Result of FASTA (omim) for
pFN21AE6696
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE6696, 400 aa
1>>>pF1KE6696 400 - 400 aa - 400 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.8578+/-0.000341; mu= 10.6468+/- 0.021
mean_var=148.6949+/-30.288, 0's: 0 Z-trim(118.8): 368 B-trim: 236 in 1/52
Lambda= 0.105178
statistics sampled from 31696 (32180) to 31696 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.724), E-opt: 0.2 (0.377), width: 16
Scan time: 8.120
The best scores are: opt bits E(85289)
XP_016879265 (OMIM: 604567) PREDICTED: double C2-l ( 400) 2699 421.2 2.2e-117
XP_011544277 (OMIM: 604567) PREDICTED: double C2-l ( 400) 2699 421.2 2.2e-117
XP_016879266 (OMIM: 604567) PREDICTED: double C2-l ( 400) 2699 421.2 2.2e-117
NP_001268997 (OMIM: 604567) double C2-like domain- ( 400) 2699 421.2 2.2e-117
NP_003577 (OMIM: 604567) double C2-like domain-con ( 400) 2699 421.2 2.2e-117
NP_001268992 (OMIM: 604567) double C2-like domain- ( 400) 2699 421.2 2.2e-117
NP_001268991 (OMIM: 604567) double C2-like domain- ( 400) 2699 421.2 2.2e-117
XP_016879267 (OMIM: 604567) PREDICTED: double C2-l ( 282) 1888 298.0 1.9e-80
XP_016874523 (OMIM: 612159) PREDICTED: rabphilin-3 ( 346) 1402 224.4 3.4e-58
NP_055769 (OMIM: 612159) rabphilin-3A isoform 2 [H ( 690) 1402 224.6 5.6e-58
XP_011536350 (OMIM: 612159) PREDICTED: rabphilin-3 ( 694) 1402 224.6 5.6e-58
NP_001137326 (OMIM: 612159) rabphilin-3A isoform 1 ( 694) 1402 224.6 5.6e-58
NP_003576 (OMIM: 604568) double C2-like domain-con ( 412) 803 133.5 8.9e-31
XP_011533665 (OMIM: 604568) PREDICTED: double C2-l ( 387) 793 132.0 2.4e-30
XP_016880716 (OMIM: 604568) PREDICTED: double C2-l ( 340) 750 125.4 2e-28
XP_016877187 (OMIM: 610950) PREDICTED: synaptotagm ( 339) 385 70.0 9.6e-12
XP_011535531 (OMIM: 610950) PREDICTED: synaptotagm ( 424) 385 70.1 1.1e-11
XP_016877185 (OMIM: 610950) PREDICTED: synaptotagm ( 462) 385 70.2 1.2e-11
XP_011535530 (OMIM: 610950) PREDICTED: synaptotagm ( 464) 385 70.2 1.2e-11
XP_011535529 (OMIM: 610950) PREDICTED: synaptotagm ( 505) 385 70.2 1.3e-11
XP_011535526 (OMIM: 610950) PREDICTED: synaptotagm ( 533) 385 70.2 1.3e-11
XP_011535527 (OMIM: 610950) PREDICTED: synaptotagm ( 533) 385 70.2 1.3e-11
XP_011535525 (OMIM: 610950) PREDICTED: synaptotagm ( 535) 385 70.2 1.3e-11
XP_016877184 (OMIM: 610950) PREDICTED: synaptotagm ( 645) 385 70.3 1.5e-11
XP_011535521 (OMIM: 610950) PREDICTED: synaptotagm ( 645) 385 70.3 1.5e-11
NP_114120 (OMIM: 610950) synaptotagmin-16 [Homo sa ( 645) 385 70.3 1.5e-11
XP_006720335 (OMIM: 610950) PREDICTED: synaptotagm ( 645) 385 70.3 1.5e-11
XP_016877183 (OMIM: 610950) PREDICTED: synaptotagm ( 645) 385 70.3 1.5e-11
XP_016877182 (OMIM: 610950) PREDICTED: synaptotagm ( 645) 385 70.3 1.5e-11
XP_006719639 (OMIM: 185605) PREDICTED: synaptotagm ( 419) 354 65.4 2.9e-10
