Result of FASTA (omim) for
pFN21AE6647
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE6647, 232 aa
1>>>pF1KE6647 232 - 232 aa - 232 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.6747+/-0.00037; mu= 12.1984+/- 0.023
mean_var=80.1884+/-15.482, 0's: 0 Z-trim(114.9): 129 B-trim: 105 in 1/50
Lambda= 0.143225
statistics sampled from 24904 (25043) to 24904 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.667), E-opt: 0.2 (0.294), width: 16
Scan time: 5.340
The best scores are: opt bits E(85289)
NP_066303 (OMIM: 235400,603075,605336) complement ( 330) 1484 316.1 4.4e-86
NP_000177 (OMIM: 126700,134370,235400,609814,61069 (1231) 1192 256.2 1.9e-67
NP_001160096 (OMIM: 235400,603075,605336) compleme ( 269) 1177 252.7 4.7e-67
XP_016856597 (OMIM: 126700,134370,235400,609814,61 ( 446) 891 193.7 4.3e-49
NP_001014975 (OMIM: 126700,134370,235400,609814,61 ( 449) 891 193.7 4.4e-49
NP_001188480 (OMIM: 605337) complement factor H-re ( 577) 770 168.8 1.8e-41
XP_016855602 (OMIM: 605337) PREDICTED: complement ( 458) 758 166.2 8.3e-41
XP_016855601 (OMIM: 605337) PREDICTED: complement ( 468) 758 166.2 8.5e-41
XP_016855599 (OMIM: 605337) PREDICTED: complement ( 519) 758 166.3 9.2e-41
XP_016855600 (OMIM: 605337) PREDICTED: complement ( 519) 758 166.3 9.2e-41
NP_001188479 (OMIM: 605337) complement factor H-re ( 578) 758 166.3 1e-40
NP_006675 (OMIM: 605337) complement factor H-relat ( 331) 753 165.1 1.3e-40
XP_016855603 (OMIM: 605337) PREDICTED: complement ( 387) 639 141.6 1.8e-33
XP_006711192 (OMIM: 605337) PREDICTED: complement ( 570) 639 141.7 2.5e-33
NP_005657 (OMIM: 600889) complement factor H-relat ( 270) 571 127.4 2.3e-29
XP_011507760 (OMIM: 600889) PREDICTED: complement ( 266) 557 124.5 1.7e-28
NP_002104 (OMIM: 134371,235400,603075) complement ( 330) 550 123.2 5.5e-28
XP_011507761 (OMIM: 600889) PREDICTED: complement ( 250) 531 119.2 6.7e-27
NP_110414 (OMIM: 608593,614809) complement factor ( 569) 519 116.9 7.3e-26
XP_011508322 (OMIM: 608593,614809) PREDICTED: comp ( 572) 465 105.7 1.7e-22
NP_001985 (OMIM: 134580,613235) coagulation factor ( 661) 417 95.9 1.8e-19
XP_011507586 (OMIM: 134580,613235) PREDICTED: coag ( 675) 417 95.9 1.9e-19
XP_011507585 (OMIM: 134580,613235) PREDICTED: coag ( 676) 417 95.9 1.9e-19
XP_016856598 (OMIM: 600889) PREDICTED: complement ( 211) 389 89.8 4e-18
XP_005245170 (OMIM: 600889) PREDICTED: complement ( 205) 300 71.4 1.3e-12
XP_011507762 (OMIM: 600889) PREDICTED: complement ( 201) 286 68.5 9.7e-12
XP_011507759 (OMIM: 134371,235400,603075) PREDICTE ( 265) 273 65.9 7.9e-11
XP_011507588 (OMIM: 134580,613235) PREDICTED: coag ( 628) 260 63.4 1e-09
NP_000564 (OMIM: 120620,607486,611162) complement (2039) 229 57.3 2.3e-07
XP_006711229 (OMIM: 120620,607486,611162) PREDICTE (2459) 229 57.4 2.6e-07
NP_000642 (OMIM: 120620,607486,611162) complement (2489) 229 57.4 2.6e-07
XP_011507507 (OMIM: 120620,607486,611162) PREDICTE (2554) 229 57.4 2.7e-07
