FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KE6641, 259 aa
  1>>>pF1KE6641 259 - 259 aa - 259 aa
Library: human.CCDS.faa
  18511270 residues in 32554 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 5.8790+/-0.000848; mu= 13.1339+/- 0.051
 mean_var=107.0708+/-20.967, 0's: 0 Z-trim(110.4): 30  B-trim: 69 in 2/51
 Lambda= 0.123948
 statistics sampled from 11543 (11558) to 11543 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.724), E-opt: 0.2 (0.355), width:  16
 Scan time:  1.510

The best scores are:                                      opt bits E(32554)
CCDS3675.1 DKK2 gene_id:27123|Hs108|chr4           ( 259) 1869 344.4 4.7e-95
CCDS7246.1 DKK1 gene_id:22943|Hs108|chr10          ( 266)  729 140.5 1.1e-33
CCDS6130.1 DKK4 gene_id:27121|Hs108|chr8           ( 224)  568 111.7 4.5e-25


>>CCDS3675.1 DKK2 gene_id:27123|Hs108|chr4                (259 aa)
 initn: 1869 init1: 1869 opt: 1869  Z-score: 1820.0  bits: 344.4 E(32554): 4.7e-95
Smith-Waterman score: 1869; 99.6% identity (100.0% similar) in 259 aa overlap (1-259:1-259)

               10        20        30        40        50        60
pF1KE6 MAALMRSKDSSCCLLLLAAVLMVESSQIGSSRAKLNSIKSSLGGETPGQAANRSAGMYQG
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS36 MAALMRSKDSSCCLLLLAAVLMVESSQIGSSRAKLNSIKSSLGGETPGQAANRSAGMYQG
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE6 LAFGGSKKGKNLGQAYPCSSDKECEVGRYCHSPHQGSSACMVCRRKKKRCHRDGMCCPST
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS36 LAFGGSKKGKNLGQAYPCSSDKECEVGRYCHSPHQGSSACMVCRRKKKRCHRDGMCCPST
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE6 RCNNGICIPVTESILTPHIPALDGTQHRDRNHGHYSNHDLGWQNLGRPHTKMSHIKGHEG
       :::::::::::::::::::::::::.::::::::::::::::::::::::::::::::::
CCDS36 RCNNGICIPVTESILTPHIPALDGTRHRDRNHGHYSNHDLGWQNLGRPHTKMSHIKGHEG
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KE6 DPCLRSSDCIEGFCCARHFWTKICKPVLHQGEVCTKQRKKGSHGLEIFQRCDCAKGLSCK
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS36 DPCLRSSDCIEGFCCARHFWTKICKPVLHQGEVCTKQRKKGSHGLEIFQRCDCAKGLSCK
              190       200       210       220       230       240

              250         
pF1KE6 VWKDATYSSKARLHVCQKI
       :::::::::::::::::::
CCDS36 VWKDATYSSKARLHVCQKI
              250         

>>CCDS7246.1 DKK1 gene_id:22943|Hs108|chr10               (266 aa)
 initn: 595 init1: 436 opt: 729  Z-score: 718.2  bits: 140.5 E(32554): 1.1e-33
Smith-Waterman score: 729; 42.9% identity (68.1% similar) in 273 aa overlap (1-258:1-265)

               10        20            30        40             50 
pF1KE6 MAALMRSKDSSCCLLLLAAVL----MVESSQIGSSRAKLNSIKS---SLGGET--PGQAA
       : ::  .  .   . ..::.:    ..  :   .:  . :.::.    ::: .  ::.:.
CCDS72 MMALGAAGATRVFVAMVAAALGGHPLLGVSATLNSVLNSNAIKNLPPPLGGAAGHPGSAV
               10        20        30        40        50        60

              60         70        80        90           100      
pF1KE6 NRSAGMYQGLAFGGSK-KGKNLGQAYPCSSDKECEVGRYCHSPHQGSSA----CMVCRRK
       . . :.   :  ::.: .  .  : :::. :.:: . .:: :: .:..:    :..::..
CCDS72 SAAPGI---LYPGGNKYQTIDNYQPYPCAEDEECGTDEYCASPTRGGDAGVQICLACRKR
                  70        80        90       100       110       

