Result of FASTA (ccds) for
pFN21AE6573
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE6573, 201 aa
1>>>pF1KE6573 201 - 201 aa - 201 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 7.0599+/-0.000644; mu= 7.6031+/- 0.039
mean_var=111.8199+/-22.414, 0's: 0 Z-trim(114.9): 12 B-trim: 113 in 1/50
Lambda= 0.121287
statistics sampled from 15493 (15505) to 15493 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.799), E-opt: 0.2 (0.476), width: 16
Scan time: 1.600
The best scores are: opt bits E(32554)
CCDS1989.1 REEP1 gene_id:65055|Hs108|chr2 ( 201) 1335 242.9 9.8e-65
CCDS54374.1 REEP1 gene_id:65055|Hs108|chr2 ( 208) 1266 230.9 4.4e-61
CCDS54372.1 REEP1 gene_id:65055|Hs108|chr2 ( 174) 1112 203.9 4.8e-53
CCDS64259.1 REEP2 gene_id:51308|Hs108|chr5 ( 254) 895 166.0 1.8e-41
CCDS4205.1 REEP2 gene_id:51308|Hs108|chr5 ( 252) 866 160.9 6e-40
CCDS44411.1 REEP3 gene_id:221035|Hs108|chr10 ( 255) 852 158.5 3.3e-39
CCDS83258.1 REEP4 gene_id:80346|Hs108|chr8 ( 251) 828 154.3 6e-38
CCDS6024.1 REEP4 gene_id:80346|Hs108|chr8 ( 257) 828 154.3 6.2e-38
CCDS83257.1 REEP4 gene_id:80346|Hs108|chr8 ( 173) 738 138.4 2.4e-33
CCDS54373.1 REEP1 gene_id:65055|Hs108|chr2 ( 143) 415 81.9 2.1e-16
CCDS4109.2 REEP5 gene_id:7905|Hs108|chr5 ( 189) 329 66.9 9.1e-12
>>CCDS1989.1 REEP1 gene_id:65055|Hs108|chr2 (201 aa)
initn: 1335 init1: 1335 opt: 1335 Z-score: 1275.7 bits: 242.9 E(32554): 9.8e-65
Smith-Waterman score: 1335; 100.0% identity (100.0% similar) in 201 aa overlap (1-201:1-201)
10 20 30 40 50 60
pF1KE6 MVSWIISRLVVLIFGTLYPAYYSYKAVKSKDIKEYVKWMMYWIIFALFTTAETFTDIFLC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS19 MVSWIISRLVVLIFGTLYPAYYSYKAVKSKDIKEYVKWMMYWIIFALFTTAETFTDIFLC
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 WFPFYYELKIAFVAWLLSPYTKGSSLLYRKFVHPTLSSKEKEIDDCLVQAKDRSYDALVH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS19 WFPFYYELKIAFVAWLLSPYTKGSSLLYRKFVHPTLSSKEKEIDDCLVQAKDRSYDALVH
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 FGKRGLNVAATAAVMAASKGQGALSERLRSFSMQDLTTIRGDGAPAPSGPPPPGSGRASG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS19 FGKRGLNVAATAAVMAASKGQGALSERLRSFSMQDLTTIRGDGAPAPSGPPPPGSGRASG
130 140 150 160 170 180
190 200
pF1KE6 KHGQPKMSRSASESASSSGTA
:::::::::::::::::::::
CCDS19 KHGQPKMSRSASESASSSGTA
190 200
>>CCDS54374.1 REEP1 gene_id:65055|Hs108|chr2 (208 aa)
initn: 1266 init1: 1266 opt: 1266 Z-score: 1210.2 bits: 230.9 E(32554): 4.4e-61
Smith-Waterman score: 1266; 100.0% identity (100.0% similar) in 190 aa overlap (12-201:19-208)
10 20 30 40 50
pF1KE6 MVSWIISRLVVLIFGTLYPAYYSYKAVKSKDIKEYVKWMMYWIIFALFTTAET
::::::::::::::::::::::::::::::::::::::::::
CCDS54 MQKVLSNGQTEEVRSGSRLIFGTLYPAYYSYKAVKSKDIKEYVKWMMYWIIFALFTTAET
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE6 FTDIFLCWFPFYYELKIAFVAWLLSPYTKGSSLLYRKFVHPTLSSKEKEIDDCLVQAKDR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 FTDIFLCWFPFYYELKIAFVAWLLSPYTKGSSLLYRKFVHPTLSSKEKEIDDCLVQAKDR
