Result of FASTA (omim) for
pFN21AE6426
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE6426, 524 aa
1>>>pF1KE6426 524 - 524 aa - 524 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 4.8769+/-0.000369; mu= 20.6442+/- 0.023
mean_var=63.2674+/-12.660, 0's: 0 Z-trim(113.9): 186 B-trim: 170 in 1/53
Lambda= 0.161244
statistics sampled from 23197 (23398) to 23197 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.654), E-opt: 0.2 (0.274), width: 16
Scan time: 5.800
The best scores are: opt bits E(85289)
NP_076433 (OMIM: 611485) cytochrome P450 4F12 [Hom ( 524) 3608 848.2 0
NP_067010 (OMIM: 611517) phylloquinone omega-hydro ( 524) 3070 723.0 5.2e-208
NP_001122404 (OMIM: 611517) phylloquinone omega-hy ( 524) 3070 723.0 5.2e-208
NP_001073 (OMIM: 604426) phylloquinone omega-hydro ( 520) 3031 713.9 2.8e-205
XP_016882303 (OMIM: 601270) PREDICTED: docosahexae ( 520) 2990 704.4 2.1e-202
NP_001186137 (OMIM: 601270) docosahexaenoic acid o ( 520) 2990 704.4 2.1e-202
NP_001186138 (OMIM: 601270) docosahexaenoic acid o ( 520) 2990 704.4 2.1e-202
NP_009184 (OMIM: 611545) cytochrome P450 4F8 precu ( 520) 2879 678.6 1.2e-194
NP_000887 (OMIM: 601270) docosahexaenoic acid omeg ( 520) 2851 672.1 1.1e-192
XP_006722913 (OMIM: 611485) PREDICTED: cytochrome ( 375) 2561 604.5 1.8e-172
XP_011526504 (OMIM: 611485) PREDICTED: cytochrome ( 375) 2561 604.5 1.8e-172
XP_011526510 (OMIM: 611485) PREDICTED: cytochrome ( 375) 2561 604.5 1.8e-172
XP_016882661 (OMIM: 611485) PREDICTED: cytochrome ( 411) 2536 598.7 1.1e-170
XP_011526505 (OMIM: 611485) PREDICTED: cytochrome ( 352) 2397 566.3 5.1e-161
XP_011526507 (OMIM: 611485) PREDICTED: cytochrome ( 352) 2397 566.3 5.1e-161
XP_011526506 (OMIM: 611485) PREDICTED: cytochrome ( 352) 2397 566.3 5.1e-161
NP_775754 (OMIM: 611495) cytochrome P450 4F22 [Hom ( 531) 2317 547.9 2.8e-155
XP_011525994 (OMIM: 611495) PREDICTED: cytochrome ( 531) 2317 547.9 2.8e-155
XP_011525995 (OMIM: 611495) PREDICTED: cytochrome ( 531) 2317 547.9 2.8e-155
XP_011526509 (OMIM: 611485) PREDICTED: cytochrome ( 334) 2303 544.5 1.9e-154
XP_016881721 (OMIM: 611545) PREDICTED: cytochrome ( 418) 2297 543.1 5.9e-154
XP_005259968 (OMIM: 601270) PREDICTED: docosahexae ( 371) 2206 521.9 1.3e-147
XP_011526316 (OMIM: 601270) PREDICTED: docosahexae ( 371) 2206 521.9 1.3e-147
XP_016882304 (OMIM: 601270) PREDICTED: docosahexae ( 391) 2069 490.1 5.2e-138
NP_000769 (OMIM: 601310) cytochrome P450 4A11 isof ( 519) 1433 342.2 2.2e-93
NP_001093242 (OMIM: 124075) cytochrome P450 4B1 is ( 512) 1372 328.0 4.1e-89
NP_828847 (OMIM: 614999) cytochrome P450 4X1 isofo ( 509) 1364 326.2 1.5e-88
XP_016855954 (OMIM: 601310) PREDICTED: cytochrome ( 415) 1360 325.2 2.4e-88
NP_000770 (OMIM: 124075) cytochrome P450 4B1 isofo ( 511) 1356 324.3 5.5e-88
NP_001010969 (OMIM: 615341) cytochrome P450 4A22 i ( 519) 1341 320.8 6.2e-87
NP_001307218 (OMIM: 614999) cytochrome P450 4X1 is ( 508) 1325 317.1 8e-86
NP_001307219 (OMIM: 614999) cytochrome P450 4X1 is ( 444) 1323 316.6 1e-85
XP_016855955 (OMIM: 124075) PREDICTED: cytochrome ( 496) 1288 308.5 3.1e-83
NP_001306090 (OMIM: 124075) cytochrome P450 4B1 is ( 497) 1278 306.1 1.5e-82
