Result of FASTA (omim) for
pFN21AE6449
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE6449, 534 aa
1>>>pF1KE6449 534 - 534 aa - 534 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.3418+/-0.000507; mu= 18.0705+/- 0.031
mean_var=75.2546+/-14.856, 0's: 0 Z-trim(108.5): 71 B-trim: 203 in 1/49
Lambda= 0.147845
statistics sampled from 16559 (16630) to 16559 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.54), E-opt: 0.2 (0.195), width: 16
Scan time: 6.780
The best scores are: opt bits E(85289)
NP_061951 (OMIM: 606430) UDP-glucuronosyltransfera ( 534) 3577 773.3 0
NP_061966 (OMIM: 606428) UDP-glucuronosyltransfera ( 534) 3404 736.4 5.2e-212
NP_009051 (OMIM: 606429) UDP-glucuronosyltransfera ( 534) 3357 726.3 5.5e-209
NP_000454 (OMIM: 143500,191740,218800,237900,60181 ( 533) 2635 572.3 1.2e-162
NP_066307 (OMIM: 606434) UDP-glucuronosyltransfera ( 530) 2422 526.9 5.9e-149
NP_061949 (OMIM: 606433) UDP-glucuronosyltransfera ( 530) 2416 525.6 1.4e-148
NP_061948 (OMIM: 606435) UDP-glucuronosyltransfera ( 530) 2369 515.6 1.5e-145
NP_001063 (OMIM: 606431) UDP-glucuronosyltransfera ( 532) 2368 515.4 1.7e-145
NP_061950 (OMIM: 606432) UDP-glucuronosyltransfera ( 530) 2363 514.3 3.6e-145
NP_995584 (OMIM: 606431) UDP-glucuronosyltransfera ( 265) 1751 383.6 4.1e-106
NP_001068 (OMIM: 601903,612560) UDP-glucuronosyltr ( 530) 1512 332.8 1.6e-90
NP_001066 (OMIM: 600070) UDP-glucuronosyltransfera ( 528) 1497 329.6 1.4e-89
NP_066962 (OMIM: 600067) UDP-glucuronosyltransfera ( 528) 1496 329.4 1.7e-89
XP_016864074 (OMIM: 600070) PREDICTED: UDP-glucuro ( 525) 1480 326.0 1.8e-88
NP_001067 (OMIM: 600069) UDP-glucuronosyltransfera ( 530) 1474 324.7 4.4e-88
NP_001065 (OMIM: 600068) UDP-glucuronosyltransfera ( 529) 1469 323.6 9.1e-88
NP_006789 (OMIM: 604716) UDP-glucuronosyltransfera ( 527) 1463 322.4 2.2e-87
NP_001064 (OMIM: 603064) UDP-glucuronosyltransfera ( 529) 1461 321.9 3e-87
NP_444267 (OMIM: 606497) UDP-glucuronosyltransfera ( 529) 1460 321.7 3.4e-87
NP_079019 (OMIM: 616382) UDP-glucuronosyltransfera ( 527) 1406 310.2 1e-83
XP_011530549 (OMIM: 616382) PREDICTED: UDP-glucuro ( 533) 1296 286.7 1.2e-76
NP_001284545 (OMIM: 600067) UDP-glucuronosyltransf ( 392) 1293 286.0 1.4e-76
NP_001138239 (OMIM: 600070) UDP-glucuronosyltransf ( 444) 1161 257.9 4.7e-68
NP_001277020 (OMIM: 600070) UDP-glucuronosyltransf ( 280) 1153 256.0 1.1e-67
XP_005265759 (OMIM: 600068) PREDICTED: UDP-glucuro ( 280) 1149 255.2 1.9e-67
XP_011529852 (OMIM: 603064) PREDICTED: UDP-glucuro ( 445) 1127 250.6 7.2e-66
XP_016863150 (OMIM: 603064) PREDICTED: UDP-glucuro ( 280) 1118 248.6 1.9e-65
XP_016863149 (OMIM: 603064) PREDICTED: UDP-glucuro ( 280) 1118 248.6 1.9e-65
NP_001239204 (OMIM: 604716) UDP-glucuronosyltransf ( 527) 1094 243.6 1.1e-63
XP_011530531 (OMIM: 600068) PREDICTED: UDP-glucuro ( 450) 1051 234.4 5.5e-61
NP_001309041 (OMIM: 601291) 2-hydroxyacylsphingosi ( 541) 1012 226.2 2e-58
NP_003351 (OMIM: 601291) 2-hydroxyacylsphingosine ( 541) 1012 226.2 2e-58
NP_001309042 (OMIM: 601291) 2-hydroxyacylsphingosi ( 541) 1012 226.2 2e-58
NP_001121646 (OMIM: 601291) 2-hydroxyacylsphingosi ( 541) 1012 226.2 2e-58
NP_001309043 (OMIM: 601291) 2-hydroxyacylsphingosi ( 541) 1012 226.2 2e-58
