Result of FASTA (ccds) for
pFN21AE6528
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE6528, 175 aa
1>>>pF1KE6528 175 - 175 aa - 175 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 4.9996+/-0.000654; mu= 14.0270+/- 0.039
mean_var=60.3044+/-11.877, 0's: 0 Z-trim(109.8): 18 B-trim: 0 in 0/52
Lambda= 0.165158
statistics sampled from 11116 (11130) to 11116 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.727), E-opt: 0.2 (0.342), width: 16
Scan time: 1.850
The best scores are: opt bits E(32554)
CCDS2380.1 CRYGB gene_id:1419|Hs108|chr2 ( 175) 1264 309.0 9.8e-85
CCDS2379.1 CRYGC gene_id:1420|Hs108|chr2 ( 174) 1019 250.6 3.6e-67
CCDS33367.1 CRYGA gene_id:1418|Hs108|chr2 ( 174) 974 239.9 6.2e-64
CCDS2378.1 CRYGD gene_id:1421|Hs108|chr2 ( 174) 951 234.4 2.8e-62
CCDS3275.1 CRYGS gene_id:1427|Hs108|chr3 ( 178) 733 182.4 1.2e-46
CCDS13831.1 CRYBB2 gene_id:1415|Hs108|chr22 ( 205) 395 101.9 2.4e-22
CCDS13830.1 CRYBB3 gene_id:1417|Hs108|chr22 ( 211) 384 99.3 1.5e-21
CCDS13840.1 CRYBB1 gene_id:1414|Hs108|chr22 ( 252) 369 95.8 2.1e-20
CCDS11249.1 CRYBA1 gene_id:1411|Hs108|chr17 ( 215) 347 90.5 6.9e-19
CCDS13841.1 CRYBA4 gene_id:1413|Hs108|chr22 ( 196) 322 84.5 4e-17
CCDS34506.1 AIM1 gene_id:202|Hs108|chr6 (1723) 322 85.1 2.4e-16
CCDS5926.1 CRYGN gene_id:155051|Hs108|chr7 ( 182) 310 81.7 2.7e-16
CCDS2429.1 CRYBA2 gene_id:1412|Hs108|chr2 ( 197) 310 81.7 2.9e-16
>>CCDS2380.1 CRYGB gene_id:1419|Hs108|chr2 (175 aa)
initn: 1264 init1: 1264 opt: 1264 Z-score: 1634.7 bits: 309.0 E(32554): 9.8e-85
Smith-Waterman score: 1264; 99.4% identity (100.0% similar) in 175 aa overlap (1-175:1-175)
10 20 30 40 50 60
pF1KE6 MGKITFYEDRAFQGRSYECTTDCPNLQPYFSRCNSIRVESGCWMIYERPNYQGHQYFLRR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS23 MGKITFYEDRAFQGRSYECTTDCPNLQPYFSRCNSIRVESGCWMIYERPNYQGHQYFLRR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 GEYPDYQQWMGLSDSIRSCCLIPPHSGAYRMKIYDRDELRGQMSELTDDCLSVQDRFHLT
::::::::::::::::::::::::::::::::::::::::::::::::::.:::::::::
CCDS23 GEYPDYQQWMGLSDSIRSCCLIPPHSGAYRMKIYDRDELRGQMSELTDDCISVQDRFHLT
70 80 90 100 110 120
130 140 150 160 170
pF1KE6 EIHSLNVLEGSWILYEMPNYRGRQYLLRPGEYRRFLDWGAPNAKVGSLRRVMDLY
:::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS23 EIHSLNVLEGSWILYEMPNYRGRQYLLRPGEYRRFLDWGAPNAKVGSLRRVMDLY
130 140 150 160 170
>>CCDS2379.1 CRYGC gene_id:1420|Hs108|chr2 (174 aa)
initn: 592 init1: 592 opt: 1019 Z-score: 1319.3 bits: 250.6 E(32554): 3.6e-67
Smith-Waterman score: 1019; 78.9% identity (93.1% similar) in 175 aa overlap (1-175:1-174)
10 20 30 40 50 60
pF1KE6 MGKITFYEDRAFQGRSYECTTDCPNLQPYFSRCNSIRVESGCWMIYERPNYQGHQYFLRR
:::::::::::::::::: :::::::::::::::::::::::::.::::::::.::.:::
CCDS23 MGKITFYEDRAFQGRSYETTTDCPNLQPYFSRCNSIRVESGCWMLYERPNYQGQQYLLRR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 GEYPDYQQWMGLSDSIRSCCLIPPHSGAYRMKIYDRDELRGQMSELTDDCLSVQDRFHLT
::::::::::::::::::::::: .. ..:...:.:.. .: : ::..:: :.::::::.
