Result of FASTA (omim) for
pFN21AE6671
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE6671, 296 aa
1>>>pF1KE6671 296 - 296 aa - 296 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.7646+/-0.000396; mu= 13.3465+/- 0.024
mean_var=87.2822+/-17.453, 0's: 0 Z-trim(113.9): 150 B-trim: 33 in 1/57
Lambda= 0.137281
statistics sampled from 23354 (23519) to 23354 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.661), E-opt: 0.2 (0.276), width: 16
Scan time: 5.410
The best scores are: opt bits E(85289)
NP_001181928 (OMIM: 600764) major histocompatibili ( 296) 2049 415.8 5.1e-116
XP_011507765 (OMIM: 600764) PREDICTED: major histo ( 254) 1295 266.4 4.1e-71
NP_001522 (OMIM: 600764) major histocompatibility ( 341) 1295 266.5 5.2e-71
NP_001181964 (OMIM: 600764) major histocompatibili ( 214) 761 160.6 2.5e-39
NP_001181929 (OMIM: 600764) major histocompatibili ( 249) 759 160.2 3.6e-39
XP_006711349 (OMIM: 600764) PREDICTED: major histo ( 312) 755 159.5 7.5e-39
NP_002107 (OMIM: 142800,608579) HLA class I histoc ( 365) 454 100.0 7.5e-21
XP_016866304 (OMIM: 143110) PREDICTED: HLA class I ( 228) 450 99.0 9e-21
XP_016866303 (OMIM: 143110) PREDICTED: HLA class I ( 324) 450 99.1 1.2e-20
NP_061823 (OMIM: 143110) HLA class I histocompatib ( 346) 450 99.1 1.2e-20
XP_016885777 (OMIM: 142800,608579) PREDICTED: HLA ( 362) 450 99.2 1.3e-20
XP_016866302 (OMIM: 143110) PREDICTED: HLA class I ( 388) 450 99.2 1.4e-20
XP_005275388 (OMIM: 142800,608579) PREDICTED: HLA ( 391) 450 99.2 1.4e-20
XP_016866301 (OMIM: 143110) PREDICTED: HLA class I ( 420) 450 99.2 1.5e-20
XP_016866299 (OMIM: 143110) PREDICTED: HLA class I ( 435) 450 99.2 1.5e-20
NP_001091949 (OMIM: 143110) HLA class I histocompa ( 442) 450 99.2 1.5e-20
XP_011512866 (OMIM: 143110) PREDICTED: HLA class I ( 343) 440 97.2 4.9e-20
XP_016866300 (OMIM: 143110) PREDICTED: HLA class I ( 431) 440 97.2 5.9e-20
NP_002118 (OMIM: 142871,600807) HLA class I histoc ( 338) 436 96.4 8.4e-20
XP_016866305 (OMIM: 142871,600807) PREDICTED: HLA ( 343) 436 96.4 8.5e-20
NP_001229687 (OMIM: 142800,608579) HLA class I his ( 365) 432 95.6 1.5e-19
NP_005505 (OMIM: 106300,142830,608579) major histo ( 362) 426 94.4 3.5e-19
NP_001229971 (OMIM: 142840,177900,609423) HLA clas ( 366) 416 92.4 1.4e-18
NP_002108 (OMIM: 142840,177900,609423) HLA class I ( 366) 416 92.4 1.4e-18
NP_005507 (OMIM: 143010) HLA class I histocompatib ( 358) 408 90.8 4.1e-18
XP_016866298 (OMIM: 143010) PREDICTED: HLA class I ( 359) 408 90.8 4.1e-18
XP_016866296 (OMIM: 143010) PREDICTED: HLA class I ( 399) 408 90.9 4.5e-18
XP_016866297 (OMIM: 143010) PREDICTED: HLA class I ( 399) 408 90.9 4.5e-18
NP_001276090 (OMIM: 602436) MHC class I polypeptid ( 340) 394 88.0 2.7e-17
NP_620576 (OMIM: 104300,176100,176200,235200,61263 ( 260) 382 85.6 1.1e-16
NP_620578 (OMIM: 104300,176100,176200,235200,61263 ( 325) 382 85.7 1.3e-16
XP_011512859 (OMIM: 106300,142830,608579) PREDICTE ( 323) 377 84.7 2.7e-16
NP_001176 (OMIM: 194460) zinc-alpha-2-glycoprotein ( 298) 370 83.3 6.5e-16
