Result of FASTA (omim) for
pFN21AE6663
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE6663, 285 aa
1>>>pF1KE6663 285 - 285 aa - 285 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.3020+/-0.000277; mu= 16.2401+/- 0.017
mean_var=74.7333+/-15.189, 0's: 0 Z-trim(119.6): 11 B-trim: 174 in 2/54
Lambda= 0.148360
statistics sampled from 33816 (33829) to 33816 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.765), E-opt: 0.2 (0.397), width: 16
Scan time: 7.150
The best scores are: opt bits E(85289)
NP_039268 (OMIM: 604744) N(G),N(G)-dimethylarginin ( 285) 1901 415.5 5.9e-116
NP_001289936 (OMIM: 604744) N(G),N(G)-dimethylargi ( 285) 1901 415.5 5.9e-116
NP_001289937 (OMIM: 604744) N(G),N(G)-dimethylargi ( 285) 1901 415.5 5.9e-116
XP_011512750 (OMIM: 604744) PREDICTED: N(G),N(G)-d ( 285) 1901 415.5 5.9e-116
NP_036269 (OMIM: 604743) N(G),N(G)-dimethylarginin ( 285) 899 201.0 2.1e-51
XP_016856378 (OMIM: 604743) PREDICTED: N(G),N(G)-d ( 192) 635 144.4 1.6e-34
NP_001317584 (OMIM: 604743) N(G),N(G)-dimethylargi ( 185) 633 143.9 2.1e-34
XP_011539460 (OMIM: 604743) PREDICTED: N(G),N(G)-d ( 185) 633 143.9 2.1e-34
XP_005270764 (OMIM: 604743) PREDICTED: N(G),N(G)-d ( 190) 633 143.9 2.1e-34
NP_001127917 (OMIM: 604743) N(G),N(G)-dimethylargi ( 182) 623 141.8 9.2e-34
XP_005270767 (OMIM: 604743) PREDICTED: N(G),N(G)-d ( 182) 623 141.8 9.2e-34
>>NP_039268 (OMIM: 604744) N(G),N(G)-dimethylarginine di (285 aa)
initn: 1901 init1: 1901 opt: 1901 Z-score: 2202.8 bits: 415.5 E(85289): 5.9e-116
Smith-Waterman score: 1901; 100.0% identity (100.0% similar) in 285 aa overlap (1-285:1-285)
10 20 30 40 50 60
pF1KE6 MGTPGEGLGRCSHALIRGVPESLASGEGAGAGLPALDLAKAQREHGVLGGKLRQRLGLQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_039 MGTPGEGLGRCSHALIRGVPESLASGEGAGAGLPALDLAKAQREHGVLGGKLRQRLGLQL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 LELPPEESLPLGPLLGDTAVIQGDTALITRPWSPARRPEVDGVRKALQDLGLRIVEIGDE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_039 LELPPEESLPLGPLLGDTAVIQGDTALITRPWSPARRPEVDGVRKALQDLGLRIVEIGDE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 NATLDGTDVLFTGREFFVGLSKWTNHRGAEIVADTFRDFAVSTVPVSGPSHLRGLCGMGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_039 NATLDGTDVLFTGREFFVGLSKWTNHRGAEIVADTFRDFAVSTVPVSGPSHLRGLCGMGG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE6 PRTVVAGSSDAAQKAVRAMAVLTDHPYASLTLPDDAAADCLFLRPGLPGVPPFLLHRGGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_039 PRTVVAGSSDAAQKAVRAMAVLTDHPYASLTLPDDAAADCLFLRPGLPGVPPFLLHRGGG
190 200 210 220 230 240
250 260 270 280
pF1KE6 DLPNSQEALQKLSDVTLVPVSCSELEKAGAGLSSLCLVLSTRPHS
:::::::::::::::::::::::::::::::::::::::::::::
NP_039 DLPNSQEALQKLSDVTLVPVSCSELEKAGAGLSSLCLVLSTRPHS
250 260 270 280
>>NP_001289936 (OMIM: 604744) N(G),N(G)-dimethylarginine (285 aa)
initn: 1901 init1: 1901 opt: 1901 Z-score: 2202.8 bits: 415.5 E(85289): 5.9e-116
Smith-Waterman score: 1901; 100.0% identity (100.0% similar) in 285 aa overlap (1-285:1-285)