XP_005269170 (OMIM: 185605) PREDICTED: synaptotagm ( 419) 354 65.4 2.9e-10
NP_001278830 (OMIM: 185605) synaptotagmin-1 isofor ( 419) 354 65.4 2.9e-10
NP_005630 (OMIM: 185605) synaptotagmin-1 isoform 1 ( 422) 354 65.4 2.9e-10
XP_011537012 (OMIM: 185605) PREDICTED: synaptotagm ( 422) 354 65.4 2.9e-10
XP_016875398 (OMIM: 185605) PREDICTED: synaptotagm ( 422) 354 65.4 2.9e-10
NP_001129277 (OMIM: 185605) synaptotagmin-1 isofor ( 422) 354 65.4 2.9e-10
NP_001129278 (OMIM: 185605) synaptotagmin-1 isofor ( 422) 354 65.4 2.9e-10
NP_796376 (OMIM: 600104,616040) synaptotagmin-2 [H ( 419) 350 64.8 4.4e-10
NP_001129976 (OMIM: 600104,616040) synaptotagmin-2 ( 419) 350 64.8 4.4e-10
XP_016855802 (OMIM: 600104,616040) PREDICTED: syna ( 419) 350 64.8 4.4e-10
XP_011507494 (OMIM: 600104,616040) PREDICTED: syna ( 422) 350 64.8 4.5e-10
XP_016855801 (OMIM: 600104,616040) PREDICTED: syna ( 422) 350 64.8 4.5e-10
XP_016855800 (OMIM: 600104,616040) PREDICTED: syna ( 422) 350 64.8 4.5e-10
XP_016855799 (OMIM: 600104,616040) PREDICTED: syna ( 476) 350 64.9 4.9e-10
XP_016855798 (OMIM: 600104,616040) PREDICTED: syna ( 479) 350 64.9 4.9e-10
NP_001284703 (OMIM: 600782) synaptotagmin-5 isofor ( 382) 340 63.2 1.2e-09
XP_006723404 (OMIM: 600782) PREDICTED: synaptotagm ( 383) 340 63.3 1.2e-09
XP_006723403 (OMIM: 600782) PREDICTED: synaptotagm ( 385) 340 63.3 1.2e-09
XP_016882664 (OMIM: 600782) PREDICTED: synaptotagm ( 386) 340 63.3 1.2e-09
XP_016882665 (OMIM: 600782) PREDICTED: synaptotagm ( 386) 340 63.3 1.2e-09
>>XP_016879265 (OMIM: 604567) PREDICTED: double C2-like (400 aa)
initn: 2699 init1: 2699 opt: 2699 Z-score: 2228.5 bits: 421.2 E(85289): 2.2e-117
Smith-Waterman score: 2699; 99.8% identity (100.0% similar) in 400 aa overlap (1-400:1-400)
10 20 30 40 50 60
pF1KE6 MRGRRGDRMTINIQEHMAINVCPGPIRPIRQISDYFPRGPGPEGGGGSGGEAPAHLVPLA
:::::::::::::::::::::::::::::::::::::::::::::::.::::::::::::
XP_016 MRGRRGDRMTINIQEHMAINVCPGPIRPIRQISDYFPRGPGPEGGGGGGGEAPAHLVPLA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 LAPPAALLGATTPEDGAEVDSYDSDDATALGTLEFDLLYDRASCTLHCSILRAKGLKPMD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LAPPAALLGATTPEDGAEVDSYDSDDATALGTLEFDLLYDRASCTLHCSILRAKGLKPMD
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 FNGLADPYVKLHLLPGACKANKLKTKTQRNTLNPVWNEDLTYSGITDDDITHKVLRIAVC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FNGLADPYVKLHLLPGACKANKLKTKTQRNTLNPVWNEDLTYSGITDDDITHKVLRIAVC
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE6 DEDKLSHNEFIGEIRVPLRRLKPSQKKHFNICLERQVPLASPSSMSAALRGISCYLKELE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DEDKLSHNEFIGEIRVPLRRLKPSQKKHFNICLERQVPLASPSSMSAALRGISCYLKELE
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE6 QAEQGQGLLEERGRILLSLSYSSRRRGLLVGILRCAHLAAMDVNGYSDPYVKTYLRPDVD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QAEQGQGLLEERGRILLSLSYSSRRRGLLVGILRCAHLAAMDVNGYSDPYVKTYLRPDVD
