Result of FASTA (omim) for
pFN21AE6511
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE6511, 175 aa
1>>>pF1KE6511 175 - 175 aa - 175 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.0394+/-0.000319; mu= 14.7747+/- 0.020
mean_var=69.3004+/-14.316, 0's: 0 Z-trim(116.7): 43 B-trim: 0 in 0/54
Lambda= 0.154066
statistics sampled from 28103 (28146) to 28103 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.719), E-opt: 0.2 (0.33), width: 16
Scan time: 4.230
The best scores are: opt bits E(85289)
XP_011525651 (OMIM: 611951,614175) PREDICTED: B9 d ( 175) 1261 288.5 3.6e-78
NP_085055 (OMIM: 611951,614175) B9 domain-containi ( 175) 1261 288.5 3.6e-78
XP_011525652 (OMIM: 611951,614175) PREDICTED: B9 d ( 122) 903 208.9 2.4e-54
NP_056496 (OMIM: 614144,614209,617120) B9 domain-c ( 204) 281 70.8 1.5e-12
NP_001317078 (OMIM: 614144,614209,617120) B9 domai ( 161) 264 66.9 1.7e-11
NP_001308147 (OMIM: 614144,614209,617120) B9 domai ( 166) 264 66.9 1.8e-11
NP_001308144 (OMIM: 614144,614209,617120) B9 domai ( 183) 264 67.0 1.9e-11
NP_001308146 (OMIM: 614144,614209,617120) B9 domai ( 186) 264 67.0 1.9e-11
NP_001308143 (OMIM: 614144,614209,617120) B9 domai ( 187) 264 67.0 1.9e-11
XP_005256667 (OMIM: 614144,614209,617120) PREDICTE ( 142) 247 63.1 2.1e-10
XP_016879941 (OMIM: 614144,614209,617120) PREDICTE ( 153) 247 63.1 2.3e-10
NP_001308145 (OMIM: 614144,614209,617120) B9 domai ( 153) 247 63.1 2.3e-10
NP_001308148 (OMIM: 614144,614209,617120) B9 domai ( 155) 247 63.1 2.3e-10
NP_001308197 (OMIM: 249000,609883,615990,617121) M ( 356) 198 52.5 8.3e-07
XP_016880294 (OMIM: 249000,609883,615990,617121) P ( 416) 198 52.6 9.4e-07
NP_001159399 (OMIM: 249000,609883,615990,617121) M ( 549) 198 52.6 1.2e-06
NP_060247 (OMIM: 249000,609883,615990,617121) Meck ( 559) 198 52.6 1.2e-06
XP_011523260 (OMIM: 249000,609883,615990,617121) P ( 562) 198 52.7 1.2e-06
XP_006722028 (OMIM: 249000,609883,615990,617121) P ( 358) 192 51.2 2.1e-06
XP_005257542 (OMIM: 249000,609883,615990,617121) P ( 418) 192 51.2 2.4e-06
NP_001308198 (OMIM: 249000,609883,615990,617121) M ( 561) 192 51.3 3e-06
XP_011523259 (OMIM: 249000,609883,615990,617121) P ( 564) 192 51.3 3e-06
>>XP_011525651 (OMIM: 611951,614175) PREDICTED: B9 domai (175 aa)
initn: 1261 init1: 1261 opt: 1261 Z-score: 1524.4 bits: 288.5 E(85289): 3.6e-78
Smith-Waterman score: 1261; 99.4% identity (100.0% similar) in 175 aa overlap (1-175:1-175)
10 20 30 40 50 60
pF1KE6 MAEVHVIGQIMGASGFSESSLFCKWGIHTGAAWKLLSGVREGQTQVDTPQIGDMAYWSHP
