Result of FASTA (omim) for
pFN21AE6472
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE6472, 462 aa
1>>>pF1KE6472 462 - 462 aa - 462 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 4.6542+/-0.000437; mu= 21.3279+/- 0.027
mean_var=70.6920+/-15.227, 0's: 0 Z-trim(110.1): 141 B-trim: 41 in 1/51
Lambda= 0.152542
statistics sampled from 18184 (18359) to 18184 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.568), E-opt: 0.2 (0.215), width: 16
Scan time: 8.070
The best scores are: opt bits E(85289)
NP_060701 (OMIM: 614236) putative sodium-coupled n ( 462) 3057 682.5 6.3e-196
XP_016878882 (OMIM: 614236) PREDICTED: putative so ( 462) 3057 682.5 6.3e-196
XP_016878884 (OMIM: 614236) PREDICTED: putative so ( 353) 2298 515.4 9.9e-146
XP_016878886 (OMIM: 614236) PREDICTED: putative so ( 344) 2288 513.2 4.5e-145
XP_016878885 (OMIM: 614236) PREDICTED: putative so ( 346) 1979 445.2 1.3e-124
XP_016878887 (OMIM: 614236) PREDICTED: putative so ( 330) 1964 441.9 1.3e-123
NP_001295313 (OMIM: 614236) putative sodium-couple ( 354) 1961 441.2 2.1e-123
XP_016878883 (OMIM: 614236) PREDICTED: putative so ( 354) 1961 441.2 2.1e-123
XP_016878888 (OMIM: 614236) PREDICTED: putative so ( 251) 1561 353.1 5.2e-97
XP_016878435 (OMIM: 609218,615585) PREDICTED: puta ( 435) 1140 260.6 6e-69
NP_001073911 (OMIM: 609218,615585) putative sodium ( 435) 1140 260.6 6e-69
XP_016876510 (OMIM: 616518) PREDICTED: probable so ( 441) 454 109.7 1.7e-23
NP_612637 (OMIM: 616525) putative sodium-coupled n ( 780) 403 98.7 6e-20
NP_001033073 (OMIM: 616525) putative sodium-couple (1119) 403 98.8 7.8e-20
XP_005257076 (OMIM: 616525) PREDICTED: putative so (1127) 403 98.8 7.8e-20
XP_011522591 (OMIM: 616525) PREDICTED: putative so (1126) 379 93.6 3.1e-18
XP_011522590 (OMIM: 616525) PREDICTED: putative so (1134) 379 93.6 3.1e-18
XP_005246407 (OMIM: 616526) PREDICTED: putative so ( 462) 369 91.0 7.5e-18
NP_722518 (OMIM: 616518) probable sodium-coupled n ( 456) 356 88.1 5.4e-17
XP_006720113 (OMIM: 616518) PREDICTED: probable so ( 255) 350 86.6 8.9e-17
XP_016876514 (OMIM: 616518) PREDICTED: probable so ( 405) 333 83.0 1.6e-15
XP_016876515 (OMIM: 616518) PREDICTED: probable so ( 405) 333 83.0 1.6e-15
XP_016876512 (OMIM: 616518) PREDICTED: probable so ( 435) 333 83.0 1.7e-15
XP_016876511 (OMIM: 616518) PREDICTED: probable so ( 436) 333 83.0 1.7e-15
XP_016876509 (OMIM: 616518) PREDICTED: probable so ( 459) 333 83.1 1.8e-15
NP_001166173 (OMIM: 616518) probable sodium-couple ( 521) 333 83.1 2e-15
XP_011522592 (OMIM: 616525) PREDICTED: putative so (1045) 336 84.1 2e-15
XP_016876516 (OMIM: 616518) PREDICTED: probable so ( 258) 327 81.5 3e-15
XP_016876517 (OMIM: 616518) PREDICTED: probable so ( 258) 327 81.5 3e-15
XP_016876513 (OMIM: 616518) PREDICTED: probable so ( 419) 324 81.0 6.7e-15
NP_001186077 (OMIM: 616526) putative sodium-couple ( 406) 321 80.4 1e-14
