Result of FASTA (omim) for
pFN21AE6723
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE6723, 699 aa
1>>>pF1KE6723 699 - 699 aa - 699 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.8807+/-0.00044; mu= 13.6884+/- 0.027
mean_var=146.2810+/-29.293, 0's: 0 Z-trim(113.4): 96 B-trim: 0 in 0/54
Lambda= 0.106043
statistics sampled from 22629 (22725) to 22629 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.625), E-opt: 0.2 (0.266), width: 16
Scan time: 8.750
The best scores are: opt bits E(85289)
NP_036276 (OMIM: 244400,604366) dynein intermediat ( 699) 4656 725.0 2.4e-208
NP_001268357 (OMIM: 244400,604366) dynein intermed ( 703) 4638 722.2 1.6e-207
XP_011516149 (OMIM: 244400,604366) PREDICTED: dyne ( 621) 4040 630.7 5.2e-180
XP_011516148 (OMIM: 244400,604366) PREDICTED: dyne ( 660) 4040 630.7 5.5e-180
XP_006716821 (OMIM: 244400,604366) PREDICTED: dyne ( 522) 3502 548.3 2.7e-155
XP_011516151 (OMIM: 244400,604366) PREDICTED: dyne ( 546) 3462 542.2 2e-153
XP_016870114 (OMIM: 244400,604366) PREDICTED: dyne ( 613) 2918 459.0 2.4e-128
XP_011516152 (OMIM: 244400,604366) PREDICTED: dyne ( 477) 2911 457.8 4.2e-128
XP_011516150 (OMIM: 244400,604366) PREDICTED: dyne ( 617) 2900 456.3 1.6e-127
NP_075462 (OMIM: 605483,612444) dynein intermediat ( 605) 486 86.9 2.4e-16
XP_011523427 (OMIM: 605483,612444) PREDICTED: dyne ( 649) 486 87.0 2.5e-16
NP_001307813 (OMIM: 603331) cytoplasmic dynein 1 i ( 611) 371 69.4 4.8e-11
NP_001258719 (OMIM: 603331) cytoplasmic dynein 1 i ( 611) 371 69.4 4.8e-11
NP_001258718 (OMIM: 603331) cytoplasmic dynein 1 i ( 612) 371 69.4 4.8e-11
NP_001258717 (OMIM: 603331) cytoplasmic dynein 1 i ( 612) 371 69.4 4.8e-11
NP_001258715 (OMIM: 603331) cytoplasmic dynein 1 i ( 630) 371 69.4 4.9e-11
NP_001258716 (OMIM: 603331) cytoplasmic dynein 1 i ( 630) 371 69.4 4.9e-11
XP_006712410 (OMIM: 603331) PREDICTED: cytoplasmic ( 631) 371 69.4 4.9e-11
XP_016859014 (OMIM: 603331) PREDICTED: cytoplasmic ( 631) 371 69.4 4.9e-11
NP_001307811 (OMIM: 603331) cytoplasmic dynein 1 i ( 632) 371 69.4 4.9e-11
NP_001307812 (OMIM: 603331) cytoplasmic dynein 1 i ( 632) 371 69.4 4.9e-11
NP_001258714 (OMIM: 603331) cytoplasmic dynein 1 i ( 638) 371 69.4 5e-11
NP_001369 (OMIM: 603331) cytoplasmic dynein 1 inte ( 638) 371 69.4 5e-11
NP_001265351 (OMIM: 603772) cytoplasmic dynein 1 i ( 602) 362 68.0 1.2e-10
NP_001129029 (OMIM: 603772) cytoplasmic dynein 1 i ( 608) 354 66.8 2.9e-10
NP_001265350 (OMIM: 603772) cytoplasmic dynein 1 i ( 625) 354 66.8 3e-10
XP_016867294 (OMIM: 603772) PREDICTED: cytoplasmic ( 628) 354 66.8 3e-10
XP_011514164 (OMIM: 603772) PREDICTED: cytoplasmic ( 628) 354 66.8 3e-10
NP_001129028 (OMIM: 603772) cytoplasmic dynein 1 i ( 628) 354 66.8 3e-10
XP_011514163 (OMIM: 603772) PREDICTED: cytoplasmic ( 645) 354 66.8 3e-10
XP_016867293 (OMIM: 603772) PREDICTED: cytoplasmic ( 645) 354 66.8 3e-10
NP_004402 (OMIM: 603772) cytoplasmic dynein 1 inte ( 645) 354 66.8 3e-10
XP_016867295 (OMIM: 603772) PREDICTED: cytoplasmic ( 513) 267 53.4 2.6e-06
XP_011514165 (OMIM: 603772) PREDICTED: cytoplasmic ( 530) 267 53.4 2.7e-06
NP_443076 (OMIM: 613363,615633) WD repeat-containi ( 536) 237 48.8 6.5e-05
>>NP_036276 (OMIM: 244400,604366) dynein intermediate ch (699 aa)
initn: 4656 init1: 4656 opt: 4656 Z-score: 3861.4 bits: 725.0 E(85289): 2.4e-208
Smith-Waterman score: 4656; 99.6% identity (99.7% similar) in 699 aa overlap (1-699:1-699)
10 20 30 40 50 60
pF1KE6 MIPASAKSPHKQPHKQSISIGRGTRKRDEDSGTEVGEGTDEWAQSKATVRPPDQLELTDA
:::::::.::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 MIPASAKAPHKQPHKQSISIGRGTRKRDEDSGTEVGEGTDEWAQSKATVRPPDQLELTDA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 ELKEEFTRILTANNPHAPQNIVRYSFKEGTYKPIGFVNQLAVHYTQVGNLIPKDSDEGRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 ELKEEFTRILTANNPHAPQNIVRYSFKEGTYKPIGFVNQLAVHYTQVGNLIPKDSDEGRR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 QHYRDELVAGSQESVKVISETGNLEEDEEPKELETEPGSQTDVPAAGAAEKVTEEELMTP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 QHYRDELVAGSQESVKVISETGNLEEDEEPKELETEPGSQTDVPAAGAAEKVTEEELMTP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE6 KQPKERKLTNQFNFSERASQTCNNPVRDRECQTEPPPRTNFSATANQWEIYDAYVEELEK
