Result of FASTA (omim) for
pFN21AE6523
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE6523, 94 aa
1>>>pF1KE6523 94 - 94 aa - 94 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 7.7459+/-0.000231; mu= 1.3986+/- 0.015
mean_var=179.9128+/-35.672, 0's: 0 Z-trim(128.7): 23 B-trim: 56 in 1/56
Lambda= 0.095619
statistics sampled from 60000 (61239) to 61582 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.927), E-opt: 0.2 (0.722), width: 16
Scan time: 4.520
The best scores are: opt bits E(85289)
NP_848521 (OMIM: 612615) late cornified envelope p ( 94) 760 114.2 3.1e-26
NP_115952 (OMIM: 612616) late cornified envelope p ( 92) 620 94.9 2e-20
XP_011507786 (OMIM: 612617) PREDICTED: late cornif ( 92) 606 93.0 7.7e-20
NP_848522 (OMIM: 612617) late cornified envelope p ( 92) 606 93.0 7.7e-20
NP_848520 (OMIM: 612614) late cornified envelope p ( 95) 568 87.7 3e-18
NP_848518 (OMIM: 612613) late cornified envelope p ( 89) 546 84.7 2.3e-17
NP_848133 (OMIM: 612618) late cornified envelope p ( 99) 458 72.6 1.1e-13
NP_848125 (OMIM: 612603) late cornified envelope p ( 110) 405 65.3 2e-11
NP_848515 (OMIM: 612609) late cornified envelope p ( 106) 371 60.6 4.9e-10
NP_848525 (OMIM: 612619) late cornified envelope p ( 118) 360 59.1 1.5e-09
NP_001263260 (OMIM: 612605) late cornified envelop ( 88) 328 54.6 2.6e-08
XP_011507023 (OMIM: 612618) PREDICTED: late cornif ( 175) 326 54.6 5.3e-08
NP_848128 (OMIM: 612605) late cornified envelope p ( 118) 313 52.6 1.4e-07
NP_848516 (OMIM: 612611) late cornified envelope p ( 110) 304 51.4 3.1e-07
NP_848517 (OMIM: 612612) late cornified envelope p ( 110) 303 51.2 3.4e-07
NP_848130 (OMIM: 612607) late cornified envelope p ( 118) 302 51.1 3.9e-07
NP_055172 (OMIM: 612610) late cornified envelope p ( 110) 299 50.7 4.9e-07
NP_848131 (OMIM: 612608) late cornified envelope p ( 118) 297 50.4 6.3e-07
NP_848129 (OMIM: 612606) late cornified envelope p ( 114) 285 48.8 1.9e-06
NP_848126 (OMIM: 612604) late cornified envelope p ( 118) 284 48.6 2.2e-06
>>NP_848521 (OMIM: 612615) late cornified envelope prote (94 aa)
initn: 760 init1: 760 opt: 760 Z-score: 591.9 bits: 114.2 E(85289): 3.1e-26
Smith-Waterman score: 760; 100.0% identity (100.0% similar) in 94 aa overlap (1-94:1-94)
10 20 30 40 50 60
pF1KE6 MSCQQNQQQCQPPPSCPSPKCPPKSPAQCLPPPSSDCALSSGGCGPSSESGCCLSHHRHF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_848 MSCQQNQQQCQPPPSCPSPKCPPKSPAQCLPPPSSDCALSSGGCGPSSESGCCLSHHRHF
10 20 30 40 50 60
70 80 90
pF1KE6 RSHQCRRQRSNSCDRGSGQQGGGSCRGHGSGGCC
::::::::::::::::::::::::::::::::::
NP_848 RSHQCRRQRSNSCDRGSGQQGGGSCRGHGSGGCC
70 80 90
>>NP_115952 (OMIM: 612616) late cornified envelope prote (92 aa)
initn: 469 init1: 407 opt: 620 Z-score: 487.6 bits: 94.9 E(85289): 2e-20