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE6 SYDALVHFGKRGLNVAATAAVMAASKGQGALSERLRSFSMQDLTTIRGDGAPAPSGPPPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 SYDALVHFGKRGLNVAATAAVMAASKGQGALSERLRSFSMQDLTTIRGDGAPAPSGPPPP
130 140 150 160 170 180
180 190 200
pF1KE6 GSGRASGKHGQPKMSRSASESASSSGTA
::::::::::::::::::::::::::::
CCDS54 GSGRASGKHGQPKMSRSASESASSSGTA
190 200
>>CCDS54372.1 REEP1 gene_id:65055|Hs108|chr2 (174 aa)
initn: 1112 init1: 1112 opt: 1112 Z-score: 1065.7 bits: 203.9 E(32554): 4.8e-53
Smith-Waterman score: 1112; 100.0% identity (100.0% similar) in 166 aa overlap (36-201:9-174)
10 20 30 40 50 60
pF1KE6 ISRLVVLIFGTLYPAYYSYKAVKSKDIKEYVKWMMYWIIFALFTTAETFTDIFLCWFPFY
::::::::::::::::::::::::::::::
CCDS54 MDHLQAGGVKWMMYWIIFALFTTAETFTDIFLCWFPFY
10 20 30
70 80 90 100 110 120
pF1KE6 YELKIAFVAWLLSPYTKGSSLLYRKFVHPTLSSKEKEIDDCLVQAKDRSYDALVHFGKRG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 YELKIAFVAWLLSPYTKGSSLLYRKFVHPTLSSKEKEIDDCLVQAKDRSYDALVHFGKRG
40 50 60 70 80 90
130 140 150 160 170 180
pF1KE6 LNVAATAAVMAASKGQGALSERLRSFSMQDLTTIRGDGAPAPSGPPPPGSGRASGKHGQP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 LNVAATAAVMAASKGQGALSERLRSFSMQDLTTIRGDGAPAPSGPPPPGSGRASGKHGQP
100 110 120 130 140 150
190 200
pF1KE6 KMSRSASESASSSGTA
::::::::::::::::
CCDS54 KMSRSASESASSSGTA
160 170
>>CCDS64259.1 REEP2 gene_id:51308|Hs108|chr5 (254 aa)
initn: 910 init1: 875 opt: 895 Z-score: 858.0 bits: 166.0 E(32554): 1.8e-41
Smith-Waterman score: 895; 68.4% identity (83.7% similar) in 209 aa overlap (1-201:1-209)
10 20 30 40 50 60
pF1KE6 MVSWIISRLVVLIFGTLYPAYYSYKAVKSKDIKEYVKWMMYWIIFALFTTAETFTDIFLC
::::::::::::::::::::: ::::::.:..:::::::::::.::.::::::.::: :
CCDS64 MVSWIISRLVVLIFGTLYPAYSSYKAVKTKNVKEYVKWMMYWIVFAFFTTAETLTDIVLS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 WFPFYYELKIAFVAWLLSPYTKGSSLLYRKFVHPTLSSKEKEIDDCLVQAKDRSYDALVH
:::::.::::::: :::::::::::.:::::::::::.::::::. ..::.:.::.....
CCDS64 WFPFYFELKIAFVIWLLSPYTKGSSVLYRKFVHPTLSNKEKEIDEYITQARDKSYETMMR
70 80 90 100 110 120
130 140 150 160 170
pF1KE6 FGKRGLNVAATAAVMAASKGQGALSERLRSFSMQDLTTIRGDGA-PA--PSGP--PPPGS
::::::.::.::: ::.::::.:::.:::::::::: :: . : : :.: : :::
CCDS64 VGKRGLNLAANAAVTAAAKGQGVLSEKLRSFSMQDLTLIRDEDALPLQRPDGRLRPSPGS
130 140 150 160 170 180
180 190 200
pF1KE6 --GRASGKHGQPKMS-RSASESASSSGTA
.: .: ::... :.: :
CCDS64 LLDTIEDLGDDPALSLRSSTNPADSRTEASEDDMGDKAPKRAKPIKKAPKAEPLASKTLK
190 200 210 220 230 240
>>CCDS4205.1 REEP2 gene_id:51308|Hs108|chr5 (252 aa)
initn: 864 init1: 763 opt: 866 Z-score: 830.6 bits: 160.9 E(32554): 6e-40
Smith-Waterman score: 866; 67.5% identity (82.8% similar) in 209 aa overlap (1-201:1-207)
10 20 30 40 50 60
pF1KE6 MVSWIISRLVVLIFGTLYPAYYSYKAVKSKDIKEYVKWMMYWIIFALFTTAETFTDIFLC
::::::::::::::::::::: ::::::.:..:::::::::::.::.::::::.::: :
CCDS42 MVSWIISRLVVLIFGTLYPAYSSYKAVKTKNVKEYVKWMMYWIVFAFFTTAETLTDIVLS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 WFPFYYELKIAFVAWLLSPYTKGSSLLYRKFVHPTLSSKEKEIDDCLVQAKDRSYDALVH
:::::.::::::: :::::::::::.:::::::::::.::::::. ..::.:.::.....
