Result of FASTA (omim) for
pFN21AE6447
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE6447, 506 aa
1>>>pF1KE6447 506 - 506 aa - 506 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 4.8347+/-0.000419; mu= 21.2116+/- 0.026
mean_var=65.9503+/-13.227, 0's: 0 Z-trim(109.8): 36 B-trim: 176 in 1/52
Lambda= 0.157930
statistics sampled from 18069 (18092) to 18069 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.587), E-opt: 0.2 (0.212), width: 16
Scan time: 7.370
The best scores are: opt bits E(85289)
NP_036340 (OMIM: 600783,614926) probable histidine ( 506) 3359 774.7 0
XP_011535921 (OMIM: 600783,614926) PREDICTED: prob ( 512) 3337 769.7 0
NP_001265660 (OMIM: 600783,614926) probable histid ( 481) 2950 681.5 1.5e-195
XP_016864777 (OMIM: 600783,614926) PREDICTED: prob ( 436) 2883 666.2 5.5e-191
XP_016864778 (OMIM: 600783,614926) PREDICTED: prob ( 436) 2883 666.2 5.5e-191
NP_001276023 (OMIM: 142810,614504,616625) histidin ( 480) 2466 571.2 2.3e-162
NP_002100 (OMIM: 142810,614504,616625) histidine-- ( 509) 2466 571.2 2.5e-162
NP_001244969 (OMIM: 142810,614504,616625) histidin ( 469) 2210 512.9 8.3e-145
NP_001265661 (OMIM: 600783,614926) probable histid ( 362) 2172 504.1 2.8e-142
XP_016864781 (OMIM: 600783,614926) PREDICTED: prob ( 286) 1861 433.2 4.9e-121
XP_016864780 (OMIM: 600783,614926) PREDICTED: prob ( 286) 1861 433.2 4.9e-121
XP_016864779 (OMIM: 600783,614926) PREDICTED: prob ( 286) 1861 433.2 4.9e-121
NP_001276021 (OMIM: 142810,614504,616625) histidin ( 435) 1816 423.1 8.3e-118
NP_001276022 (OMIM: 142810,614504,616625) histidin ( 395) 1815 422.8 9e-118
NP_001244971 (OMIM: 142810,614504,616625) histidin ( 449) 1815 422.8 1e-117
NP_001244970 (OMIM: 142810,614504,616625) histidin ( 489) 1815 422.9 1.1e-117
XP_016864776 (OMIM: 600783,614926) PREDICTED: prob ( 473) 1708 398.5 2.3e-110
XP_011535922 (OMIM: 600783,614926) PREDICTED: prob ( 479) 1708 398.5 2.3e-110
XP_011519901 (OMIM: 234810,609280) PREDICTED: eIF- (1611) 445 111.1 2.4e-23
XP_005254449 (OMIM: 234810,609280) PREDICTED: eIF- (1626) 445 111.1 2.5e-23
NP_001013725 (OMIM: 234810,609280) eIF-2-alpha kin (1649) 445 111.1 2.5e-23
XP_016877708 (OMIM: 234810,609280) PREDICTED: eIF- (1554) 269 71.0 2.8e-11
XP_011519902 (OMIM: 234810,609280) PREDICTED: eIF- (1592) 269 71.0 2.9e-11
>>NP_036340 (OMIM: 600783,614926) probable histidine--tR (506 aa)
initn: 3359 init1: 3359 opt: 3359 Z-score: 4135.1 bits: 774.7 E(85289): 0
Smith-Waterman score: 3359; 100.0% identity (100.0% similar) in 506 aa overlap (1-506:1-506)
10 20 30 40 50 60
pF1KE6 MPLLGLLPRRAWASLLSQLLRPPCASCTGAVRCQSQVAEAVLTSQLKAHQEKPNFIIKTP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 MPLLGLLPRRAWASLLSQLLRPPCASCTGAVRCQSQVAEAVLTSQLKAHQEKPNFIIKTP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 KGTRDLSPQHMVVREKILDLVISCFKRHGAKGMDTPAFELKETLTEKYGEDSGLMYDLKD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 KGTRDLSPQHMVVREKILDLVISCFKRHGAKGMDTPAFELKETLTEKYGEDSGLMYDLKD
