Result of FASTA (omim) for
pFN21AE6461
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE6461, 475 aa
1>>>pF1KE6461 475 - 475 aa - 475 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.5110+/-0.000368; mu= 17.0849+/- 0.023
mean_var=70.7876+/-14.774, 0's: 0 Z-trim(113.4): 36 B-trim: 97 in 1/53
Lambda= 0.152439
statistics sampled from 22699 (22733) to 22699 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.626), E-opt: 0.2 (0.267), width: 16
Scan time: 8.890
The best scores are: opt bits E(85289)
NP_149040 (OMIM: 608956) thymic stromal cotranspor ( 475) 3075 685.6 8.1e-197
NP_861450 (OMIM: 616764) solute carrier family 46 ( 461) 399 97.0 1.1e-19
XP_005266418 (OMIM: 616764) PREDICTED: solute carr ( 463) 399 97.0 1.2e-19
NP_001129391 (OMIM: 616764) solute carrier family ( 463) 399 97.0 1.2e-19
XP_016879599 (OMIM: 229050,611672) PREDICTED: prot ( 385) 284 71.7 4e-12
NP_542400 (OMIM: 229050,611672) proton-coupled fol ( 459) 284 71.7 4.7e-12
XP_005277843 (OMIM: 229050,611672) PREDICTED: prot ( 415) 170 46.7 0.00015
NP_001229295 (OMIM: 229050,611672) proton-coupled ( 431) 170 46.7 0.00016
>>NP_149040 (OMIM: 608956) thymic stromal cotransporter (475 aa)
initn: 3075 init1: 3075 opt: 3075 Z-score: 3654.5 bits: 685.6 E(85289): 8.1e-197
Smith-Waterman score: 3075; 99.8% identity (100.0% similar) in 475 aa overlap (1-475:1-475)
10 20 30 40 50 60
pF1KE6 MSPEVTCPRRGHLPRFHPRTWVEPVMASSQVAASLYDAGLLLVVKASYGTGGSSNHSASP
:::::::::::::::::::::::::.::::::::::::::::::::::::::::::::::
NP_149 MSPEVTCPRRGHLPRFHPRTWVEPVVASSQVAASLYDAGLLLVVKASYGTGGSSNHSASP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 SPRGALEDQQQRAISNFYIIYNLVVGLSPLLSAYGLGWLSDRYHRKISICMSLLGFLLSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_149 SPRGALEDQQQRAISNFYIIYNLVVGLSPLLSAYGLGWLSDRYHRKISICMSLLGFLLSR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 LGLLLKVLLDWPVEVLYGAAALNGLFGGFSAFWSGVMALGSLGSSEGRRSVRLILIDLML
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_149 LGLLLKVLLDWPVEVLYGAAALNGLFGGFSAFWSGVMALGSLGSSEGRRSVRLILIDLML
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE6 GLAGFCGSMASGHLFKQMAGHSGQGLILTACSVSCASFALLYSLLVLKVPESVAKPSQEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_149 GLAGFCGSMASGHLFKQMAGHSGQGLILTACSVSCASFALLYSLLVLKVPESVAKPSQEL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE6 PAVDTVSGTVGTYRTLDPDQLDQQYAVGHPPSPGKAKPHKTTIALLFVGAIIYDLAVVGT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_149 PAVDTVSGTVGTYRTLDPDQLDQQYAVGHPPSPGKAKPHKTTIALLFVGAIIYDLAVVGT
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE6 VDVIPLFVLREPLGWNQVQVGYGMAAGYTIFITSFLGVLVFSRCFRDTTMIMIGMVSFGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_149 VDVIPLFVLREPLGWNQVQVGYGMAAGYTIFITSFLGVLVFSRCFRDTTMIMIGMVSFGS
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE6 GALLLAFVKETYMFYIARAVMLFALIPVTTIRSAMSKLIKGSSYGKVFVILQLSLALTGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_149 GALLLAFVKETYMFYIARAVMLFALIPVTTIRSAMSKLIKGSSYGKVFVILQLSLALTGV
370 380 390 400 410 420
430 440 450 460 470
pF1KE6 VTSTLYNKIYQLTMDMFVGSCFALSSFLSFLAIIPISIVAYKQVPLSPYGDIIEK
:::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_149 VTSTLYNKIYQLTMDMFVGSCFALSSFLSFLAIIPISIVAYKQVPLSPYGDIIEK
430 440 450 460 470
>>NP_861450 (OMIM: 616764) solute carrier family 46 memb (461 aa)
initn: 433 init1: 358 opt: 399 Z-score: 474.1 bits: 97.0 E(85289): 1.1e-19
Smith-Waterman score: 577; 30.3% identity (64.2% similar) in 402 aa overlap (61-459:56-436)
40 50 60 70 80
pF1KE6 VAASLYDAGLLLVVKASYGTGGSSNHSASPSPRGALEDQQQRAISNFYIIYNLVVGLSP-
:: :.... :. .: : . .. . :: :
NP_861 QYVYRRIWEETGNYTFSSDSNISECEKNKSSPIFAFQEEVQKKVSRFNLQMD-ISGLIPG
30 40 50 60 70 80
90 100 110 120 130 140
pF1KE6 LLSAYGLGWLSDRYHRKISICMSLLGFLLSRLGLLLKVLLDWPVEVLYGAAALNGLFGGF
:.:.. : .::.: ::. . .: .: : . . : : . .: ..: ... .... :..
