Result of FASTA (ccds) for
pFN21AE6505
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE6505, 200 aa
1>>>pF1KE6505 200 - 200 aa - 200 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 4.8360+/-0.000617; mu= 15.7928+/- 0.037
mean_var=58.2615+/-11.532, 0's: 0 Z-trim(110.8): 11 B-trim: 0 in 0/50
Lambda= 0.168029
statistics sampled from 11901 (11908) to 11901 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.756), E-opt: 0.2 (0.366), width: 16
Scan time: 1.550
The best scores are: opt bits E(32554)
CCDS72877.1 HFE2 gene_id:148738|Hs108|chr1 ( 200) 1323 328.2 2e-90
CCDS72878.1 HFE2 gene_id:148738|Hs108|chr1 ( 313) 1323 328.4 2.9e-90
CCDS72879.1 HFE2 gene_id:148738|Hs108|chr1 ( 426) 1323 328.4 3.7e-90
CCDS53973.1 RGMA gene_id:56963|Hs108|chr15 ( 434) 366 96.5 2.6e-20
CCDS45357.1 RGMA gene_id:56963|Hs108|chr15 ( 450) 366 96.5 2.7e-20
CCDS53974.1 RGMA gene_id:56963|Hs108|chr15 ( 458) 366 96.5 2.7e-20
CCDS47251.1 RGMB gene_id:285704|Hs108|chr5 ( 478) 256 69.8 3e-12
>>CCDS72877.1 HFE2 gene_id:148738|Hs108|chr1 (200 aa)
initn: 1323 init1: 1323 opt: 1323 Z-score: 1736.9 bits: 328.2 E(32554): 2e-90
Smith-Waterman score: 1323; 100.0% identity (100.0% similar) in 200 aa overlap (1-200:1-200)
10 20 30 40 50 60
pF1KE6 MQECIDQKVYQAEVDNLPVAFEDGSINGGDRPGGSSLSIQTANPGNHVEIQAAYIGTTII
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS72 MQECIDQKVYQAEVDNLPVAFEDGSINGGDRPGGSSLSIQTANPGNHVEIQAAYIGTTII
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 IRQTAGQLSFSIKVAEDVAMAFSAEQDLQLCVGGCPPSQRLSRSERNRRGAITIDTARRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS72 IRQTAGQLSFSIKVAEDVAMAFSAEQDLQLCVGGCPPSQRLSRSERNRRGAITIDTARRL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 CKEGLPVEDAYFHSCVFDVLISGDPNFTVAAQAALEDARAFLPDLEKLHLFPSDAGVPLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS72 CKEGLPVEDAYFHSCVFDVLISGDPNFTVAAQAALEDARAFLPDLEKLHLFPSDAGVPLS
130 140 150 160 170 180
190 200
pF1KE6 SATLLAPLLSGLFVLWLCIQ
::::::::::::::::::::
CCDS72 SATLLAPLLSGLFVLWLCIQ
190 200
>>CCDS72878.1 HFE2 gene_id:148738|Hs108|chr1 (313 aa)
initn: 1323 init1: 1323 opt: 1323 Z-score: 1734.0 bits: 328.4 E(32554): 2.9e-90
Smith-Waterman score: 1323; 100.0% identity (100.0% similar) in 200 aa overlap (1-200:114-313)
10 20 30
pF1KE6 MQECIDQKVYQAEVDNLPVAFEDGSINGGD
::::::::::::::::::::::::::::::
CCDS72 DFLFVQATSSPMALGANATATRKLTIIFKNMQECIDQKVYQAEVDNLPVAFEDGSINGGD
90 100 110 120 130 140
40 50 60 70 80 90
pF1KE6 RPGGSSLSIQTANPGNHVEIQAAYIGTTIIIRQTAGQLSFSIKVAEDVAMAFSAEQDLQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS72 RPGGSSLSIQTANPGNHVEIQAAYIGTTIIIRQTAGQLSFSIKVAEDVAMAFSAEQDLQL
150 160 170 180 190 200
100 110 120 130 140 150
pF1KE6 CVGGCPPSQRLSRSERNRRGAITIDTARRLCKEGLPVEDAYFHSCVFDVLISGDPNFTVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS72 CVGGCPPSQRLSRSERNRRGAITIDTARRLCKEGLPVEDAYFHSCVFDVLISGDPNFTVA
210 220 230 240 250 260
160 170 180 190 200
pF1KE6 AQAALEDARAFLPDLEKLHLFPSDAGVPLSSATLLAPLLSGLFVLWLCIQ
::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS72 AQAALEDARAFLPDLEKLHLFPSDAGVPLSSATLLAPLLSGLFVLWLCIQ
270 280 290 300 310
>>CCDS72879.1 HFE2 gene_id:148738|Hs108|chr1 (426 aa)
