Result of FASTA (omim) for
pFN21AE6710
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE6710, 692 aa
1>>>pF1KE6710 692 - 692 aa - 692 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 4.7215+/-0.000368; mu= 23.9231+/- 0.023
mean_var=82.8657+/-16.303, 0's: 0 Z-trim(115.8): 79 B-trim: 726 in 1/50
Lambda= 0.140892
statistics sampled from 26352 (26447) to 26352 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.655), E-opt: 0.2 (0.31), width: 16
Scan time: 11.970
The best scores are: opt bits E(85289)
NP_001138516 (OMIM: 612435) solute carrier organic ( 692) 4670 959.5 0
XP_005254946 (OMIM: 612435) PREDICTED: solute carr ( 697) 4506 926.2 0
NP_037404 (OMIM: 612435) solute carrier organic an ( 710) 4496 924.1 0
XP_011519758 (OMIM: 612435) PREDICTED: solute carr ( 652) 4101 843.8 0
XP_005254948 (OMIM: 612435) PREDICTED: solute carr ( 595) 3751 772.6 0
XP_011519006 (OMIM: 613389) PREDICTED: solute carr ( 711) 1428 300.5 1.4e-80
NP_059131 (OMIM: 613389) solute carrier organic an ( 712) 1428 300.5 1.4e-80
XP_005253451 (OMIM: 613389) PREDICTED: solute carr ( 712) 1428 300.5 1.4e-80
NP_062818 (OMIM: 237450,605495) solute carrier org ( 702) 1395 293.8 1.5e-78
XP_011519005 (OMIM: 613389) PREDICTED: solute carr ( 729) 1392 293.2 2.3e-78
NP_001139418 (OMIM: 613389) solute carrier organic ( 730) 1392 293.2 2.3e-78
NP_006437 (OMIM: 237450,604843) solute carrier org ( 691) 1372 289.1 3.7e-77
XP_016874976 (OMIM: 613389) PREDICTED: solute carr ( 594) 1163 246.6 2.1e-64
XP_016874975 (OMIM: 613389) PREDICTED: solute carr ( 594) 1163 246.6 2.1e-64
NP_001139416 (OMIM: 613389) solute carrier organic ( 612) 1127 239.3 3.4e-62
XP_016874974 (OMIM: 613389) PREDICTED: solute carr ( 612) 1127 239.3 3.4e-62
XP_011519011 (OMIM: 613389) PREDICTED: solute carr ( 612) 1127 239.3 3.4e-62
XP_005253453 (OMIM: 613389) PREDICTED: solute carr ( 612) 1127 239.3 3.4e-62
XP_016874973 (OMIM: 613389) PREDICTED: solute carr ( 612) 1127 239.3 3.4e-62
NP_001139480 (OMIM: 613543) solute carrier organic ( 687) 1107 235.3 6.1e-61
XP_016869372 (OMIM: 613543) PREDICTED: solute carr ( 687) 1107 235.3 6.1e-61
NP_112220 (OMIM: 613543) solute carrier organic an ( 848) 1107 235.4 7e-61
XP_016874977 (OMIM: 613389) PREDICTED: solute carr ( 564) 1101 233.9 1.3e-60
XP_011519013 (OMIM: 613389) PREDICTED: solute carr ( 564) 1101 233.9 1.3e-60
XP_016874979 (OMIM: 613389) PREDICTED: solute carr ( 545) 1090 231.7 5.8e-60
XP_016874978 (OMIM: 613389) PREDICTED: solute carr ( 545) 1090 231.7 5.8e-60
XP_011519121 (OMIM: 602883) PREDICTED: solute carr ( 670) 1040 221.6 7.6e-57
XP_005253531 (OMIM: 602883) PREDICTED: solute carr ( 670) 1040 221.6 7.6e-57
NP_602307 (OMIM: 602883) solute carrier organic an ( 670) 1040 221.6 7.6e-57
XP_011519120 (OMIM: 602883) PREDICTED: solute carr ( 670) 1040 221.6 7.6e-57
NP_066580 (OMIM: 602883) solute carrier organic an ( 670) 1040 221.6 7.6e-57
XP_011519122 (OMIM: 602883) PREDICTED: solute carr ( 668) 1016 216.8 2.2e-55
XP_005253534 (OMIM: 602883) PREDICTED: solute carr ( 650) 1007 214.9 7.8e-55
XP_016875338 (OMIM: 602883) PREDICTED: solute carr ( 598) 996 212.6 3.5e-54
XP_016875339 (OMIM: 602883) PREDICTED: solute carr ( 578) 963 205.9 3.5e-52
XP_016869373 (OMIM: 613543) PREDICTED: solute carr ( 554) 962 205.7 4e-52
NP_001138683 (OMIM: 604988) solute carrier organic ( 687) 792 171.2 1.2e-41
NP_009187 (OMIM: 604988) solute carrier organic an ( 709) 792 171.2 1.2e-41
XP_016872646 (OMIM: 604988) PREDICTED: solute carr ( 711) 792 171.3 1.2e-41
NP_005621 (OMIM: 601460,614441) solute carrier org ( 643) 746 161.9 7.2e-39
XP_011519123 (OMIM: 602883) PREDICTED: solute carr ( 362) 689 150.0 1.5e-35
XP_016869375 (OMIM: 613543) PREDICTED: solute carr ( 423) 676 147.4 1e-34
XP_016869374 (OMIM: 613543) PREDICTED: solute carr ( 544) 656 143.5 2.1e-33
XP_011541674 (OMIM: 609013) PREDICTED: solute carr ( 586) 638 139.9 2.7e-32
XP_011541672 (OMIM: 609013) PREDICTED: solute carr ( 636) 638 139.9 2.9e-32
NP_851322 (OMIM: 609013) solute carrier organic an ( 724) 638 140.0 3.2e-32
XP_011541455 (OMIM: 613365) PREDICTED: solute carr ( 445) 496 110.9 1.1e-23
XP_011541452 (OMIM: 613365) PREDICTED: solute carr ( 476) 496 110.9 1.2e-23
XP_011541450 (OMIM: 613365) PREDICTED: solute carr ( 640) 496 111.0 1.4e-23
NP_001275933 (OMIM: 613365) solute carrier organic ( 657) 496 111.0 1.4e-23
>>NP_001138516 (OMIM: 612435) solute carrier organic ani (692 aa)
initn: 4670 init1: 4670 opt: 4670 Z-score: 5129.1 bits: 959.5 E(85289): 0
Smith-Waterman score: 4670; 99.7% identity (99.9% similar) in 692 aa overlap (1-692:1-692)
10 20 30 40 50 60
pF1KE6 MQGKKPGGSSGGGRSGELQGDEAQRNKKKKKKVSCFSNIKIFLVSECALMLAQGTVGAYL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MQGKKPGGSSGGGRSGELQGDEAQRNKKKKKKVSCFSNIKIFLVSECALMLAQGTVGAYL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 VSVLTTLERRFNLQSADVGVIASSFEIGNLALILFVSYFGARGHRPRLIGCGGIVMALGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VSVLTTLERRFNLQSADVGVIASSFEIGNLALILFVSYFGARGHRPRLIGCGGIVMALGA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 LLSALPEFLTHQYKYEAGEIRWGAEGRDVCAANGSGGDEGPDPDLICLNRTATNMMYLLL
::::::::::::::::::::::::::::::::::::::::::::::: ::::::::::::