NP_001297142 (OMIM: 600764) major histocompatibili ( 178) 338 76.8 3.5e-14
XP_005258714 (OMIM: 601437) PREDICTED: IgG recepto ( 225) 317 72.7 7.6e-13
NP_004098 (OMIM: 601437) IgG receptor FcRn large s ( 365) 317 72.8 1.1e-12
NP_001129491 (OMIM: 601437) IgG receptor FcRn larg ( 365) 317 72.8 1.1e-12
XP_016866306 (OMIM: 142871,600807) PREDICTED: HLA ( 246) 312 71.7 1.6e-12
XP_016866307 (OMIM: 142871,600807) PREDICTED: HLA ( 246) 312 71.7 1.6e-12
NP_620579 (OMIM: 104300,176100,176200,235200,61263 ( 168) 305 70.2 3.1e-12
NP_000238 (OMIM: 600169) MHC class I polypeptide-r ( 383) 309 71.2 3.5e-12
NP_001276083 (OMIM: 600169) MHC class I polypeptid ( 194) 300 69.3 6.9e-12
NP_001276082 (OMIM: 600169) MHC class I polypeptid ( 235) 301 69.5 7e-12
NP_001276081 (OMIM: 600169) MHC class I polypeptid ( 235) 301 69.5 7e-12
NP_001170990 (OMIM: 600169) MHC class I polypeptid ( 332) 301 69.6 9.2e-12
NP_001276089 (OMIM: 602436) MHC class I polypeptid ( 351) 299 69.2 1.3e-11
NP_005922 (OMIM: 602436) MHC class I polypeptide-r ( 383) 299 69.3 1.4e-11
NP_620577 (OMIM: 104300,176100,176200,235200,61263 ( 246) 280 65.4 1.3e-10
XP_011524929 (OMIM: 601437) PREDICTED: IgG recepto ( 273) 275 64.4 2.8e-10
NP_001307581 (OMIM: 188370) T-cell surface glycopr ( 316) 275 64.5 3.2e-10
>>NP_001181928 (OMIM: 600764) major histocompatibility c (296 aa)
initn: 2049 init1: 2049 opt: 2049 Z-score: 2203.9 bits: 415.8 E(85289): 5.1e-116
Smith-Waterman score: 2049; 100.0% identity (100.0% similar) in 296 aa overlap (1-296:1-296)
10 20 30 40 50 60
pF1KE6 MGELMAFLLPLIIVLMVKHSDSRTHSLRYFRLGVSDPIHGVPEFISVGYVDSHPITTYDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MGELMAFLLPLIIVLMVKHSDSRTHSLRYFRLGVSDPIHGVPEFISVGYVDSHPITTYDS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 VTRQKEPRAPWMAENLAPDHWERYTQLLRGWQQMFKVELKRLQRHYNHSDNVAHTIKQAW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VTRQKEPRAPWMAENLAPDHWERYTQLLRGWQQMFKVELKRLQRHYNHSDNVAHTIKQAW
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 EANQHELLYQKNWLEEECIAWLKRFLEYGKDTLQRTEPPLVRVNRKETFPGVTALFCKAH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EANQHELLYQKNWLEEECIAWLKRFLEYGKDTLQRTEPPLVRVNRKETFPGVTALFCKAH
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE6 GFYPPEIYMTWMKNGEEIVQEIDYGDILPSGDGTYQAWASIELDPQSSNLYSCHVEHCGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GFYPPEIYMTWMKNGEEIVQEIDYGDILPSGDGTYQAWASIELDPQSSNLYSCHVEHCGV
190 200 210 220 230 240
250 260 270 280 290
pF1KE6 HMVLQVPQESETIPLVMKAVSGSIVLVIVLAGVGVLVWRRRPREQNGAIYLPTPDR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HMVLQVPQESETIPLVMKAVSGSIVLVIVLAGVGVLVWRRRPREQNGAIYLPTPDR
250 260 270 280 290
>>XP_011507765 (OMIM: 600764) PREDICTED: major histocomp (254 aa)
initn: 1439 init1: 1295 opt: 1295 Z-score: 1397.7 bits: 266.4 E(85289): 4.1e-71
Smith-Waterman score: 1361; 73.7% identity (79.1% similar) in 297 aa overlap (1-296:1-254)
10 20 30 40 50
pF1KE6 MGELMAFLLPLIIVLMVKHSDSRTHSLRYFRLGVSDPIHGVPE-FISVGYVDSHPITTYD
:::::::::::::::::::::::.:. . . .: : :.. .: :.. . ..