Smith-Waterman score: 620; 84.0% identity (89.4% similar) in 94 aa overlap (1-94:1-92)
10 20 30 40 50 60
pF1KE6 MSCQQNQQQCQPPPSCPSPKCPPKSPAQCLPPPSSDCALSSGGCGPSSESGCCLSHHRHF
::::::::::::::.:::::::::::.::::: :: :: ::::::::::.:: :.:::
NP_115 MSCQQNQQQCQPPPKCPSPKCPPKSPVQCLPPASSGCAPSSGGCGPSSEGGCFLNHHR--
10 20 30 40 50
70 80 90
pF1KE6 RSHQCRRQRSNSCDRGSGQQGGGSCRGHGSGGCC
: :.::::: :::::::::::::: ::::::::
NP_115 RHHRCRRQRPNSCDRGSGQQGGGSGCGHGSGGCC
60 70 80 90
>>XP_011507786 (OMIM: 612617) PREDICTED: late cornified (92 aa)
initn: 440 init1: 398 opt: 606 Z-score: 477.2 bits: 93.0 E(85289): 7.7e-20
Smith-Waterman score: 606; 81.9% identity (89.4% similar) in 94 aa overlap (1-94:1-92)
10 20 30 40 50 60
pF1KE6 MSCQQNQQQCQPPPSCPSPKCPPKSPAQCLPPPSSDCALSSGGCGPSSESGCCLSHHRHF
:::::::.::::::.:::::::::.:.::::: :: :: ::::::::::.:: :.:::
XP_011 MSCQQNQKQCQPPPKCPSPKCPPKNPVQCLPPASSGCAPSSGGCGPSSEGGCFLNHHR--
10 20 30 40 50
70 80 90
pF1KE6 RSHQCRRQRSNSCDRGSGQQGGGSCRGHGSGGCC
: :.:::::::::::::::::::: :::::::
XP_011 RHHRCRRQRSNSCDRGSGQQGGGSGCCHGSGGCC
60 70 80 90
>>NP_848522 (OMIM: 612617) late cornified envelope prote (92 aa)
initn: 440 init1: 398 opt: 606 Z-score: 477.2 bits: 93.0 E(85289): 7.7e-20
Smith-Waterman score: 606; 81.9% identity (89.4% similar) in 94 aa overlap (1-94:1-92)
10 20 30 40 50 60
pF1KE6 MSCQQNQQQCQPPPSCPSPKCPPKSPAQCLPPPSSDCALSSGGCGPSSESGCCLSHHRHF
:::::::.::::::.:::::::::.:.::::: :: :: ::::::::::.:: :.:::
NP_848 MSCQQNQKQCQPPPKCPSPKCPPKNPVQCLPPASSGCAPSSGGCGPSSEGGCFLNHHR--
10 20 30 40 50
70 80 90
pF1KE6 RSHQCRRQRSNSCDRGSGQQGGGSCRGHGSGGCC
: :.:::::::::::::::::::: :::::::
NP_848 RHHRCRRQRSNSCDRGSGQQGGGSGCCHGSGGCC
60 70 80 90
>>NP_848520 (OMIM: 612614) late cornified envelope prote (95 aa)
initn: 376 init1: 305 opt: 568 Z-score: 448.7 bits: 87.7 E(85289): 3e-18
Smith-Waterman score: 568; 78.9% identity (84.2% similar) in 95 aa overlap (1-94:1-95)
10 20 30 40 50
pF1KE6 MSCQQNQQQCQPPPSCPSPKCPPKSPAQCLPPPSSDCALSSGGCG-PSSESGCCLSHHRH
:::::::::::: :.:::::::::: :::::: :: :: : :: ::::.::::::::
NP_848 MSCQQNQQQCQPLPKCPSPKCPPKSSAQCLPPASSCCAPRPGCCGGPSSEGGCCLSHHRC
10 20 30 40 50 60
60 70 80 90
pF1KE6 FRSHQCRRQRSNSCDRGSGQQGGGSCRGHGSGGCC
:::.:::: ::::::::::: :.: :.::::::
NP_848 CRSHRCRRQSSNSCDRGSGQQDGASDCGYGSGGCC
70 80 90
>>NP_848518 (OMIM: 612613) late cornified envelope prote (89 aa)
initn: 468 init1: 468 opt: 546 Z-score: 432.6 bits: 84.7 E(85289): 2.3e-17
Smith-Waterman score: 546; 77.7% identity (84.0% similar) in 94 aa overlap (1-94:1-89)
10 20 30 40 50 60
pF1KE6 MSCQQNQQQCQPPPSCPSPKCPPKSPAQCLPPPSSDCALSSGGCGPSSESGCCLSHHRHF
:::::::::::::: ::: ::::::::: ::.:: :::::::::: .:::::::
NP_848 MSCQQNQQQCQPPP-----KCPAKSPAQCLPPASSSCAPSSGGCGPSSERSCCLSHHRCR
10 20 30 40 50
70 80 90
pF1KE6 RSHQCRRQRSNSCDRGSGQQGGGSCRGHGSGGCC
:::.:: : :::::::::::::.: ::.:.:::
NP_848 RSHRCRCQSSNSCDRGSGQQGGSSSCGHSSAGCC
