Result of FASTA (omim) for
pFN21AE6443
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE6443, 449 aa
1>>>pF1KE6443 449 - 449 aa - 449 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 8.0603+/-0.000315; mu= 5.5956+/- 0.020
mean_var=152.0895+/-30.781, 0's: 0 Z-trim(121.1): 222 B-trim: 0 in 0/58
Lambda= 0.103998
statistics sampled from 36949 (37188) to 36949 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.761), E-opt: 0.2 (0.436), width: 16
Scan time: 8.040
The best scores are: opt bits E(85289)
NP_002584 (OMIM: 600270) procollagen C-endopeptida ( 449) 3096 475.9 9.2e-134
NP_037495 (OMIM: 607064) procollagen C-endopeptida ( 415) 1034 166.5 1.2e-40
NP_001019800 (OMIM: 602069) neuropilin-1 isoform c ( 609) 546 93.4 1.8e-18
NP_001019799 (OMIM: 602069) neuropilin-1 isoform b ( 644) 546 93.4 1.8e-18
NP_001316997 (OMIM: 602069) neuropilin-1 isoform f ( 906) 546 93.5 2.5e-18
NP_001231902 (OMIM: 602069) neuropilin-1 isoform e ( 916) 546 93.5 2.5e-18
NP_001231901 (OMIM: 602069) neuropilin-1 isoform d ( 917) 546 93.5 2.5e-18
NP_003864 (OMIM: 602069) neuropilin-1 isoform a pr ( 923) 546 93.5 2.5e-18
XP_011518058 (OMIM: 602069) PREDICTED: neuropilin- ( 628) 541 92.7 3e-18
XP_011518057 (OMIM: 602069) PREDICTED: neuropilin- ( 656) 541 92.7 3.2e-18
XP_006717589 (OMIM: 602069) PREDICTED: neuropilin- ( 663) 541 92.7 3.2e-18
XP_006717588 (OMIM: 602069) PREDICTED: neuropilin- ( 888) 541 92.8 4.1e-18
XP_006717587 (OMIM: 602069) PREDICTED: neuropilin- ( 889) 541 92.8 4.1e-18
XP_016872354 (OMIM: 602069) PREDICTED: neuropilin- ( 899) 541 92.8 4.1e-18
XP_006717585 (OMIM: 602069) PREDICTED: neuropilin- ( 907) 541 92.8 4.1e-18
XP_006717584 (OMIM: 602069) PREDICTED: neuropilin- ( 924) 541 92.8 4.2e-18
NP_006120 (OMIM: 112264,614856) bone morphogenetic ( 986) 532 91.4 1.1e-17
XP_011530516 (OMIM: 606742,613087) PREDICTED: toll ( 837) 504 87.2 1.8e-16
XP_016864059 (OMIM: 606742,613087) PREDICTED: toll ( 964) 504 87.2 2e-16
NP_036596 (OMIM: 606742,613087) tolloid-like prote (1013) 504 87.2 2.1e-16
XP_011518012 (OMIM: 261100,602997) PREDICTED: cubi (2277) 506 87.7 3.4e-16
XP_011518011 (OMIM: 261100,602997) PREDICTED: cubi (2285) 506 87.7 3.4e-16
XP_011518013 (OMIM: 261100,602997) PREDICTED: cubi (2237) 501 87.0 5.7e-16
NP_071317 (OMIM: 616644) CUB and zona pellucida-li ( 607) 401 71.7 6.2e-12
XP_011518010 (OMIM: 261100,602997) PREDICTED: cubi (2867) 343 63.3 9.5e-09
NP_001072 (OMIM: 261100,602997) cubilin precursor (3623) 343 63.4 1.2e-08
NP_957716 (OMIM: 602070) neuropilin-2 isoform 6 pr ( 555) 308 57.7 9.2e-08
XP_016860677 (OMIM: 602070) PREDICTED: neuropilin- ( 848) 308 57.8 1.3e-07
XP_016860676 (OMIM: 602070) PREDICTED: neuropilin- ( 853) 308 57.8 1.3e-07
NP_957719 (OMIM: 602070) neuropilin-2 isoform 5 pr ( 901) 308 57.8 1.4e-07
XP_016860675 (OMIM: 602070) PREDICTED: neuropilin- ( 901) 308 57.8 1.4e-07
NP_061004 (OMIM: 602070) neuropilin-2 isoform 4 pr ( 906) 308 57.8 1.4e-07
NP_958436 (OMIM: 602070) neuropilin-2 isoform 3 pr ( 909) 308 57.8 1.4e-07
XP_016860674 (OMIM: 602070) PREDICTED: neuropilin- ( 926) 308 57.8 1.4e-07
NP_003863 (OMIM: 602070) neuropilin-2 isoform 2 pr ( 926) 308 57.8 1.4e-07
NP_957718 (OMIM: 602070) neuropilin-2 isoform 1 pr ( 931) 308 57.8 1.4e-07
XP_005246990 (OMIM: 602070) PREDICTED: neuropilin- ( 931) 308 57.8 1.4e-07
XP_005246991 (OMIM: 602070) PREDICTED: neuropilin- ( 931) 308 57.8 1.4e-07
XP_011542919 (OMIM: 112264,614856) PREDICTED: bone ( 622) 304 57.1 1.5e-07