XP_016858951 (OMIM: 616526) PREDICTED: putative so ( 395) 311 78.2 4.6e-14
XP_016858950 (OMIM: 616526) PREDICTED: putative so ( 397) 311 78.2 4.7e-14
XP_016858949 (OMIM: 616526) PREDICTED: putative so ( 408) 311 78.2 4.7e-14
XP_016858944 (OMIM: 616526) PREDICTED: putative so ( 488) 311 78.2 5.4e-14
XP_016858952 (OMIM: 616526) PREDICTED: putative so ( 340) 280 71.3 4.7e-12
XP_016858947 (OMIM: 616526) PREDICTED: putative so ( 432) 263 67.6 7.5e-11
NP_775783 (OMIM: 616526) putative sodium-coupled n ( 384) 257 66.3 1.7e-10
XP_011509039 (OMIM: 616526) PREDICTED: putative so ( 440) 257 66.3 1.9e-10
XP_016858946 (OMIM: 616526) PREDICTED: putative so ( 463) 255 65.9 2.7e-10
NP_001265318 (OMIM: 608490) sodium-coupled neutral ( 487) 239 62.4 3.2e-09
NP_001265316 (OMIM: 608490) sodium-coupled neutral ( 487) 239 62.4 3.2e-09
NP_109599 (OMIM: 608490) sodium-coupled neutral am ( 487) 239 62.4 3.2e-09
NP_001265317 (OMIM: 608490) sodium-coupled neutral ( 487) 239 62.4 3.2e-09
NP_001070952 (OMIM: 608490) sodium-coupled neutral ( 487) 239 62.4 3.2e-09
XP_016875479 (OMIM: 608490) PREDICTED: sodium-coup ( 456) 230 60.4 1.2e-08
XP_011537089 (OMIM: 608490) PREDICTED: sodium-coup ( 456) 230 60.4 1.2e-08
XP_011537088 (OMIM: 608490) PREDICTED: sodium-coup ( 478) 229 60.2 1.4e-08
XP_011537086 (OMIM: 608490) PREDICTED: sodium-coup ( 497) 229 60.2 1.5e-08
NP_001265319 (OMIM: 608490) sodium-coupled neutral ( 503) 229 60.2 1.5e-08
>>NP_060701 (OMIM: 614236) putative sodium-coupled neutr (462 aa)
initn: 3057 init1: 3057 opt: 3057 Z-score: 3638.5 bits: 682.5 E(85289): 6.3e-196
Smith-Waterman score: 3057; 100.0% identity (100.0% similar) in 462 aa overlap (1-462:1-462)
10 20 30 40 50 60
pF1KE6 MAQVSINNDYSEWDLSTDAGERARLLQSPCVDTAPKSEWEASPGGLDRGTTSTLGAIFIV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 MAQVSINNDYSEWDLSTDAGERARLLQSPCVDTAPKSEWEASPGGLDRGTTSTLGAIFIV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 VNACLGAGLLNFPAAFSTAGGVAAGIALQMGMLVFIISGLVILAYCSQASNERTYQEVVW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 VNACLGAGLLNFPAAFSTAGGVAAGIALQMGMLVFIISGLVILAYCSQASNERTYQEVVW
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 AVCGKLTGVLCEVAIAVYTFGTCIAFLIIIGDQQDKIIAVMAKEPEGASGPWYTDRKFTI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 AVCGKLTGVLCEVAIAVYTFGTCIAFLIIIGDQQDKIIAVMAKEPEGASGPWYTDRKFTI
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE6 SLTAFLFILPLSIPREIGFQKYASFLSVVGTWYVTAIVIIKYIWPDKEMTPGNILTRPAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 SLTAFLFILPLSIPREIGFQKYASFLSVVGTWYVTAIVIIKYIWPDKEMTPGNILTRPAS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE6 WMAVFNAMPTICFGFQCHVSSVPVFNSMQQPEVKTWGGVVTAAMVIALAVYMGTGICGFL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 WMAVFNAMPTICFGFQCHVSSVPVFNSMQQPEVKTWGGVVTAAMVIALAVYMGTGICGFL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE6 TFGAAVDPDVLLSYPSEDMAVAVARAFIILSVLTSYPILHFCGRAVVEGLWLRYQGVPVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 TFGAAVDPDVLLSYPSEDMAVAVARAFIILSVLTSYPILHFCGRAVVEGLWLRYQGVPVE
