Result of FASTA (omim) for
pFN21AE6615
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE6615, 289 aa
1>>>pF1KE6615 289 - 289 aa - 289 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.0548+/-0.000366; mu= 12.0843+/- 0.023
mean_var=82.8249+/-16.070, 0's: 0 Z-trim(114.7): 6 B-trim: 31 in 1/52
Lambda= 0.140927
statistics sampled from 24641 (24647) to 24641 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.666), E-opt: 0.2 (0.289), width: 16
Scan time: 5.440
The best scores are: opt bits E(85289)
NP_981932 (OMIM: 274800,612025) iodotyrosine deiod ( 289) 1917 399.3 4.5e-111
NP_001158167 (OMIM: 274800,612025) iodotyrosine de ( 247) 1537 322.0 7.1e-88
NP_001158166 (OMIM: 274800,612025) iodotyrosine de ( 293) 1537 322.0 8.2e-88
XP_006715541 (OMIM: 274800,612025) PREDICTED: iodo ( 294) 1535 321.6 1.1e-87
XP_006715542 (OMIM: 274800,612025) PREDICTED: iodo ( 239) 1138 240.9 1.8e-63
NP_001305424 (OMIM: 274800,612025) iodotyrosine de ( 207) 1103 233.7 2.2e-61
>>NP_981932 (OMIM: 274800,612025) iodotyrosine deiodinas (289 aa)
initn: 1917 init1: 1917 opt: 1917 Z-score: 2115.1 bits: 399.3 E(85289): 4.5e-111
Smith-Waterman score: 1917; 99.7% identity (99.7% similar) in 289 aa overlap (1-289:1-289)
10 20 30 40 50 60
pF1KE6 MYFLTPILVAILCILVVWIFKNADRSMEKKKGEPRTRAEARPWVDEDLKDSSDLHQAEED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_981 MYFLTPILVAILCILVVWIFKNADRSMEKKKGEPRTRAEARPWVDEDLKDSSDLHQAEED
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 ADEWQESEENVEHIPFSHNHYPEKEMVKRSQEFYELLNKRRSVRFISNEQVPMEVIDNVI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_981 ADEWQESEENVEHIPFSHNHYPEKEMVKRSQEFYELLNKRRSVRFISNEQVPMEVIDNVI
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 RTAGTAPSGAHTEPWTFVVVKDPDVKHKIRKIIEEEEEINYMKRMGHRWVTDLKKLRTNW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_981 RTAGTAPSGAHTEPWTFVVVKDPDVKHKIRKIIEEEEEINYMKRMGHRWVTDLKKLRTNW
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE6 IKEYLDTAPILILIFKQVHGFAANGKKKVHYYNEISVSIACGILLAALQNAGLVTVTTTP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_981 IKEYLDTAPILILIFKQVHGFAANGKKKVHYYNEISVSIACGILLAALQNAGLVTVTTTP
190 200 210 220 230 240
250 260 270 280
pF1KE6 LNCGPRLRVLLGRPAHEKLPMLLPVGYPSKEATVPDLKRKPLDQIMVTV
::::::::::::::::::: :::::::::::::::::::::::::::::
NP_981 LNCGPRLRVLLGRPAHEKLLMLLPVGYPSKEATVPDLKRKPLDQIMVTV
250 260 270 280
>>NP_001158167 (OMIM: 274800,612025) iodotyrosine deiodi (247 aa)
initn: 1533 init1: 1533 opt: 1537 Z-score: 1698.6 bits: 322.0 E(85289): 7.1e-88
Smith-Waterman score: 1537; 95.9% identity (96.7% similar) in 241 aa overlap (1-241:1-241)
10 20 30 40 50 60
pF1KE6 MYFLTPILVAILCILVVWIFKNADRSMEKKKGEPRTRAEARPWVDEDLKDSSDLHQAEED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MYFLTPILVAILCILVVWIFKNADRSMEKKKGEPRTRAEARPWVDEDLKDSSDLHQAEED
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 ADEWQESEENVEHIPFSHNHYPEKEMVKRSQEFYELLNKRRSVRFISNEQVPMEVIDNVI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ADEWQESEENVEHIPFSHNHYPEKEMVKRSQEFYELLNKRRSVRFISNEQVPMEVIDNVI
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 RTAGTAPSGAHTEPWTFVVVKDPDVKHKIRKIIEEEEEINYMKRMGHRWVTDLKKLRTNW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RTAGTAPSGAHTEPWTFVVVKDPDVKHKIRKIIEEEEEINYMKRMGHRWVTDLKKLRTNW
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE6 IKEYLDTAPILILIFKQVHGFAANGKKKVHYYNEISVSIACGILLAALQNAGLVTVTTTP
::::::::::::::::::::::::::::::::::::::::::::::::: : . .