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 QGGELLSLRYDLTVPFARYLAMNKVKKMKRYHVGKVWRRESPTIVQGRYREFCQCDFDIA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 QGGELLSLRYDLTVPFARYLAMNKVKKMKRYHVGKVWRRESPTIVQGRYREFCQCDFDIA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE6 GQFDPMIPDAECLKIMCEILSGLQLGDFLIKVNDRRIVDGMFAVCGVPESKFRAICSSID
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 GQFDPMIPDAECLKIMCEILSGLQLGDFLIKVNDRRIVDGMFAVCGVPESKFRAICSSID
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE6 KLDKMAWKDVRHEMVVKKGLAPEVADRIGDYVQCHGGVSLVEQMFQDPRLSQNKQALEGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 KLDKMAWKDVRHEMVVKKGLAPEVADRIGDYVQCHGGVSLVEQMFQDPRLSQNKQALEGL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE6 GDLKLLFEYLTLFGIADKISFDLSLARGLDYYTGVIYEAVLLQTPTQAGEEPLNVGSVAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 GDLKLLFEYLTLFGIADKISFDLSLARGLDYYTGVIYEAVLLQTPTQAGEEPLNVGSVAA
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE6 GGRYDGLVGMFDPKGHKVPCVGLSIGVERIFYIVEQRMKTKGEKVRTTETQVFVATPQKN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 GGRYDGLVGMFDPKGHKVPCVGLSIGVERIFYIVEQRMKTKGEKVRTTETQVFVATPQKN
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE6 FLQERLKLIAELWDSGIKAEMLYKNNPKLLTQLHYCESTGIPLVVIIGEQELKEGVIKIR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 FLQERLKLIAELWDSGIKAEMLYKNNPKLLTQLHYCESTGIPLVVIIGEQELKEGVIKIR
430 440 450 460 470 480
490 500
pF1KE6 SVASREEVAIKRENFVAEIQKRLSES
::::::::::::::::::::::::::
NP_036 SVASREEVAIKRENFVAEIQKRLSES
490 500
>>XP_011535921 (OMIM: 600783,614926) PREDICTED: probable (512 aa)
initn: 3110 init1: 3110 opt: 3337 Z-score: 4107.9 bits: 769.7 E(85289): 0
Smith-Waterman score: 3337; 98.8% identity (98.8% similar) in 512 aa overlap (1-506:1-512)
10 20 30 40 50
pF1KE6 MPLLGLLPRRAWASLLSQLLRPPCASCTGAVRCQSQ------VAEAVLTSQLKAHQEKPN
:::::::::::::::::::::::::::::::::::: ::::::::::::::::::
XP_011 MPLLGLLPRRAWASLLSQLLRPPCASCTGAVRCQSQGEESLQVAEAVLTSQLKAHQEKPN
10 20 30 40 50 60
60 70 80 90 100 110
pF1KE6 FIIKTPKGTRDLSPQHMVVREKILDLVISCFKRHGAKGMDTPAFELKETLTEKYGEDSGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FIIKTPKGTRDLSPQHMVVREKILDLVISCFKRHGAKGMDTPAFELKETLTEKYGEDSGL
70 80 90 100 110 120
120 130 140 150 160 170
pF1KE6 MYDLKDQGGELLSLRYDLTVPFARYLAMNKVKKMKRYHVGKVWRRESPTIVQGRYREFCQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MYDLKDQGGELLSLRYDLTVPFARYLAMNKVKKMKRYHVGKVWRRESPTIVQGRYREFCQ
130 140 150 160 170 180
180 190 200 210 220 230
pF1KE6 CDFDIAGQFDPMIPDAECLKIMCEILSGLQLGDFLIKVNDRRIVDGMFAVCGVPESKFRA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CDFDIAGQFDPMIPDAECLKIMCEILSGLQLGDFLIKVNDRRIVDGMFAVCGVPESKFRA
190 200 210 220 230 240
240 250 260 270 280 290
pF1KE6 ICSSIDKLDKMAWKDVRHEMVVKKGLAPEVADRIGDYVQCHGGVSLVEQMFQDPRLSQNK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ICSSIDKLDKMAWKDVRHEMVVKKGLAPEVADRIGDYVQCHGGVSLVEQMFQDPRLSQNK
250 260 270 280 290 300
300 310 320 330 340 350
pF1KE6 QALEGLGDLKLLFEYLTLFGIADKISFDLSLARGLDYYTGVIYEAVLLQTPTQAGEEPLN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 QALEGLGDLKLLFEYLTLFGIADKISFDLSLARGLDYYTGVIYEAVLLQTPTQAGEEPLN
