FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KE6664, 283 aa
  1>>>pF1KE6664 283 - 283 aa - 283 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 5.4246+/-0.000399; mu= 13.5003+/- 0.025
 mean_var=57.5280+/-11.541, 0's: 0 Z-trim(110.9): 17  B-trim: 112 in 1/53
 Lambda= 0.169096
 statistics sampled from 19305 (19317) to 19305 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.604), E-opt: 0.2 (0.226), width:  16
 Scan time:  6.760

The best scores are:                                      opt bits E(85289)
NP_002442 (OMIM: 156540) S-methyl-5'-thioadenosine ( 283) 1888 469.1 4.2e-132
NP_000261 (OMIM: 164050,613179) purine nucleoside  ( 289)  273 75.1 1.7e-13


>>NP_002442 (OMIM: 156540) S-methyl-5'-thioadenosine pho  (283 aa)
 initn: 1888 init1: 1888 opt: 1888  Z-score: 2492.6  bits: 469.1 E(85289): 4.2e-132
Smith-Waterman score: 1888; 99.6% identity (100.0% similar) in 283 aa overlap (1-283:1-283)

               10        20        30        40        50        60
pF1KE6 MASGTTTTAVKIGIIGGTGLDDPEILEGRTEKYVDTPFGKPSDALILGKIKNVDCILLAR
       :::::::::::::::::::::::::::::::::::::::::::::::::::::::.::::
NP_002 MASGTTTTAVKIGIIGGTGLDDPEILEGRTEKYVDTPFGKPSDALILGKIKNVDCVLLAR
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE6 HGRQHTIMPSKVNYQANIWALKEEGCTHVIVTTACGSLREEIQPGDIVIIDQFIDRTTMR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 HGRQHTIMPSKVNYQANIWALKEEGCTHVIVTTACGSLREEIQPGDIVIIDQFIDRTTMR
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE6 PQSFYDGSHSCARGVCHIPMAEPFCPKTREVLIETAKKLGLRCHSKGTMVTIEGPRFSSR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 PQSFYDGSHSCARGVCHIPMAEPFCPKTREVLIETAKKLGLRCHSKGTMVTIEGPRFSSR
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KE6 AESFMFRTWGADVINMTTVPEVVLAKEAGICYASIAMATDYDCWKEHEEAVSVDRVLKTL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 AESFMFRTWGADVINMTTVPEVVLAKEAGICYASIAMATDYDCWKEHEEAVSVDRVLKTL
              190       200       210       220       230       240

              250       260       270       280   
pF1KE6 KENANKAKSLLLTTIPQIGSTEWSETLHNLKNMAQFSVLLPRH
       :::::::::::::::::::::::::::::::::::::::::::
NP_002 KENANKAKSLLLTTIPQIGSTEWSETLHNLKNMAQFSVLLPRH
              250       260       270       280   

>>NP_000261 (OMIM: 164050,613179) purine nucleoside phos  (289 aa)
 initn: 181 init1: 137 opt: 273  Z-score: 363.2  bits: 75.1 E(85289): 1.7e-13
Smith-Waterman score: 273; 27.1% identity (58.8% similar) in 262 aa overlap (11-256:26-283)

                              10        20          30         40  
pF1KE6                MASGTTTTAVKIGIIGGTGLDD--PEILEGRTEKYVDTP-FGK--
                                ...:: :.::     .. ...   : . : : .  
NP_000 MENGYTYEDYKNTAEWLLSHTKHRPQVAIICGSGLGGLTDKLTQAQIFDYGEIPNFPRST
               10        20        30        40        50        60

                  50        60          70         80        90    
pF1KE6 -PSDA--LILGKIKNVDCILLARHGRQHTI--MPS-KVNYQANIWALKEEGCTHVIVTTA
        :. :  :..: ...  :...  .:: :    .:  ::.. . .. :   :   ..::.:
NP_000 VPGHAGRLVFGFLNGRACVMM--QGRFHMYEGYPLWKVTFPVRVFHLL--GVDTLVVTNA
               70        80          90       100         110      

          100       110       120       130       140       150    
pF1KE6 CGSLREEIQPGDIVIIDQFIDRTTMRPQSFYDGSHSCARGVCHIPMAEPFCPKTREVLIE
        :.:  ... :::..: . :.   .  :.   : ..   :     :.. .    :.  . 
NP_000 AGGLNPKFEVGDIMLIRDHINLPGFSGQNPLRGPNDERFGDRFPAMSDAYDRTMRQRALS
        120       130       140       150       160       170      

          160        170       180       190       200       210   
pF1KE6 TAKKLG-LRCHSKGTMVTIEGPRFSSRAESFMFRTWGADVINMTTVPEVVLAKEAGICYA
       : :..:  :  ..::.: . :: : . ::  ...  :::...:.:::::..:.. :.   
NP_000 TWKQMGEQRELQEGTYVMVAGPSFETVAECRVLQKLGADAVGMSTVPEVIVARHCGLRVF
        180       190       200       210       220       230      

           220        230       240          250       260         
pF1KE6 SIAMATDYDCWK-EHEEAVSVDRVLKTLKENANKAK---SLLLTTIPQIGSTEWSETLHN
       .... :.      :  : .. ..:: . :. :.: .   :.:...::             
NP_000 GFSLITNKVIMDYESLEKANHEEVLAAGKQAAQKLEQFVSILMASIPLPDKAS       
        240       250       260       270       280                

     270       280   
pF1KE6 LKNMAQFSVLLPRH




283 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Tue Nov  8 15:14:01 2016 done: Tue Nov  8 15:14:02 2016
 Total Scan time:  6.760 Total Display time: -0.020

Function used was FASTA [36.3.4 Apr, 2011]