Result of FASTA (omim) for
pFN21AE6469
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE6469, 530 aa
1>>>pF1KE6469 530 - 530 aa - 530 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.0330+/-0.000537; mu= 14.2174+/- 0.033
mean_var=74.0940+/-14.158, 0's: 0 Z-trim(106.7): 53 B-trim: 0 in 0/50
Lambda= 0.148999
statistics sampled from 14761 (14793) to 14761 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.518), E-opt: 0.2 (0.173), width: 16
Scan time: 5.990
The best scores are: opt bits E(85289)
NP_006575 (OMIM: 610730) T-complex protein 1 subun ( 530) 3350 730.4 3.3e-210
NP_001753 (OMIM: 104613) T-complex protein 1 subun ( 531) 2959 646.3 6.5e-185
XP_016879512 (OMIM: 610730) PREDICTED: T-complex p ( 464) 2956 645.7 9e-185
NP_001180459 (OMIM: 610730) T-complex protein 1 su ( 485) 2688 588.1 2.1e-167
XP_011522505 (OMIM: 610730) PREDICTED: T-complex p ( 388) 2495 546.5 5.2e-155
NP_001009186 (OMIM: 104613) T-complex protein 1 su ( 486) 2330 511.1 3e-144
XP_016879513 (OMIM: 610730) PREDICTED: T-complex p ( 351) 1860 410.0 5.9e-114
NP_001180458 (OMIM: 610730) T-complex protein 1 su ( 493) 1860 410.1 8e-114
NP_005989 (OMIM: 600114) T-complex protein 1 subun ( 545) 890 201.6 5.1e-51
NP_036205 (OMIM: 256840,610150) T-complex protein ( 541) 847 192.3 3.1e-48
NP_001293082 (OMIM: 256840,610150) T-complex prote ( 520) 840 190.8 8.4e-48
NP_001293085 (OMIM: 256840,610150) T-complex prote ( 503) 836 190.0 1.5e-47
NP_006421 (OMIM: 605142) T-complex protein 1 subun ( 539) 815 185.5 3.6e-46
NP_001008800 (OMIM: 600114) T-complex protein 1 su ( 507) 755 172.6 2.6e-42
NP_110379 (OMIM: 186980) T-complex protein 1 subun ( 556) 741 169.6 2.3e-41
NP_006420 (OMIM: 605140) T-complex protein 1 subun ( 543) 670 154.3 8.8e-37
NP_001293083 (OMIM: 256840,610150) T-complex prote ( 486) 638 147.4 9.3e-35
NP_001293084 (OMIM: 256840,610150) T-complex prote ( 448) 634 146.5 1.6e-34
NP_001243650 (OMIM: 605142) T-complex protein 1 su ( 509) 626 144.8 5.8e-34
NP_006422 (OMIM: 605139) T-complex protein 1 subun ( 535) 614 142.3 3.6e-33
NP_001159757 (OMIM: 605140) T-complex protein 1 su ( 499) 610 141.4 6.2e-33
XP_011530780 (OMIM: 605140) PREDICTED: T-complex p ( 499) 610 141.4 6.2e-33
XP_011530781 (OMIM: 605140) PREDICTED: T-complex p ( 499) 610 141.4 6.2e-33
NP_001185771 (OMIM: 605139) T-complex protein 1 su ( 488) 542 126.8 1.5e-28
NP_001159756 (OMIM: 605140) T-complex protein 1 su ( 456) 519 121.8 4.4e-27
NP_001008897 (OMIM: 186980) T-complex protein 1 su ( 401) 487 114.9 4.6e-25
NP_001009570 (OMIM: 605140) T-complex protein 1 su ( 339) 404 97.0 9.4e-20
NP_078961 (OMIM: 610148,615987) Bardet-Biedl syndr ( 723) 157 44.1 0.0018
NP_955472 (OMIM: 118190,605280,612233) 60 kDa heat ( 573) 146 41.7 0.0074
NP_002147 (OMIM: 118190,605280,612233) 60 kDa heat ( 573) 146 41.7 0.0074
>>NP_006575 (OMIM: 610730) T-complex protein 1 subunit z (530 aa)
initn: 3350 init1: 3350 opt: 3350 Z-score: 3895.0 bits: 730.4 E(85289): 3.3e-210