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE6 KKSKHKTCVKKKTLNPEFNEEFFYEIELSTLATKTLEVTVWDYDIGKSNDFIGGVSLGPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KKSKHKTCVKKKTLNPEFNEEFFYEIELSTLATKTLEVTVWDYDIGKSNDFIGGVSLGPG
310 320 330 340 350 360
370 380 390 400
pF1KE6 ARGEARKHWSDCLQQPDAALERWHTLTSELPPAAGALSSA
::::::::::::::::::::::::::::::::::::::::
XP_016 ARGEARKHWSDCLQQPDAALERWHTLTSELPPAAGALSSA
370 380 390 400
>>XP_011544277 (OMIM: 604567) PREDICTED: double C2-like (400 aa)
initn: 2699 init1: 2699 opt: 2699 Z-score: 2228.5 bits: 421.2 E(85289): 2.2e-117
Smith-Waterman score: 2699; 99.8% identity (100.0% similar) in 400 aa overlap (1-400:1-400)
10 20 30 40 50 60
pF1KE6 MRGRRGDRMTINIQEHMAINVCPGPIRPIRQISDYFPRGPGPEGGGGSGGEAPAHLVPLA
:::::::::::::::::::::::::::::::::::::::::::::::.::::::::::::
XP_011 MRGRRGDRMTINIQEHMAINVCPGPIRPIRQISDYFPRGPGPEGGGGGGGEAPAHLVPLA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 LAPPAALLGATTPEDGAEVDSYDSDDATALGTLEFDLLYDRASCTLHCSILRAKGLKPMD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LAPPAALLGATTPEDGAEVDSYDSDDATALGTLEFDLLYDRASCTLHCSILRAKGLKPMD
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 FNGLADPYVKLHLLPGACKANKLKTKTQRNTLNPVWNEDLTYSGITDDDITHKVLRIAVC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FNGLADPYVKLHLLPGACKANKLKTKTQRNTLNPVWNEDLTYSGITDDDITHKVLRIAVC
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE6 DEDKLSHNEFIGEIRVPLRRLKPSQKKHFNICLERQVPLASPSSMSAALRGISCYLKELE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DEDKLSHNEFIGEIRVPLRRLKPSQKKHFNICLERQVPLASPSSMSAALRGISCYLKELE
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE6 QAEQGQGLLEERGRILLSLSYSSRRRGLLVGILRCAHLAAMDVNGYSDPYVKTYLRPDVD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QAEQGQGLLEERGRILLSLSYSSRRRGLLVGILRCAHLAAMDVNGYSDPYVKTYLRPDVD
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE6 KKSKHKTCVKKKTLNPEFNEEFFYEIELSTLATKTLEVTVWDYDIGKSNDFIGGVSLGPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KKSKHKTCVKKKTLNPEFNEEFFYEIELSTLATKTLEVTVWDYDIGKSNDFIGGVSLGPG
310 320 330 340 350 360
370 380 390 400
pF1KE6 ARGEARKHWSDCLQQPDAALERWHTLTSELPPAAGALSSA
::::::::::::::::::::::::::::::::::::::::
XP_011 ARGEARKHWSDCLQQPDAALERWHTLTSELPPAAGALSSA
370 380 390 400
>>XP_016879266 (OMIM: 604567) PREDICTED: double C2-like (400 aa)
initn: 2699 init1: 2699 opt: 2699 Z-score: 2228.5 bits: 421.2 E(85289): 2.2e-117
Smith-Waterman score: 2699; 99.8% identity (100.0% similar) in 400 aa overlap (1-400:1-400)
10 20 30 40 50 60
pF1KE6 MRGRRGDRMTINIQEHMAINVCPGPIRPIRQISDYFPRGPGPEGGGGSGGEAPAHLVPLA
:::::::::::::::::::::::::::::::::::::::::::::::.::::::::::::
