Result of FASTA (ccds) for
pFN21AE6439
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE6439, 476 aa
1>>>pF1KE6439 476 - 476 aa - 476 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.4253+/-0.000885; mu= 16.6815+/- 0.053
mean_var=60.5166+/-12.106, 0's: 0 Z-trim(105.2): 22 B-trim: 8 in 1/46
Lambda= 0.164868
statistics sampled from 8294 (8304) to 8294 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.642), E-opt: 0.2 (0.255), width: 16
Scan time: 2.180
The best scores are: opt bits E(32554)
CCDS5419.1 CPVL gene_id:54504|Hs108|chr7 ( 476) 3263 784.8 0
CCDS46609.1 CTSA gene_id:5476|Hs108|chr20 ( 480) 555 140.7 3.3e-33
CCDS13385.2 CTSA gene_id:5476|Hs108|chr20 ( 498) 555 140.7 3.4e-33
CCDS11593.1 SCPEP1 gene_id:59342|Hs108|chr17 ( 452) 440 113.3 5.4e-25
CCDS54467.1 CTSA gene_id:5476|Hs108|chr20 ( 481) 338 89.1 1.2e-17
>>CCDS5419.1 CPVL gene_id:54504|Hs108|chr7 (476 aa)
initn: 3263 init1: 3263 opt: 3263 Z-score: 4190.7 bits: 784.8 E(32554): 0
Smith-Waterman score: 3263; 99.8% identity (100.0% similar) in 476 aa overlap (1-476:1-476)
10 20 30 40 50 60
pF1KE6 MVGAMWKVIVSLVLLMPGPCDGLFRSLYRSVSMPPKGDSGQPLFLTPYIEAGKIQKGREL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 MVGAMWKVIVSLVLLMPGPCDGLFRSLYRSVSMPPKGDSGQPLFLTPYIEAGKIQKGREL
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 SLVGPFPGLNMKSYAGFLTVNKTYNSNLFFWFFPAQIQPEDAPVVLWLQGGPGGSSMFGL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 SLVGPFPGLNMKSYAGFLTVNKTYNSNLFFWFFPAQIQPEDAPVVLWLQGGPGGSSMFGL
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 FVEHGPYVVTSNMTLRDRDFPWTTTLSMLYIDNPVGTGFSFTDDTHGYAVNEDDVARDLY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 FVEHGPYVVTSNMTLRDRDFPWTTTLSMLYIDNPVGTGFSFTDDTHGYAVNEDDVARDLY
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE6 SALIQFFQIFPEYKNNDFYVTGESYAGKYVPAIAHLIHSLNPVREVKINLNGIAIGDGYS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 SALIQFFQIFPEYKNNDFYVTGESYAGKYVPAIAHLIHSLNPVREVKINLNGIAIGDGYS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE6 DPESIIGGYAEFLYQIGLLDEKQKKYFQKQCHECIEHIRKQNWFEAFEILDKLLDGDLTS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 DPESIIGGYAEFLYQIGLLDEKQKKYFQKQCHECIEHIRKQNWFEAFEILDKLLDGDLTS
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE6 DPSYFQNVTGCSNYYNFLRCTEPEDQLYYVKFLSLPEVRQAIHVGNQTFNDGTIVEKYLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 DPSYFQNVTGCSNYYNFLRCTEPEDQLYYVKFLSLPEVRQAIHVGNQTFNDGTIVEKYLR