NP_861 LVSTFILLSISDHYGRKFPMILSSVGALATSVWLCLLCYFAFPFQLLIASTFIGAFCGNY
90 100 110 120 130 140
150 160 170 180 190 200
pF1KE6 SAFWSGVMALGSLGSSEGR-RSVRLILIDLMLGLA-GFCGSMASGHLFKQMAGHSGQGLI
..::.. .: .: . ...:. .::..:::. :. : ..::...... : . ::
NP_861 TTFWGACFAYIVDQCKEHKQKTIRIAIIDFLLGLVTGLTG-LSSGYFIREL-GFEWSFLI
150 160 170 180 190 200
210 220 230 240 250 260
pF1KE6 LTACSVSCASFALLYSLLVLKVPESVAKPSQELPAVDTVSGTVGTYRTLDPDQLDQQYAV
. .:: : :.: :. : : . . ::.. :.: . : ...: . . : .
NP_861 I---AVSLA-VNLIYILFFLGDPVKECS-SQNV----TMSCSEG-FKNL----FYRTYML
210 220 230 240
270 280 290 300 310 320
pF1KE6 GHPPSPGKAKPHKTTIALLFVGAIIYDLAVVGTVDVIPLFVLREPLGWNQVQVGYGMAAG
. : :: .. . ::. .: : ..:.: . .. :. : :: ::.: .::: : :
NP_861 FKNAS-GK---RRFLLCLLLFTVITYFFVVIGIAPIFILYELDSPLCWNEVFIGYGSALG
250 260 270 280 290 300
330 340 350 360 370 380
pF1KE6 YTIFITSFLGVLVFSRCFRDTTMIMIGMVSFGSGALLLAFVKETYMFYIARAVMLFALIP
. :.:::::. .:: :..: : .::. . .: . ::.. : :...::. .::...:
NP_861 SASFLTSFLGIWLFSYCMEDIHMAFIGIFTTMTGMAMTAFASTTLMMFLARVPFLFTIVP
310 320 330 340 350 360
390 400 410 420 430 440
pF1KE6 VTTIRSAMSKLIKGSSYGKVFVILQLSLALTGVVTSTLYNKIYQLTMDMFVGSCFALSSF
...:: .::..... : .:. . . .: ::.. . .: ::. :. . : : ::.
NP_861 FSVLRSMLSKVVRSTEQGTLFACIAFLETLGGVTAVSTFNGIYSATVAWYPGFTFLLSAG
370 380 390 400 410 420
450 460 470
pF1KE6 LSFLAIIPISIVAYKQVPLSPYGDIIEK
: .: : . .:
NP_861 LLLLPAISLCVVKCTSWNEGSYELLIQEESSEDASDR
430 440 450 460
>>XP_005266418 (OMIM: 616764) PREDICTED: solute carrier (463 aa)
initn: 433 init1: 358 opt: 399 Z-score: 474.0 bits: 97.0 E(85289): 1.2e-19
Smith-Waterman score: 577; 30.3% identity (64.2% similar) in 402 aa overlap (61-459:56-436)
40 50 60 70 80
pF1KE6 VAASLYDAGLLLVVKASYGTGGSSNHSASPSPRGALEDQQQRAISNFYIIYNLVVGLSP-
:: :.... :. .: : . .. . :: :
XP_005 QYVYRRIWEETGNYTFSSDSNISECEKNKSSPIFAFQEEVQKKVSRFNLQMD-ISGLIPG
30 40 50 60 70 80
90 100 110 120 130 140
pF1KE6 LLSAYGLGWLSDRYHRKISICMSLLGFLLSRLGLLLKVLLDWPVEVLYGAAALNGLFGGF
:.:.. : .::.: ::. . .: .: : . . : : . .: ..: ... .... :..