NP_001 LLSALPEFLTHQYKYEAGEIRWGAEGRDVCAANGSGGDEGPDPDLICRNRTATNMMYLLL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE6 IGAQVLLGIGATPVQPLGVSYIDDHVRRKDSSLYIGILFTMLVFGPACGFILGSFCTKIY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IGAQVLLGIGATPVQPLGVSYIDDHVRRKDSSLYIGILFTMLVFGPACGFILGSFCTKIY
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE6 VDAVFIDTSNLDITPDDPRWIGAWWGGFLLCGALLFFSSLLMFGFPQSLPPHSDPAMESE
:::::::::::::::::::::::::::::::::::::::::::::::::::::.::::::
NP_001 VDAVFIDTSNLDITPDDPRWIGAWWGGFLLCGALLFFSSLLMFGFPQSLPPHSEPAMESE
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE6 QAMLSEREYERPKPSNGVLRHPLEPDSSASCFQQLRVIPKVTKHLLSNPVFTCIILAACM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QAMLSEREYERPKPSNGVLRHPLEPDSSASCFQQLRVIPKVTKHLLSNPVFTCIILAACM
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE6 EIAVVAGFAAFLGKYLEQQFNLTTSSANQLLGMTAIPCACLGIFLGGLLVKKLSLSALGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EIAVVAGFAAFLGKYLEQQFNLTTSSANQLLGMTAIPCACLGIFLGGLLVKKLSLSALGA
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE6 IRMAMLVNLVSTACYVSFLFLGCDTGPVAGVTVPYGNSTAPGSALDPYSPCNNNCECQTD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IRMAMLVNLVSTACYVSFLFLGCDTGPVAGVTVPYGNSTAPGSALDPYSPCNNNCECQTD
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE6 SFTPVCGADGITYLSACFAGCNSTNLTGCACLTTVPAENATVVPGKCPSPGCQEAFLTFL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SFTPVCGADGITYLSACFAGCNSTNLTGCACLTTVPAENATVVPGKCPSPGCQEAFLTFL
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE6 CVMCICSLIGAMAQTPSVIILIRTVSPELKSYALGVLFLLLRLLGFIPPPLIFGAGIDST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CVMCICSLIGAMAQTPSVIILIRTVSPELKSYALGVLFLLLRLLGFIPPPLIFGAGIDST
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE6 CLFWSTFCGEQGACVLYDNVVYRYLYVSIAIALKSFAFILYTTTWQCLRKNYKRYIKNHE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CLFWSTFCGEQGACVLYDNVVYRYLYVSIAIALKSFAFILYTTTWQCLRKNYKRYIKNHE
610 620 630 640 650 660
670 680 690
pF1KE6 GGLSTSTEYQDIETEKTCPESHSPSEDSFVRS
::::::::::::::::::::::::::::::::
NP_001 GGLSTSTEYQDIETEKTCPESHSPSEDSFVRS
670 680 690
>>XP_005254946 (OMIM: 612435) PREDICTED: solute carrier (697 aa)
initn: 4533 init1: 4500 opt: 4506 Z-score: 4948.9 bits: 926.2 E(85289): 0
Smith-Waterman score: 4506; 97.9% identity (98.7% similar) in 681 aa overlap (1-678:1-681)
10 20 30 40 50 60
pF1KE6 MQGKKPGGSSGGGRSGELQGDEAQRNKKKKKKVSCFSNIKIFLVSECALMLAQGTVGAYL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MQGKKPGGSSGGGRSGELQGDEAQRNKKKKKKVSCFSNIKIFLVSECALMLAQGTVGAYL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 VSVLTTLERRFNLQSADVGVIASSFEIGNLALILFVSYFGARGHRPRLIGCGGIVMALGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VSVLTTLERRFNLQSADVGVIASSFEIGNLALILFVSYFGARGHRPRLIGCGGIVMALGA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 LLSALPEFLTHQYKYEAGEIRWGAEGRDVCAANGSGGDEGPDPDLICLNRTATNMMYLLL
::::::::::::::::::::::::::::::::::::::::::::::: ::::::::::::
XP_005 LLSALPEFLTHQYKYEAGEIRWGAEGRDVCAANGSGGDEGPDPDLICRNRTATNMMYLLL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE6 IGAQVLLGIGATPVQPLGVSYIDDHVRRKDSSLYIGILFTMLVFGPACGFILGSFCTKIY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IGAQVLLGIGATPVQPLGVSYIDDHVRRKDSSLYIGILFTMLVFGPACGFILGSFCTKIY
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE6 VDAVFIDTSNLDITPDDPRWIGAWWGGFLLCGALLFFSSLLMFGFPQSLPPHSDPAMESE
:::::::::::::::::::::::::::::::::::::::::::::::::::::.::::::
XP_005 VDAVFIDTSNLDITPDDPRWIGAWWGGFLLCGALLFFSSLLMFGFPQSLPPHSEPAMESE
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE6 QAMLSEREYERPKPSNGVLRHPLEPDSSASCFQQLRVIPKVTKHLLSNPVFTCIILAACM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 QAMLSEREYERPKPSNGVLRHPLEPDSSASCFQQLRVIPKVTKHLLSNPVFTCIILAACM
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE6 EIAVVAGFAAFLGKYLEQQFNLTTSSANQLLGMTAIPCACLGIFLGGLLVKKLSLSALGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EIAVVAGFAAFLGKYLEQQFNLTTSSANQLLGMTAIPCACLGIFLGGLLVKKLSLSALGA
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE6 IRMAMLVNLVSTACYVSFLFLGCDTGPVAGVTVPYGNSTAPGSALDPYSPCNNNCECQTD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 IRMAMLVNLVSTACYVSFLFLGCDTGPVAGVTVPYGNSTAPGSALDPYSPCNNNCECQTD
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE6 SFTPVCGADGITYLSACFAGCNSTNLTGCACLTTVPAENATVVPGKCPSPGCQEAFLTFL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SFTPVCGADGITYLSACFAGCNSTNLTGCACLTTVPAENATVVPGKCPSPGCQEAFLTFL
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE6 CVMCICSLIGAMAQTPSVIILIRTVSPELKSYALGVLFLLLRLLGFIPPPLIFGAGIDST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 CVMCICSLIGAMAQTPSVIILIRTVSPELKSYALGVLFLLLRLLGFIPPPLIFGAGIDST
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE6 CLFWSTFCGEQGACVLYDNVVYRYLYVSIAIALKSFAFILYTTTWQCLRKNYKRYIKNHE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 CLFWSTFCGEQGACVLYDNVVYRYLYVSIAIALKSFAFILYTTTWQCLRKNYKRYIKNHE
610 620 630 640 650 660
670 680 690
pF1KE6 GGLSTSTE---YQDIETEKTCPESHSPSEDSFVRS
:::::..: :. : .:
XP_005 GGLSTTSEPDRIQNKERMTSCGRVLEATCAAGPQSLL
670 680 690
>>NP_037404 (OMIM: 612435) solute carrier organic anion (710 aa)
initn: 4495 init1: 4495 opt: 4496 Z-score: 4937.8 bits: 924.1 E(85289): 0
Smith-Waterman score: 4496; 96.8% identity (98.3% similar) in 688 aa overlap (1-688:1-688)
10 20 30 40 50 60