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE6 EDVGRERRRRVLQTLVWFLLTLLLALFIPDIGKVISVIGGLAACFIFVFPGLCLIQAKLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_060 EDVGRERRRRVLQTLVWFLLTLLLALFIPDIGKVISVIGGLAACFIFVFPGLCLIQAKLS
370 380 390 400 410 420
430 440 450 460
pF1KE6 EMEEVKPASWWVLVSYGVLLVTLGAFIFGQTTANAIFVDLLA
::::::::::::::::::::::::::::::::::::::::::
NP_060 EMEEVKPASWWVLVSYGVLLVTLGAFIFGQTTANAIFVDLLA
430 440 450 460
>>XP_016878882 (OMIM: 614236) PREDICTED: putative sodium (462 aa)
initn: 3057 init1: 3057 opt: 3057 Z-score: 3638.5 bits: 682.5 E(85289): 6.3e-196
Smith-Waterman score: 3057; 100.0% identity (100.0% similar) in 462 aa overlap (1-462:1-462)
10 20 30 40 50 60
pF1KE6 MAQVSINNDYSEWDLSTDAGERARLLQSPCVDTAPKSEWEASPGGLDRGTTSTLGAIFIV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MAQVSINNDYSEWDLSTDAGERARLLQSPCVDTAPKSEWEASPGGLDRGTTSTLGAIFIV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 VNACLGAGLLNFPAAFSTAGGVAAGIALQMGMLVFIISGLVILAYCSQASNERTYQEVVW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VNACLGAGLLNFPAAFSTAGGVAAGIALQMGMLVFIISGLVILAYCSQASNERTYQEVVW
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 AVCGKLTGVLCEVAIAVYTFGTCIAFLIIIGDQQDKIIAVMAKEPEGASGPWYTDRKFTI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AVCGKLTGVLCEVAIAVYTFGTCIAFLIIIGDQQDKIIAVMAKEPEGASGPWYTDRKFTI
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE6 SLTAFLFILPLSIPREIGFQKYASFLSVVGTWYVTAIVIIKYIWPDKEMTPGNILTRPAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SLTAFLFILPLSIPREIGFQKYASFLSVVGTWYVTAIVIIKYIWPDKEMTPGNILTRPAS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE6 WMAVFNAMPTICFGFQCHVSSVPVFNSMQQPEVKTWGGVVTAAMVIALAVYMGTGICGFL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 WMAVFNAMPTICFGFQCHVSSVPVFNSMQQPEVKTWGGVVTAAMVIALAVYMGTGICGFL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE6 TFGAAVDPDVLLSYPSEDMAVAVARAFIILSVLTSYPILHFCGRAVVEGLWLRYQGVPVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TFGAAVDPDVLLSYPSEDMAVAVARAFIILSVLTSYPILHFCGRAVVEGLWLRYQGVPVE
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE6 EDVGRERRRRVLQTLVWFLLTLLLALFIPDIGKVISVIGGLAACFIFVFPGLCLIQAKLS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EDVGRERRRRVLQTLVWFLLTLLLALFIPDIGKVISVIGGLAACFIFVFPGLCLIQAKLS
370 380 390 400 410 420
430 440 450 460
pF1KE6 EMEEVKPASWWVLVSYGVLLVTLGAFIFGQTTANAIFVDLLA
::::::::::::::::::::::::::::::::::::::::::
XP_016 EMEEVKPASWWVLVSYGVLLVTLGAFIFGQTTANAIFVDLLA
430 440 450 460
>>XP_016878884 (OMIM: 614236) PREDICTED: putative sodium (353 aa)
initn: 2298 init1: 2298 opt: 2298 Z-score: 2737.3 bits: 515.4 E(85289): 9.9e-146
