Result of FASTA (omim) for
pFN21AE6724
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE6724, 693 aa
1>>>pF1KE6724 693 - 693 aa - 693 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.2115+/-0.000433; mu= 20.4661+/- 0.027
mean_var=72.8487+/-14.997, 0's: 0 Z-trim(111.2): 37 B-trim: 347 in 1/53
Lambda= 0.150267
statistics sampled from 19669 (19696) to 19669 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.589), E-opt: 0.2 (0.231), width: 16
Scan time: 9.010
The best scores are: opt bits E(85289)
NP_003866 (OMIM: 600358) GMP synthase [glutamine-h ( 693) 4552 996.8 0
XP_011511565 (OMIM: 600358) PREDICTED: GMP synthas ( 699) 4494 984.2 0
XP_016862911 (OMIM: 600358) PREDICTED: GMP synthas ( 686) 4488 982.9 0
>>NP_003866 (OMIM: 600358) GMP synthase [glutamine-hydro (693 aa)
initn: 4552 init1: 4552 opt: 4552 Z-score: 5330.8 bits: 996.8 E(85289): 0
Smith-Waterman score: 4552; 100.0% identity (100.0% similar) in 693 aa overlap (1-693:1-693)
10 20 30 40 50 60
pF1KE6 MALCNGDSKLENAGGDLKDGHHHYEGAVVILDAGAQYGKVIDRRVRELFVQSEIFPLETP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 MALCNGDSKLENAGGDLKDGHHHYEGAVVILDAGAQYGKVIDRRVRELFVQSEIFPLETP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 AFAIKEQGFRAIIISGGPNSVYAEDAPWFDPAIFTIGKPVLGICYGMQMMNKVFGGTVHK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 AFAIKEQGFRAIIISGGPNSVYAEDAPWFDPAIFTIGKPVLGICYGMQMMNKVFGGTVHK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 KSVREDGVFNISVDNTCSLFRGLQKEEVVLLTHGDSVDKVADGFKVVARSGNIVAGIANE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 KSVREDGVFNISVDNTCSLFRGLQKEEVVLLTHGDSVDKVADGFKVVARSGNIVAGIANE
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE6 SKKLYGAQFHPEVGLTENGKVILKNFLYDIAGCSGTFTVQNRELECIREIKERVGTSKVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 SKKLYGAQFHPEVGLTENGKVILKNFLYDIAGCSGTFTVQNRELECIREIKERVGTSKVL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE6 VLLSGGVDSTVCTALLNRALNQEQVIAVHIDNGFMRKRESQSVEEALKKLGIQVKVINAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 VLLSGGVDSTVCTALLNRALNQEQVIAVHIDNGFMRKRESQSVEEALKKLGIQVKVINAA
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE6 HSFYNGTTTLPISDEDRTPRKRISKTLNMTTSPEEKRKIIGDTFVKIANEVIGEMNLKPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 HSFYNGTTTLPISDEDRTPRKRISKTLNMTTSPEEKRKIIGDTFVKIANEVIGEMNLKPE
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE6 EVFLAQGTLRPDLIESASLVASGKAELIKTHHNDTELIRKLREEGKVIEPLKDFHKDEVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 EVFLAQGTLRPDLIESASLVASGKAELIKTHHNDTELIRKLREEGKVIEPLKDFHKDEVR
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE6 ILGRELGLPEELVSRHPFPGPGLAIRVICAEEPYICKDFPETNNILKIVADFSASVKKPH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 ILGRELGLPEELVSRHPFPGPGLAIRVICAEEPYICKDFPETNNILKIVADFSASVKKPH
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE6 TLLQRVKACTTEEDQEKLMQITSLHSLNAFLLPIKTVGVQGDCRSYSYVCGISSKDEPDW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 TLLQRVKACTTEEDQEKLMQITSLHSLNAFLLPIKTVGVQGDCRSYSYVCGISSKDEPDW
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE6 ESLIFLARLIPRMCHNVNRVVYIFGPPVKEPPTDVTPTFLTTGVLSTLRQADFEAHNILR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 ESLIFLARLIPRMCHNVNRVVYIFGPPVKEPPTDVTPTFLTTGVLSTLRQADFEAHNILR