Smith-Waterman score: 3350; 99.6% identity (100.0% similar) in 530 aa overlap (1-530:1-530)
10 20 30 40 50 60
pF1KE6 MAAIKAVNSKAEVARAQAALAVNICAARGLQDVLRTNLGPKGTMKMLASGAGDIKLTKDG
::::::::::::::::.::::::::::::::::::::::::::::::.::::::::::::
NP_006 MAAIKAVNSKAEVARARAALAVNICAARGLQDVLRTNLGPKGTMKMLVSGAGDIKLTKDG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 NVLLDEMQIQHPTASLIAKVATAQDDVTGDGTTSNVLIIGELLKQADLYISEGLHPRIIA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 NVLLDEMQIQHPTASLIAKVATAQDDVTGDGTTSNVLIIGELLKQADLYISEGLHPRIIA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 EGFEAAKIKALEVLEEVKVTKEMKRKILLDVARTSLQTKVHAELADVLTEVVVDSVLAVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 EGFEAAKIKALEVLEEVKVTKEMKRKILLDVARTSLQTKVHAELADVLTEVVVDSVLAVR
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE6 RPGYPIDLFMVEIMEMKHKLGTDTKLIQGLVLDHGARHPDMKKRVEDAFILICNVSLEYE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 RPGYPIDLFMVEIMEMKHKLGTDTKLIQGLVLDHGARHPDMKKRVEDAFILICNVSLEYE
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE6 KTEVNSGFFYKTAEEKEKLVKAERKFIEDRVQKIIDLKDKVCAQSNKGFVVINQKGIDPF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 KTEVNSGFFYKTAEEKEKLVKAERKFIEDRVQKIIDLKDKVCAQSNKGFVVINQKGIDPF
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE6 SLDSLAKHGIVALRRAKRRNMERLSLACGGMAVNSFEDLTVDCLGHAGLVYEYTLGEEKF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 SLDSLAKHGIVALRRAKRRNMERLSLACGGMAVNSFEDLTVDCLGHAGLVYEYTLGEEKF
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE6 TFIEECVNPCSVTLLVKGPNKHTLTQVKDAIRDGLRAIKNAIEDGCMVPGAGAIEVAMAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 TFIEECVNPCSVTLLVKGPNKHTLTQVKDAIRDGLRAIKNAIEDGCMVPGAGAIEVAMAE
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE6 ALVTYKNSIKGRARLGVQAFADALLIIPKVLAQNAGYDPQETLVKVQAEHVESKQLVGVD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 ALVTYKNSIKGRARLGVQAFADALLIIPKVLAQNAGYDPQETLVKVQAEHVESKQLVGVD
430 440 450 460 470 480
490 500 510 520 530
pF1KE6 LNTGEPMVAADAGVWDNYCVKKQLLHSCTVIATNILLVDEIMRAGMSSLK
::::::::::::::::::::::::::::::::::::::::::::::::::
NP_006 LNTGEPMVAADAGVWDNYCVKKQLLHSCTVIATNILLVDEIMRAGMSSLK
490 500 510 520 530
>>NP_001753 (OMIM: 104613) T-complex protein 1 subunit z (531 aa)
initn: 2959 init1: 2959 opt: 2959 Z-score: 3440.7 bits: 646.3 E(85289): 6.5e-185
Smith-Waterman score: 2959; 85.8% identity (95.8% similar) in 530 aa overlap (1-530:1-530)
10 20 30 40 50 60
pF1KE6 MAAIKAVNSKAEVARAQAALAVNICAARGLQDVLRTNLGPKGTMKMLASGAGDIKLTKDG
:::.:..: ::::::::::::::: ::::::::::::::::::::::.::::::::::::
NP_001 MAAVKTLNPKAEVARAQAALAVNISAARGLQDVLRTNLGPKGTMKMLVSGAGDIKLTKDG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 NVLLDEMQIQHPTASLIAKVATAQDDVTGDGTTSNVLIIGELLKQADLYISEGLHPRIIA
:::: :::::::::::::::::::::.::::::::::::::::::::::::::::::::.
NP_001 NVLLHEMQIQHPTASLIAKVATAQDDITGDGTTSNVLIIGELLKQADLYISEGLHPRIIT
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 EGFEAAKIKALEVLEEVKVTKEMKRKILLDVARTSLQTKVHAELADVLTEVVVDSVLAVR
::::::: :::. ::::::..:: :. :.:::::::.:::::::::::::.::::.::..