Smith-Waterman score: 2298; 100.0% identity (100.0% similar) in 346 aa overlap (1-346:1-346)
10 20 30 40 50 60
pF1KE6 MAQVSINNDYSEWDLSTDAGERARLLQSPCVDTAPKSEWEASPGGLDRGTTSTLGAIFIV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MAQVSINNDYSEWDLSTDAGERARLLQSPCVDTAPKSEWEASPGGLDRGTTSTLGAIFIV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 VNACLGAGLLNFPAAFSTAGGVAAGIALQMGMLVFIISGLVILAYCSQASNERTYQEVVW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VNACLGAGLLNFPAAFSTAGGVAAGIALQMGMLVFIISGLVILAYCSQASNERTYQEVVW
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 AVCGKLTGVLCEVAIAVYTFGTCIAFLIIIGDQQDKIIAVMAKEPEGASGPWYTDRKFTI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AVCGKLTGVLCEVAIAVYTFGTCIAFLIIIGDQQDKIIAVMAKEPEGASGPWYTDRKFTI
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE6 SLTAFLFILPLSIPREIGFQKYASFLSVVGTWYVTAIVIIKYIWPDKEMTPGNILTRPAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SLTAFLFILPLSIPREIGFQKYASFLSVVGTWYVTAIVIIKYIWPDKEMTPGNILTRPAS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE6 WMAVFNAMPTICFGFQCHVSSVPVFNSMQQPEVKTWGGVVTAAMVIALAVYMGTGICGFL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 WMAVFNAMPTICFGFQCHVSSVPVFNSMQQPEVKTWGGVVTAAMVIALAVYMGTGICGFL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE6 TFGAAVDPDVLLSYPSEDMAVAVARAFIILSVLTSYPILHFCGRAVVEGLWLRYQGVPVE
::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TFGAAVDPDVLLSYPSEDMAVAVARAFIILSVLTSYPILHFCGRAVPHSSQTL
310 320 330 340 350
370 380 390 400 410 420
pF1KE6 EDVGRERRRRVLQTLVWFLLTLLLALFIPDIGKVISVIGGLAACFIFVFPGLCLIQAKLS
>>XP_016878886 (OMIM: 614236) PREDICTED: putative sodium (344 aa)
initn: 2288 init1: 2288 opt: 2288 Z-score: 2725.5 bits: 513.2 E(85289): 4.5e-145
Smith-Waterman score: 2288; 100.0% identity (100.0% similar) in 344 aa overlap (1-344:1-344)
10 20 30 40 50 60
pF1KE6 MAQVSINNDYSEWDLSTDAGERARLLQSPCVDTAPKSEWEASPGGLDRGTTSTLGAIFIV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MAQVSINNDYSEWDLSTDAGERARLLQSPCVDTAPKSEWEASPGGLDRGTTSTLGAIFIV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 VNACLGAGLLNFPAAFSTAGGVAAGIALQMGMLVFIISGLVILAYCSQASNERTYQEVVW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VNACLGAGLLNFPAAFSTAGGVAAGIALQMGMLVFIISGLVILAYCSQASNERTYQEVVW
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 AVCGKLTGVLCEVAIAVYTFGTCIAFLIIIGDQQDKIIAVMAKEPEGASGPWYTDRKFTI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AVCGKLTGVLCEVAIAVYTFGTCIAFLIIIGDQQDKIIAVMAKEPEGASGPWYTDRKFTI
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE6 SLTAFLFILPLSIPREIGFQKYASFLSVVGTWYVTAIVIIKYIWPDKEMTPGNILTRPAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SLTAFLFILPLSIPREIGFQKYASFLSVVGTWYVTAIVIIKYIWPDKEMTPGNILTRPAS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE6 WMAVFNAMPTICFGFQCHVSSVPVFNSMQQPEVKTWGGVVTAAMVIALAVYMGTGICGFL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 WMAVFNAMPTICFGFQCHVSSVPVFNSMQQPEVKTWGGVVTAAMVIALAVYMGTGICGFL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE6 TFGAAVDPDVLLSYPSEDMAVAVARAFIILSVLTSYPILHFCGRAVVEGLWLRYQGVPVE