XP_016 MRGRRGDRMTINIQEHMAINVCPGPIRPIRQISDYFPRGPGPEGGGGGGGEAPAHLVPLA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 LAPPAALLGATTPEDGAEVDSYDSDDATALGTLEFDLLYDRASCTLHCSILRAKGLKPMD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LAPPAALLGATTPEDGAEVDSYDSDDATALGTLEFDLLYDRASCTLHCSILRAKGLKPMD
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 FNGLADPYVKLHLLPGACKANKLKTKTQRNTLNPVWNEDLTYSGITDDDITHKVLRIAVC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FNGLADPYVKLHLLPGACKANKLKTKTQRNTLNPVWNEDLTYSGITDDDITHKVLRIAVC
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE6 DEDKLSHNEFIGEIRVPLRRLKPSQKKHFNICLERQVPLASPSSMSAALRGISCYLKELE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DEDKLSHNEFIGEIRVPLRRLKPSQKKHFNICLERQVPLASPSSMSAALRGISCYLKELE
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE6 QAEQGQGLLEERGRILLSLSYSSRRRGLLVGILRCAHLAAMDVNGYSDPYVKTYLRPDVD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QAEQGQGLLEERGRILLSLSYSSRRRGLLVGILRCAHLAAMDVNGYSDPYVKTYLRPDVD
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE6 KKSKHKTCVKKKTLNPEFNEEFFYEIELSTLATKTLEVTVWDYDIGKSNDFIGGVSLGPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KKSKHKTCVKKKTLNPEFNEEFFYEIELSTLATKTLEVTVWDYDIGKSNDFIGGVSLGPG
310 320 330 340 350 360
370 380 390 400
pF1KE6 ARGEARKHWSDCLQQPDAALERWHTLTSELPPAAGALSSA
::::::::::::::::::::::::::::::::::::::::
XP_016 ARGEARKHWSDCLQQPDAALERWHTLTSELPPAAGALSSA
370 380 390 400
>>NP_001268997 (OMIM: 604567) double C2-like domain-cont (400 aa)
initn: 2699 init1: 2699 opt: 2699 Z-score: 2228.5 bits: 421.2 E(85289): 2.2e-117
Smith-Waterman score: 2699; 99.8% identity (100.0% similar) in 400 aa overlap (1-400:1-400)
10 20 30 40 50 60
pF1KE6 MRGRRGDRMTINIQEHMAINVCPGPIRPIRQISDYFPRGPGPEGGGGSGGEAPAHLVPLA
:::::::::::::::::::::::::::::::::::::::::::::::.::::::::::::
NP_001 MRGRRGDRMTINIQEHMAINVCPGPIRPIRQISDYFPRGPGPEGGGGGGGEAPAHLVPLA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 LAPPAALLGATTPEDGAEVDSYDSDDATALGTLEFDLLYDRASCTLHCSILRAKGLKPMD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LAPPAALLGATTPEDGAEVDSYDSDDATALGTLEFDLLYDRASCTLHCSILRAKGLKPMD
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 FNGLADPYVKLHLLPGACKANKLKTKTQRNTLNPVWNEDLTYSGITDDDITHKVLRIAVC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FNGLADPYVKLHLLPGACKANKLKTKTQRNTLNPVWNEDLTYSGITDDDITHKVLRIAVC
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE6 DEDKLSHNEFIGEIRVPLRRLKPSQKKHFNICLERQVPLASPSSMSAALRGISCYLKELE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DEDKLSHNEFIGEIRVPLRRLKPSQKKHFNICLERQVPLASPSSMSAALRGISCYLKELE
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE6 QAEQGQGLLEERGRILLSLSYSSRRRGLLVGILRCAHLAAMDVNGYSDPYVKTYLRPDVD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QAEQGQGLLEERGRILLSLSYSSRRRGLLVGILRCAHLAAMDVNGYSDPYVKTYLRPDVD