XP_016863792 (OMIM: 606497) PREDICTED: UDP-glucuro ( 391) 926 207.7 5.3e-53
NP_777574 (OMIM: 616384) UDP-glucuronosyltransfera ( 523) 876 197.1 1.1e-49
NP_689617 (OMIM: 616383) UDP-glucuronosyltransfera ( 523) 859 193.5 1.3e-48
NP_001288168 (OMIM: 604716) UDP-glucuronosyltransf ( 483) 858 193.3 1.4e-48
NP_001239203 (OMIM: 604716) UDP-glucuronosyltransf ( 693) 858 193.4 1.9e-48
XP_016864639 (OMIM: 616384) PREDICTED: UDP-glucuro ( 485) 832 187.7 6.8e-47
NP_001161788 (OMIM: 616384) UDP-glucuronosyltransf ( 489) 825 186.2 1.9e-46
XP_011512290 (OMIM: 616384) PREDICTED: UDP-glucuro ( 550) 817 184.6 6.9e-46
XP_011512259 (OMIM: 616383) PREDICTED: UDP-glucuro ( 492) 815 184.1 8.4e-46
XP_011512260 (OMIM: 616383) PREDICTED: UDP-glucuro ( 489) 807 182.4 2.7e-45
XP_005248300 (OMIM: 616383) PREDICTED: UDP-glucuro ( 469) 804 181.8 4.1e-45
XP_011512261 (OMIM: 616383) PREDICTED: UDP-glucuro ( 469) 804 181.8 4.1e-45
NP_001284544 (OMIM: 600067) UDP-glucuronosyltransf ( 369) 787 178.1 4.2e-44
XP_011512263 (OMIM: 616383) PREDICTED: UDP-glucuro ( 410) 787 178.1 4.6e-44
NP_001317648 (OMIM: 600068) UDP-glucuronosyltransf ( 369) 761 172.5 2e-42
>>NP_061951 (OMIM: 606430) UDP-glucuronosyltransferase 1 (534 aa)
initn: 3577 init1: 3577 opt: 3577 Z-score: 4126.6 bits: 773.3 E(85289): 0
Smith-Waterman score: 3577; 100.0% identity (100.0% similar) in 534 aa overlap (1-534:1-534)
10 20 30 40 50 60
pF1KE6 MATGLQVPLPQLATGLLLLLSVQPWAESGKVLVVPTDGSHWLSMREALRDLHARGHQVVV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 MATGLQVPLPQLATGLLLLLSVQPWAESGKVLVVPTDGSHWLSMREALRDLHARGHQVVV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 LTLEVNMYIKEENFFTLTTYAISWTQDEFDRLLLGHTQSFFETEHLLMKFSRRMAIMNNM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 LTLEVNMYIKEENFFTLTTYAISWTQDEFDRLLLGHTQSFFETEHLLMKFSRRMAIMNNM
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 SLIIHRSCVELLHNEALIRHLHATSFDVVLTDPFHLCAAVLAKYLSIPAVFFLRNIPCDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 SLIIHRSCVELLHNEALIRHLHATSFDVVLTDPFHLCAAVLAKYLSIPAVFFLRNIPCDL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE6 DFKGTQCPNPSSYIPRLLTTNSDHMTFLQRVKNMLYPLALSYLCHAVSAPYASLASELFQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 DFKGTQCPNPSSYIPRLLTTNSDHMTFLQRVKNMLYPLALSYLCHAVSAPYASLASELFQ
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE6 REVSVVDLVSHASVWLFRGDFVMDYPRPIMPNMVFIGGINCANGKPLSQEFEAYINASGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 REVSVVDLVSHASVWLFRGDFVMDYPRPIMPNMVFIGGINCANGKPLSQEFEAYINASGE
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE6 HGIVVFSLGSMVSEIPEKKAMAIADALGKIPQTVLWRYTGTRPSNLANNTILVKWLPQND
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 HGIVVFSLGSMVSEIPEKKAMAIADALGKIPQTVLWRYTGTRPSNLANNTILVKWLPQND
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE6 LLGHPMTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMDNAKRMETKGAGVTLNVLEMT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 LLGHPMTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMDNAKRMETKGAGVTLNVLEMT
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE6 SEDLENALKAVINDKSYKENIMRLSSLHKDRPVEPLDLAVFWVEFVMRHKGAPHLRPAAH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 SEDLENALKAVINDKSYKENIMRLSSLHKDRPVEPLDLAVFWVEFVMRHKGAPHLRPAAH
430 440 450 460 470 480
490 500 510 520 530