NP_001 EGFEAAKEKALQFLEEVKVSREMDRETLIDVARTSLRTKVHAELADVLTEAVVDSILAIK
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE6 RPGYPIDLFMVEIMEMKHKLGTDTKLIQGLVLDHGARHPDMKKRVEDAFILICNVSLEYE
. ::::::.:::::::: :::.::.::::::::::::::::::::.:: ::::::::
NP_001 KQDEPIDLFMIEIMEMKHKSETDTSLIRGLVLDHGARHPDMKKRVEDAYILTCNVSLEYE
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE6 KTEVNSGFFYKTAEEKEKLVKAERKFIEDRVQKIIDLKDKVCAQSNKGFVVINQKGIDPF
:::::::::::.:::.:::::::::::::::.:::.:: :::..:.::::::::::::::
NP_001 KTEVNSGFFYKSAEEREKLVKAERKFIEDRVKKIIELKRKVCGDSDKGFVVINQKGIDPF
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE6 SLDSLAKHGIVALRRAKRRNMERLSLACGGMAVNSFEDLTVDCLGHAGLVYEYTLGEEKF
:::.:.:.::::::::::::::::.:::::.:.:::.::. :::::::::::::::::::
NP_001 SLDALSKEGIVALRRAKRRNMERLTLACGGVALNSFDDLSPDCLGHAGLVYEYTLGEEKF
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE6 TFIEECVNPCSVTLLVKGPNKHTLTQVKDAIRDGLRAIKNAIEDGCMVPGAGAIEVAMAE
::::.: :: :::::.::::::::::.:::.::::::.::::.:::.::::::.::::::
NP_001 TFIEKCNNPRSVTLLIKGPNKHTLTQIKDAVRDGLRAVKNAIDDGCVVPGAGAVEVAMAE
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE6 ALVTYKNSIKGRARLGVQAFADALLIIPKVLAQNAGYDPQETLVKVQAEHVESKQLVGVD
::. .: :.::::.::::::::::::::::::::.:.: ::::::.:::: :: ::::::
NP_001 ALIKHKPSVKGRAQLGVQAFADALLIIPKVLAQNSGFDLQETLVKIQAEHSESGQLVGVD
430 440 450 460 470 480
490 500 510 520 530
pF1KE6 LNTGEPMVAADAGVWDNYCVKKQLLHSCTVIATNILLVDEIMRAGMSSLK
::::::::::..::::::::::::::::::::::::::::::::::::::
NP_001 LNTGEPMVAAEVGVWDNYCVKKQLLHSCTVIATNILLVDEIMRAGMSSLKG
490 500 510 520 530
>>XP_016879512 (OMIM: 610730) PREDICTED: T-complex prote (464 aa)
initn: 2956 init1: 2956 opt: 2956 Z-score: 3438.2 bits: 645.7 E(85289): 9e-185
Smith-Waterman score: 2956; 100.0% identity (100.0% similar) in 464 aa overlap (67-530:1-464)
40 50 60 70 80 90
pF1KE6 NLGPKGTMKMLASGAGDIKLTKDGNVLLDEMQIQHPTASLIAKVATAQDDVTGDGTTSNV
::::::::::::::::::::::::::::::
XP_016 MQIQHPTASLIAKVATAQDDVTGDGTTSNV
10 20 30
100 110 120 130 140 150
pF1KE6 LIIGELLKQADLYISEGLHPRIIAEGFEAAKIKALEVLEEVKVTKEMKRKILLDVARTSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LIIGELLKQADLYISEGLHPRIIAEGFEAAKIKALEVLEEVKVTKEMKRKILLDVARTSL
40 50 60 70 80 90
160 170 180 190 200 210
pF1KE6 QTKVHAELADVLTEVVVDSVLAVRRPGYPIDLFMVEIMEMKHKLGTDTKLIQGLVLDHGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 QTKVHAELADVLTEVVVDSVLAVRRPGYPIDLFMVEIMEMKHKLGTDTKLIQGLVLDHGA
100 110 120 130 140 150
220 230 240 250 260 270
pF1KE6 RHPDMKKRVEDAFILICNVSLEYEKTEVNSGFFYKTAEEKEKLVKAERKFIEDRVQKIID
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RHPDMKKRVEDAFILICNVSLEYEKTEVNSGFFYKTAEEKEKLVKAERKFIEDRVQKIID
160 170 180 190 200 210
280 290 300 310 320 330
pF1KE6 LKDKVCAQSNKGFVVINQKGIDPFSLDSLAKHGIVALRRAKRRNMERLSLACGGMAVNSF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LKDKVCAQSNKGFVVINQKGIDPFSLDSLAKHGIVALRRAKRRNMERLSLACGGMAVNSF
220 230 240 250 260 270
340 350 360 370 380 390
pF1KE6 EDLTVDCLGHAGLVYEYTLGEEKFTFIEECVNPCSVTLLVKGPNKHTLTQVKDAIRDGLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EDLTVDCLGHAGLVYEYTLGEEKFTFIEECVNPCSVTLLVKGPNKHTLTQVKDAIRDGLR
280 290 300 310 320 330
400 410 420 430 440 450
pF1KE6 AIKNAIEDGCMVPGAGAIEVAMAEALVTYKNSIKGRARLGVQAFADALLIIPKVLAQNAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AIKNAIEDGCMVPGAGAIEVAMAEALVTYKNSIKGRARLGVQAFADALLIIPKVLAQNAG
