Result of FASTA (ccds) for
pFN21AE6461
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE6461, 475 aa
1>>>pF1KE6461 475 - 475 aa - 475 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.0067+/-0.000874; mu= 14.0884+/- 0.052
mean_var=67.9625+/-14.190, 0's: 0 Z-trim(106.5): 23 B-trim: 15 in 1/50
Lambda= 0.155575
statistics sampled from 9008 (9017) to 9008 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.647), E-opt: 0.2 (0.277), width: 16
Scan time: 3.160
The best scores are: opt bits E(32554)
CCDS6786.1 SLC46A2 gene_id:57864|Hs108|chr9 ( 475) 3075 699.2 2.5e-201
CCDS9332.1 SLC46A3 gene_id:283537|Hs108|chr13 ( 461) 399 98.5 1.5e-20
CCDS45021.1 SLC46A3 gene_id:283537|Hs108|chr13 ( 463) 399 98.5 1.5e-20
CCDS74020.1 SLC46A1 gene_id:113235|Hs108|chr17 ( 459) 284 72.7 9e-13
>>CCDS6786.1 SLC46A2 gene_id:57864|Hs108|chr9 (475 aa)
initn: 3075 init1: 3075 opt: 3075 Z-score: 3728.0 bits: 699.2 E(32554): 2.5e-201
Smith-Waterman score: 3075; 99.8% identity (100.0% similar) in 475 aa overlap (1-475:1-475)
10 20 30 40 50 60
pF1KE6 MSPEVTCPRRGHLPRFHPRTWVEPVMASSQVAASLYDAGLLLVVKASYGTGGSSNHSASP
:::::::::::::::::::::::::.::::::::::::::::::::::::::::::::::
CCDS67 MSPEVTCPRRGHLPRFHPRTWVEPVVASSQVAASLYDAGLLLVVKASYGTGGSSNHSASP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 SPRGALEDQQQRAISNFYIIYNLVVGLSPLLSAYGLGWLSDRYHRKISICMSLLGFLLSR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS67 SPRGALEDQQQRAISNFYIIYNLVVGLSPLLSAYGLGWLSDRYHRKISICMSLLGFLLSR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 LGLLLKVLLDWPVEVLYGAAALNGLFGGFSAFWSGVMALGSLGSSEGRRSVRLILIDLML
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS67 LGLLLKVLLDWPVEVLYGAAALNGLFGGFSAFWSGVMALGSLGSSEGRRSVRLILIDLML
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE6 GLAGFCGSMASGHLFKQMAGHSGQGLILTACSVSCASFALLYSLLVLKVPESVAKPSQEL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS67 GLAGFCGSMASGHLFKQMAGHSGQGLILTACSVSCASFALLYSLLVLKVPESVAKPSQEL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE6 PAVDTVSGTVGTYRTLDPDQLDQQYAVGHPPSPGKAKPHKTTIALLFVGAIIYDLAVVGT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS67 PAVDTVSGTVGTYRTLDPDQLDQQYAVGHPPSPGKAKPHKTTIALLFVGAIIYDLAVVGT
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE6 VDVIPLFVLREPLGWNQVQVGYGMAAGYTIFITSFLGVLVFSRCFRDTTMIMIGMVSFGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS67 VDVIPLFVLREPLGWNQVQVGYGMAAGYTIFITSFLGVLVFSRCFRDTTMIMIGMVSFGS