initn: 1323 init1: 1323 opt: 1323 Z-score: 1732.1 bits: 328.4 E(32554): 3.7e-90
Smith-Waterman score: 1323; 100.0% identity (100.0% similar) in 200 aa overlap (1-200:227-426)
10 20 30
pF1KE6 MQECIDQKVYQAEVDNLPVAFEDGSINGGD
::::::::::::::::::::::::::::::
CCDS72 DFLFVQATSSPMALGANATATRKLTIIFKNMQECIDQKVYQAEVDNLPVAFEDGSINGGD
200 210 220 230 240 250
40 50 60 70 80 90
pF1KE6 RPGGSSLSIQTANPGNHVEIQAAYIGTTIIIRQTAGQLSFSIKVAEDVAMAFSAEQDLQL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS72 RPGGSSLSIQTANPGNHVEIQAAYIGTTIIIRQTAGQLSFSIKVAEDVAMAFSAEQDLQL
260 270 280 290 300 310
100 110 120 130 140 150
pF1KE6 CVGGCPPSQRLSRSERNRRGAITIDTARRLCKEGLPVEDAYFHSCVFDVLISGDPNFTVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS72 CVGGCPPSQRLSRSERNRRGAITIDTARRLCKEGLPVEDAYFHSCVFDVLISGDPNFTVA
320 330 340 350 360 370
160 170 180 190 200
pF1KE6 AQAALEDARAFLPDLEKLHLFPSDAGVPLSSATLLAPLLSGLFVLWLCIQ
::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS72 AQAALEDARAFLPDLEKLHLFPSDAGVPLSSATLLAPLLSGLFVLWLCIQ
380 390 400 410 420
>>CCDS53973.1 RGMA gene_id:56963|Hs108|chr15 (434 aa)
initn: 591 init1: 321 opt: 366 Z-score: 478.2 bits: 96.5 E(32554): 2.6e-20
Smith-Waterman score: 543; 44.4% identity (65.5% similar) in 223 aa overlap (2-195:208-430)
10 20 30
pF1KE6 MQECIDQKVYQAEVDNLPVAFEDGSINGGDR
:::.::::::::.:.::.:: ::: ::::.
CCDS53 YLNVQVTNTPVLPGSAATATSKLTIIFKNFQECVDQKVYQAEMDELPAAFVDGSKNGGDK
180 190 200 210 220 230
40 50 60 70 80
pF1KE6 PGGSSLSIQTANPGNHVEIQAAYIGTTIIIRQTAGQLSFSIKVAEDVAMAFSA--EQDLQ
:..::.: :.:::::: ::::::..::.. :.:.... :.:. : : :
CCDS53 HGANSLKITEKVSGQHVEIQAKYIGTTIVVRQVGRYLTFAVRMPEEVVNAVEDWDSQGLY
240 250 260 270 280 290
90 100 110 120 130
pF1KE6 LCVGGCPPSQRL--------SRSERNRRGAIT-----------IDTARRLCKEGLPVEDA
::. ::: .:.. ... :: : . .:: ::: :::::
CCDS53 LCLRGCPLNQQIDFQAFHTNAEGTGARRLAAASPAPTAPETFPYETAVAKCKEKLPVEDL
300 310 320 330 340 350
140 150 160 170 180
pF1KE6 YFHSCVFDVLISGDPNFTVAAQAALEDARAFLPDLEKLHLF------P--SDAGVPLSSA
:...::::.: .:: :::.:: ::::.. . . .::::. : . ::.::.
CCDS53 YYQACVFDLLTTGDVNFTLAAYYALEDVKMLHSNKDKLHLYERTRDLPGRAAAGLPLAPR
360 370 380 390 400 410
190 200
pF1KE6 TLLAPLLSGLFVLWLCIQ
::. :. : .:
CCDS53 PLLGALVPLLALLPVFC
420 430
>>CCDS45357.1 RGMA gene_id:56963|Hs108|chr15 (450 aa)
initn: 591 init1: 321 opt: 366 Z-score: 477.9 bits: 96.5 E(32554): 2.7e-20
Smith-Waterman score: 543; 44.4% identity (65.5% similar) in 223 aa overlap (2-195:224-446)
10 20 30
pF1KE6 MQECIDQKVYQAEVDNLPVAFEDGSINGGDR
:::.::::::::.:.::.:: ::: ::::.
CCDS45 YLNVQVTNTPVLPGSAATATSKLTIIFKNFQECVDQKVYQAEMDELPAAFVDGSKNGGDK
200 210 220 230 240 250
40 50 60 70 80
pF1KE6 PGGSSLSIQTANPGNHVEIQAAYIGTTIIIRQTAGQLSFSIKVAEDVAMAFSA--EQDLQ
:..::.: :.:::::: ::::::..::.. :.:.... :.:. : : :
CCDS45 HGANSLKITEKVSGQHVEIQAKYIGTTIVVRQVGRYLTFAVRMPEEVVNAVEDWDSQGLY
260 270 280 290 300 310
90 100 110 120 130
pF1KE6 LCVGGCPPSQRL--------SRSERNRRGAIT-----------IDTARRLCKEGLPVEDA
::. ::: .:.. ... :: : . .:: ::: :::::
CCDS45 LCLRGCPLNQQIDFQAFHTNAEGTGARRLAAASPAPTAPETFPYETAVAKCKEKLPVEDL
320 330 340 350 360 370
140 150 160 170 180
pF1KE6 YFHSCVFDVLISGDPNFTVAAQAALEDARAFLPDLEKLHLF------P--SDAGVPLSSA
:...::::.: .:: :::.:: ::::.. . . .::::. : . ::.::.