::::::::::::::::::::::::::::::::::::::::::::
XP_016 TFGAAVDPDVLLSYPSEDMAVAVARAFIILSVLTSYPILHFCGR
310 320 330 340
370 380 390 400 410 420
pF1KE6 EDVGRERRRRVLQTLVWFLLTLLLALFIPDIGKVISVIGGLAACFIFVFPGLCLIQAKLS
>>XP_016878885 (OMIM: 614236) PREDICTED: putative sodium (346 aa)
initn: 1979 init1: 1979 opt: 1979 Z-score: 2358.0 bits: 445.2 E(85289): 1.3e-124
Smith-Waterman score: 2047; 74.9% identity (74.9% similar) in 462 aa overlap (1-462:1-346)
10 20 30 40 50 60
pF1KE6 MAQVSINNDYSEWDLSTDAGERARLLQSPCVDTAPKSEWEASPGGLDRGTTSTLGAIFIV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MAQVSINNDYSEWDLSTDAGERARLLQSPCVDTAPKSEWEASPGGLDRGTTSTLGAIFIV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 VNACLGAGLLNFPAAFSTAGGVAAGIALQMGMLVFIISGLVILAYCSQASNERTYQEVVW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VNACLGAGLLNFPAAFSTAGGVAAGIALQMGMLVFIISGLVILAYCSQASNERTYQEVVW
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 AVCGKLTGVLCEVAIAVYTFGTCIAFLIIIGDQQDKIIAVMAKEPEGASGPWYTDRKFTI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AVCGKLTGVLCEVAIAVYTFGTCIAFLIIIGDQQDKIIAVMAKEPEGASGPWYTDRKFTI
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE6 SLTAFLFILPLSIPREIGFQKYASFLSVVGTWYVTAIVIIKYIWPDKEMTPGNILTRPAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SLTAFLFILPLSIPREIGFQKYASFLSVVGTWYVTAIVIIKYIWPDKEMTPGNILTRPAS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE6 WMAVFNAMPTICFGFQCHVSSVPVFNSMQQPEVKTWGGVVTAAMVIALAVYMGTGICGFL
:::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 WMAVFNAMPTICFGFQCHVSSVPVFNSMQQPEVKTWGGVVTAAMVIALAVYMGTG-----
250 260 270 280 290
310 320 330 340 350 360
pF1KE6 TFGAAVDPDVLLSYPSEDMAVAVARAFIILSVLTSYPILHFCGRAVVEGLWLRYQGVPVE
XP_016 ------------------------------------------------------------
370 380 390 400 410 420
pF1KE6 EDVGRERRRRVLQTLVWFLLTLLLALFIPDIGKVISVIGGLAACFIFVFPGLCLIQAKLS
:::::::::
XP_016 ---------------------------------------------------LCLIQAKLS
300
430 440 450 460
pF1KE6 EMEEVKPASWWVLVSYGVLLVTLGAFIFGQTTANAIFVDLLA
::::::::::::::::::::::::::::::::::::::::::
XP_016 EMEEVKPASWWVLVSYGVLLVTLGAFIFGQTTANAIFVDLLA
310 320 330 340
>>XP_016878887 (OMIM: 614236) PREDICTED: putative sodium (330 aa)
initn: 1964 init1: 1964 opt: 1964 Z-score: 2340.4 bits: 441.9 E(85289): 1.3e-123
Smith-Waterman score: 1964; 100.0% identity (100.0% similar) in 295 aa overlap (1-295:1-295)
10 20 30 40 50 60
pF1KE6 MAQVSINNDYSEWDLSTDAGERARLLQSPCVDTAPKSEWEASPGGLDRGTTSTLGAIFIV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MAQVSINNDYSEWDLSTDAGERARLLQSPCVDTAPKSEWEASPGGLDRGTTSTLGAIFIV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 VNACLGAGLLNFPAAFSTAGGVAAGIALQMGMLVFIISGLVILAYCSQASNERTYQEVVW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VNACLGAGLLNFPAAFSTAGGVAAGIALQMGMLVFIISGLVILAYCSQASNERTYQEVVW