XP_011 MGELMAFLLPLIIVLMVKHSDSRSHTYQRM-IGCELLEDGSTTGFLQYAY-DGQDFLIFN
10 20 30 40 50
60 70 80 90 100 110
pF1KE6 SVTRQKEPRAPWMAENLAPDHWERYTQLLRGWQQMFKVELKRLQRHYNHSDNVAHTIKQA
. : . :.: ::::::::::
XP_011 KDTLS------WLA-----------------------------------VDNVAHTIKQA
60 70
120 130 140 150 160 170
pF1KE6 WEANQHELLYQKNWLEEECIAWLKRFLEYGKDTLQRTEPPLVRVNRKETFPGVTALFCKA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 WEANQHELLYQKNWLEEECIAWLKRFLEYGKDTLQRTEPPLVRVNRKETFPGVTALFCKA
80 90 100 110 120 130
180 190 200 210 220 230
pF1KE6 HGFYPPEIYMTWMKNGEEIVQEIDYGDILPSGDGTYQAWASIELDPQSSNLYSCHVEHCG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 HGFYPPEIYMTWMKNGEEIVQEIDYGDILPSGDGTYQAWASIELDPQSSNLYSCHVEHCG
140 150 160 170 180 190
240 250 260 270 280 290
pF1KE6 VHMVLQVPQESETIPLVMKAVSGSIVLVIVLAGVGVLVWRRRPREQNGAIYLPTPDR
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VHMVLQVPQESETIPLVMKAVSGSIVLVIVLAGVGVLVWRRRPREQNGAIYLPTPDR
200 210 220 230 240 250
>>NP_001522 (OMIM: 600764) major histocompatibility comp (341 aa)
initn: 2035 init1: 1295 opt: 1295 Z-score: 1395.9 bits: 266.5 E(85289): 5.2e-71
Smith-Waterman score: 1868; 86.3% identity (86.3% similar) in 328 aa overlap (14-296:14-341)
10 20 30 40 50 60
pF1KE6 MGELMAFLLPLIIVLMVKHSDSRTHSLRYFRLGVSDPIHGVPEFISVGYVDSHPITTYDS
:::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MGELMAFLLPLIIVLMVKHSDSRTHSLRYFRLGVSDPIHGVPEFISVGYVDSHPITTYDS
10 20 30 40 50 60
70 80 90 100
pF1KE6 VTRQKEPRAPWMAENLAPDHWERYTQLLRGWQQMFKVELKRLQRHYNHS-----------
:::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VTRQKEPRAPWMAENLAPDHWERYTQLLRGWQQMFKVELKRLQRHYNHSGSHTYQRMIGC
70 80 90 100 110 120
110 120 130
pF1KE6 ----------------------------------DNVAHTIKQAWEANQHELLYQKNWLE
::::::::::::::::::::::::::
NP_001 ELLEDGSTTGFLQYAYDGQDFLIFNKDTLSWLAVDNVAHTIKQAWEANQHELLYQKNWLE
130 140 150 160 170 180
140 150 160 170 180 190
pF1KE6 EECIAWLKRFLEYGKDTLQRTEPPLVRVNRKETFPGVTALFCKAHGFYPPEIYMTWMKNG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EECIAWLKRFLEYGKDTLQRTEPPLVRVNRKETFPGVTALFCKAHGFYPPEIYMTWMKNG
190 200 210 220 230 240
200 210 220 230 240 250
pF1KE6 EEIVQEIDYGDILPSGDGTYQAWASIELDPQSSNLYSCHVEHCGVHMVLQVPQESETIPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EEIVQEIDYGDILPSGDGTYQAWASIELDPQSSNLYSCHVEHCGVHMVLQVPQESETIPL
250 260 270 280 290 300
260 270 280 290
pF1KE6 VMKAVSGSIVLVIVLAGVGVLVWRRRPREQNGAIYLPTPDR
:::::::::::::::::::::::::::::::::::::::::
NP_001 VMKAVSGSIVLVIVLAGVGVLVWRRRPREQNGAIYLPTPDR
310 320 330 340
>>NP_001181964 (OMIM: 600764) major histocompatibility c (214 aa)