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE6 KKSKHKTCVKKKTLNPEFNEEFFYEIELSTLATKTLEVTVWDYDIGKSNDFIGGVSLGPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KKSKHKTCVKKKTLNPEFNEEFFYEIELSTLATKTLEVTVWDYDIGKSNDFIGGVSLGPG
310 320 330 340 350 360
370 380 390 400
pF1KE6 ARGEARKHWSDCLQQPDAALERWHTLTSELPPAAGALSSA
::::::::::::::::::::::::::::::::::::::::
NP_001 ARGEARKHWSDCLQQPDAALERWHTLTSELPPAAGALSSA
370 380 390 400
>>NP_003577 (OMIM: 604567) double C2-like domain-contain (400 aa)
initn: 2699 init1: 2699 opt: 2699 Z-score: 2228.5 bits: 421.2 E(85289): 2.2e-117
Smith-Waterman score: 2699; 99.8% identity (100.0% similar) in 400 aa overlap (1-400:1-400)
10 20 30 40 50 60
pF1KE6 MRGRRGDRMTINIQEHMAINVCPGPIRPIRQISDYFPRGPGPEGGGGSGGEAPAHLVPLA
:::::::::::::::::::::::::::::::::::::::::::::::.::::::::::::
NP_003 MRGRRGDRMTINIQEHMAINVCPGPIRPIRQISDYFPRGPGPEGGGGGGGEAPAHLVPLA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 LAPPAALLGATTPEDGAEVDSYDSDDATALGTLEFDLLYDRASCTLHCSILRAKGLKPMD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 LAPPAALLGATTPEDGAEVDSYDSDDATALGTLEFDLLYDRASCTLHCSILRAKGLKPMD
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 FNGLADPYVKLHLLPGACKANKLKTKTQRNTLNPVWNEDLTYSGITDDDITHKVLRIAVC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 FNGLADPYVKLHLLPGACKANKLKTKTQRNTLNPVWNEDLTYSGITDDDITHKVLRIAVC
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE6 DEDKLSHNEFIGEIRVPLRRLKPSQKKHFNICLERQVPLASPSSMSAALRGISCYLKELE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 DEDKLSHNEFIGEIRVPLRRLKPSQKKHFNICLERQVPLASPSSMSAALRGISCYLKELE
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE6 QAEQGQGLLEERGRILLSLSYSSRRRGLLVGILRCAHLAAMDVNGYSDPYVKTYLRPDVD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 QAEQGQGLLEERGRILLSLSYSSRRRGLLVGILRCAHLAAMDVNGYSDPYVKTYLRPDVD
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE6 KKSKHKTCVKKKTLNPEFNEEFFYEIELSTLATKTLEVTVWDYDIGKSNDFIGGVSLGPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 KKSKHKTCVKKKTLNPEFNEEFFYEIELSTLATKTLEVTVWDYDIGKSNDFIGGVSLGPG
310 320 330 340 350 360
370 380 390 400
pF1KE6 ARGEARKHWSDCLQQPDAALERWHTLTSELPPAAGALSSA
::::::::::::::::::::::::::::::::::::::::
NP_003 ARGEARKHWSDCLQQPDAALERWHTLTSELPPAAGALSSA
370 380 390 400
>>NP_001268992 (OMIM: 604567) double C2-like domain-cont (400 aa)
initn: 2699 init1: 2699 opt: 2699 Z-score: 2228.5 bits: 421.2 E(85289): 2.2e-117
Smith-Waterman score: 2699; 99.8% identity (100.0% similar) in 400 aa overlap (1-400:1-400)
10 20 30 40 50 60
pF1KE6 MRGRRGDRMTINIQEHMAINVCPGPIRPIRQISDYFPRGPGPEGGGGSGGEAPAHLVPLA
:::::::::::::::::::::::::::::::::::::::::::::::.::::::::::::
NP_001 MRGRRGDRMTINIQEHMAINVCPGPIRPIRQISDYFPRGPGPEGGGGGGGEAPAHLVPLA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 LAPPAALLGATTPEDGAEVDSYDSDDATALGTLEFDLLYDRASCTLHCSILRAKGLKPMD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LAPPAALLGATTPEDGAEVDSYDSDDATALGTLEFDLLYDRASCTLHCSILRAKGLKPMD