10 20 30 40 50 60
pF1KE6 MGTPGEGLGRCSHALIRGVPESLASGEGAGAGLPALDLAKAQREHGVLGGKLRQRLGLQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MGTPGEGLGRCSHALIRGVPESLASGEGAGAGLPALDLAKAQREHGVLGGKLRQRLGLQL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 LELPPEESLPLGPLLGDTAVIQGDTALITRPWSPARRPEVDGVRKALQDLGLRIVEIGDE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LELPPEESLPLGPLLGDTAVIQGDTALITRPWSPARRPEVDGVRKALQDLGLRIVEIGDE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 NATLDGTDVLFTGREFFVGLSKWTNHRGAEIVADTFRDFAVSTVPVSGPSHLRGLCGMGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NATLDGTDVLFTGREFFVGLSKWTNHRGAEIVADTFRDFAVSTVPVSGPSHLRGLCGMGG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE6 PRTVVAGSSDAAQKAVRAMAVLTDHPYASLTLPDDAAADCLFLRPGLPGVPPFLLHRGGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PRTVVAGSSDAAQKAVRAMAVLTDHPYASLTLPDDAAADCLFLRPGLPGVPPFLLHRGGG
190 200 210 220 230 240
250 260 270 280
pF1KE6 DLPNSQEALQKLSDVTLVPVSCSELEKAGAGLSSLCLVLSTRPHS
:::::::::::::::::::::::::::::::::::::::::::::
NP_001 DLPNSQEALQKLSDVTLVPVSCSELEKAGAGLSSLCLVLSTRPHS
250 260 270 280
>>NP_001289937 (OMIM: 604744) N(G),N(G)-dimethylarginine (285 aa)
initn: 1901 init1: 1901 opt: 1901 Z-score: 2202.8 bits: 415.5 E(85289): 5.9e-116
Smith-Waterman score: 1901; 100.0% identity (100.0% similar) in 285 aa overlap (1-285:1-285)
10 20 30 40 50 60
pF1KE6 MGTPGEGLGRCSHALIRGVPESLASGEGAGAGLPALDLAKAQREHGVLGGKLRQRLGLQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MGTPGEGLGRCSHALIRGVPESLASGEGAGAGLPALDLAKAQREHGVLGGKLRQRLGLQL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 LELPPEESLPLGPLLGDTAVIQGDTALITRPWSPARRPEVDGVRKALQDLGLRIVEIGDE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LELPPEESLPLGPLLGDTAVIQGDTALITRPWSPARRPEVDGVRKALQDLGLRIVEIGDE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 NATLDGTDVLFTGREFFVGLSKWTNHRGAEIVADTFRDFAVSTVPVSGPSHLRGLCGMGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NATLDGTDVLFTGREFFVGLSKWTNHRGAEIVADTFRDFAVSTVPVSGPSHLRGLCGMGG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE6 PRTVVAGSSDAAQKAVRAMAVLTDHPYASLTLPDDAAADCLFLRPGLPGVPPFLLHRGGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PRTVVAGSSDAAQKAVRAMAVLTDHPYASLTLPDDAAADCLFLRPGLPGVPPFLLHRGGG
190 200 210 220 230 240
250 260 270 280
pF1KE6 DLPNSQEALQKLSDVTLVPVSCSELEKAGAGLSSLCLVLSTRPHS
:::::::::::::::::::::::::::::::::::::::::::::
NP_001 DLPNSQEALQKLSDVTLVPVSCSELEKAGAGLSSLCLVLSTRPHS
250 260 270 280
>>XP_011512750 (OMIM: 604744) PREDICTED: N(G),N(G)-dimet (285 aa)
initn: 1901 init1: 1901 opt: 1901 Z-score: 2202.8 bits: 415.5 E(85289): 5.9e-116
Smith-Waterman score: 1901; 100.0% identity (100.0% similar) in 285 aa overlap (1-285:1-285)
10 20 30 40 50 60
pF1KE6 MGTPGEGLGRCSHALIRGVPESLASGEGAGAGLPALDLAKAQREHGVLGGKLRQRLGLQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MGTPGEGLGRCSHALIRGVPESLASGEGAGAGLPALDLAKAQREHGVLGGKLRQRLGLQL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 LELPPEESLPLGPLLGDTAVIQGDTALITRPWSPARRPEVDGVRKALQDLGLRIVEIGDE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LELPPEESLPLGPLLGDTAVIQGDTALITRPWSPARRPEVDGVRKALQDLGLRIVEIGDE
