Result of FASTA (omim) for
pFN21AE6470
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE6470, 504 aa
1>>>pF1KE6470 504 - 504 aa - 504 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.0302+/-0.000496; mu= 19.4860+/- 0.031
mean_var=69.3163+/-14.542, 0's: 0 Z-trim(108.2): 113 B-trim: 18 in 1/49
Lambda= 0.154048
statistics sampled from 16136 (16250) to 16136 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.54), E-opt: 0.2 (0.191), width: 16
Scan time: 5.340
The best scores are: opt bits E(85289)
NP_689526 (OMIM: 613760) proton-coupled amino acid ( 504) 3285 740.0 3.8e-213
XP_016872663 (OMIM: 613760) PREDICTED: proton-coup ( 407) 2627 593.7 3.4e-169
XP_016872664 (OMIM: 613760) PREDICTED: proton-coup ( 398) 2596 586.8 4e-167
NP_001273068 (OMIM: 613760) proton-coupled amino a ( 369) 2399 543.0 5.7e-154
XP_016872665 (OMIM: 613760) PREDICTED: proton-coup ( 369) 2399 543.0 5.7e-154
XP_016872666 (OMIM: 613760) PREDICTED: proton-coup ( 272) 1741 396.6 4.7e-110
XP_011535887 (OMIM: 606561) PREDICTED: proton-coup ( 476) 1593 363.9 5.8e-100
XP_011535889 (OMIM: 606561) PREDICTED: proton-coup ( 476) 1593 363.9 5.8e-100
XP_011535891 (OMIM: 606561) PREDICTED: proton-coup ( 476) 1593 363.9 5.8e-100
XP_011535888 (OMIM: 606561) PREDICTED: proton-coup ( 476) 1593 363.9 5.8e-100
XP_016864705 (OMIM: 606561) PREDICTED: proton-coup ( 476) 1593 363.9 5.8e-100
XP_011535890 (OMIM: 606561) PREDICTED: proton-coup ( 476) 1593 363.9 5.8e-100
XP_011535885 (OMIM: 606561) PREDICTED: proton-coup ( 476) 1593 363.9 5.8e-100
XP_011535886 (OMIM: 606561) PREDICTED: proton-coup ( 476) 1593 363.9 5.8e-100
XP_011535883 (OMIM: 606561) PREDICTED: proton-coup ( 476) 1593 363.9 5.8e-100
XP_005268443 (OMIM: 606561) PREDICTED: proton-coup ( 476) 1593 363.9 5.8e-100
NP_510968 (OMIM: 606561) proton-coupled amino acid ( 476) 1593 363.9 5.8e-100
XP_011535894 (OMIM: 606561) PREDICTED: proton-coup ( 476) 1593 363.9 5.8e-100
XP_011535892 (OMIM: 606561) PREDICTED: proton-coup ( 476) 1593 363.9 5.8e-100
XP_011535893 (OMIM: 606561) PREDICTED: proton-coup ( 476) 1593 363.9 5.8e-100
XP_011535882 (OMIM: 606561) PREDICTED: proton-coup ( 482) 1593 363.9 5.9e-100
NP_861441 (OMIM: 138500,242600,608331) proton-coup ( 483) 1542 352.6 1.5e-96
XP_006714822 (OMIM: 606561) PREDICTED: proton-coup ( 398) 1420 325.4 1.9e-88
XP_011535896 (OMIM: 606561) PREDICTED: proton-coup ( 448) 1420 325.4 2.1e-88
XP_011535895 (OMIM: 606561) PREDICTED: proton-coup ( 448) 1420 325.4 2.1e-88
NP_861439 (OMIM: 608332) proton-coupled amino acid ( 470) 1405 322.1 2.2e-87
NP_001295079 (OMIM: 606561) proton-coupled amino a ( 386) 1335 306.5 9e-83
XP_016864706 (OMIM: 606561) PREDICTED: proton-coup ( 418) 1335 306.5 9.6e-83
XP_011535897 (OMIM: 606561) PREDICTED: proton-coup ( 422) 1335 306.5 9.6e-83
XP_005268434 (OMIM: 138500,242600,608331) PREDICTE ( 393) 1302 299.2 1.5e-80
XP_016864708 (OMIM: 606561) PREDICTED: proton-coup ( 323) 1162 268.0 2.9e-71
XP_016864707 (OMIM: 606561) PREDICTED: proton-coup ( 362) 1158 267.1 5.9e-71
XP_011535933 (OMIM: 608332) PREDICTED: proton-coup ( 355) 1102 254.7 3.3e-67
XP_011535932 (OMIM: 608332) PREDICTED: proton-coup ( 355) 1102 254.7 3.3e-67
NP_001138489 (OMIM: 608332) proton-coupled amino a ( 511) 1053 243.9 8.2e-64