XP_005 LVSTFILLSISDHYGRKFPMILSSVGALATSVWLCLLCYFAFPFQLLIASTFIGAFCGNY
90 100 110 120 130 140
150 160 170 180 190 200
pF1KE6 SAFWSGVMALGSLGSSEGR-RSVRLILIDLMLGLA-GFCGSMASGHLFKQMAGHSGQGLI
..::.. .: .: . ...:. .::..:::. :. : ..::...... : . ::
XP_005 TTFWGACFAYIVDQCKEHKQKTIRIAIIDFLLGLVTGLTG-LSSGYFIREL-GFEWSFLI
150 160 170 180 190 200
210 220 230 240 250 260
pF1KE6 LTACSVSCASFALLYSLLVLKVPESVAKPSQELPAVDTVSGTVGTYRTLDPDQLDQQYAV
. .:: : :.: :. : : . . ::.. :.: . : ...: . . : .
XP_005 I---AVSLA-VNLIYILFFLGDPVKECS-SQNV----TMSCSEG-FKNL----FYRTYML
210 220 230 240
270 280 290 300 310 320
pF1KE6 GHPPSPGKAKPHKTTIALLFVGAIIYDLAVVGTVDVIPLFVLREPLGWNQVQVGYGMAAG
. : :: .. . ::. .: : ..:.: . .. :. : :: ::.: .::: : :
XP_005 FKNAS-GK---RRFLLCLLLFTVITYFFVVIGIAPIFILYELDSPLCWNEVFIGYGSALG
250 260 270 280 290 300
330 340 350 360 370 380
pF1KE6 YTIFITSFLGVLVFSRCFRDTTMIMIGMVSFGSGALLLAFVKETYMFYIARAVMLFALIP
. :.:::::. .:: :..: : .::. . .: . ::.. : :...::. .::...:
XP_005 SASFLTSFLGIWLFSYCMEDIHMAFIGIFTTMTGMAMTAFASTTLMMFLARVPFLFTIVP
310 320 330 340 350 360
390 400 410 420 430 440
pF1KE6 VTTIRSAMSKLIKGSSYGKVFVILQLSLALTGVVTSTLYNKIYQLTMDMFVGSCFALSSF
...:: .::..... : .:. . . .: ::.. . .: ::. :. . : : ::.
XP_005 FSVLRSMLSKVVRSTEQGTLFACIAFLETLGGVTAVSTFNGIYSATVAWYPGFTFLLSAG
370 380 390 400 410 420
450 460 470
pF1KE6 LSFLAIIPISIVAYKQVPLSPYGDIIEK
: .: : . .:
XP_005 LLLLPAISLCVVKCTSWNEGSYELLIQEESSEDASDRAC
430 440 450 460
>>NP_001129391 (OMIM: 616764) solute carrier family 46 m (463 aa)
initn: 433 init1: 358 opt: 399 Z-score: 474.0 bits: 97.0 E(85289): 1.2e-19
Smith-Waterman score: 577; 30.3% identity (64.2% similar) in 402 aa overlap (61-459:56-436)
40 50 60 70 80
pF1KE6 VAASLYDAGLLLVVKASYGTGGSSNHSASPSPRGALEDQQQRAISNFYIIYNLVVGLSP-
:: :.... :. .: : . .. . :: :
NP_001 QYVYRRIWEETGNYTFSSDSNISECEKNKSSPIFAFQEEVQKKVSRFNLQMD-ISGLIPG
30 40 50 60 70 80
90 100 110 120 130 140
pF1KE6 LLSAYGLGWLSDRYHRKISICMSLLGFLLSRLGLLLKVLLDWPVEVLYGAAALNGLFGGF
:.:.. : .::.: ::. . .: .: : . . : : . .: ..: ... .... :..