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 NATLDGTDVLFTGREFFVGLSKWTNHRGAEIVADTFRDFAVSTVPVSGPSHLRGLCGMGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NATLDGTDVLFTGREFFVGLSKWTNHRGAEIVADTFRDFAVSTVPVSGPSHLRGLCGMGG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE6 PRTVVAGSSDAAQKAVRAMAVLTDHPYASLTLPDDAAADCLFLRPGLPGVPPFLLHRGGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PRTVVAGSSDAAQKAVRAMAVLTDHPYASLTLPDDAAADCLFLRPGLPGVPPFLLHRGGG
190 200 210 220 230 240
250 260 270 280
pF1KE6 DLPNSQEALQKLSDVTLVPVSCSELEKAGAGLSSLCLVLSTRPHS
:::::::::::::::::::::::::::::::::::::::::::::
XP_011 DLPNSQEALQKLSDVTLVPVSCSELEKAGAGLSSLCLVLSTRPHS
250 260 270 280
>>NP_036269 (OMIM: 604743) N(G),N(G)-dimethylarginine di (285 aa)
initn: 915 init1: 778 opt: 899 Z-score: 1043.7 bits: 201.0 E(85289): 2.1e-51
Smith-Waterman score: 899; 52.0% identity (77.1% similar) in 279 aa overlap (1-279:4-278)
10 20 30 40 50
pF1KE6 MGTPGEGLGRCSHALIRGVPESLASGEGAGAGLPALDLAKAQREHGVLGGKLRQRLG
.: :. ..:: .::..:..::::.. .: .:.:.:.:.: . : : ..::
NP_036 MAGLGHPA-AFGRATHAVVRALPESLGQHALRSAKGEEVDVARAERQHQLYVGVLGSKLG
10 20 30 40 50
60 70 80 90 100 110
pF1KE6 LQLLELPPEESLPLGPLLGDTAVIQGDTALITRPWSPARRPEVDGVRKALQDLGLRIVEI
::..::: .:::: .. :.::. .::::::: .:.:: ::: ...::. : : :::.
NP_036 LQVVELPADESLPDCVFVEDVAVVCEETALITRPGAPSRRKEVDMMKEALEKLQLNIVEM
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE6 GDENATLDGTDVLFTGREFFVGLSKWTNHRGAEIVADTFRDFAVSTVPVSGPSHLRGLCG
:::::::: ::::::::::::::: ::.:::::.::::.:.:::::::. ::...:.
NP_036 KDENATLDGGDVLFTGREFFVGLSKRTNQRGAEILADTFKDYAVSTVPVADGLHLKSFCS
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE6 MGGPRTVVAGSSDAAQKAVRAMAVLTDHPYASLTLPDDAAADCLFLRPGLPGVPPFLLHR
:.:: .. :::..::::.. : ..:: : .::.::: ::.:..: ..:. ::::
NP_036 MAGPNLIAIGSSESAQKALKIMQQMSDHRYDKLTVPDDIAANCIYL--NIPNKGHVLLHR
180 190 200 210 220 230
240 250 260 270 280
pF1KE6 GGGDLPNSQEALQKLSDVTLVPVSCSELEKAGAGLSSLCLVLSTRPHS
. :.: .. .::.: :.::: :::::. :: . : ::
NP_036 TPEEYPESAKVYEKLKDHMLIPVSMSELEKVD-GLLTCCSVLINKKVDS
240 250 260 270 280
>>XP_016856378 (OMIM: 604743) PREDICTED: N(G),N(G)-dimet (192 aa)
initn: 628 init1: 520 opt: 635 Z-score: 740.7 bits: 144.4 E(85289): 1.6e-34
Smith-Waterman score: 635; 55.8% identity (78.5% similar) in 181 aa overlap (99-279:8-185)
70 80 90 100 110 120
pF1KE6 LPLGPLLGDTAVIQGDTALITRPWSPARRPEVDGVRKALQDLGLRIVEIGDENATLDGTD
.:: ...::. : : :::. :::::::: :
XP_016 MWLYGLGQVDMMKEALEKLQLNIVEMKDENATLDGGD
10 20 30
130 140 150 160 170 180
pF1KE6 VLFTGREFFVGLSKWTNHRGAEIVADTFRDFAVSTVPVSGPSHLRGLCGMGGPRTVVAGS
:::::::::::::: ::.:::::.::::.:.:::::::. ::...:.:.:: .. ::
XP_016 VLFTGREFFVGLSKRTNQRGAEILADTFKDYAVSTVPVADGLHLKSFCSMAGPNLIAIGS
40 50 60 70 80 90
190 200 210 220 230 240
pF1KE6 SDAAQKAVRAMAVLTDHPYASLTLPDDAAADCLFLRPGLPGVPPFLLHRGGGDLPNSQEA
:..::::.. : ..:: : .::.::: ::.:..: ..:. :::: . :.: ..