XP_011507508 (OMIM: 120650,240500,610927,614699) P ( 969) 187 48.4 5e-05
NP_001006659 (OMIM: 120650,240500,610927,614699) c (1092) 187 48.5 5.6e-05
NP_001868 (OMIM: 120650,240500,610927,614699) comp (1033) 175 46.0 0.0003
NP_001171706 (OMIM: 607021) seizure 6-like protein ( 948) 174 45.7 0.00032
NP_000706 (OMIM: 120830) C4b-binding protein alpha ( 597) 170 44.8 0.00039
XP_005273308 (OMIM: 120830) PREDICTED: C4b-binding ( 597) 170 44.8 0.00039
XP_005273309 (OMIM: 120830) PREDICTED: C4b-binding ( 597) 170 44.8 0.00039
XP_005255309 (OMIM: 616667) PREDICTED: seizure 6-l ( 859) 171 45.1 0.00045
XP_011528341 (OMIM: 607021) PREDICTED: seizure 6-l ( 957) 171 45.1 0.00049
XP_011528340 (OMIM: 607021) PREDICTED: seizure 6-l ( 958) 171 45.1 0.00049
XP_011528339 (OMIM: 607021) PREDICTED: seizure 6-l ( 959) 171 45.1 0.00049
NP_001171704 (OMIM: 607021) seizure 6-like protein (1011) 171 45.1 0.00052
XP_005261496 (OMIM: 607021) PREDICTED: seizure 6-l (1012) 171 45.1 0.00052
NP_001171703 (OMIM: 607021) seizure 6-like protein (1013) 171 45.1 0.00052
XP_006724258 (OMIM: 607021) PREDICTED: seizure 6-l (1022) 171 45.1 0.00052
NP_001171702 (OMIM: 607021) seizure 6-like protein (1023) 171 45.1 0.00052
NP_066938 (OMIM: 607021) seizure 6-like protein is (1024) 171 45.1 0.00052
XP_016878624 (OMIM: 616667) PREDICTED: seizure 6-l ( 739) 169 44.6 0.00053
>>NP_066303 (OMIM: 235400,603075,605336) complement fact (330 aa)
initn: 1660 init1: 1484 opt: 1484 Z-score: 1666.4 bits: 316.1 E(85289): 4.4e-86
Smith-Waterman score: 1484; 99.0% identity (100.0% similar) in 206 aa overlap (1-206:1-206)
10 20 30 40 50 60
pF1KE6 MLLLINVILTLWVSCANGQVKPCDFPDIKHGGLFHENMRRPYFPVAVGKYYSYYCDEHFE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_066 MLLLINVILTLWVSCANGQVKPCDFPDIKHGGLFHENMRRPYFPVAVGKYYSYYCDEHFE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 TPSGSYWDYIHCTQNGWSPAVPCLRKCYFPYLENGYNQNYGRKFVQGNSTEVACHPGYGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_066 TPSGSYWDYIHCTQNGWSPAVPCLRKCYFPYLENGYNQNYGRKFVQGNSTEVACHPGYGL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 PKAQTTVTCTEKGWSPTPRCIRVRTCSKSDIEIENGFISESSSIYILNKEIQYKCKPGYA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_066 PKAQTTVTCTEKGWSPTPRCIRVRTCSKSDIEIENGFISESSSIYILNKEIQYKCKPGYA
130 140 150 160 170 180
190 200 210 220 230
pF1KE6 TADGNSSGSITCLQNGWSAQPICITACIAFRAHAQKSCTCRGRNECLILNFC
::::::::::::::::::::::::..
NP_066 TADGNSSGSITCLQNGWSAQPICINSSEKCGPPPPISNGDTTSFLLKVYVPQSRVEYQCQ
190 200 210 220 230 240
>>NP_000177 (OMIM: 126700,134370,235400,609814,610698) c (1231 aa)
initn: 1352 init1: 1179 opt: 1192 Z-score: 1332.0 bits: 256.2 E(85289): 1.9e-67
Smith-Waterman score: 1192; 78.3% identity (91.4% similar) in 198 aa overlap (10-207:312-509)
10 20 30
pF1KE6 MLLLINVILTLWVSCANGQVKPCDFPDIKHGGLFHENMR
: :. .::::.::::::::.:::::
NP_000 IKHRTGDEITYQCRNGFYPATRGNTAKCTSTGWIPAPRCTLKPCDYPDIKHGGLYHENMR