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE6 EDTVQSVKPWLTEIMNNYKVLIYNGQLDIIVAAALTERSLMGMDWKGSQEYKKAEKKVWK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 EDTVQSVKPWLTEIMNNYKVLIYNGQLDIIVAAALTERSLMGMDWKGSQEYKKAEKKVWK
370 380 390 400 410 420
430 440 450 460 470
pF1KE6 IFKSDSEVAGYIRQVGDFHQVIIRGGGHILPYDQPLRAFDMINRFIYGKGWDPYVG
::::::::::::::.:::::::::::::::::::::::::::::::::::::::::
CCDS54 IFKSDSEVAGYIRQAGDFHQVIIRGGGHILPYDQPLRAFDMINRFIYGKGWDPYVG
430 440 450 460 470
>>CCDS46609.1 CTSA gene_id:5476|Hs108|chr20 (480 aa)
initn: 534 init1: 337 opt: 555 Z-score: 709.6 bits: 140.7 E(32554): 3.3e-33
Smith-Waterman score: 669; 30.5% identity (61.1% similar) in 455 aa overlap (66-466:38-475)
40 50 60 70 80 90
pF1KE6 KGDSGQPLFLTPYIEAGKIQKGRELSLVGPFPGL----NMKSYAGFLTVNKTYNSNLFFW
.::: ....:.:.: . . ...: .:
CCDS46 PLFLLLLLLLLLVSWASRGEAAPDQDEIQRLPGLAKQPSFRQYSGYL--KGSGSKHLHYW
10 20 30 40 50 60
100 110 120 130 140 150
pF1KE6 FFPAQIQPEDAPVVLWLQGGPGGSSMFGLFVEHGPYVVTSN-MTLRDRDFPWTTTLSMLY
: .: .::..::::::.:::: ::. ::..::::..: . .::. . :. ..::
CCDS46 FVESQKDPENSPVVLWLNGGPGCSSLDGLLTEHGPFLVQPDGVTLEYNPYSWNLIANVLY
70 80 90 100 110 120
160 170 180 190 200 210
pF1KE6 IDNPVGTGFSFTDDTHGYAVNEDDVARDLYSALIQFFQIFPEYKNNDFYVTGESYAGKYV
...:.:.:::..:: ::.:. .::.. . :: .::..::::::: ...::::::: :.
CCDS46 LESPAGVGFSYSDDKF-YATNDTEVAQSNFEALQDFFRLFPEYKNNKLFLTGESYAGIYI
130 140 150 160 170 180
220 230 240 250 260 270
pF1KE6 PAIAHLIHSLNPVREVKINLNGIAIGDGYSDPESIIGGYAEFLYQIGLLDEKQKKYFQKQ
:..: :. . .: ..::.:.:.:.: :. :. .. . : : ::: .. . .: .
CCDS46 PTLAVLVMQ-DP----SMNLQGLAVGNGLSSYEQNDNSLVYFAYYHGLLGNRLWSSLQTH
190 200 210 220 230
280 290 300
pF1KE6 C---HECIEHIRKQ-----NWFEAFEILDK--LLDGDLTSD-----PSYFQN------VT
: ..: . :. : :. .:. . : .: . ::.:. :
CCDS46 CCSQNKCNFYDNKDLECVTNLQEVARIVGNSGLNIYNLYAPCAGGVPSHFRYEKDTVVVQ
240 250 260 270 280 290
310 320 330 340
pF1KE6 GCSNYYNFL-----------------RCTEP-EDQLYYVKFLSLPEVRQAIHVGNQT---
.: .. : : : . .:. : ::.:... .:
CCDS46 DLGNIFTRLPLKRMWHQALLRSGDKVRMDPPCTNTTAASTYLNNPYVRKALNIPEQLPQW
300 310 320 330 340 350
350 360 370 380 390 400
pF1KE6 -FNDGTIVEKYLREDTVQSVKPWLTEIMNN--YKVLIYNGQLDIIVAAALTERSLMGMDW
. . . .: : .:.. ..... :..:.:::..:. ..:: .:
CCDS46 DMCNFLVNLQYRR--LYRSMNSQYLKLLSSQKYQILLYNGDVDMAC-------NFMGDEW
360 370 380 390 400 410
410 420 430 440 450 460
pF1KE6 KGSQEYKKAE--KKVWKIFKSDS--EVAGYIRQVGDFHQVIIRGGGHILPYDQPLRAFDM
.. .: : .. : . .:: ..::.... . . . :.:.::..: :.:: :: :
CCDS46 FVDSLNQKMEVQRRPWLVKYGDSGEQIAGFVKEFSHIAFLTIKGAGHMVPTDKPLAAFTM
420 430 440 450 460 470
470
pF1KE6 INRFIYGKGWDPYVG
..::.