XP_016 SESAQKALKIMQQMSDHRYDKLTVPDDIAANCIYL--NIPNKGHVLLHRTPEEYPESAKV
100 110 120 130 140 150
250 260 270 280
pF1KE6 LQKLSDVTLVPVSCSELEKAGAGLSSLCLVLSTRPHS
.::.: :.::: :::::. :: . : ::
XP_016 YEKLKDHMLIPVSMSELEKVD-GLLTCCSVLINKKVDS
160 170 180 190
>>NP_001317584 (OMIM: 604743) N(G),N(G)-dimethylarginine (185 aa)
initn: 628 init1: 520 opt: 633 Z-score: 738.6 bits: 143.9 E(85289): 2.1e-34
Smith-Waterman score: 633; 56.1% identity (78.3% similar) in 180 aa overlap (100-279:2-178)
70 80 90 100 110 120
pF1KE6 PLGPLLGDTAVIQGDTALITRPWSPARRPEVDGVRKALQDLGLRIVEIGDENATLDGTDV
:: ...::. : : :::. :::::::: ::
NP_001 MVDMMKEALEKLQLNIVEMKDENATLDGGDV
10 20 30
130 140 150 160 170 180
pF1KE6 LFTGREFFVGLSKWTNHRGAEIVADTFRDFAVSTVPVSGPSHLRGLCGMGGPRTVVAGSS
::::::::::::: ::.:::::.::::.:.:::::::. ::...:.:.:: .. :::
NP_001 LFTGREFFVGLSKRTNQRGAEILADTFKDYAVSTVPVADGLHLKSFCSMAGPNLIAIGSS
40 50 60 70 80 90
190 200 210 220 230 240
pF1KE6 DAAQKAVRAMAVLTDHPYASLTLPDDAAADCLFLRPGLPGVPPFLLHRGGGDLPNSQEAL
..::::.. : ..:: : .::.::: ::.:..: ..:. :::: . :.: ..
NP_001 ESAQKALKIMQQMSDHRYDKLTVPDDIAANCIYL--NIPNKGHVLLHRTPEEYPESAKVY
100 110 120 130 140
250 260 270 280
pF1KE6 QKLSDVTLVPVSCSELEKAGAGLSSLCLVLSTRPHS
.::.: :.::: :::::. :: . : ::
NP_001 EKLKDHMLIPVSMSELEKVD-GLLTCCSVLINKKVDS
150 160 170 180
>>XP_011539460 (OMIM: 604743) PREDICTED: N(G),N(G)-dimet (185 aa)
initn: 628 init1: 520 opt: 633 Z-score: 738.6 bits: 143.9 E(85289): 2.1e-34
Smith-Waterman score: 633; 56.1% identity (78.3% similar) in 180 aa overlap (100-279:2-178)
70 80 90 100 110 120
pF1KE6 PLGPLLGDTAVIQGDTALITRPWSPARRPEVDGVRKALQDLGLRIVEIGDENATLDGTDV
:: ...::. : : :::. :::::::: ::
XP_011 MVDMMKEALEKLQLNIVEMKDENATLDGGDV
10 20 30
130 140 150 160 170 180
pF1KE6 LFTGREFFVGLSKWTNHRGAEIVADTFRDFAVSTVPVSGPSHLRGLCGMGGPRTVVAGSS
::::::::::::: ::.:::::.::::.:.:::::::. ::...:.:.:: .. :::
XP_011 LFTGREFFVGLSKRTNQRGAEILADTFKDYAVSTVPVADGLHLKSFCSMAGPNLIAIGSS
40 50 60 70 80 90
190 200 210 220 230 240
pF1KE6 DAAQKAVRAMAVLTDHPYASLTLPDDAAADCLFLRPGLPGVPPFLLHRGGGDLPNSQEAL
..::::.. : ..:: : .::.::: ::.:..: ..:. :::: . :.: ..
