Result of FASTA (omim) for
pFN21AE6588
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE6588, 177 aa
1>>>pF1KE6588 177 - 177 aa - 177 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.7603+/-0.000398; mu= 13.8068+/- 0.025
mean_var=193.8604+/-37.224, 0's: 0 Z-trim(119.9): 127 B-trim: 183 in 1/52
Lambda= 0.092115
statistics sampled from 34364 (34511) to 34364 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.72), E-opt: 0.2 (0.405), width: 16
Scan time: 3.130
The best scores are: opt bits E(85289)
NP_112229 (OMIM: 608819) keratin-associated protei ( 177) 1472 206.9 1.4e-53
NP_112228 (OMIM: 608820) keratin-associated protei ( 167) 1191 169.5 2.4e-42
NP_114163 (OMIM: 608822) keratin-associated protei ( 174) 1132 161.7 5.5e-40
NP_001244234 (OMIM: 608821) keratin-associated pro ( 121) 883 128.4 4.2e-30
NP_005544 (OMIM: 148021) keratin-associated protei ( 169) 380 61.7 6.6e-10
NP_001005922 (OMIM: 148022) keratin-associated pro ( 278) 353 58.5 1e-08
NP_787054 (OMIM: 600064) keratin-associated protei ( 163) 218 40.2 0.002
NP_853630 (OMIM: 608718) keratin-associated protei ( 172) 201 38.0 0.0097
>>NP_112229 (OMIM: 608819) keratin-associated protein 1- (177 aa)
initn: 1472 init1: 1472 opt: 1472 Z-score: 1082.9 bits: 206.9 E(85289): 1.4e-53
Smith-Waterman score: 1472; 100.0% identity (100.0% similar) in 177 aa overlap (1-177:1-177)
10 20 30 40 50 60
pF1KE6 MACCQTSFCGFPSCSTSGTCGSSCCQPSCCETSSCQPRCCETSCCQPSCCQTSFCGFPSF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_112 MACCQTSFCGFPSCSTSGTCGSSCCQPSCCETSSCQPRCCETSCCQPSCCQTSFCGFPSF
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 STGGTCDSSCCQPSCCETSCCQPSCYQTSSCGTGCGIGGGIGYGQEGSSGAVSTRIRWCR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_112 STGGTCDSSCCQPSCCETSCCQPSCYQTSSCGTGCGIGGGIGYGQEGSSGAVSTRIRWCR
70 80 90 100 110 120
130 140 150 160 170
pF1KE6 PDCRVEGTCLPPCCVVSCTPPSCCQLHHAEASCCRPSYCGQSCCRPVCCCYCSEPTC
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_112 PDCRVEGTCLPPCCVVSCTPPSCCQLHHAEASCCRPSYCGQSCCRPVCCCYCSEPTC
130 140 150 160 170
>>NP_112228 (OMIM: 608820) keratin-associated protein 1- (167 aa)
initn: 1170 init1: 1170 opt: 1191 Z-score: 881.4 bits: 169.5 E(85289): 2.4e-42
Smith-Waterman score: 1299; 89.8% identity (92.7% similar) in 177 aa overlap (1-177:1-167)
10 20 30 40 50 60