310 320 330 340 350 360
360 370 380 390 400 410
pF1KE6 VGSVAAGGRYDGLVGMFDPKGHKVPCVGLSIGVERIFYIVEQRMKTKGEKVRTTETQVFV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VGSVAAGGRYDGLVGMFDPKGHKVPCVGLSIGVERIFYIVEQRMKTKGEKVRTTETQVFV
370 380 390 400 410 420
420 430 440 450 460 470
pF1KE6 ATPQKNFLQERLKLIAELWDSGIKAEMLYKNNPKLLTQLHYCESTGIPLVVIIGEQELKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ATPQKNFLQERLKLIAELWDSGIKAEMLYKNNPKLLTQLHYCESTGIPLVVIIGEQELKE
430 440 450 460 470 480
480 490 500
pF1KE6 GVIKIRSVASREEVAIKRENFVAEIQKRLSES
::::::::::::::::::::::::::::::::
XP_011 GVIKIRSVASREEVAIKRENFVAEIQKRLSES
490 500 510
>>NP_001265660 (OMIM: 600783,614926) probable histidine- (481 aa)
initn: 2950 init1: 2950 opt: 2950 Z-score: 3631.8 bits: 681.5 E(85289): 1.5e-195
Smith-Waterman score: 3144; 95.1% identity (95.1% similar) in 506 aa overlap (1-506:1-481)
10 20 30 40 50 60
pF1KE6 MPLLGLLPRRAWASLLSQLLRPPCASCTGAVRCQSQVAEAVLTSQLKAHQEKPNFIIKTP
::::::::::::::::::::::::::::::::::::
NP_001 MPLLGLLPRRAWASLLSQLLRPPCASCTGAVRCQSQ------------------------
10 20 30
70 80 90 100 110 120
pF1KE6 KGTRDLSPQHMVVREKILDLVISCFKRHGAKGMDTPAFELKETLTEKYGEDSGLMYDLKD
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 -GTRDLSPQHMVVREKILDLVISCFKRHGAKGMDTPAFELKETLTEKYGEDSGLMYDLKD
40 50 60 70 80 90
130 140 150 160 170 180
pF1KE6 QGGELLSLRYDLTVPFARYLAMNKVKKMKRYHVGKVWRRESPTIVQGRYREFCQCDFDIA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QGGELLSLRYDLTVPFARYLAMNKVKKMKRYHVGKVWRRESPTIVQGRYREFCQCDFDIA
100 110 120 130 140 150
190 200 210 220 230 240
pF1KE6 GQFDPMIPDAECLKIMCEILSGLQLGDFLIKVNDRRIVDGMFAVCGVPESKFRAICSSID
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GQFDPMIPDAECLKIMCEILSGLQLGDFLIKVNDRRIVDGMFAVCGVPESKFRAICSSID
160 170 180 190 200 210
250 260 270 280 290 300
pF1KE6 KLDKMAWKDVRHEMVVKKGLAPEVADRIGDYVQCHGGVSLVEQMFQDPRLSQNKQALEGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KLDKMAWKDVRHEMVVKKGLAPEVADRIGDYVQCHGGVSLVEQMFQDPRLSQNKQALEGL
220 230 240 250 260 270
310 320 330 340 350 360
pF1KE6 GDLKLLFEYLTLFGIADKISFDLSLARGLDYYTGVIYEAVLLQTPTQAGEEPLNVGSVAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GDLKLLFEYLTLFGIADKISFDLSLARGLDYYTGVIYEAVLLQTPTQAGEEPLNVGSVAA
280 290 300 310 320 330
370 380 390 400 410 420
pF1KE6 GGRYDGLVGMFDPKGHKVPCVGLSIGVERIFYIVEQRMKTKGEKVRTTETQVFVATPQKN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GGRYDGLVGMFDPKGHKVPCVGLSIGVERIFYIVEQRMKTKGEKVRTTETQVFVATPQKN
340 350 360 370 380 390
430 440 450 460 470 480
pF1KE6 FLQERLKLIAELWDSGIKAEMLYKNNPKLLTQLHYCESTGIPLVVIIGEQELKEGVIKIR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FLQERLKLIAELWDSGIKAEMLYKNNPKLLTQLHYCESTGIPLVVIIGEQELKEGVIKIR
400 410 420 430 440 450
490 500
pF1KE6 SVASREEVAIKRENFVAEIQKRLSES
::::::::::::::::::::::::::
NP_001 SVASREEVAIKRENFVAEIQKRLSES
460 470 480
>>XP_016864777 (OMIM: 600783,614926) PREDICTED: probable (436 aa)
initn: 2883 init1: 2883 opt: 2883 Z-score: 3549.9 bits: 666.2 E(85289): 5.5e-191
