Result of FASTA (omim) for
pFN21AE6442
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE6442, 455 aa
1>>>pF1KE6442 455 - 455 aa - 455 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 4.4239+/-0.000333; mu= 23.5119+/- 0.021
mean_var=77.4633+/-16.185, 0's: 0 Z-trim(116.5): 91 B-trim: 1036 in 1/48
Lambda= 0.145722
statistics sampled from 27533 (27646) to 27533 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.673), E-opt: 0.2 (0.324), width: 16
Scan time: 8.530
The best scores are: opt bits E(85289)
NP_001139541 (OMIM: 610977) major facilitator supe ( 455) 3009 642.1 9.2e-184
NP_001111 (OMIM: 610977) major facilitator superfa ( 455) 3009 642.1 9.2e-184
XP_005247984 (OMIM: 610977) PREDICTED: major facil ( 480) 2749 587.4 2.7e-167
NP_002546 (OMIM: 114480,211980,268210,602631) solu ( 424) 237 59.3 2.4e-08
NP_899056 (OMIM: 114480,211980,268210,602631) solu ( 424) 237 59.3 2.4e-08
NP_001302430 (OMIM: 114480,211980,268210,602631) s ( 509) 237 59.4 2.7e-08
XP_005262954 (OMIM: 610951,611124,616170) PREDICTE ( 451) 190 49.4 2.3e-05
XP_011518443 (OMIM: 114480,211980,268210,602631) P ( 386) 173 45.8 0.00025
XP_011518444 (OMIM: 114480,211980,268210,602631) P ( 379) 167 44.5 0.00059
NP_001258640 (OMIM: 605245) solute carrier family ( 411) 165 44.1 0.00084
XP_006717147 (OMIM: 605245) PREDICTED: solute carr ( 437) 165 44.2 0.00087
NP_055395 (OMIM: 605245) solute carrier family 2, ( 477) 165 44.2 0.00092
NP_001273050 (OMIM: 604216) probable small intesti ( 443) 161 43.3 0.0016
XP_011512513 (OMIM: 604216) PREDICTED: probable sm ( 443) 161 43.3 0.0016
XP_011516904 (OMIM: 605245) PREDICTED: solute carr ( 451) 161 43.3 0.0016
NP_005486 (OMIM: 604216) probable small intestine ( 497) 161 43.4 0.0017
NP_775857 (OMIM: 611698) solute carrier family 22 ( 322) 157 42.3 0.0023
XP_006715615 (OMIM: 602607) PREDICTED: solute carr ( 483) 153 41.7 0.0053
NP_694857 (OMIM: 602607) solute carrier family 22 ( 506) 153 41.7 0.0055
NP_001129978 (OMIM: 611698) solute carrier family ( 552) 153 41.7 0.0058
NP_003048 (OMIM: 602607) solute carrier family 22 ( 554) 153 41.7 0.0058
XP_005267160 (OMIM: 602607) PREDICTED: solute carr ( 573) 153 41.8 0.0059
XP_005267159 (OMIM: 602607) PREDICTED: solute carr ( 610) 153 41.8 0.0062
XP_016863478 (OMIM: 610951,611124,616170) PREDICTE ( 269) 149 40.5 0.0065
>>NP_001139541 (OMIM: 610977) major facilitator superfam (455 aa)
initn: 3009 init1: 3009 opt: 3009 Z-score: 3420.1 bits: 642.1 E(85289): 9.2e-184
Smith-Waterman score: 3009; 100.0% identity (100.0% similar) in 455 aa overlap (1-455:1-455)
10 20 30 40 50 60
pF1KE6 MGWGGGGGCTPRPPIHQQPPERRVVTVVFLGLLLDLLAFTLLLPLLPGLLESHGRAHDPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MGWGGGGGCTPRPPIHQQPPERRVVTVVFLGLLLDLLAFTLLLPLLPGLLESHGRAHDPL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 YGSWQGGVDWFATAIGMPVEKRYNSVLFGGLIGSAFSVLQFLCAPLTGATSDCLGRRPVM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YGSWQGGVDWFATAIGMPVEKRYNSVLFGGLIGSAFSVLQFLCAPLTGATSDCLGRRPVM