XP_016869227 (OMIM: 112264,614856) PREDICTED: bone ( 717) 304 57.1 1.7e-07
NP_001190 (OMIM: 112264,614856) bone morphogenetic ( 730) 304 57.2 1.7e-07
XP_006716449 (OMIM: 112264,614856) PREDICTED: bone ( 813) 304 57.2 1.9e-07
NP_036597 (OMIM: 606743) tolloid-like protein 2 pr (1015) 301 56.8 3.1e-07
NP_963840 (OMIM: 612320) CUB domain-containing pro ( 449) 294 55.5 3.3e-07
NP_113621 (OMIM: 606227,609549,611040) membrane fr ( 579) 296 55.9 3.3e-07
XP_016881511 (OMIM: 607973) PREDICTED: neuropilin ( 236) 280 53.3 8.2e-07
XP_011537717 (OMIM: 601969) PREDICTED: deleted in (1766) 290 55.3 1.6e-06
XP_011537716 (OMIM: 601969) PREDICTED: deleted in (1783) 290 55.3 1.6e-06
NP_004397 (OMIM: 601969) deleted in malignant brai (1785) 290 55.3 1.6e-06
XP_016871287 (OMIM: 601969) PREDICTED: deleted in (1990) 290 55.3 1.7e-06
>>NP_002584 (OMIM: 600270) procollagen C-endopeptidase e (449 aa)
initn: 3096 init1: 3096 opt: 3096 Z-score: 2522.5 bits: 475.9 E(85289): 9.2e-134
Smith-Waterman score: 3096; 100.0% identity (100.0% similar) in 449 aa overlap (1-449:1-449)
10 20 30 40 50 60
pF1KE6 MLPAATASLLGPLLTACALLPFAQGQTPNYTRPVFLCGGDVKGESGYVASEGFPNLYPPN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 MLPAATASLLGPLLTACALLPFAQGQTPNYTRPVFLCGGDVKGESGYVASEGFPNLYPPN
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 KECIWTITVPEGQTVSLSFRVFDLELHPACRYDALEVFAGSGTSGQRLGRFCGTFRPAPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 KECIWTITVPEGQTVSLSFRVFDLELHPACRYDALEVFAGSGTSGQRLGRFCGTFRPAPL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 VAPGNQVTLRMTTDEGTGGRGFLLWYSGRATSGTEHQFCGGRLEKAQGTLTTPNWPESDY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 VAPGNQVTLRMTTDEGTGGRGFLLWYSGRATSGTEHQFCGGRLEKAQGTLTTPNWPESDY
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE6 PPGISCSWHIIAPPDQVIALTFEKFDLEPDTYCRYDSVSVFNGAVSDDSRRLGKFCGDAV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 PPGISCSWHIIAPPDQVIALTFEKFDLEPDTYCRYDSVSVFNGAVSDDSRRLGKFCGDAV
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE6 PGSISSEGNELLVQFVSDLSVTADGFSASYKTLPRGTAKEGQGPGPKRGTEPKVKLPPKS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 PGSISSEGNELLVQFVSDLSVTADGFSASYKTLPRGTAKEGQGPGPKRGTEPKVKLPPKS
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE6 QPPEKTEESPSAPDAPTCPKQCRRTGTLQSNFCASSLVVTATVKSMVREPGEGLAVTVSL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 QPPEKTEESPSAPDAPTCPKQCRRTGTLQSNFCASSLVVTATVKSMVREPGEGLAVTVSL
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE6 IGAYKTGGLDLPSPPTGASLKFYVPCKQCPPMKKGVSYLLMGQVEENRGPVLPPESFVVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 IGAYKTGGLDLPSPPTGASLKFYVPCKQCPPMKKGVSYLLMGQVEENRGPVLPPESFVVL
370 380 390 400 410 420
430 440
pF1KE6 HRPNQDQILTNLSKRKCPSQPVRAAASQD
:::::::::::::::::::::::::::::
NP_002 HRPNQDQILTNLSKRKCPSQPVRAAASQD
430 440
>>NP_037495 (OMIM: 607064) procollagen C-endopeptidase e (415 aa)
initn: 1324 init1: 711 opt: 1034 Z-score: 851.0 bits: 166.5 E(85289): 1.2e-40
Smith-Waterman score: 1328; 44.5% identity (71.6% similar) in 436 aa overlap (7-437:4-415)
10 20 30 40 50
pF1KE6 MLPAATASLLGPL-LTACALLPFAQGQTPNYTRPVFLCGGDVKGESGYVASEGFPNLYPP
:. .:: : : ... :.:. :::: ::: . ::::...:::::..:::
NP_037 MRGANAWAPLCLLLAAATQLSRQQSPE--RPVFTCGGILTGESGFIGSEGFPGVYPP
10 20 30 40 50
60 70 80 90 100 110
pF1KE6 NKECIWTITVPEGQTVSLSFRVFDLELHPACRYDALEVFAGSGTSGQRLGRFCGTFRPAP
:..: : ::::::..: :.:: .::: :::: ..:. : . .:::.:::::::::.