Smith-Waterman score: 2883; 100.0% identity (100.0% similar) in 436 aa overlap (71-506:1-436)
50 60 70 80 90 100
pF1KE6 VLTSQLKAHQEKPNFIIKTPKGTRDLSPQHMVVREKILDLVISCFKRHGAKGMDTPAFEL
::::::::::::::::::::::::::::::
XP_016 MVVREKILDLVISCFKRHGAKGMDTPAFEL
10 20 30
110 120 130 140 150 160
pF1KE6 KETLTEKYGEDSGLMYDLKDQGGELLSLRYDLTVPFARYLAMNKVKKMKRYHVGKVWRRE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KETLTEKYGEDSGLMYDLKDQGGELLSLRYDLTVPFARYLAMNKVKKMKRYHVGKVWRRE
40 50 60 70 80 90
170 180 190 200 210 220
pF1KE6 SPTIVQGRYREFCQCDFDIAGQFDPMIPDAECLKIMCEILSGLQLGDFLIKVNDRRIVDG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SPTIVQGRYREFCQCDFDIAGQFDPMIPDAECLKIMCEILSGLQLGDFLIKVNDRRIVDG
100 110 120 130 140 150
230 240 250 260 270 280
pF1KE6 MFAVCGVPESKFRAICSSIDKLDKMAWKDVRHEMVVKKGLAPEVADRIGDYVQCHGGVSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MFAVCGVPESKFRAICSSIDKLDKMAWKDVRHEMVVKKGLAPEVADRIGDYVQCHGGVSL
160 170 180 190 200 210
290 300 310 320 330 340
pF1KE6 VEQMFQDPRLSQNKQALEGLGDLKLLFEYLTLFGIADKISFDLSLARGLDYYTGVIYEAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VEQMFQDPRLSQNKQALEGLGDLKLLFEYLTLFGIADKISFDLSLARGLDYYTGVIYEAV
220 230 240 250 260 270
350 360 370 380 390 400
pF1KE6 LLQTPTQAGEEPLNVGSVAAGGRYDGLVGMFDPKGHKVPCVGLSIGVERIFYIVEQRMKT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LLQTPTQAGEEPLNVGSVAAGGRYDGLVGMFDPKGHKVPCVGLSIGVERIFYIVEQRMKT
280 290 300 310 320 330
410 420 430 440 450 460
pF1KE6 KGEKVRTTETQVFVATPQKNFLQERLKLIAELWDSGIKAEMLYKNNPKLLTQLHYCESTG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KGEKVRTTETQVFVATPQKNFLQERLKLIAELWDSGIKAEMLYKNNPKLLTQLHYCESTG
340 350 360 370 380 390
470 480 490 500
pF1KE6 IPLVVIIGEQELKEGVIKIRSVASREEVAIKRENFVAEIQKRLSES
::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IPLVVIIGEQELKEGVIKIRSVASREEVAIKRENFVAEIQKRLSES
400 410 420 430
>>XP_016864778 (OMIM: 600783,614926) PREDICTED: probable (436 aa)
initn: 2883 init1: 2883 opt: 2883 Z-score: 3549.9 bits: 666.2 E(85289): 5.5e-191
Smith-Waterman score: 2883; 100.0% identity (100.0% similar) in 436 aa overlap (71-506:1-436)
50 60 70 80 90 100
pF1KE6 VLTSQLKAHQEKPNFIIKTPKGTRDLSPQHMVVREKILDLVISCFKRHGAKGMDTPAFEL
::::::::::::::::::::::::::::::
XP_016 MVVREKILDLVISCFKRHGAKGMDTPAFEL
10 20 30
110 120 130 140 150 160
pF1KE6 KETLTEKYGEDSGLMYDLKDQGGELLSLRYDLTVPFARYLAMNKVKKMKRYHVGKVWRRE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KETLTEKYGEDSGLMYDLKDQGGELLSLRYDLTVPFARYLAMNKVKKMKRYHVGKVWRRE
40 50 60 70 80 90
170 180 190 200 210 220
pF1KE6 SPTIVQGRYREFCQCDFDIAGQFDPMIPDAECLKIMCEILSGLQLGDFLIKVNDRRIVDG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 SPTIVQGRYREFCQCDFDIAGQFDPMIPDAECLKIMCEILSGLQLGDFLIKVNDRRIVDG
100 110 120 130 140 150
230 240 250 260 270 280
pF1KE6 MFAVCGVPESKFRAICSSIDKLDKMAWKDVRHEMVVKKGLAPEVADRIGDYVQCHGGVSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MFAVCGVPESKFRAICSSIDKLDKMAWKDVRHEMVVKKGLAPEVADRIGDYVQCHGGVSL
160 170 180 190 200 210
290 300 310 320 330 340