::::::::::::::::::::: ::::::::::::::::::::::::::::::::::::::
NP_036 KQPKERKLTNQFNFSERASQTYNNPVRDRECQTEPPPRTNFSATANQWEIYDAYVEELEK
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE6 QEKTKEKEKAKTPVAKKSGKMAMRKLTSMESQTDDLIKLSQAAKIMERMVNQNTYDDIAQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 QEKTKEKEKAKTPVAKKSGKMAMRKLTSMESQTDDLIKLSQAAKIMERMVNQNTYDDIAQ
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE6 DFKYYDDAADEYRDQVGTLLPLWKFQNDKAKRLSVTALCWNPKYRDLFAVGYGSYDFMKQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 DFKYYDDAADEYRDQVGTLLPLWKFQNDKAKRLSVTALCWNPKYRDLFAVGYGSYDFMKQ
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE6 SRGMLLLYSLKNPSFPEYMFSSNSGVMCLDIHVDHPYLVAVGHYDGNVAIYNLKKPHSQP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 SRGMLLLYSLKNPSFPEYMFSSNSGVMCLDIHVDHPYLVAVGHYDGNVAIYNLKKPHSQP
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE6 SFCSSAKSGKHSDPVWQVKWQKDDMDQNLNFFSVSSDGRIVSWTLVKRKLVHIDVIKLKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 SFCSSAKSGKHSDPVWQVKWQKDDMDQNLNFFSVSSDGRIVSWTLVKRKLVHIDVIKLKV
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE6 EGSTTEVPEGLQLHQVGCGTAFDFHKEIDYMFLVGTEEGKIYKCSKSYSSQFLDTYDAHN
:::::::::::::: :::::::::::::::::::::::::::::::::::::::::::::
NP_036 EGSTTEVPEGLQLHPVGCGTAFDFHKEIDYMFLVGTEEGKIYKCSKSYSSQFLDTYDAHN
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE6 MSVDTVSWNPYHTKVFMSCSSDWTVKIWDHTIKTPMFIYDLNSAVGDVAWAPYSSTVFAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 MSVDTVSWNPYHTKVFMSCSSDWTVKIWDHTIKTPMFIYDLNSAVGDVAWAPYSSTVFAA
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE6 VTTDGKAHIFDLAINKYEAICNQPVAAKKNRLTHVQFNLIHPIIIVGDDRGHIISLKLSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 VTTDGKAHIFDLAINKYEAICNQPVAAKKNRLTHVQFNLIHPIIIVGDDRGHIISLKLSP
610 620 630 640 650 660
670 680 690
pF1KE6 NLRKMPKEKKGQEVQKGPAVEIAKLDKLLNLVREVKIKT
:::::::::::::::::::::::::::::::::::::::
NP_036 NLRKMPKEKKGQEVQKGPAVEIAKLDKLLNLVREVKIKT
670 680 690
>>NP_001268357 (OMIM: 244400,604366) dynein intermediate (703 aa)
initn: 3797 init1: 3797 opt: 4638 Z-score: 3846.4 bits: 722.2 E(85289): 1.6e-207
Smith-Waterman score: 4638; 99.0% identity (99.1% similar) in 703 aa overlap (1-699:1-703)
10 20 30 40 50 60
pF1KE6 MIPASAKSPHKQPHKQSISIGRGTRKRDEDSGTEVGEGTDEWAQSKATVRPPDQLELTDA
:::::::.::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MIPASAKAPHKQPHKQSISIGRGTRKRDEDSGTEVGEGTDEWAQSKATVRPPDQLELTDA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 ELKEEFTRILTANNPHAPQNIVRYSFKEGTYKPIGFVNQLAVHYTQVGNLIPKDSDEGRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ELKEEFTRILTANNPHAPQNIVRYSFKEGTYKPIGFVNQLAVHYTQVGNLIPKDSDEGRR
70 80 90 100 110 120
130 140 150 160 170
pF1KE6 QHYRDELVA----GSQESVKVISETGNLEEDEEPKELETEPGSQTDVPAAGAAEKVTEEE
::::::::: :::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QHYRDELVAVSYQGSQESVKVISETGNLEEDEEPKELETEPGSQTDVPAAGAAEKVTEEE
130 140 150 160 170 180
180 190 200 210 220 230
pF1KE6 LMTPKQPKERKLTNQFNFSERASQTCNNPVRDRECQTEPPPRTNFSATANQWEIYDAYVE
::::::::::::::::::::::::: ::::::::::::::::::::::::::::::::::
NP_001 LMTPKQPKERKLTNQFNFSERASQTYNNPVRDRECQTEPPPRTNFSATANQWEIYDAYVE
190 200 210 220 230 240
240 250 260 270 280 290
pF1KE6 ELEKQEKTKEKEKAKTPVAKKSGKMAMRKLTSMESQTDDLIKLSQAAKIMERMVNQNTYD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ELEKQEKTKEKEKAKTPVAKKSGKMAMRKLTSMESQTDDLIKLSQAAKIMERMVNQNTYD
250 260 270 280 290 300
300 310 320 330 340 350
pF1KE6 DIAQDFKYYDDAADEYRDQVGTLLPLWKFQNDKAKRLSVTALCWNPKYRDLFAVGYGSYD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DIAQDFKYYDDAADEYRDQVGTLLPLWKFQNDKAKRLSVTALCWNPKYRDLFAVGYGSYD
310 320 330 340 350 360
360 370 380 390 400 410