NP_037 NSKCTWKITVPEGKVVVLNFRFIDLESDNLCRYDFVDVYNGHA-NGQRIGRFCGTFRPGA
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE6 LVAPGNQVTLRMTTDEGTGGRGFLLWYSGRATSGTEHQFCGGRLEKAQGTLTTPNWPESD
::. ::.. ..: .: .:.: ::. .:. . :.::: :.. .:.. :::::. :
NP_037 LVSSGNKMMVQMISDANTAGNGFMAMFSAAEPNERGDQYCGGLLDRPSGSFKTPNWPDRD
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE6 YPPGISCSWHIIAPPDQVIALTFEKFDLEPDTYCRYDSVSVFNGAVSDDSRRLGKFCGDA
:: :..: :::.:: .:.: : :::::.: :.::::: :.::::. .:.::.::.:::.
NP_037 YPAGVTCVWHIVAPKNQLIELKFEKFDVERDNYCRYDYVAVFNGGEVNDARRIGKYCGDS
180 190 200 210 220 230
240 250 260 270 280 290
pF1KE6 VPGSISSEGNELLVQFVSDLSVTADGFSASYKTLPRGTAKEGQGPGPKRGTEPKVKLPPK
:. : :: ::::.::.::::.::::: . : :. :::
NP_037 PPAPIVSERNELLIQFLSDLSLTADGFIGHYIFRPK-------------------KLPTT
240 250 260 270
300 310 320 330 340 350
pF1KE6 SQPPEKTEESPSAPDAPT---CPKQCRRTGTLQSNFCASSLVVTATVKSMVREPGEGLAV
.. : : .. :: : ..:::::::..:.:.:..:...:: . . . : .: .
NP_037 TEQPVTTTFPVTTGLKPTVALCQQKCRRTGTLEGNYCSSDFVLAGTVITTITRDG-SLHA
280 290 300 310 320 330
360 370 380 390 400 410
pF1KE6 TVSLIGAYKTGGLDLPSPPTGASLKFYVPCKQCPPMKKGVSYLLMGQV-EENRGPVLPPE
:::.:. :: :.: . . . : .. : ::::: ...:..:..:::: :..:: ..: .
NP_037 TVSIINIYKEGNLAIQQAGKNMSARLTVVCKQCPLLRRGLNYIIMGQVGEDGRGKIMP-N
340 350 360 370 380 390
420 430 440
pF1KE6 SFVVLHRPNQDQILTNLSKRKCPSQPVRAAASQD
::... . .....: :....:
NP_037 SFIMMFKTKNQKLLDALKNKQC
400 410
>>NP_001019800 (OMIM: 602069) neuropilin-1 isoform c pre (609 aa)
initn: 313 init1: 188 opt: 546 Z-score: 452.8 bits: 93.4 E(85289): 1.8e-18
Smith-Waterman score: 546; 33.8% identity (62.9% similar) in 278 aa overlap (12-280:6-272)
10 20 30 40 50
pF1KE6 MLPAATASLLGPLLTACALLPFAQGQTPNYTRPVFLCGGDVKGES-GYVASEGFPNLYPP
::: ::.: .. . . . :: .: :: ::..: :.:. : :
NP_001 MERGLPLL--CAVLALVLAPAGAFRND--KCGDTIKIESPGYLTSPGYPHSYHP
10 20 30 40 50
60 70 80 90 100 110
pF1KE6 NKECIWTITVPEG-QTVSLSFRV-FDLELHPACRYDALEVFAGSGTSGQRLGRFCGTFRP
...: : : .:. : . ..: :::: . :.:: .::: : . .:. :.::: . :
NP_001 SEKCEWLIQAPDPYQRIMINFNPHFDLEDRD-CKYDYVEVFDGENENGHFRGKFCGKIAP
60 70 80 90 100
120 130 140 150 160 170
pF1KE6 APLVAPGNQVTLRMTTDEGTGGRGFLLWYSGRATSGTEHQFCGGRLEKAQGTLTTPNWPE
:.:. : . .....: : : :: . : : : :. .:.. .:..::
NP_001 PPVVSSGPFLFIKFVSDYETHGAGFSIRYEIFKR-GPE---CSQNYTTPSGVIKSPGFPE
110 120 130 140 150 160
180 190 200 210 220 230
pF1KE6 SDYPPGISCSWHIIAPPDQVIALTFEKFDLEPDT------YCRYDSVSVFNGAVSDDSRR
. :: .. :.. ..:: . : : ::.::::::. .:::: . ...: : . .