pF1KE6 VEQMFQDPRLSQNKQALEGLGDLKLLFEYLTLFGIADKISFDLSLARGLDYYTGVIYEAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VEQMFQDPRLSQNKQALEGLGDLKLLFEYLTLFGIADKISFDLSLARGLDYYTGVIYEAV
220 230 240 250 260 270
350 360 370 380 390 400
pF1KE6 LLQTPTQAGEEPLNVGSVAAGGRYDGLVGMFDPKGHKVPCVGLSIGVERIFYIVEQRMKT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LLQTPTQAGEEPLNVGSVAAGGRYDGLVGMFDPKGHKVPCVGLSIGVERIFYIVEQRMKT
280 290 300 310 320 330
410 420 430 440 450 460
pF1KE6 KGEKVRTTETQVFVATPQKNFLQERLKLIAELWDSGIKAEMLYKNNPKLLTQLHYCESTG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KGEKVRTTETQVFVATPQKNFLQERLKLIAELWDSGIKAEMLYKNNPKLLTQLHYCESTG
340 350 360 370 380 390
470 480 490 500
pF1KE6 IPLVVIIGEQELKEGVIKIRSVASREEVAIKRENFVAEIQKRLSES
::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IPLVVIIGEQELKEGVIKIRSVASREEVAIKRENFVAEIQKRLSES
400 410 420 430
>>NP_001276023 (OMIM: 142810,614504,616625) histidine--t (480 aa)
initn: 2460 init1: 2460 opt: 2466 Z-score: 3035.8 bits: 571.2 E(85289): 2.3e-162
Smith-Waterman score: 2466; 76.3% identity (93.9% similar) in 473 aa overlap (34-505:3-475)
10 20 30 40 50 60
pF1KE6 LGLLPRRAWASLLSQLLRPPCASCTGAVRCQSQVAEAV-LTSQLKAHQEKPNFIIKTPKG
. .::. . : .:: . : .:..:::::
NP_001 MIEEEVAKLLKLKAQLGPDESKQKFVLKTPKG
10 20 30
70 80 90 100 110 120
pF1KE6 TRDLSPQHMVVREKILDLVISCFKRHGAKGMDTPAFELKETLTEKYGEDSGLMYDLKDQG
::: ::..:.::::..:..: :::::::. .:::.::::::: :::::: :.:::::::
NP_001 TRDYSPRQMAVREKVFDVIIRCFKRHGAEVIDTPVFELKETLMGKYGEDSKLIYDLKDQG
40 50 60 70 80 90
130 140 150 160 170 180
pF1KE6 GELLSLRYDLTVPFARYLAMNKVKKMKRYHVGKVWRRESPTIVQGRYREFCQCDFDIAGQ
::::::::::::::::::::::. ..::::..::.::..:....:::::: ::::::::.
NP_001 GELLSLRYDLTVPFARYLAMNKLTNIKRYHIAKVYRRDNPAMTRGRYREFYQCDFDIAGN
100 110 120 130 140 150
190 200 210 220 230 240
pF1KE6 FDPMIPDAECLKIMCEILSGLQLGDFLIKVNDRRIVDGMFAVCGVPESKFRAICSSIDKL
:::::::::::::::::::.::.::::.:::::::.:::::.::: .::::.::::.:::
NP_001 FDPMIPDAECLKIMCEILSSLQIGDFLVKVNDRRILDGMFAICGVSDSKFRTICSSVDKL
160 170 180 190 200 210
250 260 270 280 290 300
pF1KE6 DKMAWKDVRHEMVVKKGLAPEVADRIGDYVQCHGGVSLVEQMFQDPRLSQNKQALEGLGD
::..:..:..::: .:::::::::::::::: :::::::::..:::.:::::::::::::
NP_001 DKVSWEEVKNEMVGEKGLAPEVADRIGDYVQQHGGVSLVEQLLQDPKLSQNKQALEGLGD
220 230 240 250 260 270
310 320 330 340 350 360
pF1KE6 LKLLFEYLTLFGIADKISFDLSLARGLDYYTGVIYEAVLLQTPTQAGEEPLNVGSVAAGG
::::::::::::: :::::::::::::::::::::::::::::.:::::::.::::::::
NP_001 LKLLFEYLTLFGIDDKISFDLSLARGLDYYTGVIYEAVLLQTPAQAGEEPLGVGSVAAGG
280 290 300 310 320 330
370 380 390 400 410 420
pF1KE6 RYDGLVGMFDPKGHKVPCVGLSIGVERIFYIVEQRMKTKGEKVRTTETQVFVATPQKNFL
:::::::::::::.::::::::::::::: :::::... ::.:::::::.::. ::..:
NP_001 RYDGLVGMFDPKGRKVPCVGLSIGVERIFSIVEQRLEALEEKIRTTETQVLVASAQKKLL
340 350 360 370 380 390
430 440 450 460 470 480
pF1KE6 QERLKLIAELWDSGIKAEMLYKNNPKLLTQLHYCESTGIPLVVIIGEQELKEGVIKIRSV
.:::::..::::.:::::.:::.:::::.::.::: .:::::.::::::::.::::.:::
NP_001 EERLKLVSELWDAGIKAELLYKKNPKLLNQLQYCEEAGIPLVAIIGEQELKDGVIKLRSV
400 410 420 430 440 450
490 500
pF1KE6 ASREEVAIKRENFVAEIQKRLSES
.::::: ..::..: ::..: ..