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 FNGLADPYVKLHLLPGACKANKLKTKTQRNTLNPVWNEDLTYSGITDDDITHKVLRIAVC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FNGLADPYVKLHLLPGACKANKLKTKTQRNTLNPVWNEDLTYSGITDDDITHKVLRIAVC
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE6 DEDKLSHNEFIGEIRVPLRRLKPSQKKHFNICLERQVPLASPSSMSAALRGISCYLKELE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DEDKLSHNEFIGEIRVPLRRLKPSQKKHFNICLERQVPLASPSSMSAALRGISCYLKELE
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE6 QAEQGQGLLEERGRILLSLSYSSRRRGLLVGILRCAHLAAMDVNGYSDPYVKTYLRPDVD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QAEQGQGLLEERGRILLSLSYSSRRRGLLVGILRCAHLAAMDVNGYSDPYVKTYLRPDVD
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE6 KKSKHKTCVKKKTLNPEFNEEFFYEIELSTLATKTLEVTVWDYDIGKSNDFIGGVSLGPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KKSKHKTCVKKKTLNPEFNEEFFYEIELSTLATKTLEVTVWDYDIGKSNDFIGGVSLGPG
310 320 330 340 350 360
370 380 390 400
pF1KE6 ARGEARKHWSDCLQQPDAALERWHTLTSELPPAAGALSSA
::::::::::::::::::::::::::::::::::::::::
NP_001 ARGEARKHWSDCLQQPDAALERWHTLTSELPPAAGALSSA
370 380 390 400
>>NP_001268991 (OMIM: 604567) double C2-like domain-cont (400 aa)
initn: 2699 init1: 2699 opt: 2699 Z-score: 2228.5 bits: 421.2 E(85289): 2.2e-117
Smith-Waterman score: 2699; 99.8% identity (100.0% similar) in 400 aa overlap (1-400:1-400)
10 20 30 40 50 60
pF1KE6 MRGRRGDRMTINIQEHMAINVCPGPIRPIRQISDYFPRGPGPEGGGGSGGEAPAHLVPLA
:::::::::::::::::::::::::::::::::::::::::::::::.::::::::::::
NP_001 MRGRRGDRMTINIQEHMAINVCPGPIRPIRQISDYFPRGPGPEGGGGGGGEAPAHLVPLA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 LAPPAALLGATTPEDGAEVDSYDSDDATALGTLEFDLLYDRASCTLHCSILRAKGLKPMD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LAPPAALLGATTPEDGAEVDSYDSDDATALGTLEFDLLYDRASCTLHCSILRAKGLKPMD
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 FNGLADPYVKLHLLPGACKANKLKTKTQRNTLNPVWNEDLTYSGITDDDITHKVLRIAVC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FNGLADPYVKLHLLPGACKANKLKTKTQRNTLNPVWNEDLTYSGITDDDITHKVLRIAVC
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE6 DEDKLSHNEFIGEIRVPLRRLKPSQKKHFNICLERQVPLASPSSMSAALRGISCYLKELE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DEDKLSHNEFIGEIRVPLRRLKPSQKKHFNICLERQVPLASPSSMSAALRGISCYLKELE
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE6 QAEQGQGLLEERGRILLSLSYSSRRRGLLVGILRCAHLAAMDVNGYSDPYVKTYLRPDVD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QAEQGQGLLEERGRILLSLSYSSRRRGLLVGILRCAHLAAMDVNGYSDPYVKTYLRPDVD
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE6 KKSKHKTCVKKKTLNPEFNEEFFYEIELSTLATKTLEVTVWDYDIGKSNDFIGGVSLGPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KKSKHKTCVKKKTLNPEFNEEFFYEIELSTLATKTLEVTVWDYDIGKSNDFIGGVSLGPG
310 320 330 340 350 360
370 380 390 400
pF1KE6 ARGEARKHWSDCLQQPDAALERWHTLTSELPPAAGALSSA