NP_001 K-YPNSLECTYIVFAPKMSEIILEFESFDLEPDSNPPGGMFCRYDRLEIWDG-FPDVGPH
170 180 190 200 210 220
240 250 260 270 280 290
pF1KE6 LGKFCGDAVPGSISSEGNELLVQFVSDLSVTADGFSASYKTLPRGTAKEGQGPGPKRGTE
.:..::. .:: : : .. : . : .: ... .::::.:..: .....
NP_001 IGRYCGQKTPGRIRSSSGILSMVFYTDSAIAKEGFSANYSVLQSSVSEDFKCMEALGMES
230 240 250 260 270 280
300 310 320 330 340 350
pF1KE6 PKVKLPPKSQPPEKTEESPSAPDAPTCPKQCRRTGTLQSNFCASSLVVTATVKSMVREPG
NP_001 GEIHSDQITASSQYSTNWSAERSRLNYPENGWTPGEDSYREWIQVDLGLLRFVTAVGTQG
290 300 310 320 330 340
>>NP_001019799 (OMIM: 602069) neuropilin-1 isoform b pre (644 aa)
initn: 313 init1: 188 opt: 546 Z-score: 452.4 bits: 93.4 E(85289): 1.8e-18
Smith-Waterman score: 546; 33.8% identity (62.9% similar) in 278 aa overlap (12-280:6-272)
10 20 30 40 50
pF1KE6 MLPAATASLLGPLLTACALLPFAQGQTPNYTRPVFLCGGDVKGES-GYVASEGFPNLYPP
::: ::.: .. . . . :: .: :: ::..: :.:. : :
NP_001 MERGLPLL--CAVLALVLAPAGAFRND--KCGDTIKIESPGYLTSPGYPHSYHP
10 20 30 40 50
60 70 80 90 100 110
pF1KE6 NKECIWTITVPEG-QTVSLSFRV-FDLELHPACRYDALEVFAGSGTSGQRLGRFCGTFRP
...: : : .:. : . ..: :::: . :.:: .::: : . .:. :.::: . :
NP_001 SEKCEWLIQAPDPYQRIMINFNPHFDLEDRD-CKYDYVEVFDGENENGHFRGKFCGKIAP
60 70 80 90 100
120 130 140 150 160 170
pF1KE6 APLVAPGNQVTLRMTTDEGTGGRGFLLWYSGRATSGTEHQFCGGRLEKAQGTLTTPNWPE
:.:. : . .....: : : :: . : : : :. .:.. .:..::
NP_001 PPVVSSGPFLFIKFVSDYETHGAGFSIRYEIFKR-GPE---CSQNYTTPSGVIKSPGFPE
110 120 130 140 150 160
180 190 200 210 220 230
pF1KE6 SDYPPGISCSWHIIAPPDQVIALTFEKFDLEPDT------YCRYDSVSVFNGAVSDDSRR
. :: .. :.. ..:: . : : ::.::::::. .:::: . ...: : . .
NP_001 K-YPNSLECTYIVFAPKMSEIILEFESFDLEPDSNPPGGMFCRYDRLEIWDG-FPDVGPH
170 180 190 200 210 220
240 250 260 270 280 290
pF1KE6 LGKFCGDAVPGSISSEGNELLVQFVSDLSVTADGFSASYKTLPRGTAKEGQGPGPKRGTE
.:..::. .:: : : .. : . : .: ... .::::.:..: .....