pF1KE6 DLTWYQYHSLDVIGFLLAVVLTVAFITFKCCAYGYRKCLGKKGRVKKAHKSKTH
::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 DLTWYQYHSLDVIGFLLAVVLTVAFITFKCCAYGYRKCLGKKGRVKKAHKSKTH
490 500 510 520 530
>>NP_061966 (OMIM: 606428) UDP-glucuronosyltransferase 1 (534 aa)
initn: 3404 init1: 3404 opt: 3404 Z-score: 3927.2 bits: 736.4 E(85289): 5.2e-212
Smith-Waterman score: 3404; 94.6% identity (97.8% similar) in 534 aa overlap (1-534:1-534)
10 20 30 40 50 60
pF1KE6 MATGLQVPLPQLATGLLLLLSVQPWAESGKVLVVPTDGSHWLSMREALRDLHARGHQVVV
:::::::::: :::::::::::::::::::::::: ::::::::::.::.:::::::.::
NP_061 MATGLQVPLPWLATGLLLLLSVQPWAESGKVLVVPIDGSHWLSMREVLRELHARGHQAVV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 LTLEVNMYIKEENFFTLTTYAISWTQDEFDRLLLGHTQSFFETEHLLMKFSRRMAIMNNM
:: ::::.::::::::::::::::::::::: .::::: .:::::.: :: : ::..:::
NP_061 LTPEVNMHIKEENFFTLTTYAISWTQDEFDRHVLGHTQLYFETEHFLKKFFRSMAMLNNM
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 SLIIHRSCVELLHNEALIRHLHATSFDVVLTDPFHLCAAVLAKYLSIPAVFFLRNIPCDL
::. :::::::::::::::::.::::::::::: .:::::::::::::.:::::::::::
NP_061 SLVYHRSCVELLHNEALIRHLNATSFDVVLTDPVNLCAAVLAKYLSIPTVFFLRNIPCDL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE6 DFKGTQCPNPSSYIPRLLTTNSDHMTFLQRVKNMLYPLALSYLCHAVSAPYASLASELFQ
:::::::::::::::::::::::::::.::::::::::::::.::: :::::::::::::
NP_061 DFKGTQCPNPSSYIPRLLTTNSDHMTFMQRVKNMLYPLALSYICHAFSAPYASLASELFQ
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE6 REVSVVDLVSHASVWLFRGDFVMDYPRPIMPNMVFIGGINCANGKPLSQEFEAYINASGE
:::::::..:::::::::::::::::::::::::::::::::: ::::::::::::::::
NP_061 REVSVVDILSHASVWLFRGDFVMDYPRPIMPNMVFIGGINCANRKPLSQEFEAYINASGE
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE6 HGIVVFSLGSMVSEIPEKKAMAIADALGKIPQTVLWRYTGTRPSNLANNTILVKWLPQND
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 HGIVVFSLGSMVSEIPEKKAMAIADALGKIPQTVLWRYTGTRPSNLANNTILVKWLPQND
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE6 LLGHPMTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMDNAKRMETKGAGVTLNVLEMT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 LLGHPMTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMDNAKRMETKGAGVTLNVLEMT
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE6 SEDLENALKAVINDKSYKENIMRLSSLHKDRPVEPLDLAVFWVEFVMRHKGAPHLRPAAH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 SEDLENALKAVINDKSYKENIMRLSSLHKDRPVEPLDLAVFWVEFVMRHKGAPHLRPAAH
430 440 450 460 470 480
490 500 510 520 530
pF1KE6 DLTWYQYHSLDVIGFLLAVVLTVAFITFKCCAYGYRKCLGKKGRVKKAHKSKTH
::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 DLTWYQYHSLDVIGFLLAVVLTVAFITFKCCAYGYRKCLGKKGRVKKAHKSKTH
490 500 510 520 530
>>NP_009051 (OMIM: 606429) UDP-glucuronosyltransferase 1 (534 aa)
initn: 3357 init1: 3357 opt: 3357 Z-score: 3873.0 bits: 726.3 E(85289): 5.5e-209
Smith-Waterman score: 3357; 93.4% identity (97.4% similar) in 534 aa overlap (1-534:1-534)
10 20 30 40 50 60
pF1KE6 MATGLQVPLPQLATGLLLLLSVQPWAESGKVLVVPTDGSHWLSMREALRDLHARGHQVVV
:: :::::::.:::::::::::::::::::::::::::: :::::::::.:::::::.::
NP_009 MARGLQVPLPRLATGLLLLLSVQPWAESGKVLVVPTDGSPWLSMREALRELHARGHQAVV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 LTLEVNMYIKEENFFTLTTYAISWTQDEFDRLLLGHTQSFFETEHLLMKFSRRMAIMNNM
:: ::::.::::.:::::.::. ::: ::::. ::.::.:::::::: ..:: ::::::.