340 350 360 370 380 390
460 470 480 490 500 510
pF1KE6 YDPQETLVKVQAEHVESKQLVGVDLNTGEPMVAADAGVWDNYCVKKQLLHSCTVIATNIL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YDPQETLVKVQAEHVESKQLVGVDLNTGEPMVAADAGVWDNYCVKKQLLHSCTVIATNIL
400 410 420 430 440 450
520 530
pF1KE6 LVDEIMRAGMSSLK
::::::::::::::
XP_016 LVDEIMRAGMSSLK
460
>>NP_001180459 (OMIM: 610730) T-complex protein 1 subuni (485 aa)
initn: 2676 init1: 2676 opt: 2688 Z-score: 3126.6 bits: 588.1 E(85289): 2.1e-167
Smith-Waterman score: 2977; 91.1% identity (91.5% similar) in 530 aa overlap (1-530:1-485)
10 20 30 40 50 60
pF1KE6 MAAIKAVNSKAEVARAQAALAVNICAARGLQDVLRTNLGPKGTMKMLASGAGDIKLTKDG
::::::::::::::::.::::::::::::::::::::::::::::::.::::::::::::
NP_001 MAAIKAVNSKAEVARARAALAVNICAARGLQDVLRTNLGPKGTMKMLVSGAGDIKLTKDG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 NVLLDEMQIQHPTASLIAKVATAQDDVTGDGTTSNVLIIGELLKQADLYISEGLHPRIIA
::::::: ::::::::
NP_001 NVLLDEM---------------------------------------------GLHPRIIA
70
130 140 150 160 170 180
pF1KE6 EGFEAAKIKALEVLEEVKVTKEMKRKILLDVARTSLQTKVHAELADVLTEVVVDSVLAVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EGFEAAKIKALEVLEEVKVTKEMKRKILLDVARTSLQTKVHAELADVLTEVVVDSVLAVR
80 90 100 110 120 130
190 200 210 220 230 240
pF1KE6 RPGYPIDLFMVEIMEMKHKLGTDTKLIQGLVLDHGARHPDMKKRVEDAFILICNVSLEYE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RPGYPIDLFMVEIMEMKHKLGTDTKLIQGLVLDHGARHPDMKKRVEDAFILICNVSLEYE
140 150 160 170 180 190
250 260 270 280 290 300
pF1KE6 KTEVNSGFFYKTAEEKEKLVKAERKFIEDRVQKIIDLKDKVCAQSNKGFVVINQKGIDPF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KTEVNSGFFYKTAEEKEKLVKAERKFIEDRVQKIIDLKDKVCAQSNKGFVVINQKGIDPF
200 210 220 230 240 250
310 320 330 340 350 360
pF1KE6 SLDSLAKHGIVALRRAKRRNMERLSLACGGMAVNSFEDLTVDCLGHAGLVYEYTLGEEKF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SLDSLAKHGIVALRRAKRRNMERLSLACGGMAVNSFEDLTVDCLGHAGLVYEYTLGEEKF
260 270 280 290 300 310
370 380 390 400 410 420
pF1KE6 TFIEECVNPCSVTLLVKGPNKHTLTQVKDAIRDGLRAIKNAIEDGCMVPGAGAIEVAMAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TFIEECVNPCSVTLLVKGPNKHTLTQVKDAIRDGLRAIKNAIEDGCMVPGAGAIEVAMAE
320 330 340 350 360 370
430 440 450 460 470 480
pF1KE6 ALVTYKNSIKGRARLGVQAFADALLIIPKVLAQNAGYDPQETLVKVQAEHVESKQLVGVD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ALVTYKNSIKGRARLGVQAFADALLIIPKVLAQNAGYDPQETLVKVQAEHVESKQLVGVD
380 390 400 410 420 430
490 500 510 520 530
pF1KE6 LNTGEPMVAADAGVWDNYCVKKQLLHSCTVIATNILLVDEIMRAGMSSLK
::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LNTGEPMVAADAGVWDNYCVKKQLLHSCTVIATNILLVDEIMRAGMSSLK
440 450 460 470 480
>>XP_011522505 (OMIM: 610730) PREDICTED: T-complex prote (388 aa)
initn: 2495 init1: 2495 opt: 2495 Z-score: 2903.9 bits: 546.5 E(85289): 5.2e-155
Smith-Waterman score: 2495; 100.0% identity (100.0% similar) in 388 aa overlap (143-530:1-388)
120 130 140 150 160 170
pF1KE6 GLHPRIIAEGFEAAKIKALEVLEEVKVTKEMKRKILLDVARTSLQTKVHAELADVLTEVV
::::::::::::::::::::::::::::::
XP_011 MKRKILLDVARTSLQTKVHAELADVLTEVV
10 20 30
180 190 200 210 220 230
pF1KE6 VDSVLAVRRPGYPIDLFMVEIMEMKHKLGTDTKLIQGLVLDHGARHPDMKKRVEDAFILI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VDSVLAVRRPGYPIDLFMVEIMEMKHKLGTDTKLIQGLVLDHGARHPDMKKRVEDAFILI
40 50 60 70 80 90