290 300 310 320 330 340
40 50 60 70 80 90
pF1KE6 RPYFPVAVGKYYSYYCDEHFETPSGSYWDYIHCTQNGWSPAVPCLRKCYFPYLENGYNQN
:::::::::::::::::::::::::::::.:::::.::::::::::::::::::::::::
NP_000 RPYFPVAVGKYYSYYCDEHFETPSGSYWDHIHCTQDGWSPAVPCLRKCYFPYLENGYNQN
350 360 370 380 390 400
100 110 120 130 140 150
pF1KE6 YGRKFVQGNSTEVACHPGYGLPKAQTTVTCTEKGWSPTPRCIRVRTCSKSDIEIENGFIS
.:::::::.: .:::::::.:::::::::: :.:::::::::::.:::::.:.:::::::
NP_000 HGRKFVQGKSIDVACHPGYALPKAQTTVTCMENGWSPTPRCIRVKTCSKSSIDIENGFIS
410 420 430 440 450 460
160 170 180 190 200 210
pF1KE6 ESSSIYILNKEIQYKCKPGYATADGNSSGSITCLQNGWSAQPICITACIAFRAHAQKSCT
::. : :... .:.:: ::.::::..:::::: ..:::::: :: .:
NP_000 ESQYTYALKEKAKYQCKLGYVTADGETSGSITCGKDGWSAQPTCIKSCDIPVFMNARTKN
470 480 490 500 510 520
220 230
pF1KE6 CRGRNECLILNFC
NP_000 DFTWFKLNDTLDYECHDGYESNTGSTTGSIVCGYNGWSDLPICYERECELPKIDVHLVPD
530 540 550 560 570 580
>--
initn: 142 init1: 77 opt: 193 Z-score: 216.4 bits: 49.7 E(85289): 2.6e-05
Smith-Waterman score: 233; 29.2% identity (60.2% similar) in 161 aa overlap (53-203:112-262)
30 40 50 60 70 80
pF1KE6 CDFPDIKHGGLFHENMRRPYFPVAVGKYYSYYCDEHFETPSGSYWDYIHCTQNGWSPAVP
: :.: .. : .: .: .::. .:
NP_000 KRPCGHPGDTPFGTFTLTGGNVFEYGVKAVYTCNEGYQL-LGEI-NYRECDTDGWTNDIP
90 100 110 120 130
90 100 110 120 130
pF1KE6 -C-LRKCYFPYL--ENGY----NQNYGRKFVQGNSTEVACHPGYGLPKAQTTVTCTEKG-
: . :: .: ::: .. :.. :.... .:. :: . ... . :.. :
NP_000 ICEVVKC-LPVTAPENGKIVSSAMEPDREYHFGQAVRFVCNSGYKI-EGDEEMHCSDDGF
140 150 160 170 180 190
140 150 160 170 180 190
pF1KE6 WSPT-PRCIRVRTCSKSDIEIENGFISESSSIYILNKEIQYKCKPGYATADGNSSGSITC
:: :.:... .:.. :. :... ::.. :: :...::::. :: .. :. .:
NP_000 WSKEKPKCVEI-SCKSPDV-INGSPISQKI-IYKENERFQYKCNMGYEYSE---RGDAVC
200 210 220 230 240 250
200 210 220 230
pF1KE6 LQNGWSAQPICITACIAFRAHAQKSCTCRGRNECLILNFC
..:: : :
NP_000 TESGWRPLPSCEEKSCDNPYIPNGDYSPLRIKHRTGDEITYQCRNGFYPATRGNTAKCTS
260 270 280 290 300 310
>>NP_001160096 (OMIM: 235400,603075,605336) complement f (269 aa)
initn: 1211 init1: 1104 opt: 1177 Z-score: 1324.9 bits: 252.7 E(85289): 4.7e-67
Smith-Waterman score: 1177; 72.5% identity (83.4% similar) in 229 aa overlap (1-225:1-226)
10 20 30 40 50 60
pF1KE6 MLLLINVILTLWVSCANGQVKPCDFPDIKHGGLFHENMRRPYFPVAVGKYYSYYCDEHFE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MLLLINVILTLWVSCANGQVKPCDFPDIKHGGLFHENMRRPYFPVAVGKYYSYYCDEHFE
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 TPSGSYWDYIHCTQNGWSPAVPCLRKCYFPYLENGYNQNYGRKFVQGNSTEVACHPGYGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TPSGSYWDYIHCTQNGWSPAVPCLRKCYFPYLENGYNQNYGRKFVQGNSTEVACHPGYGL
70 80 90 100 110 120
130 140 150 160 170
pF1KE6 PKAQTTVTCTEKGWSPTPRCIRVRTCSKSDIE--IENG-FISESSSIYILNKEIQYKCKP
::::::::::::::::::::::: . : : :: : ..:. .....:.:.:
NP_001 PKAQTTVTCTEKGWSPTPRCIRVNSSEKCGPPPPISNGDTTSFLLKVYVPQSRVEYQCQP
130 140 150 160 170 180
180 190 200 210 220 230
pF1KE6 GYATADGNSSGSITCLQNGWSAQPICITACIAFRAHAQKSCT-CRGRNECLILNFC
: . ..:. .:: .. :: : :: :: . . .:. .::..