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 AVCGKLTGVLCEVAIAVYTFGTCIAFLIIIGDQQDKIIAVMAKEPEGASGPWYTDRKFTI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AVCGKLTGVLCEVAIAVYTFGTCIAFLIIIGDQQDKIIAVMAKEPEGASGPWYTDRKFTI
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE6 SLTAFLFILPLSIPREIGFQKYASFLSVVGTWYVTAIVIIKYIWPDKEMTPGNILTRPAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SLTAFLFILPLSIPREIGFQKYASFLSVVGTWYVTAIVIIKYIWPDKEMTPGNILTRPAS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE6 WMAVFNAMPTICFGFQCHVSSVPVFNSMQQPEVKTWGGVVTAAMVIALAVYMGTGICGFL
:::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 WMAVFNAMPTICFGFQCHVSSVPVFNSMQQPEVKTWGGVVTAAMVIALAVYMGTGSARNG
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE6 TFGAAVDPDVLLSYPSEDMAVAVARAFIILSVLTSYPILHFCGRAVVEGLWLRYQGVPVE
XP_016 SQHGGCHGERQNWSCPHGVDILVGETVMQE
310 320 330
>>NP_001295313 (OMIM: 614236) putative sodium-coupled ne (354 aa)
initn: 1956 init1: 1956 opt: 1961 Z-score: 2336.5 bits: 441.2 E(85289): 2.1e-123
Smith-Waterman score: 1961; 99.3% identity (99.3% similar) in 298 aa overlap (1-297:1-298)
10 20 30 40 50 60
pF1KE6 MAQVSINNDYSEWDLSTDAGERARLLQSPCVDTAPKSEWEASPGGLDRGTTSTLGAIFIV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MAQVSINNDYSEWDLSTDAGERARLLQSPCVDTAPKSEWEASPGGLDRGTTSTLGAIFIV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 VNACLGAGLLNFPAAFSTAGGVAAGIALQMGMLVFIISGLVILAYCSQASNERTYQEVVW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VNACLGAGLLNFPAAFSTAGGVAAGIALQMGMLVFIISGLVILAYCSQASNERTYQEVVW
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 AVCGKLTGVLCEVAIAVYTFGTCIAFLIIIGDQQDKIIAVMAKEPEGASGPWYTDRKFTI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AVCGKLTGVLCEVAIAVYTFGTCIAFLIIIGDQQDKIIAVMAKEPEGASGPWYTDRKFTI
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE6 SLTAFLFILPLSIPREIGFQKYASFLSVVGTWYVTAIVIIKYIWPDKEMTPGNILTRPAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SLTAFLFILPLSIPREIGFQKYASFLSVVGTWYVTAIVIIKYIWPDKEMTPGNILTRPAS
190 200 210 220 230 240
250 260 270 280 290
pF1KE6 WMAVFNAMPTICFGFQCHVSSVPVFNSMQQPEVKTWGGVVTAAMVIALAVYMGT-GICGF
:::::::::::::::::::::::::::::::::::::::::::::::::::::: : :
NP_001 WMAVFNAMPTICFGFQCHVSSVPVFNSMQQPEVKTWGGVVTAAMVIALAVYMGTAGGCWS
250 260 270 280 290 300
300 310 320 330 340 350
pF1KE6 LTFGAAVDPDVLLSYPSEDMAVAVARAFIILSVLTSYPILHFCGRAVVEGLWLRYQGVPV
NP_001 ATESSWSPWEPSSSARPQPTPSLWISWHNHCLPGNTRPLPLVAGTHLLELWGHS
310 320 330 340 350
>>XP_016878883 (OMIM: 614236) PREDICTED: putative sodium (354 aa)
initn: 1956 init1: 1956 opt: 1961 Z-score: 2336.5 bits: 441.2 E(85289): 2.1e-123
Smith-Waterman score: 1961; 99.3% identity (99.3% similar) in 298 aa overlap (1-297:1-298)
10 20 30 40 50 60