NP_009 LTPEVNMHIKEEKFFTLTAYAVPWTQKEFDRVTLGYTQGFFETEHLLKRYSRSMAIMNNV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 SLIIHRSCVELLHNEALIRHLHATSFDVVLTDPFHLCAAVLAKYLSIPAVFFLRNIPCDL
:: .:: ::::::::::::::.::::::::::: .::.:::::::::::::: : :::::
NP_009 SLALHRCCVELLHNEALIRHLNATSFDVVLTDPVNLCGAVLAKYLSIPAVFFWRYIPCDL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE6 DFKGTQCPNPSSYIPRLLTTNSDHMTFLQRVKNMLYPLALSYLCHAVSAPYASLASELFQ
:::::::::::::::.::::::::::::::::::::::::::.::. :::::::::::::
NP_009 DFKGTQCPNPSSYIPKLLTTNSDHMTFLQRVKNMLYPLALSYICHTFSAPYASLASELFQ
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE6 REVSVVDLVSHASVWLFRGDFVMDYPRPIMPNMVFIGGINCANGKPLSQEFEAYINASGE
::::::::::.:::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 REVSVVDLVSYASVWLFRGDFVMDYPRPIMPNMVFIGGINCANGKPLSQEFEAYINASGE
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE6 HGIVVFSLGSMVSEIPEKKAMAIADALGKIPQTVLWRYTGTRPSNLANNTILVKWLPQND
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 HGIVVFSLGSMVSEIPEKKAMAIADALGKIPQTVLWRYTGTRPSNLANNTILVKWLPQND
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE6 LLGHPMTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMDNAKRMETKGAGVTLNVLEMT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 LLGHPMTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMDNAKRMETKGAGVTLNVLEMT
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE6 SEDLENALKAVINDKSYKENIMRLSSLHKDRPVEPLDLAVFWVEFVMRHKGAPHLRPAAH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 SEDLENALKAVINDKSYKENIMRLSSLHKDRPVEPLDLAVFWVEFVMRHKGAPHLRPAAH
430 440 450 460 470 480
490 500 510 520 530
pF1KE6 DLTWYQYHSLDVIGFLLAVVLTVAFITFKCCAYGYRKCLGKKGRVKKAHKSKTH
::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 DLTWYQYHSLDVIGFLLAVVLTVAFITFKCCAYGYRKCLGKKGRVKKAHKSKTH
490 500 510 520 530
>>NP_000454 (OMIM: 143500,191740,218800,237900,601816,60 (533 aa)
initn: 2633 init1: 2633 opt: 2635 Z-score: 3040.7 bits: 572.3 E(85289): 1.2e-162
Smith-Waterman score: 2635; 72.8% identity (88.6% similar) in 534 aa overlap (1-534:1-533)
10 20 30 40 50 60
pF1KE6 MATGLQVPLPQLATGLLLLLSVQPWAESGKVLVVPTDGSHWLSMREALRDLHARGHQVVV
::. : : :. :::: . ...::.:..:.:::::::: :...:. :::..::
NP_000 MAVESQGGRP-LVLGLLLCVLGPVVSHAGKILLIPVDGSHWLSMLGAIQQLQQRGHEIVV
10 20 30 40 50
70 80 90 100 110 120
pF1KE6 LTLEVNMYIKEENFFTLTTYAISWTQDEFDRLLLGHTQSFFETEHLLMKFSRRMAIMNNM
:. ....::.. :.:: :: . . ... . ... .. ::.. .:.. . . ...
NP_000 LAPDASLYIRDGAFYTLKTYPVPFQREDVKESFVSLGHNVFENDSFLQRVIKTYKKIKKD
60 70 80 90 100 110
130 140 150 160 170 180
pF1KE6 SLIIHRSCVELLHNEALIRHLHATSFDVVLTDPFHLCAAVLAKYLSIPAVFFLRNIPCDL
: .. .: .::::. :. : .::::.::::: :. ..:.:::.:.::::. .::.:
NP_000 SAMLLSGCSHLLHNKELMASLAESSFDVMLTDPFLPCSPIVAQYLSLPTVFFLHALPCSL
120 130 140 150 160 170
190 200 210 220 230 240
pF1KE6 DFKGTQCPNPSSYIPRLLTTNSDHMTFLQRVKNMLYPLALSYLCHAVSAPYASLASELFQ
.:..:::::: ::.:: :...:::::::::::::: .. ..:: .: .:::.::::..:
NP_000 EFEATQCPNPFSYVPRPLSSHSDHMTFLQRVKNMLIAFSQNFLCDVVYSPYATLASEFLQ
180 190 200 210 220 230
250 260 270 280 290 300
pF1KE6 REVSVVDLVSHASVWLFRGDFVMDYPRPIMPNMVFIGGINCANGKPLSQEFEAYINASGE
:::.: ::.: :::::::.::: ::::::::::::.::::: . .:::::::::::::::
NP_000 REVTVQDLLSSASVWLFRSDFVKDYPRPIMPNMVFVGGINCLHQNPLSQEFEAYINASGE
240 250 260 270 280 290
310 320 330 340 350 360
pF1KE6 HGIVVFSLGSMVSEIPEKKAMAIADALGKIPQTVLWRYTGTRPSNLANNTILVKWLPQND
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 HGIVVFSLGSMVSEIPEKKAMAIADALGKIPQTVLWRYTGTRPSNLANNTILVKWLPQND
300 310 320 330 340 350
370 380 390 400 410 420
pF1KE6 LLGHPMTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMDNAKRMETKGAGVTLNVLEMT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 LLGHPMTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMDNAKRMETKGAGVTLNVLEMT
360 370 380 390 400 410
430 440 450 460 470 480
pF1KE6 SEDLENALKAVINDKSYKENIMRLSSLHKDRPVEPLDLAVFWVEFVMRHKGAPHLRPAAH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 SEDLENALKAVINDKSYKENIMRLSSLHKDRPVEPLDLAVFWVEFVMRHKGAPHLRPAAH
420 430 440 450 460 470
490 500 510 520 530
pF1KE6 DLTWYQYHSLDVIGFLLAVVLTVAFITFKCCAYGYRKCLGKKGRVKKAHKSKTH
::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 DLTWYQYHSLDVIGFLLAVVLTVAFITFKCCAYGYRKCLGKKGRVKKAHKSKTH
480 490 500 510 520 530
>>NP_066307 (OMIM: 606434) UDP-glucuronosyltransferase 1 (530 aa)
initn: 2403 init1: 2217 opt: 2422 Z-score: 2795.2 bits: 526.9 E(85289): 5.9e-149
Smith-Waterman score: 2422; 69.1% identity (83.3% similar) in 534 aa overlap (3-534:4-530)
10 20 30 40 50
pF1KE6 MATGLQVPLPQLATGLLLLLSVQPWAESGKVLVVPTDGSHWLSMREALRDLHARGHQVV
:: ::: : . ::: . .::.::.:::: :::::..:: ... : :::.::
NP_066 MACTGWTSPLP-LCVCLLLTCG---FAEAGKLLVVPMDGSHWFTMRSVVEKLILRGHEVV
10 20 30 40 50
60 70 80 90 100 110
pF1KE6 VLTLEVNMYIKEENFFTLTTYAISWTQDEFDRLL--LGHTQSFFETEHLLMKFSRRMAIM
:. ::. . . :. ::. :.: ...:: . ..:.: ... . .: :. .
