FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KE6644, 242 aa
  1>>>pF1KE6644 242 - 242 aa - 242 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 5.7085+/-0.000299; mu= 14.3249+/- 0.019
 mean_var=91.8641+/-18.361, 0's: 0 Z-trim(118.9): 8  B-trim: 0 in 0/53
 Lambda= 0.133814
 statistics sampled from 32258 (32266) to 32258 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.752), E-opt: 0.2 (0.378), width:  16
 Scan time:  5.010

The best scores are:                                      opt bits E(85289)
NP_803431 (OMIM: 608847) ferritin, mitochondrial p ( 242) 1644 326.6 2.3e-89
NP_002023 (OMIM: 134770,615517) ferritin heavy cha ( 183)  981 198.5 6.4e-51
NP_114100 (OMIM: 300308) ferritin heavy polypeptid ( 183)  752 154.3 1.3e-37
NP_000137 (OMIM: 134790,600886,606159,615604) ferr ( 175)  654 135.4 6.3e-32


>>NP_803431 (OMIM: 608847) ferritin, mitochondrial precu  (242 aa)
 initn: 1644 init1: 1644 opt: 1644  Z-score: 1725.2  bits: 326.6 E(85289): 2.3e-89
Smith-Waterman score: 1644; 100.0% identity (100.0% similar) in 242 aa overlap (1-242:1-242)

               10        20        30        40        50        60
pF1KE6 MLSCFRLLSRHISPSLASLRPVRCCFALPLRWAPGRPLDPRQIAPRRPLAAAASSRDPTG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_803 MLSCFRLLSRHISPSLASLRPVRCCFALPLRWAPGRPLDPRQIAPRRPLAAAASSRDPTG
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE6 PAAGPSRVRQNFHPDSEAAINRQINLELYASYVYLSMAYYFSRDDVALNNFSRYFLHQSR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_803 PAAGPSRVRQNFHPDSEAAINRQINLELYASYVYLSMAYYFSRDDVALNNFSRYFLHQSR
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE6 EETEHAEKLMRLQNQRGGRIRLQDIKKPEQDDWESGLHAMECALLLEKNVNQSLLELHAL
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_803 EETEHAEKLMRLQNQRGGRIRLQDIKKPEQDDWESGLHAMECALLLEKNVNQSLLELHAL
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KE6 ASDKGDPHLCDFLETYYLNEQVKSIKELGDHVHNLVKMGAPDAGLAEYLFDTHTLGNENK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_803 ASDKGDPHLCDFLETYYLNEQVKSIKELGDHVHNLVKMGAPDAGLAEYLFDTHTLGNENK
              190       200       210       220       230       240

         
pF1KE6 QN
       ::
NP_803 QN
         

>>NP_002023 (OMIM: 134770,615517) ferritin heavy chain [  (183 aa)
 initn: 986 init1: 971 opt: 981  Z-score: 1035.1  bits: 198.5 E(85289): 6.4e-51
Smith-Waterman score: 981; 80.6% identity (93.9% similar) in 180 aa overlap (63-242:4-183)

             40        50        60        70        80        90  
pF1KE6 APGRPLDPRQIAPRRPLAAAASSRDPTGPAAGPSRVRQNFHPDSEAAINRQINLELYASY
                                     :. :.::::.: ::::::::::::::::::
NP_002                            MTTASTSQVRQNYHQDSEAAINRQINLELYASY
                                          10        20        30   

            100       110       120       130       140       150  
pF1KE6 VYLSMAYYFSRDDVALNNFSRYFLHQSREETEHAEKLMRLQNQRGGRIRLQDIKKPEQDD
       :::::.:::.::::::.::..::::::.:: :::::::.::::::::: :::::::. ::
NP_002 VYLSMSYYFDRDDVALKNFAKYFLHQSHEEREHAEKLMKLQNQRGGRIFLQDIKKPDCDD
            40        50        60        70        80        90   

            160       170       180       190       200       210  
pF1KE6 WESGLHAMECALLLEKNVNQSLLELHALASDKGDPHLCDFLETYYLNEQVKSIKELGDHV
       :::::.:::::: ::::::::::::: ::.::.:::::::.::.:::::::.::::::::
NP_002 WESGLNAMECALHLEKNVNQSLLELHKLATDKNDPHLCDFIETHYLNEQVKAIKELGDHV
           100       110       120       130       140       150   