CCDS46 FSRFLNKQPY
480
>>CCDS13385.2 CTSA gene_id:5476|Hs108|chr20 (498 aa)
initn: 534 init1: 337 opt: 555 Z-score: 709.3 bits: 140.7 E(32554): 3.4e-33
Smith-Waterman score: 669; 30.5% identity (61.1% similar) in 455 aa overlap (66-466:56-493)
40 50 60 70 80 90
pF1KE6 KGDSGQPLFLTPYIEAGKIQKGRELSLVGPFPGL----NMKSYAGFLTVNKTYNSNLFFW
.::: ....:.:.: . . ...: .:
CCDS13 PLFLLLLLLLLLVSWASRGEAAPDQDEIQRLPGLAKQPSFRQYSGYL--KGSGSKHLHYW
30 40 50 60 70 80
100 110 120 130 140 150
pF1KE6 FFPAQIQPEDAPVVLWLQGGPGGSSMFGLFVEHGPYVVTSN-MTLRDRDFPWTTTLSMLY
: .: .::..::::::.:::: ::. ::..::::..: . .::. . :. ..::
CCDS13 FVESQKDPENSPVVLWLNGGPGCSSLDGLLTEHGPFLVQPDGVTLEYNPYSWNLIANVLY
90 100 110 120 130 140
160 170 180 190 200 210
pF1KE6 IDNPVGTGFSFTDDTHGYAVNEDDVARDLYSALIQFFQIFPEYKNNDFYVTGESYAGKYV
...:.:.:::..:: ::.:. .::.. . :: .::..::::::: ...::::::: :.
CCDS13 LESPAGVGFSYSDDKF-YATNDTEVAQSNFEALQDFFRLFPEYKNNKLFLTGESYAGIYI
150 160 170 180 190 200
220 230 240 250 260 270
pF1KE6 PAIAHLIHSLNPVREVKINLNGIAIGDGYSDPESIIGGYAEFLYQIGLLDEKQKKYFQKQ
:..: :. . .: ..::.:.:.:.: :. :. .. . : : ::: .. . .: .
CCDS13 PTLAVLVMQ-DP----SMNLQGLAVGNGLSSYEQNDNSLVYFAYYHGLLGNRLWSSLQTH
210 220 230 240 250
280 290 300
pF1KE6 C---HECIEHIRKQ-----NWFEAFEILDK--LLDGDLTSD-----PSYFQN------VT
: ..: . :. : :. .:. . : .: . ::.:. :
CCDS13 CCSQNKCNFYDNKDLECVTNLQEVARIVGNSGLNIYNLYAPCAGGVPSHFRYEKDTVVVQ
260 270 280 290 300 310
310 320 330 340
pF1KE6 GCSNYYNFL-----------------RCTEP-EDQLYYVKFLSLPEVRQAIHVGNQT---
.: .. : : : . .:. : ::.:... .:
CCDS13 DLGNIFTRLPLKRMWHQALLRSGDKVRMDPPCTNTTAASTYLNNPYVRKALNIPEQLPQW
320 330 340 350 360 370
350 360 370 380 390 400
pF1KE6 -FNDGTIVEKYLREDTVQSVKPWLTEIMNN--YKVLIYNGQLDIIVAAALTERSLMGMDW
. . . .: : .:.. ..... :..:.:::..:. ..:: .:
CCDS13 DMCNFLVNLQYRR--LYRSMNSQYLKLLSSQKYQILLYNGDVDMAC-------NFMGDEW
380 390 400 410 420
410 420 430 440 450 460
pF1KE6 KGSQEYKKAE--KKVWKIFKSDS--EVAGYIRQVGDFHQVIIRGGGHILPYDQPLRAFDM
.. .: : .. : . .:: ..::.... . . . :.:.::..: :.:: :: :
CCDS13 FVDSLNQKMEVQRRPWLVKYGDSGEQIAGFVKEFSHIAFLTIKGAGHMVPTDKPLAAFTM
430 440 450 460 470 480
470
pF1KE6 INRFIYGKGWDPYVG
..::.