NP_066 VVMPEVSWQLGRSLNCTVKTYSTSYTLEDLDREFKAFAHAQWKAQVRSI---YSLLMGSY
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE6 NNMSLIIHRSCVELLHNEALIRHLHATSFDVVLTDPFHLCAAVLAKYLSIPAVFFLRNIP
:.. .. .: :.... :...:. .:::.:. ::: :. ..:::.:.:.: : :.:
NP_066 NDIFDLFFSNCRSLFKDKKLVEYLKESSFDAVFLDPFDNCGLIVAKYFSLPSVVFARGIL
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE6 CDLDFKGTQCPNPSSYIPRLLTTNSDHMTFLQRVKNMLYPLALSYLCHAVSAPYASLASE
: .:.::: : ::.::.: :: ::: .::.: .. : ::: .:::
NP_066 CHYLEEGAQCPAPLSYVPRILLGFSDAMTFKERVRNHIMHLEEHLLCHRFFKNALEIASE
180 190 200 210 220 230
240 250 260 270 280 290
pF1KE6 LFQREVSVVDLVSHASVWLFRGDFVMDYPRPIMPNMVFIGGINCANGKPLSQEFEAYINA
..: :. :: ::.:.::.: :::.:::.:.::::.::::::: .:::: .::::::::
NP_066 ILQTPVTEYDLYSHTSIWLLRTDFVLDYPKPVMPNMIFIGGINCHQGKPLPMEFEAYINA
240 250 260 270 280 290
300 310 320 330 340 350
pF1KE6 SGEHGIVVFSLGSMVSEIPEKKAMAIADALGKIPQTVLWRYTGTRPSNLANNTILVKWLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_066 SGEHGIVVFSLGSMVSEIPEKKAMAIADALGKIPQTVLWRYTGTRPSNLANNTILVKWLP
300 310 320 330 340 350
360 370 380 390 400 410
pF1KE6 QNDLLGHPMTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMDNAKRMETKGAGVTLNVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_066 QNDLLGHPMTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMDNAKRMETKGAGVTLNVL
360 370 380 390 400 410
420 430 440 450 460 470
pF1KE6 EMTSEDLENALKAVINDKSYKENIMRLSSLHKDRPVEPLDLAVFWVEFVMRHKGAPHLRP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_066 EMTSEDLENALKAVINDKSYKENIMRLSSLHKDRPVEPLDLAVFWVEFVMRHKGAPHLRP
420 430 440 450 460 470
480 490 500 510 520 530
pF1KE6 AAHDLTWYQYHSLDVIGFLLAVVLTVAFITFKCCAYGYRKCLGKKGRVKKAHKSKTH
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_066 AAHDLTWYQYHSLDVIGFLLAVVLTVAFITFKCCAYGYRKCLGKKGRVKKAHKSKTH
480 490 500 510 520 530
>>NP_061949 (OMIM: 606433) UDP-glucuronosyltransferase 1 (530 aa)
initn: 2401 init1: 2219 opt: 2416 Z-score: 2788.3 bits: 525.6 E(85289): 1.4e-148
Smith-Waterman score: 2416; 68.4% identity (83.8% similar) in 532 aa overlap (3-534:4-530)
10 20 30 40 50
pF1KE6 MATGLQVPLPQLATGLLLLLSVQPWAESGKVLVVPTDGSHWLSMREALRDLHARGHQVV
:: :.: : ..::: . .::.::.:::: :::::..:. ... : :::.::
NP_061 MARTGWTSPIP-LCVSLLLTCG---FAEAGKLLVVPMDGSHWFTMQSVVEKLILRGHEVV
10 20 30 40 50
60 70 80 90 100 110
pF1KE6 VLTLEVNMYIKEENFFTLTTYAISWTQDEFDRLLLGHTQSFFETEHLLMKFSRRMAIMNN
:. ::. . . :. ::. :.: ...:: .. ... .... . :: .. :.
NP_061 VVMPEVSWQLGKSLNCTVKTYSTSYTLEDLDREFMDFADAQWKAQ-VRSLFSLFLSSSNG
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE6 MSLIIHRSCVELLHNEALIRHLHATSFDVVLTDPFHLCAAVLAKYLSIPAVFFLRNIPCD
. .. : :.... :...:. .:::.:. ::: :. ..:::.:.:.: : :.: :
NP_061 FFNLFFSHCRSLFNDRKLVEYLKESSFDAVFLDPFDACGLIVAKYFSLPSVVFARGIACH
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE6 LDFKGTQCPNPSSYIPRLLTTNSDHMTFLQRVKNMLYPLALSYLCHAVSAPYASLASELF
.:.::: : ::.::.: :: ::: .::.: .. : .:. : .:::..