pF1KE6 MQGKKPGGSSGGGRSGELQGDEAQRNKKKKKKVSCFSNIKIFLVSECALMLAQGTVGAYL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_037 MQGKKPGGSSGGGRSGELQGDEAQRNKKKKKKVSCFSNIKIFLVSECALMLAQGTVGAYL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 VSVLTTLERRFNLQSADVGVIASSFEIGNLALILFVSYFGARGHRPRLIGCGGIVMALGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_037 VSVLTTLERRFNLQSADVGVIASSFEIGNLALILFVSYFGARGHRPRLIGCGGIVMALGA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 LLSALPEFLTHQYKYEAGEIRWGAEGRDVCAANGSGGDEGPDPDLICLNRTATNMMYLLL
::::::::::::::::::::::::::::::::::::::::::::::: ::::::::::::
NP_037 LLSALPEFLTHQYKYEAGEIRWGAEGRDVCAANGSGGDEGPDPDLICRNRTATNMMYLLL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE6 IGAQVLLGIGATPVQPLGVSYIDDHVRRKDSSLYIGILFTMLVFGPACGFILGSFCTKIY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_037 IGAQVLLGIGATPVQPLGVSYIDDHVRRKDSSLYIGILFTMLVFGPACGFILGSFCTKIY
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE6 VDAVFIDTSNLDITPDDPRWIGAWWGGFLLCGALLFFSSLLMFGFPQSLPPHSDPAMESE
:::::::::::::::::::::::::::::::::::::::::::::::::::::.::::::
NP_037 VDAVFIDTSNLDITPDDPRWIGAWWGGFLLCGALLFFSSLLMFGFPQSLPPHSEPAMESE
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE6 QAMLSEREYERPKPSNGVLRHPLEPDSSASCFQQLRVIPKVTKHLLSNPVFTCIILAACM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_037 QAMLSEREYERPKPSNGVLRHPLEPDSSASCFQQLRVIPKVTKHLLSNPVFTCIILAACM
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE6 EIAVVAGFAAFLGKYLEQQFNLTTSSANQLLGMTAIPCACLGIFLGGLLVKKLSLSALGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_037 EIAVVAGFAAFLGKYLEQQFNLTTSSANQLLGMTAIPCACLGIFLGGLLVKKLSLSALGA
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE6 IRMAMLVNLVSTACYVSFLFLGCDTGPVAGVTVPYGNSTAPGSALDPYSPCNNNCECQTD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_037 IRMAMLVNLVSTACYVSFLFLGCDTGPVAGVTVPYGNSTAPGSALDPYSPCNNNCECQTD
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE6 SFTPVCGADGITYLSACFAGCNSTNLTGCACLTTVPAENATVVPGKCPSPGCQEAFLTFL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_037 SFTPVCGADGITYLSACFAGCNSTNLTGCACLTTVPAENATVVPGKCPSPGCQEAFLTFL
490 500 510 520 530 540
550 560 570 580 590 600
pF1KE6 CVMCICSLIGAMAQTPSVIILIRTVSPELKSYALGVLFLLLRLLGFIPPPLIFGAGIDST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_037 CVMCICSLIGAMAQTPSVIILIRTVSPELKSYALGVLFLLLRLLGFIPPPLIFGAGIDST
550 560 570 580 590 600
610 620 630 640 650 660
pF1KE6 CLFWSTFCGEQGACVLYDNVVYRYLYVSIAIALKSFAFILYTTTWQCLRKNYKRYIKNHE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_037 CLFWSTFCGEQGACVLYDNVVYRYLYVSIAIALKSFAFILYTTTWQCLRKNYKRYIKNHE
610 620 630 640 650 660
670 680 690
pF1KE6 GGLSTSTEYQDIETEKTCPESHSPSEDSFVRS
:::::: . . : . .. :....
NP_037 GGLSTSEFFASTLTLDNLGRDPVPANQTHRTKFIYNLEDHEWCENMESVL
670 680 690 700 710
>>XP_011519758 (OMIM: 612435) PREDICTED: solute carrier (652 aa)
initn: 4100 init1: 4100 opt: 4101 Z-score: 4504.3 bits: 843.8 E(85289): 0
Smith-Waterman score: 4101; 96.5% identity (98.1% similar) in 628 aa overlap (61-688:3-630)
40 50 60 70 80 90
pF1KE6 KKVSCFSNIKIFLVSECALMLAQGTVGAYLVSVLTTLERRFNLQSADVGVIASSFEIGNL
::::::::::::::::::::::::::::::
XP_011 MNVSVLTTLERRFNLQSADVGVIASSFEIGNL
10 20 30
100 110 120 130 140 150
pF1KE6 ALILFVSYFGARGHRPRLIGCGGIVMALGALLSALPEFLTHQYKYEAGEIRWGAEGRDVC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ALILFVSYFGARGHRPRLIGCGGIVMALGALLSALPEFLTHQYKYEAGEIRWGAEGRDVC
40 50 60 70 80 90
160 170 180 190 200 210
pF1KE6 AANGSGGDEGPDPDLICLNRTATNMMYLLLIGAQVLLGIGATPVQPLGVSYIDDHVRRKD
::::::::::::::::: ::::::::::::::::::::::::::::::::::::::::::
XP_011 AANGSGGDEGPDPDLICRNRTATNMMYLLLIGAQVLLGIGATPVQPLGVSYIDDHVRRKD
100 110 120 130 140 150
220 230 240 250 260 270
pF1KE6 SSLYIGILFTMLVFGPACGFILGSFCTKIYVDAVFIDTSNLDITPDDPRWIGAWWGGFLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SSLYIGILFTMLVFGPACGFILGSFCTKIYVDAVFIDTSNLDITPDDPRWIGAWWGGFLL
160 170 180 190 200 210
280 290 300 310 320 330
pF1KE6 CGALLFFSSLLMFGFPQSLPPHSDPAMESEQAMLSEREYERPKPSNGVLRHPLEPDSSAS
:::::::::::::::::::::::.::::::::::::::::::::::::::::::::::::
XP_011 CGALLFFSSLLMFGFPQSLPPHSEPAMESEQAMLSEREYERPKPSNGVLRHPLEPDSSAS
220 230 240 250 260 270
340 350 360 370 380 390
pF1KE6 CFQQLRVIPKVTKHLLSNPVFTCIILAACMEIAVVAGFAAFLGKYLEQQFNLTTSSANQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CFQQLRVIPKVTKHLLSNPVFTCIILAACMEIAVVAGFAAFLGKYLEQQFNLTTSSANQL
280 290 300 310 320 330
400 410 420 430 440 450
pF1KE6 LGMTAIPCACLGIFLGGLLVKKLSLSALGAIRMAMLVNLVSTACYVSFLFLGCDTGPVAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LGMTAIPCACLGIFLGGLLVKKLSLSALGAIRMAMLVNLVSTACYVSFLFLGCDTGPVAG
340 350 360 370 380 390
460 470 480 490 500 510
pF1KE6 VTVPYGNSTAPGSALDPYSPCNNNCECQTDSFTPVCGADGITYLSACFAGCNSTNLTGCA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VTVPYGNSTAPGSALDPYSPCNNNCECQTDSFTPVCGADGITYLSACFAGCNSTNLTGCA
400 410 420 430 440 450
520 530 540 550 560 570
pF1KE6 CLTTVPAENATVVPGKCPSPGCQEAFLTFLCVMCICSLIGAMAQTPSVIILIRTVSPELK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CLTTVPAENATVVPGKCPSPGCQEAFLTFLCVMCICSLIGAMAQTPSVIILIRTVSPELK
460 470 480 490 500 510
580 590 600 610 620 630
pF1KE6 SYALGVLFLLLRLLGFIPPPLIFGAGIDSTCLFWSTFCGEQGACVLYDNVVYRYLYVSIA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SYALGVLFLLLRLLGFIPPPLIFGAGIDSTCLFWSTFCGEQGACVLYDNVVYRYLYVSIA
520 530 540 550 560 570
640 650 660 670 680 690
pF1KE6 IALKSFAFILYTTTWQCLRKNYKRYIKNHEGGLSTSTEYQDIETEKTCPESHSPSEDSFV
:::::::::::::::::::::::::::::::::::: . . : . .. :....