XP_016864573 (OMIM: 138500,242600,608331) PREDICTE ( 285) 1016 235.5 1.6e-61
XP_011535931 (OMIM: 608332) PREDICTED: proton-coup ( 364) 979 227.4 5.6e-59
XP_011535935 (OMIM: 608332) PREDICTED: proton-coup ( 307) 947 220.2 6.8e-57
XP_016864572 (OMIM: 138500,242600,608331) PREDICTE ( 310) 904 210.6 5.2e-54
NP_001295080 (OMIM: 606561) proton-coupled amino a ( 243) 765 179.7 8.6e-45
XP_016864709 (OMIM: 606561) PREDICTED: proton-coup ( 243) 765 179.7 8.6e-45
XP_011535898 (OMIM: 606561) PREDICTED: proton-coup ( 298) 766 180.0 8.6e-45
XP_006714819 (OMIM: 138500,242600,608331) PREDICTE ( 450) 738 173.9 8.8e-43
XP_011535929 (OMIM: 608332) PREDICTED: proton-coup ( 444) 580 138.8 3.3e-32
XP_011535936 (OMIM: 608332) PREDICTED: proton-coup ( 249) 487 117.9 3.5e-26
NP_542119 (OMIM: 616440) vesicular inhibitory amin ( 525) 223 59.5 2.8e-08
NP_060488 (OMIM: 608065) sodium-coupled neutral am ( 547) 197 53.7 1.6e-06
NP_001137296 (OMIM: 608065) sodium-coupled neutral ( 547) 197 53.7 1.6e-06
XP_005269054 (OMIM: 608065) PREDICTED: sodium-coup ( 547) 197 53.7 1.6e-06
NP_001245216 (OMIM: 616203) sodium-coupled neutral ( 498) 188 51.7 6e-06
>>NP_689526 (OMIM: 613760) proton-coupled amino acid tra (504 aa)
initn: 3285 init1: 3285 opt: 3285 Z-score: 3947.6 bits: 740.0 E(85289): 3.8e-213
Smith-Waterman score: 3285; 99.4% identity (99.8% similar) in 504 aa overlap (1-504:1-504)
10 20 30 40 50 60
pF1KE6 MEAAATPAAAGAARREELDMDVMRPLINEQNFDGTSDEEHEQELLPVQKHYQLDDQEGIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_689 MEAAATPAAAGAARREELDMDVMRPLINEQNFDGTSDEEHEQELLPVQKHYQLDDQEGIS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 FVQTLMHLLKGNIGTGLLGLPLAIKNAGIVLGPISLVFIGIISVHCMHILVRCSHFLCLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_689 FVQTLMHLLKGNIGTGLLGLPLAIKNAGIVLGPISLVFIGIISVHCMHILVRCSHFLCLR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 FKKSTLGYSDTVSFAMEVSPWSCLQKQAAWGRSVVDFFLVITQLGFCSVYIVFLAENVKQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_689 FKKSTLGYSDTVSFAMEVSPWSCLQKQAAWGRSVVDFFLVITQLGFCSVYIVFLAENVKQ
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE6 VHEGFLESKVFISNSTNSSNPCERRSVDIRIYMLCFLPFIILLVFIRELKNLFVLSFLAN
::::::::::::::::::::::::::::.:::::::::::::::::::::::::::::::
NP_689 VHEGFLESKVFISNSTNSSNPCERRSVDLRIYMLCFLPFIILLVFIRELKNLFVLSFLAN
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE6 VSMAVSLVIIYQYVVRNMPDPHNLPIVAGWKKYPLFFGTAVFAFEGIGVVLPLENQMKES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_689 VSMAVSLVIIYQYVVRNMPDPHNLPIVAGWKKYPLFFGTAVFAFEGIGVVLPLENQMKES
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE6 KRFPQALNIGMGIVTTLYVTLATLGYMCFHDEIKGSITLNLPQDVWLYQSVKILYSFGIF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_689 KRFPQALNIGMGIVTTLYVTLATLGYMCFHDEIKGSITLNLPQDVWLYQSVKILYSFGIF
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE6 VTYSIQFYVPAEIIIHGITSKFHTKWKQICEFGIRSFLVSITCAGAILIPRLDIVISFVG
::::::::::::::: ::::::::::::::::::::::::::::::::::::::::::::
NP_689 VTYSIQFYVPAEIIIPGITSKFHTKWKQICEFGIRSFLVSITCAGAILIPRLDIVISFVG
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE6 AVSSSTLAIILPPLVEILTFSKEHYNIWMVLKNISIAFTGVVGFLLGTYITVEEIIYPTP
::::::::.:::::::::::::::::::::::::::::::::::::::::::::::::::
NP_689 AVSSSTLALILPPLVEILTFSKEHYNIWMVLKNISIAFTGVVGFLLGTYITVEEIIYPTP