NP_061 YLEEGAQCPAPLSYVPRILLGFSDAMTFKERVRNHIMHLEEHLFCQYFSKNALEIASEIL
180 190 200 210 220 230
240 250 260 270 280 290
pF1KE6 QREVSVVDLVSHASVWLFRGDFVMDYPRPIMPNMVFIGGINCANGKPLSQEFEAYINASG
: :.. :: ::.:.::.: :::.:::.:.::::.::::::: .:::: .::::::::::
NP_061 QTPVTAYDLYSHTSIWLLRTDFVLDYPKPVMPNMIFIGGINCHQGKPLPMEFEAYINASG
240 250 260 270 280 290
300 310 320 330 340 350
pF1KE6 EHGIVVFSLGSMVSEIPEKKAMAIADALGKIPQTVLWRYTGTRPSNLANNTILVKWLPQN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 EHGIVVFSLGSMVSEIPEKKAMAIADALGKIPQTVLWRYTGTRPSNLANNTILVKWLPQN
300 310 320 330 340 350
360 370 380 390 400 410
pF1KE6 DLLGHPMTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMDNAKRMETKGAGVTLNVLEM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 DLLGHPMTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMDNAKRMETKGAGVTLNVLEM
360 370 380 390 400 410
420 430 440 450 460 470
pF1KE6 TSEDLENALKAVINDKSYKENIMRLSSLHKDRPVEPLDLAVFWVEFVMRHKGAPHLRPAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 TSEDLENALKAVINDKSYKENIMRLSSLHKDRPVEPLDLAVFWVEFVMRHKGAPHLRPAA
420 430 440 450 460 470
480 490 500 510 520 530
pF1KE6 HDLTWYQYHSLDVIGFLLAVVLTVAFITFKCCAYGYRKCLGKKGRVKKAHKSKTH
:::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 HDLTWYQYHSLDVIGFLLAVVLTVAFITFKCCAYGYRKCLGKKGRVKKAHKSKTH
480 490 500 510 520 530
>>NP_061948 (OMIM: 606435) UDP-glucuronosyltransferase 1 (530 aa)
initn: 2360 init1: 2187 opt: 2369 Z-score: 2734.1 bits: 515.6 E(85289): 1.5e-145
Smith-Waterman score: 2369; 67.9% identity (82.7% similar) in 533 aa overlap (4-534:5-530)
10 20 30 40 50
pF1KE6 MATGLQVPLPQLATGLLLLLSVQPWAESGKVLVVPTDGSHWLSMREALRDLHARGHQVV
: :.: : . ::: . .::.::.:::: :::::..:. ... : :::.::
NP_061 MARAGWTSPVP-LCVCLLLTCG---FAEAGKLLVVPMDGSHWFTMQSVVEKLILRGHEVV
10 20 30 40 50
60 70 80 90 100 110
pF1KE6 VLTLEVNMYIKEENFFTLTTYAISWTQDEFDR--LLLGHTQSFFETEHLLMKFSRRMAIM
:. ::. ... :. ::. :.: .. .: ....:.: ... . :: :.
NP_061 VVMPEVSWQLERSLNCTVKTYSTSYTLEDQNREFMVFAHAQWKAQAQSI---FSLLMSSS
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE6 NNMSLIIHRSCVELLHNEALIRHLHATSFDVVLTDPFHLCAAVLAKYLSIPAVFFLRNIP
... .. : :.... :...:. .:::.:. ::: :. ..:::.:.:.: : :.:
NP_061 SGFLDLFFSHCRSLFNDRKLVEYLKESSFDAVFLDPFDTCGLIVAKYFSLPSVVFTRGIF
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE6 CDLDFKGTQCPNPSSYIPRLLTTNSDHMTFLQRVKNMLYPLALSYLCHAVSAPYASLASE
: .:.::: : ::.: : :: ::: .:: : . : .:. . .:::
NP_061 CHHLEEGAQCPAPLSYVPNDLLGFSDAMTFKERVWNHIVHLEDHLFCQYLFRNALEIASE
180 190 200 210 220 230
240 250 260 270 280 290
pF1KE6 LFQREVSVVDLVSHASVWLFRGDFVMDYPRPIMPNMVFIGGINCANGKPLSQEFEAYINA
..: :.. :: ::.:.::.: :::.:::.:.::::.::::::: .:::: .::::::::
NP_061 ILQTPVTAYDLYSHTSIWLLRTDFVLDYPKPVMPNMIFIGGINCHQGKPLPMEFEAYINA
240 250 260 270 280 290
300 310 320 330 340 350
pF1KE6 SGEHGIVVFSLGSMVSEIPEKKAMAIADALGKIPQTVLWRYTGTRPSNLANNTILVKWLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 SGEHGIVVFSLGSMVSEIPEKKAMAIADALGKIPQTVLWRYTGTRPSNLANNTILVKWLP
300 310 320 330 340 350
360 370 380 390 400 410
pF1KE6 QNDLLGHPMTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMDNAKRMETKGAGVTLNVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 QNDLLGHPMTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMDNAKRMETKGAGVTLNVL
360 370 380 390 400 410
420 430 440 450 460 470