CCDS23 GEYPDYQQWMGLSDSIRSCCLIP-QTVSHRLRLYEREDHKGLMMELSEDCPSIQDRFHLS
70 80 90 100 110
130 140 150 160 170
pF1KE6 EIHSLNVLEGSWILYEMPNYRGRQYLLRPGEYRRFLDWGAPNAKVGSLRRVMDLY
::.::.:::: :.:::.:::::::::::: :::: :::: .::.::::::.:::
CCDS23 EIRSLHVLEGCWVLYELPNYRGRQYLLRPQEYRRCQDWGAMDAKAGSLRRVVDLY
120 130 140 150 160 170
>>CCDS33367.1 CRYGA gene_id:1418|Hs108|chr2 (174 aa)
initn: 561 init1: 534 opt: 974 Z-score: 1261.3 bits: 239.9 E(32554): 6.2e-64
Smith-Waterman score: 974; 73.7% identity (90.3% similar) in 175 aa overlap (1-175:1-174)
10 20 30 40 50 60
pF1KE6 MGKITFYEDRAFQGRSYECTTDCPNLQPYFSRCNSIRVESGCWMIYERPNYQGHQYFLRR
:::::::::: :::: :.: .:::::. ::::::::::.:::::.:::::::::::::::
CCDS33 MGKITFYEDRDFQGRCYNCISDCPNLRVYFSRCNSIRVDSGCWMLYERPNYQGHQYFLRR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 GEYPDYQQWMGLSDSIRSCCLIPPHSGAYRMKIYDRDELRGQMSELTDDCLSVQDRFHLT
:.:::::.:::::::..:: .:: :........:.::. :: :::::::: : . :.:
CCDS33 GKYPDYQHWMGLSDSVQSCRIIP-HTSSHKLRLYERDDYRGLMSELTDDCACVPELFRLP
70 80 90 100 110
130 140 150 160 170
pF1KE6 EIHSLNVLEGSWILYEMPNYRGRQYLLRPGEYRRFLDWGAPNAKVGSLRRVMDLY
::.::.:::: :.:::::::::::::::::.:::. :::. .::::::::: :::
CCDS33 EIYSLHVLEGCWVLYEMPNYRGRQYLLRPGDYRRYHDWGGADAKVGSLRRVTDLY
120 130 140 150 160 170
>>CCDS2378.1 CRYGD gene_id:1421|Hs108|chr2 (174 aa)
initn: 987 init1: 500 opt: 951 Z-score: 1231.7 bits: 234.4 E(32554): 2.8e-62
Smith-Waterman score: 951; 72.4% identity (91.4% similar) in 174 aa overlap (1-174:1-173)
10 20 30 40 50 60
pF1KE6 MGKITFYEDRAFQGRSYECTTDCPNLQPYFSRCNSIRVESGCWMIYERPNYQGHQYFLRR
:::::.::::.:::: :::..: ::::::.::::: ::.:::::.::.:::.: ::::::
CCDS23 MGKITLYEDRGFQGRHYECSSDHPNLQPYLSRCNSARVDSGCWMLYEQPNYSGLQYFLRR
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 GEYPDYQQWMGLSDSIRSCCLIPPHSGAYRMKIYDRDELRGQMSELTDDCLSVQDRFHLT
:.: :.:::::::::.::: ::: :::..:...:.:.. :::: :.:.:: .::::...