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 LLCLMGVATSYAVWATSRSFAAFLASRLIGGISKGNVSLSTAIVADLGSPLARSQGMAVI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LLCLMGVATSYAVWATSRSFAAFLASRLIGGISKGNVSLSTAIVADLGSPLARSQGMAVI
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE6 GVAFSLGFTLGPMLGASLPLEMAPWFALLFAASDLLFIFCFLPETLPLEKRAPSIALGFR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GVAFSLGFTLGPMLGASLPLEMAPWFALLFAASDLLFIFCFLPETLPLEKRAPSIALGFR
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE6 DAADLLSPLALLRFSAVARGQDPPSGDRLSSLRRLGLVYFLYLFLFSGLEYTLSFLTHQR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DAADLLSPLALLRFSAVARGQDPPSGDRLSSLRRLGLVYFLYLFLFSGLEYTLSFLTHQR
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE6 FQFSSLQQGKMFFLIGLTMATIQGAYARRIHPGGEVAAVKRALLLLVPAFLLIGWGRSLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FQFSSLQQGKMFFLIGLTMATIQGAYARRIHPGGEVAAVKRALLLLVPAFLLIGWGRSLP
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE6 VLGLGLLLYSFAAAVVVPCLSSVVAGYGSPGQKGTVMGTLRSLGALARAAGPLVAASVYW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VLGLGLLLYSFAAAVVVPCLSSVVAGYGSPGQKGTVMGTLRSLGALARAAGPLVAASVYW
370 380 390 400 410 420
430 440 450
pF1KE6 LAGAQACFTTWSGLFLLPFFLLQKLSYPAQTLKAE
:::::::::::::::::::::::::::::::::::
NP_001 LAGAQACFTTWSGLFLLPFFLLQKLSYPAQTLKAE
430 440 450
>>NP_001111 (OMIM: 610977) major facilitator superfamily (455 aa)
initn: 3009 init1: 3009 opt: 3009 Z-score: 3420.1 bits: 642.1 E(85289): 9.2e-184
Smith-Waterman score: 3009; 100.0% identity (100.0% similar) in 455 aa overlap (1-455:1-455)
10 20 30 40 50 60
pF1KE6 MGWGGGGGCTPRPPIHQQPPERRVVTVVFLGLLLDLLAFTLLLPLLPGLLESHGRAHDPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MGWGGGGGCTPRPPIHQQPPERRVVTVVFLGLLLDLLAFTLLLPLLPGLLESHGRAHDPL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 YGSWQGGVDWFATAIGMPVEKRYNSVLFGGLIGSAFSVLQFLCAPLTGATSDCLGRRPVM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YGSWQGGVDWFATAIGMPVEKRYNSVLFGGLIGSAFSVLQFLCAPLTGATSDCLGRRPVM
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 LLCLMGVATSYAVWATSRSFAAFLASRLIGGISKGNVSLSTAIVADLGSPLARSQGMAVI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LLCLMGVATSYAVWATSRSFAAFLASRLIGGISKGNVSLSTAIVADLGSPLARSQGMAVI
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE6 GVAFSLGFTLGPMLGASLPLEMAPWFALLFAASDLLFIFCFLPETLPLEKRAPSIALGFR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GVAFSLGFTLGPMLGASLPLEMAPWFALLFAASDLLFIFCFLPETLPLEKRAPSIALGFR
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE6 DAADLLSPLALLRFSAVARGQDPPSGDRLSSLRRLGLVYFLYLFLFSGLEYTLSFLTHQR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DAADLLSPLALLRFSAVARGQDPPSGDRLSSLRRLGLVYFLYLFLFSGLEYTLSFLTHQR
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE6 FQFSSLQQGKMFFLIGLTMATIQGAYARRIHPGGEVAAVKRALLLLVPAFLLIGWGRSLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FQFSSLQQGKMFFLIGLTMATIQGAYARRIHPGGEVAAVKRALLLLVPAFLLIGWGRSLP