        110       120       130       140       150       160      
pF1KE6 KKRCHRDGMCCPSTRCNNGICIPVTESILTPHIPALDGTQHRDRNHGHYSNHDLGWQNLG
       .::: : .::::.. :.::::.   .. .  .:   . :  .. .. : :. : :..   
CCDS72 RKRCMRHAMCCPGNYCKNGICVSSDQNHFRGEI---EETITESFGNDH-STLD-GYSRRT
       120       130       140       150          160         170  

        170       180       190       200       210       220      
pF1KE6 RPHTKMSHIKGHEGDPCLRSSDCIEGFCCARHFWTKICKPVLHQGEVCTKQRKKGSHGLE
          .:: : ::.::. :::::::  :.:::::::.:::::::..:.::::.:.:::::::
CCDS72 TLSSKMYHTKGQEGSVCLRSSDCASGLCCARHFWSKICKPVLKEGQVCTKHRRKGSHGLE
            180       190       200       210       220       230  

        230       240       250          
pF1KE6 IFQRCDCAKGLSCKVWKDATYSSKA-RLHVCQKI
       ::::: :..::::.. ::   .:.. :::.::. 
CCDS72 IFQRCYCGEGLSCRIQKDHHQASNSSRLHTCQRH
            240       250       260      

>>CCDS6130.1 DKK4 gene_id:27121|Hs108|chr8                (224 aa)
 initn: 429 init1: 242 opt: 568  Z-score: 563.6  bits: 111.7 E(32554): 4.5e-25
Smith-Waterman score: 568; 42.2% identity (68.8% similar) in 199 aa overlap (65-259:34-221)

           40        50        60        70        80        90    
pF1KE6 LNSIKSSLGGETPGQAANRSAGMYQGLAFGGSKKGKNLGQAYPCSSDKECEVGRYCHSPH
                                     :..::..      : :: .:.. ..: .:.
CCDS61 AVLLGLSWLCSPLGALVLDFNNIRSSADLHGARKGSQ------CLSDTDCNTRKFCLQPR
            10        20        30        40              50       

          100       110       120       130         140       150  
pF1KE6 QGSSACMVCRRKKKRCHRDGMCCPSTRCNNGICIPVTES--ILTPHIPALDGTQHRDRNH
       . .  : .::  ..::.::.::::.: : : .:  . ..  ::  ..   ::: : . . 
CCDS61 DEKPFCATCRGLRRRCQRDAMCCPGTLCVNDVCTTMEDATPILERQLDEQDGT-HAEGTT
        60        70        80        90       100       110       

            160       170        180       190       200       210 
pF1KE6 GHYSNHDLGWQNLGRPHTKMSHI-KGHEGDPCLRSSDCIEGFCCARHFWTKICKPVLHQG
       ::  ...   :   .:  : :.  ::.::. :::. ::  :.::::::::::::::: .:
CCDS61 GHPVQEN---QPKRKPSIKKSQGRKGQEGESCLRTFDCGPGLCCARHFWTKICKPVLLEG
        120          130       140       150       160       170   

             220        230       240       250            
pF1KE6 EVCTKQRKKGS-HGLEIFQRCDCAKGLSCKVWKDATYSSKARLHVCQKI   
       .::... .: . .. ::::::::. :: :.  . ..  ..:::.:::::   
CCDS61 QVCSRRGHKDTAQAPEIFQRCDCGPGLLCRS-QLTSNRQHARLRVCQKIEKL
           180       190       200        210       220    




259 residues in 1 query   sequences
18511270 residues in 32554 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Tue Nov  8 15:02:00 2016 done: Tue Nov  8 15:02:01 2016
 Total Scan time:  1.510 Total Display time: -0.010

Function used was FASTA [36.3.4 Apr, 2011]