pF1KE6 FMKQSRGMLLLYSLKNPSFPEYMFSSNSGVMCLDIHVDHPYLVAVGHYDGNVAIYNLKKP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FMKQSRGMLLLYSLKNPSFPEYMFSSNSGVMCLDIHVDHPYLVAVGHYDGNVAIYNLKKP
370 380 390 400 410 420
420 430 440 450 460 470
pF1KE6 HSQPSFCSSAKSGKHSDPVWQVKWQKDDMDQNLNFFSVSSDGRIVSWTLVKRKLVHIDVI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HSQPSFCSSAKSGKHSDPVWQVKWQKDDMDQNLNFFSVSSDGRIVSWTLVKRKLVHIDVI
430 440 450 460 470 480
480 490 500 510 520 530
pF1KE6 KLKVEGSTTEVPEGLQLHQVGCGTAFDFHKEIDYMFLVGTEEGKIYKCSKSYSSQFLDTY
:::::::::::::::::: :::::::::::::::::::::::::::::::::::::::::
NP_001 KLKVEGSTTEVPEGLQLHPVGCGTAFDFHKEIDYMFLVGTEEGKIYKCSKSYSSQFLDTY
490 500 510 520 530 540
540 550 560 570 580 590
pF1KE6 DAHNMSVDTVSWNPYHTKVFMSCSSDWTVKIWDHTIKTPMFIYDLNSAVGDVAWAPYSST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DAHNMSVDTVSWNPYHTKVFMSCSSDWTVKIWDHTIKTPMFIYDLNSAVGDVAWAPYSST
550 560 570 580 590 600
600 610 620 630 640 650
pF1KE6 VFAAVTTDGKAHIFDLAINKYEAICNQPVAAKKNRLTHVQFNLIHPIIIVGDDRGHIISL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VFAAVTTDGKAHIFDLAINKYEAICNQPVAAKKNRLTHVQFNLIHPIIIVGDDRGHIISL
610 620 630 640 650 660
660 670 680 690
pF1KE6 KLSPNLRKMPKEKKGQEVQKGPAVEIAKLDKLLNLVREVKIKT
:::::::::::::::::::::::::::::::::::::::::::
NP_001 KLSPNLRKMPKEKKGQEVQKGPAVEIAKLDKLLNLVREVKIKT
670 680 690 700
>>XP_011516149 (OMIM: 244400,604366) PREDICTED: dynein i (621 aa)
initn: 4080 init1: 3199 opt: 4040 Z-score: 3352.7 bits: 630.7 E(85289): 5.2e-180
Smith-Waterman score: 4040; 98.7% identity (99.0% similar) in 611 aa overlap (1-607:1-611)
10 20 30 40 50 60
pF1KE6 MIPASAKSPHKQPHKQSISIGRGTRKRDEDSGTEVGEGTDEWAQSKATVRPPDQLELTDA
:::::::.::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MIPASAKAPHKQPHKQSISIGRGTRKRDEDSGTEVGEGTDEWAQSKATVRPPDQLELTDA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 ELKEEFTRILTANNPHAPQNIVRYSFKEGTYKPIGFVNQLAVHYTQVGNLIPKDSDEGRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ELKEEFTRILTANNPHAPQNIVRYSFKEGTYKPIGFVNQLAVHYTQVGNLIPKDSDEGRR
70 80 90 100 110 120
130 140 150 160 170
pF1KE6 QHYRDELVA----GSQESVKVISETGNLEEDEEPKELETEPGSQTDVPAAGAAEKVTEEE
::::::::: :::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QHYRDELVAVSYQGSQESVKVISETGNLEEDEEPKELETEPGSQTDVPAAGAAEKVTEEE
130 140 150 160 170 180
180 190 200 210 220 230
pF1KE6 LMTPKQPKERKLTNQFNFSERASQTCNNPVRDRECQTEPPPRTNFSATANQWEIYDAYVE
::::::::::::::::::::::::: ::::::::::::::::::::::::::::::::::
XP_011 LMTPKQPKERKLTNQFNFSERASQTYNNPVRDRECQTEPPPRTNFSATANQWEIYDAYVE
190 200 210 220 230 240
240 250 260 270 280 290
pF1KE6 ELEKQEKTKEKEKAKTPVAKKSGKMAMRKLTSMESQTDDLIKLSQAAKIMERMVNQNTYD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ELEKQEKTKEKEKAKTPVAKKSGKMAMRKLTSMESQTDDLIKLSQAAKIMERMVNQNTYD
250 260 270 280 290 300
300 310 320 330 340 350
pF1KE6 DIAQDFKYYDDAADEYRDQVGTLLPLWKFQNDKAKRLSVTALCWNPKYRDLFAVGYGSYD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DIAQDFKYYDDAADEYRDQVGTLLPLWKFQNDKAKRLSVTALCWNPKYRDLFAVGYGSYD
310 320 330 340 350 360
360 370 380 390 400 410
pF1KE6 FMKQSRGMLLLYSLKNPSFPEYMFSSNSGVMCLDIHVDHPYLVAVGHYDGNVAIYNLKKP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FMKQSRGMLLLYSLKNPSFPEYMFSSNSGVMCLDIHVDHPYLVAVGHYDGNVAIYNLKKP
370 380 390 400 410 420
420 430 440 450 460 470
pF1KE6 HSQPSFCSSAKSGKHSDPVWQVKWQKDDMDQNLNFFSVSSDGRIVSWTLVKRKLVHIDVI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HSQPSFCSSAKSGKHSDPVWQVKWQKDDMDQNLNFFSVSSDGRIVSWTLVKRKLVHIDVI
430 440 450 460 470 480
480 490 500 510 520 530
pF1KE6 KLKVEGSTTEVPEGLQLHQVGCGTAFDFHKEIDYMFLVGTEEGKIYKCSKSYSSQFLDTY
:::::::::::::::::: :::::::::::::::::::::::::::::::::::::::::
XP_011 KLKVEGSTTEVPEGLQLHPVGCGTAFDFHKEIDYMFLVGTEEGKIYKCSKSYSSQFLDTY
490 500 510 520 530 540
540 550 560 570 580 590
pF1KE6 DAHNMSVDTVSWNPYHTKVFMSCSSDWTVKIWDHTIKTPMFIYDLNSAVGDVAWAPYSST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DAHNMSVDTVSWNPYHTKVFMSCSSDWTVKIWDHTIKTPMFIYDLNSAVGDVAWAPYSST
550 560 570 580 590 600
600 610 620 630 640 650
pF1KE6 VFAAVTTDGKAHIFDLAINKYEAICNQPVAAKKNRLTHVQFNLIHPIIIVGDDRGHIISL
::::::::::.