430 440 450 460 470 480
490 500
pF1KE6 KVVAGTPQSPFLNLNSTCLTSGLK
::::::::::::::::::::::::
NP_689 KVVAGTPQSPFLNLNSTCLTSGLK
490 500
>>XP_016872663 (OMIM: 613760) PREDICTED: proton-coupled (407 aa)
initn: 2627 init1: 2627 opt: 2627 Z-score: 3158.5 bits: 593.7 E(85289): 3.4e-169
Smith-Waterman score: 2627; 99.5% identity (99.7% similar) in 399 aa overlap (1-399:1-399)
10 20 30 40 50 60
pF1KE6 MEAAATPAAAGAARREELDMDVMRPLINEQNFDGTSDEEHEQELLPVQKHYQLDDQEGIS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MEAAATPAAAGAARREELDMDVMRPLINEQNFDGTSDEEHEQELLPVQKHYQLDDQEGIS
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 FVQTLMHLLKGNIGTGLLGLPLAIKNAGIVLGPISLVFIGIISVHCMHILVRCSHFLCLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FVQTLMHLLKGNIGTGLLGLPLAIKNAGIVLGPISLVFIGIISVHCMHILVRCSHFLCLR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 FKKSTLGYSDTVSFAMEVSPWSCLQKQAAWGRSVVDFFLVITQLGFCSVYIVFLAENVKQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FKKSTLGYSDTVSFAMEVSPWSCLQKQAAWGRSVVDFFLVITQLGFCSVYIVFLAENVKQ
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE6 VHEGFLESKVFISNSTNSSNPCERRSVDIRIYMLCFLPFIILLVFIRELKNLFVLSFLAN
::::::::::::::::::::::::::::.:::::::::::::::::::::::::::::::
XP_016 VHEGFLESKVFISNSTNSSNPCERRSVDLRIYMLCFLPFIILLVFIRELKNLFVLSFLAN
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE6 VSMAVSLVIIYQYVVRNMPDPHNLPIVAGWKKYPLFFGTAVFAFEGIGVVLPLENQMKES
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VSMAVSLVIIYQYVVRNMPDPHNLPIVAGWKKYPLFFGTAVFAFEGIGVVLPLENQMKES
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE6 KRFPQALNIGMGIVTTLYVTLATLGYMCFHDEIKGSITLNLPQDVWLYQSVKILYSFGIF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KRFPQALNIGMGIVTTLYVTLATLGYMCFHDEIKGSITLNLPQDVWLYQSVKILYSFGIF
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE6 VTYSIQFYVPAEIIIHGITSKFHTKWKQICEFGIRSFLVSITCAGAILIPRLDIVISFVG
::::::::::::::: :::::::::::::::::::::::
XP_016 VTYSIQFYVPAEIIIPGITSKFHTKWKQICEFGIRSFLVPEQFLFLV
370 380 390 400
430 440 450 460 470 480
pF1KE6 AVSSSTLAIILPPLVEILTFSKEHYNIWMVLKNISIAFTGVVGFLLGTYITVEEIIYPTP
>>XP_016872664 (OMIM: 613760) PREDICTED: proton-coupled (398 aa)
initn: 2596 init1: 2596 opt: 2596 Z-score: 3121.4 bits: 586.8 E(85289): 4e-167
Smith-Waterman score: 2596; 99.2% identity (99.7% similar) in 398 aa overlap (107-504:1-398)
80 90 100 110 120 130
pF1KE6 LLGLPLAIKNAGIVLGPISLVFIGIISVHCMHILVRCSHFLCLRFKKSTLGYSDTVSFAM
::::::::::::::::::::::::::::::
XP_016 MHILVRCSHFLCLRFKKSTLGYSDTVSFAM
10 20 30
140 150 160 170 180 190
pF1KE6 EVSPWSCLQKQAAWGRSVVDFFLVITQLGFCSVYIVFLAENVKQVHEGFLESKVFISNST
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EVSPWSCLQKQAAWGRSVVDFFLVITQLGFCSVYIVFLAENVKQVHEGFLESKVFISNST
40 50 60 70 80 90
200 210 220 230 240 250
pF1KE6 NSSNPCERRSVDIRIYMLCFLPFIILLVFIRELKNLFVLSFLANVSMAVSLVIIYQYVVR
::::::::::::.:::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NSSNPCERRSVDLRIYMLCFLPFIILLVFIRELKNLFVLSFLANVSMAVSLVIIYQYVVR
100 110 120 130 140 150
260 270 280 290 300 310
pF1KE6 NMPDPHNLPIVAGWKKYPLFFGTAVFAFEGIGVVLPLENQMKESKRFPQALNIGMGIVTT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NMPDPHNLPIVAGWKKYPLFFGTAVFAFEGIGVVLPLENQMKESKRFPQALNIGMGIVTT
160 170 180 190 200 210
320 330 340 350 360 370
pF1KE6 LYVTLATLGYMCFHDEIKGSITLNLPQDVWLYQSVKILYSFGIFVTYSIQFYVPAEIIIH