NP_001 IGRYCGQKTPGRIRSSSGILSMVFYTDSAIAKEGFSANYSVLQSSVSEDFKCMEALGMES
230 240 250 260 270 280
300 310 320 330 340 350
pF1KE6 PKVKLPPKSQPPEKTEESPSAPDAPTCPKQCRRTGTLQSNFCASSLVVTATVKSMVREPG
NP_001 GEIHSDQITASSQYSTNWSAERSRLNYPENGWTPGEDSYREWIQVDLGLLRFVTAVGTQG
290 300 310 320 330 340
>>NP_001316997 (OMIM: 602069) neuropilin-1 isoform f pre (906 aa)
initn: 313 init1: 188 opt: 546 Z-score: 450.2 bits: 93.5 E(85289): 2.5e-18
Smith-Waterman score: 546; 33.8% identity (62.9% similar) in 278 aa overlap (12-280:6-272)
10 20 30 40 50
pF1KE6 MLPAATASLLGPLLTACALLPFAQGQTPNYTRPVFLCGGDVKGES-GYVASEGFPNLYPP
::: ::.: .. . . . :: .: :: ::..: :.:. : :
NP_001 MERGLPLL--CAVLALVLAPAGAFRND--KCGDTIKIESPGYLTSPGYPHSYHP
10 20 30 40 50
60 70 80 90 100 110
pF1KE6 NKECIWTITVPEG-QTVSLSFRV-FDLELHPACRYDALEVFAGSGTSGQRLGRFCGTFRP
...: : : .:. : . ..: :::: . :.:: .::: : . .:. :.::: . :
NP_001 SEKCEWLIQAPDPYQRIMINFNPHFDLEDRD-CKYDYVEVFDGENENGHFRGKFCGKIAP
60 70 80 90 100
120 130 140 150 160 170
pF1KE6 APLVAPGNQVTLRMTTDEGTGGRGFLLWYSGRATSGTEHQFCGGRLEKAQGTLTTPNWPE
:.:. : . .....: : : :: . : : : :. .:.. .:..::
NP_001 PPVVSSGPFLFIKFVSDYETHGAGFSIRYEIFKR-GPE---CSQNYTTPSGVIKSPGFPE
110 120 130 140 150 160
180 190 200 210 220 230
pF1KE6 SDYPPGISCSWHIIAPPDQVIALTFEKFDLEPDT------YCRYDSVSVFNGAVSDDSRR
. :: .. :.. ..:: . : : ::.::::::. .:::: . ...: : . .
NP_001 K-YPNSLECTYIVFAPKMSEIILEFESFDLEPDSNPPGGMFCRYDRLEIWDG-FPDVGPH
170 180 190 200 210 220
240 250 260 270 280 290
pF1KE6 LGKFCGDAVPGSISSEGNELLVQFVSDLSVTADGFSASYKTLPRGTAKEGQGPGPKRGTE
.:..::. .:: : : .. : . : .: ... .::::.:..: .....
NP_001 IGRYCGQKTPGRIRSSSGILSMVFYTDSAIAKEGFSANYSVLQSSVSEDFKCMEALGMES
230 240 250 260 270 280
300 310 320 330 340 350
pF1KE6 PKVKLPPKSQPPEKTEESPSAPDAPTCPKQCRRTGTLQSNFCASSLVVTATVKSMVREPG
NP_001 GEIHSDQITASSQYSTNWSAERSRLNYPENGWTPGEDSYREWIQVDLGLLRFVTAVGTQG
290 300 310 320 330 340
>>NP_001231902 (OMIM: 602069) neuropilin-1 isoform e pre (916 aa)
initn: 313 init1: 188 opt: 546 Z-score: 450.1 bits: 93.5 E(85289): 2.5e-18
Smith-Waterman score: 546; 33.8% identity (62.9% similar) in 278 aa overlap (12-280:6-272)
10 20 30 40 50
pF1KE6 MLPAATASLLGPLLTACALLPFAQGQTPNYTRPVFLCGGDVKGES-GYVASEGFPNLYPP
::: ::.: .. . . . :: .: :: ::..: :.:. : :
NP_001 MERGLPLL--CAVLALVLAPAGAFRND--KCGDTIKIESPGYLTSPGYPHSYHP
10 20 30 40 50
60 70 80 90 100 110
pF1KE6 NKECIWTITVPEG-QTVSLSFRV-FDLELHPACRYDALEVFAGSGTSGQRLGRFCGTFRP
...: : : .:. : . ..: :::: . :.:: .::: : . .:. :.::: . :
NP_001 SEKCEWLIQAPDPYQRIMINFNPHFDLEDRD-CKYDYVEVFDGENENGHFRGKFCGKIAP
60 70 80 90 100
120 130 140 150 160 170
pF1KE6 APLVAPGNQVTLRMTTDEGTGGRGFLLWYSGRATSGTEHQFCGGRLEKAQGTLTTPNWPE
:.:. : . .....: : : :: . : : : :. .:.. .:..::
NP_001 PPVVSSGPFLFIKFVSDYETHGAGFSIRYEIFKR-GPE---CSQNYTTPSGVIKSPGFPE
110 120 130 140 150 160
180 190 200 210 220 230
pF1KE6 SDYPPGISCSWHIIAPPDQVIALTFEKFDLEPDT------YCRYDSVSVFNGAVSDDSRR
. :: .. :.. ..:: . : : ::.::::::. .:::: . ...: : . .