NP_001 IKEYLDTAPILILIFKQVHGFAANGKKKVHYYNEISVSIACGILLAALQVFGKIILKELA
190 200 210 220 230 240
250 260 270 280
pF1KE6 LNCGPRLRVLLGRPAHEKLPMLLPVGYPSKEATVPDLKRKPLDQIMVTV
:
NP_001 LISFLNL
>>NP_001158166 (OMIM: 274800,612025) iodotyrosine deiodi (293 aa)
initn: 1533 init1: 1533 opt: 1537 Z-score: 1697.5 bits: 322.0 E(85289): 8.2e-88
Smith-Waterman score: 1537; 98.7% identity (99.1% similar) in 234 aa overlap (1-233:1-234)
10 20 30 40 50 60
pF1KE6 MYFLTPILVAILCILVVWIFKNADRSMEKKKGEPRTRAEARPWVDEDLKDSSDLHQAEED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MYFLTPILVAILCILVVWIFKNADRSMEKKKGEPRTRAEARPWVDEDLKDSSDLHQAEED
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 ADEWQESEENVEHIPFSHNHYPEKEMVKRSQEFYELLNKRRSVRFISNEQVPMEVIDNVI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ADEWQESEENVEHIPFSHNHYPEKEMVKRSQEFYELLNKRRSVRFISNEQVPMEVIDNVI
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 RTAGTAPSGAHTEPWTFVVVKDPDVKHKIRKIIEEEEEINYMKRMGHRWVTDLKKLRTNW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RTAGTAPSGAHTEPWTFVVVKDPDVKHKIRKIIEEEEEINYMKRMGHRWVTDLKKLRTNW
130 140 150 160 170 180
190 200 210 220 230
pF1KE6 IKEYLDTAPILILIFKQVHGFAANGKKKVHYYNEISVSIACGILLAALQ-NAGLVTVTTT
::::::::::::::::::::::::::::::::::::::::::::::::: : :.
NP_001 IKEYLDTAPILILIFKQVHGFAANGKKKVHYYNEISVSIACGILLAALQVNNGITMRHQT
190 200 210 220 230 240
240 250 260 270 280
pF1KE6 PLNCGPRLRVLLGRPAHEKLPMLLPVGYPSKEATVPDLKRKPLDQIMVTV
NP_001 ARHRHLIEGPGRSSEACSKLSSQGCPECRSGDCHYHSSQLWPSTEGAPGPPRT
250 260 270 280 290
>>XP_006715541 (OMIM: 274800,612025) PREDICTED: iodotyro (294 aa)
initn: 1533 init1: 1533 opt: 1535 Z-score: 1695.2 bits: 321.6 E(85289): 1.1e-87
Smith-Waterman score: 1535; 98.3% identity (98.7% similar) in 235 aa overlap (1-233:1-235)
10 20 30 40 50 60
pF1KE6 MYFLTPILVAILCILVVWIFKNADRSMEKKKGEPRTRAEARPWVDEDLKDSSDLHQAEED
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MYFLTPILVAILCILVVWIFKNADRSMEKKKGEPRTRAEARPWVDEDLKDSSDLHQAEED
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 ADEWQESEENVEHIPFSHNHYPEKEMVKRSQEFYELLNKRRSVRFISNEQVPMEVIDNVI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ADEWQESEENVEHIPFSHNHYPEKEMVKRSQEFYELLNKRRSVRFISNEQVPMEVIDNVI
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 RTAGTAPSGAHTEPWTFVVVKDPDVKHKIRKIIEEEEEINYMKRMGHRWVTDLKKLRTNW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RTAGTAPSGAHTEPWTFVVVKDPDVKHKIRKIIEEEEEINYMKRMGHRWVTDLKKLRTNW
130 140 150 160 170 180
190 200 210 220 230
pF1KE6 IKEYLDTAPILILIFKQVHGFAANGKKKVHYYNEISVSIACGILLAALQ--NAGLVTVTT
::::::::::::::::::::::::::::::::::::::::::::::::: : :.