XP_011 IALKSFAFILYTTTWQCLRKNYKRYIKNHEGGLSTSEFFASTLTLDNLGRDPVPANQTHR
580 590 600 610 620 630
pF1KE6 RS
XP_011 TKFIYNLEDHEWCENMESVL
640 650
>>XP_005254948 (OMIM: 612435) PREDICTED: solute carrier (595 aa)
initn: 3750 init1: 3750 opt: 3751 Z-score: 4120.3 bits: 772.6 E(85289): 0
Smith-Waterman score: 3751; 96.2% identity (97.9% similar) in 573 aa overlap (116-688:1-573)
90 100 110 120 130 140
pF1KE6 EIGNLALILFVSYFGARGHRPRLIGCGGIVMALGALLSALPEFLTHQYKYEAGEIRWGAE
::::::::::::::::::::::::::::::
XP_005 MALGALLSALPEFLTHQYKYEAGEIRWGAE
10 20 30
150 160 170 180 190 200
pF1KE6 GRDVCAANGSGGDEGPDPDLICLNRTATNMMYLLLIGAQVLLGIGATPVQPLGVSYIDDH
:::::::::::::::::::::: :::::::::::::::::::::::::::::::::::::
XP_005 GRDVCAANGSGGDEGPDPDLICRNRTATNMMYLLLIGAQVLLGIGATPVQPLGVSYIDDH
40 50 60 70 80 90
210 220 230 240 250 260
pF1KE6 VRRKDSSLYIGILFTMLVFGPACGFILGSFCTKIYVDAVFIDTSNLDITPDDPRWIGAWW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VRRKDSSLYIGILFTMLVFGPACGFILGSFCTKIYVDAVFIDTSNLDITPDDPRWIGAWW
100 110 120 130 140 150
270 280 290 300 310 320
pF1KE6 GGFLLCGALLFFSSLLMFGFPQSLPPHSDPAMESEQAMLSEREYERPKPSNGVLRHPLEP
::::::::::::::::::::::::::::.:::::::::::::::::::::::::::::::
XP_005 GGFLLCGALLFFSSLLMFGFPQSLPPHSEPAMESEQAMLSEREYERPKPSNGVLRHPLEP
160 170 180 190 200 210
330 340 350 360 370 380
pF1KE6 DSSASCFQQLRVIPKVTKHLLSNPVFTCIILAACMEIAVVAGFAAFLGKYLEQQFNLTTS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DSSASCFQQLRVIPKVTKHLLSNPVFTCIILAACMEIAVVAGFAAFLGKYLEQQFNLTTS
220 230 240 250 260 270
390 400 410 420 430 440
pF1KE6 SANQLLGMTAIPCACLGIFLGGLLVKKLSLSALGAIRMAMLVNLVSTACYVSFLFLGCDT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SANQLLGMTAIPCACLGIFLGGLLVKKLSLSALGAIRMAMLVNLVSTACYVSFLFLGCDT
280 290 300 310 320 330
450 460 470 480 490 500
pF1KE6 GPVAGVTVPYGNSTAPGSALDPYSPCNNNCECQTDSFTPVCGADGITYLSACFAGCNSTN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GPVAGVTVPYGNSTAPGSALDPYSPCNNNCECQTDSFTPVCGADGITYLSACFAGCNSTN
340 350 360 370 380 390
510 520 530 540 550 560
pF1KE6 LTGCACLTTVPAENATVVPGKCPSPGCQEAFLTFLCVMCICSLIGAMAQTPSVIILIRTV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LTGCACLTTVPAENATVVPGKCPSPGCQEAFLTFLCVMCICSLIGAMAQTPSVIILIRTV
400 410 420 430 440 450
570 580 590 600 610 620
pF1KE6 SPELKSYALGVLFLLLRLLGFIPPPLIFGAGIDSTCLFWSTFCGEQGACVLYDNVVYRYL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 SPELKSYALGVLFLLLRLLGFIPPPLIFGAGIDSTCLFWSTFCGEQGACVLYDNVVYRYL
460 470 480 490 500 510
630 640 650 660 670 680
pF1KE6 YVSIAIALKSFAFILYTTTWQCLRKNYKRYIKNHEGGLSTSTEYQDIETEKTCPESHSPS
::::::::::::::::::::::::::::::::::::::::: . . : . .. :.
XP_005 YVSIAIALKSFAFILYTTTWQCLRKNYKRYIKNHEGGLSTSEFFASTLTLDNLGRDPVPA
520 530 540 550 560 570
690
pF1KE6 EDSFVRS
...