XP_011 VFAAVTTDGKSFPRKSRDSFL
610 620
>>XP_011516148 (OMIM: 244400,604366) PREDICTED: dynein i (660 aa)
initn: 4080 init1: 3199 opt: 4040 Z-score: 3352.4 bits: 630.7 E(85289): 5.5e-180
Smith-Waterman score: 4040; 98.5% identity (99.0% similar) in 612 aa overlap (1-608:1-612)
10 20 30 40 50 60
pF1KE6 MIPASAKSPHKQPHKQSISIGRGTRKRDEDSGTEVGEGTDEWAQSKATVRPPDQLELTDA
:::::::.::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MIPASAKAPHKQPHKQSISIGRGTRKRDEDSGTEVGEGTDEWAQSKATVRPPDQLELTDA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 ELKEEFTRILTANNPHAPQNIVRYSFKEGTYKPIGFVNQLAVHYTQVGNLIPKDSDEGRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ELKEEFTRILTANNPHAPQNIVRYSFKEGTYKPIGFVNQLAVHYTQVGNLIPKDSDEGRR
70 80 90 100 110 120
130 140 150 160 170
pF1KE6 QHYRDELVA----GSQESVKVISETGNLEEDEEPKELETEPGSQTDVPAAGAAEKVTEEE
::::::::: :::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QHYRDELVAVSYQGSQESVKVISETGNLEEDEEPKELETEPGSQTDVPAAGAAEKVTEEE
130 140 150 160 170 180
180 190 200 210 220 230
pF1KE6 LMTPKQPKERKLTNQFNFSERASQTCNNPVRDRECQTEPPPRTNFSATANQWEIYDAYVE
::::::::::::::::::::::::: ::::::::::::::::::::::::::::::::::
XP_011 LMTPKQPKERKLTNQFNFSERASQTYNNPVRDRECQTEPPPRTNFSATANQWEIYDAYVE
190 200 210 220 230 240
240 250 260 270 280 290
pF1KE6 ELEKQEKTKEKEKAKTPVAKKSGKMAMRKLTSMESQTDDLIKLSQAAKIMERMVNQNTYD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ELEKQEKTKEKEKAKTPVAKKSGKMAMRKLTSMESQTDDLIKLSQAAKIMERMVNQNTYD
250 260 270 280 290 300
300 310 320 330 340 350
pF1KE6 DIAQDFKYYDDAADEYRDQVGTLLPLWKFQNDKAKRLSVTALCWNPKYRDLFAVGYGSYD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DIAQDFKYYDDAADEYRDQVGTLLPLWKFQNDKAKRLSVTALCWNPKYRDLFAVGYGSYD
310 320 330 340 350 360
360 370 380 390 400 410
pF1KE6 FMKQSRGMLLLYSLKNPSFPEYMFSSNSGVMCLDIHVDHPYLVAVGHYDGNVAIYNLKKP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FMKQSRGMLLLYSLKNPSFPEYMFSSNSGVMCLDIHVDHPYLVAVGHYDGNVAIYNLKKP
370 380 390 400 410 420
420 430 440 450 460 470
pF1KE6 HSQPSFCSSAKSGKHSDPVWQVKWQKDDMDQNLNFFSVSSDGRIVSWTLVKRKLVHIDVI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HSQPSFCSSAKSGKHSDPVWQVKWQKDDMDQNLNFFSVSSDGRIVSWTLVKRKLVHIDVI
430 440 450 460 470 480
480 490 500 510 520 530
pF1KE6 KLKVEGSTTEVPEGLQLHQVGCGTAFDFHKEIDYMFLVGTEEGKIYKCSKSYSSQFLDTY
:::::::::::::::::: :::::::::::::::::::::::::::::::::::::::::
XP_011 KLKVEGSTTEVPEGLQLHPVGCGTAFDFHKEIDYMFLVGTEEGKIYKCSKSYSSQFLDTY
490 500 510 520 530 540
540 550 560 570 580 590
pF1KE6 DAHNMSVDTVSWNPYHTKVFMSCSSDWTVKIWDHTIKTPMFIYDLNSAVGDVAWAPYSST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DAHNMSVDTVSWNPYHTKVFMSCSSDWTVKIWDHTIKTPMFIYDLNSAVGDVAWAPYSST
550 560 570 580 590 600
600 610 620 630 640 650
pF1KE6 VFAAVTTDGKAHIFDLAINKYEAICNQPVAAKKNRLTHVQFNLIHPIIIVGDDRGHIISL
::::::::::..
