FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KE6559, 160 aa
  1>>>pF1KE6559 160 - 160 aa - 160 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 4.7581+/-0.000317; mu= 14.8961+/- 0.020
 mean_var=59.1130+/-12.058, 0's: 0 Z-trim(116.3): 47  B-trim: 1134 in 1/50
 Lambda= 0.166814
 statistics sampled from 27356 (27403) to 27356 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.711), E-opt: 0.2 (0.321), width:  16
 Scan time:  4.900

The best scores are:                                      opt bits E(85289)
NP_001162195 (OMIM: 616360) transmembrane protein  ( 436)  881 220.0 3.4e-57
NP_075069 (OMIM: 616360) transmembrane protein 135 ( 458)  871 217.6 1.9e-56
XP_016873629 (OMIM: 616360) PREDICTED: transmembra ( 374)  273 73.7 3.4e-13


>>NP_001162195 (OMIM: 616360) transmembrane protein 135   (436 aa)
 initn: 870 init1: 870 opt: 881  Z-score: 1147.7  bits: 220.0 E(85289): 3.4e-57
Smith-Waterman score: 881; 95.0% identity (96.5% similar) in 141 aa overlap (1-141:1-141)

               10        20        30        40        50        60
pF1KE6 MAALSKSIPHNCYEIGHTWHPSCRVSFLQITGGALEESLKIYAPLYLIAAILRKRKLDYY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MAALSKSIPHNCYEIGHTWHPSCRVSFLQITGGALEESLKIYAPLYLIAAILRKRKLDYY
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE6 LHKLLPEILQSASFLTANGALYMAFFCILRKILGKFYSWTPGFGAALPASYVAILIERKS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LHKLLPEILQSASFLTANGALYMAFFCILRKILGKFYSWTPGFGAALPASYVAILIERKS
               70        80        90       100       110       120

              130       140       150       160                    
pF1KE6 RRGLLTIYMANLMESHCLPQAGVISAPCSLCLPGSRDSPA                    
       ::::::::::::.   :.  :                                       
NP_001 RRGLLTIYMANLVLLFCITAAMYMFFFRCKDGLKGFTFSALRFIVGKEEIPTHSFSPEAA
              130       140       150       160       170       180

>>NP_075069 (OMIM: 616360) transmembrane protein 135 iso  (458 aa)
 initn: 869 init1: 869 opt: 871  Z-score: 1134.4  bits: 217.6 E(85289): 1.9e-56
Smith-Waterman score: 871; 94.4% identity (96.5% similar) in 143 aa overlap (1-143:1-142)

               10        20        30        40        50        60
pF1KE6 MAALSKSIPHNCYEIGHTWHPSCRVSFLQITGGALEESLKIYAPLYLIAAILRKRKLDYY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_075 MAALSKSIPHNCYEIGHTWHPSCRVSFLQITGGALEESLKIYAPLYLIAAILRKRKLDYY
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KE6 LHKLLPEILQSASFLTANGALYMAFFCILRKILGKFYSWTPGFGAALPASYVAILIERKS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_075 LHKLLPEILQSASFLTANGALYMAFFCILRKILGKFYSWTPGFGAALPASYVAILIERKS
               70        80        90       100       110       120

              130       140       150       160                    
pF1KE6 RRGLLTIYMANLMESHCLPQAGVISAPCSLCLPGSRDSPA                    
       ::::::::::::  .. : . ::                                     
NP_075 RRGLLTIYMANLA-TETLFRMGVARGTITTLRNGEVLLFCITAAMYMFFFRCKDGLKGFT
              130        140       150       160       170         

>>XP_016873629 (OMIM: 616360) PREDICTED: transmembrane p  (374 aa)
 initn: 271 init1: 271 opt: 273  Z-score: 357.9  bits: 73.7 E(85289): 3.4e-13
Smith-Waterman score: 273; 84.9% identity (90.6% similar) in 53 aa overlap (91-143:7-58)

               70        80        90       100       110       120
pF1KE6 LHKLLPEILQSASFLTANGALYMAFFCILRKILGKFYSWTPGFGAALPASYVAILIERKS
                                     ::::::::::::::::::::::::::::::
XP_016                         MLLCTWKILGKFYSWTPGFGAALPASYVAILIERKS
                                       10        20        30      

              130       140       150       160                    
pF1KE6 RRGLLTIYMANLMESHCLPQAGVISAPCSLCLPGSRDSPA                    
       ::::::::::::  .. : . ::                                     
XP_016 RRGLLTIYMANLA-TETLFRMGVARGTITTLRNGEVLLFCITAAMYMFFFRCKDGLKGFT
         40         50        60        70        80        90     




160 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Tue Nov  8 14:24:36 2016 done: Tue Nov  8 14:24:37 2016
 Total Scan time:  4.900 Total Display time: -0.020

Function used was FASTA [36.3.4 Apr, 2011]