CCDS13 FSRFLNKQPY
490
>>CCDS11593.1 SCPEP1 gene_id:59342|Hs108|chr17 (452 aa)
initn: 476 init1: 300 opt: 440 Z-score: 562.2 bits: 113.3 E(32554): 5.4e-25
Smith-Waterman score: 525; 27.2% identity (56.7% similar) in 434 aa overlap (57-462:22-445)
30 40 50 60 70 80
pF1KE6 LYRSVSMPPKGDSGQPLFLTPYIEAGKIQKGRELSLVGPFPGLNMKSYAGFLTVNKTYNS
: . . : .: . : ..:: : ..
CCDS11 MELALRRSPVPRWLLLLPLLLGLNAGAVIDWPTEEGKEVWDYVTVRK--DA
10 20 30 40
90 100 110 120 130 140
pF1KE6 NLFFWFFPAQIQPED---APVVLWLQGGPGGSSM-FGLFVEHGPYVVTSNMTLRDRDFPW
.:.:.. : . .. :.:.:::::::::: :: : : :: . :. : :
CCDS11 YMFWWLYYATNSCKNFSELPLVMWLQGGPGGSSTGFGNFEEIGPL----DSDLKPRKTTW
50 60 70 80 90 100
150 160 170 180 190 200
pF1KE6 TTTLSMLYIDNPVGTGFSFTDDTHGYAVNEDDVARDLYSALIQFFQIFPEYKNNDFYVTG
. :.:..:::::::::... . .:: . :: :.. : ::. :... ::. .
CCDS11 LQAASLLFVDNPVGTGFSYVNGSGAYAKDLAMVASDMMVLLKTFFSCHKEFQTVPFYIFS
110 120 130 140 150 160
210 220 230 240 250 260
pF1KE6 ESYAGKYVPAIAHLIHSLNPVREVKINLNGIAIGDGYSDPESIIGGYAEFLYQIGLLDEK
:::.::.. .:. ... .: :. :.:.::.. .: . . ... .::...::..:
CCDS11 ESYGGKMAAGIGLELYKAIQRGTIKCNFAGVALGDSWISPVDSVLSWGPYLYSMSLLEDK
170 180 190 200 210 220
270 280 290 300 310 320
pF1KE6 QKKYFQKQCHECIEHIRKQNWFEAFEILDKL-LDGDLTSDPSYFQNVTGCSNYYNFLRCT
.: .. .. . : . :: :. : . . ..: : :. :. . .. .
CCDS11 GLAEVSKVAEQVLNAVNKGLYREATELWGKAEMIIEQNTDGVNFYNILTKSTPTSTMESS
230 240 250 260 270 280
330 340 350 360
pF1KE6 EPEDQLYYV----------------KFLSLPEVRQAIHV--GNQTFN-DGTIVEKYLRED
: . : .... : .:. ... .:... ..: : ..::
CCDS11 LEFTQSHLVCLCQRHVRHLQRDALSQLMNGP-IRKKLKIIPEDQSWGGQATNVFVNMEED
290 300 310 320 330 340
370 380 390 400 410 420
pF1KE6 TVQSVKPWLTEIMN-NYKVLIYNGQLDIIVAAALTERSLMGMDWKGSQEYKKAEKKVWKI
.. : . :... . .: .::::::.:: . : . . : : : . ::
CCDS11 FMKPVISIVDELLEAGINVTVYNGQLDLIVDTMGQEAWVRKLKWP---ELPKFSQLKWKA
350 360 370 380 390 400
430 440 450 460 470
pF1KE6 FKSDS---EVAGYIRQVGDFHQVIIRGGGHILPYDQPLRAFDMINRFIYGKGWDPYVG
. :: :....... .. : .::..: :: :. :.
