Result of FASTA (omim) for
pFN21AE6693
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE6693, 318 aa
1>>>pF1KE6693 318 - 318 aa - 318 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.6325+/-0.000503; mu= 8.8615+/- 0.031
mean_var=215.1582+/-47.297, 0's: 0 Z-trim(115.6): 427 B-trim: 93 in 1/49
Lambda= 0.087437
statistics sampled from 25540 (26134) to 25540 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.685), E-opt: 0.2 (0.306), width: 16
Scan time: 5.360
The best scores are: opt bits E(85289)
NP_569059 (OMIM: 300891) ankyrin repeat and SOCS b ( 318) 2111 279.5 6.2e-75
NP_001035535 (OMIM: 605758) ankyrin repeat and SOC ( 335) 582 86.7 7.4e-17
NP_001317125 (OMIM: 605758) ankyrin repeat and SOC ( 234) 305 51.5 2e-06
NP_665862 (OMIM: 605760) ankyrin repeat and SOCS b ( 445) 266 47.0 8.7e-05
NP_001188894 (OMIM: 605760) ankyrin repeat and SOC ( 445) 266 47.0 8.7e-05
NP_001183959 (OMIM: 610500) ankyrin repeat and KH ( 581) 267 47.3 9.3e-05
NP_057199 (OMIM: 605760) ankyrin repeat and SOCS b ( 518) 266 47.1 9.5e-05
NP_060448 (OMIM: 610500) ankyrin repeat and KH dom ( 616) 267 47.3 9.6e-05
NP_078944 (OMIM: 610500) ankyrin repeat and KH dom ( 627) 267 47.3 9.7e-05
NP_060217 (OMIM: 610500) ankyrin repeat and KH dom (2542) 267 48.2 0.00022
XP_016863506 (OMIM: 615929) PREDICTED: ankyrin rep (1116) 259 46.7 0.00027
XP_016863505 (OMIM: 615929) PREDICTED: ankyrin rep (1229) 259 46.7 0.00029
XP_016863504 (OMIM: 615929) PREDICTED: ankyrin rep (1367) 259 46.8 0.00031
XP_016863503 (OMIM: 615929) PREDICTED: ankyrin rep (1479) 259 46.8 0.00032
XP_005265730 (OMIM: 615929) PREDICTED: ankyrin rep (1480) 259 46.8 0.00032
XP_005265729 (OMIM: 615929) PREDICTED: ankyrin rep (1543) 259 46.9 0.00033
XP_016863502 (OMIM: 615929) PREDICTED: ankyrin rep (2238) 259 47.1 0.00041
XP_016863501 (OMIM: 615929) PREDICTED: ankyrin rep (2239) 259 47.1 0.00041
XP_005265728 (OMIM: 615929) PREDICTED: ankyrin rep (2351) 259 47.1 0.00042
NP_942592 (OMIM: 615929) ankyrin repeat domain-con (2352) 259 47.1 0.00042
XP_016863500 (OMIM: 615929) PREDICTED: ankyrin rep (2489) 259 47.1 0.00043
NP_001273700 (OMIM: 615929) ankyrin repeat domain- (2490) 259 47.1 0.00043
NP_056389 (OMIM: 615929) ankyrin repeat domain-con (2602) 259 47.2 0.00045
NP_115593 (OMIM: 615929) ankyrin repeat domain-con (2603) 259 47.2 0.00045
NP_076992 (OMIM: 300890) ankyrin repeat and SOCS b ( 262) 218 40.6 0.0042
NP_001162003 (OMIM: 300890) ankyrin repeat and SOC ( 262) 218 40.6 0.0042
NP_001026909 (OMIM: 300890) ankyrin repeat and SOC ( 294) 218 40.7 0.0045