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LYVTLATLGYMCFHDEIKGSITLNLPQDVWLYQSVKILYSFGIFVTYSIQFYVPAEIIIP
220 230 240 250 260 270
380 390 400 410 420 430
pF1KE6 GITSKFHTKWKQICEFGIRSFLVSITCAGAILIPRLDIVISFVGAVSSSTLAIILPPLVE
::::::::::::::::::::::::::::::::::::::::::::::::::::.:::::::
XP_016 GITSKFHTKWKQICEFGIRSFLVSITCAGAILIPRLDIVISFVGAVSSSTLALILPPLVE
280 290 300 310 320 330
440 450 460 470 480 490
pF1KE6 ILTFSKEHYNIWMVLKNISIAFTGVVGFLLGTYITVEEIIYPTPKVVAGTPQSPFLNLNS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ILTFSKEHYNIWMVLKNISIAFTGVVGFLLGTYITVEEIIYPTPKVVAGTPQSPFLNLNS
340 350 360 370 380 390
500
pF1KE6 TCLTSGLK
::::::::
XP_016 TCLTSGLK
>>NP_001273068 (OMIM: 613760) proton-coupled amino acid (369 aa)
initn: 2399 init1: 2399 opt: 2399 Z-score: 2885.3 bits: 543.0 E(85289): 5.7e-154
Smith-Waterman score: 2399; 99.2% identity (99.7% similar) in 369 aa overlap (136-504:1-369)
110 120 130 140 150 160
pF1KE6 CMHILVRCSHFLCLRFKKSTLGYSDTVSFAMEVSPWSCLQKQAAWGRSVVDFFLVITQLG
::::::::::::::::::::::::::::::
NP_001 MEVSPWSCLQKQAAWGRSVVDFFLVITQLG
10 20 30
170 180 190 200 210 220
pF1KE6 FCSVYIVFLAENVKQVHEGFLESKVFISNSTNSSNPCERRSVDIRIYMLCFLPFIILLVF
:::::::::::::::::::::::::::::::::::::::::::.::::::::::::::::
NP_001 FCSVYIVFLAENVKQVHEGFLESKVFISNSTNSSNPCERRSVDLRIYMLCFLPFIILLVF
40 50 60 70 80 90
230 240 250 260 270 280
pF1KE6 IRELKNLFVLSFLANVSMAVSLVIIYQYVVRNMPDPHNLPIVAGWKKYPLFFGTAVFAFE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IRELKNLFVLSFLANVSMAVSLVIIYQYVVRNMPDPHNLPIVAGWKKYPLFFGTAVFAFE
100 110 120 130 140 150
290 300 310 320 330 340
pF1KE6 GIGVVLPLENQMKESKRFPQALNIGMGIVTTLYVTLATLGYMCFHDEIKGSITLNLPQDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GIGVVLPLENQMKESKRFPQALNIGMGIVTTLYVTLATLGYMCFHDEIKGSITLNLPQDV
160 170 180 190 200 210
350 360 370 380 390 400
pF1KE6 WLYQSVKILYSFGIFVTYSIQFYVPAEIIIHGITSKFHTKWKQICEFGIRSFLVSITCAG
:::::::::::::::::::::::::::::: :::::::::::::::::::::::::::::
NP_001 WLYQSVKILYSFGIFVTYSIQFYVPAEIIIPGITSKFHTKWKQICEFGIRSFLVSITCAG
220 230 240 250 260 270
410 420 430 440 450 460
pF1KE6 AILIPRLDIVISFVGAVSSSTLAIILPPLVEILTFSKEHYNIWMVLKNISIAFTGVVGFL
:::::::::::::::::::::::.::::::::::::::::::::::::::::::::::::
NP_001 AILIPRLDIVISFVGAVSSSTLALILPPLVEILTFSKEHYNIWMVLKNISIAFTGVVGFL
280 290 300 310 320 330
470 480 490 500
pF1KE6 LGTYITVEEIIYPTPKVVAGTPQSPFLNLNSTCLTSGLK
:::::::::::::::::::::::::::::::::::::::
NP_001 LGTYITVEEIIYPTPKVVAGTPQSPFLNLNSTCLTSGLK
340 350 360
>>XP_016872665 (OMIM: 613760) PREDICTED: proton-coupled (369 aa)
initn: 2399 init1: 2399 opt: 2399 Z-score: 2885.3 bits: 543.0 E(85289): 5.7e-154
Smith-Waterman score: 2399; 99.2% identity (99.7% similar) in 369 aa overlap (136-504:1-369)
110 120 130 140 150 160
pF1KE6 CMHILVRCSHFLCLRFKKSTLGYSDTVSFAMEVSPWSCLQKQAAWGRSVVDFFLVITQLG
::::::::::::::::::::::::::::::
XP_016 MEVSPWSCLQKQAAWGRSVVDFFLVITQLG
10 20 30
170 180 190 200 210 220
pF1KE6 FCSVYIVFLAENVKQVHEGFLESKVFISNSTNSSNPCERRSVDIRIYMLCFLPFIILLVF
:::::::::::::::::::::::::::::::::::::::::::.::::::::::::::::
XP_016 FCSVYIVFLAENVKQVHEGFLESKVFISNSTNSSNPCERRSVDLRIYMLCFLPFIILLVF
40 50 60 70 80 90
230 240 250 260 270 280
pF1KE6 IRELKNLFVLSFLANVSMAVSLVIIYQYVVRNMPDPHNLPIVAGWKKYPLFFGTAVFAFE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IRELKNLFVLSFLANVSMAVSLVIIYQYVVRNMPDPHNLPIVAGWKKYPLFFGTAVFAFE