::::::::::.:::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MAEVHVIGQIIGASGFSESSLFCKWGIHTGAAWKLLSGVREGQTQVDTPQIGDMAYWSHP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 IDLHFATKGLQGWPRLHFQVWSQDSFGRCQLAGYGFCHVPSSPGTHQLACPTWRPLGSWR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IDLHFATKGLQGWPRLHFQVWSQDSFGRCQLAGYGFCHVPSSPGTHQLACPTWRPLGSWR
70 80 90 100 110 120
130 140 150 160 170
pF1KE6 EQLARAFVGGGPQLLHGDTIYSGADRYRLHTAAGGTVHLEIGLLLRNFDRYGVEC
:::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EQLARAFVGGGPQLLHGDTIYSGADRYRLHTAAGGTVHLEIGLLLRNFDRYGVEC
130 140 150 160 170
>>NP_085055 (OMIM: 611951,614175) B9 domain-containing p (175 aa)
initn: 1261 init1: 1261 opt: 1261 Z-score: 1524.4 bits: 288.5 E(85289): 3.6e-78
Smith-Waterman score: 1261; 99.4% identity (100.0% similar) in 175 aa overlap (1-175:1-175)
10 20 30 40 50 60
pF1KE6 MAEVHVIGQIMGASGFSESSLFCKWGIHTGAAWKLLSGVREGQTQVDTPQIGDMAYWSHP
::::::::::.:::::::::::::::::::::::::::::::::::::::::::::::::
NP_085 MAEVHVIGQIIGASGFSESSLFCKWGIHTGAAWKLLSGVREGQTQVDTPQIGDMAYWSHP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 IDLHFATKGLQGWPRLHFQVWSQDSFGRCQLAGYGFCHVPSSPGTHQLACPTWRPLGSWR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_085 IDLHFATKGLQGWPRLHFQVWSQDSFGRCQLAGYGFCHVPSSPGTHQLACPTWRPLGSWR
70 80 90 100 110 120
130 140 150 160 170
pF1KE6 EQLARAFVGGGPQLLHGDTIYSGADRYRLHTAAGGTVHLEIGLLLRNFDRYGVEC
:::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_085 EQLARAFVGGGPQLLHGDTIYSGADRYRLHTAAGGTVHLEIGLLLRNFDRYGVEC
130 140 150 160 170
>>XP_011525652 (OMIM: 611951,614175) PREDICTED: B9 domai (122 aa)
initn: 903 init1: 903 opt: 903 Z-score: 1096.5 bits: 208.9 E(85289): 2.4e-54
Smith-Waterman score: 903; 100.0% identity (100.0% similar) in 122 aa overlap (54-175:1-122)
30 40 50 60 70 80
pF1KE6 KWGIHTGAAWKLLSGVREGQTQVDTPQIGDMAYWSHPIDLHFATKGLQGWPRLHFQVWSQ
::::::::::::::::::::::::::::::
XP_011 MAYWSHPIDLHFATKGLQGWPRLHFQVWSQ
10 20 30
90 100 110 120 130 140
pF1KE6 DSFGRCQLAGYGFCHVPSSPGTHQLACPTWRPLGSWREQLARAFVGGGPQLLHGDTIYSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 DSFGRCQLAGYGFCHVPSSPGTHQLACPTWRPLGSWREQLARAFVGGGPQLLHGDTIYSG
40 50 60 70 80 90
150 160 170
pF1KE6 ADRYRLHTAAGGTVHLEIGLLLRNFDRYGVEC
::::::::::::::::::::::::::::::::
XP_011 ADRYRLHTAAGGTVHLEIGLLLRNFDRYGVEC
100 110 120
>>NP_056496 (OMIM: 614144,614209,617120) B9 domain-conta (204 aa)
initn: 220 init1: 153 opt: 281 Z-score: 346.3 bits: 70.8 E(85289): 1.5e-12
Smith-Waterman score: 281; 28.3% identity (59.0% similar) in 173 aa overlap (6-174:13-184)
10 20 30 40 50
pF1KE6 MAEVHVIGQIMGASGFSE-SSLFCKWGIHTGAAWKLLSGVREGQTQVDTPQ--
: ::. .:. : : ..:.::. . : : .:..:: .:. . .
