Result of FASTA (omim) for
pFN21AE6661
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE6661, 274 aa
1>>>pF1KE6661 274 - 274 aa - 274 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.7043+/-0.000355; mu= 12.9989+/- 0.022
mean_var=70.6406+/-13.914, 0's: 0 Z-trim(113.6): 22 B-trim: 33 in 1/52
Lambda= 0.152597
statistics sampled from 23009 (23018) to 23009 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.647), E-opt: 0.2 (0.27), width: 16
Scan time: 4.680
The best scores are: opt bits E(85289)
NP_002052 (OMIM: 601176,608446) glutamate--cystein ( 274) 1802 405.7 4.7e-113
XP_016856545 (OMIM: 601176,608446) PREDICTED: glut ( 275) 1450 328.2 1e-89
NP_001295182 (OMIM: 601176,608446) glutamate--cyst ( 252) 1368 310.2 2.5e-84
XP_011539563 (OMIM: 601176,608446) PREDICTED: glut ( 186) 1205 274.2 1.2e-73
XP_016856546 (OMIM: 601176,608446) PREDICTED: glut ( 253) 1016 232.7 5.4e-61
>>NP_002052 (OMIM: 601176,608446) glutamate--cysteine li (274 aa)
initn: 1802 init1: 1802 opt: 1802 Z-score: 2150.7 bits: 405.7 E(85289): 4.7e-113
Smith-Waterman score: 1802; 100.0% identity (100.0% similar) in 274 aa overlap (1-274:1-274)
10 20 30 40 50 60
pF1KE6 MGTDSRAAKALLARARTLHLQTGNLLNWGRLRKKCPSTHSEELHDCIQKTLNEWSSQINP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 MGTDSRAAKALLARARTLHLQTGNLLNWGRLRKKCPSTHSEELHDCIQKTLNEWSSQINP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 DLVREFPDVLECTVSHAVEKINPDEREEMKVSAKLFIVESNSSSSTRSAVDMACSVLGVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 DLVREFPDVLECTVSHAVEKINPDEREEMKVSAKLFIVESNSSSSTRSAVDMACSVLGVA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 QLDSVIIASPPIEDGVNLSLEHLQPYWEELENLVQSKKIVAIGTSDLDKTQLEQLYQWAQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 QLDSVIIASPPIEDGVNLSLEHLQPYWEELENLVQSKKIVAIGTSDLDKTQLEQLYQWAQ
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE6 VKPNSNQVNLASCCVMPPDLTAFAKQFDIQLLTHNDPKELLSEASFQEALQESIPDIQAH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 VKPNSNQVNLASCCVMPPDLTAFAKQFDIQLLTHNDPKELLSEASFQEALQESIPDIQAH
190 200 210 220 230 240
250 260 270
pF1KE6 EWVPLWLLRYSVIVKSRGIIKSKGYILQAKRRGS
::::::::::::::::::::::::::::::::::
NP_002 EWVPLWLLRYSVIVKSRGIIKSKGYILQAKRRGS
250 260 270
>>XP_016856545 (OMIM: 601176,608446) PREDICTED: glutamat (275 aa)
initn: 1466 init1: 1447 opt: 1450 Z-score: 1731.8 bits: 328.2 E(85289): 1e-89
Smith-Waterman score: 1450; 83.8% identity (90.8% similar) in 271 aa overlap (1-271:1-266)
10 20 30 40 50 60
pF1KE6 MGTDSRAAKALLARARTLHLQTGNLLNWGRLRKKCPSTHSEELHDCIQKTLNEWSSQINP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MGTDSRAAKALLARARTLHLQTGNLLNWGRLRKKCPSTHSEELHDCIQKTLNEWSSQINP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 DLVREFPDVLECTVSHAVEKINPDEREEMKVSAKLFIVESNSSSSTRSAVDMACSVLGVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DLVREFPDVLECTVSHAVEKINPDEREEMKVSAKLFIVESNSSSSTRSAVDMACSVLGVA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 QLDSVIIASPPIEDGVNLSLEHLQPYWEELENLVQSKKIVAIGTSDLDKTQLEQLYQWAQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QLDSVIIASPPIEDGVNLSLEHLQPYWEELENLVQSKKIVAIGTSDLDKTQLEQLYQWAQ
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE6 VKPNSNQVNLASCCVMPPDLTAFAKQFDIQLLTHNDPKELLSEASFQEALQESIPDIQAH
::::::::::::::::::::::::::::::::::::::: ..:... : .. ...
XP_016 VKPNSNQVNLASCCVMPPDLTAFAKQFDIQLLTHNDPKE----TGFHHVTQAGLEFLDSS
190 200 210 220 230
250 260 270
pF1KE6 EWVPLWLLRYSVIVKSRGIIKSKGYILQAKRRGS
. : . . :. .:::..:. .