NP_001 YY---ELQGSNYVTCSNGEWSEPPRCIHPCIITEENMNKNNIKLKGRSDRKYYAKTGDTI
190 200 210 220 230
NP_001 EFMCKLGYNANTSILSFQAVCREGIVEYPRCE
240 250 260
>>XP_016856597 (OMIM: 126700,134370,235400,609814,610698 (446 aa)
initn: 879 init1: 879 opt: 891 Z-score: 1002.3 bits: 193.7 E(85289): 4.3e-49
Smith-Waterman score: 891; 85.1% identity (93.3% similar) in 134 aa overlap (10-143:312-445)
10 20 30
pF1KE6 MLLLINVILTLWVSCANGQVKPCDFPDIKHGGLFHENMR
: :. .::::.::::::::.:::::
XP_016 IKHRTGDEITYQCRNGFYPATRGNTAKCTSTGWIPAPRCTLKPCDYPDIKHGGLYHENMR
290 300 310 320 330 340
40 50 60 70 80 90
pF1KE6 RPYFPVAVGKYYSYYCDEHFETPSGSYWDYIHCTQNGWSPAVPCLRKCYFPYLENGYNQN
:::::::::::::::::::::::::::::.:::::.::::::::::::::::::::::::
XP_016 RPYFPVAVGKYYSYYCDEHFETPSGSYWDHIHCTQDGWSPAVPCLRKCYFPYLENGYNQN
350 360 370 380 390 400
100 110 120 130 140 150
pF1KE6 YGRKFVQGNSTEVACHPGYGLPKAQTTVTCTEKGWSPTPRCIRVRTCSKSDIEIENGFIS
.:::::::.: .:::::::.:::::::::: :.:::::::::::
XP_016 HGRKFVQGKSIDVACHPGYALPKAQTTVTCMENGWSPTPRCIRVN
410 420 430 440
160 170 180 190 200 210
pF1KE6 ESSSIYILNKEIQYKCKPGYATADGNSSGSITCLQNGWSAQPICITACIAFRAHAQKSCT
>--
initn: 142 init1: 77 opt: 193 Z-score: 222.8 bits: 49.5 E(85289): 1.1e-05
Smith-Waterman score: 233; 29.2% identity (60.2% similar) in 161 aa overlap (53-203:112-262)
30 40 50 60 70 80
pF1KE6 CDFPDIKHGGLFHENMRRPYFPVAVGKYYSYYCDEHFETPSGSYWDYIHCTQNGWSPAVP
: :.: .. : .: .: .::. .:
XP_016 KRPCGHPGDTPFGTFTLTGGNVFEYGVKAVYTCNEGYQL-LGEI-NYRECDTDGWTNDIP
90 100 110 120 130
90 100 110 120 130
pF1KE6 -C-LRKCYFPYL--ENGY----NQNYGRKFVQGNSTEVACHPGYGLPKAQTTVTCTEKG-
: . :: .: ::: .. :.. :.... .:. :: . ... . :.. :
XP_016 ICEVVKC-LPVTAPENGKIVSSAMEPDREYHFGQAVRFVCNSGYKI-EGDEEMHCSDDGF
140 150 160 170 180 190
140 150 160 170 180 190
pF1KE6 WSPT-PRCIRVRTCSKSDIEIENGFISESSSIYILNKEIQYKCKPGYATADGNSSGSITC
:: :.:... .:.. :. :... ::.. :: :...::::. :: .. :. .:
XP_016 WSKEKPKCVEI-SCKSPDV-INGSPISQKI-IYKENERFQYKCNMGYEYSE---RGDAVC
200 210 220 230 240 250
200 210 220 230
pF1KE6 LQNGWSAQPICITACIAFRAHAQKSCTCRGRNECLILNFC
..:: : :
XP_016 TESGWRPLPSCEEKSCDNPYIPNGDYSPLRIKHRTGDEITYQCRNGFYPATRGNTAKCTS
260 270 280 290 300 310
>>NP_001014975 (OMIM: 126700,134370,235400,609814,610698 (449 aa)
initn: 879 init1: 879 opt: 891 Z-score: 1002.2 bits: 193.7 E(85289): 4.4e-49
Smith-Waterman score: 891; 85.1% identity (93.3% similar) in 134 aa overlap (10-143:312-445)
10 20 30
pF1KE6 MLLLINVILTLWVSCANGQVKPCDFPDIKHGGLFHENMR
: :. .::::.::::::::.:::::
NP_001 IKHRTGDEITYQCRNGFYPATRGNTAKCTSTGWIPAPRCTLKPCDYPDIKHGGLYHENMR
290 300 310 320 330 340
40 50 60 70 80 90
pF1KE6 RPYFPVAVGKYYSYYCDEHFETPSGSYWDYIHCTQNGWSPAVPCLRKCYFPYLENGYNQN
:::::::::::::::::::::::::::::.:::::.::::::::::::::::::::::::
NP_001 RPYFPVAVGKYYSYYCDEHFETPSGSYWDHIHCTQDGWSPAVPCLRKCYFPYLENGYNQN
350 360 370 380 390 400
100 110 120 130 140 150
pF1KE6 YGRKFVQGNSTEVACHPGYGLPKAQTTVTCTEKGWSPTPRCIRVRTCSKSDIEIENGFIS
.:::::::.: .:::::::.:::::::::: :.:::::::::::
NP_001 HGRKFVQGKSIDVACHPGYALPKAQTTVTCMENGWSPTPRCIRVSFTL
410 420 430 440
160 170 180 190 200 210
pF1KE6 ESSSIYILNKEIQYKCKPGYATADGNSSGSITCLQNGWSAQPICITACIAFRAHAQKSCT
>--
initn: 142 init1: 77 opt: 193 Z-score: 222.8 bits: 49.5 E(85289): 1.1e-05