100 110 120 130 140 150
290 300 310 320 330 340
pF1KE6 GIGVVLPLENQMKESKRFPQALNIGMGIVTTLYVTLATLGYMCFHDEIKGSITLNLPQDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GIGVVLPLENQMKESKRFPQALNIGMGIVTTLYVTLATLGYMCFHDEIKGSITLNLPQDV
160 170 180 190 200 210
350 360 370 380 390 400
pF1KE6 WLYQSVKILYSFGIFVTYSIQFYVPAEIIIHGITSKFHTKWKQICEFGIRSFLVSITCAG
:::::::::::::::::::::::::::::: :::::::::::::::::::::::::::::
XP_016 WLYQSVKILYSFGIFVTYSIQFYVPAEIIIPGITSKFHTKWKQICEFGIRSFLVSITCAG
220 230 240 250 260 270
410 420 430 440 450 460
pF1KE6 AILIPRLDIVISFVGAVSSSTLAIILPPLVEILTFSKEHYNIWMVLKNISIAFTGVVGFL
:::::::::::::::::::::::.::::::::::::::::::::::::::::::::::::
XP_016 AILIPRLDIVISFVGAVSSSTLALILPPLVEILTFSKEHYNIWMVLKNISIAFTGVVGFL
280 290 300 310 320 330
470 480 490 500
pF1KE6 LGTYITVEEIIYPTPKVVAGTPQSPFLNLNSTCLTSGLK
:::::::::::::::::::::::::::::::::::::::
XP_016 LGTYITVEEIIYPTPKVVAGTPQSPFLNLNSTCLTSGLK
340 350 360
>>XP_016872666 (OMIM: 613760) PREDICTED: proton-coupled (272 aa)
initn: 1741 init1: 1741 opt: 1741 Z-score: 2096.8 bits: 396.6 E(85289): 4.7e-110
Smith-Waterman score: 1741; 99.2% identity (99.6% similar) in 264 aa overlap (136-399:1-264)
110 120 130 140 150 160
pF1KE6 CMHILVRCSHFLCLRFKKSTLGYSDTVSFAMEVSPWSCLQKQAAWGRSVVDFFLVITQLG
::::::::::::::::::::::::::::::
XP_016 MEVSPWSCLQKQAAWGRSVVDFFLVITQLG
10 20 30
170 180 190 200 210 220
pF1KE6 FCSVYIVFLAENVKQVHEGFLESKVFISNSTNSSNPCERRSVDIRIYMLCFLPFIILLVF
:::::::::::::::::::::::::::::::::::::::::::.::::::::::::::::
XP_016 FCSVYIVFLAENVKQVHEGFLESKVFISNSTNSSNPCERRSVDLRIYMLCFLPFIILLVF
40 50 60 70 80 90
230 240 250 260 270 280
pF1KE6 IRELKNLFVLSFLANVSMAVSLVIIYQYVVRNMPDPHNLPIVAGWKKYPLFFGTAVFAFE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IRELKNLFVLSFLANVSMAVSLVIIYQYVVRNMPDPHNLPIVAGWKKYPLFFGTAVFAFE
100 110 120 130 140 150
290 300 310 320 330 340
pF1KE6 GIGVVLPLENQMKESKRFPQALNIGMGIVTTLYVTLATLGYMCFHDEIKGSITLNLPQDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GIGVVLPLENQMKESKRFPQALNIGMGIVTTLYVTLATLGYMCFHDEIKGSITLNLPQDV
160 170 180 190 200 210
350 360 370 380 390 400
pF1KE6 WLYQSVKILYSFGIFVTYSIQFYVPAEIIIHGITSKFHTKWKQICEFGIRSFLVSITCAG
:::::::::::::::::::::::::::::: :::::::::::::::::::::::
XP_016 WLYQSVKILYSFGIFVTYSIQFYVPAEIIIPGITSKFHTKWKQICEFGIRSFLVPEQFLF
220 230 240 250 260 270
410 420 430 440 450 460
pF1KE6 AILIPRLDIVISFVGAVSSSTLAIILPPLVEILTFSKEHYNIWMVLKNISIAFTGVVGFL
XP_016 LV
>>XP_011535887 (OMIM: 606561) PREDICTED: proton-coupled (476 aa)
initn: 1579 init1: 602 opt: 1593 Z-score: 1915.6 bits: 363.9 E(85289): 5.8e-100
Smith-Waterman score: 1599; 55.0% identity (80.2% similar) in 449 aa overlap (51-498:38-473)
30 40 50 60 70
pF1KE6 DVMRPLINEQNFDGTSDEEHEQELLPVQKHYQ-LDDQEGISFVQTLMHLLKGNIGTGLLG
:: . .... .. :::.:::::::::::::
XP_011 NEDYHDYSSTDVSPEESPSEGLNNLSSPGSYQRFGQSNSTTWFQTLIHLLKGNIGTGLLG
10 20 30 40 50 60
80 90 100 110 120 130
pF1KE6 LPLAIKNAGIVLGPISLVFIGIISVHCMHILVRCSHFLCLRFKKSTLGYSDTVSFAMEVS
::::.::::::.:::::..:::..:::: :::.:.: .: :..:: . :.::: ...: :
XP_011 LPLAVKNAGIVMGPISLLIIGIVAVHCMGILVKCAHHFCRRLNKSFVDYGDTVMYGLESS
70 80 90 100 110 120
140 150 160 170 180 190
pF1KE6 PWSCLQKQAAWGRSVVDFFLVITQLGFCSVYIVFLAENVKQVHEGFLESKVFISNSTNSS
: : :...: ::: ::::::..:::::: ::.::::.: ::: :. .. .: :.