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE6 GALLLAFVKETYMFYIARAVMLFALIPVTTIRSAMSKLIKGSSYGKVFVILQLSLALTGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS67 GALLLAFVKETYMFYIARAVMLFALIPVTTIRSAMSKLIKGSSYGKVFVILQLSLALTGV
370 380 390 400 410 420
430 440 450 460 470
pF1KE6 VTSTLYNKIYQLTMDMFVGSCFALSSFLSFLAIIPISIVAYKQVPLSPYGDIIEK
:::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS67 VTSTLYNKIYQLTMDMFVGSCFALSSFLSFLAIIPISIVAYKQVPLSPYGDIIEK
430 440 450 460 470
>>CCDS9332.1 SLC46A3 gene_id:283537|Hs108|chr13 (461 aa)
initn: 433 init1: 358 opt: 399 Z-score: 482.2 bits: 98.5 E(32554): 1.5e-20
Smith-Waterman score: 577; 30.3% identity (64.2% similar) in 402 aa overlap (61-459:56-436)
40 50 60 70 80
pF1KE6 VAASLYDAGLLLVVKASYGTGGSSNHSASPSPRGALEDQQQRAISNFYIIYNLVVGLSP-
:: :.... :. .: : . .. . :: :
CCDS93 QYVYRRIWEETGNYTFSSDSNISECEKNKSSPIFAFQEEVQKKVSRFNLQMD-ISGLIPG
30 40 50 60 70 80
90 100 110 120 130 140
pF1KE6 LLSAYGLGWLSDRYHRKISICMSLLGFLLSRLGLLLKVLLDWPVEVLYGAAALNGLFGGF
:.:.. : .::.: ::. . .: .: : . . : : . .: ..: ... .... :..
CCDS93 LVSTFILLSISDHYGRKFPMILSSVGALATSVWLCLLCYFAFPFQLLIASTFIGAFCGNY
90 100 110 120 130 140
150 160 170 180 190 200
pF1KE6 SAFWSGVMALGSLGSSEGR-RSVRLILIDLMLGLA-GFCGSMASGHLFKQMAGHSGQGLI
..::.. .: .: . ...:. .::..:::. :. : ..::...... : . ::
CCDS93 TTFWGACFAYIVDQCKEHKQKTIRIAIIDFLLGLVTGLTG-LSSGYFIREL-GFEWSFLI
150 160 170 180 190 200
210 220 230 240 250 260
pF1KE6 LTACSVSCASFALLYSLLVLKVPESVAKPSQELPAVDTVSGTVGTYRTLDPDQLDQQYAV
. .:: : :.: :. : : . . ::.. :.: . : ...: . . : .
CCDS93 I---AVSLA-VNLIYILFFLGDPVKECS-SQNV----TMSCSEG-FKNL----FYRTYML
210 220 230 240
270 280 290 300 310 320
pF1KE6 GHPPSPGKAKPHKTTIALLFVGAIIYDLAVVGTVDVIPLFVLREPLGWNQVQVGYGMAAG
. : :: .. . ::. .: : ..:.: . .. :. : :: ::.: .::: : :
CCDS93 FKNAS-GK---RRFLLCLLLFTVITYFFVVIGIAPIFILYELDSPLCWNEVFIGYGSALG
250 260 270 280 290 300
330 340 350 360 370 380
pF1KE6 YTIFITSFLGVLVFSRCFRDTTMIMIGMVSFGSGALLLAFVKETYMFYIARAVMLFALIP
. :.:::::. .:: :..: : .::. . .: . ::.. : :...::. .::...:
CCDS93 SASFLTSFLGIWLFSYCMEDIHMAFIGIFTTMTGMAMTAFASTTLMMFLARVPFLFTIVP
310 320 330 340 350 360
390 400 410 420 430 440
pF1KE6 VTTIRSAMSKLIKGSSYGKVFVILQLSLALTGVVTSTLYNKIYQLTMDMFVGSCFALSSF
...:: .::..... : .:. . . .: ::.. . .: ::. :. . : : ::.