Smith-Waterman score: 233; 29.2% identity (60.2% similar) in 161 aa overlap (53-203:112-262)
30 40 50 60 70 80
pF1KE6 CDFPDIKHGGLFHENMRRPYFPVAVGKYYSYYCDEHFETPSGSYWDYIHCTQNGWSPAVP
: :.: .. : .: .: .::. .:
NP_001 KRPCGHPGDTPFGTFTLTGGNVFEYGVKAVYTCNEGYQL-LGEI-NYRECDTDGWTNDIP
90 100 110 120 130
90 100 110 120 130
pF1KE6 -C-LRKCYFPYL--ENGY----NQNYGRKFVQGNSTEVACHPGYGLPKAQTTVTCTEKG-
: . :: .: ::: .. :.. :.... .:. :: . ... . :.. :
NP_001 ICEVVKC-LPVTAPENGKIVSSAMEPDREYHFGQAVRFVCNSGYKI-EGDEEMHCSDDGF
140 150 160 170 180 190
140 150 160 170 180 190
pF1KE6 WSPT-PRCIRVRTCSKSDIEIENGFISESSSIYILNKEIQYKCKPGYATADGNSSGSITC
:: :.:... .:.. :. :... ::.. :: :...::::. :: .. :. .:
NP_001 WSKEKPKCVEI-SCKSPDV-INGSPISQKI-IYKENERFQYKCNMGYEYSE---RGDAVC
200 210 220 230 240 250
200 210 220 230
pF1KE6 LQNGWSAQPICITACIAFRAHAQKSCTCRGRNECLILNFC
..:: : :
NP_001 TESGWRPLPSCEEKSCDNPYIPNGDYSPLRIKHRTGDEITYQCRNGFYPATRGNTAKCTS
260 270 280 290 300 310
>>NP_001188480 (OMIM: 605337) complement factor H-relate (577 aa)
initn: 1131 init1: 603 opt: 770 Z-score: 865.5 bits: 168.8 E(85289): 1.8e-41
Smith-Waterman score: 793; 59.4% identity (68.6% similar) in 207 aa overlap (1-207:1-148)
10 20 30 40 50 60
pF1KE6 MLLLINVILTLWVSCANGQVKPCDFPDIKHGGLFHENMRRPYFPVAVGKYYSYYCDEHFE
::::::::::::::::::::::::::.:.::::.....:: :::.:.:. ::::::..:
NP_001 MLLLINVILTLWVSCANGQVKPCDFPEIQHGGLYYKSLRRLYFPAAAGQSYSYYCDQNFV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 TPSGSYWDYIHCTQNGWSPAVPCLRKCYFPYLENGYNQNYGRKFVQGNSTEVACHPGYGL
::::::::::::::.::::.:::::
NP_001 TPSGSYWDYIHCTQDGWSPTVPCLR-----------------------------------
70 80
130 140 150 160 170 180
pF1KE6 PKAQTTVTCTEKGWSPTPRCIRVRTCSKSDIEIENGFISESSSIYILNKEIQYKCKPGYA
::::::.:::::::::::::::::.: ::.::::::
NP_001 ------------------------TCSKSDVEIENGFISESSSIYILNEETQYNCKPGYA
90 100 110 120
190 200 210 220 230
pF1KE6 TADGNSSGSITCLQNGWSAQPICITACIAFRAHAQKSCTCRGRNECLILNFC
::.:::::::::::::::.::::: :
NP_001 TAEGNSSGSITCLQNGWSTQPICIKFCDMPVFENSRAKSNGMWFKLHDTLDYECYDGYES
130 140 150 160 170 180
>--
initn: 585 init1: 466 opt: 649 Z-score: 730.4 bits: 143.8 E(85289): 6.1e-34
Smith-Waterman score: 706; 55.6% identity (63.4% similar) in 205 aa overlap (12-207:250-395)
10 20 30
pF1KE6 MLLLINVILTLWVSCANGQ---------VKPCDFPDIKHGG
.:.:.::. .:::.::.:.::
NP_001 DTTSFPQKVYLPWSRVEYQCQSYYELQGSKYVTCSNGDWSEPPRCISMKPCEFPEIQHGH
220 230 240 250 260 270
40 50 60 70 80 90
pF1KE6 LFHENMRRPYFPVAVGKYYSYYCDEHFETPSGSYWDYIHCTQNGWSPAVPCLRKCYFPYL
:..:: ::::::::.:. ::::::..: ::::::::::::::.:: :.:::::
NP_001 LYYENTRRPYFPVATGQSYSYYCDQNFVTPSGSYWDYIHCTQDGWLPTVPCLR-------
280 290 300 310 320 330
100 110 120 130 140 150
pF1KE6 ENGYNQNYGRKFVQGNSTEVACHPGYGLPKAQTTVTCTEKGWSPTPRCIRVRTCSKSDIE
::::::::
NP_001 ----------------------------------------------------TCSKSDIE
340
160 170 180 190 200 210
pF1KE6 IENGFISESSSIYILNKEIQYKCKPGYATADGNSSGSITCLQNGWSAQPICITACIAFRA
:::::::::::::::::::::::::::::::::::::::::::::::::::: :
NP_001 IENGFISESSSIYILNKEIQYKCKPGYATADGNSSGSITCLQNGWSAQPICIKFCDMPVF
350 360 370 380 390 400
220 230
pF1KE6 HAQKSCTCRGRNECLILNFC
NP_001 ENSRAKSNGMRFKLHDTLDYECYDGYEISYGNTTGSIVCGEDGWSHFPTCYNSSEKCGPP
410 420 430 440 450 460
>>XP_016855602 (OMIM: 605337) PREDICTED: complement fact (458 aa)