XP_011 VFAAVTTDGKGQAIQGPAKRGIIHPMRLQGGNRAVHLGGESTLGDEMPWSSYFLCCMVES
610 620 630 640 650 660
>>XP_006716821 (OMIM: 244400,604366) PREDICTED: dynein i (522 aa)
initn: 3502 init1: 3502 opt: 3502 Z-score: 2908.9 bits: 548.3 E(85289): 2.7e-155
Smith-Waterman score: 3502; 99.6% identity (99.6% similar) in 522 aa overlap (178-699:1-522)
150 160 170 180 190 200
pF1KE6 EEPKELETEPGSQTDVPAAGAAEKVTEEELMTPKQPKERKLTNQFNFSERASQTCNNPVR
:::::::::::::::::::::::: :::::
XP_006 MTPKQPKERKLTNQFNFSERASQTYNNPVR
10 20 30
210 220 230 240 250 260
pF1KE6 DRECQTEPPPRTNFSATANQWEIYDAYVEELEKQEKTKEKEKAKTPVAKKSGKMAMRKLT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 DRECQTEPPPRTNFSATANQWEIYDAYVEELEKQEKTKEKEKAKTPVAKKSGKMAMRKLT
40 50 60 70 80 90
270 280 290 300 310 320
pF1KE6 SMESQTDDLIKLSQAAKIMERMVNQNTYDDIAQDFKYYDDAADEYRDQVGTLLPLWKFQN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SMESQTDDLIKLSQAAKIMERMVNQNTYDDIAQDFKYYDDAADEYRDQVGTLLPLWKFQN
100 110 120 130 140 150
330 340 350 360 370 380
pF1KE6 DKAKRLSVTALCWNPKYRDLFAVGYGSYDFMKQSRGMLLLYSLKNPSFPEYMFSSNSGVM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 DKAKRLSVTALCWNPKYRDLFAVGYGSYDFMKQSRGMLLLYSLKNPSFPEYMFSSNSGVM
160 170 180 190 200 210
390 400 410 420 430 440
pF1KE6 CLDIHVDHPYLVAVGHYDGNVAIYNLKKPHSQPSFCSSAKSGKHSDPVWQVKWQKDDMDQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 CLDIHVDHPYLVAVGHYDGNVAIYNLKKPHSQPSFCSSAKSGKHSDPVWQVKWQKDDMDQ
220 230 240 250 260 270
450 460 470 480 490 500
pF1KE6 NLNFFSVSSDGRIVSWTLVKRKLVHIDVIKLKVEGSTTEVPEGLQLHQVGCGTAFDFHKE
::::::::::::::::::::::::::::::::::::::::::::::: ::::::::::::
XP_006 NLNFFSVSSDGRIVSWTLVKRKLVHIDVIKLKVEGSTTEVPEGLQLHPVGCGTAFDFHKE
280 290 300 310 320 330
510 520 530 540 550 560
pF1KE6 IDYMFLVGTEEGKIYKCSKSYSSQFLDTYDAHNMSVDTVSWNPYHTKVFMSCSSDWTVKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 IDYMFLVGTEEGKIYKCSKSYSSQFLDTYDAHNMSVDTVSWNPYHTKVFMSCSSDWTVKI
340 350 360 370 380 390
570 580 590 600 610 620
pF1KE6 WDHTIKTPMFIYDLNSAVGDVAWAPYSSTVFAAVTTDGKAHIFDLAINKYEAICNQPVAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 WDHTIKTPMFIYDLNSAVGDVAWAPYSSTVFAAVTTDGKAHIFDLAINKYEAICNQPVAA
400 410 420 430 440 450
630 640 650 660 670 680
pF1KE6 KKNRLTHVQFNLIHPIIIVGDDRGHIISLKLSPNLRKMPKEKKGQEVQKGPAVEIAKLDK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 KKNRLTHVQFNLIHPIIIVGDDRGHIISLKLSPNLRKMPKEKKGQEVQKGPAVEIAKLDK
460 470 480 490 500 510
690
pF1KE6 LLNLVREVKIKT
::::::::::::
XP_006 LLNLVREVKIKT
520
>>XP_011516151 (OMIM: 244400,604366) PREDICTED: dynein i (546 aa)
initn: 2621 init1: 2621 opt: 3462 Z-score: 2875.6 bits: 542.2 E(85289): 2e-153
Smith-Waterman score: 3462; 98.7% identity (98.9% similar) in 527 aa overlap (1-523:1-527)
10 20 30 40 50 60
pF1KE6 MIPASAKSPHKQPHKQSISIGRGTRKRDEDSGTEVGEGTDEWAQSKATVRPPDQLELTDA
:::::::.::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MIPASAKAPHKQPHKQSISIGRGTRKRDEDSGTEVGEGTDEWAQSKATVRPPDQLELTDA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 ELKEEFTRILTANNPHAPQNIVRYSFKEGTYKPIGFVNQLAVHYTQVGNLIPKDSDEGRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ELKEEFTRILTANNPHAPQNIVRYSFKEGTYKPIGFVNQLAVHYTQVGNLIPKDSDEGRR
70 80 90 100 110 120
130 140 150 160 170
pF1KE6 QHYRDELVA----GSQESVKVISETGNLEEDEEPKELETEPGSQTDVPAAGAAEKVTEEE
::::::::: :::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QHYRDELVAVSYQGSQESVKVISETGNLEEDEEPKELETEPGSQTDVPAAGAAEKVTEEE
130 140 150 160 170 180
180 190 200 210 220 230
pF1KE6 LMTPKQPKERKLTNQFNFSERASQTCNNPVRDRECQTEPPPRTNFSATANQWEIYDAYVE
::::::::::::::::::::::::: ::::::::::::::::::::::::::::::::::
XP_011 LMTPKQPKERKLTNQFNFSERASQTYNNPVRDRECQTEPPPRTNFSATANQWEIYDAYVE
190 200 210 220 230 240
240 250 260 270 280 290
pF1KE6 ELEKQEKTKEKEKAKTPVAKKSGKMAMRKLTSMESQTDDLIKLSQAAKIMERMVNQNTYD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ELEKQEKTKEKEKAKTPVAKKSGKMAMRKLTSMESQTDDLIKLSQAAKIMERMVNQNTYD
250 260 270 280 290 300