pF1KE6 MACCQTSFCGFPSCSTSGTCGSSCCQPSCCETSSCQPRCCETSCCQPSCCQTSFCGFPSF
:.::::::::.:::::::::::::::::::::: :::::::::::::::::
NP_112 MTCCQTSFCGYPSCSTSGTCGSSCCQPSCCETS----------CCQPSCCQTSFCGFPSF
10 20 30 40 50
70 80 90 100 110 120
pF1KE6 STGGTCDSSCCQPSCCETSCCQPSCYQTSSCGTGCGIGGGIGYGQEGSSGAVSTRIRWCR
::.:::.:::::::::::::::::: ::::::::::::::::::::::::::::::::::
NP_112 STSGTCSSSCCQPSCCETSCCQPSCCQTSSCGTGCGIGGGIGYGQEGSSGAVSTRIRWCR
60 70 80 90 100 110
130 140 150 160 170
pF1KE6 PDCRVEGTCLPPCCVVSCTPPSCCQLHHAEASCCRPSYCGQSCCRPVCCCYCSEPTC
:::::::::::::::::::::.::::::::::::::::::::::::::::: ::::
NP_112 PDCRVEGTCLPPCCVVSCTPPTCCQLHHAEASCCRPSYCGQSCCRPVCCCYSCEPTC
120 130 140 150 160
>>NP_114163 (OMIM: 608822) keratin-associated protein 1- (174 aa)
initn: 1105 init1: 1105 opt: 1132 Z-score: 838.8 bits: 161.7 E(85289): 5.5e-40
Smith-Waterman score: 1162; 80.2% identity (84.0% similar) in 187 aa overlap (1-177:1-174)
10 20 30 40 50 60
pF1KE6 MACCQTSFCGFPSCSTSGTCGSSCCQPSCCETSSCQPRCCETSCCQPSCCQTSFCGFPSF
:.::::::::.:: : ::::::::::::::::: :::: :::::::::::
NP_114 MTCCQTSFCGYPSFSISGTCGSSCCQPSCCETS----------CCQPRSCQTSFCGFPSF
10 20 30 40 50
70 80 90 100 110
pF1KE6 STGGTCDSSCCQPSCCETSCCQPSCYQTS----------SCGTGCGIGGGIGYGQEGSSG
::.:::.:::::::::::::::::: .:: ::::::::::::.::::::::
NP_114 STSGTCSSSCCQPSCCETSCCQPSCCETSCCQPSCCQISSCGTGCGIGGGISYGQEGSSG
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE6 AVSTRIRWCRPDCRVEGTCLPPCCVVSCTPPSCCQLHHAEASCCRPSYCGQSCCRPVCCC
:::::::::::: ::::: ::::::::::::::::::::.::::::::::::::::::::
NP_114 AVSTRIRWCRPDSRVEGTYLPPCCVVSCTPPSCCQLHHAQASCCRPSYCGQSCCRPVCCC
120 130 140 150 160 170
pF1KE6 YCSEPTC
::::
NP_114 ---EPTC
>>NP_001244234 (OMIM: 608821) keratin-associated protein (121 aa)
initn: 883 init1: 883 opt: 883 Z-score: 661.5 bits: 128.4 E(85289): 4.2e-30
Smith-Waterman score: 883; 89.1% identity (95.8% similar) in 119 aa overlap (59-177:3-121)
30 40 50 60 70 80
pF1KE6 CCETSSCQPRCCETSCCQPSCCQTSFCGFPSFSTGGTCDSSCCQPSCCETSCCQPSCYQT
: ::.::: :::::::::::::::::: ::
NP_001 MASCSTSGTCGSSCCQPSCCETSCCQPSCCQT
10 20 30
90 100 110 120 130 140
pF1KE6 SSCGTGCGIGGGIGYGQEGSSGAVSTRIRWCRPDCRVEGTCLPPCCVVSCTPPSCCQLHH
::::::::::::::::::::.:.::::::::.:::.::::::::: .:::::::::::::
NP_001 SSCGTGCGIGGGIGYGQEGSGGSVSTRIRWCHPDCHVEGTCLPPCYLVSCTPPSCCQLHH
40 50 60 70 80 90
150 160 170
pF1KE6 AEASCCRPSYCGQSCCRPVCCCYCSEPTC