XP_011 ESAQKALKIMQQMSDHRYDKLTVPDDIAANCIYL--NIPNKGHVLLHRTPEEYPESAKVY
100 110 120 130 140
250 260 270 280
pF1KE6 QKLSDVTLVPVSCSELEKAGAGLSSLCLVLSTRPHS
.::.: :.::: :::::. :: . : ::
XP_011 EKLKDHMLIPVSMSELEKVD-GLLTCCSVLINKKVDS
150 160 170 180
>>XP_005270764 (OMIM: 604743) PREDICTED: N(G),N(G)-dimet (190 aa)
initn: 628 init1: 520 opt: 633 Z-score: 738.5 bits: 143.9 E(85289): 2.1e-34
Smith-Waterman score: 633; 56.1% identity (78.3% similar) in 180 aa overlap (100-279:7-183)
70 80 90 100 110 120
pF1KE6 PLGPLLGDTAVIQGDTALITRPWSPARRPEVDGVRKALQDLGLRIVEIGDENATLDGTDV
:: ...::. : : :::. :::::::: ::
XP_005 MCKCLWVDMMKEALEKLQLNIVEMKDENATLDGGDV
10 20 30
130 140 150 160 170 180
pF1KE6 LFTGREFFVGLSKWTNHRGAEIVADTFRDFAVSTVPVSGPSHLRGLCGMGGPRTVVAGSS
::::::::::::: ::.:::::.::::.:.:::::::. ::...:.:.:: .. :::
XP_005 LFTGREFFVGLSKRTNQRGAEILADTFKDYAVSTVPVADGLHLKSFCSMAGPNLIAIGSS
40 50 60 70 80 90
190 200 210 220 230 240
pF1KE6 DAAQKAVRAMAVLTDHPYASLTLPDDAAADCLFLRPGLPGVPPFLLHRGGGDLPNSQEAL
..::::.. : ..:: : .::.::: ::.:..: ..:. :::: . :.: ..
XP_005 ESAQKALKIMQQMSDHRYDKLTVPDDIAANCIYL--NIPNKGHVLLHRTPEEYPESAKVY
100 110 120 130 140 150
250 260 270 280
pF1KE6 QKLSDVTLVPVSCSELEKAGAGLSSLCLVLSTRPHS
.::.: :.::: :::::. :: . : ::
XP_005 EKLKDHMLIPVSMSELEKVD-GLLTCCSVLINKKVDS
160 170 180 190
>>NP_001127917 (OMIM: 604743) N(G),N(G)-dimethylarginine (182 aa)
initn: 613 init1: 505 opt: 623 Z-score: 727.2 bits: 141.8 E(85289): 9.2e-34
Smith-Waterman score: 623; 55.9% identity (78.5% similar) in 177 aa overlap (103-279:2-175)
80 90 100 110 120 130
pF1KE6 PLLGDTAVIQGDTALITRPWSPARRPEVDGVRKALQDLGLRIVEIGDENATLDGTDVLFT
...::. : : :::. :::::::: :::::
NP_001 MMKEALEKLQLNIVEMKDENATLDGGDVLFT
10 20 30
140 150 160 170 180 190
pF1KE6 GREFFVGLSKWTNHRGAEIVADTFRDFAVSTVPVSGPSHLRGLCGMGGPRTVVAGSSDAA
:::::::::: ::.:::::.::::.:.:::::::. ::...:.:.:: .. :::..:
NP_001 GREFFVGLSKRTNQRGAEILADTFKDYAVSTVPVADGLHLKSFCSMAGPNLIAIGSSESA
40 50 60 70 80 90
200 210 220 230 240 250
pF1KE6 QKAVRAMAVLTDHPYASLTLPDDAAADCLFLRPGLPGVPPFLLHRGGGDLPNSQEALQKL
:::.. : ..:: : .::.::: ::.:..: ..:. :::: . :.: .. .::
NP_001 QKALKIMQQMSDHRYDKLTVPDDIAANCIYL--NIPNKGHVLLHRTPEEYPESAKVYEKL
100 110 120 130 140
260 270 280
pF1KE6 SDVTLVPVSCSELEKAGAGLSSLCLVLSTRPHS
.: :.::: :::::. :: . : ::
NP_001 KDHMLIPVSMSELEKVD-GLLTCCSVLINKKVDS
150 160 170 180
285 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Nov 8 15:13:21 2016 done: Tue Nov 8 15:13:22 2016
Total Scan time: 7.150 Total Display time: 0.000
Function used was FASTA [36.3.4 Apr, 2011]