            220       230       240  
pF1KE6 HNLVKMGAPDAGLAEYLFDTHTLGNENKQN
        :: :::::..:::::::: ::::. ....
NP_002 TNLRKMGAPESGLAEYLFDKHTLGDSDNES
           160       170       180   

>>NP_114100 (OMIM: 300308) ferritin heavy polypeptide-li  (183 aa)
 initn: 765 init1: 749 opt: 752  Z-score: 796.2  bits: 154.3 E(85289): 1.3e-37
Smith-Waterman score: 752; 65.4% identity (85.5% similar) in 179 aa overlap (63-241:4-182)

             40        50        60        70        80        90  
pF1KE6 APGRPLDPRQIAPRRPLAAAASSRDPTGPAAGPSRVRQNFHPDSEAAINRQINLELYASY
                                     : ::.:::..  . .:::: .:.::::.::
NP_114                            MATAQPSQVRQKYDTNCDAAINSHITLELYTSY
                                          10        20        30   

            100       110       120       130       140       150  
pF1KE6 VYLSMAYYFSRDDVALNNFSRYFLHQSREETEHAEKLMRLQNQRGGRIRLQDIKKPEQDD
       .:::::.::.::::::.:: ::::. : .. :::.::::::: :::.: :.::.::: . 
NP_114 LYLSMAFYFNRDDVALENFFRYFLRLSDDKMEHAQKLMRLQNLRGGHICLHDIRKPECQG
            40        50        60        70        80        90   

            160       170       180       190       200       210  
pF1KE6 WESGLHAMECALLLEKNVNQSLLELHALASDKGDPHLCDFLETYYLNEQVKSIKELGDHV
       ::::: ::: :. ::::::::::.:. :: .::::.:: :::..::.::::.::::: .:
NP_114 WESGLVAMESAFHLEKNVNQSLLDLYQLAVEKGDPQLCHFLESHYLHEQVKTIKELGGYV
           100       110       120       130       140       150   

            220       230       240  
pF1KE6 HNLVKMGAPDAGLAEYLFDTHTLGNENKQN
        :: :. .:.:::::::::  :::.. :. 
NP_114 SNLRKICSPEAGLAEYLFDKLTLGGRVKET
           160       170       180   

>>NP_000137 (OMIM: 134790,600886,606159,615604) ferritin  (175 aa)
 initn: 660 init1: 644 opt: 654  Z-score: 694.2  bits: 135.4 E(85289): 6.3e-32
Smith-Waterman score: 654; 54.3% identity (82.7% similar) in 173 aa overlap (66-238:3-175)

          40        50        60        70        80        90     
pF1KE6 RPLDPRQIAPRRPLAAAASSRDPTGPAAGPSRVRQNFHPDSEAAINRQINLELYASYVYL
                                     :..:::.  : :::.:  .:: : :::.::
NP_000                             MSSQIRQNYSTDVEAAVNSLVNLYLQASYTYL
                                           10        20        30  

         100       110       120       130       140       150     
pF1KE6 SMAYYFSRDDVALNNFSRYFLHQSREETEHAEKLMRLQNQRGGRIRLQDIKKPEQDDWES
       :...::.::::::.. :..: . ..:. :  :.:...:::::::  .:::::: .:.: .
NP_000 SLGFYFDRDDVALEGVSHFFRELAEEKREGYERLLKMQNQRGGRALFQDIKKPAEDEWGK
             40        50        60        70        80        90  

         160       170       180       190       200       210     
pF1KE6 GLHAMECALLLEKNVNQSLLELHALASDKGDPHLCDFLETYYLNEQVKSIKELGDHVHNL
          ::. :. :::..::.::.::::.: . ::::::::::..:.:.:: ::..:::. ::
NP_000 TPDAMKAAMALEKKLNQALLDLHALGSARTDPHLCDFLETHFLDEEVKLIKKMGDHLTNL
            100       110       120       130       140       150  

         220       230       240  
pF1KE6 VKMGAPDAGLAEYLFDTHTLGNENKQN
        ..:.:.:::.::::.  :: ..    
NP_000 HRLGGPEAGLGEYLFERLTLKHD    
            160       170         




242 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Tue Nov  8 15:03:55 2016 done: Tue Nov  8 15:03:56 2016
 Total Scan time:  5.010 Total Display time: -0.030

Function used was FASTA [36.3.4 Apr, 2011]