NP_001 K-YPNSLECTYIVFAPKMSEIILEFESFDLEPDSNPPGGMFCRYDRLEIWDG-FPDVGPH
170 180 190 200 210 220
240 250 260 270 280 290
pF1KE6 LGKFCGDAVPGSISSEGNELLVQFVSDLSVTADGFSASYKTLPRGTAKEGQGPGPKRGTE
.:..::. .:: : : .. : . : .: ... .::::.:..: .....
NP_001 IGRYCGQKTPGRIRSSSGILSMVFYTDSAIAKEGFSANYSVLQSSVSEDFKCMEALGMES
230 240 250 260 270 280
300 310 320 330 340 350
pF1KE6 PKVKLPPKSQPPEKTEESPSAPDAPTCPKQCRRTGTLQSNFCASSLVVTATVKSMVREPG
NP_001 GEIHSDQITASSQYSTNWSAERSRLNYPENGWTPGEDSYREWIQVDLGLLRFVTAVGTQG
290 300 310 320 330 340
>>NP_001231901 (OMIM: 602069) neuropilin-1 isoform d pre (917 aa)
initn: 313 init1: 188 opt: 546 Z-score: 450.1 bits: 93.5 E(85289): 2.5e-18
Smith-Waterman score: 546; 33.8% identity (62.9% similar) in 278 aa overlap (12-280:6-272)
10 20 30 40 50
pF1KE6 MLPAATASLLGPLLTACALLPFAQGQTPNYTRPVFLCGGDVKGES-GYVASEGFPNLYPP
::: ::.: .. . . . :: .: :: ::..: :.:. : :
NP_001 MERGLPLL--CAVLALVLAPAGAFRND--KCGDTIKIESPGYLTSPGYPHSYHP
10 20 30 40 50
60 70 80 90 100 110
pF1KE6 NKECIWTITVPEG-QTVSLSFRV-FDLELHPACRYDALEVFAGSGTSGQRLGRFCGTFRP
...: : : .:. : . ..: :::: . :.:: .::: : . .:. :.::: . :
NP_001 SEKCEWLIQAPDPYQRIMINFNPHFDLEDRD-CKYDYVEVFDGENENGHFRGKFCGKIAP
60 70 80 90 100
120 130 140 150 160 170
pF1KE6 APLVAPGNQVTLRMTTDEGTGGRGFLLWYSGRATSGTEHQFCGGRLEKAQGTLTTPNWPE
:.:. : . .....: : : :: . : : : :. .:.. .:..::
NP_001 PPVVSSGPFLFIKFVSDYETHGAGFSIRYEIFKR-GPE---CSQNYTTPSGVIKSPGFPE
110 120 130 140 150 160
180 190 200 210 220 230
pF1KE6 SDYPPGISCSWHIIAPPDQVIALTFEKFDLEPDT------YCRYDSVSVFNGAVSDDSRR
. :: .. :.. ..:: . : : ::.::::::. .:::: . ...: : . .
NP_001 K-YPNSLECTYIVFAPKMSEIILEFESFDLEPDSNPPGGMFCRYDRLEIWDG-FPDVGPH
170 180 190 200 210 220
240 250 260 270 280 290
pF1KE6 LGKFCGDAVPGSISSEGNELLVQFVSDLSVTADGFSASYKTLPRGTAKEGQGPGPKRGTE
.:..::. .:: : : .. : . : .: ... .::::.:..: .....