XP_005274503 (OMIM: 300890) PREDICTED: ankyrin rep ( 294) 218 40.7 0.0045
XP_016884774 (OMIM: 300890) PREDICTED: ankyrin rep ( 345) 218 40.8 0.005
XP_016884775 (OMIM: 300890) PREDICTED: ankyrin rep ( 345) 218 40.8 0.005
XP_016884772 (OMIM: 300890) PREDICTED: ankyrin rep ( 377) 218 40.8 0.0052
XP_011538517 (OMIM: 607128) PREDICTED: tankyrase-2 ( 695) 222 41.7 0.0053
NP_065210 (OMIM: 182900,612641) ankyrin-1 isoform (1719) 228 43.0 0.0053
XP_011542807 (OMIM: 182900,612641) PREDICTED: anky (1751) 228 43.0 0.0053
XP_011542806 (OMIM: 182900,612641) PREDICTED: anky (1752) 228 43.0 0.0053
XP_016868818 (OMIM: 182900,612641) PREDICTED: anky (1759) 228 43.0 0.0053
XP_011542805 (OMIM: 182900,612641) PREDICTED: anky (1791) 228 43.0 0.0054
XP_016868817 (OMIM: 182900,612641) PREDICTED: anky (1792) 228 43.0 0.0054
XP_016868816 (OMIM: 182900,612641) PREDICTED: anky (1807) 228 43.0 0.0054
NP_065208 (OMIM: 182900,612641) ankyrin-1 isoform (1856) 228 43.1 0.0055
NP_000028 (OMIM: 182900,612641) ankyrin-1 isoform (1880) 228 43.1 0.0055
NP_065209 (OMIM: 182900,612641) ankyrin-1 isoform (1881) 228 43.1 0.0055
XP_011542804 (OMIM: 182900,612641) PREDICTED: anky (1889) 228 43.1 0.0056
XP_016868815 (OMIM: 182900,612641) PREDICTED: anky (1892) 228 43.1 0.0056
NP_001135918 (OMIM: 182900,612641) ankyrin-1 isofo (1897) 228 43.1 0.0056
XP_016868814 (OMIM: 182900,612641) PREDICTED: anky (1908) 228 43.1 0.0056
XP_011542803 (OMIM: 182900,612641) PREDICTED: anky (1913) 228 43.1 0.0056
XP_011542802 (OMIM: 182900,612641) PREDICTED: anky (1914) 228 43.1 0.0056
XP_005273533 (OMIM: 182900,612641) PREDICTED: anky (1921) 228 43.1 0.0056
XP_016868813 (OMIM: 182900,612641) PREDICTED: anky (1922) 228 43.1 0.0056
>>NP_569059 (OMIM: 300891) ankyrin repeat and SOCS box p (318 aa)
initn: 2111 init1: 2111 opt: 2111 Z-score: 1466.3 bits: 279.5 E(85289): 6.2e-75
Smith-Waterman score: 2111; 100.0% identity (100.0% similar) in 318 aa overlap (1-318:1-318)
10 20 30 40 50 60
pF1KE6 MRIVLQLAKMNLMDITKIFSLLQPDKEEEDTDTEEKQALNQAVYDNDSYTLDQLLRQERY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_569 MRIVLQLAKMNLMDITKIFSLLQPDKEEEDTDTEEKQALNQAVYDNDSYTLDQLLRQERY
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 KRFINSRSGWGVPGTPLRLAASYGHLSCLQVLLAHGADVDSLDVKAQTPLFTAVSHGHLD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_569 KRFINSRSGWGVPGTPLRLAASYGHLSCLQVLLAHGADVDSLDVKAQTPLFTAVSHGHLD
