FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KE6601, 235 aa
  1>>>pF1KE6601 235 - 235 aa - 235 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 5.1363+/-0.000319; mu= 15.4413+/- 0.020
 mean_var=63.8786+/-12.288, 0's: 0 Z-trim(115.3): 4  B-trim: 0 in 0/55
 Lambda= 0.160471
 statistics sampled from 25588 (25592) to 25588 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.678), E-opt: 0.2 (0.3), width:  16
 Scan time:  4.510

The best scores are:                                      opt bits E(85289)
NP_997274 (OMIM: 607814,608415) regulator of G-pro ( 235) 1495 354.4   1e-97
XP_005248559 (OMIM: 610890) PREDICTED: regulator o ( 227)  163 46.0 6.5e-05
NP_001025046 (OMIM: 610890) regulator of G-protein ( 257)  163 46.0 7.2e-05


>>NP_997274 (OMIM: 607814,608415) regulator of G-protein  (235 aa)
 initn: 1495 init1: 1495 opt: 1495  Z-score: 1875.5  bits: 354.4 E(85289): 1e-97
Smith-Waterman score: 1495; 100.0% identity (100.0% similar) in 235 aa overlap (1-235:1-235)

               10        20        30        40        50        60
pF1KE6 MAREECKALLDGLNKTTACYHHLVLTVGGSADSQNLRQELQKTRQKAQELAVSTCARLTA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_997 MAREECKALLDGLNKTTACYHHLVLTVGGSADSQNLRQELQKTRQKAQELAVSTCARLTA
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE6 VLRDRGLAADERAEFERLWVAFSGCLDLLEADMRRALELGAAFPLHAPRRPLVRTGVAGA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_997 VLRDRGLAADERAEFERLWVAFSGCLDLLEADMRRALELGAAFPLHAPRRPLVRTGVAGA
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KE6 SSGVAARALSTRSLRLEAEGDFDVADLRELEREVLQVGEMIDNMEMKVNVPRWTVQARQA
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_997 SSGVAARALSTRSLRLEAEGDFDVADLRELEREVLQVGEMIDNMEMKVNVPRWTVQARQA
              130       140       150       160       170       180

              190       200       210       220       230     
pF1KE6 AGAELLSTVSAGPSSVVSLQERGGGCDPRKALAAILFGAVLLAAVALAVCVAKLS
       :::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_997 AGAELLSTVSAGPSSVVSLQERGGGCDPRKALAAILFGAVLLAAVALAVCVAKLS
              190       200       210       220       230     

>>XP_005248559 (OMIM: 610890) PREDICTED: regulator of G-  (227 aa)
 initn:  99 init1:  58 opt: 163  Z-score: 209.1  bits: 46.0 E(85289): 6.5e-05
Smith-Waterman score: 163; 29.9% identity (67.3% similar) in 107 aa overlap (2-106:49-152)

                                            10        20         30
pF1KE6                              MAREECKALLDGLNKTTACYHHLVLTVGG-S
                                     : ..:: :.. .:  .: :..::...:  :
XP_005 SIFQISKPPLQSGDWERRGSGSESAHKTQRALDDCKMLVQEFNTQVALYRELVISIGDVS
       20        30        40        50        60        70        

               40        50        60        70         80         
pF1KE6 ADSQNLRQELQKTRQKAQELAVSTCARLTAVLRDRGLAADE-RAEFERLWVAFSGCLDLL
       ..  .:: :..::: :. :.: ..  .:.:.    :    : . :. ::.. .. ::.. 
XP_005 VSCPSLRAEMHKTRTKGCEMARQAHQKLAAI---SGPEDGEIHPEICRLYIQLQCCLEMY
       80        90       100          110       120       130     

      90       100       110       120       130       140         
pF1KE6 EADMRRALELGAAFPLHAPRRPLVRTGVAGASSGVAARALSTRSLRLEAEGDFDVADLRE
        ..: ... : ... .:                                           
XP_005 TTEMLKSICLLGSLQFHRKGKEPGGGTKSLDCKIEESAETPALEDSSSSPVDSQQHSWQV
         140       150       160       170       180       190     

>>NP_001025046 (OMIM: 610890) regulator of G-protein sig  (257 aa)
 initn:  99 init1:  58 opt: 163  Z-score: 208.3  bits: 46.0 E(85289): 7.2e-05
Smith-Waterman score: 163; 29.9% identity (67.3% similar) in 107 aa overlap (2-106:49-152)

                                            10        20         30
pF1KE6                              MAREECKALLDGLNKTTACYHHLVLTVGG-S
                                     : ..:: :.. .:  .: :..::...:  :
NP_001 SIFQISKPPLQSGDWERRGSGSESAHKTQRALDDCKMLVQEFNTQVALYRELVISIGDVS
       20        30        40        50        60        70        

               40        50        60        70         80         
pF1KE6 ADSQNLRQELQKTRQKAQELAVSTCARLTAVLRDRGLAADE-RAEFERLWVAFSGCLDLL
       ..  .:: :..::: :. :.: ..  .:.:.    :    : . :. ::.. .. ::.. 
NP_001 VSCPSLRAEMHKTRTKGCEMARQAHQKLAAI---SGPEDGEIHPEICRLYIQLQCCLEMY
       80        90       100          110       120       130     

      90       100       110       120       130       140         
pF1KE6 EADMRRALELGAAFPLHAPRRPLVRTGVAGASSGVAARALSTRSLRLEAEGDFDVADLRE
        ..: ... : ... .:                                           
NP_001 TTEMLKSICLLGSLQFHRKGKEPGGGTKSLDCKIEESAETPALEDSSSSPVDSQQHSWQV
         140       150       160       170       180       190     




235 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Tue Nov  8 14:40:40 2016 done: Tue Nov  8 14:40:41 2016
 Total Scan time:  4.510 Total Display time: -0.030

Function used was FASTA [36.3.4 Apr, 2011]