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE6 VLGLGLLLYSFAAAVVVPCLSSVVAGYGSPGQKGTVMGTLRSLGALARAAGPLVAASVYW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VLGLGLLLYSFAAAVVVPCLSSVVAGYGSPGQKGTVMGTLRSLGALARAAGPLVAASVYW
370 380 390 400 410 420
430 440 450
pF1KE6 LAGAQACFTTWSGLFLLPFFLLQKLSYPAQTLKAE
:::::::::::::::::::::::::::::::::::
NP_001 LAGAQACFTTWSGLFLLPFFLLQKLSYPAQTLKAE
430 440 450
>>XP_005247984 (OMIM: 610977) PREDICTED: major facilitat (480 aa)
initn: 2748 init1: 2748 opt: 2749 Z-score: 3124.4 bits: 587.4 E(85289): 2.7e-167
Smith-Waterman score: 2749; 98.1% identity (98.4% similar) in 428 aa overlap (1-428:1-425)
10 20 30 40 50 60
pF1KE6 MGWGGGGGCTPRPPIHQQPPERRVVTVVFLGLLLDLLAFTLLLPLLPGLLESHGRAHDPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MGWGGGGGCTPRPPIHQQPPERRVVTVVFLGLLLDLLAFTLLLPLLPGLLESHGRAHDPL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 YGSWQGGVDWFATAIGMPVEKRYNSVLFGGLIGSAFSVLQFLCAPLTGATSDCLGRRPVM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 YGSWQGGVDWFATAIGMPVEKRYNSVLFGGLIGSAFSVLQFLCAPLTGATSDCLGRRPVM
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 LLCLMGVATSYAVWATSRSFAAFLASRLIGGISKGNVSLSTAIVADLGSPLARSQGMAVI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 LLCLMGVATSYAVWATSRSFAAFLASRLIGGISKGNVSLSTAIVADLGSPLARSQGMAVI
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE6 GVAFSLGFTLGPMLGASLPLEMAPWFALLFAASDLLFIFCFLPETLPLEKRAPSIALGFR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GVAFSLGFTLGPMLGASLPLEMAPWFALLFAASDLLFIFCFLPETLPLEKRAPSIALGFR
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE6 DAADLLSPLALLRFSAVARGQDPPSGDRLSSLRRLGLVYFLYLFLFSGLEYTLSFLTHQR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 DAADLLSPLALLRFSAVARGQDPPSGDRLSSLRRLGLVYFLYLFLFSGLEYTLSFLTHQR
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE6 FQFSSLQQGKMFFLIGLTMATIQGAYARRIHPGGEVAAVKRALLLLVPAFLLIGWGRSLP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FQFSSLQQGKMFFLIGLTMATIQGAYARRIHPGGEVAAVKRALLLLVPAFLLIGWGRSLP
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE6 VLGLGLLLYSFAAAVVVPCLSSVVAGYGSPGQKGTVMGTLRSLGALARAAGPLVAASVYW
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VLGLGLLLYSFAAAVVVPCLSSVVAGYGSPGQKGTVMGTLRSLGALARAAGPLVAASG--
370 380 390 400 410
430 440 450
pF1KE6 LAGAQACFTTWSGLFLLPFFLLQKLSYPAQTLKAE
:: :.
XP_005 -EGAGWCWGRLGAKHLPSPPKCQPPRGLGDATVSPQCTGWPGPRPASPRGPGSFCSPSSS
420 430 440 450 460 470
>>NP_002546 (OMIM: 114480,211980,268210,602631) solute c (424 aa)
initn: 84 init1: 58 opt: 237 Z-score: 270.9 bits: 59.3 E(85289): 2.4e-08
Smith-Waterman score: 262; 25.1% identity (54.9% similar) in 386 aa overlap (84-453:57-422)
60 70 80 90 100 110
pF1KE6 GRAHDPLYGSWQGGVDWFATAIGMPVEKRYNSVLFGGLIGSAFSVLQFLCAPLTGATSDC
.:. :: : ..:.:::.: .:. : .:
NP_002 LLTYVLAATELTCLFMQFSIVPYLSRKLGLDSIAFGYL-QTTFGVLQLLGGPVFGRFADQ
30 40 50 60 70 80
120 130 140 150 160
pF1KE6 LGRRPVMLLCLMGVATSYAVWATSRSFAA-----FLASRLIGGISKGNVSLSTAIVADLG
: : .. : .... . : . :.. : : ..:::: :.. . .. . ...::.