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE6 ESGYAGKISQMPVILTPLHFDRDPLQKQPSCQRSVVIRTFITSDFMTGIPATPGNEIPVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 ESGYAGKISQMPVILTPLHFDRDPLQKQPSCQRSVVIRTFITSDFMTGIPATPGNEIPVE
610 620 630 640 650 660
670 680 690
pF1KE6 VVLKMVTEIKKIPGISRIMYDLTSKPPGTTEWE
:::::::::::::::::::::::::::::::::
NP_003 VVLKMVTEIKKIPGISRIMYDLTSKPPGTTEWE
670 680 690
>>XP_011511565 (OMIM: 600358) PREDICTED: GMP synthase [g (699 aa)
initn: 4494 init1: 4494 opt: 4494 Z-score: 5262.7 bits: 984.2 E(85289): 0
Smith-Waterman score: 4494; 100.0% identity (100.0% similar) in 685 aa overlap (9-693:15-699)
10 20 30 40 50
pF1KE6 MALCNGDSKLENAGGDLKDGHHHYEGAVVILDAGAQYGKVIDRRVRELFVQSEI
::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MALESSNIQFSVQKKLENAGGDLKDGHHHYEGAVVILDAGAQYGKVIDRRVRELFVQSEI
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE6 FPLETPAFAIKEQGFRAIIISGGPNSVYAEDAPWFDPAIFTIGKPVLGICYGMQMMNKVF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FPLETPAFAIKEQGFRAIIISGGPNSVYAEDAPWFDPAIFTIGKPVLGICYGMQMMNKVF
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE6 GGTVHKKSVREDGVFNISVDNTCSLFRGLQKEEVVLLTHGDSVDKVADGFKVVARSGNIV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GGTVHKKSVREDGVFNISVDNTCSLFRGLQKEEVVLLTHGDSVDKVADGFKVVARSGNIV
130 140 150 160 170 180
180 190 200 210 220 230
pF1KE6 AGIANESKKLYGAQFHPEVGLTENGKVILKNFLYDIAGCSGTFTVQNRELECIREIKERV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AGIANESKKLYGAQFHPEVGLTENGKVILKNFLYDIAGCSGTFTVQNRELECIREIKERV
190 200 210 220 230 240
240 250 260 270 280 290
pF1KE6 GTSKVLVLLSGGVDSTVCTALLNRALNQEQVIAVHIDNGFMRKRESQSVEEALKKLGIQV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GTSKVLVLLSGGVDSTVCTALLNRALNQEQVIAVHIDNGFMRKRESQSVEEALKKLGIQV
250 260 270 280 290 300
300 310 320 330 340 350
pF1KE6 KVINAAHSFYNGTTTLPISDEDRTPRKRISKTLNMTTSPEEKRKIIGDTFVKIANEVIGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KVINAAHSFYNGTTTLPISDEDRTPRKRISKTLNMTTSPEEKRKIIGDTFVKIANEVIGE
310 320 330 340 350 360
360 370 380 390 400 410
pF1KE6 MNLKPEEVFLAQGTLRPDLIESASLVASGKAELIKTHHNDTELIRKLREEGKVIEPLKDF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MNLKPEEVFLAQGTLRPDLIESASLVASGKAELIKTHHNDTELIRKLREEGKVIEPLKDF
370 380 390 400 410 420
420 430 440 450 460 470
pF1KE6 HKDEVRILGRELGLPEELVSRHPFPGPGLAIRVICAEEPYICKDFPETNNILKIVADFSA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HKDEVRILGRELGLPEELVSRHPFPGPGLAIRVICAEEPYICKDFPETNNILKIVADFSA
430 440 450 460 470 480
480 490 500 510 520 530
pF1KE6 SVKKPHTLLQRVKACTTEEDQEKLMQITSLHSLNAFLLPIKTVGVQGDCRSYSYVCGISS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SVKKPHTLLQRVKACTTEEDQEKLMQITSLHSLNAFLLPIKTVGVQGDCRSYSYVCGISS
490 500 510 520 530 540
540 550 560 570 580 590
pF1KE6 KDEPDWESLIFLARLIPRMCHNVNRVVYIFGPPVKEPPTDVTPTFLTTGVLSTLRQADFE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KDEPDWESLIFLARLIPRMCHNVNRVVYIFGPPVKEPPTDVTPTFLTTGVLSTLRQADFE
550 560 570 580 590 600
600 610 620 630 640 650
pF1KE6 AHNILRESGYAGKISQMPVILTPLHFDRDPLQKQPSCQRSVVIRTFITSDFMTGIPATPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AHNILRESGYAGKISQMPVILTPLHFDRDPLQKQPSCQRSVVIRTFITSDFMTGIPATPG
610 620 630 640 650 660
660 670 680 690