NP_001 TSREEVDVRREDLVEEIKRRTGQPLCIC
460 470 480
>>NP_002100 (OMIM: 142810,614504,616625) histidine--tRNA (509 aa)
initn: 2489 init1: 2460 opt: 2466 Z-score: 3035.4 bits: 571.2 E(85289): 2.5e-162
Smith-Waterman score: 2466; 76.3% identity (93.9% similar) in 473 aa overlap (34-505:32-504)
10 20 30 40 50 60
pF1KE6 LGLLPRRAWASLLSQLLRPPCASCTGAVRCQSQVAEAV-LTSQLKAHQEKPNFIIKTPKG
. .::. . : .:: . : .:..:::::
NP_002 AERAALEELVKLQGERVRGLKQQKASAELIEEEVAKLLKLKAQLGPDESKQKFVLKTPKG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 TRDLSPQHMVVREKILDLVISCFKRHGAKGMDTPAFELKETLTEKYGEDSGLMYDLKDQG
::: ::..:.::::..:..: :::::::. .:::.::::::: :::::: :.:::::::
NP_002 TRDYSPRQMAVREKVFDVIIRCFKRHGAEVIDTPVFELKETLMGKYGEDSKLIYDLKDQG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 GELLSLRYDLTVPFARYLAMNKVKKMKRYHVGKVWRRESPTIVQGRYREFCQCDFDIAGQ
::::::::::::::::::::::. ..::::..::.::..:....:::::: ::::::::.
NP_002 GELLSLRYDLTVPFARYLAMNKLTNIKRYHIAKVYRRDNPAMTRGRYREFYQCDFDIAGN
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE6 FDPMIPDAECLKIMCEILSGLQLGDFLIKVNDRRIVDGMFAVCGVPESKFRAICSSIDKL
:::::::::::::::::::.::.::::.:::::::.:::::.::: .::::.::::.:::
NP_002 FDPMIPDAECLKIMCEILSSLQIGDFLVKVNDRRILDGMFAICGVSDSKFRTICSSVDKL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE6 DKMAWKDVRHEMVVKKGLAPEVADRIGDYVQCHGGVSLVEQMFQDPRLSQNKQALEGLGD
::..:..:..::: .:::::::::::::::: :::::::::..:::.:::::::::::::
NP_002 DKVSWEEVKNEMVGEKGLAPEVADRIGDYVQQHGGVSLVEQLLQDPKLSQNKQALEGLGD
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE6 LKLLFEYLTLFGIADKISFDLSLARGLDYYTGVIYEAVLLQTPTQAGEEPLNVGSVAAGG
::::::::::::: :::::::::::::::::::::::::::::.:::::::.::::::::
NP_002 LKLLFEYLTLFGIDDKISFDLSLARGLDYYTGVIYEAVLLQTPAQAGEEPLGVGSVAAGG
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE6 RYDGLVGMFDPKGHKVPCVGLSIGVERIFYIVEQRMKTKGEKVRTTETQVFVATPQKNFL
:::::::::::::.::::::::::::::: :::::... ::.:::::::.::. ::..:
NP_002 RYDGLVGMFDPKGRKVPCVGLSIGVERIFSIVEQRLEALEEKIRTTETQVLVASAQKKLL
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE6 QERLKLIAELWDSGIKAEMLYKNNPKLLTQLHYCESTGIPLVVIIGEQELKEGVIKIRSV
.:::::..::::.:::::.:::.:::::.::.::: .:::::.::::::::.::::.:::
NP_002 EERLKLVSELWDAGIKAELLYKKNPKLLNQLQYCEEAGIPLVAIIGEQELKDGVIKLRSV
430 440 450 460 470 480
490 500
pF1KE6 ASREEVAIKRENFVAEIQKRLSES
.::::: ..::..: ::..: ..