XP_016 N-SPTSASQGAGILGMSHCAWTKGYFIQGDKYLEKVAHVI
240 250 260 270
>>NP_001295182 (OMIM: 601176,608446) glutamate--cysteine (252 aa)
initn: 1632 init1: 1368 opt: 1368 Z-score: 1634.9 bits: 310.2 E(85289): 2.5e-84
Smith-Waterman score: 1592; 92.0% identity (92.0% similar) in 274 aa overlap (1-274:1-252)
10 20 30 40 50 60
pF1KE6 MGTDSRAAKALLARARTLHLQTGNLLNWGRLRKKCPSTHSEELHDCIQKTLNEWSSQINP
::::::::::::::::::::::::::::::::::::::::::
NP_001 MGTDSRAAKALLARARTLHLQTGNLLNWGRLRKKCPSTHSEE------------------
10 20 30 40
70 80 90 100 110 120
pF1KE6 DLVREFPDVLECTVSHAVEKINPDEREEMKVSAKLFIVESNSSSSTRSAVDMACSVLGVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ----EFPDVLECTVSHAVEKINPDEREEMKVSAKLFIVESNSSSSTRSAVDMACSVLGVA
50 60 70 80 90
130 140 150 160 170 180
pF1KE6 QLDSVIIASPPIEDGVNLSLEHLQPYWEELENLVQSKKIVAIGTSDLDKTQLEQLYQWAQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QLDSVIIASPPIEDGVNLSLEHLQPYWEELENLVQSKKIVAIGTSDLDKTQLEQLYQWAQ
100 110 120 130 140 150
190 200 210 220 230 240
pF1KE6 VKPNSNQVNLASCCVMPPDLTAFAKQFDIQLLTHNDPKELLSEASFQEALQESIPDIQAH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VKPNSNQVNLASCCVMPPDLTAFAKQFDIQLLTHNDPKELLSEASFQEALQESIPDIQAH
160 170 180 190 200 210
250 260 270
pF1KE6 EWVPLWLLRYSVIVKSRGIIKSKGYILQAKRRGS
::::::::::::::::::::::::::::::::::
NP_001 EWVPLWLLRYSVIVKSRGIIKSKGYILQAKRRGS
220 230 240 250
>>XP_011539563 (OMIM: 601176,608446) PREDICTED: glutamat (186 aa)
initn: 1205 init1: 1205 opt: 1205 Z-score: 1443.0 bits: 274.2 E(85289): 1.2e-73
Smith-Waterman score: 1205; 100.0% identity (100.0% similar) in 186 aa overlap (89-274:1-186)
60 70 80 90 100 110
pF1KE6 NPDLVREFPDVLECTVSHAVEKINPDEREEMKVSAKLFIVESNSSSSTRSAVDMACSVLG
::::::::::::::::::::::::::::::
XP_011 MKVSAKLFIVESNSSSSTRSAVDMACSVLG
10 20 30
120 130 140 150 160 170
pF1KE6 VAQLDSVIIASPPIEDGVNLSLEHLQPYWEELENLVQSKKIVAIGTSDLDKTQLEQLYQW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VAQLDSVIIASPPIEDGVNLSLEHLQPYWEELENLVQSKKIVAIGTSDLDKTQLEQLYQW
40 50 60 70 80 90
180 190 200 210 220 230
pF1KE6 AQVKPNSNQVNLASCCVMPPDLTAFAKQFDIQLLTHNDPKELLSEASFQEALQESIPDIQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AQVKPNSNQVNLASCCVMPPDLTAFAKQFDIQLLTHNDPKELLSEASFQEALQESIPDIQ
100 110 120 130 140 150
240 250 260 270
pF1KE6 AHEWVPLWLLRYSVIVKSRGIIKSKGYILQAKRRGS
::::::::::::::::::::::::::::::::::::
XP_011 AHEWVPLWLLRYSVIVKSRGIIKSKGYILQAKRRGS
160 170 180
>>XP_016856546 (OMIM: 601176,608446) PREDICTED: glutamat (253 aa)
initn: 1296 init1: 1013 opt: 1016 Z-score: 1216.0 bits: 232.7 E(85289): 5.4e-61
Smith-Waterman score: 1240; 75.6% identity (82.7% similar) in 271 aa overlap (1-271:1-244)
10 20 30 40 50 60
pF1KE6 MGTDSRAAKALLARARTLHLQTGNLLNWGRLRKKCPSTHSEELHDCIQKTLNEWSSQINP
::::::::::::::::::::::::::::::::::::::::::
XP_016 MGTDSRAAKALLARARTLHLQTGNLLNWGRLRKKCPSTHSEE------------------
10 20 30 40
70 80 90 100 110 120
pF1KE6 DLVREFPDVLECTVSHAVEKINPDEREEMKVSAKLFIVESNSSSSTRSAVDMACSVLGVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ----EFPDVLECTVSHAVEKINPDEREEMKVSAKLFIVESNSSSSTRSAVDMACSVLGVA
50 60 70 80 90
130 140 150 160 170 180
pF1KE6 QLDSVIIASPPIEDGVNLSLEHLQPYWEELENLVQSKKIVAIGTSDLDKTQLEQLYQWAQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QLDSVIIASPPIEDGVNLSLEHLQPYWEELENLVQSKKIVAIGTSDLDKTQLEQLYQWAQ
100 110 120 130 140 150
190 200 210 220 230 240
pF1KE6 VKPNSNQVNLASCCVMPPDLTAFAKQFDIQLLTHNDPKELLSEASFQEALQESIPDIQAH
::::::::::::::::::::::::::::::::::::::: ..:... : .. ...
XP_016 VKPNSNQVNLASCCVMPPDLTAFAKQFDIQLLTHNDPKE----TGFHHVTQAGLEFLDSS
160 170 180 190 200 210
250 260 270
pF1KE6 EWVPLWLLRYSVIVKSRGIIKSKGYILQAKRRGS
. : . . :. .:::..:. .
XP_016 N-SPTSASQGAGILGMSHCAWTKGYFIQGDKYLEKVAHVI
220 230 240 250
274 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Nov 8 15:12:15 2016 done: Tue Nov 8 15:12:16 2016
Total Scan time: 4.680 Total Display time: 0.000
Function used was FASTA [36.3.4 Apr, 2011]