300 310 320 330 340 350
pF1KE6 DIAQDFKYYDDAADEYRDQVGTLLPLWKFQNDKAKRLSVTALCWNPKYRDLFAVGYGSYD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DIAQDFKYYDDAADEYRDQVGTLLPLWKFQNDKAKRLSVTALCWNPKYRDLFAVGYGSYD
310 320 330 340 350 360
360 370 380 390 400 410
pF1KE6 FMKQSRGMLLLYSLKNPSFPEYMFSSNSGVMCLDIHVDHPYLVAVGHYDGNVAIYNLKKP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FMKQSRGMLLLYSLKNPSFPEYMFSSNSGVMCLDIHVDHPYLVAVGHYDGNVAIYNLKKP
370 380 390 400 410 420
420 430 440 450 460 470
pF1KE6 HSQPSFCSSAKSGKHSDPVWQVKWQKDDMDQNLNFFSVSSDGRIVSWTLVKRKLVHIDVI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HSQPSFCSSAKSGKHSDPVWQVKWQKDDMDQNLNFFSVSSDGRIVSWTLVKRKLVHIDVI
430 440 450 460 470 480
480 490 500 510 520 530
pF1KE6 KLKVEGSTTEVPEGLQLHQVGCGTAFDFHKEIDYMFLVGTEEGKIYKCSKSYSSQFLDTY
:::::::::::::::::: ::::::::::::::::::::::::::::
XP_011 KLKVEGSTTEVPEGLQLHPVGCGTAFDFHKEIDYMFLVGTEEGKIYKLRLDSEDLGPHHQ
490 500 510 520 530 540
540 550 560 570 580 590
pF1KE6 DAHNMSVDTVSWNPYHTKVFMSCSSDWTVKIWDHTIKTPMFIYDLNSAVGDVAWAPYSST
XP_011 DPDVHL
>>XP_016870114 (OMIM: 244400,604366) PREDICTED: dynein i (613 aa)
initn: 2912 init1: 2912 opt: 2918 Z-score: 2425.1 bits: 459.0 E(85289): 2.4e-128
Smith-Waterman score: 3906; 87.4% identity (87.6% similar) in 699 aa overlap (1-699:1-613)
10 20 30 40 50 60
pF1KE6 MIPASAKSPHKQPHKQSISIGRGTRKRDEDSGTEVGEGTDEWAQSKATVRPPDQLELTDA
:::::::.::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MIPASAKAPHKQPHKQSISIGRGTRKRDEDSGTEVGEGTDEWAQSKATVRPPDQLELTDA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 ELKEEFTRILTANNPHAPQNIVRYSFKEGTYKPIGFVNQLAVHYTQVGNLIPKDSDEGRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ELKEEFTRILTANNPHAPQNIVRYSFKEGTYKPIGFVNQLAVHYTQVGNLIPKDSDEGRR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 QHYRDELVAGSQESVKVISETGNLEEDEEPKELETEPGSQTDVPAAGAAEKVTEEELMTP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QHYRDELVAGSQESVKVISETGNLEEDEEPKELETEPGSQTDVPAAGAAEKVTEEELMTP
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE6 KQPKERKLTNQFNFSERASQTCNNPVRDRECQTEPPPRTNFSATANQWEIYDAYVEELEK
::::::::::::::::::::: ::::::::::::::::::::::::::::::::::::::
XP_016 KQPKERKLTNQFNFSERASQTYNNPVRDRECQTEPPPRTNFSATANQWEIYDAYVEELEK
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE6 QEKTKEKEKAKTPVAKKSGKMAMRKLTSMESQTDDLIKLSQAAKIMERMVNQNTYDDIAQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QEKTKEKEKAKTPVAKKSGKMAMRKLTSMESQTDDLIKLSQAAKIMERMVNQNTYDDIAQ
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE6 DFKYYDDAADEYRDQVGTLLPLWKFQNDKAKRLSVTALCWNPKYRDLFAVGYGSYDFMKQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DFKYYDDAADEYRDQVGTLLPLWKFQNDKAKRLSVTALCWNPKYRDLFAVGYGSYDFMKQ
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE6 SRGMLLLYSLKNPSFPEYMFSSNSGVMCLDIHVDHPYLVAVGHYDGNVAIYNLKKPHSQP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SRGMLLLYSLKNPSFPEYMFSSNSGVMCLDIHVDHPYLVAVGHYDGNVAIYNLKKPHSQP
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE6 SFCSSAKSGKHSDPVWQVKWQKDDMDQNLNFFSVSSDGRIVSWTLVKRKLVHIDVIKLKV
:::::::::::::::::
XP_016 SFCSSAKSGKHSDPVWQ-------------------------------------------
430
490 500 510 520 530 540
pF1KE6 EGSTTEVPEGLQLHQVGCGTAFDFHKEIDYMFLVGTEEGKIYKCSKSYSSQFLDTYDAHN
:::::::::::::::::
XP_016 -------------------------------------------CSKSYSSQFLDTYDAHN
440 450
550 560 570 580 590 600
pF1KE6 MSVDTVSWNPYHTKVFMSCSSDWTVKIWDHTIKTPMFIYDLNSAVGDVAWAPYSSTVFAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MSVDTVSWNPYHTKVFMSCSSDWTVKIWDHTIKTPMFIYDLNSAVGDVAWAPYSSTVFAA
460 470 480 490 500 510
610 620 630 640 650 660
pF1KE6 VTTDGKAHIFDLAINKYEAICNQPVAAKKNRLTHVQFNLIHPIIIVGDDRGHIISLKLSP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VTTDGKAHIFDLAINKYEAICNQPVAAKKNRLTHVQFNLIHPIIIVGDDRGHIISLKLSP
520 530 540 550 560 570
670 680 690
pF1KE6 NLRKMPKEKKGQEVQKGPAVEIAKLDKLLNLVREVKIKT
:::::::::::::::::::::::::::::::::::::::
XP_016 NLRKMPKEKKGQEVQKGPAVEIAKLDKLLNLVREVKIKT
