Result of FASTA (ccds) for
pFN21AE6611
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE6611, 267 aa
1>>>pF1KE6611 267 - 267 aa - 267 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.1942+/-0.00084; mu= 11.5840+/- 0.051
mean_var=87.9733+/-17.735, 0's: 0 Z-trim(109.1): 35 B-trim: 0 in 0/50
Lambda= 0.136741
statistics sampled from 10592 (10626) to 10592 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.683), E-opt: 0.2 (0.326), width: 16
Scan time: 1.660
The best scores are: opt bits E(32554)
CCDS7988.1 MS4A12 gene_id:54860|Hs108|chr11 ( 267) 1750 354.7 3.9e-98
CCDS53638.1 MS4A12 gene_id:54860|Hs108|chr11 ( 221) 831 173.4 1.3e-43
CCDS7990.1 MS4A8 gene_id:83661|Hs108|chr11 ( 250) 506 109.3 2.8e-24
CCDS44617.1 MS4A15 gene_id:219995|Hs108|chr11 ( 240) 431 94.5 7.7e-20
CCDS7991.1 MS4A15 gene_id:219995|Hs108|chr11 ( 147) 337 75.8 1.9e-14
CCDS7982.1 MS4A4A gene_id:51338|Hs108|chr11 ( 239) 289 66.4 2.1e-11
CCDS60802.1 MS4A15 gene_id:219995|Hs108|chr11 ( 199) 281 64.8 5.3e-11
>>CCDS7988.1 MS4A12 gene_id:54860|Hs108|chr11 (267 aa)
initn: 1750 init1: 1750 opt: 1750 Z-score: 1875.3 bits: 354.7 E(32554): 3.9e-98
Smith-Waterman score: 1750; 100.0% identity (100.0% similar) in 267 aa overlap (1-267:1-267)
10 20 30 40 50 60
pF1KE6 MMSSKPTSHAEVNETIPNPYPPSSFMAPGFQQPLGSINLENQAQGAQRAQPYGITSPGIF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS79 MMSSKPTSHAEVNETIPNPYPPSSFMAPGFQQPLGSINLENQAQGAQRAQPYGITSPGIF
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 ASSQPGQGNIQMINPSVGTAVMNFKEEAKALGVIQIMVGLMHIGFGIVLCLISFSFREVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS79 ASSQPGQGNIQMINPSVGTAVMNFKEEAKALGVIQIMVGLMHIGFGIVLCLISFSFREVL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 GFASTAVIGGYPFWGGLSFIISGSLSVSASKELSRCLVKGSLGMNIVSSILAFIGVILLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS79 GFASTAVIGGYPFWGGLSFIISGSLSVSASKELSRCLVKGSLGMNIVSSILAFIGVILLL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE6 VDMCINGVAGQDYWAVLSGKGISATLMIFSLLEFFVACATAHFANQANTTTNMSVLVIPN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS79 VDMCINGVAGQDYWAVLSGKGISATLMIFSLLEFFVACATAHFANQANTTTNMSVLVIPN
190 200 210 220 230 240
250 260
pF1KE6 MYESNPVTPASSSAPPRCNNYSANAPK
:::::::::::::::::::::::::::
CCDS79 MYESNPVTPASSSAPPRCNNYSANAPK
250 260
>>CCDS53638.1 MS4A12 gene_id:54860|Hs108|chr11 (221 aa)
initn: 831 init1: 831 opt: 831 Z-score: 896.7 bits: 173.4 E(32554): 1.3e-43
Smith-Waterman score: 1339; 82.8% identity (82.8% similar) in 267 aa overlap (1-267:1-221)
10 20 30 40 50 60