pF1KE6 MAQVSINNDYSEWDLSTDAGERARLLQSPCVDTAPKSEWEASPGGLDRGTTSTLGAIFIV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MAQVSINNDYSEWDLSTDAGERARLLQSPCVDTAPKSEWEASPGGLDRGTTSTLGAIFIV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 VNACLGAGLLNFPAAFSTAGGVAAGIALQMGMLVFIISGLVILAYCSQASNERTYQEVVW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VNACLGAGLLNFPAAFSTAGGVAAGIALQMGMLVFIISGLVILAYCSQASNERTYQEVVW
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 AVCGKLTGVLCEVAIAVYTFGTCIAFLIIIGDQQDKIIAVMAKEPEGASGPWYTDRKFTI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AVCGKLTGVLCEVAIAVYTFGTCIAFLIIIGDQQDKIIAVMAKEPEGASGPWYTDRKFTI
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE6 SLTAFLFILPLSIPREIGFQKYASFLSVVGTWYVTAIVIIKYIWPDKEMTPGNILTRPAS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SLTAFLFILPLSIPREIGFQKYASFLSVVGTWYVTAIVIIKYIWPDKEMTPGNILTRPAS
190 200 210 220 230 240
250 260 270 280 290
pF1KE6 WMAVFNAMPTICFGFQCHVSSVPVFNSMQQPEVKTWGGVVTAAMVIALAVYMGT-GICGF
:::::::::::::::::::::::::::::::::::::::::::::::::::::: : :
XP_016 WMAVFNAMPTICFGFQCHVSSVPVFNSMQQPEVKTWGGVVTAAMVIALAVYMGTAGGCWS
250 260 270 280 290 300
300 310 320 330 340 350
pF1KE6 LTFGAAVDPDVLLSYPSEDMAVAVARAFIILSVLTSYPILHFCGRAVVEGLWLRYQGVPV
XP_016 ATESSWSPWEPSSSARPQPTPSLWISWHNHCLPGNTRPLPLVAGTHLLELWGHS
310 320 330 340 350
>>XP_016878888 (OMIM: 614236) PREDICTED: putative sodium (251 aa)
initn: 1561 init1: 1561 opt: 1561 Z-score: 1862.6 bits: 353.1 E(85289): 5.2e-97
Smith-Waterman score: 1561; 100.0% identity (100.0% similar) in 237 aa overlap (1-237:1-237)
10 20 30 40 50 60
pF1KE6 MAQVSINNDYSEWDLSTDAGERARLLQSPCVDTAPKSEWEASPGGLDRGTTSTLGAIFIV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MAQVSINNDYSEWDLSTDAGERARLLQSPCVDTAPKSEWEASPGGLDRGTTSTLGAIFIV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 VNACLGAGLLNFPAAFSTAGGVAAGIALQMGMLVFIISGLVILAYCSQASNERTYQEVVW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VNACLGAGLLNFPAAFSTAGGVAAGIALQMGMLVFIISGLVILAYCSQASNERTYQEVVW
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 AVCGKLTGVLCEVAIAVYTFGTCIAFLIIIGDQQDKIIAVMAKEPEGASGPWYTDRKFTI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AVCGKLTGVLCEVAIAVYTFGTCIAFLIIIGDQQDKIIAVMAKEPEGASGPWYTDRKFTI
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE6 SLTAFLFILPLSIPREIGFQKYASFLSVVGTWYVTAIVIIKYIWPDKEMTPGNILTRPAS
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SLTAFLFILPLSIPREIGFQKYASFLSVVGTWYVTAIVIIKYIWPDKEMTPGNILTRYLP
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE6 WMAVFNAMPTICFGFQCHVSSVPVFNSMQQPEVKTWGGVVTAAMVIALAVYMGTGICGFL
XP_016 LETGVEVISPP
250
>>XP_016878435 (OMIM: 609218,615585) PREDICTED: putative (435 aa)
initn: 1136 init1: 474 opt: 1140 Z-score: 1358.9 bits: 260.6 E(85289): 6e-69
Smith-Waterman score: 1140; 41.5% identity (70.0% similar) in 436 aa overlap (27-457:4-432)
10 20 30 40 50 60
pF1KE6 MAQVSINNDYSEWDLSTDAGERARLLQSPCVDTAPKSEWEASPGGLDRGTTSTLGAIFIV
:.: :.. :. .. : :..::.::.