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 CVRVLLEAGASPGGSIYNNCSPVLTAARDGAVAILQELLDHGAEANVKAKLPVWASNIAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_569 CVRVLLEAGASPGGSIYNNCSPVLTAARDGAVAILQELLDHGAEANVKAKLPVWASNIAS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE6 CSGPLYLAAVYGHLDCFRLLLLHGADPDYNCTDQGLLARVPRPRTLLEICLHHNCEPEYI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_569 CSGPLYLAAVYGHLDCFRLLLLHGADPDYNCTDQGLLARVPRPRTLLEICLHHNCEPEYI
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE6 QLLIDFGANIYLPSLSLDLTSQDDKGIALLLQARATPRSLLSQVRLVVRRALCQAGQPQA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_569 QLLIDFGANIYLPSLSLDLTSQDDKGIALLLQARATPRSLLSQVRLVVRRALCQAGQPQA
250 260 270 280 290 300
310
pF1KE6 INQLDIPPMLISYLKHQL
::::::::::::::::::
NP_569 INQLDIPPMLISYLKHQL
310
>>NP_001035535 (OMIM: 605758) ankyrin repeat and SOCS bo (335 aa)
initn: 684 init1: 303 opt: 582 Z-score: 423.7 bits: 86.7 E(85289): 7.4e-17
Smith-Waterman score: 647; 39.8% identity (68.4% similar) in 304 aa overlap (35-317:37-335)
10 20 30 40 50 60
pF1KE6 LQLAKMNLMDITKIFSLLQPDKEEEDTDTEEKQALNQAVYDNDSYTLDQLLRQERYKRFI
: :..:.: .: :: .::..: :. :
NP_001 PDGRAGPGSAGRNLKEWLREQFCDHPLEHCEDTRLHDAAYVGDLQTLRSLLQEESYRSRI
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 NSRSGW--G-VPGTPLRLAASYGHLSCLQVLLAHGADVDSLDVKAQTPLFTAVSHGHLDC
: .: : : .: ::::.::. :: ::.. :. .::.:: .:::.:: :..:: .:::.
NP_001 NEKSVWCCGWLPCTPLRIAATAGHGSCVDFLIRKGAEVDLVDVKGQTALYVAVVNGHLES
70 80 90 100 110 120
130 140 150 160 170
pF1KE6 VRVLLEAGASPGGSIYNNCSPVLTAARDGAVAILQELLDHGAEANVKAKL-----PVWAS
...::::::.:.:: .. .:: :.: : . ::. :. .::...:. .: : ..
NP_001 TQILLEAGADPNGSRHHRSTPVYHASRVGRADILKALIRYGADVDVNHHLTPDVQPRFSR
130 140 150 160 170 180
180 190 200 210 220
pF1KE6 NIAS---CSGPLYLAAVYGHLDCFRLLLLHGADPDYNCTD----QGLLARVPRPRTLLEI
..: : :::..:.: .:.::::::: ::.::.::. ::. : ...
NP_001 RLTSLVVC--PLYISAAYHNLQCFRLLLLAGANPDFNCNGPVNTQGFYR--GSPGCVMDA
190 200 210 220 230 240
230 240 250 260 270 280
pF1KE6 CLHHNCEPEYIQLLIDFGANIYLPSL-SLDLTSQ-----DDKGIALLLQARATPRSLLSQ
:.:.:: ...::..::::. : . :: :. : ... .. .::..::.::
NP_001 VLRHGCEAAFVSLLVEFGANLNLVKWESLGPESRGRRKVDPEALQVFKEARSVPRTLLCL
250 260 270 280 290 300
290 300 310
pF1KE6 VRLVVRRALCQAGQPQAINQLDIPPMLISYLKHQL
:..::::: . . . : .: .: . ..: :.
NP_001 CRVAVRRALGKH-RLHLIPSLPLPDPIKKFLLHE
310 320 330
>>NP_001317125 (OMIM: 605758) ankyrin repeat and SOCS bo (234 aa)
initn: 324 init1: 146 opt: 305 Z-score: 236.4 bits: 51.5 E(85289): 2e-06
Smith-Waterman score: 305; 33.7% identity (64.5% similar) in 169 aa overlap (159-317:71-234)
130 140 150 160 170 180
pF1KE6 GASPGGSIYNNCSPVLTAARDGAVAILQELLDHGAEANVKAKLPVWASNIASCSGPLYLA
..: .:. .. .... : :::..