NP_001 LVSTFILLSISDHYGRKFPMILSSVGALATSVWLCLLCYFAFPFQLLIASTFIGAFCGNY
90 100 110 120 130 140
150 160 170 180 190 200
pF1KE6 SAFWSGVMALGSLGSSEGR-RSVRLILIDLMLGLA-GFCGSMASGHLFKQMAGHSGQGLI
..::.. .: .: . ...:. .::..:::. :. : ..::...... : . ::
NP_001 TTFWGACFAYIVDQCKEHKQKTIRIAIIDFLLGLVTGLTG-LSSGYFIREL-GFEWSFLI
150 160 170 180 190 200
210 220 230 240 250 260
pF1KE6 LTACSVSCASFALLYSLLVLKVPESVAKPSQELPAVDTVSGTVGTYRTLDPDQLDQQYAV
. .:: : :.: :. : : . . ::.. :.: . : ...: . . : .
NP_001 I---AVSLA-VNLIYILFFLGDPVKECS-SQNV----TMSCSEG-FKNL----FYRTYML
210 220 230 240
270 280 290 300 310 320
pF1KE6 GHPPSPGKAKPHKTTIALLFVGAIIYDLAVVGTVDVIPLFVLREPLGWNQVQVGYGMAAG
. : :: .. . ::. .: : ..:.: . .. :. : :: ::.: .::: : :
NP_001 FKNAS-GK---RRFLLCLLLFTVITYFFVVIGIAPIFILYELDSPLCWNEVFIGYGSALG
250 260 270 280 290 300
330 340 350 360 370 380
pF1KE6 YTIFITSFLGVLVFSRCFRDTTMIMIGMVSFGSGALLLAFVKETYMFYIARAVMLFALIP
. :.:::::. .:: :..: : .::. . .: . ::.. : :...::. .::...:
NP_001 SASFLTSFLGIWLFSYCMEDIHMAFIGIFTTMTGMAMTAFASTTLMMFLARVPFLFTIVP
310 320 330 340 350 360
390 400 410 420 430 440
pF1KE6 VTTIRSAMSKLIKGSSYGKVFVILQLSLALTGVVTSTLYNKIYQLTMDMFVGSCFALSSF
...:: .::..... : .:. . . .: ::.. . .: ::. :. . : : ::.
NP_001 FSVLRSMLSKVVRSTEQGTLFACIAFLETLGGVTAVSTFNGIYSATVAWYPGFTFLLSAG
370 380 390 400 410 420
450 460 470
pF1KE6 LSFLAIIPISIVAYKQVPLSPYGDIIEK
: .: : . .:
NP_001 LLLLPAISLCVVKCTSWNEGSYELLIQEESSEDASDRAC
430 440 450 460
>>XP_016879599 (OMIM: 229050,611672) PREDICTED: proton-c (385 aa)
initn: 329 init1: 182 opt: 284 Z-score: 338.6 bits: 71.7 E(85289): 4e-12
Smith-Waterman score: 388; 24.2% identity (57.7% similar) in 409 aa overlap (69-468:2-385)
40 50 60 70 80 90
pF1KE6 GLLLVVKASYGTGGSSNHSASPSPRGALEDQQQRAISNFYIIYNLVVG-LSPLLSAYGLG
:. ..... . .: : : : :.:. ::
XP_016 MQEVETLTSHWTLYMNVGGFLVGLFSSTLLG
10 20 30
100 110 120 130 140 150
pF1KE6 WLSDRYHRKISICMSLLGFLLSRLGLLLKVLLDWPVEVLYGAAALNGLFGGFSAFWSGVM
:: :. . .. ::.::. : .. : :. : . . : .:.: :... .. .
XP_016 AWSDSVGRRPLLVLASLGLLLQALVSVFVVQLQLHVGYFVLGRILCALLGDFGGLLAASF
40 50 60 70 80 90
160 170 180 190 200 210
pF1KE6 ALGSLGSSEGRRSVRLILIDLMLGLAGFCGSMASGHLFKQMAGHSGQGLILTACSVSCAS
: . :: :. :. :.. .:.::. .:. .:: .. . :... . : .. .