pF1KE6 MMSSKPTSHAEVNETIPNPYPPSSFMAPGFQQPLGSINLENQAQGAQRAQPYGITSPGIF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS53 MMSSKPTSHAEVNETIPNPYPPSSFMAPGFQQPLGSINLENQAQGAQRAQPYGITSPGIF
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 ASSQPGQGNIQMINPSVGTAVMNFKEEAKALGVIQIMVGLMHIGFGIVLCLISFSFREVL
::::::::::::::::::::::::::::::::
CCDS53 ASSQPGQGNIQMINPSVGTAVMNFKEEAKALG----------------------------
70 80 90
130 140 150 160 170 180
pF1KE6 GFASTAVIGGYPFWGGLSFIISGSLSVSASKELSRCLVKGSLGMNIVSSILAFIGVILLL
::::::::::::::::::::::::::::::::::::::::::
CCDS53 ------------------FIISGSLSVSASKELSRCLVKGSLGMNIVSSILAFIGVILLL
100 110 120 130
190 200 210 220 230 240
pF1KE6 VDMCINGVAGQDYWAVLSGKGISATLMIFSLLEFFVACATAHFANQANTTTNMSVLVIPN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS53 VDMCINGVAGQDYWAVLSGKGISATLMIFSLLEFFVACATAHFANQANTTTNMSVLVIPN
140 150 160 170 180 190
250 260
pF1KE6 MYESNPVTPASSSAPPRCNNYSANAPK
:::::::::::::::::::::::::::
CCDS53 MYESNPVTPASSSAPPRCNNYSANAPK
200 210 220
>>CCDS7990.1 MS4A8 gene_id:83661|Hs108|chr11 (250 aa)
initn: 327 init1: 133 opt: 506 Z-score: 549.4 bits: 109.3 E(32554): 2.8e-24
Smith-Waterman score: 506; 42.5% identity (66.4% similar) in 226 aa overlap (52-256:23-240)
30 40 50 60 70
pF1KE6 PSSFMAPGFQQPLGSINLENQAQGAQRAQPYGITSPGI------FASSQPGQGNIQMINP
: .: ::: . .::: . :
CCDS79 MNSMTSAVPVANSVLVVAPHNGYPVT-PGIMSHVPLYPNSQPQVHLVPGNPP
10 20 30 40 50
80 90 100 110 120
pF1KE6 SV-----GTAVMNFKEEAKALGVIQIMVGLMHIGFGIVLCLISFSFREVLG-FASTAVIG
:. : :.. .:.:.::.:::..:: :::.: .. . ..: . : . :
CCDS79 SLVSNVNGQPVQKALKEGKTLGAIQIIIGLAHIGLGSIMATV------LVGEYLSISFYG
60 70 80 90 100
130 140 150 160 170 180
pF1KE6 GYPFWGGLSFIISGSLSVSA-SKELSRCLVKGSLGMNIVSSILAFIGVILLLVDMCI-NG
:.:::::: :::::::::.: .. : ::..::::.::::.: . .::::...:. : .
CCDS79 GFPFWGGLWFIISGSLSVAAENQPYSYCLLSGSLGLNIVSAICSAVGVILFITDLSIPHP
110 120 130 140 150 160
190 200 210 220 230 240
pF1KE6 VAGQDY----WAVLSGKGISATLMIFSLLEFFVACATAHFANQ--ANTTTNMSVLVIPNM
: :: :.: : .::..:..: :::: .:::..::. : ..:.:: . ::.
CCDS79 YAYPDYYPYAWGVNPGMAISGVLLVFCLLEFGIACASSHFGCQLVCCQSSNVSV-IYPNI
170 180 190 200 210 220
250 260
pF1KE6 YESNPV-TPASSSAPPRCNNYSANAPK
: .::: :: ..::
CCDS79 YAANPVITPEPVTSPPSYSSEIQANK
230 240 250
>>CCDS44617.1 MS4A15 gene_id:219995|Hs108|chr11 (240 aa)
initn: 447 init1: 221 opt: 431 Z-score: 469.7 bits: 94.5 E(32554): 7.7e-20
Smith-Waterman score: 446; 35.5% identity (60.4% similar) in 265 aa overlap (2-260:1-232)
10 20 30 40 50
pF1KE6 MMSSKPTSHAEVNETIPNPY----PPSSFMAPGFQQPLGSINLENQAQGAQRAQPYGITS
::. :.:.. :: :: ... .. :: : ...:. ::: .