NP_001 LHDAAYVGDLQTLRSLLQEESYRRYGADVDVNHHLTPDVQPRFSRRLTSLVVC--PLYIS
50 60 70 80 90
190 200 210 220 230 240
pF1KE6 AVYGHLDCFRLLLLHGADPDYNCTD----QGLLARVPRPRTLLEICLHHNCEPEYIQLLI
:.: .:.::::::: ::.::.::. ::. : ... :.:.:: ...::.
NP_001 AAYHNLQCFRLLLLAGANPDFNCNGPVNTQGFYR--GSPGCVMDAVLRHGCEAAFVSLLV
100 110 120 130 140 150
250 260 270 280 290
pF1KE6 DFGANIYLPSL-SLDLTSQ-----DDKGIALLLQARATPRSLLSQVRLVVRRALCQAGQP
.::::. : . :: :. : ... .. .::..::.:: :..::::: . .
NP_001 EFGANLNLVKWESLGPESRGRRKVDPEALQVFKEARSVPRTLLCLCRVAVRRALGKH-RL
160 170 180 190 200 210
300 310
pF1KE6 QAINQLDIPPMLISYLKHQL
. : .: .: . ..: :.
NP_001 HLIPSLPLPDPIKKFLLHE
220 230
>>NP_665862 (OMIM: 605760) ankyrin repeat and SOCS box p (445 aa)
initn: 404 init1: 178 opt: 266 Z-score: 207.0 bits: 47.0 E(85289): 8.7e-05
Smith-Waterman score: 277; 30.8% identity (60.6% similar) in 221 aa overlap (38-250:76-271)
10 20 30 40 50 60
pF1KE6 AKMNLMDITKIFSLLQPDKEEEDTDTEEKQALNQAVYDNDSYTLDQLLRQERYKRFINSR
.:.:: ..... . :::. :. .
NP_665 AVENGQIDVLRLLLQHGANVNGSHSMCGWNSLHQASFQENAEIIKLLLRKGANKE---CQ
50 60 70 80 90 100
70 80 90 100 110 120
pF1KE6 SGWGVPGTPLRLAASYGHLSCLQVLLAHGADVDSLDVKAQTPLFTAVSHGHLDCVRVLLE
. .:. ::: .::.::.: :..:.. ::.:. . :::: :...:: ::..::
NP_665 DDFGI--TPLFVAAQYGKLESLSILISSGANVNCQALDKATPLFIAAQEGHTKCVELLLS
110 120 130 140 150 160
130 140 150 160 170 180
pF1KE6 AGASPGGSIYNNCS----PVLTAARDGAVAILQELLDHGAEANVKAKLPVWASNIASCSG
.::.: ..: : . :. .::. : . ::. :. .: ... . :
NP_665 SGADP--DLYCNEDSWQLPIHAAAQMGHTKILDLLIPLTNRAC--------DTGLNKVS-
170 180 190 200
190 200 210 220 230
pF1KE6 PLYLAAVYGHLDCFRLLLLHGADPDYN-CTDQGLLARVPRPRTLLEICL--HHNCEPE-Y
:.: :. :: ::...:: .: .:: . : :. . : .:. ...::
NP_665 PVYSAVFGGHEDCLEILLRNGYSPDAQACLVFGFSS----P-----VCMAFQKDCEFFGI
210 220 230 240 250 260
240 250 260 270 280 290
pF1KE6 IQLLIDFGANIYLPSLSLDLTSQDDKGIALLLQARATPRSLLSQVRLVVRRALCQAGQPQ
...:. .::.:
NP_665 VNILLKYGAQINELHLAYCLKYEKFSIFRYFLRKGCSLGPWNHIYEFVNHAIKAQAKYKE
270 280 290 300 310 320
>>NP_001188894 (OMIM: 605760) ankyrin repeat and SOCS bo (445 aa)
initn: 404 init1: 178 opt: 266 Z-score: 207.0 bits: 47.0 E(85289): 8.7e-05
Smith-Waterman score: 277; 30.8% identity (60.6% similar) in 221 aa overlap (38-250:76-271)
10 20 30 40 50 60
pF1KE6 AKMNLMDITKIFSLLQPDKEEEDTDTEEKQALNQAVYDNDSYTLDQLLRQERYKRFINSR
.:.:: ..... . :::. :. .