initn: 1119 init1: 481 opt: 758 Z-score: 853.6 bits: 166.2 E(85289): 8.3e-41
Smith-Waterman score: 781; 59.1% identity (68.3% similar) in 208 aa overlap (1-207:1-149)
10 20 30 40 50
pF1KE6 MLLLINVILTLWVSCANGQ-VKPCDFPDIKHGGLFHENMRRPYFPVAVGKYYSYYCDEHF
::::::::::::::::::: :::::::.:.::::.....:: :::.:.:. ::::::..:
XP_016 MLLLINVILTLWVSCANGQEVKPCDFPEIQHGGLYYKSLRRLYFPAAAGQSYSYYCDQNF
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE6 ETPSGSYWDYIHCTQNGWSPAVPCLRKCYFPYLENGYNQNYGRKFVQGNSTEVACHPGYG
::::::::::::::.::::.:::::
XP_016 VTPSGSYWDYIHCTQDGWSPTVPCLR----------------------------------
70 80
120 130 140 150 160 170
pF1KE6 LPKAQTTVTCTEKGWSPTPRCIRVRTCSKSDIEIENGFISESSSIYILNKEIQYKCKPGY
::::::.:::::::::::::::::.: ::.:::::
XP_016 -------------------------TCSKSDVEIENGFISESSSIYILNEETQYNCKPGY
90 100 110 120
180 190 200 210 220 230
pF1KE6 ATADGNSSGSITCLQNGWSAQPICITACIAFRAHAQKSCTCRGRNECLILNFC
:::.:::::::::::::::.::::: :
XP_016 ATAEGNSSGSITCLQNGWSTQPICIKFCDMPVFENSRAKSNGMWFKLHDTLDYECYDGYE
130 140 150 160 170 180
>--
initn: 585 init1: 466 opt: 650 Z-score: 733.0 bits: 143.9 E(85289): 4.3e-34
Smith-Waterman score: 706; 55.6% identity (63.4% similar) in 205 aa overlap (12-207:251-396)
10 20 30
pF1KE6 MLLLINVILTLWVSCANGQ---------VKPCDFPDIKHGG
.:.:.::. .:::.::.:.::
XP_016 DTTSFPQKVYLPWSRVEYQCQSYYELQGSKYVTCSNGDWSEPPRCISMKPCEFPEIQHGH
230 240 250 260 270 280
40 50 60 70 80 90
pF1KE6 LFHENMRRPYFPVAVGKYYSYYCDEHFETPSGSYWDYIHCTQNGWSPAVPCLRKCYFPYL
:..:: ::::::::.:. ::::::..: ::::::::::::::.:: :.:::::
XP_016 LYYENTRRPYFPVATGQSYSYYCDQNFVTPSGSYWDYIHCTQDGWLPTVPCLR-------
290 300 310 320 330
100 110 120 130 140 150
pF1KE6 ENGYNQNYGRKFVQGNSTEVACHPGYGLPKAQTTVTCTEKGWSPTPRCIRVRTCSKSDIE
::::::::
XP_016 ----------------------------------------------------TCSKSDIE
340
160 170 180 190 200 210
pF1KE6 IENGFISESSSIYILNKEIQYKCKPGYATADGNSSGSITCLQNGWSAQPICITACIAFRA
:::::::::::::::::::::::::::::::::::::::::::::::::::: :
XP_016 IENGFISESSSIYILNKEIQYKCKPGYATADGNSSGSITCLQNGWSAQPICIKFCDMPVF
350 360 370 380 390 400
220 230
pF1KE6 HAQKSCTCRGRNECLILNFC
XP_016 ENSRAKSNGMRFKLHDTLDYECYDGYEISYGNTTGSIVCGEDGWSHFPTCYSIHFCR
410 420 430 440 450
>>XP_016855601 (OMIM: 605337) PREDICTED: complement fact (468 aa)
initn: 1119 init1: 481 opt: 758 Z-score: 853.4 bits: 166.2 E(85289): 8.5e-41
Smith-Waterman score: 781; 59.1% identity (68.3% similar) in 208 aa overlap (1-207:1-149)
10 20 30 40 50
pF1KE6 MLLLINVILTLWVSCANGQ-VKPCDFPDIKHGGLFHENMRRPYFPVAVGKYYSYYCDEHF
::::::::::::::::::: :::::::.:.::::.....:: :::.:.:. ::::::..:
XP_016 MLLLINVILTLWVSCANGQEVKPCDFPEIQHGGLYYKSLRRLYFPAAAGQSYSYYCDQNF
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE6 ETPSGSYWDYIHCTQNGWSPAVPCLRKCYFPYLENGYNQNYGRKFVQGNSTEVACHPGYG
::::::::::::::.::::.:::::
XP_016 VTPSGSYWDYIHCTQDGWSPTVPCLR----------------------------------
70 80
120 130 140 150 160 170
pF1KE6 LPKAQTTVTCTEKGWSPTPRCIRVRTCSKSDIEIENGFISESSSIYILNKEIQYKCKPGY
::::::.:::::::::::::::::.: ::.:::::
XP_016 -------------------------TCSKSDVEIENGFISESSSIYILNEETQYNCKPGY
90 100 110 120
180 190 200 210 220 230
pF1KE6 ATADGNSSGSITCLQNGWSAQPICITACIAFRAHAQKSCTCRGRNECLILNFC
:::.:::::::::::::::.::::: :