XP_016 MEGQTPGSRGLPEKPHPATAAA----TLSSMGAVFIL
10 20 30
70 80 90 100 110 120
pF1KE6 VNACLGAGLLNFPAAFSTAGGVAAGIALQMGMLVFIISGLVILAYCSQASNERTYQEVVW
... ::::::::: ::: ::::. .. ... :::.:::::::.: . .:.. ::: ::
XP_016 MKSALGAGLLNFPWAFSKAGGVVPAFLVELVSLVFLISGLVILGYAAAVSGQATYQGVVR
40 50 60 70 80 90
130 140 150 160 170 180
pF1KE6 AVCGKLTGVLCEVAIAVYTFGTCIAFLIIIGDQQDKIIAVMAKEPEGASGPWYTDRKFTI
..:: : :::. . . . .::: .:::: .:. . . : :::.:..::.
XP_016 GLCGPAIGKLCEACFLLNLLMISVAFLRVIGDQLEKLCDSLLSGTPPAPQPWYADQRFTL
100 110 120 130 140 150
190 200 210 220 230
pF1KE6 SLTAFLFILPLSIPREIGFQKYASFLSVVGTWYVTAIVIIKY-IWPDKEMTPGNILTRPA
: . : ::::: ::::.::::.:.:..... :.. .. ..: .::. . .. ::
XP_016 PLLSVLVILPLSAPREIAFQKYTSILGTLAACYLALVITVQYYLWPQGLVRESHPSLSPA
160 170 180 190 200 210
240 250 260 270 280 290
pF1KE6 SWMAVFNAMPTICFGFQCHVSSVPVFNSMQQPEVKTWGGVVTAAMVIALAVYMGTGICGF
:: .::...:::::::::: ..: .. ::.. .. :. : . ... .: ::. ::
XP_016 SWTSVFSVFPTICFGFQCHEAAVSIYCSMRKRSLSHWALVSVLSLLACCLIYSLTGVYGF
220 230 240 250 260 270
300 310 320 330 340 350
pF1KE6 LTFGAAVDPDVLLSYPSEDMAVAVARAFIILSVLTSYPILHFCGRAVVEGLWLRY----Q
::::. :. :::.:::..::.. :::... .:..: :::. : ::.:.. .: :
XP_016 LTFGTEVSADVLMSYPGNDMVIIVARVLFAVSIVTVYPIVLFLGRSVMQDFWRRSCLGGW
280 290 300 310 320 330
360 370 380 390 400 410
pF1KE6 GVPVEEDVGRERRRRVLQTLVWFLLTLLLALFIPDIGKVISVIGGLAACFIFVFPGLCLI
: . : . : : :..: .:: .:::.::.....:.:::... :::.:::::::
XP_016 GPSALADPSGLWVRMPL-TILWVTVTLAMALFMPDLSEIVSIIGGISSFFIFIFPGLCLI
340 350 360 370 380 390
420 430 440 450 460
pF1KE6 QAKLSEMEEVKPASWWVLVSYGVLLVTLGAFIFGQTTANAIFVDLLA
: .: . : : .::. : .:.:::::.:: :..
XP_016 CA--MGVEPIGPRVKCCLEVWGVVSVLVGTFIFGQSTAAAVWEMF
400 410 420 430
462 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Nov 8 13:37:55 2016 done: Tue Nov 8 13:37:56 2016
Total Scan time: 8.070 Total Display time: 0.040
Function used was FASTA [36.3.4 Apr, 2011]