NP_001 AVENGQIDVLRLLLQHGANVNGSHSMCGWNSLHQASFQENAEIIKLLLRKGANKE---CQ
50 60 70 80 90 100
70 80 90 100 110 120
pF1KE6 SGWGVPGTPLRLAASYGHLSCLQVLLAHGADVDSLDVKAQTPLFTAVSHGHLDCVRVLLE
. .:. ::: .::.::.: :..:.. ::.:. . :::: :...:: ::..::
NP_001 DDFGI--TPLFVAAQYGKLESLSILISSGANVNCQALDKATPLFIAAQEGHTKCVELLLS
110 120 130 140 150 160
130 140 150 160 170 180
pF1KE6 AGASPGGSIYNNCS----PVLTAARDGAVAILQELLDHGAEANVKAKLPVWASNIASCSG
.::.: ..: : . :. .::. : . ::. :. .: ... . :
NP_001 SGADP--DLYCNEDSWQLPIHAAAQMGHTKILDLLIPLTNRAC--------DTGLNKVS-
170 180 190 200
190 200 210 220 230
pF1KE6 PLYLAAVYGHLDCFRLLLLHGADPDYN-CTDQGLLARVPRPRTLLEICL--HHNCEPE-Y
:.: :. :: ::...:: .: .:: . : :. . : .:. ...::
NP_001 PVYSAVFGGHEDCLEILLRNGYSPDAQACLVFGFSS----P-----VCMAFQKDCEFFGI
210 220 230 240 250 260
240 250 260 270 280 290
pF1KE6 IQLLIDFGANIYLPSLSLDLTSQDDKGIALLLQARATPRSLLSQVRLVVRRALCQAGQPQ
...:. .::.:
NP_001 VNILLKYGAQINELHLAYCLKYEKFSIFRYFLRKGCSLGPWNHIYEFVNHAIKAQAKYKE
270 280 290 300 310 320
>>NP_001183959 (OMIM: 610500) ankyrin repeat and KH doma (581 aa)
initn: 460 init1: 206 opt: 267 Z-score: 206.4 bits: 47.3 E(85289): 9.3e-05
Smith-Waterman score: 309; 33.1% identity (58.4% similar) in 245 aa overlap (14-258:217-439)
10 20 30 40
pF1KE6 MRIVLQLAKMNLMDITKIFSLLQPDKEEEDTDTEEKQALNQAV
:.. . .::. . .. ::: ..: .
NP_001 AAALTRMKAENSHNAGQVDTRSLAEACSDGDVNAVRKLLDEGRSVNE-HTEEGESLLCLA
190 200 210 220 230 240
50 60 70 80 90 100
pF1KE6 YDNDSYTLDQLLRQERYKRFINSRSGWGVPGTPLRLAASYGHLSCLQVLLAHGADVDSLD
. : : :.: . . ...:.. : ::: :.: :.:. ...:: : :::.: .
NP_001 CSAGYYELAQVLLAMHAN--VEDRGNKG-DITPLMAASSGGYLDIVKLLLLHDADVNSQS
250 260 270 280 290 300
110 120 130 140 150 160
pF1KE6 VKAQTPLFTAVSHGHLDCVRVLLEAGASPGGSIYNNCSPVLTAARDGAVAILQELLDHGA
. ..: : : . : .: :.:::. ::. :. .:.. :: : : . . ::::::
NP_001 ATGNTALTYACAGGFVDIVKVLLNEGANIEDHNENGHTPLMEAASAGHVEVARVLLDHGA
310 320 330 340 350 360
170 180 190 200 210 220
pF1KE6 EANVKAKLPVWASNIASCSGPLYLAAVYGHLDCFRLLLLHGADPDYNCTDQGLLARVPRP
:.. :: . :. : :: :::: :.:: ::: ... ::. :
NP_001 GINTH-------SNEFKESA-LTLACYKGHLDMVRFLLEAGADQEHK-TDEMHTA-----
370 380 390 400
230 240 250 260 270 280
pF1KE6 RTLLEICLHHNCEPEYIQLLIDFGANIYLPSLSLDLTSQDDKGIALLLQARATPRSLLSQ
:.: :. . : .::.: ::.. .:. :..