580 590 600 610
>>XP_011516152 (OMIM: 244400,604366) PREDICTED: dynein i (477 aa)
initn: 2053 init1: 2053 opt: 2911 Z-score: 2420.8 bits: 457.8 E(85289): 4.2e-128
Smith-Waterman score: 2911; 95.9% identity (97.4% similar) in 459 aa overlap (1-455:1-458)
10 20 30 40 50 60
pF1KE6 MIPASAKSPHKQPHKQSISIGRGTRKRDEDSGTEVGEGTDEWAQSKATVRPPDQLELTDA
:::::::.::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MIPASAKAPHKQPHKQSISIGRGTRKRDEDSGTEVGEGTDEWAQSKATVRPPDQLELTDA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 ELKEEFTRILTANNPHAPQNIVRYSFKEGTYKPIGFVNQLAVHYTQVGNLIPKDSDEGRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ELKEEFTRILTANNPHAPQNIVRYSFKEGTYKPIGFVNQLAVHYTQVGNLIPKDSDEGRR
70 80 90 100 110 120
130 140 150 160 170
pF1KE6 QHYRDELVA----GSQESVKVISETGNLEEDEEPKELETEPGSQTDVPAAGAAEKVTEEE
::::::::: :::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QHYRDELVAVSYQGSQESVKVISETGNLEEDEEPKELETEPGSQTDVPAAGAAEKVTEEE
130 140 150 160 170 180
180 190 200 210 220 230
pF1KE6 LMTPKQPKERKLTNQFNFSERASQTCNNPVRDRECQTEPPPRTNFSATANQWEIYDAYVE
::::::::::::::::::::::::: ::::::::::::::::::::::::::::::::::
XP_011 LMTPKQPKERKLTNQFNFSERASQTYNNPVRDRECQTEPPPRTNFSATANQWEIYDAYVE
190 200 210 220 230 240
240 250 260 270 280 290
pF1KE6 ELEKQEKTKEKEKAKTPVAKKSGKMAMRKLTSMESQTDDLIKLSQAAKIMERMVNQNTYD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ELEKQEKTKEKEKAKTPVAKKSGKMAMRKLTSMESQTDDLIKLSQAAKIMERMVNQNTYD
250 260 270 280 290 300
300 310 320 330 340 350
pF1KE6 DIAQDFKYYDDAADEYRDQVGTLLPLWKFQNDKAKRLSVTALCWNPKYRDLFAVGYGSYD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DIAQDFKYYDDAADEYRDQVGTLLPLWKFQNDKAKRLSVTALCWNPKYRDLFAVGYGSYD
310 320 330 340 350 360
360 370 380 390 400 410
pF1KE6 FMKQSRGMLLLYSLKNPSFPEYMFSSNSGVMCLDIHVDHPYLVAVGHYDGNVAIYNLKKP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FMKQSRGMLLLYSLKNPSFPEYMFSSNSGVMCLDIHVDHPYLVAVGHYDGNVAIYNLKKP
370 380 390 400 410 420
420 430 440 450 460 470
pF1KE6 HSQPSFCSSAKSGKHSDPVWQVKWQKDDMDQNLNFFSVSSDGRIVSWTLVKRKLVHIDVI
::::::::::::::::::::: :. :. :....::
XP_011 HSQPSFCSSAKSGKHSDPVWQ-DWEDLRMNFCLKLLKVSGLIRQQWDSVFSSFTSLLP
430 440 450 460 470
480 490 500 510 520 530
pF1KE6 KLKVEGSTTEVPEGLQLHQVGCGTAFDFHKEIDYMFLVGTEEGKIYKCSKSYSSQFLDTY
>>XP_011516150 (OMIM: 244400,604366) PREDICTED: dynein i (617 aa)
initn: 2053 init1: 2053 opt: 2900 Z-score: 2410.2 bits: 456.3 E(85289): 1.6e-127
Smith-Waterman score: 3888; 86.9% identity (87.1% similar) in 703 aa overlap (1-699:1-617)
10 20 30 40 50 60
pF1KE6 MIPASAKSPHKQPHKQSISIGRGTRKRDEDSGTEVGEGTDEWAQSKATVRPPDQLELTDA
:::::::.::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MIPASAKAPHKQPHKQSISIGRGTRKRDEDSGTEVGEGTDEWAQSKATVRPPDQLELTDA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 ELKEEFTRILTANNPHAPQNIVRYSFKEGTYKPIGFVNQLAVHYTQVGNLIPKDSDEGRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ELKEEFTRILTANNPHAPQNIVRYSFKEGTYKPIGFVNQLAVHYTQVGNLIPKDSDEGRR
70 80 90 100 110 120
130 140 150 160 170
pF1KE6 QHYRDELVA----GSQESVKVISETGNLEEDEEPKELETEPGSQTDVPAAGAAEKVTEEE
::::::::: :::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QHYRDELVAVSYQGSQESVKVISETGNLEEDEEPKELETEPGSQTDVPAAGAAEKVTEEE
130 140 150 160 170 180
180 190 200 210 220 230
pF1KE6 LMTPKQPKERKLTNQFNFSERASQTCNNPVRDRECQTEPPPRTNFSATANQWEIYDAYVE
::::::::::::::::::::::::: ::::::::::::::::::::::::::::::::::
XP_011 LMTPKQPKERKLTNQFNFSERASQTYNNPVRDRECQTEPPPRTNFSATANQWEIYDAYVE
190 200 210 220 230 240
240 250 260 270 280 290
pF1KE6 ELEKQEKTKEKEKAKTPVAKKSGKMAMRKLTSMESQTDDLIKLSQAAKIMERMVNQNTYD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ELEKQEKTKEKEKAKTPVAKKSGKMAMRKLTSMESQTDDLIKLSQAAKIMERMVNQNTYD
250 260 270 280 290 300
300 310 320 330 340 350
pF1KE6 DIAQDFKYYDDAADEYRDQVGTLLPLWKFQNDKAKRLSVTALCWNPKYRDLFAVGYGSYD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DIAQDFKYYDDAADEYRDQVGTLLPLWKFQNDKAKRLSVTALCWNPKYRDLFAVGYGSYD