XP_016 ATAEGNSSGSITCLQNGWSTQPICIKFCDMPVFENSRAKSNGMWFKLHDTLDYECYDGYE
130 140 150 160 170 180
>--
initn: 585 init1: 466 opt: 650 Z-score: 732.8 bits: 143.9 E(85289): 4.4e-34
Smith-Waterman score: 706; 55.6% identity (63.4% similar) in 205 aa overlap (12-207:251-396)
10 20 30
pF1KE6 MLLLINVILTLWVSCANGQ---------VKPCDFPDIKHGG
.:.:.::. .:::.::.:.::
XP_016 DTTSFPQKVYLPWSRVEYQCQSYYELQGSKYVTCSNGDWSEPPRCISMKPCEFPEIQHGH
230 240 250 260 270 280
40 50 60 70 80 90
pF1KE6 LFHENMRRPYFPVAVGKYYSYYCDEHFETPSGSYWDYIHCTQNGWSPAVPCLRKCYFPYL
:..:: ::::::::.:. ::::::..: ::::::::::::::.:: :.:::::
XP_016 LYYENTRRPYFPVATGQSYSYYCDQNFVTPSGSYWDYIHCTQDGWLPTVPCLR-------
290 300 310 320 330
100 110 120 130 140 150
pF1KE6 ENGYNQNYGRKFVQGNSTEVACHPGYGLPKAQTTVTCTEKGWSPTPRCIRVRTCSKSDIE
::::::::
XP_016 ----------------------------------------------------TCSKSDIE
340
160 170 180 190 200 210
pF1KE6 IENGFISESSSIYILNKEIQYKCKPGYATADGNSSGSITCLQNGWSAQPICITACIAFRA
:::::::::::::::::::::::::::::::::::::::::::::::::::: :
XP_016 IENGFISESSSIYILNKEIQYKCKPGYATADGNSSGSITCLQNGWSAQPICIKFCDMPVF
350 360 370 380 390 400
220 230
pF1KE6 HAQKSCTCRGRNECLILNFC
XP_016 ENSRAKSNGMRFKLHDTLDYECYDGYEISYGNTTGSIVCGEDGWSHFPTCYIFFFRFFRK
410 420 430 440 450 460
>>XP_016855599 (OMIM: 605337) PREDICTED: complement fact (519 aa)
initn: 1182 init1: 481 opt: 758 Z-score: 852.8 bits: 166.3 E(85289): 9.2e-41
Smith-Waterman score: 781; 59.1% identity (68.3% similar) in 208 aa overlap (1-207:1-149)
10 20 30 40 50
pF1KE6 MLLLINVILTLWVSCANGQ-VKPCDFPDIKHGGLFHENMRRPYFPVAVGKYYSYYCDEHF
::::::::::::::::::: :::::::.:.::::.....:: :::.:.:. ::::::..:
XP_016 MLLLINVILTLWVSCANGQEVKPCDFPEIQHGGLYYKSLRRLYFPAAAGQSYSYYCDQNF
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE6 ETPSGSYWDYIHCTQNGWSPAVPCLRKCYFPYLENGYNQNYGRKFVQGNSTEVACHPGYG
::::::::::::::.::::.:::::
XP_016 VTPSGSYWDYIHCTQDGWSPTVPCLR----------------------------------
70 80
120 130 140 150 160 170
pF1KE6 LPKAQTTVTCTEKGWSPTPRCIRVRTCSKSDIEIENGFISESSSIYILNKEIQYKCKPGY
::::::.:::::::::::::::::.: ::.:::::
XP_016 -------------------------TCSKSDVEIENGFISESSSIYILNEETQYNCKPGY
90 100 110 120
180 190 200 210 220 230
pF1KE6 ATADGNSSGSITCLQNGWSAQPICITACIAFRAHAQKSCTCRGRNECLILNFC
:::.:::::::::::::::.::::: :
XP_016 ATAEGNSSGSITCLQNGWSTQPICIKFCDMPVFENSRAKSNGMWFKLHDTLDYECYDGYE
130 140 150 160 170 180
>--
initn: 892 init1: 420 opt: 619 Z-score: 697.6 bits: 137.5 E(85289): 4.1e-32
Smith-Waterman score: 698; 55.4% identity (64.2% similar) in 204 aa overlap (12-206:251-395)
10 20 30
pF1KE6 MLLLINVILTLWVSCANGQ---------VKPCDFPDIKHGG
.:.:.::. .:::.::.:.::
XP_016 DTTSFPQKVYLPWSRVEYQCQSYYELQGSKYVTCSNGDWSEPPRCISMKPCEFPEIQHGH
230 240 250 260 270 280
40 50 60 70 80 90
pF1KE6 LFHENMRRPYFPVAVGKYYSYYCDEHFETPSGSYWDYIHCTQNGWSPAVPCLRKCYFPYL
:..:: ::::::::.:. ::::::..: ::::::::::::::.:: :.:::::
XP_016 LYYENTRRPYFPVATGQSYSYYCDQNFVTPSGSYWDYIHCTQDGWLPTVPCLR-------
290 300 310 320 330
100 110 120 130 140 150
pF1KE6 ENGYNQNYGRKFVQGNSTEVACHPGYGLPKAQTTVTCTEKGWSPTPRCIRVRTCSKSDIE
::::::::
XP_016 ----------------------------------------------------TCSKSDIE
340
160 170 180 190 200 210
pF1KE6 IENGFISESSSIYILNKEIQYKCKPGYATADGNSSGSITCLQNGWSAQPICITACIAFRA
::::::::::::::::::::::::::::::::::::::::::::::::::::..