XP_016 ASVADVSSSRSRTFRMALLEASIGVAGMLASLLGGHWLRAQ-GYANPFWLALALLIAMTL
100 110 120 130 140 150
220 230 240 250 260 270
pF1KE6 FALLYSLLVLKVPESVAKPSQELPAVDTVSGTVGTYRTLDPDQLDQQYAVGHPPSPGKAK
.: . .:: :.:. . :.: .. : :.. :.: :..
XP_016 YAAFCFGETLKEPKST---------------RLFTFR--HHRSIVQLYVA---PAPEKSR
160 170 180 190
280 290 300 310 320 330
pF1KE6 PHKTTIAL-LFVGAIIYDLAVVGTVDVIPLFVLREPLGWNQVQVGYGMAAGYTIFITSFL
: . .: .:: .. :. :.. :. : :: :.. .::: :: . ..::.:
XP_016 KHLALYSLAIFVVITVH----FGAQDILTLYELSTPLCWDSKLIGYGSAAQHLPYLTSLL
200 210 220 230 240
340 350 360 370 380 390
pF1KE6 GVLVFSRCFRDTTMIMIGMVSFGSGALLLAFVKETYMFYIARAVMLFALIPVTTIRSAMS
.. ... :. :. . ::.. : ...::. : ... . ......:. . .::. .:
XP_016 ALKLLQYCLADAWVAEIGLAFNILGMVVFAFATITPLMFTGYGLLFLSLVITPVIRAKLS
250 260 270 280 290 300
400 410 420 430 440 450
pF1KE6 KLIKGSSYGKVFVILQLSLALTGVVTSTLYNKIYQLTMDMFVGSCFALSSFLSFLAIIPI
::.. . : .: . .:. ...: ..:..: :.... : : :.. : .. . :
XP_016 KLVRETEQGALFSAVACVNSLAMLTASGIFNSLYPATLNFMKGFPFLLGAGLLLIPAVLI
310 320 330 340 350 360
460 470
pF1KE6 SIVA-------YKQVPLSPYGDIIEK
... ..: : ::
XP_016 GMLEKADPHLEFQQFPQSP
370 380
>>NP_542400 (OMIM: 229050,611672) proton-coupled folate (459 aa)
initn: 379 init1: 182 opt: 284 Z-score: 337.4 bits: 71.7 E(85289): 4.7e-12
Smith-Waterman score: 412; 24.6% identity (57.7% similar) in 426 aa overlap (51-468:64-459)
30 40 50 60 70 80
pF1KE6 WVEPVMASSQVAASLYDAGLLLVVKASYGTGGSSNHSASPSPRGALEDQQQRAISNFYII
:: ::.::.:. :. ..... . .
NP_542 FALVLQGPLTTQYLWHRFSADLGYNGTRQRGGCSNRSADPTM------QEVETLTSHWTL
40 50 60 70 80
90 100 110 120 130
pF1KE6 YNLVVG-LSPLLSAYGLGWLSDRYHRKISICMSLLGFLLSRLGLLLKVLLDWPVEVLYGA
: : : : :.:. :: :: :. . .. ::.::. : .. : :. : . .
NP_542 YMNVGGFLVGLFSSTLLGAWSDSVGRRPLLVLASLGLLLQALVSVFVVQLQLHVGYFVLG
90 100 110 120 130 140
140 150 160 170 180 190
pF1KE6 AALNGLFGGFSAFWSGVMALGSLGSSEGRRSVRLILIDLMLGLAGFCGSMASGHLFKQMA
: .:.: :... .. .: . :: :. :. :.. .:.::. .:. .:: .. .
NP_542 RILCALLGDFGGLLAASFASVADVSSSRSRTFRMALLEASIGVAGMLASLLGGHWLRAQ-
150 160 170 180 190 200
200 210 220 230 240 250
pF1KE6 GHSGQGLILTACSVSCASFALLYSLLVLKVPESVAKPSQELPAVDTVSGTVGTYRTLDPD
:... . : .. . .: . .:: :.:. . :.:
NP_542 GYANPFWLALALLIAMTLYAAFCFGETLKEPKST---------------RLFTFR--HHR
210 220 230 240
260 270 280 290 300 310
pF1KE6 QLDQQYAVGHPPSPGKAKPHKTTIALLFVGAIIYDLAVVGTVDVIPLFVLREPLGWNQVQ
.. : :.. :.: :.. : .:: .. .. . :. :.. :. : :: :..