initn: 1075 init1: 754 opt: 761 Z-score: 827.2 bits: 160.6 E(85289): 2.5e-39
Smith-Waterman score: 989; 77.7% identity (77.7% similar) in 202 aa overlap (1-157:1-202)
10 20 30 40 50 60
pF1KE6 MGELMAFLLPLIIVLMVKHSDSRTHSLRYFRLGVSDPIHGVPEFISVGYVDSHPITTYDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MGELMAFLLPLIIVLMVKHSDSRTHSLRYFRLGVSDPIHGVPEFISVGYVDSHPITTYDS
10 20 30 40 50 60
70 80 90 100
pF1KE6 VTRQKEPRAPWMAENLAPDHWERYTQLLRGWQQMFKVELKRLQRHYNHS-----------
:::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VTRQKEPRAPWMAENLAPDHWERYTQLLRGWQQMFKVELKRLQRHYNHSGSHTYQRMIGC
70 80 90 100 110 120
110 120 130
pF1KE6 ----------------------------------DNVAHTIKQAWEANQHELLYQKNWLE
::::::::::::::::::::::::::
NP_001 ELLEDGSTTGFLQYAYDGQDFLIFNKDTLSWLAVDNVAHTIKQAWEANQHELLYQKNWLE
130 140 150 160 170 180
140 150 160 170 180 190
pF1KE6 EECIAWLKRFLEYGKDTLQRTEPPLVRVNRKETFPGVTALFCKAHGFYPPEIYMTWMKNG
::::::::::::::::::::::
NP_001 EECIAWLKRFLEYGKDTLQRTEQNGAIYLPTPDR
190 200 210
>>NP_001181929 (OMIM: 600764) major histocompatibility c (249 aa)
initn: 1076 init1: 754 opt: 759 Z-score: 824.1 bits: 160.2 E(85289): 3.6e-39
Smith-Waterman score: 1097; 59.8% identity (59.8% similar) in 341 aa overlap (1-296:1-249)
10 20 30 40 50 60
pF1KE6 MGELMAFLLPLIIVLMVKHSDSRTHSLRYFRLGVSDPIHGVPEFISVGYVDSHPITTYDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MGELMAFLLPLIIVLMVKHSDSRTHSLRYFRLGVSDPIHGVPEFISVGYVDSHPITTYDS
10 20 30 40 50 60
70 80 90 100
pF1KE6 VTRQKEPRAPWMAENLAPDHWERYTQLLRGWQQMFKVELKRLQRHYNHS-----------
:::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VTRQKEPRAPWMAENLAPDHWERYTQLLRGWQQMFKVELKRLQRHYNHSGSHTYQRMIGC
70 80 90 100 110 120
110 120 130
pF1KE6 ----------------------------------DNVAHTIKQAWEANQHELLYQKNWLE
::::::::::::::::::::::::::
NP_001 ELLEDGSTTGFLQYAYDGQDFLIFNKDTLSWLAVDNVAHTIKQAWEANQHELLYQKNWLE
130 140 150 160 170 180
140 150 160 170 180 190
pF1KE6 EECIAWLKRFLEYGKDTLQRTEPPLVRVNRKETFPGVTALFCKAHGFYPPEIYMTWMKNG
::::::::::::::::::::::
NP_001 EECIAWLKRFLEYGKDTLQRTE--------------------------------------
190 200
200 210 220 230 240 250
pF1KE6 EEIVQEIDYGDILPSGDGTYQAWASIELDPQSSNLYSCHVEHCGVHMVLQVPQESETIPL
::::::
NP_001 ------------------------------------------------------SETIPL
260 270 280 290
pF1KE6 VMKAVSGSIVLVIVLAGVGVLVWRRRPREQNGAIYLPTPDR
:::::::::::::::::::::::::::::::::::::::::
NP_001 VMKAVSGSIVLVIVLAGVGVLVWRRRPREQNGAIYLPTPDR
210 220 230 240
>>XP_006711349 (OMIM: 600764) PREDICTED: major histocomp (312 aa)
initn: 1518 init1: 755 opt: 755 Z-score: 818.5 bits: 159.5 E(85289): 7.5e-39