NP_002 RGARAALTLSFLAALALYLLLAAASSPALPGVYLLFASRLPGALMH-TLPAAQMVITDLS
90 100 110 120 130 140
170 180 190 200 210 220
pF1KE6 SPLARSQGMAVIGVAFSLGFTLGPMLGASLPLEMAPWF-ALLFAASDLL---FIFCFLPE
.: : ... .:. :..: :: .::..: .. :.: : . :: . : .:
NP_002 APEERPAALGRLGLCFGVGVILGSLLGGTLVSAYGIQCPAILAALATLLGAVLSFTCIPA
150 160 170 180 190 200
230 240 250 260 270 280
pF1KE6 TLPLEKRAPSIAL--GFRDAA-DLLSPLALLRFSAVARGQDPPSGDRLSSLRRLGLVYFL
. : . : : : .. :: . .:::. : : ...: :: :.
NP_002 STKGAKTDAQAPLPGGPRASVFDLKAIASLLRLPDVPR----IFLVKVASNCPTGL--FM
210 220 230 240 250
290 300 310 320 330
pF1KE6 YLFLFSGLEYTLSFLTHQRFQFSSLQQGKMFFLIGLTMATIQGAYARRI--HPGGEVAAV
.: :... . ::. . : : .. ..:: . . :: .. : . :: .
NP_002 VMF---------SIISMDFFQLEAAQAGYLMSFFGLLQMVTQGLVIGQLSSHFSEEVL-L
260 270 280 290 300
340 350 360 370 380 390
pF1KE6 KRALLLLVPAFLLIGWGRSLPVLGLGL--LLYSFAAAVVVPCLSSVVAGYGSPGQKGTVM
. ..:... . : ..: :. . : . :..:. . :: .:.. : .. ::..
NP_002 RASVLVFIVVGLAMAWMSSVFHFCLLVPGLVFSLCTLNVVT--DSMLIKAVSTSDTGTML
310 320 330 340 350 360
400 410 420 430 440 450
pF1KE6 GTLRSLGALARAAGPLVAASVYWLAGAQACFTTWSGLFLLPFFLLQKLSYPAQTLKAE
: :. : :. :: :.. .: :. . . .. : ...: . .: . :
NP_002 GLCASVQPLLRTLGPTVGGLLYRSFGVPVFGHVQVAINTLVLLVLWRKPMPQRKDKVR
370 380 390 400 410 420
>>NP_899056 (OMIM: 114480,211980,268210,602631) solute c (424 aa)
initn: 84 init1: 58 opt: 237 Z-score: 270.9 bits: 59.3 E(85289): 2.4e-08
Smith-Waterman score: 262; 25.1% identity (54.9% similar) in 386 aa overlap (84-453:57-422)
60 70 80 90 100 110
pF1KE6 GRAHDPLYGSWQGGVDWFATAIGMPVEKRYNSVLFGGLIGSAFSVLQFLCAPLTGATSDC
.:. :: : ..:.:::.: .:. : .:
NP_899 LLTYVLAATELTCLFMQFSIVPYLSRKLGLDSIAFGYL-QTTFGVLQLLGGPVFGRFADQ
30 40 50 60 70 80
120 130 140 150 160
pF1KE6 LGRRPVMLLCLMGVATSYAVWATSRSFAA-----FLASRLIGGISKGNVSLSTAIVADLG
: : .. : .... . : . :.. : : ..:::: :.. . .. . ...::.
NP_899 RGARAALTLSFLAALALYLLLAAASSPALPGVYLLFASRLPGALMH-TLPAAQMVITDLS
90 100 110 120 130 140
170 180 190 200 210 220
pF1KE6 SPLARSQGMAVIGVAFSLGFTLGPMLGASLPLEMAPWF-ALLFAASDLL---FIFCFLPE
.: : ... .:. :..: :: .::..: .. :.: : . :: . : .:
NP_899 APEERPAALGRLGLCFGVGVILGSLLGGTLVSAYGIQCPAILAALATLLGAVLSFTCIPA
150 160 170 180 190 200
230 240 250 260 270 280
pF1KE6 TLPLEKRAPSIAL--GFRDAA-DLLSPLALLRFSAVARGQDPPSGDRLSSLRRLGLVYFL
. : . : : : .. :: . .:::. : : ...: :: :.
NP_899 STKGAKTDAQAPLPGGPRASVFDLKAIASLLRLPDVPR----IFLVKVASNCPTGL--FM
210 220 230 240 250
290 300 310 320 330
pF1KE6 YLFLFSGLEYTLSFLTHQRFQFSSLQQGKMFFLIGLTMATIQGAYARRI--HPGGEVAAV
.: :... . ::. . : : .. ..:: . . :: .. : . :: .