NP_542 SIVQLYVA---PAPEKSRKH---LALYSLAIFVVITVHFGAQDILTLYELSTPLCWDSKL
250 260 270 280 290 300
320 330 340 350 360 370
pF1KE6 VGYGMAAGYTIFITSFLGVLVFSRCFRDTTMIMIGMVSFGSGALLLAFVKETYMFYIARA
.::: :: . ..::.:.. ... :. :. . ::.. : ...::. : ... . .
NP_542 IGYGSAAQHLPYLTSLLALKLLQYCLADAWVAEIGLAFNILGMVVFAFATITPLMFTGYG
310 320 330 340 350 360
380 390 400 410 420 430
pF1KE6 VMLFALIPVTTIRSAMSKLIKGSSYGKVFVILQLSLALTGVVTSTLYNKIYQLTMDMFVG
.....:. . .::. .:::.. . : .: . .:. ...: ..:..: :.... :
NP_542 LLFLSLVITPVIRAKLSKLVRETEQGALFSAVACVNSLAMLTASGIFNSLYPATLNFMKG
370 380 390 400 410 420
440 450 460 470
pF1KE6 SCFALSSFLSFLAIIPISIVA-------YKQVPLSPYGDIIEK
: :.. : .. . :... ..: : ::
NP_542 FPFLLGAGLLLIPAVLIGMLEKADPHLEFQQFPQSP
430 440 450
>>XP_005277843 (OMIM: 229050,611672) PREDICTED: proton-c (415 aa)
initn: 341 init1: 144 opt: 170 Z-score: 202.6 bits: 46.7 E(85289): 0.00015
Smith-Waterman score: 298; 25.7% identity (56.3% similar) in 327 aa overlap (51-375:64-359)
30 40 50 60 70 80
pF1KE6 WVEPVMASSQVAASLYDAGLLLVVKASYGTGGSSNHSASPSPRGALEDQQQRAISNFYII
:: ::.::.:. :. ..... . .
XP_005 FALVLQGPLTTQYLWHRFSADLGYNGTRQRGGCSNRSADPTM------QEVETLTSHWTL
40 50 60 70 80
90 100 110 120 130
pF1KE6 YNLVVG-LSPLLSAYGLGWLSDRYHRKISICMSLLGFLLSRLGLLLKVLLDWPVEVLYGA
: : : : :.:. :: :: :. . .. ::.::. : .. : :. : . .
XP_005 YMNVGGFLVGLFSSTLLGAWSDSVGRRPLLVLASLGLLLQALVSVFVVQLQLHVGYFVLG
90 100 110 120 130 140
140 150 160 170 180 190
pF1KE6 AALNGLFGGFSAFWSGVMALGSLGSSEGRRSVRLILIDLMLGLAGFCGSMASGHLFKQMA
: .:.: :... .. .: . :: :. :. :.. .:.::. .:. .:: .. .
XP_005 RILCALLGDFGGLLAASFASVADVSSSRSRTFRMALLEASIGVAGMLASLLGGHWLRAQ-
150 160 170 180 190 200
200 210 220 230 240 250
pF1KE6 GHSGQGLILTACSVSCASFALLYSLLVLKVPESVAKPSQELPAVDTVSGTVGTYRTLDPD
:... . : .. . .: . .:: :.:. . :.:
XP_005 GYANPFWLALALLIAMTLYAAFCFGETLKEPKST---------------RLFTFR--HHR
210 220 230 240
260 270 280 290 300 310
pF1KE6 QLDQQYAVGHPPSPGKAKPHKTTIAL-LFVGAIIYDLAVVGTVDVIPLFVLREPLGWNQV
.. : :.. :.: :.. : . .: .:: .. :. :.. :. : :: :..
XP_005 SIVQLYVA---PAPEKSRKHLALYSLAIFVVITVH----FGAQDILTLYELSTPLCWDSK
250 260 270 280 290 300
320 330 340 350 360 370
pF1KE6 QVGYGMAAGYTIFITSFLGVLVFSRCFRDTTMIMIGMVSFGSGALLLAFVKETYMFYIAR
.::: :: . ..::.:.. ... :. :. . ::.. : ...::. : ...