CCDS93 FSVLRSMLSKVVRSTEQGTLFACIAFLETLGGVTAVSTFNGIYSATVAWYPGFTFLLSAG
370 380 390 400 410 420
450 460 470
pF1KE6 LSFLAIIPISIVAYKQVPLSPYGDIIEK
: .: : . .:
CCDS93 LLLLPAISLCVVKCTSWNEGSYELLIQEESSEDASDR
430 440 450 460
>>CCDS45021.1 SLC46A3 gene_id:283537|Hs108|chr13 (463 aa)
initn: 433 init1: 358 opt: 399 Z-score: 482.2 bits: 98.5 E(32554): 1.5e-20
Smith-Waterman score: 577; 30.3% identity (64.2% similar) in 402 aa overlap (61-459:56-436)
40 50 60 70 80
pF1KE6 VAASLYDAGLLLVVKASYGTGGSSNHSASPSPRGALEDQQQRAISNFYIIYNLVVGLSP-
:: :.... :. .: : . .. . :: :
CCDS45 QYVYRRIWEETGNYTFSSDSNISECEKNKSSPIFAFQEEVQKKVSRFNLQMD-ISGLIPG
30 40 50 60 70 80
90 100 110 120 130 140
pF1KE6 LLSAYGLGWLSDRYHRKISICMSLLGFLLSRLGLLLKVLLDWPVEVLYGAAALNGLFGGF
:.:.. : .::.: ::. . .: .: : . . : : . .: ..: ... .... :..
CCDS45 LVSTFILLSISDHYGRKFPMILSSVGALATSVWLCLLCYFAFPFQLLIASTFIGAFCGNY
90 100 110 120 130 140
150 160 170 180 190 200
pF1KE6 SAFWSGVMALGSLGSSEGR-RSVRLILIDLMLGLA-GFCGSMASGHLFKQMAGHSGQGLI
..::.. .: .: . ...:. .::..:::. :. : ..::...... : . ::
CCDS45 TTFWGACFAYIVDQCKEHKQKTIRIAIIDFLLGLVTGLTG-LSSGYFIREL-GFEWSFLI
150 160 170 180 190 200
210 220 230 240 250 260
pF1KE6 LTACSVSCASFALLYSLLVLKVPESVAKPSQELPAVDTVSGTVGTYRTLDPDQLDQQYAV
. .:: : :.: :. : : . . ::.. :.: . : ...: . . : .
CCDS45 I---AVSLA-VNLIYILFFLGDPVKECS-SQNV----TMSCSEG-FKNL----FYRTYML
210 220 230 240
270 280 290 300 310 320
pF1KE6 GHPPSPGKAKPHKTTIALLFVGAIIYDLAVVGTVDVIPLFVLREPLGWNQVQVGYGMAAG
. : :: .. . ::. .: : ..:.: . .. :. : :: ::.: .::: : :
CCDS45 FKNAS-GK---RRFLLCLLLFTVITYFFVVIGIAPIFILYELDSPLCWNEVFIGYGSALG
250 260 270 280 290 300
330 340 350 360 370 380
pF1KE6 YTIFITSFLGVLVFSRCFRDTTMIMIGMVSFGSGALLLAFVKETYMFYIARAVMLFALIP
. :.:::::. .:: :..: : .::. . .: . ::.. : :...::. .::...:
CCDS45 SASFLTSFLGIWLFSYCMEDIHMAFIGIFTTMTGMAMTAFASTTLMMFLARVPFLFTIVP
310 320 330 340 350 360
390 400 410 420 430 440
pF1KE6 VTTIRSAMSKLIKGSSYGKVFVILQLSLALTGVVTSTLYNKIYQLTMDMFVGSCFALSSF
...:: .::..... : .:. . . .: ::.. . .: ::. :. . : : ::.