NP_001 --LMEACMDGHVE--VARLLLDSGAQVNMPADSFESPLTLAACGGHVELAALLIERGANL
410 420 430 440 450 460
290 300 310
pF1KE6 VRLVVRRALCQAGQPQAINQLDIPPMLISYLKHQL
NP_001 EEVNDEGYTPLMEAAREGHEEMVALLLAQGANINAQTEETQETALTLACCGGFSEVADFL
470 480 490 500 510 520
>>NP_057199 (OMIM: 605760) ankyrin repeat and SOCS box p (518 aa)
initn: 404 init1: 178 opt: 266 Z-score: 206.3 bits: 47.1 E(85289): 9.5e-05
Smith-Waterman score: 277; 30.8% identity (60.6% similar) in 221 aa overlap (38-250:149-344)
10 20 30 40 50 60
pF1KE6 AKMNLMDITKIFSLLQPDKEEEDTDTEEKQALNQAVYDNDSYTLDQLLRQERYKRFINSR
.:.:: ..... . :::. :. .
NP_057 AVENGQIDVLRLLLQHGANVNGSHSMCGWNSLHQASFQENAEIIKLLLRKGANKE---CQ
120 130 140 150 160 170
70 80 90 100 110 120
pF1KE6 SGWGVPGTPLRLAASYGHLSCLQVLLAHGADVDSLDVKAQTPLFTAVSHGHLDCVRVLLE
. .:. ::: .::.::.: :..:.. ::.:. . :::: :...:: ::..::
NP_057 DDFGI--TPLFVAAQYGKLESLSILISSGANVNCQALDKATPLFIAAQEGHTKCVELLLS
180 190 200 210 220 230
130 140 150 160 170 180
pF1KE6 AGASPGGSIYNNCS----PVLTAARDGAVAILQELLDHGAEANVKAKLPVWASNIASCSG
.::.: ..: : . :. .::. : . ::. :. .: ... . :
NP_057 SGADP--DLYCNEDSWQLPIHAAAQMGHTKILDLLIPLTNRAC--------DTGLNKVS-
240 250 260 270 280
190 200 210 220 230
pF1KE6 PLYLAAVYGHLDCFRLLLLHGADPDYN-CTDQGLLARVPRPRTLLEICL--HHNCEPE-Y
:.: :. :: ::...:: .: .:: . : :. . : .:. ...::
NP_057 PVYSAVFGGHEDCLEILLRNGYSPDAQACLVFGFSS----P-----VCMAFQKDCEFFGI
290 300 310 320 330
240 250 260 270 280 290
pF1KE6 IQLLIDFGANIYLPSLSLDLTSQDDKGIALLLQARATPRSLLSQVRLVVRRALCQAGQPQ
...:. .::.:
NP_057 VNILLKYGAQINELHLAYCLKYEKFSIFRYFLRKGCSLGPWNHIYEFVNHAIKAQAKYKE
340 350 360 370 380 390
>>NP_060448 (OMIM: 610500) ankyrin repeat and KH domain- (616 aa)
initn: 521 init1: 206 opt: 267 Z-score: 206.2 bits: 47.3 E(85289): 9.6e-05
Smith-Waterman score: 309; 33.1% identity (58.4% similar) in 245 aa overlap (14-258:206-428)
10 20 30 40
pF1KE6 MRIVLQLAKMNLMDITKIFSLLQPDKEEEDTDTEEKQALNQAV
:.. . .::. . .. ::: ..: .