XP_005 NQTHRTKFIYNLEDHEWCENMESVL
580 590
>>XP_011519006 (OMIM: 613389) PREDICTED: solute carrier (711 aa)
initn: 1382 init1: 393 opt: 1428 Z-score: 1567.5 bits: 300.5 E(85289): 1.4e-80
Smith-Waterman score: 1434; 34.8% identity (67.2% similar) in 676 aa overlap (30-670:33-688)
10 20 30 40 50
pF1KE6 MQGKKPGGSSGGGRSGELQGDEAQRNKKKKKKVSCFSNIKIFLVSECALMLAQGTVGAY
..: : ...:.:: . ...:.. . .:
XP_011 TSSKENIQLFCKTSVQPVGRPSFKTEYPSSEEKQPCCGELKVFLCALSFVYFAKALAEGY
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE6 LVSVLTTLERRFNLQSADVGVIASSFEIGNLALILFVSYFGARGHRPRLIGCGGIVMALG
: :..: .::::.. :. :::: .::::::: .: :::::::. :::..:: : ..:..:
XP_011 LKSTITQIERRFDIPSSLVGVIDGSFEIGNLLVITFVSYFGAKLHRPKIIGAGCVIMGVG
70 80 90 100 110 120
120 130 140 150 160
pF1KE6 ALLSALPEFLTHQYKYEAGEIRWGAEGRDV-----CAANGSGGD-----EGPDPDLI--C
.:: :.:.:. .::::: :.. . .. : ..:. : . :
XP_011 TLLIAMPQFFMEQYKYE----RYSPSSNSTLSISPCLLESSSQLPVSVMEKSKSKISNEC
130 140 150 160 170
170 180 190 200 210 220
pF1KE6 LNRTATNMMYLLLIGAQVLLGIGATPVQPLGVSYIDDHVRRKDSSLYIGILFTMLVFGPA
:...: ...: ..: ::: ::.::::..:.:: . . ....::: . :. ..::
XP_011 EVDTSSSMWIYVFLG-NLLRGIGETPIQPLGIAYLDDFASEDNAAFYIGCVQTVAIIGPI
180 190 200 210 220 230
230 240 250 260 270 280
pF1KE6 CGFILGSFCTKIYVDAVFIDTSNLDITPDDPRWIGAWWGGFLLCGALLFFSSLLMFGFPQ
::.:::.:.:.::: :.. ... ::: ::.:.:::: :.:. : . ..... .. .:.
XP_011 FGFLLGSLCAKLYVDIGFVNLDHITITPKDPQWVGAWWLGYLIAGIISLLAAVPFWYLPK
240 250 260 270 280 290
290 300 310 320 330 340
pF1KE6 SLP---PHSDPAMESEQAML---SEREYERPKPSNGVLRHPLEPDSSASCFQQLRVIPKV
::: . : ::.. . .. .:. :. : :. ... : .
XP_011 SLPRSQSREDSNSSSEKSKFIIDDHTDYQTPQGEN------------AKIMEMARDFLPS
300 310 320 330 340
350 360 370 380 390 400
pF1KE6 TKHLLSNPVFTCIILAACMEIAVVAGFAAFLGKYLEQQFNLTTSSANQLLGMTAIPCACL
:.:..:::. . .. ... . :.... ::.:::.. ..: :: ..:. :: . :
XP_011 LKNLFGNPVYFLYLCTSTVQFNSLFGMVTYKPKYIEQQYGQSSSRANFVIGLINIPAVAL
350 360 370 380 390 400
410 420 430 440 450 460
pF1KE6 GIFLGGLLVKKLSLSALGAIRMAMLVNLVSTACYVSFLFLGCDTGPVAGVTVPYGNSTAP
::: ::...::. .:. :: .. . .. . ..:.. :::... :::.:: : ..: :
XP_011 GIFSGGIVMKKFRISVCGAAKLYLGSSVFGYLLFLSLFALGCENSDVAGLTVSY-QGTKP
410 420 430 440 450 460
470 480 490 500 510
pF1KE6 GSALDP--YSPCNNNCECQTDSFTPVCGADGITYLSACFAGCNSTNLTG-------CACL
: . .: ::. :.:. .. :.:: .::::.:::.:::...: .: :.:.
XP_011 VSYHERALFSDCNSRCKCSETKWEPMCGENGITYVSACLAGCQTSNRSGKNIIFYNCTCV
470 480 490 500 510 520
520 530 540 550 560
pF1KE6 TTVPAE--NATVVPGKCPSP-GCQEAFLTFLCVMCICSLIGAMAQTPSVIILIRTVSPEL
. .. :.. . :.: . :: . :: :: . : : ... :. :.:.: ..:.:
XP_011 GIAASKSGNSSGIVGRCQKDNGCPQMFLYFLVISVITSYTLSLGGIPGYILLLRCIKPQL
530 540 550 560 570 580
570 580 590 600 610 620
pF1KE6 KSYALGVLFLLLRLLGFIPPPLIFGAGIDSTCLFWS-TFCGEQGACVLYDNVVYRYLYVS
::.:::. : .:.:: :: :. ::. ::..:: :. :: .:.: :::. :.:..:..
XP_011 KSFALGIYTLAIRVLG-IPAPVYFGVLIDTSCLKWGFKRCGSRGSCRLYDSNVFRHIYLG
590 600 610 620 630 640
630 640 650 660 670 680
pF1KE6 IAIALKSFAFILYTTTWQCLRKNY----KRYIKNHEGGLSTSTEYQDIETEKTCPESHSP
... : . ...: .. :.::: . .: ..: . .::..:
XP_011 LTVILGTVSILLSIAVLFILKKNYVSKHRSFITKRERTM-VSTRFQKENYTTSDHLLQPN
650 660 670 680 690 700
690
pF1KE6 SEDSFVRS
XP_011 YWPGKETQL
710
>>NP_059131 (OMIM: 613389) solute carrier organic anion (712 aa)
initn: 1452 init1: 393 opt: 1428 Z-score: 1567.5 bits: 300.5 E(85289): 1.4e-80
Smith-Waterman score: 1434; 34.6% identity (67.2% similar) in 676 aa overlap (30-670:33-689)
10 20 30 40 50
pF1KE6 MQGKKPGGSSGGGRSGELQGDEAQRNKKKKKKVSCFSNIKIFLVSECALMLAQGTVGAY
..: : ...:.:: . ...:.. . .:
NP_059 TSSKENIQLFCKTSVQPVGRPSFKTEYPSSEEKQPCCGELKVFLCALSFVYFAKALAEGY
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE6 LVSVLTTLERRFNLQSADVGVIASSFEIGNLALILFVSYFGARGHRPRLIGCGGIVMALG
: :..: .::::.. :. :::: .::::::: .: :::::::. :::..:: : ..:..:
NP_059 LKSTITQIERRFDIPSSLVGVIDGSFEIGNLLVITFVSYFGAKLHRPKIIGAGCVIMGVG
70 80 90 100 110 120
120 130 140 150 160
pF1KE6 ALLSALPEFLTHQYKYEAGEIRWGAEGRDV-----CAANGSGGD-----EGPDPDLI--C
.:: :.:.:. .::::: :.. . .. : ..:. : . :
NP_059 TLLIAMPQFFMEQYKYE----RYSPSSNSTLSISPCLLESSSQLPVSVMEKSKSKISNEC
130 140 150 160 170
170 180 190 200 210 220
pF1KE6 LNRTATNMMYLLLIGAQVLLGIGATPVQPLGVSYIDDHVRRKDSSLYIGILFTMLVFGPA
:...: ...: ..: ::: ::.::::..:.:: . . ....::: . :. ..::
NP_059 EVDTSSSMWIYVFLG-NLLRGIGETPIQPLGIAYLDDFASEDNAAFYIGCVQTVAIIGPI
180 190 200 210 220 230
230 240 250 260 270 280
pF1KE6 CGFILGSFCTKIYVDAVFIDTSNLDITPDDPRWIGAWWGGFLLCGALLFFSSLLMFGFPQ
::.:::.:.:.::: :.. ... ::: ::.:.:::: :.:. : . ..... .. .:.