::::::::::::::::::::::::::::::::::::::::
NP_001 ARGEARKHWSDCLQQPDAALERWHTLTSELPPAAGALSSA
370 380 390 400
>>XP_016879267 (OMIM: 604567) PREDICTED: double C2-like (282 aa)
initn: 1888 init1: 1888 opt: 1888 Z-score: 1565.4 bits: 298.0 E(85289): 1.9e-80
Smith-Waterman score: 1888; 100.0% identity (100.0% similar) in 282 aa overlap (119-400:1-282)
90 100 110 120 130 140
pF1KE6 ALGTLEFDLLYDRASCTLHCSILRAKGLKPMDFNGLADPYVKLHLLPGACKANKLKTKTQ
::::::::::::::::::::::::::::::
XP_016 MDFNGLADPYVKLHLLPGACKANKLKTKTQ
10 20 30
150 160 170 180 190 200
pF1KE6 RNTLNPVWNEDLTYSGITDDDITHKVLRIAVCDEDKLSHNEFIGEIRVPLRRLKPSQKKH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RNTLNPVWNEDLTYSGITDDDITHKVLRIAVCDEDKLSHNEFIGEIRVPLRRLKPSQKKH
40 50 60 70 80 90
210 220 230 240 250 260
pF1KE6 FNICLERQVPLASPSSMSAALRGISCYLKELEQAEQGQGLLEERGRILLSLSYSSRRRGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FNICLERQVPLASPSSMSAALRGISCYLKELEQAEQGQGLLEERGRILLSLSYSSRRRGL
100 110 120 130 140 150
270 280 290 300 310 320
pF1KE6 LVGILRCAHLAAMDVNGYSDPYVKTYLRPDVDKKSKHKTCVKKKTLNPEFNEEFFYEIEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LVGILRCAHLAAMDVNGYSDPYVKTYLRPDVDKKSKHKTCVKKKTLNPEFNEEFFYEIEL
160 170 180 190 200 210
330 340 350 360 370 380
pF1KE6 STLATKTLEVTVWDYDIGKSNDFIGGVSLGPGARGEARKHWSDCLQQPDAALERWHTLTS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 STLATKTLEVTVWDYDIGKSNDFIGGVSLGPGARGEARKHWSDCLQQPDAALERWHTLTS
220 230 240 250 260 270
390 400
pF1KE6 ELPPAAGALSSA
::::::::::::
XP_016 ELPPAAGALSSA
280
>>XP_016874523 (OMIM: 612159) PREDICTED: rabphilin-3A is (346 aa)
initn: 1362 init1: 708 opt: 1402 Z-score: 1165.7 bits: 224.4 E(85289): 3.4e-58
Smith-Waterman score: 1402; 62.3% identity (83.7% similar) in 332 aa overlap (60-389:13-340)
30 40 50 60 70 80
pF1KE6 RQISDYFPRGPGPEGGGGSGGEAPAHLVPLALAP-PAALLGATTPEDGAE-VDSYDSDDA
: :: ::: ::. : ..:::::.:
XP_016 MSHPSGPYSQASAAAPQPAAARQPPPPEEEEEEANSYDSDEA
10 20 30 40
90 100 110 120 130 140
pF1KE6 TALGTLEFDLLYDRASCTLHCSILRAKGLKPMDFNGLADPYVKLHLLPGACKANKLKTKT
:.::.:::.::::. . .:.:.:..:::::::: :::::::::::::::: :.:::.:::
XP_016 TTLGALEFSLLYDQDNSSLQCTIIKAKGLKPMDSNGLADPYVKLHLLPGASKSNKLRTKT
50 60 70 80 90 100
150 160 170 180 190 200
pF1KE6 QRNTLNPVWNEDLTYSGITDDDITHKVLRIAVCDEDKLSHNEFIGEIRVPLRRLKPSQKK
::: ::.::: :.: ::::.:. .:.:::.::::::..::::::: : :..:::.:.:
XP_016 LRNTRNPIWNETLVYHGITDEDMQRKTLRISVCDEDKFGHNEFIGETRFSLKKLKPNQRK
110 120 130 140 150 160
210 220 230 240 250 260
pF1KE6 HFNICLERQVPLASPSSMSAALRGISCYLKELEQAEQGQGLLEERGRILLSLSYSSRRRG
.::::::: .:. .. ..: ::.. : : ::.:. : .::::.::.:: ::... :
XP_016 NFNICLERVIPMKRAGTTGSA-RGMALY--EEEQVER-VGDIEERGKILVSLMYSTQQGG
170 180 190 200 210
270 280 290 300 310 320
pF1KE6 LLVGILRCAHLAAMDVNGYSDPYVKTYLRPDVDKKSKHKTCVKKKTLNPEFNEEFFYEIE
:.:::.::.::::::.::::::.:: .:.::. ::.:::: .:::::::::::::::.:.