CCDS11 LYSDPKSLETSAFVKSYKNLAFYWILKAGHMVPSDQGDMALKMMRLVTQQE
410 420 430 440 450
>>CCDS54467.1 CTSA gene_id:5476|Hs108|chr20 (481 aa)
initn: 477 init1: 192 opt: 338 Z-score: 430.6 bits: 89.1 E(32554): 1.2e-17
Smith-Waterman score: 618; 29.7% identity (59.7% similar) in 454 aa overlap (66-466:56-476)
40 50 60 70 80 90
pF1KE6 KGDSGQPLFLTPYIEAGKIQKGRELSLVGPFPGL----NMKSYAGFLTVNKTYNSNLFFW
.::: ....:.:.: . . ...: .:
CCDS54 PLFLLLLLLLLLVSWASRGEAAPDQDEIQRLPGLAKQPSFRQYSGYL--KGSGSKHLHYW
30 40 50 60 70 80
100 110 120 130 140 150
pF1KE6 FFPAQIQPEDAPVVLWLQGGPGGSSMFGLFVEHGPYVVTSNMTLRDRDFPWTTTLSMLYI
: .: .::..::::::.:::: ::. ::..::::..... .::.
CCDS54 FVESQKDPENSPVVLWLNGGPGCSSLDGLLTEHGPFLIAN----------------VLYL
90 100 110 120
160 170 180 190 200 210
pF1KE6 DNPVGTGFSFTDDTHGYAVNEDDVARDLYSALIQFFQIFPEYKNNDFYVTGESYAGKYVP
..:.:.:::..:: ::.:. .::.. . :: .::..::::::: ...::::::: :.:
CCDS54 ESPAGVGFSYSDDKF-YATNDTEVAQSNFEALQDFFRLFPEYKNNKLFLTGESYAGIYIP
130 140 150 160 170 180
220 230 240 250 260 270
pF1KE6 AIAHLIHSLNPVREVKINLNGIAIGDGYSDPESIIGGYAEFLYQIGLLDEKQKKYFQKQC
..: :. . .: ..::.:.:.:.: :. :. .. . : : ::: .. . .: .:
CCDS54 TLAVLVMQ-DP----SMNLQGLAVGNGLSSYEQNDNSLVYFAYYHGLLGNRLWSSLQTHC
190 200 210 220 230 240
280 290 300 310
pF1KE6 ---HECIEHIRKQ-----NWFEAFEILDK--LLDGDLTSD-----PSYFQN------VTG
..: . :. : :. .:. . : .: . ::.:. :
CCDS54 CSQNKCNFYDNKDLECVTNLQEVARIVGNSGLNIYNLYAPCAGGVPSHFRYEKDTVVVQD
250 260 270 280 290 300
320 330 340
pF1KE6 CSNYYNFL-----------------RCTEP-EDQLYYVKFLSLPEVRQAIHVGNQT----
.: .. : : : . .:. : ::.:... .:
CCDS54 LGNIFTRLPLKRMWHQALLRSGDKVRMDPPCTNTTAASTYLNNPYVRKALNIPEQLPQWD
310 320 330 340 350 360
350 360 370 380 390 400
pF1KE6 FNDGTIVEKYLREDTVQSVKPWLTEIMNN--YKVLIYNGQLDIIVAAALTERSLMGMDWK
. . . .: : .:.. ..... :..:.:::..:. ..:: .:
CCDS54 MCNFLVNLQYRR--LYRSMNSQYLKLLSSQKYQILLYNGDVDMAC-------NFMGDEWF
370 380 390 400 410
410 420 430 440 450 460
pF1KE6 GSQEYKKAE--KKVWKIFKSDS--EVAGYIRQVGDFHQVIIRGGGHILPYDQPLRAFDMI
.. .: : .. : . .:: ..::.... . . . :.:.::..: :.:: :: :.
CCDS54 VDSLNQKMEVQRRPWLVKYGDSGEQIAGFVKEFSHIAFLTIKGAGHMVPTDKPLAAFTMF
420 430 440 450 460 470
470
pF1KE6 NRFIYGKGWDPYVG
.::.
CCDS54 SRFLNKQPY
480
476 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Nov 8 13:18:32 2016 done: Tue Nov 8 13:18:32 2016
Total Scan time: 2.180 Total Display time: 0.000
Function used was FASTA [36.3.4 Apr, 2011]