CCDS44 MSAAPASNGVFVVIPPNNASGLCPPPAILPTSMCQPPGIMQFEEPPLGAQ--------T
10 20 30 40 50
60 70 80 90 100 110
pF1KE6 PGIFASSQPGQGNIQMINPSVGTAVMNFKEEAKALGVIQIMVGLMHIGFGIVLCLISFSF
: ..:: :.. . . : :.::..::..::.:.::: :: ..
CCDS44 P---RATQP---------PDLRPVETFLTGEPKVLGTVQILIGLIHLGFGSVLLMVR---
60 70 80 90
120 130 140 150 160 170
pF1KE6 REVLGFASTAVIGGYPFWGGLSFIISGSLSVSASKELSRCLVKGSLGMNIVSSILAFIGV
: .:. . :: ::::: :::::::::.: :. . :::..::: ::.: . :: :.
CCDS44 RGHVGI--FFIEGGVPFWGGACFIISGSLSVAAEKNHTSCLVRSSLGTNILSVMAAFAGT
100 110 120 130 140 150
180 190 200 210 220 230
pF1KE6 ILLLVDMCINGVAGQDYWAVLSGKGISATLMIFSLLEFFVACATAHFANQA-NTTTNMSV
.::.:. ::...: .: :.: ::..::::.: . ::. :: .. .. :
CCDS44 AILLMDF---GVTNRDV-----DRGYLAVLTIFTVLEFFTAVIAMHFGCQAIHAQASAPV
160 170 180 190 200
240 250 260
pF1KE6 LVIPNMYESNPVTPA-SSSAPPRCNNYSANAPK
. .:: . .. :. ..:::: .:
CCDS44 IFLPNAFSADFNIPSPAASAPPAYDNVAYAQGVV
210 220 230 240
>>CCDS7991.1 MS4A15 gene_id:219995|Hs108|chr11 (147 aa)
initn: 330 init1: 221 opt: 337 Z-score: 372.7 bits: 75.8 E(32554): 1.9e-14
Smith-Waterman score: 337; 44.0% identity (69.4% similar) in 134 aa overlap (129-260:14-139)
100 110 120 130 140 150
pF1KE6 GLMHIGFGIVLCLISFSFREVLGFASTAVIGGYPFWGGLSFIISGSLSVSASKELSRCLV
:: ::::: :::::::::.: :. . :::
CCDS79 MVRRGHVGIFFIEGGVPFWGGACFIISGSLSVAAEKNHTSCLV
10 20 30 40
160 170 180 190 200 210
pF1KE6 KGSLGMNIVSSILAFIGVILLLVDMCINGVAGQDYWAVLSGKGISATLMIFSLLEFFVAC
..::: ::.: . :: :. .::.:. ::...: .: :.: ::..::::.:
CCDS79 RSSLGTNILSVMAAFAGTAILLMDF---GVTNRDV-----DRGYLAVLTIFTVLEFFTAV
50 60 70 80 90
220 230 240 250 260
pF1KE6 ATAHFANQA-NTTTNMSVLVIPNMYESNPVTPA-SSSAPPRCNNYSANAPK
. ::. :: .. .. :. .:: . .. :. ..:::: .:
CCDS79 IAMHFGCQAIHAQASAPVIFLPNAFSADFNIPSPAASAPPAYDNVAYAQGVV
100 110 120 130 140
>>CCDS7982.1 MS4A4A gene_id:51338|Hs108|chr11 (239 aa)
initn: 246 init1: 173 opt: 289 Z-score: 318.3 bits: 66.4 E(32554): 2.1e-11
Smith-Waterman score: 318; 31.8% identity (63.7% similar) in 223 aa overlap (44-249:24-235)
20 30 40 50 60 70
