NP_004 DLQEFVADVNVLMALIINGPIKSFCYRRLQYLSSKFQMHVLLNEMKELAAQKKVPHRDFY
360 370 380 390 400 410
320 330 340 350 360 370
pF1KE6 NVRKVDTHIHAAACMNQKHLLRFIKHTYQTEPDRTVAEKRGRKITLRQVFDGLHMDPYDL
:.:::::::::..::::::::::::.... . .. : ..::. :::.::..... :::
NP_004 NIRKVDTHIHASSCMNQKHLLRFIKRAMKRHLEEIVHVEQGREQTLREVFESMNLTAYDL
420 430 440 450 460 470
380 390 400 410 420 430
pF1KE6 TVDSLDVHAGRQTFHRFDKFNSKYNPVGASELRDLYLKTENYLGGEYFARMVKEVARELE
.::.::::: :.:::::::::.::::.: : ::....::.: ..:.:::...::: .::
NP_004 SVDTLDVHADRNTFHRFDKFNAKYNPIGESVLREIFIKTDNRVSGKYFAHIIKEVMSDLE
480 490 500 510 520 530
440 450 460 470 480 490
pF1KE6 ESKYQYSEPRLSIYGRSPEEWPNLAYWFIQHKVYSPNMRWIIQVPRIYDIFRSKKLLPNF
::::: .: :::::::: .:: .:: : ..:.:.:::.::..::::..:..:.: : ::
NP_004 ESKYQNAELRLSIYGRSRDEWDKLARWAVMHRVHSPNVRWLVQVPRLFDVYRTKGQLANF
540 550 560 570 580 590
500 510 520 530 540 550
pF1KE6 GKMLENIFLPLFKATINPQDHRELHLFLKYVTGFDSVDDESKHSDHMFSDKSPNPDVWTS
.::::::::::.::..: .: ::::::..: :::::::::: .:.:. .:: :..:.
NP_004 QEMLENIFLPLFEATVHPASHPELHLFLEHVDGFDSVDDESKPENHVFNLESPLPEAWVE
600 610 620 630 640 650
560 570 580 590 600 610
pF1KE6 EQNPPYSYYLYYMYANIMVLNNLRRERGLSTFLFRPHCGEAGSITHLVSAFLTADNISHG
:.::::.::::: .::. .::.:::.::. ::..:::::::: : ::::::. :.:::::
NP_004 EDNPPYAYYLYYTFANMAMLNHLRRQRGFHTFVLRPHCGEAGPIHHLVSAFMLAENISHG
660 670 680 690 700 710
620 630 640 650 660 670
pF1KE6 LLLKKSPVLQYLYYLAQIPIAMSPLSNNSLFLEYSKNPLREFLHKGLHVSLSTDDPMQFH
:::.:.:::::::::::: ::::::::::::: : .::: :.: .:: ::::::::.:::
NP_004 LLLRKAPVLQYLYYLAQIGIAMSPLSNNSLFLSYHRNPLPEYLSRGLMVSLSTDDPLQFH
720 730 740 750 760 770
680 690 700 710 720 730
pF1KE6 YTKEALMEEYAIAAQVWKLSTCDLCEIARNSVLQSGLSHQEKQKFLGQNYYKEGPEGNDI
.::: :::::.::.::::::.::.::.::::::.::.::. :...:: :: :::::::::
NP_004 FTKEPLMEEYSIATQVWKLSSCDMCELARNSVLMSGFSHKVKSHWLGPNYTKEGPEGNDI
780 790 800 810 820 830
740 750 760 770
pF1KE6 RKTNVAQIRMAFRYETLCNELSFLSDAMKSEEITALTN
:.::: .::...::::::.::.....:..:: . ..
NP_004 RRTNVPDIRVGYRYETLCQELALITQAVQSEMLETIPEEAGITMSPGPQ
840 850 860 870
776 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Nov 8 15:54:13 2016 done: Tue Nov 8 15:54:14 2016
Total Scan time: 7.730 Total Display time: 0.160
Function used was FASTA [36.3.4 Apr, 2011]