NP_899 VMF---------SIISMDFFQLEAAQAGYLMSFFGLLQMVTQGLVIGQLSSHFSEEVL-L
260 270 280 290 300
340 350 360 370 380 390
pF1KE6 KRALLLLVPAFLLIGWGRSLPVLGLGL--LLYSFAAAVVVPCLSSVVAGYGSPGQKGTVM
. ..:... . : ..: :. . : . :..:. . :: .:.. : .. ::..
NP_899 RASVLVFIVVGLAMAWMSSVFHFCLLVPGLVFSLCTLNVVT--DSMLIKAVSTSDTGTML
310 320 330 340 350 360
400 410 420 430 440 450
pF1KE6 GTLRSLGALARAAGPLVAASVYWLAGAQACFTTWSGLFLLPFFLLQKLSYPAQTLKAE
: :. : :. :: :.. .: :. . . .. : ...: . .: . :
NP_899 GLCASVQPLLRTLGPTVGGLLYRSFGVPVFGHVQVAINTLVLLVLWRKPMPQRKDKVR
370 380 390 400 410 420
>>NP_001302430 (OMIM: 114480,211980,268210,602631) solut (509 aa)
initn: 85 init1: 58 opt: 237 Z-score: 270.0 bits: 59.4 E(85289): 2.7e-08
Smith-Waterman score: 262; 25.1% identity (54.9% similar) in 386 aa overlap (84-453:142-507)
60 70 80 90 100 110
pF1KE6 GRAHDPLYGSWQGGVDWFATAIGMPVEKRYNSVLFGGLIGSAFSVLQFLCAPLTGATSDC
.:. :: : ..:.:::.: .:. : .:
NP_001 LLTYVLAATELTCLFMQFSIVPYLSRKLGLDSIAFGYL-QTTFGVLQLLGGPVFGRFADQ
120 130 140 150 160 170
120 130 140 150 160
pF1KE6 LGRRPVMLLCLMGVATSYAVWATSRSFAA-----FLASRLIGGISKGNVSLSTAIVADLG
: : .. : .... . : . :.. : : ..:::: :.. . .. . ...::.
NP_001 RGARAALTLSFLAALALYLLLAAASSPALPGVYLLFASRLPGALMH-TLPAAQMVITDLS
180 190 200 210 220
170 180 190 200 210 220
pF1KE6 SPLARSQGMAVIGVAFSLGFTLGPMLGASLPLEMAPWF-ALLFAASDLL---FIFCFLPE
.: : ... .:. :..: :: .::..: .. :.: : . :: . : .:
NP_001 APEERPAALGRLGLCFGVGVILGSLLGGTLVSAYGIQCPAILAALATLLGAVLSFTCIPA
230 240 250 260 270 280
230 240 250 260 270 280
pF1KE6 TLPLEKRAPSIAL--GFRDAA-DLLSPLALLRFSAVARGQDPPSGDRLSSLRRLGLVYFL
. : . : : : .. :: . .:::. : : ...: :: :.
NP_001 STKGAKTDAQAPLPGGPRASVFDLKAIASLLRLPDVPR----IFLVKVASNCPTGL--FM
290 300 310 320 330 340
290 300 310 320 330
pF1KE6 YLFLFSGLEYTLSFLTHQRFQFSSLQQGKMFFLIGLTMATIQGAYARRI--HPGGEVAAV
.: :... . ::. . : : .. ..:: . . :: .. : . :: .
NP_001 VMF---------SIISMDFFQLEAAQAGYLMSFFGLLQMVTQGLVIGQLSSHFSEEVL-L
350 360 370 380 390
340 350 360 370 380 390
pF1KE6 KRALLLLVPAFLLIGWGRSLPVLGLGL--LLYSFAAAVVVPCLSSVVAGYGSPGQKGTVM
. ..:... . : ..: :. . : . :..:. . :: .:.. : .. ::..