NP_002 TSREEVDVRREDLVEEIKRRTGQPLCIC
490 500
>>NP_001244969 (OMIM: 142810,614504,616625) histidine--t (469 aa)
initn: 2253 init1: 2210 opt: 2210 Z-score: 2720.7 bits: 512.9 E(85289): 8.3e-145
Smith-Waterman score: 2210; 80.0% identity (95.8% similar) in 405 aa overlap (101-505:60-464)
80 90 100 110 120 130
pF1KE6 MVVREKILDLVISCFKRHGAKGMDTPAFELKETLTEKYGEDSGLMYDLKDQGGELLSLRY
:::: :::::: :.:::::::::::::::
NP_001 LIEEEVAKLLKLKAQLGPDESKQKFVLKTPKETLMGKYGEDSKLIYDLKDQGGELLSLRY
30 40 50 60 70 80
140 150 160 170 180 190
pF1KE6 DLTVPFARYLAMNKVKKMKRYHVGKVWRRESPTIVQGRYREFCQCDFDIAGQFDPMIPDA
::::::::::::::. ..::::..::.::..:....:::::: ::::::::.::::::::
NP_001 DLTVPFARYLAMNKLTNIKRYHIAKVYRRDNPAMTRGRYREFYQCDFDIAGNFDPMIPDA
90 100 110 120 130 140
200 210 220 230 240 250
pF1KE6 ECLKIMCEILSGLQLGDFLIKVNDRRIVDGMFAVCGVPESKFRAICSSIDKLDKMAWKDV
:::::::::::.::.::::.:::::::.:::::.::: .::::.::::.:::::..:..:
NP_001 ECLKIMCEILSSLQIGDFLVKVNDRRILDGMFAICGVSDSKFRTICSSVDKLDKVSWEEV
150 160 170 180 190 200
260 270 280 290 300 310
pF1KE6 RHEMVVKKGLAPEVADRIGDYVQCHGGVSLVEQMFQDPRLSQNKQALEGLGDLKLLFEYL
..::: .:::::::::::::::: :::::::::..:::.:::::::::::::::::::::
NP_001 KNEMVGEKGLAPEVADRIGDYVQQHGGVSLVEQLLQDPKLSQNKQALEGLGDLKLLFEYL
210 220 230 240 250 260
320 330 340 350 360 370
pF1KE6 TLFGIADKISFDLSLARGLDYYTGVIYEAVLLQTPTQAGEEPLNVGSVAAGGRYDGLVGM
::::: :::::::::::::::::::::::::::::.:::::::.::::::::::::::::
NP_001 TLFGIDDKISFDLSLARGLDYYTGVIYEAVLLQTPAQAGEEPLGVGSVAAGGRYDGLVGM
270 280 290 300 310 320
380 390 400 410 420 430
pF1KE6 FDPKGHKVPCVGLSIGVERIFYIVEQRMKTKGEKVRTTETQVFVATPQKNFLQERLKLIA
:::::.::::::::::::::: :::::... ::.:::::::.::. ::..:.:::::..
NP_001 FDPKGRKVPCVGLSIGVERIFSIVEQRLEALEEKIRTTETQVLVASAQKKLLEERLKLVS
330 340 350 360 370 380
440 450 460 470 480 490
pF1KE6 ELWDSGIKAEMLYKNNPKLLTQLHYCESTGIPLVVIIGEQELKEGVIKIRSVASREEVAI
::::.:::::.:::.:::::.::.::: .:::::.::::::::.::::.:::.::::: .
NP_001 ELWDAGIKAELLYKKNPKLLNQLQYCEEAGIPLVAIIGEQELKDGVIKLRSVTSREEVDV
390 400 410 420 430 440
500
pF1KE6 KRENFVAEIQKRLSES
.::..: ::..: ..