XP_016 LIVGIIRCVHLAAMDANGYSDPFVKLWLKPDMGKKAKHKTQIKKKTLNPEFNEEFFYDIK
220 230 240 250 260 270
330 340 350 360 370 380
pF1KE6 LSTLATKTLEVTVWDYDIGKSNDFIGGVSLGPGARGEARKHWSDCLQQPDAALERWHTLT
: :: :.:...:::::::::::.::: .:: .:.:: ::: .::.. : .:::: :
XP_016 HSDLAKKSLDISVWDYDIGKSNDYIGGCQLGISAKGERLKHWYECLKNKDKKIERWHQLQ
280 290 300 310 320 330
390 400
pF1KE6 SELPPAAGALSSA
.:
XP_016 NENHVSSD
340
>>NP_055769 (OMIM: 612159) rabphilin-3A isoform 2 [Homo (690 aa)
initn: 1399 init1: 708 opt: 1402 Z-score: 1161.8 bits: 224.6 E(85289): 5.6e-58
Smith-Waterman score: 1409; 56.6% identity (75.6% similar) in 389 aa overlap (23-389:300-684)
10 20 30 40
pF1KE6 MRGRRGDRMTINIQEHMAINVCPGPI-RPIRQISDYFPRGPG---P---EGG
::: : : . : :: : :
NP_055 QASRPAPGSVQSPAPPQPGQPGTPGGSRPGPGPAGRFPDQKPEVAPSDPGTTAPPREERT
270 280 290 300 310 320
50 60 70 80 90
pF1KE6 GGSGG--------------EAPAHLVPLALAPPAALLGATTPEDGAE-VDSYDSDDATAL
:: :: .: . : ::: ::. : ..:::::.::.:
NP_055 GGVGGYPAVGAREDRMSHPSGPYSQASAAAPQPAAARQPPPPEEEEEEANSYDSDEATTL
330 340 350 360 370 380
100 110 120 130 140 150
pF1KE6 GTLEFDLLYDRASCTLHCSILRAKGLKPMDFNGLADPYVKLHLLPGACKANKLKTKTQRN
:.:::.::::. . .:.:.:..:::::::: :::::::::::::::: :.:::.::: ::
NP_055 GALEFSLLYDQDNSSLQCTIIKAKGLKPMDSNGLADPYVKLHLLPGASKSNKLRTKTLRN
390 400 410 420 430 440
160 170 180 190 200 210
pF1KE6 TLNPVWNEDLTYSGITDDDITHKVLRIAVCDEDKLSHNEFIGEIRVPLRRLKPSQKKHFN
: ::.::: :.: ::::.:. .:.:::.::::::..::::::: : :..:::.:.:.::
NP_055 TRNPIWNETLVYHGITDEDMQRKTLRISVCDEDKFGHNEFIGETRFSLKKLKPNQRKNFN
450 460 470 480 490 500
220 230 240 250 260 270
pF1KE6 ICLERQVPLASPSSMSAALRGISCYLKELEQAEQGQGLLEERGRILLSLSYSSRRRGLLV
::::: .:. .. ..: ::.. : : ::.:. : .::::.::.:: ::... ::.:
NP_055 ICLERVIPMKRAGTTGSA-RGMALY--EEEQVER-VGDIEERGKILVSLMYSTQQGGLIV
510 520 530 540 550 560
280 290 300 310 320 330
pF1KE6 GILRCAHLAAMDVNGYSDPYVKTYLRPDVDKKSKHKTCVKKKTLNPEFNEEFFYEIELST
::.::.::::::.::::::.:: .:.::. ::.:::: .:::::::::::::::.:. :
NP_055 GIIRCVHLAAMDANGYSDPFVKLWLKPDMGKKAKHKTQIKKKTLNPEFNEEFFYDIKHSD
570 580 590 600 610 620
340 350 360 370 380 390
pF1KE6 LATKTLEVTVWDYDIGKSNDFIGGVSLGPGARGEARKHWSDCLQQPDAALERWHTLTSEL
:: :.:...:::::::::::.::: .:: .:.:: ::: .::.. : .:::: : .:
NP_055 LAKKSLDISVWDYDIGKSNDYIGGCQLGISAKGERLKHWYECLKNKDKKIERWHQLQNEN
630 640 650 660 670 680
400
pF1KE6 PPAAGALSSA
NP_055 HVSSD
690
400 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Nov 8 15:29:46 2016 done: Tue Nov 8 15:29:48 2016
Total Scan time: 8.120 Total Display time: 0.040
Function used was FASTA [36.3.4 Apr, 2011]