240 250 260 270 280 290
pF1KE6 CNVSLEYEKTEVNSGFFYKTAEEKEKLVKAERKFIEDRVQKIIDLKDKVCAQSNKGFVVI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CNVSLEYEKTEVNSGFFYKTAEEKEKLVKAERKFIEDRVQKIIDLKDKVCAQSNKGFVVI
100 110 120 130 140 150
300 310 320 330 340 350
pF1KE6 NQKGIDPFSLDSLAKHGIVALRRAKRRNMERLSLACGGMAVNSFEDLTVDCLGHAGLVYE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 NQKGIDPFSLDSLAKHGIVALRRAKRRNMERLSLACGGMAVNSFEDLTVDCLGHAGLVYE
160 170 180 190 200 210
360 370 380 390 400 410
pF1KE6 YTLGEEKFTFIEECVNPCSVTLLVKGPNKHTLTQVKDAIRDGLRAIKNAIEDGCMVPGAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YTLGEEKFTFIEECVNPCSVTLLVKGPNKHTLTQVKDAIRDGLRAIKNAIEDGCMVPGAG
220 230 240 250 260 270
420 430 440 450 460 470
pF1KE6 AIEVAMAEALVTYKNSIKGRARLGVQAFADALLIIPKVLAQNAGYDPQETLVKVQAEHVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AIEVAMAEALVTYKNSIKGRARLGVQAFADALLIIPKVLAQNAGYDPQETLVKVQAEHVE
280 290 300 310 320 330
480 490 500 510 520 530
pF1KE6 SKQLVGVDLNTGEPMVAADAGVWDNYCVKKQLLHSCTVIATNILLVDEIMRAGMSSLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SKQLVGVDLNTGEPMVAADAGVWDNYCVKKQLLHSCTVIATNILLVDEIMRAGMSSLK
340 350 360 370 380
>>NP_001009186 (OMIM: 104613) T-complex protein 1 subuni (486 aa)
initn: 2319 init1: 2319 opt: 2330 Z-score: 2710.6 bits: 511.1 E(85289): 3e-144
Smith-Waterman score: 2587; 77.5% identity (87.4% similar) in 530 aa overlap (1-530:1-485)
10 20 30 40 50 60
pF1KE6 MAAIKAVNSKAEVARAQAALAVNICAARGLQDVLRTNLGPKGTMKMLASGAGDIKLTKDG
:::.:..: ::::::::::::::: ::::::::::::::::::::::.::::::::::::
NP_001 MAAVKTLNPKAEVARAQAALAVNISAARGLQDVLRTNLGPKGTMKMLVSGAGDIKLTKDG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 NVLLDEMQIQHPTASLIAKVATAQDDVTGDGTTSNVLIIGELLKQADLYISEGLHPRIIA
:::: :: :::::::.
NP_001 NVLLHEM---------------------------------------------GLHPRIIT
70
130 140 150 160 170 180
pF1KE6 EGFEAAKIKALEVLEEVKVTKEMKRKILLDVARTSLQTKVHAELADVLTEVVVDSVLAVR
::::::: :::. ::::::..:: :. :.:::::::.:::::::::::::.::::.::..
NP_001 EGFEAAKEKALQFLEEVKVSREMDRETLIDVARTSLRTKVHAELADVLTEAVVDSILAIK
80 90 100 110 120 130
190 200 210 220 230 240
pF1KE6 RPGYPIDLFMVEIMEMKHKLGTDTKLIQGLVLDHGARHPDMKKRVEDAFILICNVSLEYE
. ::::::.:::::::: :::.::.::::::::::::::::::::.:: ::::::::
NP_001 KQDEPIDLFMIEIMEMKHKSETDTSLIRGLVLDHGARHPDMKKRVEDAYILTCNVSLEYE
140 150 160 170 180 190
250 260 270 280 290 300
pF1KE6 KTEVNSGFFYKTAEEKEKLVKAERKFIEDRVQKIIDLKDKVCAQSNKGFVVINQKGIDPF
:::::::::::.:::.:::::::::::::::.:::.:: :::..:.::::::::::::::
NP_001 KTEVNSGFFYKSAEEREKLVKAERKFIEDRVKKIIELKRKVCGDSDKGFVVINQKGIDPF
200 210 220 230 240 250
310 320 330 340 350 360
pF1KE6 SLDSLAKHGIVALRRAKRRNMERLSLACGGMAVNSFEDLTVDCLGHAGLVYEYTLGEEKF
:::.:.:.::::::::::::::::.:::::.:.:::.::. :::::::::::::::::::
NP_001 SLDALSKEGIVALRRAKRRNMERLTLACGGVALNSFDDLSPDCLGHAGLVYEYTLGEEKF
260 270 280 290 300 310
370 380 390 400 410 420
pF1KE6 TFIEECVNPCSVTLLVKGPNKHTLTQVKDAIRDGLRAIKNAIEDGCMVPGAGAIEVAMAE
::::.: :: :::::.::::::::::.:::.::::::.::::.:::.::::::.::::::
NP_001 TFIEKCNNPRSVTLLIKGPNKHTLTQIKDAVRDGLRAVKNAIDDGCVVPGAGAVEVAMAE
320 330 340 350 360 370
430 440 450 460 470 480
pF1KE6 ALVTYKNSIKGRARLGVQAFADALLIIPKVLAQNAGYDPQETLVKVQAEHVESKQLVGVD
::. .: :.::::.::::::::::::::::::::.:.: ::::::.:::: :: ::::::
NP_001 ALIKHKPSVKGRAQLGVQAFADALLIIPKVLAQNSGFDLQETLVKIQAEHSESGQLVGVD