XP_011 PCSWLRNHAHWGRRVVDFFLIVTQLGFCCVYFVFLADNFKQVIEA---ANGTTNNCHNNE
130 140 150 160 170 180
200 210 220 230 240 250
pF1KE6 NPCERRSVDIRIYMLCFLPFIILLVFIRELKNLFVLSFLANVSMAVSLVIIYQYVVRNMP
. ..: :.::: ::::..::::::.:. : ..:.:::..: ::::.:::..:. .:
XP_011 TVILTPTMDSRLYMLSFLPFLVLLVFIRNLRALSIFSLLANITMLVSLVMIYQFIVQRIP
190 200 210 220 230 240
260 270 280 290 300 310
pF1KE6 DPHNLPIVAGWKKYPLFFGTAVFAFEGIGVVLPLENQMKESKRFPQALNIGMGIVTTLYV
:: .::.:: :: ::::::::.:.:::::.::::::.::. ..:: : .:: ::: ::.
XP_011 DPSHLPLVAPWKTYPLFFGTAIFSFEGIGMVLPLENKMKDPRKFPLILYLGMVIVTILYI
250 260 270 280 290 300
320 330 340 350 360 370
pF1KE6 TLATLGYMCFHDEIKGSITLNLPQDVWLYQSVKILYSFGIFVTYSIQFYVPAEIIIHGIT
.:. :::. : .:.:::::::: . :::::::.:::.::: ::..:::::::::: ..
XP_011 SLGCLGYLQFGANIQGSITLNLP-NCWLYQSVKLLYSIGIFFTYALQFYVPAEIIIPFFV
310 320 330 340 350 360
380 390 400 410 420 430
pF1KE6 SKFHTKWKQICEFGIRSFLVSITCAGAILIPRLDIVISFVGAVSSSTLAIILPPLVEILT
:. . . . .. .:. :: .:: ::::::::.:::.::.::::.::.:.:::.:. :
XP_011 SRAPEHCELVVDLFVRTVLVCLTCILAILIPRLDLVISLVGSVSSSALALIIPPLLEVTT
370 380 390 400 410 420
440 450 460 470 480 490
pF1KE6 FSKEHYNIWMVLKNISIAFTGVVGFLLGTYITVEEIIYPTPKVVAGTPQSPFLNLNSTCL
: .: .. ..:. :.. : :::..::: .. :.: :. ..:.. .::::
XP_011 FYSEGMSPLTIFKDALISILGFVGFVVGTYEALYELIQPS--------NAPIF-INSTCA
430 440 450 460 470
500
pF1KE6 TSGLK
XP_011 FI
>>XP_011535889 (OMIM: 606561) PREDICTED: proton-coupled (476 aa)
initn: 1579 init1: 602 opt: 1593 Z-score: 1915.6 bits: 363.9 E(85289): 5.8e-100
Smith-Waterman score: 1599; 55.0% identity (80.2% similar) in 449 aa overlap (51-498:38-473)
30 40 50 60 70
pF1KE6 DVMRPLINEQNFDGTSDEEHEQELLPVQKHYQ-LDDQEGISFVQTLMHLLKGNIGTGLLG
:: . .... .. :::.:::::::::::::
XP_011 NEDYHDYSSTDVSPEESPSEGLNNLSSPGSYQRFGQSNSTTWFQTLIHLLKGNIGTGLLG
10 20 30 40 50 60
80 90 100 110 120 130
pF1KE6 LPLAIKNAGIVLGPISLVFIGIISVHCMHILVRCSHFLCLRFKKSTLGYSDTVSFAMEVS
::::.::::::.:::::..:::..:::: :::.:.: .: :..:: . :.::: ...: :
XP_011 LPLAVKNAGIVMGPISLLIIGIVAVHCMGILVKCAHHFCRRLNKSFVDYGDTVMYGLESS
70 80 90 100 110 120
140 150 160 170 180 190
pF1KE6 PWSCLQKQAAWGRSVVDFFLVITQLGFCSVYIVFLAENVKQVHEGFLESKVFISNSTNSS
: : :...: ::: ::::::..:::::: ::.::::.: ::: :. .. .: :.
XP_011 PCSWLRNHAHWGRRVVDFFLIVTQLGFCCVYFVFLADNFKQVIEA---ANGTTNNCHNNE
130 140 150 160 170 180
200 210 220 230 240 250
pF1KE6 NPCERRSVDIRIYMLCFLPFIILLVFIRELKNLFVLSFLANVSMAVSLVIIYQYVVRNMP
. ..: :.::: ::::..::::::.:. : ..:.:::..: ::::.:::..:. .:
XP_011 TVILTPTMDSRLYMLSFLPFLVLLVFIRNLRALSIFSLLANITMLVSLVMIYQFIVQRIP
190 200 210 220 230 240
260 270 280 290 300 310
pF1KE6 DPHNLPIVAGWKKYPLFFGTAVFAFEGIGVVLPLENQMKESKRFPQALNIGMGIVTTLYV
:: .::.:: :: ::::::::.:.:::::.::::::.::. ..:: : .:: ::: ::.