CCDS23 GDYADHQQWMGLSDSVRSCRLIP-HSGSHRIRLYEREDYRGQMIEFTEDCSCLQDRFRFN
70 80 90 100 110
130 140 150 160 170
pF1KE6 EIHSLNVLEGSWILYEMPNYRGRQYLLRPGEYRRFLDWGAPNAKVGSLRRVMDLY
::::::::::::.:::. ::::::::: ::.:::. :::: ::.:::::::.:.
CCDS23 EIHSLNVLEGSWVLYELSNYRGRQYLLMPGDYRRYQDWGATNARVGSLRRVIDFS
120 130 140 150 160 170
>>CCDS3275.1 CRYGS gene_id:1427|Hs108|chr3 (178 aa)
initn: 692 init1: 388 opt: 733 Z-score: 950.9 bits: 182.4 E(32554): 1.2e-46
Smith-Waterman score: 733; 54.7% identity (80.2% similar) in 172 aa overlap (3-173:7-178)
10 20 30 40 50
pF1KE6 MGKITFYEDRAFQGRSYECTTDCPNLQPYFSRCNSIRVESGCWMIYERPNYQGHQY
:::::::. :::: :.: :: ... :.::::::.::.: : .:::::. :..:
CCDS32 MSKTGTKITFYEDKNFQGRRYDCDCDCADFHTYLSRCNSIKVEGGTWAVYERPNFAGYMY
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE6 FLRRGEYPDYQQWMGLSDSIRSCCLIP-PHSGAYRMKIYDRDELRGQMSELTDDCLSVQD
.: .::::.::.::::.: . :: . : .: :...:... .. ::: : :.:: :...
CCDS32 ILPQGEYPEYQRWMGLNDRLSSCRAVHLPSGGQYKIQIFEKGDFSGQMYETTEDCPSIME
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE6 RFHLTEIHSLNVLEGSWILYEMPNYRGRQYLLRPGEYRRFLDWGAPNAKVGSLRRVMDLY
.::. :::: .:::: ::.::.:::::::::: :::. .:::: . : :.::...
CCDS32 QFHMREIHSCKVLEGVWIFYELPNYRGRQYLLDKKEYRKPIDWGAASPAVQSFRRIVE
130 140 150 160 170
>>CCDS13831.1 CRYBB2 gene_id:1415|Hs108|chr22 (205 aa)
initn: 417 init1: 192 opt: 395 Z-score: 514.7 bits: 101.9 E(32554): 2.4e-22
Smith-Waterman score: 395; 34.7% identity (67.0% similar) in 176 aa overlap (3-174:18-193)
10 20 30 40
pF1KE6 MGKITFYEDRAFQGRSYECTTDCPNLQPY-FSRCNSIRVESGCWM
:: ..:.. :::.:.: . ::::. . .:. :..: :.
CCDS13 MASDHQTQAGKPQSLNPKIIIFEQENFQGHSHELNGPCPNLKETGVEKAGSVLVQAGPWV
10 20 30 40 50 60
50 60 70 80 90 100
pF1KE6 IYERPNYQGHQYFLRRGEYPDYQQWMGL--SDSIRSCCLIPPHSGAYRMKIYDRDELRGQ
::. : .:.:. ...:::: ...: . .::. : : : ... .:. .. :.
CCDS13 GYEQANCKGEQFVFEKGEYPRWDSWTSSRRTDSLSSLRPIKVDSQEHKIILYENPNFTGK
70 80 90 100 110 120
110 120 130 140 150 160
pF1KE6 MSELTDDCL-SVQDRFHLTEIHSLNVLEGSWILYEMPNYRGRQYLLRPGEYRRFLDWGAP
:. :: . : . . . .. :. : :.:. :..:.::: ::::. :.:. :.:::
CCDS13 KMEIIDDDVPSFHAHGYQEKVSSVRVQSGTWVGYQYPGYRGLQYLLEKGDYKDSSDFGAP
130 140 150 160 170 180
170
pF1KE6 NAKVGSLRRVMDLY
. .: :.::. :.