NP_001 RREDLVEEIKRRTGQPLCIC
450 460
>>NP_001265661 (OMIM: 600783,614926) probable histidine- (362 aa)
initn: 2172 init1: 2172 opt: 2172 Z-score: 2675.4 bits: 504.1 E(85289): 2.8e-142
Smith-Waterman score: 2219; 83.0% identity (83.0% similar) in 436 aa overlap (71-506:1-362)
50 60 70 80 90 100
pF1KE6 VLTSQLKAHQEKPNFIIKTPKGTRDLSPQHMVVREKILDLVISCFKRHGAKGMDTPAFEL
::::::::::::::::::::::::::::::
NP_001 MVVREKILDLVISCFKRHGAKGMDTPAFEL
10 20 30
110 120 130 140 150 160
pF1KE6 KETLTEKYGEDSGLMYDLKDQGGELLSLRYDLTVPFARYLAMNKVKKMKRYHVGKVWRRE
:
NP_001 K-----------------------------------------------------------
170 180 190 200 210 220
pF1KE6 SPTIVQGRYREFCQCDFDIAGQFDPMIPDAECLKIMCEILSGLQLGDFLIKVNDRRIVDG
:::::::::::::::::::::::::::::::::::::::::::::
NP_001 ---------------DFDIAGQFDPMIPDAECLKIMCEILSGLQLGDFLIKVNDRRIVDG
40 50 60 70
230 240 250 260 270 280
pF1KE6 MFAVCGVPESKFRAICSSIDKLDKMAWKDVRHEMVVKKGLAPEVADRIGDYVQCHGGVSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MFAVCGVPESKFRAICSSIDKLDKMAWKDVRHEMVVKKGLAPEVADRIGDYVQCHGGVSL
80 90 100 110 120 130
290 300 310 320 330 340
pF1KE6 VEQMFQDPRLSQNKQALEGLGDLKLLFEYLTLFGIADKISFDLSLARGLDYYTGVIYEAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VEQMFQDPRLSQNKQALEGLGDLKLLFEYLTLFGIADKISFDLSLARGLDYYTGVIYEAV
140 150 160 170 180 190
350 360 370 380 390 400
pF1KE6 LLQTPTQAGEEPLNVGSVAAGGRYDGLVGMFDPKGHKVPCVGLSIGVERIFYIVEQRMKT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LLQTPTQAGEEPLNVGSVAAGGRYDGLVGMFDPKGHKVPCVGLSIGVERIFYIVEQRMKT
200 210 220 230 240 250
410 420 430 440 450 460
pF1KE6 KGEKVRTTETQVFVATPQKNFLQERLKLIAELWDSGIKAEMLYKNNPKLLTQLHYCESTG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KGEKVRTTETQVFVATPQKNFLQERLKLIAELWDSGIKAEMLYKNNPKLLTQLHYCESTG
260 270 280 290 300 310
470 480 490 500
pF1KE6 IPLVVIIGEQELKEGVIKIRSVASREEVAIKRENFVAEIQKRLSES
::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IPLVVIIGEQELKEGVIKIRSVASREEVAIKRENFVAEIQKRLSES
320 330 340 350 360
>>XP_016864781 (OMIM: 600783,614926) PREDICTED: probable (286 aa)
initn: 1861 init1: 1861 opt: 1861 Z-score: 2293.9 bits: 433.2 E(85289): 4.9e-121
Smith-Waterman score: 1861; 100.0% identity (100.0% similar) in 286 aa overlap (221-506:1-286)
200 210 220 230 240 250
pF1KE6 ECLKIMCEILSGLQLGDFLIKVNDRRIVDGMFAVCGVPESKFRAICSSIDKLDKMAWKDV
::::::::::::::::::::::::::::::
XP_016 MFAVCGVPESKFRAICSSIDKLDKMAWKDV
10 20 30
260 270 280 290 300 310
pF1KE6 RHEMVVKKGLAPEVADRIGDYVQCHGGVSLVEQMFQDPRLSQNKQALEGLGDLKLLFEYL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RHEMVVKKGLAPEVADRIGDYVQCHGGVSLVEQMFQDPRLSQNKQALEGLGDLKLLFEYL
40 50 60 70 80 90
320 330 340 350 360 370
pF1KE6 TLFGIADKISFDLSLARGLDYYTGVIYEAVLLQTPTQAGEEPLNVGSVAAGGRYDGLVGM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TLFGIADKISFDLSLARGLDYYTGVIYEAVLLQTPTQAGEEPLNVGSVAAGGRYDGLVGM
100 110 120 130 140 150
380 390 400 410 420 430
pF1KE6 FDPKGHKVPCVGLSIGVERIFYIVEQRMKTKGEKVRTTETQVFVATPQKNFLQERLKLIA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FDPKGHKVPCVGLSIGVERIFYIVEQRMKTKGEKVRTTETQVFVATPQKNFLQERLKLIA
160 170 180 190 200 210
440 450 460 470 480 490
pF1KE6 ELWDSGIKAEMLYKNNPKLLTQLHYCESTGIPLVVIIGEQELKEGVIKIRSVASREEVAI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ELWDSGIKAEMLYKNNPKLLTQLHYCESTGIPLVVIIGEQELKEGVIKIRSVASREEVAI
220 230 240 250 260 270
500
pF1KE6 KRENFVAEIQKRLSES
::::::::::::::::
XP_016 KRENFVAEIQKRLSES
280
506 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Nov 8 13:23:38 2016 done: Tue Nov 8 13:23:39 2016
Total Scan time: 7.370 Total Display time: 0.060
Function used was FASTA [36.3.4 Apr, 2011]