NP_060 AAALTRMKAENSHNAGQVDTRSLAEACSDGDVNAVRKLLDEGRSVNE-HTEEGESLLCLA
180 190 200 210 220 230
50 60 70 80 90 100
pF1KE6 YDNDSYTLDQLLRQERYKRFINSRSGWGVPGTPLRLAASYGHLSCLQVLLAHGADVDSLD
. : : :.: . . ...:.. : ::: :.: :.:. ...:: : :::.: .
NP_060 CSAGYYELAQVLLAMHAN--VEDRGNKG-DITPLMAASSGGYLDIVKLLLLHDADVNSQS
240 250 260 270 280 290
110 120 130 140 150 160
pF1KE6 VKAQTPLFTAVSHGHLDCVRVLLEAGASPGGSIYNNCSPVLTAARDGAVAILQELLDHGA
. ..: : : . : .: :.:::. ::. :. .:.. :: : : . . ::::::
NP_060 ATGNTALTYACAGGFVDIVKVLLNEGANIEDHNENGHTPLMEAASAGHVEVARVLLDHGA
300 310 320 330 340 350
170 180 190 200 210 220
pF1KE6 EANVKAKLPVWASNIASCSGPLYLAAVYGHLDCFRLLLLHGADPDYNCTDQGLLARVPRP
:.. :: . :. : :: :::: :.:: ::: ... ::. :
NP_060 GINTH-------SNEFKESA-LTLACYKGHLDMVRFLLEAGADQEHK-TDEMHTA-----
360 370 380 390
230 240 250 260 270 280
pF1KE6 RTLLEICLHHNCEPEYIQLLIDFGANIYLPSLSLDLTSQDDKGIALLLQARATPRSLLSQ
:.: :. . : .::.: ::.. .:. :..
NP_060 --LMEACMDGHVE--VARLLLDSGAQVNMPADSFESPLTLAACGGHVELAALLIERGANL
400 410 420 430 440 450
290 300 310
pF1KE6 VRLVVRRALCQAGQPQAINQLDIPPMLISYLKHQL
NP_060 EEVNDEGYTPLMEAAREGHEEMVALLLAQGANINAQTEETQETALTLACCGGFSEVADFL
460 470 480 490 500 510
>>NP_078944 (OMIM: 610500) ankyrin repeat and KH domain- (627 aa)
initn: 521 init1: 206 opt: 267 Z-score: 206.1 bits: 47.3 E(85289): 9.7e-05
Smith-Waterman score: 309; 33.1% identity (58.4% similar) in 245 aa overlap (14-258:217-439)
10 20 30 40
pF1KE6 MRIVLQLAKMNLMDITKIFSLLQPDKEEEDTDTEEKQALNQAV
:.. . .::. . .. ::: ..: .
NP_078 AAALTRMKAENSHNAGQVDTRSLAEACSDGDVNAVRKLLDEGRSVNE-HTEEGESLLCLA
190 200 210 220 230 240
50 60 70 80 90 100
pF1KE6 YDNDSYTLDQLLRQERYKRFINSRSGWGVPGTPLRLAASYGHLSCLQVLLAHGADVDSLD
. : : :.: . . ...:.. : ::: :.: :.:. ...:: : :::.: .
NP_078 CSAGYYELAQVLLAMHAN--VEDRGNKG-DITPLMAASSGGYLDIVKLLLLHDADVNSQS
250 260 270 280 290 300
110 120 130 140 150 160
pF1KE6 VKAQTPLFTAVSHGHLDCVRVLLEAGASPGGSIYNNCSPVLTAARDGAVAILQELLDHGA
. ..: : : . : .: :.:::. ::. :. .:.. :: : : . . ::::::
NP_078 ATGNTALTYACAGGFVDIVKVLLNEGANIEDHNENGHTPLMEAASAGHVEVARVLLDHGA
310 320 330 340 350 360
170 180 190 200 210 220
pF1KE6 EANVKAKLPVWASNIASCSGPLYLAAVYGHLDCFRLLLLHGADPDYNCTDQGLLARVPRP
:.. :: . :. : :: :::: :.:: ::: ... ::. :
NP_078 GINTH-------SNEFKESA-LTLACYKGHLDMVRFLLEAGADQEHK-TDEMHTA-----
370 380 390 400
230 240 250 260 270 280
pF1KE6 RTLLEICLHHNCEPEYIQLLIDFGANIYLPSLSLDLTSQDDKGIALLLQARATPRSLLSQ
:.: :. . : .::.: ::.. .:. :..