CCDS13 HPQVQSVRRIRDMQWHQRGAFHPSN
190 200
>>CCDS13830.1 CRYBB3 gene_id:1417|Hs108|chr22 (211 aa)
initn: 359 init1: 184 opt: 384 Z-score: 500.3 bits: 99.3 E(32554): 1.5e-21
Smith-Waterman score: 384; 32.0% identity (66.9% similar) in 178 aa overlap (3-173:25-199)
10 20 30
pF1KE6 MGKITFYEDRAFQGRSYECTTDCPNL-QPYFSRCNSIR
:. .:: . :::. : ...::.: . . . .::.
CCDS13 MAEQHGAPEQAAAGKSHGDLGGSYKVILYELENFQGKRCELSAECPSLTDSLLEKVGSIQ
10 20 30 40 50 60
40 50 60 70 80 90
pF1KE6 VESGCWMIYERPNYQGHQYFLRRGEYPDYQQWMGLSDS-----IRSCCLIPPHSGAYRMK
:::: :. .: ..:.:. :..:.:: .. : . :: .: . :: ....
CCDS13 VESGPWLAFESRAFRGEQFVLEKGDYPRWDAWSNSRDSDSLLSLRPLNIDSPH---HKLH
70 80 90 100 110
100 110 120 130 140 150
pF1KE6 IYDRDELRGQMSELTDDCL-SVQDRFHLTEIHSLNVLEGSWILYEMPNYRGRQYLLRPGE
... . :. :..:: . :. . .. :. ...:.:. ::.:.::::::... ::
CCDS13 LFENPAFSGRKMEIVDDDVPSLWAHGFQDRVASVRAINGTWVGYEFPGYRGRQYVFERGE
120 130 140 150 160 170
160 170
pF1KE6 YRRFLDWGAPNAKVGSLRRVMDLY
::.. .: : . .. :.::. :
CCDS13 YRHWNEWDASQPQLQSVRRIRDQKWHKRGRFPSS
180 190 200 210
>>CCDS13840.1 CRYBB1 gene_id:1414|Hs108|chr22 (252 aa)
initn: 356 init1: 188 opt: 369 Z-score: 479.9 bits: 95.8 E(32554): 2.1e-20
Smith-Waterman score: 369; 33.1% identity (65.7% similar) in 175 aa overlap (3-173:60-234)
10 20 30
pF1KE6 MGKITFYEDRAFQGRSYECTTDCPNLQPY-FS
... .: . :::: : . .: :: :.
CCDS13 GTSPSPGTTLAPTTVPITSAKAAELPPGNYRLVVFELENFQGRRAEFSGECSNLADRGFD
30 40 50 60 70 80
40 50 60 70 80
pF1KE6 RCNSIRVESGCWMIYERPNYQGHQYFLRRGEYPDYQQWMGL--SDSIRSCCLIPPHSGAY
: :: : .: :. .:. :..:....:..:::: .. : . :: . : : . .
CCDS13 RVRSIIVSAGPWVAFEQSNFRGEMFILEKGEYPRWNTWSSSYRSDRLMSFRPIKMDAQEH
90 100 110 120 130 140
90 100 110 120 130 140
pF1KE6 RMKIYDRDELRGQMSELT-DDCLSVQDRFHLTEIHSLNVLEGSWILYEMPNYRGRQYLLR
...... ...:. :. :: :. .. :..: :.:. :..:.::: ::::.