NP_056 MATASPSVFLLMVNGQVESAQ-FPEYDDLYCKYCFVYGQDWAPTAGLEEGISQITSKSQD
10 20 30 40 50
60 70 80 90 100 110
pF1KE6 IGDMAYWSHPIDLHFATKGLQGWPRLHFQVWSQDSFGRCQLAGYGFCHVPSSPGTHQLAC
. . :. :::. : . . :::.. ..:.. : :: . ::: ::: ::: :. .
NP_056 VRQALVWNFPIDVTFKSTNPYGWPQIVLSVYGPDVFGNDVVRGYGAVHVPFSPGRHKRTI
60 70 80 90 100 110
120 130 140 150 160
pF1KE6 PTWRPLGSWREQ-LARAFVGGGPQLLHGDTIYSGADRYRLHTAAGGTVHLEIGLLLRNFD
: . : .. . : .. :.: :. .. .: : .. . : : : .... ...
NP_056 PMFVPESTSKLQKFTSWFMGRRPEYTDPKVVAQGEGREVTRVRSQGFVTLLFNVVTKDMR
120 130 140 150 160 170
170
pF1KE6 RYGVEC
. : .
NP_056 KLGYDTGPSDTQGVLGPSPPQSFPQ
180 190 200
>>NP_001317078 (OMIM: 614144,614209,617120) B9 domain-co (161 aa)
initn: 220 init1: 153 opt: 264 Z-score: 327.3 bits: 66.9 E(85289): 1.7e-11
Smith-Waterman score: 264; 31.0% identity (59.3% similar) in 145 aa overlap (6-146:13-156)
10 20 30 40 50
pF1KE6 MAEVHVIGQIMGASGFSE-SSLFCKWGIHTGAAWKLLSGVREGQTQVDTPQ--
: ::. .:. : : ..:.::. . : : .:..:: .:. . .
NP_001 MATASPSVFLLMVNGQVESAQ-FPEYDDLYCKYCFVYGQDWAPTAGLEEGISQITSKSQD
10 20 30 40 50
60 70 80 90 100 110
pF1KE6 IGDMAYWSHPIDLHFATKGLQGWPRLHFQVWSQDSFGRCQLAGYGFCHVPSSPGTHQLAC
. . :. :::. : . . :::.. ..:.. : :: . ::: ::: ::: :. .
NP_001 VRQALVWNFPIDVTFKSTNPYGWPQIVLSVYGPDVFGNDVVRGYGAVHVPFSPGRHKRTI
60 70 80 90 100 110
120 130 140 150 160
pF1KE6 PTWRPLGSWREQ-LARAFVGGGPQLLHGDTIYSGADRYRLHTAAGGTVHLEIGLLLRNFD
: . : .. . : .. :.: :. .. .: :
NP_001 PMFVPESTSKLQKFTSWFMGRRPEYTDPKVVAQGEGREAQPG
120 130 140 150 160
170
pF1KE6 RYGVEC
>>NP_001308147 (OMIM: 614144,614209,617120) B9 domain-co (166 aa)
initn: 220 init1: 153 opt: 264 Z-score: 327.1 bits: 66.9 E(85289): 1.8e-11
Smith-Waterman score: 264; 31.0% identity (59.3% similar) in 145 aa overlap (6-146:13-156)
10 20 30 40 50
pF1KE6 MAEVHVIGQIMGASGFSE-SSLFCKWGIHTGAAWKLLSGVREGQTQVDTPQ--
: ::. .:. : : ..:.::. . : : .:..:: .:. . .
NP_001 MATASPSVFLLMVNGQVESAQ-FPEYDDLYCKYCFVYGQDWAPTAGLEEGISQITSKSQD
10 20 30 40 50
60 70 80 90 100 110
pF1KE6 IGDMAYWSHPIDLHFATKGLQGWPRLHFQVWSQDSFGRCQLAGYGFCHVPSSPGTHQLAC
. . :. :::. : . . :::.. ..:.. : :: . ::: ::: ::: :. .