NP_059 FGFLLGSLCAKLYVDIGFVNLDHITITPKDPQWVGAWWLGYLIAGIISLLAAVPFWYLPK
240 250 260 270 280 290
290 300 310 320 330 340
pF1KE6 SLP---PHSDPAMESEQAML---SEREYERPKPSNGVLRHPLEPDSSASCFQQLRVIPKV
::: . : ::.. . .. .:. :. : :. ... : .
NP_059 SLPRSQSREDSNSSSEKSKFIIDDHTDYQTPQGEN------------AKIMEMARDFLPS
300 310 320 330 340
350 360 370 380 390 400
pF1KE6 TKHLLSNPVFTCIILAACMEIAVVAGFAAFLGKYLEQQFNLTTSSANQLLGMTAIPCACL
:.:..:::. . .. ... . :.... ::.:::.. ..: :: ..:. :: . :
NP_059 LKNLFGNPVYFLYLCTSTVQFNSLFGMVTYKPKYIEQQYGQSSSRANFVIGLINIPAVAL
350 360 370 380 390 400
410 420 430 440 450 460
pF1KE6 GIFLGGLLVKKLSLSALGAIRMAMLVNLVSTACYVSFLFLGCDTGPVAGVTVPYGNSTAP
::: ::...::. .:. :: .. . .. . ..:.. :::... :::.:: : ..: :
NP_059 GIFSGGIVMKKFRISVCGAAKLYLGSSVFGYLLFLSLFALGCENSDVAGLTVSY-QGTKP
410 420 430 440 450 460
470 480 490 500 510
pF1KE6 GSALDP--YSPCNNNCECQTDSFTPVCGADGITYLSACFAGCNSTNLTG-------CACL
: . .: ::. :.:. .. :.:: .::::.:::.:::...: .: :.:.
NP_059 VSYHERALFSDCNSRCKCSETKWEPMCGENGITYVSACLAGCQTSNRSGKNIIFYNCTCV
470 480 490 500 510 520
520 530 540 550 560
pF1KE6 TTVPAE--NATVVPGKCPSP-GCQEAFLTFLCVMCICSLIGAMAQTPSVIILIRTVSPEL
. .. :.. . :.: . :: . :: :: . : : ... :. :.:.: ..:.:
NP_059 GIAASKSGNSSGIVGRCQKDNGCPQMFLYFLVISVITSYTLSLGGIPGYILLLRCIKPQL
530 540 550 560 570 580
570 580 590 600 610 620
pF1KE6 KSYALGVLFLLLRLLGFIPPPLIFGAGIDSTCLFWS-TFCGEQGACVLYDNVVYRYLYVS
::.:::. : .:.:. :: :. ::. ::..:: :. :: .:.: :::. :.:..:..
NP_059 KSFALGIYTLAIRVLAGIPAPVYFGVLIDTSCLKWGFKRCGSRGSCRLYDSNVFRHIYLG
590 600 610 620 630 640
630 640 650 660 670 680
pF1KE6 IAIALKSFAFILYTTTWQCLRKNY----KRYIKNHEGGLSTSTEYQDIETEKTCPESHSP
... : . ...: .. :.::: . .: ..: . .::..:
NP_059 LTVILGTVSILLSIAVLFILKKNYVSKHRSFITKRERTM-VSTRFQKENYTTSDHLLQPN
650 660 670 680 690 700
690
pF1KE6 SEDSFVRS
NP_059 YWPGKETQL
710
>>XP_005253451 (OMIM: 613389) PREDICTED: solute carrier (712 aa)
initn: 1452 init1: 393 opt: 1428 Z-score: 1567.5 bits: 300.5 E(85289): 1.4e-80
Smith-Waterman score: 1434; 34.6% identity (67.2% similar) in 676 aa overlap (30-670:33-689)
10 20 30 40 50
pF1KE6 MQGKKPGGSSGGGRSGELQGDEAQRNKKKKKKVSCFSNIKIFLVSECALMLAQGTVGAY
..: : ...:.:: . ...:.. . .:
XP_005 TSSKENIQLFCKTSVQPVGRPSFKTEYPSSEEKQPCCGELKVFLCALSFVYFAKALAEGY
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE6 LVSVLTTLERRFNLQSADVGVIASSFEIGNLALILFVSYFGARGHRPRLIGCGGIVMALG
: :..: .::::.. :. :::: .::::::: .: :::::::. :::..:: : ..:..:
XP_005 LKSTITQIERRFDIPSSLVGVIDGSFEIGNLLVITFVSYFGAKLHRPKIIGAGCVIMGVG
70 80 90 100 110 120
120 130 140 150 160
pF1KE6 ALLSALPEFLTHQYKYEAGEIRWGAEGRDV-----CAANGSGGD-----EGPDPDLI--C
.:: :.:.:. .::::: :.. . .. : ..:. : . :
XP_005 TLLIAMPQFFMEQYKYE----RYSPSSNSTLSISPCLLESSSQLPVSVMEKSKSKISNEC
130 140 150 160 170
170 180 190 200 210 220
pF1KE6 LNRTATNMMYLLLIGAQVLLGIGATPVQPLGVSYIDDHVRRKDSSLYIGILFTMLVFGPA
:...: ...: ..: ::: ::.::::..:.:: . . ....::: . :. ..::
XP_005 EVDTSSSMWIYVFLG-NLLRGIGETPIQPLGIAYLDDFASEDNAAFYIGCVQTVAIIGPI
180 190 200 210 220 230
230 240 250 260 270 280
pF1KE6 CGFILGSFCTKIYVDAVFIDTSNLDITPDDPRWIGAWWGGFLLCGALLFFSSLLMFGFPQ
::.:::.:.:.::: :.. ... ::: ::.:.:::: :.:. : . ..... .. .:.
XP_005 FGFLLGSLCAKLYVDIGFVNLDHITITPKDPQWVGAWWLGYLIAGIISLLAAVPFWYLPK
240 250 260 270 280 290
290 300 310 320 330 340
pF1KE6 SLP---PHSDPAMESEQAML---SEREYERPKPSNGVLRHPLEPDSSASCFQQLRVIPKV
::: . : ::.. . .. .:. :. : :. ... : .