Smith-Waterman score: 1670; 78.3% identity (78.3% similar) in 341 aa overlap (1-296:1-312)
10 20 30 40 50 60
pF1KE6 MGELMAFLLPLIIVLMVKHSDSRTHSLRYFRLGVSDPIHGVPEFISVGYVDSHPITTYDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MGELMAFLLPLIIVLMVKHSDSRTHSLRYFRLGVSDPIHGVPEFISVGYVDSHPITTYDS
10 20 30 40 50 60
70 80 90 100
pF1KE6 VTRQKEPRAPWMAENLAPDHWERYTQLLRGWQQMFKVELKRLQRHYNHS-----------
:::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 VTRQKEPRAPWMAENLAPDHWERYTQLLRGWQQMFKVELKRLQRHYNHSGSHTYQRMIGC
70 80 90 100 110 120
110 120 130
pF1KE6 ----------------------------------DNVAHTIKQAWEANQHELLYQKNWLE
::::::::::::::::::::::::::
XP_006 ELLEDGSTTGFLQYAYDGQDFLIFNKDTLSWLAVDNVAHTIKQAWEANQHELLYQKNWLE
130 140 150 160 170 180
140 150 160 170 180 190
pF1KE6 EECIAWLKRFLEYGKDTLQRTEPPLVRVNRKETFPGVTALFCKAHGFYPPEIYMTWMKNG
::::::::::::::::::::: ::::::::::
XP_006 EECIAWLKRFLEYGKDTLQRT-----------------------------EIYMTWMKNG
190 200 210
200 210 220 230 240 250
pF1KE6 EEIVQEIDYGDILPSGDGTYQAWASIELDPQSSNLYSCHVEHCGVHMVLQVPQESETIPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 EEIVQEIDYGDILPSGDGTYQAWASIELDPQSSNLYSCHVEHCGVHMVLQVPQESETIPL
220 230 240 250 260 270
260 270 280 290
pF1KE6 VMKAVSGSIVLVIVLAGVGVLVWRRRPREQNGAIYLPTPDR
:::::::::::::::::::::::::::::::::::::::::
XP_006 VMKAVSGSIVLVIVLAGVGVLVWRRRPREQNGAIYLPTPDR
280 290 300 310
>>NP_002107 (OMIM: 142800,608579) HLA class I histocompa (365 aa)
initn: 569 init1: 348 opt: 454 Z-score: 495.3 bits: 100.0 E(85289): 7.5e-21
Smith-Waterman score: 580; 32.6% identity (59.3% similar) in 322 aa overlap (24-290:26-344)
10 20 30 40 50
pF1KE6 MGELMAFLLPLIIVLMVKHSDSRTHSLRYFRLGVSDPIHGVPEFISVGYVDSHPITTY
.::.::: .:: : .: :.::.:::::. .. .
NP_002 MAVMAPRTLLLLLSGALALTQTWAGSHSMRYFFTSVSRPGRGEPRFIAVGYVDDTQFVRF
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE6 DS--VTRQKEPRAPWMAENLAPDHWERYTQLLRGWQQMFKVELKRLQRHYNHSDNVAHTI
:: .... ::::::. :. .:..:.. :. ... .: .:.: :. .::.:. .:::
NP_002 DSDAASQRMEPRAPWI-EQEGPEYWDQETRNVKAQSQTDRVDLGTLRGYYNQSEAGSHTI
70 80 90 100 110
120
pF1KE6 ------------------------------------------------KQAWEANQHELL
:. ::: ::
NP_002 QIMYGCDVGSDGRFLRGYRQDAYDGKDYIALNEDLRSWTAADMAAQITKRKWEAA-HEAE
120 130 140 150 160 170
130 140 150 160 170 180
pF1KE6 YQKNWLEEECIAWLKRFLEYGKDTLQRTEPPLVRVNRKETFPGVTALFCKAHGFYPPEIY
. .:. :. ::.:.:: ::.:::::.:: ...... ..: : : :::: ::
NP_002 QLRAYLDGTCVEWLRRYLENGKETLQRTDPPKTHMTHHPISDHEATLRCWALGFYPAEIT
180 190 200 210 220 230
190 200 210 220 230 240
pF1KE6 MTWMKNGEEIVQEIDYGDILPSGDGTYQAWASIELDPQSSNLYSCHVEHCGVHMVLQVPQ
.::...::. .:. . . :.::::.: ::.. . . :.:::.: :. : .