NP_001 RASVLVFIVVGLAMAWMSSVFHFCLLVPGLVFSLCTLNVVT--DSMLIKAVSTSDTGTML
400 410 420 430 440 450
400 410 420 430 440 450
pF1KE6 GTLRSLGALARAAGPLVAASVYWLAGAQACFTTWSGLFLLPFFLLQKLSYPAQTLKAE
: :. : :. :: :.. .: :. . . .. : ...: . .: . :
NP_001 GLCASVQPLLRTLGPTVGGLLYRSFGVPVFGHVQVAINTLVLLVLWRKPMPQRKDKVR
460 470 480 490 500
>>XP_005262954 (OMIM: 610951,611124,616170) PREDICTED: m (451 aa)
initn: 178 init1: 100 opt: 190 Z-score: 217.2 bits: 49.4 E(85289): 2.3e-05
Smith-Waterman score: 216; 25.9% identity (53.2% similar) in 378 aa overlap (88-442:75-432)
60 70 80 90 100 110
pF1KE6 DPLYGSWQGGVDWFATAIGMPVEKRYNSVLFGGLIGSAFSVLQFLCAPLTGATSDCLGRR
: : . ...:. :.. .:. : :. :.
XP_005 TMFLSSVGFSVVMMSIWPYLQKIDPTADTSFLGWVIASYSLGQMVASPIFGLWSNYRPRK
50 60 70 80 90 100
120 130 140 150 160 170
pF1KE6 -PVMLLCLMGVATS--YAVWATSRSFAAF--LASRLIGGISKGNVSLSTAIVADLGSPLA
:... :..::.. :: : . :..: . ::. :::.. . .: :
XP_005 EPLIVSILISVAANCLYAYLHIPASHNKYYMLVARGLLGIGAGNVAVVRSYTAGATSLQE
110 120 130 140 150 160
180 190 200 210 220
pF1KE6 RSQGMAVIGVAFSLGFTLGPMLG--ASLPLEMAPWFALLFAASDLLFIFCF---LPETL-
:...:: :.. .::: ::: :..: :.. : . :.:. : : ::.
XP_005 RTSSMANISMCQALGFILGPASTDEAQVPQGNIDQVAVV-AINVLFFVTLFIFALFETII
170 180 190 200 210 220
230 240 250 260 270 280
pF1KE6 -PL--EKRAPSIALGFRDAADLLSPL---ALLRFSAVARGQDPPSGDRLSSLRRLGLVYF
:: . : . . . .:. : :.. : .: . . :.: : : .:.
XP_005 TPLTMDMYAWTQEQAVLYNGIILAALGVEAVVIFLGV-KLLSKKIGERAILLGGLIVVWV
230 240 250 260 270 280
290 300 310 320 330
pF1KE6 LYLFLFSGLEYTLSFLTHQRFQFSSLQQGKM----F--FLIGLTMATIQGAYARRIHPGG
...: : . .: ..:. .:..... : ..::: . .. : : :
XP_005 GFFIL---LPWGNQF---PKIQWEDLHNNSIPNTTFGEIIIGLWKSPMEDDNER---PTG
290 300 310 320 330
340 350 360 370 380 390
pF1KE6 EVAAVKRALLLLVPAFLLIGWGRSLPVLGLGLLLYSFAAAVVVPCLSSVVAGYGSPGQKG
....: : .:.. : . : ..::: . .. . . : : . : : .:
XP_005 --CSIEQAWCLYTPVIHLAQFLTSAVLIGLGYPVCNLMSYT----LYSKILG---PKPQG
340 350 360 370 380
400 410 420 430 440 450
pF1KE6 TVMGTLRSLGALARAAGPLVAASVYWLAGAQACFTTWSGLFLLPFFLLQKLSYPAQTLKA
. :: : . :. :: ::. ..:: : . :. :...: . ::
XP_005 VYMGWLTASGSGARILGPMFISQVYAHWGPRWAFSLVCGIIVLTITLLGVVYKRLIALSV
390 400 410 420 430 440
pF1KE6 E
XP_005 RYGRIQE
450
>>XP_011518443 (OMIM: 114480,211980,268210,602631) PREDI (386 aa)
initn: 73 init1: 46 opt: 173 Z-score: 198.7 bits: 45.8 E(85289): 0.00025
Smith-Waterman score: 198; 27.1% identity (54.6% similar) in 262 aa overlap (84-329:142-386)
60 70 80 90 100 110
pF1KE6 GRAHDPLYGSWQGGVDWFATAIGMPVEKRYNSVLFGGLIGSAFSVLQFLCAPLTGATSDC
.:. :: : ..:.:::.: .:. : .:
XP_011 LLTYVLAATELTCLFMQFSIVPYLSRKLGLDSIAFGYL-QTTFGVLQLLGGPVFGRFADQ
120 130 140 150 160 170
120 130 140 150 160
pF1KE6 LGRRPVMLLCLMGVATSYAVWATSRSFAA-----FLASRLIGGISKGNVSLSTAIVADLG
: : .. : .... . : . :.. : : ..:::: :.. . .. . ...::.