XP_005 LIGYGSAAQHLPYLTSLLALKLLQYCLADAWVAEIGLAFNILGMVVFAFATITPLMFTGC
310 320 330 340 350 360
380 390 400 410 420 430
pF1KE6 AVMLFALIPVTTIRSAMSKLIKGSSYGKVFVILQLSLALTGVVTSTLYNKIYQLTMDMFV
XP_005 WKRLILTSSSSSFPRAPDLPGPEDRGQEEQSEHQATGGLQLEAQPTAGQATLV
370 380 390 400 410
>>NP_001229295 (OMIM: 229050,611672) proton-coupled fola (431 aa)
initn: 341 init1: 144 opt: 170 Z-score: 202.3 bits: 46.7 E(85289): 0.00016
Smith-Waterman score: 305; 23.7% identity (54.7% similar) in 426 aa overlap (51-468:64-431)
30 40 50 60 70 80
pF1KE6 WVEPVMASSQVAASLYDAGLLLVVKASYGTGGSSNHSASPSPRGALEDQQQRAISNFYII
:: ::.::.:. :. ..... . .
NP_001 FALVLQGPLTTQYLWHRFSADLGYNGTRQRGGCSNRSADPTM------QEVETLTSHWTL
40 50 60 70 80
90 100 110 120 130
pF1KE6 YNLVVG-LSPLLSAYGLGWLSDRYHRKISICMSLLGFLLSRLGLLLKVLLDWPVEVLYGA
: : : : :.:. :: :: :. . .. ::.::. : .. : :. : . .
NP_001 YMNVGGFLVGLFSSTLLGAWSDSVGRRPLLVLASLGLLLQALVSVFVVQLQLHVGYFVLG
90 100 110 120 130 140
140 150 160 170 180 190
pF1KE6 AALNGLFGGFSAFWSGVMALGSLGSSEGRRSVRLILIDLMLGLAGFCGSMASGHLFKQMA
: .:.: :... .. .: . :: :. :. :.. .:.::. .:. .:: .. .
NP_001 RILCALLGDFGGLLAASFASVADVSSSRSRTFRMALLEASIGVAGMLASLLGGHWLRAQ-
150 160 170 180 190 200
200 210 220 230 240 250
pF1KE6 GHSGQGLILTACSVSCASFALLYSLLVLKVPESVAKPSQELPAVDTVSGTVGTYRTLDPD
:... . : .. . .: . .:: :.:. . :.:
NP_001 GYANPFWLALALLIAMTLYAAFCFGETLKEPKST---------------RLFTFR--HHR
210 220 230 240
260 270 280 290 300 310
pF1KE6 QLDQQYAVGHPPSPGKAKPHKTTIALLFVGAIIYDLAVVGTVDVIPLFVLREPLGWNQVQ
.. : :.. :.: :.. : .:: .. .. . :. :.. :. : :: :..
NP_001 SIVQLYVA---PAPEKSRKH---LALYSLAIFVVITVHFGAQDILTLYELSTPLCWDSKL
250 260 270 280 290 300
320 330 340 350 360 370
pF1KE6 VGYGMAAGYTIFITSFLGVLVFSRCFRDTTMIMIGMVSFGSGALLLAFVKETYMFYIARA
.::: :: . ..::.:.. ... :. :. . ::. .:. .:..:
NP_001 IGYGSAAQHLPYLTSLLALKLLQYCLADAWVAEIGL-AFN----ILGMV-----------
310 320 330 340
380 390 400 410 420 430
pF1KE6 VMLFALIPVTTIRSAMSKLIKGSSYGKVFVILQLSLALTGVVTSTLYNKIYQLTMDMFVG
.::. .: . .. :. .. : . .:.. ...: ..:..: :.... :
NP_001 --VFAFATITPL------MFTGALFSAVACVNSLAM----LTASGIFNSLYPATLNFMKG
350 360 370 380 390
440 450 460 470
pF1KE6 SCFALSSFLSFLAIIPISIVA-------YKQVPLSPYGDIIEK
: :.. : .. . :... ..: : ::
NP_001 FPFLLGAGLLLIPAVLIGMLEKADPHLEFQQFPQSP
400 410 420 430
475 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Nov 8 13:31:13 2016 done: Tue Nov 8 13:31:15 2016
Total Scan time: 8.890 Total Display time: 0.040
Function used was FASTA [36.3.4 Apr, 2011]