pF1KE6 ETIPNPYPPSSFMAPGFQQPLGSINLENQAQGAQRAQPYGITSPGIFASSQPGQGNIQMI
:: ..:.: : ..::. : ::. .:
CCDS79 MHQTYSRHCRPEESTFSAAMTTMQGMEQAMP-G-AGPGV-----PQLGNMAVI
10 20 30 40
80 90 100 110 120 130
pF1KE6 NPSVGTAVMN--FKEEAKALGVIQIMVGLMHIGFGI-VLCLISFSFREVLGFASTAVIGG
. . .... .: : :.:::.::...:: ...:: ..:. : .. : .: :
CCDS79 HSHLWKGLQEKFLKGEPKVLGVVQILTALMSLSMGITMMCMASNTY----GSNPISVYIG
50 60 70 80 90 100
140 150 160 170 180
pF1KE6 YPFWGGLSFIISGSLSVSASKELSRCLVKGSLGMNIVSSILAFIGVILLLVDM-------
: .::.. ::::::::..:. . .. ::.:::::::.::.:: :... ..
CCDS79 YTIWGSVMFIISGSLSIAAGIRTTKGLVRGSLGMNITSSVLAASGILINTFSLAFYSFHH
110 120 130 140 150 160
190 200 210 220 230
pF1KE6 --C-INGVAGQDYWAVLSGKGISATLMIFSLLEFFVACATAHFANQA-NTTTNMSVLVIP
: : ... . .. :... ....:.::: .: . . :. .. : . ::..:
CCDS79 PYCNYYGNSNNCHGTMSILMGLDGMVLLLSVLEFCIAVSLSAFGCKVLCCTPGGVVLILP
170 180 190 200 210 220
240 250 260
pF1KE6 N---MYESNPVTPASSSAPPRCNNYSANAPK
. : :. ::
CCDS79 SHSHMAETASPTPLNEV
230
>>CCDS60802.1 MS4A15 gene_id:219995|Hs108|chr11 (199 aa)
initn: 301 init1: 160 opt: 281 Z-score: 311.0 bits: 64.8 E(32554): 5.3e-11
Smith-Waterman score: 281; 42.1% identity (69.8% similar) in 126 aa overlap (137-260:74-191)
110 120 130 140 150 160
pF1KE6 IVLCLISFSFREVLGFASTAVIGGYPFWGGLSFIISGSLSVSASKELSRCLVKGSLGMNI
:.:::::::::.: :. . :::..::: ::
CCDS60 EPPLGAQTPRATQPPDLRPVETFLTGEPKVLGFIISGSLSVAAEKNHTSCLVRSSLGTNI
50 60 70 80 90 100
170 180 190 200 210 220
pF1KE6 VSSILAFIGVILLLVDMCINGVAGQDYWAVLSGKGISATLMIFSLLEFFVACATAHFANQ
.: . :: :. .::.:. ::...: .: :.: ::..::::.: . ::. :
CCDS60 LSVMAAFAGTAILLMDF---GVTNRDV-----DRGYLAVLTIFTVLEFFTAVIAMHFGCQ
110 120 130 140 150
230 240 250 260
pF1KE6 A-NTTTNMSVLVIPNMYESNPVTPA-SSSAPPRCNNYSANAPK
: .. .. :. .:: . .. :. ..:::: .:
CCDS60 AIHAQASAPVIFLPNAFSADFNIPSPAASAPPAYDNVAYAQGVV
160 170 180 190
267 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Nov 8 14:45:43 2016 done: Tue Nov 8 14:45:43 2016
Total Scan time: 1.660 Total Display time: -0.030
Function used was FASTA [36.3.4 Apr, 2011]