380 390 400 410 420 430
490 500 510 520 530
pF1KE6 LNTGEPMVAADAGVWDNYCVKKQLLHSCTVIATNILLVDEIMRAGMSSLK
::::::::::..::::::::::::::::::::::::::::::::::::::
NP_001 LNTGEPMVAAEVGVWDNYCVKKQLLHSCTVIATNILLVDEIMRAGMSSLKG
440 450 460 470 480
>>XP_016879513 (OMIM: 610730) PREDICTED: T-complex prote (351 aa)
initn: 1860 init1: 1860 opt: 1860 Z-score: 2166.9 bits: 410.0 E(85289): 5.9e-114
Smith-Waterman score: 2166; 90.5% identity (90.5% similar) in 388 aa overlap (143-530:1-351)
120 130 140 150 160 170
pF1KE6 GLHPRIIAEGFEAAKIKALEVLEEVKVTKEMKRKILLDVARTSLQTKVHAELADVLTEVV
::::::::::::::::::::::::::::::
XP_016 MKRKILLDVARTSLQTKVHAELADVLTEVV
10 20 30
180 190 200 210 220 230
pF1KE6 VDSVLAVRRPGYPIDLFMVEIMEMKHKLGTDTKLIQGLVLDHGARHPDMKKRVEDAFILI
:::::::::::::::::::::::::::::::::
XP_016 VDSVLAVRRPGYPIDLFMVEIMEMKHKLGTDTK---------------------------
40 50 60
240 250 260 270 280 290
pF1KE6 CNVSLEYEKTEVNSGFFYKTAEEKEKLVKAERKFIEDRVQKIIDLKDKVCAQSNKGFVVI
::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ----------EVNSGFFYKTAEEKEKLVKAERKFIEDRVQKIIDLKDKVCAQSNKGFVVI
70 80 90 100 110
300 310 320 330 340 350
pF1KE6 NQKGIDPFSLDSLAKHGIVALRRAKRRNMERLSLACGGMAVNSFEDLTVDCLGHAGLVYE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 NQKGIDPFSLDSLAKHGIVALRRAKRRNMERLSLACGGMAVNSFEDLTVDCLGHAGLVYE
120 130 140 150 160 170
360 370 380 390 400 410
pF1KE6 YTLGEEKFTFIEECVNPCSVTLLVKGPNKHTLTQVKDAIRDGLRAIKNAIEDGCMVPGAG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YTLGEEKFTFIEECVNPCSVTLLVKGPNKHTLTQVKDAIRDGLRAIKNAIEDGCMVPGAG
180 190 200 210 220 230
420 430 440 450 460 470
pF1KE6 AIEVAMAEALVTYKNSIKGRARLGVQAFADALLIIPKVLAQNAGYDPQETLVKVQAEHVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AIEVAMAEALVTYKNSIKGRARLGVQAFADALLIIPKVLAQNAGYDPQETLVKVQAEHVE
240 250 260 270 280 290
480 490 500 510 520 530
pF1KE6 SKQLVGVDLNTGEPMVAADAGVWDNYCVKKQLLHSCTVIATNILLVDEIMRAGMSSLK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SKQLVGVDLNTGEPMVAADAGVWDNYCVKKQLLHSCTVIATNILLVDEIMRAGMSSLK
300 310 320 330 340 350
>>NP_001180458 (OMIM: 610730) T-complex protein 1 subuni (493 aa)
initn: 1860 init1: 1860 opt: 1860 Z-score: 2164.5 bits: 410.1 E(85289): 8e-114
Smith-Waterman score: 3021; 92.6% identity (93.0% similar) in 530 aa overlap (1-530:1-493)
10 20 30 40 50 60
pF1KE6 MAAIKAVNSKAEVARAQAALAVNICAARGLQDVLRTNLGPKGTMKMLASGAGDIKLTKDG
::::::::::::::::.::::::::::::::::::::::::::::::.::::::::::::
NP_001 MAAIKAVNSKAEVARARAALAVNICAARGLQDVLRTNLGPKGTMKMLVSGAGDIKLTKDG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 NVLLDEMQIQHPTASLIAKVATAQDDVTGDGTTSNVLIIGELLKQADLYISEGLHPRIIA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NVLLDEMQIQHPTASLIAKVATAQDDVTGDGTTSNVLIIGELLKQADLYISEGLHPRIIA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 EGFEAAKIKALEVLEEVKVTKEMKRKILLDVARTSLQTKVHAELADVLTEVVVDSVLAVR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EGFEAAKIKALEVLEEVKVTKEMKRKILLDVARTSLQTKVHAELADVLTEVVVDSVLAVR
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE6 RPGYPIDLFMVEIMEMKHKLGTDTKLIQGLVLDHGARHPDMKKRVEDAFILICNVSLEYE
:::::::::::::::::::::::::
NP_001 RPGYPIDLFMVEIMEMKHKLGTDTK-----------------------------------
190 200
250 260 270 280 290 300
pF1KE6 KTEVNSGFFYKTAEEKEKLVKAERKFIEDRVQKIIDLKDKVCAQSNKGFVVINQKGIDPF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 --EVNSGFFYKTAEEKEKLVKAERKFIEDRVQKIIDLKDKVCAQSNKGFVVINQKGIDPF