XP_011 DPSHLPLVAPWKTYPLFFGTAIFSFEGIGMVLPLENKMKDPRKFPLILYLGMVIVTILYI
250 260 270 280 290 300
320 330 340 350 360 370
pF1KE6 TLATLGYMCFHDEIKGSITLNLPQDVWLYQSVKILYSFGIFVTYSIQFYVPAEIIIHGIT
.:. :::. : .:.:::::::: . :::::::.:::.::: ::..:::::::::: ..
XP_011 SLGCLGYLQFGANIQGSITLNLP-NCWLYQSVKLLYSIGIFFTYALQFYVPAEIIIPFFV
310 320 330 340 350 360
380 390 400 410 420 430
pF1KE6 SKFHTKWKQICEFGIRSFLVSITCAGAILIPRLDIVISFVGAVSSSTLAIILPPLVEILT
:. . . . .. .:. :: .:: ::::::::.:::.::.::::.::.:.:::.:. :
XP_011 SRAPEHCELVVDLFVRTVLVCLTCILAILIPRLDLVISLVGSVSSSALALIIPPLLEVTT
370 380 390 400 410 420
440 450 460 470 480 490
pF1KE6 FSKEHYNIWMVLKNISIAFTGVVGFLLGTYITVEEIIYPTPKVVAGTPQSPFLNLNSTCL
: .: .. ..:. :.. : :::..::: .. :.: :. ..:.. .::::
XP_011 FYSEGMSPLTIFKDALISILGFVGFVVGTYEALYELIQPS--------NAPIF-INSTCA
430 440 450 460 470
500
pF1KE6 TSGLK
XP_011 FI
>>XP_011535891 (OMIM: 606561) PREDICTED: proton-coupled (476 aa)
initn: 1579 init1: 602 opt: 1593 Z-score: 1915.6 bits: 363.9 E(85289): 5.8e-100
Smith-Waterman score: 1599; 55.0% identity (80.2% similar) in 449 aa overlap (51-498:38-473)
30 40 50 60 70
pF1KE6 DVMRPLINEQNFDGTSDEEHEQELLPVQKHYQ-LDDQEGISFVQTLMHLLKGNIGTGLLG
:: . .... .. :::.:::::::::::::
XP_011 NEDYHDYSSTDVSPEESPSEGLNNLSSPGSYQRFGQSNSTTWFQTLIHLLKGNIGTGLLG
10 20 30 40 50 60
80 90 100 110 120 130
pF1KE6 LPLAIKNAGIVLGPISLVFIGIISVHCMHILVRCSHFLCLRFKKSTLGYSDTVSFAMEVS
::::.::::::.:::::..:::..:::: :::.:.: .: :..:: . :.::: ...: :
XP_011 LPLAVKNAGIVMGPISLLIIGIVAVHCMGILVKCAHHFCRRLNKSFVDYGDTVMYGLESS
70 80 90 100 110 120
140 150 160 170 180 190
pF1KE6 PWSCLQKQAAWGRSVVDFFLVITQLGFCSVYIVFLAENVKQVHEGFLESKVFISNSTNSS
: : :...: ::: ::::::..:::::: ::.::::.: ::: :. .. .: :.
XP_011 PCSWLRNHAHWGRRVVDFFLIVTQLGFCCVYFVFLADNFKQVIEA---ANGTTNNCHNNE
130 140 150 160 170 180
200 210 220 230 240 250
pF1KE6 NPCERRSVDIRIYMLCFLPFIILLVFIRELKNLFVLSFLANVSMAVSLVIIYQYVVRNMP
. ..: :.::: ::::..::::::.:. : ..:.:::..: ::::.:::..:. .:
XP_011 TVILTPTMDSRLYMLSFLPFLVLLVFIRNLRALSIFSLLANITMLVSLVMIYQFIVQRIP
190 200 210 220 230 240
260 270 280 290 300 310
pF1KE6 DPHNLPIVAGWKKYPLFFGTAVFAFEGIGVVLPLENQMKESKRFPQALNIGMGIVTTLYV
:: .::.:: :: ::::::::.:.:::::.::::::.::. ..:: : .:: ::: ::.
XP_011 DPSHLPLVAPWKTYPLFFGTAIFSFEGIGMVLPLENKMKDPRKFPLILYLGMVIVTILYI
250 260 270 280 290 300
320 330 340 350 360 370
pF1KE6 TLATLGYMCFHDEIKGSITLNLPQDVWLYQSVKILYSFGIFVTYSIQFYVPAEIIIHGIT
.:. :::. : .:.:::::::: . :::::::.:::.::: ::..:::::::::: ..