NP_001 VRQALVWNFPIDVTFKSTNPYGWPQIVLSVYGPDVFGNDVVRGYGAVHVPFSPGRHKRTI
60 70 80 90 100 110
120 130 140 150 160
pF1KE6 PTWRPLGSWREQ-LARAFVGGGPQLLHGDTIYSGADRYRLHTAAGGTVHLEIGLLLRNFD
: . : .. . : .. :.: :. .. .: :
NP_001 PMFVPESTSKLQKFTSWFMGRRPEYTDPKVVAQGEGREATFRAVCQR
120 130 140 150 160
170
pF1KE6 RYGVEC
>>NP_001308144 (OMIM: 614144,614209,617120) B9 domain-co (183 aa)
initn: 220 init1: 153 opt: 264 Z-score: 326.5 bits: 67.0 E(85289): 1.9e-11
Smith-Waterman score: 264; 31.0% identity (59.3% similar) in 145 aa overlap (6-146:13-156)
10 20 30 40 50
pF1KE6 MAEVHVIGQIMGASGFSE-SSLFCKWGIHTGAAWKLLSGVREGQTQVDTPQ--
: ::. .:. : : ..:.::. . : : .:..:: .:. . .
NP_001 MATASPSVFLLMVNGQVESAQ-FPEYDDLYCKYCFVYGQDWAPTAGLEEGISQITSKSQD
10 20 30 40 50
60 70 80 90 100 110
pF1KE6 IGDMAYWSHPIDLHFATKGLQGWPRLHFQVWSQDSFGRCQLAGYGFCHVPSSPGTHQLAC
. . :. :::. : . . :::.. ..:.. : :: . ::: ::: ::: :. .
NP_001 VRQALVWNFPIDVTFKSTNPYGWPQIVLSVYGPDVFGNDVVRGYGAVHVPFSPGRHKRTI
60 70 80 90 100 110
120 130 140 150 160
pF1KE6 PTWRPLGSWREQ-LARAFVGGGPQLLHGDTIYSGADRYRLHTAAGGTVHLEIGLLLRNFD
: . : .. . : .. :.: :. .. .: :
NP_001 PMFVPESTSKLQKFTSWFMGRRPEYTDPKVVAQGEGREGKAPSPLLPPSPIQVTAWEWVG
120 130 140 150 160 170
170
pF1KE6 RYGVEC
NP_001 PGLG
180
>>NP_001308146 (OMIM: 614144,614209,617120) B9 domain-co (186 aa)
initn: 249 init1: 182 opt: 264 Z-score: 326.4 bits: 67.0 E(85289): 1.9e-11
Smith-Waterman score: 264; 31.0% identity (59.3% similar) in 145 aa overlap (6-146:13-156)
10 20 30 40 50
pF1KE6 MAEVHVIGQIMGASGFSE-SSLFCKWGIHTGAAWKLLSGVREGQTQVDTPQ--
: ::. .:. : : ..:.::. . : : .:..:: .:. . .
NP_001 MATASPSVFLLMVNGQVESAQ-FPEYDDLYCKYCFVYGQDWAPTAGLEEGISQITSKSQD
10 20 30 40 50
60 70 80 90 100 110
pF1KE6 IGDMAYWSHPIDLHFATKGLQGWPRLHFQVWSQDSFGRCQLAGYGFCHVPSSPGTHQLAC
. . :. :::. : . . :::.. ..:.. : :: . ::: ::: ::: :. .