60 70 80
>>NP_848133 (OMIM: 612618) late cornified envelope prote (99 aa)
initn: 592 init1: 201 opt: 458 Z-score: 366.4 bits: 72.6 E(85289): 1.1e-13
Smith-Waterman score: 458; 66.0% identity (75.7% similar) in 103 aa overlap (1-94:1-99)
10 20 30 40 50
pF1KE6 MSCQQNQQQCQPPPSCPSPKCPPKSPAQCL---PPP-SSDCALSSGGCGP-SSESG-CCL
::::::::::::::.:: :: ::: :..: ::: :: :. :::::: :::.: :::
NP_848 MSCQQNQQQCQPPPKCPIPKYPPKCPSKCASSCPPPISSCCGSSSGGCGCCSSEGGGCCL
10 20 30 40 50 60
60 70 80 90
pF1KE6 SHHRHFRSHQCRRQRSNSC-DRGSGQQGGGS--CRGHGSGGCC
::::: ::: :.: .:..: :::::.::: : : ::::
NP_848 SHHRHHRSH-CHRPKSSNCYGSGSGQQSGGSGCCSG---GGCC
70 80 90
>>NP_848125 (OMIM: 612603) late cornified envelope prote (110 aa)
initn: 368 init1: 182 opt: 405 Z-score: 326.3 bits: 65.3 E(85289): 2e-11
Smith-Waterman score: 405; 53.5% identity (65.8% similar) in 114 aa overlap (1-94:1-110)
10 20 30 40 50
pF1KE6 MSCQQNQQQCQPPPSC--------PSPKCPPKSPAQCLPPPSSDCALSSGGCGPSSESG-
:::::.::::::::.: :.:::::: : .: :: :: :..::::: :: .:
NP_848 MSCQQSQQQCQPPPKCTPKCPPKCPTPKCPPKCPPKC-PPVSSCCSVSSGGCCGSSSGGG
10 20 30 40 50
60 70 80 90
pF1KE6 -------CCLSHHRHFRSHQCRRQRSNSCDRGSGQQGGGSC----RGHGSGGCC
:::::::. :::. : : :. :.. :: :.:: :. :::::
NP_848 CSSGGGGCCLSHHRRHRSHRHRLQSSGCCSQPSG---GSSCCGGDSGQHSGGCC
60 70 80 90 100 110
>>NP_848515 (OMIM: 612609) late cornified envelope prote (106 aa)
initn: 464 init1: 177 opt: 371 Z-score: 301.2 bits: 60.6 E(85289): 4.9e-10
Smith-Waterman score: 375; 51.4% identity (63.1% similar) in 111 aa overlap (1-94:1-106)
10 20 30 40
pF1KE6 MSCQQNQQQCQPPPSCPSPKCPPKSPAQC-------LPPPSSDC---------ALSSGGC
::::::::::::::.:: :::::: : .: ::: :.: . :::::
NP_848 MSCQQNQQQCQPPPKCP-PKCPPKCPPKCRPQCPAPCPPPVSSCCGPSSGGCCGSSSGGC
10 20 30 40 50
50 60 70 80 90
pF1KE6 GPSSESGCCLSHHRHFRSHQCRRQRSNSCD-RGSGQQGGGSCRGHGSGGCC
:. .:::::::: :. :.: . :. . :: :.: : :.:: ::
NP_848 CSSGGGGCCLSHHRPRLFHRHRHQSPDCCECEPSG--GSGCC--HSSGDCC
60 70 80 90 100
>>NP_848525 (OMIM: 612619) late cornified envelope prote (118 aa)
initn: 396 init1: 302 opt: 360 Z-score: 292.3 bits: 59.1 E(85289): 1.5e-09
Smith-Waterman score: 415; 55.9% identity (67.6% similar) in 111 aa overlap (1-94:1-111)
10 20 30 40
pF1KE6 MSCQQNQQQCQPPPSC-PS----------PKCPPKSPAQC---LPPP-SSDCALSSGGCG
:::::.::::::::.: :. :::::: : :: ::: :: :. :::::
NP_848 MSCQQSQQQCQPPPKCTPKCPPKCTPKCPPKCPPKCPPQCSAPCPPPVSSCCGSSSGGCC
10 20 30 40 50 60
50 60 70 80 90
pF1KE6 PSSESGCCLSHHRHFRSHQCRRQRSNSCDRGSGQQGGGS--CRGHGSGGCC
: .:::::::: .: . : : :. : :::::.::: :.. :..:::
NP_848 SSEGGGCCLSHHRPRQSLRRRPQSSSCCGSGSGQQSGGSSCCHSSGGSGCCHSSGGCC
70 80 90 100 110
94 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Nov 8 14:04:53 2016 done: Tue Nov 8 14:04:54 2016
Total Scan time: 4.520 Total Display time: -0.030
Function used was FASTA [36.3.4 Apr, 2011]