NP_002 LTWQRDGEDQTQDTELVETRPAGDGTFQKWAAVVVPSGEEQRYTCHVQHEGLPKPLTLRW
240 250 260 270 280 290
250 260 270 280 290
pF1KE6 E---SETIPLVMKAVSGSIVLVIVLAG--VGVLVWRRRPREQNGAIYLPTPDR
: . :::.: ..: ..: :..: :....:::. ...:. :
NP_002 ELSSQPTIPIV-GIIAGLVLLGAVITGAVVAAVMWRRKSSDRKGGSYTQAASSDSAQGSD
300 310 320 330 340 350
NP_002 VSLTACKV
360
>>XP_016866304 (OMIM: 143110) PREDICTED: HLA class I his (228 aa)
initn: 404 init1: 341 opt: 450 Z-score: 493.9 bits: 99.0 E(85289): 9e-21
Smith-Waterman score: 450; 34.5% identity (65.9% similar) in 226 aa overlap (75-290:5-223)
50 60 70 80 90
pF1KE6 ISVGYVDSHPITTYDSVTRQKEPRAPWMAENLAPDHWERYTQLLRGWQQMFK-----VEL
...:: .::::..: . :
XP_016 MNGCDMGPDG-----RLLRGYHQHAYDGKDYISL
10 20
100 110 120 130 140 150
pF1KE6 KRLQRHYNHSDNVAHTIKQAWEANQHELLYQKNWLEEECIAWLKRFLEYGKDTLQRTEPP
.. : .. .:.::. .. .::... . ...:: ::. :.:.:: ::.::::..::
XP_016 NEDLRSWTAADTVAQITQRFYEAEEYAEEF-RTYLEGECLELLRRYLENGKETLQRADPP
30 40 50 60 70 80
160 170 180 190 200 210
pF1KE6 LVRVNRKETFPGVTALFCKAHGFYPPEIYMTWMKNGEEIVQEIDYGDILPSGDGTYQAWA
..: .. ..: : : :::: :: .::...::: .:. . . :.::::.: ::
XP_016 KAHVAHHPISDHEATLRCWALGFYPAEITLTWQRDGEEQTQDTELVETRPAGDGTFQKWA
90 100 110 120 130 140
220 230 240 250 260 270
pF1KE6 SIELDPQSSNLYSCHVEHCGVH--MVLQVPQESE-TIPLVMKAVSGSIVLVIVLAG--VG
.. . : . :.:::.: :. ..:. : . :::.: :.: .:: :..: :.
XP_016 AVVVPPGEEQRYTCHVQHEGLPQPLILRWEQSPQPTIPIV-GIVAGLVVLGAVVTGAVVA
150 160 170 180 190 200
280 290
pF1KE6 VLVWRRRPREQNGAIYLPTPDR
...::.. ..: . :
XP_016 AVMWRKKSSDRNRGSYSQAAV
210 220
>>XP_016866303 (OMIM: 143110) PREDICTED: HLA class I his (324 aa)
initn: 364 init1: 341 opt: 450 Z-score: 491.8 bits: 99.1 E(85289): 1.2e-20
Smith-Waterman score: 450; 34.5% identity (65.9% similar) in 226 aa overlap (75-290:5-223)
50 60 70 80 90
pF1KE6 ISVGYVDSHPITTYDSVTRQKEPRAPWMAENLAPDHWERYTQLLRGWQQMFK-----VEL
...:: .::::..: . :
XP_016 MNGCDMGPDG-----RLLRGYHQHAYDGKDYISL
10 20
100 110 120 130 140 150
pF1KE6 KRLQRHYNHSDNVAHTIKQAWEANQHELLYQKNWLEEECIAWLKRFLEYGKDTLQRTEPP
.. : .. .:.::. .. .::... . ...:: ::. :.:.:: ::.::::..::
XP_016 NEDLRSWTAADTVAQITQRFYEAEEYAEEF-RTYLEGECLELLRRYLENGKETLQRADPP
30 40 50 60 70 80
160 170 180 190 200 210
pF1KE6 LVRVNRKETFPGVTALFCKAHGFYPPEIYMTWMKNGEEIVQEIDYGDILPSGDGTYQAWA
..: .. ..: : : :::: :: .::...::: .:. . . :.::::.: ::
XP_016 KAHVAHHPISDHEATLRCWALGFYPAEITLTWQRDGEEQTQDTELVETRPAGDGTFQKWA
90 100 110 120 130 140
220 230 240 250 260 270
pF1KE6 SIELDPQSSNLYSCHVEHCGVH--MVLQVPQESE-TIPLVMKAVSGSIVLVIVLAG--VG
.. . : . :.:::.: :. ..:. : . :::.: :.: .:: :..: :.