CCDS45 FSVLRSMLSKVVRSTEQGTLFACIAFLETLGGVTAVSTFNGIYSATVAWYPGFTFLLSAG
370 380 390 400 410 420
450 460 470
pF1KE6 LSFLAIIPISIVAYKQVPLSPYGDIIEK
: .: : . .:
CCDS45 LLLLPAISLCVVKCTSWNEGSYELLIQEESSEDASDRAC
430 440 450 460
>>CCDS74020.1 SLC46A1 gene_id:113235|Hs108|chr17 (459 aa)
initn: 379 init1: 182 opt: 284 Z-score: 342.8 bits: 72.7 E(32554): 9e-13
Smith-Waterman score: 412; 24.6% identity (57.7% similar) in 426 aa overlap (51-468:64-459)
30 40 50 60 70 80
pF1KE6 WVEPVMASSQVAASLYDAGLLLVVKASYGTGGSSNHSASPSPRGALEDQQQRAISNFYII
:: ::.::.:. :. ..... . .
CCDS74 FALVLQGPLTTQYLWHRFSADLGYNGTRQRGGCSNRSADPTM------QEVETLTSHWTL
40 50 60 70 80
90 100 110 120 130
pF1KE6 YNLVVG-LSPLLSAYGLGWLSDRYHRKISICMSLLGFLLSRLGLLLKVLLDWPVEVLYGA
: : : : :.:. :: :: :. . .. ::.::. : .. : :. : . .
CCDS74 YMNVGGFLVGLFSSTLLGAWSDSVGRRPLLVLASLGLLLQALVSVFVVQLQLHVGYFVLG
90 100 110 120 130 140
140 150 160 170 180 190
pF1KE6 AALNGLFGGFSAFWSGVMALGSLGSSEGRRSVRLILIDLMLGLAGFCGSMASGHLFKQMA
: .:.: :... .. .: . :: :. :. :.. .:.::. .:. .:: .. .
CCDS74 RILCALLGDFGGLLAASFASVADVSSSRSRTFRMALLEASIGVAGMLASLLGGHWLRAQ-
150 160 170 180 190 200
200 210 220 230 240 250
pF1KE6 GHSGQGLILTACSVSCASFALLYSLLVLKVPESVAKPSQELPAVDTVSGTVGTYRTLDPD
:... . : .. . .: . .:: :.:. . :.:
CCDS74 GYANPFWLALALLIAMTLYAAFCFGETLKEPKST---------------RLFTFR--HHR
210 220 230 240
260 270 280 290 300 310
pF1KE6 QLDQQYAVGHPPSPGKAKPHKTTIALLFVGAIIYDLAVVGTVDVIPLFVLREPLGWNQVQ
.. : :.. :.: :.. : .:: .. .. . :. :.. :. : :: :..
CCDS74 SIVQLYVA---PAPEKSRKH---LALYSLAIFVVITVHFGAQDILTLYELSTPLCWDSKL
250 260 270 280 290 300
320 330 340 350 360 370
pF1KE6 VGYGMAAGYTIFITSFLGVLVFSRCFRDTTMIMIGMVSFGSGALLLAFVKETYMFYIARA
.::: :: . ..::.:.. ... :. :. . ::.. : ...::. : ... . .
CCDS74 IGYGSAAQHLPYLTSLLALKLLQYCLADAWVAEIGLAFNILGMVVFAFATITPLMFTGYG
310 320 330 340 350 360
380 390 400 410 420 430
pF1KE6 VMLFALIPVTTIRSAMSKLIKGSSYGKVFVILQLSLALTGVVTSTLYNKIYQLTMDMFVG
.....:. . .::. .:::.. . : .: . .:. ...: ..:..: :.... :
CCDS74 LLFLSLVITPVIRAKLSKLVRETEQGALFSAVACVNSLAMLTASGIFNSLYPATLNFMKG
370 380 390 400 410 420
440 450 460 470
pF1KE6 SCFALSSFLSFLAIIPISIVA-------YKQVPLSPYGDIIEK
: :.. : .. . :... ..: : ::
CCDS74 FPFLLGAGLLLIPAVLIGMLEKADPHLEFQQFPQSP
430 440 450
475 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Nov 8 13:31:13 2016 done: Tue Nov 8 13:31:13 2016
Total Scan time: 3.160 Total Display time: 0.010
Function used was FASTA [36.3.4 Apr, 2011]