XP_011 RGARAALTLSFLAALALYLLLAAASSPALPGVYLLFASRLPGALMH-TLPAAQMVITDLS
180 190 200 210 220
170 180 190 200 210 220
pF1KE6 SPLARSQGMAVIGVAFSLGFTLGPMLGASLPLEMAPWF-ALLFAASDLL---FIFCFLPE
.: : ... .:. :..: :: .::..: .. :.: : . :: . : .:
XP_011 APEERPAALGRLGLCFGVGVILGSLLGGTLVSAYGIQCPAILAALATLLGAVLSFTCIPA
230 240 250 260 270 280
230 240 250 260 270 280
pF1KE6 TLPLEKRAPSIAL--GFRDAA-DLLSPLALLRFSAVARGQDPPSGDRLSSLRRLGLVYFL
. : . : : : .. :: . .:::. : : ...: :: :.
XP_011 STKGAKTDAQAPLPGGPRASVFDLKAIASLLRLPDVPR----IFLVKVASNCPTGL--FM
290 300 310 320 330 340
290 300 310 320 330
pF1KE6 YLFLFSGLEYTLSFLTHQRFQFSSLQQGKMFFLIGLT-MATI---QGAYARRIHPGGEVA
.: :... . ::. . : : .. ..:: :: . :: . :
XP_011 VMF---------SIISMDFFQLEAAQAGYLMSFFGLLQMAKVPALQGPWQMR
350 360 370 380
340 350 360 370 380 390
pF1KE6 AVKRALLLLVPAFLLIGWGRSLPVLGLGLLLYSFAAAVVVPCLSSVVAGYGSPGQKGTVM
>>XP_011518444 (OMIM: 114480,211980,268210,602631) PREDI (379 aa)
initn: 73 init1: 46 opt: 167 Z-score: 192.0 bits: 44.5 E(85289): 0.00059
Smith-Waterman score: 192; 26.8% identity (55.3% similar) in 246 aa overlap (84-317:142-370)
60 70 80 90 100 110
pF1KE6 GRAHDPLYGSWQGGVDWFATAIGMPVEKRYNSVLFGGLIGSAFSVLQFLCAPLTGATSDC
.:. :: : ..:.:::.: .:. : .:
XP_011 LLTYVLAATELTCLFMQFSIVPYLSRKLGLDSIAFGYL-QTTFGVLQLLGGPVFGRFADQ
120 130 140 150 160 170
120 130 140 150 160
pF1KE6 LGRRPVMLLCLMGVATSYAVWATSRSFAA-----FLASRLIGGISKGNVSLSTAIVADLG
: : .. : .... . : . :.. : : ..:::: :.. . .. . ...::.
XP_011 RGARAALTLSFLAALALYLLLAAASSPALPGVYLLFASRLPGALMH-TLPAAQMVITDLS
180 190 200 210 220
170 180 190 200 210 220
pF1KE6 SPLARSQGMAVIGVAFSLGFTLGPMLGASLPLEMAPWF-ALLFAASDLL---FIFCFLPE
.: : ... .:. :..: :: .::..: .. :.: : . :: . : .:
XP_011 APEERPAALGRLGLCFGVGVILGSLLGGTLVSAYGIQCPAILAALATLLGAVLSFTCIPA
230 240 250 260 270 280
230 240 250 260 270 280
pF1KE6 TLPLEKRAPSIAL--GFRDAA-DLLSPLALLRFSAVARGQDPPSGDRLSSLRRLGLVYFL
. : . : : : .. :: . .:::. : : ...: :: :.