CCDS42 WFPFYFELKIAFVIWLLSPYTKGSSVLYRKFVHPTLSNKEKEIDEYITQARDKSYETMMR
70 80 90 100 110 120
130 140 150 160 170
pF1KE6 FGKRGLNVAATAAVMAASKGQGALSERLRSFSMQDLTTIRGDGA-PA--PSGP--PPPGS
::::::.::.::: ::.:: .:::.:::::::::: :: . : : :.: : :::
CCDS42 VGKRGLNLAANAAVTAAAKG--VLSEKLRSFSMQDLTLIRDEDALPLQRPDGRLRPSPGS
130 140 150 160 170
180 190 200
pF1KE6 --GRASGKHGQPKMS-RSASESASSSGTA
.: .: ::... :.: :
CCDS42 LLDTIEDLGDDPALSLRSSTNPADSRTEASEDDMGDKAPKRAKPIKKAPKAEPLASKTLK
180 190 200 210 220 230
>>CCDS44411.1 REEP3 gene_id:221035|Hs108|chr10 (255 aa)
initn: 833 init1: 833 opt: 852 Z-score: 817.3 bits: 158.5 E(32554): 3.3e-39
Smith-Waterman score: 852; 66.5% identity (85.3% similar) in 191 aa overlap (1-191:1-188)
10 20 30 40 50 60
pF1KE6 MVSWIISRLVVLIFGTLYPAYYSYKAVKSKDIKEYVKWMMYWIIFALFTTAETFTDIFLC
::::.::: :::.:: ::::::::::::.:..::::.::::::.:::.:. :: .: .
CCDS44 MVSWMISRAVVLVFGMLYPAYYSYKAVKTKNVKEYVRWMMYWIVFALYTVIETVADQTVA
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 WFPFYYELKIAFVAWLLSPYTKGSSLLYRKFVHPTLSSKEKEIDDCLVQAKDRSYDALVH
:::.::::::::: :::::::::.::.::::.:: :::::.:::: .::::.:.:...:.
CCDS44 WFPLYYELKIAFVIWLLSPYTKGASLIYRKFLHPLLSSKEREIDDYIVQAKERGYETMVN
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 FGKRGLNVAATAAVMAASKGQGALSERLRSFSMQDLTTIRGDGAPAPSGPPPPGSGRASG
::..:::.:::::: :: :.:::..::::::::.:::::.:: : : : .
CCDS44 FGRQGLNLAATAAVTAAVKSQGAITERLRSFSMHDLTTIQGD---EPVGQRPYQPLPEAK
130 140 150 160 170
190 200
pF1KE6 KHGQPKMSRSASESASSSGTA
:...: :.::
CCDS44 KKSKPAPSESAGYGIPLKDGDEKTDEEAEGPYSDNEMLTHKGLRRSQSMKSVKTTKGRKE
180 190 200 210 220 230
>>CCDS83258.1 REEP4 gene_id:80346|Hs108|chr8 (251 aa)
initn: 822 init1: 822 opt: 828 Z-score: 794.7 bits: 154.3 E(32554): 6e-38
Smith-Waterman score: 828; 70.9% identity (87.8% similar) in 172 aa overlap (1-172:1-170)
10 20 30 40 50 60
pF1KE6 MVSWIISRLVVLIFGTLYPAYYSYKAVKSKDIKEYVKWMMYWIIFALFTTAETFTDIFLC
::::.: :::::.:: : ::: ::::::.:.:.:::.::::::.:::: .:: ::::.
CCDS83 MVSWMICRLVVLVFGMLCPAYASYKAVKTKNIREYVRWMMYWIVFALFMAAEIVTDIFIS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 WFPFYYELKIAFVAWLLSPYTKGSSLLYRKFVHPTLSSKEKEIDDCLVQAKDRSYDALVH
:::::::.:.::: :::::::::.::::::::::.:: .::::: .::::.:::....
CCDS83 WFPFYYEIKMAFVLWLLSPYTKGASLLYRKFVHPSLSRHEKEIDAYIVQAKERSYETVLS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 FGKRGLNVAATAAVMAASKGQGALSERLRSFSMQDLTTIRGDGAPAPSGPPPPGSGRASG
:::::::.::.:::.::.:.::::. :::::::::: .: . ::::. :
CCDS83 FGKRGLNIAASAAVQAATKSQGALAGRLRSFSMQDLRSI--SDAPAPAYHDPLYLEDQVS
130 140 150 160 170
190 200
pF1KE6 KHGQPKMSRSASESASSSGTA
CCDS83 HRRPPIGHLALPEGSDEEKDCALRRGQLGSAASAPFLPRALQGSRAIWRDLGLHIWPACT
180 190 200 210 220 230
>>CCDS6024.1 REEP4 gene_id:80346|Hs108|chr8 (257 aa)
initn: 841 init1: 822 opt: 828 Z-score: 794.6 bits: 154.3 E(32554): 6.2e-38
Smith-Waterman score: 828; 70.9% identity (87.8% similar) in 172 aa overlap (1-172:1-170)
10 20 30 40 50 60
pF1KE6 MVSWIISRLVVLIFGTLYPAYYSYKAVKSKDIKEYVKWMMYWIIFALFTTAETFTDIFLC
::::.: :::::.:: : ::: ::::::.:.:.:::.::::::.:::: .:: ::::.