210 220 230 240 250 260
310 320 330 340 350 360
pF1KE6 SLDSLAKHGIVALRRAKRRNMERLSLACGGMAVNSFEDLTVDCLGHAGLVYEYTLGEEKF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SLDSLAKHGIVALRRAKRRNMERLSLACGGMAVNSFEDLTVDCLGHAGLVYEYTLGEEKF
270 280 290 300 310 320
370 380 390 400 410 420
pF1KE6 TFIEECVNPCSVTLLVKGPNKHTLTQVKDAIRDGLRAIKNAIEDGCMVPGAGAIEVAMAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TFIEECVNPCSVTLLVKGPNKHTLTQVKDAIRDGLRAIKNAIEDGCMVPGAGAIEVAMAE
330 340 350 360 370 380
430 440 450 460 470 480
pF1KE6 ALVTYKNSIKGRARLGVQAFADALLIIPKVLAQNAGYDPQETLVKVQAEHVESKQLVGVD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ALVTYKNSIKGRARLGVQAFADALLIIPKVLAQNAGYDPQETLVKVQAEHVESKQLVGVD
390 400 410 420 430 440
490 500 510 520 530
pF1KE6 LNTGEPMVAADAGVWDNYCVKKQLLHSCTVIATNILLVDEIMRAGMSSLK
::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LNTGEPMVAADAGVWDNYCVKKQLLHSCTVIATNILLVDEIMRAGMSSLK
450 460 470 480 490
>>NP_005989 (OMIM: 600114) T-complex protein 1 subunit g (545 aa)
initn: 781 init1: 321 opt: 890 Z-score: 1036.9 bits: 201.6 E(85289): 5.1e-51
Smith-Waterman score: 890; 29.8% identity (67.3% similar) in 523 aa overlap (8-522:13-523)
10 20 30 40 50
pF1KE6 MAAIKAVNSKAEVAR-AQAALAVNICAARGLQDVLRTNLGPKGTMKMLASGAGDI
:.: : .: .:.. :: ::. . :..:: ::::. :::: . : :
NP_005 MMGHRPVLVLSQNTKRESGRKVQSG---NINAAKTIADIIRTCLGPKSMMKMLLDPMGGI
10 20 30 40 50
60 70 80 90 100 110
pF1KE6 KLTKDGNVLLDEMQIQHPTASLIAKVATAQDDVTGDGTTSNVLIIGELLKQADLYISEGL
.:.:::..: :.:.:::.:. . ... .::. .:::::: ... ::.:. :. .. . .
NP_005 VMTNDGNAILREIQVQHPAAKSMIEISRTQDEEVGDGTTSVIILAGEMLSVAEHFLEQQM
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE6 HPRIIAEGFEAAKIKALEVLEEVKVTKEMKRK-ILLDVARTSLQTKVHAELADVLTEVVV
:: .. ... : . .:..... ... . ..:.. .:. ::. .. ... ....
NP_005 HPTVVISAYRKALDDMISTLKKISIPVDISDSDMMLNIINSSITTKAISRWSSLACNIAL
120 130 140 150 160 170
180 190 200 210 220
pF1KE6 DSVLAVR--RPGYP-IDLF-MVEIMEMKHKLGTDTKLIQGLVLDHGARHPDMKKRVEDAF
:.: :. . : ::. .... .. . :. ...:..... . :: :.. ...
NP_005 DAVKMVQFEENGRKEIDIKKYARVEKIPGGIIEDSCVLRGVMINKDVTHPRMRRYIKNPR
180 190 200 210 220 230
230 240 250 260 270 280
pF1KE6 ILICNVSLEYEKTEVNSGFFYKTAEEKEKLVKAERKFIEDRVQKIIDLKDKVCAQSNKGF
:.. . ::::.: : .. . :. .... :...:.. . ::.:: :
NP_005 IVLLDSSLEYKKGESQTDIEITREEDFTRILQMEEEYIQQLCEDIIQLKPDV--------
240 250 260 270 280
290 300 310 320 330 340
pF1KE6 VVINQKGIDPFSLDSLAKHGIVALRRAKRRNMERLSLACGGMAVNSFEDLTVDCLGH-AG
::..:::. .. : . .:.:.::... . .:.. :::. :. :.: : .: ::
NP_005 -VITEKGISDLAQHYLMRANITAIRRVRKTDNNRIARACGARIVSRPEELREDDVGTGAG
290 300 310 320 330 340
350 360 370 380 390 400
pF1KE6 LVYEYTLGEEKFTFIEECVNPCSVTLLVKGPNKHTLTQVKDAIRDGLRAIKNAIEDGCMV
:. .:.: :::: .: .: . :.:..: .:. :..:. ..:.... .:.. : .:
NP_005 LLEIKKIGDEYFTFITDCKDPKACTILLRGASKEILSEVERNLQDAMQVCRNVLLDPQLV
350 360 370 380 390 400
410 420 430 440 450 460
pF1KE6 PGAGAIEVAMAEALVTYKNSIKGRARLGVQAFADALLIIPKVLAQNAGYDPQETLVKVQA
::.:: :.:.:.::. .... : . .: :.:: .::..: :: : . . :....:
NP_005 PGGGASEMAVAHALTEKSKAMTGVEQWPYRAVAQALEVIPRTLIQNCGASTIRLLTSLRA
410 420 430 440 450 460
470 480 490 500 510 520
pF1KE6 EHV-ESKQLVGVDLNTGEPMVAADAGVWDNYCVKKQLLHSCTVIATNILLVDEIMRAGMS
.:. :. . ::. .:: . . :.:. :: : .. . :. .: .:.:.