NP_001 IGRYCGQKTPGRIRSSSGILSMVFYTDSAIAKEGFSANYSVLQSSVSEDFKCMEALGMES
230 240 250 260 270 280
300 310 320 330 340 350
pF1KE6 PKVKLPPKSQPPEKTEESPSAPDAPTCPKQCRRTGTLQSNFCASSLVVTATVKSMVREPG
NP_001 GEIHSDQITASSQYSTNWSAERSRLNYPENGWTPGEDSYREWIQVDLGLLRFVTAVGTQG
290 300 310 320 330 340
>>NP_003864 (OMIM: 602069) neuropilin-1 isoform a precur (923 aa)
initn: 313 init1: 188 opt: 546 Z-score: 450.0 bits: 93.5 E(85289): 2.5e-18
Smith-Waterman score: 546; 33.8% identity (62.9% similar) in 278 aa overlap (12-280:6-272)
10 20 30 40 50
pF1KE6 MLPAATASLLGPLLTACALLPFAQGQTPNYTRPVFLCGGDVKGES-GYVASEGFPNLYPP
::: ::.: .. . . . :: .: :: ::..: :.:. : :
NP_003 MERGLPLL--CAVLALVLAPAGAFRND--KCGDTIKIESPGYLTSPGYPHSYHP
10 20 30 40 50
60 70 80 90 100 110
pF1KE6 NKECIWTITVPEG-QTVSLSFRV-FDLELHPACRYDALEVFAGSGTSGQRLGRFCGTFRP
...: : : .:. : . ..: :::: . :.:: .::: : . .:. :.::: . :
NP_003 SEKCEWLIQAPDPYQRIMINFNPHFDLEDRD-CKYDYVEVFDGENENGHFRGKFCGKIAP
60 70 80 90 100
120 130 140 150 160 170
pF1KE6 APLVAPGNQVTLRMTTDEGTGGRGFLLWYSGRATSGTEHQFCGGRLEKAQGTLTTPNWPE
:.:. : . .....: : : :: . : : : :. .:.. .:..::
NP_003 PPVVSSGPFLFIKFVSDYETHGAGFSIRYEIFKR-GPE---CSQNYTTPSGVIKSPGFPE
110 120 130 140 150 160
180 190 200 210 220 230
pF1KE6 SDYPPGISCSWHIIAPPDQVIALTFEKFDLEPDT------YCRYDSVSVFNGAVSDDSRR
. :: .. :.. ..:: . : : ::.::::::. .:::: . ...: : . .
NP_003 K-YPNSLECTYIVFAPKMSEIILEFESFDLEPDSNPPGGMFCRYDRLEIWDG-FPDVGPH
170 180 190 200 210 220
240 250 260 270 280 290
pF1KE6 LGKFCGDAVPGSISSEGNELLVQFVSDLSVTADGFSASYKTLPRGTAKEGQGPGPKRGTE
.:..::. .:: : : .. : . : .: ... .::::.:..: .....
NP_003 IGRYCGQKTPGRIRSSSGILSMVFYTDSAIAKEGFSANYSVLQSSVSEDFKCMEALGMES
230 240 250 260 270 280
300 310 320 330 340 350
pF1KE6 PKVKLPPKSQPPEKTEESPSAPDAPTCPKQCRRTGTLQSNFCASSLVVTATVKSMVREPG
NP_003 GEIHSDQITASSQYSTNWSAERSRLNYPENGWTPGEDSYREWIQVDLGLLRFVTAVGTQG
290 300 310 320 330 340
>>XP_011518058 (OMIM: 602069) PREDICTED: neuropilin-1 is (628 aa)
initn: 310 init1: 185 opt: 541 Z-score: 448.5 bits: 92.7 E(85289): 3e-18
Smith-Waterman score: 541; 33.5% identity (62.9% similar) in 278 aa overlap (12-280:6-272)
10 20 30 40 50
pF1KE6 MLPAATASLLGPLLTACALLPFAQGQTPNYTRPVFLCGGDVKGES-GYVASEGFPNLYPP
::: ::.: .. . . . :: .: :: ::..: :.:. : :
XP_011 MERGLPLL--CAVLALVLAPAGAFRND--KCGDTIKIESPGYLTSPGYPHSYHP
10 20 30 40 50
60 70 80 90 100 110
pF1KE6 NKECIWTITVPEG-QTVSLSFRV-FDLELHPACRYDALEVFAGSGTSGQRLGRFCGTFRP
...: : : .:. : . ..: :::: . :.:: .::: : . .:. :.::: . :
XP_011 SEKCEWLIQAPDPYQRIMINFNPHFDLEDRD-CKYDYVEVFDGENENGHFRGKFCGKIAP
60 70 80 90 100
120 130 140 150 160 170
pF1KE6 APLVAPGNQVTLRMTTDEGTGGRGFLLWYSGRATSGTEHQFCGGRLEKAQGTLTTPNWPE
:.:. : . .....: : : :: . : : : :. .:.. .:..::
XP_011 PPVVSSGPFLFIKFVSDYETHGAGFSIRYEIFKR-GPE---CSQNYTTPSGVIKSPGFPE
110 120 130 140 150 160
180 190 200 210 220 230
pF1KE6 SDYPPGISCSWHIIAPPDQVIALTFEKFDLEPDT------YCRYDSVSVFNGAVSDDSRR
. :: .. :.. ...: . : : ::.::::::. .:::: . ...: : . .