CCDS60 MVSWMICRLVVLVFGMLCPAYASYKAVKTKNIREYVRWMMYWIVFALFMAAEIVTDIFIS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 WFPFYYELKIAFVAWLLSPYTKGSSLLYRKFVHPTLSSKEKEIDDCLVQAKDRSYDALVH
:::::::.:.::: :::::::::.::::::::::.:: .::::: .::::.:::....
CCDS60 WFPFYYEIKMAFVLWLLSPYTKGASLLYRKFVHPSLSRHEKEIDAYIVQAKERSYETVLS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 FGKRGLNVAATAAVMAASKGQGALSERLRSFSMQDLTTIRGDGAPAPSGPPPPGSGRASG
:::::::.::.:::.::.:.::::. :::::::::: .: . ::::. :
CCDS60 FGKRGLNIAASAAVQAATKSQGALAGRLRSFSMQDLRSI--SDAPAPAYHDPLYLEDQVS
130 140 150 160 170
190 200
pF1KE6 KHGQPKMSRSASESASSSGTA
CCDS60 HRRPPIGYRAGGLQDSDTEDECWSDTEAVPRAPARPREKPLIRSQSLRVVKRKPPVREGT
180 190 200 210 220 230
>>CCDS83257.1 REEP4 gene_id:80346|Hs108|chr8 (173 aa)
initn: 756 init1: 730 opt: 738 Z-score: 712.1 bits: 138.4 E(32554): 2.4e-33
Smith-Waterman score: 738; 64.7% identity (82.4% similar) in 170 aa overlap (1-170:1-169)
10 20 30 40 50 60
pF1KE6 MVSWIISRLVVLIFGTLYPAYYSYKAVKSKDIKEYVKWMMYWIIFALFTTAETFTDIFLC
::::.: :::::.:: : ::: ::::::.:.:.:::.::::::.:::: .:: ::::.
CCDS83 MVSWMICRLVVLVFGMLCPAYASYKAVKTKNIREYVRWMMYWIVFALFMAAEIVTDIFIS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 WFPFYYELKIAFVAWLLSPYTKGSSLLYRKFVHPTLSSKEKEIDDCLVQAKDRSYDALVH
:::::::.:.::: :::::::::.::::::::::.:: .::::: .::::.:::....
CCDS83 WFPFYYEIKMAFVLWLLSPYTKGASLLYRKFVHPSLSRHEKEIDAYIVQAKERSYETVLS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 FGKRGLNVAATAAVMAASKGQGALSERLRSFSMQDLTTIRGDGAPAPSGPPPPGSGRASG
:::::::.::.:::.::.:: : . : . :. .: . . : ::
CCDS83 FGKRGLNIAASAAVQAATKGTGPGACRTATPRMSVGQILRQSPGRQP-GPERSP
130 140 150 160 170
190 200
pF1KE6 KHGQPKMSRSASESASSSGTA
>>CCDS54373.1 REEP1 gene_id:65055|Hs108|chr2 (143 aa)
initn: 480 init1: 415 opt: 415 Z-score: 407.9 bits: 81.9 E(32554): 2.1e-16
Smith-Waterman score: 415; 100.0% identity (100.0% similar) in 61 aa overlap (1-61:1-61)
10 20 30 40 50 60
pF1KE6 MVSWIISRLVVLIFGTLYPAYYSYKAVKSKDIKEYVKWMMYWIIFALFTTAETFTDIFLC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 MVSWIISRLVVLIFGTLYPAYYSYKAVKSKDIKEYVKWMMYWIIFALFTTAETFTDIFLC
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 WFPFYYELKIAFVAWLLSPYTKGSSLLYRKFVHPTLSSKEKEIDDCLVQAKDRSYDALVH
:
CCDS54 WDRVPYRRDCGASACRTSPPSGETAPLLPRAPHHRGLGGPAANTASLRCPGVLLRALAAQ
70 80 90 100 110 120
201 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Nov 8 14:31:18 2016 done: Tue Nov 8 14:31:19 2016
Total Scan time: 1.600 Total Display time: -0.020
Function used was FASTA [36.3.4 Apr, 2011]