pF1KE6 EMTSEDLENALKAVINDKSYKENIMRLSSLHKDRPVEPLDLAVFWVEFVMRHKGAPHLRP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 EMTSEDLENALKAVINDKSYKENIMRLSSLHKDRPVEPLDLAVFWVEFVMRHKGAPHLRP
420 430 440 450 460 470
480 490 500 510 520 530
pF1KE6 AAHDLTWYQYHSLDVIGFLLAVVLTVAFITFKCCAYGYRKCLGKKGRVKKAHKSKTH
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 AAHDLTWYQYHSLDVIGFLLAVVLTVAFITFKCCAYGYRKCLGKKGRVKKAHKSKTH
480 490 500 510 520 530
>>NP_001063 (OMIM: 606431) UDP-glucuronosyltransferase 1 (532 aa)
initn: 2353 init1: 2353 opt: 2368 Z-score: 2733.0 bits: 515.4 E(85289): 1.7e-145
Smith-Waterman score: 2368; 67.9% identity (83.7% similar) in 526 aa overlap (11-534:9-532)
10 20 30 40 50 60
pF1KE6 MATGLQVPLPQLATGLLLLLSVQPWAESGKVLVVPTDGSHWLSMREALRDLHARGHQVVV
: .. ...:.. . . :.:::: ::::::::.. .. : :::..::
NP_001 MACLLRSFQRISAGVFFLALWGMVVGDKLLVVPQDGSHWLSMKDIVEVLSDRGHEIVV
10 20 30 40 50
70 80 90 100 110 120
pF1KE6 LTLEVNMYIKEENFFTLTTYAISWTQDEFDRLLLGHTQSFFETEHLLMKFSRRMAIMNNM
.. :::. .:: ...: : . . :.:. . .. : . .: . . :::
NP_001 VVPEVNLLLKESKYYTRKIYPVPYDQEELKNRYQSFGNNHFAERSFLT--APQTEYRNNM
60 70 80 90 100 110
130 140 150 160 170
pF1KE6 SLI--IHRSCVELLHNEALIRHLHATSFDVVLTDPFHLCAAVLAKYLSIPAVFFLRNIPC
.: .: ::... . .. ..::...::: :...::.::..:.:...:..::
NP_001 IVIGLYFINCQSLLQDRDTLNFFKESKFDALFTDPALPCGVILAEYLGLPSVYLFRGFPC
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE6 DLDFKGTQCPNPSSYIPRLLTTNSDHMTFLQRVKNMLYPLALSYLCHAVSAPYASLASEL
.:. .. :.: ::::: : :::::: ::: :.: : :: . . . : ::: .
NP_001 SLEHTFSRSPDPVSYIPRCYTKFSDHMTFSQRVANFLVNLLEPYLFYCLFSKYEELASAV
180 190 200 210 220 230
240 250 260 270 280 290
pF1KE6 FQREVSVVDLVSHASVWLFRGDFVMDYPRPIMPNMVFIGGINCANGKPLSQEFEAYINAS
..:.:... : ...::::.: :::..::::.:::::::::::: . : ::::::::::::
NP_001 LKRDVDIITLYQKVSVWLLRYDFVLEYPRPVMPNMVFIGGINCKKRKDLSQEFEAYINAS
240 250 260 270 280 290
300 310 320 330 340 350
pF1KE6 GEHGIVVFSLGSMVSEIPEKKAMAIADALGKIPQTVLWRYTGTRPSNLANNTILVKWLPQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GEHGIVVFSLGSMVSEIPEKKAMAIADALGKIPQTVLWRYTGTRPSNLANNTILVKWLPQ
300 310 320 330 340 350
360 370 380 390 400 410
pF1KE6 NDLLGHPMTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMDNAKRMETKGAGVTLNVLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 NDLLGHPMTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMDNAKRMETKGAGVTLNVLE
360 370 380 390 400 410
420 430 440 450 460 470
pF1KE6 MTSEDLENALKAVINDKSYKENIMRLSSLHKDRPVEPLDLAVFWVEFVMRHKGAPHLRPA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MTSEDLENALKAVINDKSYKENIMRLSSLHKDRPVEPLDLAVFWVEFVMRHKGAPHLRPA
420 430 440 450 460 470
480 490 500 510 520 530
pF1KE6 AHDLTWYQYHSLDVIGFLLAVVLTVAFITFKCCAYGYRKCLGKKGRVKKAHKSKTH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AHDLTWYQYHSLDVIGFLLAVVLTVAFITFKCCAYGYRKCLGKKGRVKKAHKSKTH
480 490 500 510 520 530
>>NP_061950 (OMIM: 606432) UDP-glucuronosyltransferase 1 (530 aa)
initn: 2359 init1: 2188 opt: 2363 Z-score: 2727.2 bits: 514.3 E(85289): 3.6e-145
Smith-Waterman score: 2363; 68.6% identity (82.7% similar) in 525 aa overlap (14-534:7-530)
10 20 30 40 50
pF1KE6 MATGLQVPLPQLATGLL----LLLSVQPWAESGKVLVVPTDGSHWLSMREALRDLHARGH
:::: :: . .:..::.:::: :::::..:. ... : :::
NP_061 MARAGWTGLLPLYVCLLLTCGFAKAGKLLVVPMDGSHWFTMQSVVEKLILRGH
10 20 30 40 50
60 70 80 90 100 110
pF1KE6 QVVVLTLEVNMYIKEENFFTLTTYAISWTQDEFDRLLLGHTQSFFETEHLLMKFSRRMAI
.:::. ::. . . :. ::. :.: .. :: .. ... . : : :: .