310 320 330 340 350 360
360 370 380 390 400 410
pF1KE6 FMKQSRGMLLLYSLKNPSFPEYMFSSNSGVMCLDIHVDHPYLVAVGHYDGNVAIYNLKKP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FMKQSRGMLLLYSLKNPSFPEYMFSSNSGVMCLDIHVDHPYLVAVGHYDGNVAIYNLKKP
370 380 390 400 410 420
420 430 440 450 460 470
pF1KE6 HSQPSFCSSAKSGKHSDPVWQVKWQKDDMDQNLNFFSVSSDGRIVSWTLVKRKLVHIDVI
:::::::::::::::::::::
XP_011 HSQPSFCSSAKSGKHSDPVWQ---------------------------------------
430 440
480 490 500 510 520 530
pF1KE6 KLKVEGSTTEVPEGLQLHQVGCGTAFDFHKEIDYMFLVGTEEGKIYKCSKSYSSQFLDTY
:::::::::::::
XP_011 -----------------------------------------------CSKSYSSQFLDTY
450
540 550 560 570 580 590
pF1KE6 DAHNMSVDTVSWNPYHTKVFMSCSSDWTVKIWDHTIKTPMFIYDLNSAVGDVAWAPYSST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DAHNMSVDTVSWNPYHTKVFMSCSSDWTVKIWDHTIKTPMFIYDLNSAVGDVAWAPYSST
460 470 480 490 500 510
600 610 620 630 640 650
pF1KE6 VFAAVTTDGKAHIFDLAINKYEAICNQPVAAKKNRLTHVQFNLIHPIIIVGDDRGHIISL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VFAAVTTDGKAHIFDLAINKYEAICNQPVAAKKNRLTHVQFNLIHPIIIVGDDRGHIISL
520 530 540 550 560 570
660 670 680 690
pF1KE6 KLSPNLRKMPKEKKGQEVQKGPAVEIAKLDKLLNLVREVKIKT
:::::::::::::::::::::::::::::::::::::::::::
XP_011 KLSPNLRKMPKEKKGQEVQKGPAVEIAKLDKLLNLVREVKIKT
580 590 600 610
>>NP_075462 (OMIM: 605483,612444) dynein intermediate ch (605 aa)
initn: 212 init1: 77 opt: 486 Z-score: 414.4 bits: 86.9 E(85289): 2.4e-16
Smith-Waterman score: 486; 23.5% identity (57.6% similar) in 502 aa overlap (184-670:10-493)
160 170 180 190 200
pF1KE6 ETEPGSQTDVPAAGAAEKVTEEELMTPKQPKERKLTNQFNFSERASQTC----NNPVRDR
:. .. .: :::.: .. :: .
NP_075 MEIVYVYVKKRSEFGKQCNFSDRQAELNIDIMPNPELAE
10 20 30
210 220 230 240 250 260
pF1KE6 ECQTEPPPRTNFSATANQWEIYDAYVEELEKQEKTKEKEKAKTP--VAKKSGKMAMRKLT
. . : :... . .. : ..: :..: . . .. .. : : ....:
NP_075 QFVERNPVDTGIQCSISMSE-HEANSERFEMETRGVNHVEGGWPKDVNPLELEQTIRFRK
40 50 60 70 80 90
270 280 290 300 310 320
pF1KE6 SMESQTDDLIKLSQAAKIMERMVNQNTYDDIAQDFKYYDDAADEYRDQVGTLLPLWKFQN
..:.. . . . : ..:::. ..::. :: ... . :. : : .. . . :..
NP_075 KVEKDENYVNAIMQLGSIMEHCIKQNNAIDIYEEY-FNDEEAMEVMEEDPSAKTINVFRD
100 110 120 130 140 150
330 340 350 360 370 380
pF1KE6 DKAKRLSVTALCWNPKYRDLFAVGYGSYDFMKQSRGML---LLYSLKNPSFPEYMFSSNS
. . ..: : :.: .::.:. ::.. :: ...:.::. :: .. .:
NP_075 PQEIKRAATHLSWHPDGNRKLAVAYSCLDFQRAPVGMSSDSYIWDLENPNKPELALKPSS
160 170 180 190 200 210
390 400 410 420 430 440
pF1KE6 GVMCLDIHVDHPYLVAVGHYDGNVAIYNLKKPHSQPSFCSSAKSGKHSDPVWQVKWQKDD
.. :... ... : :.:..: .. .: : . :. .:. : :::. . : ..
NP_075 PLVTLEFNPKDSHVLLGGCYNGQIACWDTRKG-SLVAELSTIESS-HRDPVYGTIWLQSK
220 230 240 250 260 270
450 460 470 480 490 500
pF1KE6 MDQNLNFFSVSSDGRIVSWTLVKRKLVH-IDVIKLKVEGSTTEVPEGLQLHQVGCGTAFD
. . ::.:.::... : . ::. . .:. : .. . ::... . ...
NP_075 --TGTECFSASTDGQVMWWDI--RKMSEPTEVVIL-------DITKKEQLENALGAISLE
280 290 300 310 320
510 520 530 540 550 560
pF1KE6 FHKEIDYMFLVGTEEGKIYKCS---KSYSSQFLDTYDAHNMSVDTVSWNPYHTKVFMSCS
:.. . :.::::.: . .:. :. . ... :. .:. . ... ::.. : :.. .
NP_075 FESTLPTKFMVGTEQGIVISCNRKAKTSAEKIVCTFPGHHGPIYALQRNPFYPKNFLTVG
330 340 350 360 370 380
570 580 590 600 610
pF1KE6 SDWTVKIW--DHTIKTPMFIYDLNSAVGDVAWAPYSSTVFAAVTTDGKAHIFDLAINKYE
:::..:: : .. :. . . :.::.: ::: .. :: :.:. ... .
NP_075 -DWTARIWSEDSRESSIMWTKYHMAYLTDAAWSPVRPTVFFTTRMDGTLDIWDFMFEQCD
390 400 410 420 430 440
620 630 640 650 660 670
pF1KE6 AICNQPVAAKKNRLTHVQFNLIHPIIIVGDDRGHIISLKLSPNLRKMPKEKKGQEVQKGP
. : . .:: : .: :.. : :..::.: . ...:
NP_075 PTLSLKVCDEALFCLRVQDNGC--LIACGSQLGTTTLLEVSPGLSTLQRNEKNVASSMFE
450 460 470 480 490 500
680 690
pF1KE6 AVEIAKLDKLLNLVREVKIKT
NP_075 RETRREKILEARHREMRLKEKGKAEGRDEEQTDEELAVDLEALVSKAEEEFFDIIFAELK
510 520 530 540 550 560
699 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Nov 8 15:43:10 2016 done: Tue Nov 8 15:43:11 2016
Total Scan time: 8.750 Total Display time: 0.160
Function used was FASTA [36.3.4 Apr, 2011]