NP_078 --LMEACMDGHVE--VARLLLDSGAQVNMPADSFESPLTLAACGGHVELAALLIERGANL
410 420 430 440 450 460
290 300 310
pF1KE6 VRLVVRRALCQAGQPQAINQLDIPPMLISYLKHQL
NP_078 EEVNDEGYTPLMEAAREGHEEMVALLLAQGANINAQTEETQETALTLACCGGFSEVADFL
470 480 490 500 510 520
>>NP_060217 (OMIM: 610500) ankyrin repeat and KH domain- (2542 aa)
initn: 617 init1: 206 opt: 267 Z-score: 199.8 bits: 48.2 E(85289): 0.00022
Smith-Waterman score: 309; 33.1% identity (58.4% similar) in 245 aa overlap (14-258:217-439)
10 20 30 40
pF1KE6 MRIVLQLAKMNLMDITKIFSLLQPDKEEEDTDTEEKQALNQAV
:.. . .::. . .. ::: ..: .
NP_060 AAALTRMKAENSHNAGQVDTRSLAEACSDGDVNAVRKLLDEGRSVNE-HTEEGESLLCLA
190 200 210 220 230 240
50 60 70 80 90 100
pF1KE6 YDNDSYTLDQLLRQERYKRFINSRSGWGVPGTPLRLAASYGHLSCLQVLLAHGADVDSLD
. : : :.: . . ...:.. : ::: :.: :.:. ...:: : :::.: .
NP_060 CSAGYYELAQVLLAMHAN--VEDRGNKG-DITPLMAASSGGYLDIVKLLLLHDADVNSQS
250 260 270 280 290 300
110 120 130 140 150 160
pF1KE6 VKAQTPLFTAVSHGHLDCVRVLLEAGASPGGSIYNNCSPVLTAARDGAVAILQELLDHGA
. ..: : : . : .: :.:::. ::. :. .:.. :: : : . . ::::::
NP_060 ATGNTALTYACAGGFVDIVKVLLNEGANIEDHNENGHTPLMEAASAGHVEVARVLLDHGA
310 320 330 340 350 360
170 180 190 200 210 220
pF1KE6 EANVKAKLPVWASNIASCSGPLYLAAVYGHLDCFRLLLLHGADPDYNCTDQGLLARVPRP
:.. :: . :. : :: :::: :.:: ::: ... ::. :
NP_060 GINTH-------SNEFKESA-LTLACYKGHLDMVRFLLEAGADQEHK-TDEMHTA-----
370 380 390 400
230 240 250 260 270 280
pF1KE6 RTLLEICLHHNCEPEYIQLLIDFGANIYLPSLSLDLTSQDDKGIALLLQARATPRSLLSQ
:.: :. . : .::.: ::.. .:. :..
NP_060 --LMEACMDGHVE--VARLLLDSGAQVNMPADSFESPLTLAACGGHVELAALLIERGANL
410 420 430 440 450 460
290 300 310
pF1KE6 VRLVVRRALCQAGQPQAINQLDIPPMLISYLKHQL
NP_060 EEVNDEGYTPLMEAAREGHEEMVALLLAQGANINAQTEETQETALTLACCGGFSEVADFL
470 480 490 500 510 520
318 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Nov 8 15:27:58 2016 done: Tue Nov 8 15:27:59 2016
Total Scan time: 5.360 Total Display time: 0.010
Function used was FASTA [36.3.4 Apr, 2011]