XP_006 IKEYLDTAPILILIFKQVHGFAANGKKKVHYYNEISVSIACGILLAALQQVNNGITMRHQ
190 200 210 220 230 240
240 250 260 270 280
pF1KE6 TPLNCGPRLRVLLGRPAHEKLPMLLPVGYPSKEATVPDLKRKPLDQIMVTV
XP_006 TARHRHLIEGPGRSSEACSKLSSQGCPECRSGDCHYHSSQLWPSTEGAPGPPRT
250 260 270 280 290
>>XP_006715542 (OMIM: 274800,612025) PREDICTED: iodotyro (239 aa)
initn: 1136 init1: 1136 opt: 1138 Z-score: 1260.4 bits: 240.9 E(85289): 1.8e-63
Smith-Waterman score: 1138; 97.7% identity (98.3% similar) in 176 aa overlap (60-233:5-180)
30 40 50 60 70 80
pF1KE6 KKGEPRTRAEARPWVDEDLKDSSDLHQAEEDADEWQESEENVEHIPFSHNHYPEKEMVKR
::::::::::::::::::::::::::::::
XP_006 MVCADADEWQESEENVEHIPFSHNHYPEKEMVKR
10 20 30
90 100 110 120 130 140
pF1KE6 SQEFYELLNKRRSVRFISNEQVPMEVIDNVIRTAGTAPSGAHTEPWTFVVVKDPDVKHKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 SQEFYELLNKRRSVRFISNEQVPMEVIDNVIRTAGTAPSGAHTEPWTFVVVKDPDVKHKI
40 50 60 70 80 90
150 160 170 180 190 200
pF1KE6 RKIIEEEEEINYMKRMGHRWVTDLKKLRTNWIKEYLDTAPILILIFKQVHGFAANGKKKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 RKIIEEEEEINYMKRMGHRWVTDLKKLRTNWIKEYLDTAPILILIFKQVHGFAANGKKKV
100 110 120 130 140 150
210 220 230 240 250 260
pF1KE6 HYYNEISVSIACGILLAALQ--NAGLVTVTTTPLNCGPRLRVLLGRPAHEKLPMLLPVGY
:::::::::::::::::::: : :.
XP_006 HYYNEISVSIACGILLAALQQVNNGITMRHQTARHRHLIEGPGRSSEACSKLSSQGCPEC
160 170 180 190 200 210
>>NP_001305424 (OMIM: 274800,612025) iodotyrosine deiodi (207 aa)
initn: 1092 init1: 1092 opt: 1103 Z-score: 1222.9 bits: 233.7 E(85289): 2.2e-61
Smith-Waterman score: 1103; 82.5% identity (88.2% similar) in 211 aa overlap (79-289:4-207)
50 60 70 80 90 100
pF1KE6 KDSSDLHQAEEDADEWQESEENVEHIPFSHNHYPEKEMVKRSQEFYELLNKRRSVRFISN
: .:.:.. : . . .:. .: . :
NP_001 MLMNGKNQKKMLNTSPSLITTILRRKWLRGLRN
10 20 30
110 120 130 140 150 160
pF1KE6 EQVPMEVIDNVIRTAGTAPSGAHTEPWTFVVVKDPDVKHKIRKIIEEEEEINYMKRMGHR
.. :: :::::::::::::::::::::::::::::::::::::::::::::
NP_001 ------FMNFSIRD-GTAPSGAHTEPWTFVVVKDPDVKHKIRKIIEEEEEINYMKRMGHR
40 50 60 70 80
170 180 190 200 210 220
pF1KE6 WVTDLKKLRTNWIKEYLDTAPILILIFKQVHGFAANGKKKVHYYNEISVSIACGILLAAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 WVTDLKKLRTNWIKEYLDTAPILILIFKQVHGFAANGKKKVHYYNEISVSIACGILLAAL
90 100 110 120 130 140
230 240 250 260 270 280
pF1KE6 QNAGLVTVTTTPLNCGPRLRVLLGRPAHEKLPMLLPVGYPSKEATVPDLKRKPLDQIMVT
::::::::::::::::::::::::::::::: ::::::::::::::::::::::::::::
NP_001 QNAGLVTVTTTPLNCGPRLRVLLGRPAHEKLLMLLPVGYPSKEATVPDLKRKPLDQIMVT
150 160 170 180 190 200
pF1KE6 V
:
NP_001 V
289 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Nov 8 14:47:48 2016 done: Tue Nov 8 14:47:49 2016
Total Scan time: 5.440 Total Display time: -0.030
Function used was FASTA [36.3.4 Apr, 2011]