NP_005 KHTQENCETWGVNGETGTLVDMKELGIWEPLAVKLQTYKTAVETAVLLLRIDDIVSGHKK
470 480 490 500 510 520
530
pF1KE6 SLK
NP_005 KGDDQSRQGGAPDAGQE
530 540
>>NP_036205 (OMIM: 256840,610150) T-complex protein 1 su (541 aa)
initn: 731 init1: 311 opt: 847 Z-score: 987.0 bits: 192.3 E(85289): 3.1e-48
Smith-Waterman score: 847; 32.7% identity (66.0% similar) in 523 aa overlap (19-527:33-539)
10 20 30 40
pF1KE6 MAAIKAVNSKAEVARAQAALAVNICAARGLQDVLRTNLGPKGTMKMLA
:: .: ::... ...::.:::.: ::..
NP_036 SMGTLAFDEYGRPFLIIKDQDRKSRLMGLEALKSHIMAAKAVANTMRTSLGPNGLDKMMV
10 20 30 40 50 60
50 60 70 80 90 100
pF1KE6 SGAGDIKLTKDGNVLLDEMQIQHPTASLIAKVATAQDDVTGDGTTSNVLIIGELLKQADL
. ::. .:.:: ..:. :...: :.:..... .::: :::::. :.. : ::..:.
NP_036 DKDGDVTVTNDGATILSMMDVDHQIAKLMVELSKSQDDEIGDGTTGVVVLAGALLEEAEQ
70 80 90 100 110 120
110 120 130 140 150 160
pF1KE6 YISEGLHPRIIAEGFEAAKIKALEVLEEVK--VTKEMK-RKILLDVARTSLQTKVHAELA
...:.:: ::.:.: : :.: :.... : ..: . :...:.:.: .::
NP_036 LLDRGIHPIRIADGYEQAARVAIEHLDKISDSVLVDIKDTEPLIQTAKTTLGSKVVNSCH
130 140 150 160 170 180
170 180 190 200 210
pF1KE6 DVLTEVVVDSVLAV----RRPGYPIDLFMVEIMEMKHKLG---TDTKLIQGLVLDHGARH
..:..:..::.: :: .:. :..... :.: :::::.:...:. :
NP_036 RQMAEIAVNAVLTVADMERR---DVDF---ELIKVEGKVGGRLEDTKLIKGVIVDKDFSH
190 200 210 220 230
220 230 240 250 260 270
pF1KE6 PDMKKRVEDAFILICNVSLEYEKTEVNSGFFYKTAEEKEKLVKAERKFIEDRVQKIIDLK
:.: :.:::: : : . .: : ... . ..:. . : : :.. .:. .:.:
NP_036 PQMPKKVEDAKIAILTCPFEPPKPKTKHKLDVTSVEDYKALQKYEKEKFEEMIQQI----
240 250 260 270 280 290
280 290 300 310 320 330
pF1KE6 DKVCAQSNKGFVVINQKGIDPFSLDSLAKHGIVALRRAKRRNMERLSLACGGMAVNSFED
. . . ..: : :.: . : .... :.: . ..: ...: :: : : .
NP_036 -----KETGANLAICQWGFDDEANHLLLQNNLPAVRWVGGPEIELIAIATGGRIVPRFSE
300 310 320 330 340
340 350 360 370 380 390
pF1KE6 LTVDCLGHAGLVYEYTLG--EEKFTFIEECVNPCSVTLLVKGPNKHTLTQVKDAIRDGLR
::.. :: :::: : ..: ..:. ::.: : .::....: :: . ..: ...:.:
NP_036 LTAEKLGFAGLVQEISFGTTKDKMLVIEQCKNSRAVTIFIRGGNKMIIEEAKRSLHDALC
350 360 370 380 390 400
400 410 420 430 440 450
pF1KE6 AIKNAIEDGCMVPGAGAIEVAMAEALVTYKNSIKGRARLGVQAFADALLIIPKVLAQNAG
.:.: :.:. .: :.:: :.. : :. .. . ...:::::: .:: .:..:.:
NP_036 VIRNLIRDNRVVYGGGAAEISCALAVSQEADKCPTLEQYAMRAFADALEVIPMALSENSG
410 420 430 440 450 460
460 470 480 490 500 510
pF1KE6 YDPQETLVKVQAEHV-ESKQLVGVD-LNTGEPMVAADAGVWDNYCVKKQLLHSCTVIATN
..: .:...:.:..: : . .:.: :. : . . : .. ::: . : ..
NP_036 MNPIQTMTEVRARQVKEMNPALGIDCLHKGTNDMKQQH-VIETLIGKKQQISLATQMVRM
470 480 490 500 510 520
520 530
pF1KE6 ILLVDEIMRAGMSSLK
:: .:.: . : :
NP_036 ILKIDDIRKPGESEE
530 540
530 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Nov 8 13:36:13 2016 done: Tue Nov 8 13:36:14 2016
Total Scan time: 5.990 Total Display time: 0.070
Function used was FASTA [36.3.4 Apr, 2011]