CCDS45 YYQACVFDLLTTGDVNFTLAAYYALEDVKMLHSNKDKLHLYERTRDLPGRAAAGLPLAPR
380 390 400 410 420 430
190 200
pF1KE6 TLLAPLLSGLFVLWLCIQ
::. :. : .:
CCDS45 PLLGALVPLLALLPVFC
440 450
>>CCDS53974.1 RGMA gene_id:56963|Hs108|chr15 (458 aa)
initn: 591 init1: 321 opt: 366 Z-score: 477.8 bits: 96.5 E(32554): 2.7e-20
Smith-Waterman score: 543; 44.4% identity (65.5% similar) in 223 aa overlap (2-195:232-454)
10 20 30
pF1KE6 MQECIDQKVYQAEVDNLPVAFEDGSINGGDR
:::.::::::::.:.::.:: ::: ::::.
CCDS53 YLNVQVTNTPVLPGSAATATSKLTIIFKNFQECVDQKVYQAEMDELPAAFVDGSKNGGDK
210 220 230 240 250 260
40 50 60 70 80
pF1KE6 PGGSSLSIQTANPGNHVEIQAAYIGTTIIIRQTAGQLSFSIKVAEDVAMAFSA--EQDLQ
:..::.: :.:::::: ::::::..::.. :.:.... :.:. : : :
CCDS53 HGANSLKITEKVSGQHVEIQAKYIGTTIVVRQVGRYLTFAVRMPEEVVNAVEDWDSQGLY
270 280 290 300 310 320
90 100 110 120 130
pF1KE6 LCVGGCPPSQRL--------SRSERNRRGAIT-----------IDTARRLCKEGLPVEDA
::. ::: .:.. ... :: : . .:: ::: :::::
CCDS53 LCLRGCPLNQQIDFQAFHTNAEGTGARRLAAASPAPTAPETFPYETAVAKCKEKLPVEDL
330 340 350 360 370 380
140 150 160 170 180
pF1KE6 YFHSCVFDVLISGDPNFTVAAQAALEDARAFLPDLEKLHLF------P--SDAGVPLSSA
:...::::.: .:: :::.:: ::::.. . . .::::. : . ::.::.
CCDS53 YYQACVFDLLTTGDVNFTLAAYYALEDVKMLHSNKDKLHLYERTRDLPGRAAAGLPLAPR
390 400 410 420 430 440
190 200
pF1KE6 TLLAPLLSGLFVLWLCIQ
::. :. : .:
CCDS53 PLLGALVPLLALLPVFC
450
>>CCDS47251.1 RGMB gene_id:285704|Hs108|chr5 (478 aa)
initn: 451 init1: 242 opt: 256 Z-score: 333.5 bits: 69.8 E(32554): 3e-12
Smith-Waterman score: 557; 43.7% identity (71.2% similar) in 215 aa overlap (2-199:265-476)
10 20 30
pF1KE6 MQECIDQKVYQAEVDNLPVAFEDGSINGGDR
.:: ::::::: .:.::.:: ::. .:::
CCDS47 YLSVQVTNVPVVPGSSATATNKITIIFKAHHECTDQKVYQAVTDDLPAAFVDGTTSGGDS
240 250 260 270 280 290
40 50 60 70 80 90
pF1KE6 PGGSSLSIQTANPGNHVEIQAAYIGTTIIIRQTAGQLSFSIKVAEDVAMAFSAEQDLQLC
. .:: : . :..::..: :::::...::.. :...:.. ::.::.. ::::::
CCDS47 DA-KSLRIVERESGHYVEMHARYIGTTVFVRQVGRYLTLAIRMPEDLAMSYEESQDLQLC
300 310 320 330 340 350
100 110 120 130
pF1KE6 VGGCPPSQRLSRSERN----------RRGAI------TIDTARRLCKEGLPVEDAYFHSC
:.::: :.:.. .. . : . . :..:: :.: .::.: ::.::
CCDS47 VNGCPLSERIDDGQGQVSAILGHSLPRTSLVQAWPGYTLETANTQCHEKMPVKDIYFQSC
360 370 380 390 400 410
140 150 160 170 180 190
pF1KE6 VFDVLISGDPNFTVAAQAALEDARAFLPDLEKLHLFPSDA-GVPLSSATLLAPLLSGLFV
:::.: .:: :::.::..::::..:. : :. :.:::.. :.: ... : . : ::
CCDS47 VFDLLTTGDANFTAAAHSALEDVEALHPRKERWHIFPSSGNGTPRGGSDLSVSL--GLTC
420 430 440 450 460 470
200
pF1KE6 LWLCIQ
: : .
CCDS47 LILIVFL
200 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Nov 8 13:55:30 2016 done: Tue Nov 8 13:55:30 2016
Total Scan time: 1.550 Total Display time: -0.010
Function used was FASTA [36.3.4 Apr, 2011]