XP_011 SLGCLGYLQFGANIQGSITLNLP-NCWLYQSVKLLYSIGIFFTYALQFYVPAEIIIPFFV
310 320 330 340 350 360
380 390 400 410 420 430
pF1KE6 SKFHTKWKQICEFGIRSFLVSITCAGAILIPRLDIVISFVGAVSSSTLAIILPPLVEILT
:. . . . .. .:. :: .:: ::::::::.:::.::.::::.::.:.:::.:. :
XP_011 SRAPEHCELVVDLFVRTVLVCLTCILAILIPRLDLVISLVGSVSSSALALIIPPLLEVTT
370 380 390 400 410 420
440 450 460 470 480 490
pF1KE6 FSKEHYNIWMVLKNISIAFTGVVGFLLGTYITVEEIIYPTPKVVAGTPQSPFLNLNSTCL
: .: .. ..:. :.. : :::..::: .. :.: :. ..:.. .::::
XP_011 FYSEGMSPLTIFKDALISILGFVGFVVGTYEALYELIQPS--------NAPIF-INSTCA
430 440 450 460 470
500
pF1KE6 TSGLK
XP_011 FI
>>XP_011535888 (OMIM: 606561) PREDICTED: proton-coupled (476 aa)
initn: 1579 init1: 602 opt: 1593 Z-score: 1915.6 bits: 363.9 E(85289): 5.8e-100
Smith-Waterman score: 1599; 55.0% identity (80.2% similar) in 449 aa overlap (51-498:38-473)
30 40 50 60 70
pF1KE6 DVMRPLINEQNFDGTSDEEHEQELLPVQKHYQ-LDDQEGISFVQTLMHLLKGNIGTGLLG
:: . .... .. :::.:::::::::::::
XP_011 NEDYHDYSSTDVSPEESPSEGLNNLSSPGSYQRFGQSNSTTWFQTLIHLLKGNIGTGLLG
10 20 30 40 50 60
80 90 100 110 120 130
pF1KE6 LPLAIKNAGIVLGPISLVFIGIISVHCMHILVRCSHFLCLRFKKSTLGYSDTVSFAMEVS
::::.::::::.:::::..:::..:::: :::.:.: .: :..:: . :.::: ...: :
XP_011 LPLAVKNAGIVMGPISLLIIGIVAVHCMGILVKCAHHFCRRLNKSFVDYGDTVMYGLESS
70 80 90 100 110 120
140 150 160 170 180 190
pF1KE6 PWSCLQKQAAWGRSVVDFFLVITQLGFCSVYIVFLAENVKQVHEGFLESKVFISNSTNSS
: : :...: ::: ::::::..:::::: ::.::::.: ::: :. .. .: :.
XP_011 PCSWLRNHAHWGRRVVDFFLIVTQLGFCCVYFVFLADNFKQVIEA---ANGTTNNCHNNE
130 140 150 160 170 180
200 210 220 230 240 250
pF1KE6 NPCERRSVDIRIYMLCFLPFIILLVFIRELKNLFVLSFLANVSMAVSLVIIYQYVVRNMP
. ..: :.::: ::::..::::::.:. : ..:.:::..: ::::.:::..:. .:
XP_011 TVILTPTMDSRLYMLSFLPFLVLLVFIRNLRALSIFSLLANITMLVSLVMIYQFIVQRIP
190 200 210 220 230 240
260 270 280 290 300 310
pF1KE6 DPHNLPIVAGWKKYPLFFGTAVFAFEGIGVVLPLENQMKESKRFPQALNIGMGIVTTLYV
:: .::.:: :: ::::::::.:.:::::.::::::.::. ..:: : .:: ::: ::.
XP_011 DPSHLPLVAPWKTYPLFFGTAIFSFEGIGMVLPLENKMKDPRKFPLILYLGMVIVTILYI
250 260 270 280 290 300
320 330 340 350 360 370
pF1KE6 TLATLGYMCFHDEIKGSITLNLPQDVWLYQSVKILYSFGIFVTYSIQFYVPAEIIIHGIT
.:. :::. : .:.:::::::: . :::::::.:::.::: ::..:::::::::: ..
XP_011 SLGCLGYLQFGANIQGSITLNLP-NCWLYQSVKLLYSIGIFFTYALQFYVPAEIIIPFFV
310 320 330 340 350 360
380 390 400 410 420 430
pF1KE6 SKFHTKWKQICEFGIRSFLVSITCAGAILIPRLDIVISFVGAVSSSTLAIILPPLVEILT
:. . . . .. .:. :: .:: ::::::::.:::.::.::::.::.:.:::.:. :
XP_011 SRAPEHCELVVDLFVRTVLVCLTCILAILIPRLDLVISLVGSVSSSALALIIPPLLEVTT
370 380 390 400 410 420
440 450 460 470 480 490
pF1KE6 FSKEHYNIWMVLKNISIAFTGVVGFLLGTYITVEEIIYPTPKVVAGTPQSPFLNLNSTCL
: .: .. ..:. :.. : :::..::: .. :.: :. ..:.. .::::
XP_011 FYSEGMSPLTIFKDALISILGFVGFVVGTYEALYELIQPS--------NAPIF-INSTCA
430 440 450 460 470
500
pF1KE6 TSGLK
XP_011 FI
504 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Nov 8 13:36:48 2016 done: Tue Nov 8 13:36:49 2016
Total Scan time: 5.340 Total Display time: 0.030
Function used was FASTA [36.3.4 Apr, 2011]