::::::::::::::::::.:::.: ::::
NP_001 AEASCCRPSYCGQSCCRPACCCHCCEPTC
100 110 120
>>NP_005544 (OMIM: 148021) keratin-associated protein 5- (169 aa)
initn: 305 init1: 206 opt: 380 Z-score: 298.8 bits: 61.7 E(85289): 6.6e-10
Smith-Waterman score: 438; 38.7% identity (51.3% similar) in 191 aa overlap (1-177:1-159)
10 20 30 40 50
pF1KE6 MACCQTSF-CGFPSC----STSGTCGSSC--CQPSCCE-TSSCQPRCCETSCCQPSCCQT
:.:: : :: :: :. :.:::.: : :::: . :.: :: . :. : :
NP_005 MGCCGCSGGCG-SSCGGCDSSCGSCGSGCRGCGPSCCAPVYCCKPVCCCVPACSCSSCGK
10 20 30 40 50
60 70 80 90 100 110
pF1KE6 SFCGFPSFSTGGTCDSSCCQPSCCETSCCQPSCYQTSSCGTGCGIGGGIGYGQEGSSGAV
:: . : :: : .:: .: . :::.: : :..::: .:
NP_005 RGCGSCGGSKGG-C-GSC---GCSQCSCCKPCC-----CSSGCG----------SSCCQC
60 70 80 90
120 130 140 150 160
pF1KE6 STRIRWCRPDCRVEGTCLPPCCVVSCTPPSCCQLHHAEASCCRP----SYCGQSCCRPVC
: :.: : . .: ::: : :::: .:::.: : ::.:::. :
NP_005 SC----CKPYCS-QCSCCKPCCSSSGRGSSCCQ-----SSCCKPCCSSSGCGSSCCQSSC
100 110 120 130 140
170
pF1KE6 C--CYCSEPTC
: : ::. :
NP_005 CKPC-CSQSRCCVPVCYQCKI
150 160
>>NP_001005922 (OMIM: 148022) keratin-associated protein (278 aa)
initn: 303 init1: 182 opt: 353 Z-score: 277.4 bits: 58.5 E(85289): 1e-08
Smith-Waterman score: 353; 35.3% identity (48.9% similar) in 190 aa overlap (1-177:1-177)
10 20 30 40 50
pF1KE6 MACCQTSF-CGFPSC----STSGTCGSSC--CQPSCCET-SSCQPRCCETSCCQPSCCQT
:.:: : :: :: : : :::.: : .: . ::: : . ::.: ::..
NP_001 MGCCGCSGGCG-SSCGGCGSGCGGCGSGCGGCGSGCGGSGSSC---CVPVCCCKPVCCRV
10 20 30 40 50
60 70 80 90 100 110
pF1KE6 SFCGFPSFSTGGTCDSSCCQPSCCETSC--CQPSCYQTSSCGTGCGIGGGIGYGQEGSSG
:. : . :: : :: . . : :: :. .: .::: . : :. : :..:. :
NP_001 PTCSCSSCGKGG-CGSSGGSKGGC-GSCGGCKGGC---GSCGGSKGGCGSCG-GSKGGCG
60 70 80 90 100 110
120 130 140 150 160
pF1KE6 AVSTRIRWCRPDCRVEGTCLPPCCV-VSCTPPSCCQLHHAEASCCRPSYCGQSCCRPVCC
. . : : : : ::: : : : :: . : : . ::. : :
NP_001 SCGGSKGGCGSGC---GGCGSSCCVPVCCCKPMCCCVPACSCSSCGKGGCGSCGCSKGAC
120 130 140 150 160
170
pF1KE6 CYC--SEPTC
: :. :
NP_001 GSCGGSKGGCGSCGGCKGGCGSCGGSKGGCGSGCGGCGSGCGVPVCCCSCSSCGSCAGSK
170 180 190 200 210 220
>--
initn: 422 init1: 182 opt: 257 Z-score: 208.4 bits: 45.7 E(85289): 7.2e-05
Smith-Waterman score: 257; 40.0% identity (53.3% similar) in 90 aa overlap (9-87:197-275)
10 20 30
pF1KE6 MACCQTSFCGFPSCSTSGTCGSSCCQPSCCETSS----
:: .: : :::.: : :: . :
NP_001 CGSCGGSKGGCGSCGGCKGGCGSCGGSKGGCG-SGC---GGCGSGCGVPVCCCSCSSCGS