XP_011 K-YPNSLECTYIVFVPKMSEIILEFESFDLEPDSNPPGGMFCRYDRLEIWDG-FPDVGPH
170 180 190 200 210 220
240 250 260 270 280 290
pF1KE6 LGKFCGDAVPGSISSEGNELLVQFVSDLSVTADGFSASYKTLPRGTAKEGQGPGPKRGTE
.:..::. .:: : : .. : . : .: ... .::::.:..: .....
XP_011 IGRYCGQKTPGRIRSSSGILSMVFYTDSAIAKEGFSANYSVLQSSVSEDFKCMEALGMES
230 240 250 260 270 280
300 310 320 330 340 350
pF1KE6 PKVKLPPKSQPPEKTEESPSAPDAPTCPKQCRRTGTLQSNFCASSLVVTATVKSMVREPG
XP_011 GEIHSDQITASSQYSTNWSAERSRLNYPENGWTPGEDSYREWIQVDLGLLRFVTAVGTQG
290 300 310 320 330 340
>>XP_011518057 (OMIM: 602069) PREDICTED: neuropilin-1 is (656 aa)
initn: 310 init1: 185 opt: 541 Z-score: 448.2 bits: 92.7 E(85289): 3.2e-18
Smith-Waterman score: 541; 33.5% identity (62.9% similar) in 278 aa overlap (12-280:6-272)
10 20 30 40 50
pF1KE6 MLPAATASLLGPLLTACALLPFAQGQTPNYTRPVFLCGGDVKGES-GYVASEGFPNLYPP
::: ::.: .. . . . :: .: :: ::..: :.:. : :
XP_011 MERGLPLL--CAVLALVLAPAGAFRND--KCGDTIKIESPGYLTSPGYPHSYHP
10 20 30 40 50
60 70 80 90 100 110
pF1KE6 NKECIWTITVPEG-QTVSLSFRV-FDLELHPACRYDALEVFAGSGTSGQRLGRFCGTFRP
...: : : .:. : . ..: :::: . :.:: .::: : . .:. :.::: . :
XP_011 SEKCEWLIQAPDPYQRIMINFNPHFDLEDRD-CKYDYVEVFDGENENGHFRGKFCGKIAP
60 70 80 90 100
120 130 140 150 160 170
pF1KE6 APLVAPGNQVTLRMTTDEGTGGRGFLLWYSGRATSGTEHQFCGGRLEKAQGTLTTPNWPE
:.:. : . .....: : : :: . : : : :. .:.. .:..::
XP_011 PPVVSSGPFLFIKFVSDYETHGAGFSIRYEIFKR-GPE---CSQNYTTPSGVIKSPGFPE
110 120 130 140 150 160
180 190 200 210 220 230
pF1KE6 SDYPPGISCSWHIIAPPDQVIALTFEKFDLEPDT------YCRYDSVSVFNGAVSDDSRR
. :: .. :.. ...: . : : ::.::::::. .:::: . ...: : . .
XP_011 K-YPNSLECTYIVFVPKMSEIILEFESFDLEPDSNPPGGMFCRYDRLEIWDG-FPDVGPH
170 180 190 200 210 220
240 250 260 270 280 290
pF1KE6 LGKFCGDAVPGSISSEGNELLVQFVSDLSVTADGFSASYKTLPRGTAKEGQGPGPKRGTE
.:..::. .:: : : .. : . : .: ... .::::.:..: .....
XP_011 IGRYCGQKTPGRIRSSSGILSMVFYTDSAIAKEGFSANYSVLQSSVSEDFKCMEALGMES
230 240 250 260 270 280
300 310 320 330 340 350
pF1KE6 PKVKLPPKSQPPEKTEESPSAPDAPTCPKQCRRTGTLQSNFCASSLVVTATVKSMVREPG
XP_011 GEIHSDQITASSQYSTNWSAERSRLNYPENGWTPGEDSYREWIQVDLGLLRFVTAVGTQG
290 300 310 320 330 340
449 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Nov 8 13:21:13 2016 done: Tue Nov 8 13:21:14 2016
Total Scan time: 8.040 Total Display time: 0.030
Function used was FASTA [36.3.4 Apr, 2011]