NP_061 EVVVVMPEVSWQLGRSLNCTVKTYSTSYTLEDQDREFMVFADARW-TAPLRSAFSLLTSS
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE6 MNNMSLIIHRSCVELLHNEALIRHLHATSFDVVLTDPFHLCAAVLAKYLSIPAVFFLRNI
:.. .. .: :.... :...:. . ::.:. ::: :. ..:::.:.:.: : :.:
NP_061 SNGIFDLFFSNCRSLFNDRKLVEYLKESCFDAVFLDPFDACGLIVAKYFSLPSVVFARGI
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE6 PCDLDFKGTQCPNPSSYIPRLLTTNSDHMTFLQRVKNMLYPLALSYLCHAVSAPYASLAS
: .:.::: : ::.:::: :: ::: .:: : .. : .: .::
NP_061 FCHYLEEGAQCPAPLSYVPRLLLGFSDAMTFKERVWNHIMHLEEHLFCPYFFKNVLEIAS
180 190 200 210 220 230
240 250 260 270 280 290
pF1KE6 ELFQREVSVVDLVSHASVWLFRGDFVMDYPRPIMPNMVFIGGINCANGKPLSQEFEAYIN
:..: :.. :: ::.:.::.: :::..::.:.::::.::::::: .:::. .:::::::
NP_061 EILQTPVTAYDLYSHTSIWLLRTDFVLEYPKPVMPNMIFIGGINCHQGKPVPMEFEAYIN
240 250 260 270 280 290
300 310 320 330 340 350
pF1KE6 ASGEHGIVVFSLGSMVSEIPEKKAMAIADALGKIPQTVLWRYTGTRPSNLANNTILVKWL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 ASGEHGIVVFSLGSMVSEIPEKKAMAIADALGKIPQTVLWRYTGTRPSNLANNTILVKWL
300 310 320 330 340 350
360 370 380 390 400 410
pF1KE6 PQNDLLGHPMTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMDNAKRMETKGAGVTLNV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 PQNDLLGHPMTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMDNAKRMETKGAGVTLNV
360 370 380 390 400 410
420 430 440 450 460 470
pF1KE6 LEMTSEDLENALKAVINDKSYKENIMRLSSLHKDRPVEPLDLAVFWVEFVMRHKGAPHLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 LEMTSEDLENALKAVINDKSYKENIMRLSSLHKDRPVEPLDLAVFWVEFVMRHKGAPHLR
420 430 440 450 460 470
480 490 500 510 520 530
pF1KE6 PAAHDLTWYQYHSLDVIGFLLAVVLTVAFITFKCCAYGYRKCLGKKGRVKKAHKSKTH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 PAAHDLTWYQYHSLDVIGFLLAVVLTVAFITFKCCAYGYRKCLGKKGRVKKAHKSKTH
480 490 500 510 520 530
>>NP_995584 (OMIM: 606431) UDP-glucuronosyltransferase 1 (265 aa)
initn: 1751 init1: 1751 opt: 1751 Z-score: 2026.0 bits: 383.6 E(85289): 4.1e-106
Smith-Waterman score: 1751; 98.5% identity (98.9% similar) in 265 aa overlap (270-534:1-265)
240 250 260 270 280 290
pF1KE6 QREVSVVDLVSHASVWLFRGDFVMDYPRPIMPNMVFIGGINCANGKPLSQEFEAYINASG
:::::::::::: . : :::::::::::::
NP_995 MPNMVFIGGINCKKRKDLSQEFEAYINASG
10 20 30
300 310 320 330 340 350
pF1KE6 EHGIVVFSLGSMVSEIPEKKAMAIADALGKIPQTVLWRYTGTRPSNLANNTILVKWLPQN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_995 EHGIVVFSLGSMVSEIPEKKAMAIADALGKIPQTVLWRYTGTRPSNLANNTILVKWLPQN
40 50 60 70 80 90
360 370 380 390 400 410
pF1KE6 DLLGHPMTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMDNAKRMETKGAGVTLNVLEM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_995 DLLGHPMTRAFITHAGSHGVYESICNGVPMVMMPLFGDQMDNAKRMETKGAGVTLNVLEM
100 110 120 130 140 150
420 430 440 450 460 470
pF1KE6 TSEDLENALKAVINDKSYKENIMRLSSLHKDRPVEPLDLAVFWVEFVMRHKGAPHLRPAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_995 TSEDLENALKAVINDKSYKENIMRLSSLHKDRPVEPLDLAVFWVEFVMRHKGAPHLRPAA
160 170 180 190 200 210
480 490 500 510 520 530
pF1KE6 HDLTWYQYHSLDVIGFLLAVVLTVAFITFKCCAYGYRKCLGKKGRVKKAHKSKTH
:::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_995 HDLTWYQYHSLDVIGFLLAVVLTVAFITFKCCAYGYRKCLGKKGRVKKAHKSKTH
220 230 240 250 260
534 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Nov 8 13:25:02 2016 done: Tue Nov 8 13:25:03 2016
Total Scan time: 6.780 Total Display time: 0.080
Function used was FASTA [36.3.4 Apr, 2011]