pF1KE6 NEIPVEVVLKMVTEIKKIPGISRIMYDLTSKPPGTTEWE
:::::::::::::::::::::::::::::::::::::::
XP_011 NEIPVEVVLKMVTEIKKIPGISRIMYDLTSKPPGTTEWE
670 680 690
>>XP_016862911 (OMIM: 600358) PREDICTED: GMP synthase [g (686 aa)
initn: 4488 init1: 4488 opt: 4488 Z-score: 5255.8 bits: 982.9 E(85289): 0
Smith-Waterman score: 4488; 100.0% identity (100.0% similar) in 684 aa overlap (10-693:3-686)
10 20 30 40 50 60
pF1KE6 MALCNGDSKLENAGGDLKDGHHHYEGAVVILDAGAQYGKVIDRRVRELFVQSEIFPLETP
:::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MLLENAGGDLKDGHHHYEGAVVILDAGAQYGKVIDRRVRELFVQSEIFPLETP
10 20 30 40 50
70 80 90 100 110 120
pF1KE6 AFAIKEQGFRAIIISGGPNSVYAEDAPWFDPAIFTIGKPVLGICYGMQMMNKVFGGTVHK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AFAIKEQGFRAIIISGGPNSVYAEDAPWFDPAIFTIGKPVLGICYGMQMMNKVFGGTVHK
60 70 80 90 100 110
130 140 150 160 170 180
pF1KE6 KSVREDGVFNISVDNTCSLFRGLQKEEVVLLTHGDSVDKVADGFKVVARSGNIVAGIANE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KSVREDGVFNISVDNTCSLFRGLQKEEVVLLTHGDSVDKVADGFKVVARSGNIVAGIANE
120 130 140 150 160 170
190 200 210 220 230 240
pF1KE6 SKKLYGAQFHPEVGLTENGKVILKNFLYDIAGCSGTFTVQNRELECIREIKERVGTSKVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SKKLYGAQFHPEVGLTENGKVILKNFLYDIAGCSGTFTVQNRELECIREIKERVGTSKVL
180 190 200 210 220 230
250 260 270 280 290 300
pF1KE6 VLLSGGVDSTVCTALLNRALNQEQVIAVHIDNGFMRKRESQSVEEALKKLGIQVKVINAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VLLSGGVDSTVCTALLNRALNQEQVIAVHIDNGFMRKRESQSVEEALKKLGIQVKVINAA
240 250 260 270 280 290
310 320 330 340 350 360
pF1KE6 HSFYNGTTTLPISDEDRTPRKRISKTLNMTTSPEEKRKIIGDTFVKIANEVIGEMNLKPE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 HSFYNGTTTLPISDEDRTPRKRISKTLNMTTSPEEKRKIIGDTFVKIANEVIGEMNLKPE
300 310 320 330 340 350
370 380 390 400 410 420
pF1KE6 EVFLAQGTLRPDLIESASLVASGKAELIKTHHNDTELIRKLREEGKVIEPLKDFHKDEVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EVFLAQGTLRPDLIESASLVASGKAELIKTHHNDTELIRKLREEGKVIEPLKDFHKDEVR
360 370 380 390 400 410
430 440 450 460 470 480
pF1KE6 ILGRELGLPEELVSRHPFPGPGLAIRVICAEEPYICKDFPETNNILKIVADFSASVKKPH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ILGRELGLPEELVSRHPFPGPGLAIRVICAEEPYICKDFPETNNILKIVADFSASVKKPH
420 430 440 450 460 470
490 500 510 520 530 540
pF1KE6 TLLQRVKACTTEEDQEKLMQITSLHSLNAFLLPIKTVGVQGDCRSYSYVCGISSKDEPDW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TLLQRVKACTTEEDQEKLMQITSLHSLNAFLLPIKTVGVQGDCRSYSYVCGISSKDEPDW
480 490 500 510 520 530
550 560 570 580 590 600
pF1KE6 ESLIFLARLIPRMCHNVNRVVYIFGPPVKEPPTDVTPTFLTTGVLSTLRQADFEAHNILR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ESLIFLARLIPRMCHNVNRVVYIFGPPVKEPPTDVTPTFLTTGVLSTLRQADFEAHNILR
540 550 560 570 580 590
610 620 630 640 650 660
pF1KE6 ESGYAGKISQMPVILTPLHFDRDPLQKQPSCQRSVVIRTFITSDFMTGIPATPGNEIPVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ESGYAGKISQMPVILTPLHFDRDPLQKQPSCQRSVVIRTFITSDFMTGIPATPGNEIPVE
600 610 620 630 640 650
670 680 690
pF1KE6 VVLKMVTEIKKIPGISRIMYDLTSKPPGTTEWE
:::::::::::::::::::::::::::::::::
XP_016 VVLKMVTEIKKIPGISRIMYDLTSKPPGTTEWE
660 670 680
693 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Nov 8 15:44:00 2016 done: Tue Nov 8 15:44:01 2016
Total Scan time: 9.010 Total Display time: 0.050
Function used was FASTA [36.3.4 Apr, 2011]