NP_001 VRQALVWNFPIDVTFKSTNPYGWPQIVLSVYGPDVFGNDVVRGYGAVHVPFSPGRHKRTI
60 70 80 90 100 110
120 130 140 150 160
pF1KE6 PTWRPLGSWREQ-LARAFVGGGPQLLHGDTIYSGADRYRLHTAAGGTVHLEIGLLLRNFD
: . : .. . : .. :.: :. .. .: :
NP_001 PMFVPESTSKLQKFTSWFMGRRPEYTDPKVVAQGEGREAITAPRKAVFSVHGLTSPRALA
120 130 140 150 160 170
170
pF1KE6 RYGVEC
NP_001 LVHIKGT
180
>>NP_001308143 (OMIM: 614144,614209,617120) B9 domain-co (187 aa)
initn: 220 init1: 153 opt: 264 Z-score: 326.4 bits: 67.0 E(85289): 1.9e-11
Smith-Waterman score: 264; 31.0% identity (59.3% similar) in 145 aa overlap (6-146:13-156)
10 20 30 40 50
pF1KE6 MAEVHVIGQIMGASGFSE-SSLFCKWGIHTGAAWKLLSGVREGQTQVDTPQ--
: ::. .:. : : ..:.::. . : : .:..:: .:. . .
NP_001 MATASPSVFLLMVNGQVESAQ-FPEYDDLYCKYCFVYGQDWAPTAGLEEGISQITSKSQD
10 20 30 40 50
60 70 80 90 100 110
pF1KE6 IGDMAYWSHPIDLHFATKGLQGWPRLHFQVWSQDSFGRCQLAGYGFCHVPSSPGTHQLAC
. . :. :::. : . . :::.. ..:.. : :: . ::: ::: ::: :. .
NP_001 VRQALVWNFPIDVTFKSTNPYGWPQIVLSVYGPDVFGNDVVRGYGAVHVPFSPGRHKRTI
60 70 80 90 100 110
120 130 140 150 160
pF1KE6 PTWRPLGSWREQ-LARAFVGGGPQLLHGDTIYSGADRYRLHTAAGGTVHLEIGLLLRNFD
: . : .. . : .. :.: :. .. .: :
NP_001 PMFVPESTSKLQKFTSWFMGRRPEYTDPKVVAQGEGREDENAEAEIPRSTWVSLCPSPAW
120 130 140 150 160 170
170
pF1KE6 RYGVEC
NP_001 LMLPFCPQ
180
>>XP_005256667 (OMIM: 614144,614209,617120) PREDICTED: B (142 aa)
initn: 220 init1: 153 opt: 247 Z-score: 307.6 bits: 63.1 E(85289): 2.1e-10
Smith-Waterman score: 247; 33.3% identity (61.7% similar) in 120 aa overlap (6-122:13-131)
10 20 30 40 50
pF1KE6 MAEVHVIGQIMGASGFSE-SSLFCKWGIHTGAAWKLLSGVREGQTQVDTPQ--
: ::. .:. : : ..:.::. . : : .:..:: .:. . .
XP_005 MATASPSVFLLMVNGQVESAQ-FPEYDDLYCKYCFVYGQDWAPTAGLEEGISQITSKSQD
10 20 30 40 50
60 70 80 90 100 110
pF1KE6 IGDMAYWSHPIDLHFATKGLQGWPRLHFQVWSQDSFGRCQLAGYGFCHVPSSPGTHQLAC
. . :. :::. : . . :::.. ..:.. : :: . ::: ::: ::: :. .
XP_005 VRQALVWNFPIDVTFKSTNPYGWPQIVLSVYGPDVFGNDVVRGYGAVHVPFSPGRHKRTI
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE6 PTWRPLGSWREQLARAFVGGGPQLLHGDTIYSGADRYRLHTAAGGTVHLEIGLLLRNFDR
: . : .. . :
XP_005 PMFVPESTSKLQKFTRSASCSTH
120 130 140
175 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Nov 8 13:58:14 2016 done: Tue Nov 8 13:58:14 2016
Total Scan time: 4.230 Total Display time: -0.010
Function used was FASTA [36.3.4 Apr, 2011]