170 180 190 200 210 220
40 50 60 70 80
pF1KE6 -------CQPRCCETSCCQPSCCQTSFCGFPSFSTGGTCDSSCCQPSCCETSCCQPSCYQ
: : . :::.: :: .: :: .. :.::::.: : ..::: : : :
NP_001 CAGSKGGCGSSCSQCSCCKPCCC-SSGCG------SSCCQSSCCKPCCSQSSCCVPVCCQ
230 240 250 260 270
90 100 110 120 130 140
pF1KE6 TSSCGTGCGIGGGIGYGQEGSSGAVSTRIRWCRPDCRVEGTCLPPCCVVSCTPPSCCQLH
NP_001 CKI
>>NP_787054 (OMIM: 600064) keratin-associated protein 11 (163 aa)
initn: 253 init1: 129 opt: 218 Z-score: 182.6 bits: 40.2 E(85289): 0.002
Smith-Waterman score: 228; 31.4% identity (51.1% similar) in 137 aa overlap (2-138:34-159)
10 20 30
pF1KE6 MACCQTSFCGFPSCSTSGTCGSSCCQPSCCE
: : ..: .:: .:. . :: .:::
NP_787 NCSTRNCSSRPIGGRCIVPVAQVTTTSTTDADCLGGIC-LPSSFQTGSWLLDHCQETCCE
10 20 30 40 50 60
40 50 60 70 80 90
pF1KE6 TSSCQPRCCETSCCQPSCCQTSFCGFPSFSTGGTCDSSCCQPSCCETSCCQPSCYQTSSC
..::: : . . : . ::.. :. . .. :... .: .: ::: .: :
NP_787 PTACQPTCYRRTSCVSNPCQVT-CSRQTTCISNPCSTTYSRPLTFVSSGCQPLGGISSVC
70 80 90 100 110 120
100 110 120 130 140 150
pF1KE6 GTGCGIGGGIGYGQEGSSGAVSTRIRWCRPDCRVEGTCLPPCCVVSCTPPSCCQLHHAEA
.:: : :.::: :.: : : : :: ::
NP_787 QP---VGGISTVCQ--PVGGVSTV---CQPACGVSRT-YQQSCVSSCRRTC
130 140 150 160
160 170
pF1KE6 SCCRPSYCGQSCCRPVCCCYCSEPTC
>>NP_853630 (OMIM: 608718) keratin-associated protein 13 (172 aa)
initn: 219 init1: 128 opt: 201 Z-score: 170.2 bits: 38.0 E(85289): 0.0097
Smith-Waterman score: 224; 29.1% identity (52.3% similar) in 151 aa overlap (7-138:24-166)
10 20 30 40
pF1KE6 MACCQTSFCGFPSCSTSGTCGSSCCQPSCCETSSCQPRCCETS
: ::: : .. . ... :.:: :. .: : :. .
NP_853 MSYNCCSGNFSSRSCGGYLHYPASSCGF-SYPSNQVYSTDLCSPSTCQLGSSLYRGCQQT
10 20 30 40 50
50 60 70 80
pF1KE6 CCQPSCCQTSFCGFPSFSTGGTCDSSCCQPS----C--CET----------SCCQPSCYQ
: .:. ::::. .. :..:: .: : :.: : :. :
NP_853 CWEPTSCQTSYV------ESSPCQTSCYRPRTSLLCSPCQTTYSGSLGFGSSSCRSLGYG
60 70 80 90 100 110
90 100 110 120 130 140
pF1KE6 TSSC-GTGCGIGG--GIGYGQEGSSGAVSTRIRWCRPDCRVEGTCLPPCCVVSCTPPSCC
. :: ..::: .: ..::: : ... . .::: . .: : .:
NP_853 SRSCYSVGCGSSGFRSLGYGGCGFP-SLGYGVGFCRPTYLASRSCQSSCYRPTCGSGFYY
120 130 140 150 160 170
150 160 170
pF1KE6 QLHHAEASCCRPSYCGQSCCRPVCCCYCSEPTC
177 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Nov 8 14:37:10 2016 done: Tue Nov 8 14:37:11 2016
Total Scan time: 3.130 Total Display time: -0.020
Function used was FASTA [36.3.4 Apr, 2011]