XP_005 SLPRSQSREDSNSSSEKSKFIIDDHTDYQTPQGEN------------AKIMEMARDFLPS
300 310 320 330 340
350 360 370 380 390 400
pF1KE6 TKHLLSNPVFTCIILAACMEIAVVAGFAAFLGKYLEQQFNLTTSSANQLLGMTAIPCACL
:.:..:::. . .. ... . :.... ::.:::.. ..: :: ..:. :: . :
XP_005 LKNLFGNPVYFLYLCTSTVQFNSLFGMVTYKPKYIEQQYGQSSSRANFVIGLINIPAVAL
350 360 370 380 390 400
410 420 430 440 450 460
pF1KE6 GIFLGGLLVKKLSLSALGAIRMAMLVNLVSTACYVSFLFLGCDTGPVAGVTVPYGNSTAP
::: ::...::. .:. :: .. . .. . ..:.. :::... :::.:: : ..: :
XP_005 GIFSGGIVMKKFRISVCGAAKLYLGSSVFGYLLFLSLFALGCENSDVAGLTVSY-QGTKP
410 420 430 440 450 460
470 480 490 500 510
pF1KE6 GSALDP--YSPCNNNCECQTDSFTPVCGADGITYLSACFAGCNSTNLTG-------CACL
: . .: ::. :.:. .. :.:: .::::.:::.:::...: .: :.:.
XP_005 VSYHERALFSDCNSRCKCSETKWEPMCGENGITYVSACLAGCQTSNRSGKNIIFYNCTCV
470 480 490 500 510 520
520 530 540 550 560
pF1KE6 TTVPAE--NATVVPGKCPSP-GCQEAFLTFLCVMCICSLIGAMAQTPSVIILIRTVSPEL
. .. :.. . :.: . :: . :: :: . : : ... :. :.:.: ..:.:
XP_005 GIAASKSGNSSGIVGRCQKDNGCPQMFLYFLVISVITSYTLSLGGIPGYILLLRCIKPQL
530 540 550 560 570 580
570 580 590 600 610 620
pF1KE6 KSYALGVLFLLLRLLGFIPPPLIFGAGIDSTCLFWS-TFCGEQGACVLYDNVVYRYLYVS
::.:::. : .:.:. :: :. ::. ::..:: :. :: .:.: :::. :.:..:..
XP_005 KSFALGIYTLAIRVLAGIPAPVYFGVLIDTSCLKWGFKRCGSRGSCRLYDSNVFRHIYLG
590 600 610 620 630 640
630 640 650 660 670 680
pF1KE6 IAIALKSFAFILYTTTWQCLRKNY----KRYIKNHEGGLSTSTEYQDIETEKTCPESHSP
... : . ...: .. :.::: . .: ..: . .::..:
XP_005 LTVILGTVSILLSIAVLFILKKNYVSKHRSFITKRERTM-VSTRFQKENYTTSDHLLQPN
650 660 670 680 690 700
690
pF1KE6 SEDSFVRS
XP_005 YWPGKETQL
710
>>NP_062818 (OMIM: 237450,605495) solute carrier organic (702 aa)
initn: 1190 init1: 372 opt: 1395 Z-score: 1531.3 bits: 293.8 E(85289): 1.5e-78
Smith-Waterman score: 1395; 34.5% identity (69.0% similar) in 652 aa overlap (23-653:11-652)
10 20 30 40 50 60
pF1KE6 MQGKKPGGSSGGGRSGELQGDEAQRNKKKKKKVSCFSNIKIFLVSECALMLAQGTVGAYL
:. ...:::. ...:.::.. ..:.. : .
NP_062 MDQHQHLNKTAESASSEKKKTRRCNGFKMFLAALSFSYIAKALGGIIM
10 20 30 40
70 80 90 100 110 120
pF1KE6 VSVLTTLERRFNLQSADVGVIASSFEIGNLALILFVSYFGARGHRPRLIGCGGIVMALGA
.: .::::...:. .:.: .::::::: .:.::::::.. :::.::: : ..:. :.
NP_062 KISITQIERRFDISSSLAGLIDGSFEIGNLLVIVFVSYFGSKLHRPKLIGIGCLLMGTGS
50 60 70 80 90 100
130 140 150 160 170
pF1KE6 LLSALPEFLTHQYKY----EAGEIRWGAEGRDVCAANGSGGDEGPDPDLI---CLNRTAT
.:..::.:. :.: . . . .. . ..: : . . .: .:... :......
NP_062 ILTSLPHFFMGYYRYSKETHINPSENSTSSLSTCLINQTLSFNGTSPEIVEKDCVKESGS
110 120 130 140 150 160
180 190 200 210 220 230
pF1KE6 NMMYLLLIGAQVLLGIGATPVQPLGVSYIDDHVRRKDSSLYIGILFTMLVFGPACGFILG
.: ...: ..: ::: ::. :::.::::: ... ::::.: : .. ..::. :: ::
NP_062 HMWIYVFMG-NMLRGIGETPIVPLGISYIDDFAKEGHSSLYLGSLNAIGMIGPVIGFALG
170 180 190 200 210 220
240 250 260 270 280 290
pF1KE6 SFCTKIYVDAVFIDTSNLDITPDDPRWIGAWWGGFLLCGALLFFSSLLMFGFPQSLP--P
:. .:.::: ..: :.. ::: : ::.:::: :::. : . ..::. .: .:.. : :
NP_062 SLFAKMYVDIGYVDLSTIRITPKDSRWVGAWWLGFLVSGLFSIISSIPFFFLPKN-PNKP
230 240 250 260 270 280
300 310 320 330 340 350
pF1KE6 HSDPAMESEQAMLSEREYERPKPSNGVLRHPLEPDSSASCFQQLRVIPKVTKHLLSNPVF
... . .:. . .: . .: . . . .. ::.: : .:.::..
NP_062 QKERKISLSLHVLKTND-DRNQTANLTNQGKNVTKNVTGFFQSL-------KSILTNPLY
290 300 310 320 330
360 370 380 390 400 410
pF1KE6 TCIILAACMEIAVVAGFAAFLGKYLEQQFNLTTSSANQLLGMTAIPCACLGIFLGGLLVK
. ..: . .... : ... ::.:::.. ..: :: :::. .:: . :.::::...:
NP_062 VIFLLLTLLQVSSFIGSFTYVFKYMEQQYGQSASHANFLLGIITIPTVATGMFLGGFIIK
340 350 360 370 380 390
420 430 440 450 460 470
pF1KE6 KLSLSALGAIRMAMLVNLVSTACYVSFLFLGCDTGPVAGVTVPYGNSTAPGSALD-PYSP
:..:: .: ....:....: . .. : :.. :::.:. : .... .: .: : :
NP_062 KFKLSLVGIAKFSFLTSMISFLFQLLYFPLICESKSVAGLTLTYDGNNSVASHVDVPLSY
400 410 420 430 440 450
480 490 500 510 520
pF1KE6 CNNNCECQTDSFTPVCGADGITYLSACFAGCNSTN-------LTGCACL--TTVPAENAT
::..:.:. ... :::: .:::::: :.:::.:.. . .:.:. : . .: .
NP_062 CNSECNCDESQWEPVCGNNGITYLSPCLAGCKSSSGIKKHTVFYNCSCVEVTGLQNRNYS
460 470 480 490 500 510
530 540 550 560 570 580
pF1KE6 VVPGKCPSPG-CQEAFLTFLCVMCICSLIGAMAQTPSVIILIRTVSPELKSYALGVLFLL
. :.:: . : . :. .. .. : ::..: . : ... .. :.::::. :.: ..