XP_016 IENGFISESSSIYILNKEIQYKCKPGYATADGNSSGSITCLQNGWSAQPICINSSEKCGP
350 360 370 380 390 400
220 230
pF1KE6 HAQKSCTCRGRNECLILNFC
XP_016 PPPISNGDTTSFLLKVYVPQSRVEYQCQSYYELQGSNYVTCSNGEWSEPPRCIHPCIITE
410 420 430 440 450 460
>>XP_016855600 (OMIM: 605337) PREDICTED: complement fact (519 aa)
initn: 1119 init1: 481 opt: 758 Z-score: 852.8 bits: 166.3 E(85289): 9.2e-41
Smith-Waterman score: 781; 59.1% identity (68.3% similar) in 208 aa overlap (1-207:1-149)
10 20 30 40 50
pF1KE6 MLLLINVILTLWVSCANGQ-VKPCDFPDIKHGGLFHENMRRPYFPVAVGKYYSYYCDEHF
::::::::::::::::::: :::::::.:.::::.....:: :::.:.:. ::::::..:
XP_016 MLLLINVILTLWVSCANGQEVKPCDFPEIQHGGLYYKSLRRLYFPAAAGQSYSYYCDQNF
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE6 ETPSGSYWDYIHCTQNGWSPAVPCLRKCYFPYLENGYNQNYGRKFVQGNSTEVACHPGYG
::::::::::::::.::::.:::::
XP_016 VTPSGSYWDYIHCTQDGWSPTVPCLR----------------------------------
70 80
120 130 140 150 160 170
pF1KE6 LPKAQTTVTCTEKGWSPTPRCIRVRTCSKSDIEIENGFISESSSIYILNKEIQYKCKPGY
::::::.:::::::::::::::::.: ::.:::::
XP_016 -------------------------TCSKSDVEIENGFISESSSIYILNEETQYNCKPGY
90 100 110 120
180 190 200 210 220 230
pF1KE6 ATADGNSSGSITCLQNGWSAQPICITACIAFRAHAQKSCTCRGRNECLILNFC
:::.:::::::::::::::.::::: :
XP_016 ATAEGNSSGSITCLQNGWSTQPICIKFCDMPVFENSRAKSNGMWFKLHDTLDYECYDGYE
130 140 150 160 170 180
>--
initn: 585 init1: 466 opt: 649 Z-score: 731.1 bits: 143.7 E(85289): 5.6e-34
Smith-Waterman score: 706; 55.6% identity (63.4% similar) in 205 aa overlap (12-207:251-396)
10 20 30
pF1KE6 MLLLINVILTLWVSCANGQ---------VKPCDFPDIKHGG
.:.:.::. .:::.::.:.::
XP_016 DTTSFPQKVYLPWSRVEYQCQSYYELQGSKYVTCSNGDWSEPPRCISMKPCEFPEIQHGH
230 240 250 260 270 280
40 50 60 70 80 90
pF1KE6 LFHENMRRPYFPVAVGKYYSYYCDEHFETPSGSYWDYIHCTQNGWSPAVPCLRKCYFPYL
:..:: ::::::::.:. ::::::..: ::::::::::::::.:: :.:::::
XP_016 LYYENTRRPYFPVATGQSYSYYCDQNFVTPSGSYWDYIHCTQDGWLPTVPCLR-------
290 300 310 320 330
100 110 120 130 140 150
pF1KE6 ENGYNQNYGRKFVQGNSTEVACHPGYGLPKAQTTVTCTEKGWSPTPRCIRVRTCSKSDIE
::::::::
XP_016 ----------------------------------------------------TCSKSDIE
340
160 170 180 190 200 210
pF1KE6 IENGFISESSSIYILNKEIQYKCKPGYATADGNSSGSITCLQNGWSAQPICITACIAFRA
:::::::::::::::::::::::::::::::::::::::::::::::::::: :
XP_016 IENGFISESSSIYILNKEIQYKCKPGYATADGNSSGSITCLQNGWSAQPICIKFCDMPVF
350 360 370 380 390 400
220 230
pF1KE6 HAQKSCTCRGRNECLILNFC
XP_016 ENSRAKSNGMRFKLHDTLDYECYDGYEISYGNTTGSIVCGEDGWSHFPTCYNSSEKCGPP
410 420 430 440 450 460
232 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Nov 8 15:05:36 2016 done: Tue Nov 8 15:05:37 2016
Total Scan time: 5.340 Total Display time: 0.000
Function used was FASTA [36.3.4 Apr, 2011]