XP_011 STKGAKTDAQAPLPGGPRASVFDLKAIASLLRLPDVPR----IFLVKVASNCPTGL--FM
290 300 310 320 330 340
290 300 310 320 330 340
pF1KE6 YLFLFSGLEYTLSFLTHQRFQFSSLQQGKMFFLIGLTMATIQGAYARRIHPGGEVAAVKR
.: :... . ::. . : : .. ..::
XP_011 VMF---------SIISMDFFQLEAAQAGYLMSFFGLLQMGPWQMR
350 360 370
350 360 370 380 390 400
pF1KE6 ALLLLVPAFLLIGWGRSLPVLGLGLLLYSFAAAVVVPCLSSVVAGYGSPGQKGTVMGTLR
>>NP_001258640 (OMIM: 605245) solute carrier family 2, f (411 aa)
initn: 134 init1: 83 opt: 165 Z-score: 189.3 bits: 44.1 E(85289): 0.00084
Smith-Waterman score: 207; 22.4% identity (51.9% similar) in 441 aa overlap (13-443:15-402)
10 20 30 40 50
pF1KE6 MGWGGGGGCTPRPPIHQQPPERRVVTVVFLGLLLDLLAFTLLLPLLPGLLESHGRAHD
:: . : ::: ..: . : :.: . : . : ::
NP_001 MTPEDPEETQPLLGPPGGSAPRGRRVFLAAFAAAL-GPLSFGFALGYSSPAIPSLQRAAP
10 20 30 40 50
60 70 80 90 100 110
pF1KE6 PLYGSWQGGVDWFATAIGMPVEKRYNSVLFGGLIGSAFSVLQFLCAPLTGATSDCLGRRP
: .....::.... . . ::..: : : ::.
NP_001 PAPRLDDAAASWFGAVVTLGAAA-------GGVLG--------------GWLVDRAGRKL
60 70 80 90
120 130 140 150 160 170
pF1KE6 VMLLCLMGVATSYAVWATSRSFAAFLASRLIGGISKGNVSLSTAI-VADLGSPLARSQGM
.::: . ....:: ..... .:..::. :.. : .:: . . ..... : .:.
NP_001 SLLLCSVPFVAGFAVITAAQDVWMLLGGRLLTGLACGVASLVAPVYISEIAYPAVRGLLG
100 110 120 130 140 150
180 190 200 210 220 230
pF1KE6 AVIGVAFSLGFTLGPMLGASLPLEMAPWFALL--FAASDLLFIFCFLPETLPLEKRAPSI
. . . .:. :. . : : . :.:.: : .:...::.::: : .
NP_001 SCVQLMVVVGILLAYLAGWVLEWR---WLAVLGCVPPSLMLLLMCFMPET-------PRF
160 170 180 190 200
240 250 260 270 280 290
pF1KE6 ALGFRDAADLLSPLALLRFSAVARGQDPPSGDRLSSLRRLGLVYFLYLFLFSGLEYTLSF
: . . .. : .: ... .::: : . : . :. . ... . .:.
NP_001 LLTQHRRQEAMAALRFL-WGSEQGWEDPPIGAEQS----FHLALLRQPGIYKPFIIGVSL
210 220 230 240 250 260
300 310 320 330 340 350
pF1KE6 LTHQRFQFSSLQQGKMFFLIGLTMATIQGAYARRIHPGGEVAAVKRALLLLVPAFLLIGW
.. : :.:... . ::. . . .. : . .. :..: ..:. : :...
NP_001 MAFQ--QLSGVN-AVMFY----AETIFEEAKFKDSSLASVVVGVIQVLFTAVAALIMDRA
270 280 290 300 310
360 370 380 390 400 410
pF1KE6 GRSLPVLGLGLLLYSFAAAVVVPCLSSVVAGYGSPGQKGTVMGTLRSLGALARAAGPLVA
:: : ::. : .::. .:. ..: . : : .. ...: . : ..
NP_001 GRRL------LLVLS---GVVMVFSTSAFGAYFKLTQGGPGNSSHVAISAPVSAQPVDAS
320 330 340 350 360
420 430 440 450
pF1KE6 ASVYWLAGAQACF-------TTWSGLFLLPFFLLQKLSYPAQTLKAE
... ::: .. :. . :: : : :. ::
NP_001 VGLAWLAVGSMCLFIAGGPQALWSLLACLRFLHLQCPFHFVLCP
370 380 390 400 410
455 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Nov 8 13:20:43 2016 done: Tue Nov 8 13:20:45 2016
Total Scan time: 8.530 Total Display time: 0.070
Function used was FASTA [36.3.4 Apr, 2011]