CCDS13 KISLFEGANFKGNTIEIQGDDAPSLWVYGFSDRVGSVKVSSGTWVGYQYPGYRGYQYLLE
150 160 170 180 190 200
150 160 170
pF1KE6 PGEYRRFLDWGAPNAKVGSLRRVMDLY
::..:.. .::: . .. ::::. :
CCDS13 PGDFRHWNEWGAFQPQMQSLRRLRDKQWHLEGSFPVLATEPPK
210 220 230 240 250
>>CCDS11249.1 CRYBA1 gene_id:1411|Hs108|chr17 (215 aa)
initn: 243 init1: 135 opt: 347 Z-score: 452.6 bits: 90.5 E(32554): 6.9e-19
Smith-Waterman score: 391; 33.7% identity (67.4% similar) in 184 aa overlap (3-171:32-213)
10 20 30
pF1KE6 MGKITFYEDRAFQGRSYECTTDCPNLQPY-FS
:::.:... :::. .: :..:::.. :.
CCDS11 ETQAEQQELETLPTTKMAQTNPTPGSLGPWKITIYDQENFQGKRMEFTSSCPNVSERSFD
10 20 30 40 50 60
40 50 60 70 80
pF1KE6 RCNSIRVESGCWMIYERPNYQGHQYFLRRGEYPDYQQWMGLSD-------SIRSCCLIPP
:..:::: :. ::. .. :.:..:.::::: .. : : . :.: :
CCDS11 NVRSLKVESGAWIGYEHTSFCGQQFILERGEYPRWDAWSGSNAYHIERLMSFRPIC--SA
70 80 90 100 110
90 100 110 120 130 140
pF1KE6 HSGAYRMKIYDRDELRGQMSELTDDCLSVQDR-FHLTEIHSLNVLEGSWILYEMPNYRGR
. .: :...... :.. :..:: :.: . .:. :... :.:. :..:.:::
CCDS11 NHKESKMTIFEKENFIGRQWEISDDYPSLQAMGWFNNEVGSMKIQSGAWVCYQYPGYRGY
120 130 140 150 160 170
150 160 170
pF1KE6 QYLLR----PGEYRRFLDWG--APNAKVGSLRRVMDLY
::.:. :.:... .:: : .... :.::.
CCDS11 QYILECDHHGGDYKHWREWGSHAQTSQIQSIRRIQQ
180 190 200 210
>>CCDS13841.1 CRYBA4 gene_id:1413|Hs108|chr22 (196 aa)
initn: 339 init1: 149 opt: 322 Z-score: 421.0 bits: 84.5 E(32554): 4e-17
Smith-Waterman score: 382; 34.6% identity (68.1% similar) in 182 aa overlap (3-171:13-194)
10 20 30 40
pF1KE6 MGKITFYEDRAFQGRSYECTTDCPN-LQPYFSRCNSIRVESGCWMIYERP
:.. ... .:::: .: :..::. :. : :..: :: :. .:.
CCDS13 MTLQCTKSAGPWKMVVWDEDGFQGRRHEFTAECPSVLELGFETVRSLKVLSGAWVGFEHA
10 20 30 40 50 60
50 60 70 80 90 100
pF1KE6 NYQGHQYFLRRGEYPDYQQWMGLS--DSIRSCCLIPPHSGAYR---MKIYDRDELRGQMS
..::.::.:.:::::... : : . . : . : . .: . :...... :. .
CCDS13 GFQGQQYILERGEYPSWDAWGGNTAYPAERLTSFRPAACANHRDSRLTIFEQENFLGKKG
70 80 90 100 110 120
110 120 130 140 150
pF1KE6 ELTDDCLSVQDR-FHLTEIHSLNVLEGSWILYEMPNYRGRQYLLR----PGEYRRFLDWG
::.:: :.: .. .:. :..: :.:. ..:.::: ::.:. :.:..: .::
CCDS13 ELSDDYPSLQAMGWEGNEVGSFHVHSGAWVCSQFPGYRGFQYVLECDHHSGDYKHFREWG
130 140 150 160 170 180
160 170
pF1KE6 --APNAKVGSLRRVMDLY
::. .: :.::.
CCDS13 SHAPTFQVQSIRRIQQ
190
175 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Nov 8 14:07:47 2016 done: Tue Nov 8 14:07:47 2016
Total Scan time: 1.850 Total Display time: -0.020
Function used was FASTA [36.3.4 Apr, 2011]