NP_062 AHLGECPRDNTCTRKFFIYVAIQVINSLFSATGGTTFILLTVKIVQPELKALAMGFQSMV
520 530 540 550 560 570
590 600 610 620 630
pF1KE6 LRLLGFIPPPLIFGAGIDSTCLFWST-FCGEQGACVLYDNVVYRYLYVSIAIALKSFAFI
.: :: : :. ::: ::.::. ::: :: :::: .:..: . .:....:::. :..
NP_062 IRTLGGILAPIYFGALIDKTCMKWSTNSCGAQGACRIYNSVFFGRVYLGLSIALRFPALV
580 590 600 610 620 630
640 650 660 670 680 690
pF1KE6 LYTTTWQCLRKNYKRYIKNHEGGLSTSTEYQDIETEKTCPESHSPSEDSFVRS
:: . ..:...
NP_062 LYIVFIFAMKKKFQGKDTKASDNERKVMDEANLEFLNNGEHFVPSAGTDSKTCNLDMQDN
640 650 660 670 680 690
>>XP_011519005 (OMIM: 613389) PREDICTED: solute carrier (729 aa)
initn: 1346 init1: 393 opt: 1392 Z-score: 1527.8 bits: 293.2 E(85289): 2.3e-78
Smith-Waterman score: 1398; 34.3% identity (65.1% similar) in 688 aa overlap (30-682:33-696)
10 20 30 40 50
pF1KE6 MQGKKPGGSSGGGRSGELQGDEAQRNKKKKKKVSCFSNIKIFLVSECALMLAQGTVGAY
..: : ...:.:: . ...:.. . .:
XP_011 TSSKENIQLFCKTSVQPVGRPSFKTEYPSSEEKQPCCGELKVFLCALSFVYFAKALAEGY
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE6 LVSVLTTLERRFNLQSADVGVIASSFEIGNLALILFVSYFGARGHRPRLIGCGGIVMALG
: :..: .::::.. :. :::: .::::::: .: :::::::. :::..:: : ..:..:
XP_011 LKSTITQIERRFDIPSSLVGVIDGSFEIGNLLVITFVSYFGAKLHRPKIIGAGCVIMGVG
70 80 90 100 110 120
120 130 140 150 160
pF1KE6 ALLSALPEFLTHQYKYEAGEIRWGAEGRDV-----CAANGSGGD-----EGPDPDLI--C
.:: :.:.:. .::::: :.. . .. : ..:. : . :
XP_011 TLLIAMPQFFMEQYKYE----RYSPSSNSTLSISPCLLESSSQLPVSVMEKSKSKISNEC
130 140 150 160 170
170 180 190 200 210 220
pF1KE6 LNRTATNMMYLLLIGAQVLLGIGATPVQPLGVSYIDDHVRRKDSSLYIGILFTMLVFGPA
:...: ...: ..: ::: ::.::::..:.:: . . ....::: . :. ..::
XP_011 EVDTSSSMWIYVFLG-NLLRGIGETPIQPLGIAYLDDFASEDNAAFYIGCVQTVAIIGPI
180 190 200 210 220 230
230 240 250 260 270 280
pF1KE6 CGFILGSFCTKIYVDAVFIDTSNLDITPDDPRWIGAWWGGFLLCGALLFFSSLLMFGFPQ
::.:::.:.:.::: :.. ... ::: ::.:.:::: :.:. : . ..... .. .:.
XP_011 FGFLLGSLCAKLYVDIGFVNLDHITITPKDPQWVGAWWLGYLIAGIISLLAAVPFWYLPK
240 250 260 270 280 290
290 300 310 320 330 340
pF1KE6 SLP---PHSDPAMESEQAML---SEREYERPKPSNGVLRHPLEPDSSASCFQQLRVIPKV
::: . : ::.. . .. .:. :. : :. ... : .
XP_011 SLPRSQSREDSNSSSEKSKFIIDDHTDYQTPQGEN------------AKIMEMARDFLPS
300 310 320 330 340
350 360 370 380 390 400
pF1KE6 TKHLLSNPVFTCIILAACMEIAVVAGFAAFLGKYLEQQFNLTTSSANQLLGMTAIPCACL
:.:..:::. . .. ... . :.... ::.:::.. ..: :: ..:. :: . :
XP_011 LKNLFGNPVYFLYLCTSTVQFNSLFGMVTYKPKYIEQQYGQSSSRANFVIGLINIPAVAL
350 360 370 380 390 400
410 420 430 440 450 460
pF1KE6 GIFLGGLLVKKLSLSALGAIRMAMLVNLVSTACYVSFLFLGCDTGPVAGVTVPYGNSTAP
::: ::...::. .:. :: .. . .. . ..:.. :::... :::.:: : ..: :
XP_011 GIFSGGIVMKKFRISVCGAAKLYLGSSVFGYLLFLSLFALGCENSDVAGLTVSY-QGTKP
410 420 430 440 450 460
470 480 490 500 510
pF1KE6 GSALDP--YSPCNNNCECQTDSFTPVCGADGITYLSACFAGCNSTNLTG-------CACL
: . .: ::. :.:. .. :.:: .::::.:::.:::...: .: :.:.
XP_011 VSYHERALFSDCNSRCKCSETKWEPMCGENGITYVSACLAGCQTSNRSGKNIIFYNCTCV
470 480 490 500 510 520
520 530 540 550 560
pF1KE6 TTVPAE--NATVVPGKCPSP-GCQEAFLTFLCVMCICSLIGAMAQTPSVIILIRTVSPEL
. .. :.. . :.: . :: . :: :: . : : ... :. :.:.: ..:.:
XP_011 GIAASKSGNSSGIVGRCQKDNGCPQMFLYFLVISVITSYTLSLGGIPGYILLLRCIKPQL
530 540 550 560 570 580
570 580 590 600 610 620
pF1KE6 KSYALGVLFLLLRLLGFIPPPLIFGAGIDSTCLFWS-TFCGEQGACVLYDNVVYRYLYVS
::.:::. : .:.:: :: :. ::. ::..:: :. :: .:.: :::. :.:: :
XP_011 KSFALGIYTLAIRVLG-IPAPVYFGVLIDTSCLKWGFKRCGSRGSCRLYDSNVFRYQIKS
590 600 610 620 630 640
630 640 650 660 670 680
pF1KE6 IAIA----LKSFAFILYTTTWQCLRKNYKRYIKNHEGGLSTSTEYQDIETEKTCPESHSP
: . . .. :. ..: : ::. : . .: .. ... : : :
XP_011 IPASHCYSIPDLHNATDTNKFSCHFTACKTYIS----GTNCDTGHS-VNSPKHCSTFHFK
650 660 670 680 690
690
pF1KE6 SEDSFVRS
XP_011 EKLCFKTQKFYNQERKNNGVYKIPKGKLHYK
700 710 720
692 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Nov 8 15:35:55 2016 done: Tue Nov 8 15:35:57 2016
Total Scan time: 11.970 Total Display time: 0.190
Function used was FASTA [36.3.4 Apr, 2011]