XP_016 AVVVPPGEEQRYTCHVQHEGLPQPLILRWEQSPQPTIPIV-GIVAGLVVLGAVVTGAVVA
150 160 170 180 190 200
280 290
pF1KE6 VLVWRRRPREQNGAIYLPTPDR
...::.. ..: . :
XP_016 AVMWRKKSSDRNRGSYSQAAAYSVVSGNLMITWWSSLFLLGVLFQGYLGCLRSHSVLGRR
210 220 230 240 250 260
>>NP_061823 (OMIM: 143110) HLA class I histocompatibilit (346 aa)
initn: 546 init1: 341 opt: 450 Z-score: 491.4 bits: 99.1 E(85289): 1.2e-20
Smith-Waterman score: 542; 32.9% identity (58.4% similar) in 322 aa overlap (24-290:23-341)
10 20 30 40 50 60
pF1KE6 MGELMAFLLPLIIVLMVKHSDSRTHSLRYFRLGVSDPIHGVPEFISVGYVDSHPITTYDS
.:::::: .:: : .: :..:.: :::. . .::
NP_061 MAPRSLLLLLSGALALTDTWAGSHSLRYFSTAVSRPGRGEPRYIAVEYVDDTQFLRFDS
10 20 30 40 50
70 80 90 100 110
pF1KE6 ---VTRQKEPRAPWMAENLAPDHWERYTQLLRGWQQMFKVELKRLQRHYNHSDNVAHTIK
. :. ::: ::. :. .:..:: : .. : .: :. : :.::.:. .::..
NP_061 DAAIPRM-EPREPWV-EQEGPQYWEWTTGYAKANAQTDRVALRNLLRRYNQSEAGSHTLQ
60 70 80 90 100 110
120 130
pF1KE6 ----------------------------------QAWEANQH-----ELLYQ--------
..: : . . .:.
NP_061 GMNGCDMGPDGRLLRGYHQHAYDGKDYISLNEDLRSWTAADTVAQITQRFYEAEEYAEEF
120 130 140 150 160 170
140 150 160 170 180 190
pF1KE6 KNWLEEECIAWLKRFLEYGKDTLQRTEPPLVRVNRKETFPGVTALFCKAHGFYPPEIYMT
...:: ::. :.:.:: ::.::::..:: ..: .. ..: : : :::: :: .:
NP_061 RTYLEGECLELLRRYLENGKETLQRADPPKAHVAHHPISDHEATLRCWALGFYPAEITLT
180 190 200 210 220 230
200 210 220 230 240
pF1KE6 WMKNGEEIVQEIDYGDILPSGDGTYQAWASIELDPQSSNLYSCHVEHCGVH--MVLQVPQ
:...::: .:. . . :.::::.: ::.. . : . :.:::.: :. ..:. :
NP_061 WQRDGEEQTQDTELVETRPAGDGTFQKWAAVVVPPGEEQRYTCHVQHEGLPQPLILRWEQ
240 250 260 270 280 290
250 260 270 280 290
pF1KE6 ESE-TIPLVMKAVSGSIVLVIVLAG--VGVLVWRRRPREQNGAIYLPTPDR
. :::.: :.: .:: :..: :....::.. ..: . :
NP_061 SPQPTIPIV-GIVAGLVVLGAVVTGAVVAAVMWRKKSSDRNRGSYSQAAV
300 310 320 330 340
296 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Nov 8 15:17:37 2016 done: Tue Nov 8 15:17:38 2016
Total Scan time: 5.410 Total Display time: 0.010
Function used was FASTA [36.3.4 Apr, 2011]