XP_016856462 (OMIM: 614999) PREDICTED: cytochrome ( 470) 1269 304.0 6.3e-82
NP_001306092 (OMIM: 124075) cytochrome P450 4B1 is ( 348) 1129 271.4 3.2e-72
NP_001306091 (OMIM: 124075) cytochrome P450 4B1 is ( 349) 1119 269.0 1.6e-71
NP_997235 (OMIM: 210370,608614) cytochrome P450 4V ( 525) 1017 245.4 3.1e-64
XP_005262992 (OMIM: 210370,608614) PREDICTED: cyto ( 524) 1010 243.8 9.4e-64
NP_001306084 (OMIM: 601310) cytochrome P450 4A11 i ( 487) 966 233.6 1.1e-60
XP_016863526 (OMIM: 210370,608614) PREDICTED: cyto ( 393) 873 211.9 3e-54
XP_011539135 (OMIM: 124075) PREDICTED: cytochrome ( 278) 797 194.1 4.7e-49
XP_011539134 (OMIM: 124075) PREDICTED: cytochrome ( 296) 591 146.2 1.3e-34
NP_001278759 (OMIM: 145500,605325) cytochrome P450 ( 492) 576 142.8 2.2e-33
NP_000768 (OMIM: 145500,605325) cytochrome P450 3A ( 502) 576 142.8 2.2e-33
NP_059488 (OMIM: 124010) cytochrome P450 3A4 isofo ( 503) 573 142.1 3.7e-33
NP_000756 (OMIM: 605340) cytochrome P450 3A7 [Homo ( 503) 571 141.7 5e-33
NP_073731 (OMIM: 606534) cytochrome P450 3A43 isof ( 504) 568 141.0 8.2e-33
NP_476436 (OMIM: 606534) cytochrome P450 3A43 isof ( 503) 562 139.6 2.2e-32
XP_016868032 (OMIM: 606534) PREDICTED: cytochrome ( 394) 550 136.7 1.2e-31
>>NP_076433 (OMIM: 611485) cytochrome P450 4F12 [Homo sa (524 aa)
initn: 3608 init1: 3608 opt: 3608 Z-score: 4531.8 bits: 848.2 E(85289): 0
Smith-Waterman score: 3608; 99.4% identity (99.6% similar) in 524 aa overlap (1-524:1-524)
10 20 30 40 50 60
pF1KE6 MSLLSLPWLGLRPVAMSPWLLLLLVVGSWLLARILAWTYAFYNNCRRLQCFPQPPKRNWF
::::::::::::::: ::::::::::::::::::::::::::::::::::::::::::::
NP_076 MSLLSLPWLGLRPVATSPWLLLLLVVGSWLLARILAWTYAFYNNCRRLQCFPQPPKRNWF
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 WGHLGLITPTEEGLKDSTQMSATYSQGFTVWLGPIIPFIVLCHPDTIRSITNASAAIAPK
:::::::::::::::.::::::::::::::::::::::::::::::::::::::::::::
NP_076 WGHLGLITPTEEGLKNSTQMSATYSQGFTVWLGPIIPFIVLCHPDTIRSITNASAAIAPK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 DNLFIRFLKPWLGEGILLSGGDKWSRHRRMLTPAFHFNILKSYITIFNKSANIMLDKWQH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_076 DNLFIRFLKPWLGEGILLSGGDKWSRHRRMLTPAFHFNILKSYITIFNKSANIMLDKWQH
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE6 LASEGSSCLDMFEHISLMTLDSLQKCIFSFDSHCQERPSEYIATILELSALVEKRSQHIL
::::::: ::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_076 LASEGSSRLDMFEHISLMTLDSLQKCIFSFDSHCQERPSEYIATILELSALVEKRSQHIL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE6 QHMDFLYYLSHDGRRFHRACRLVHDFTDAVIRERRRTLPTQGIDDFFKDKAKSKTLDFID
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_076 QHMDFLYYLSHDGRRFHRACRLVHDFTDAVIRERRRTLPTQGIDDFFKDKAKSKTLDFID
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE6 VLLLSKDEDGKALSDEDIRAEADTFMFGGHDTTASGLSWVLYNLARHPEYQERCRQEVQE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_076 VLLLSKDEDGKALSDEDIRAEADTFMFGGHDTTASGLSWVLYNLARHPEYQERCRQEVQE
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE6 LLKDRDPKEIEWDDLAQLPFLTMCVKESLRLHPPAPFISRCCTQDIVLPDGRVIPKGITC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_076 LLKDRDPKEIEWDDLAQLPFLTMCVKESLRLHPPAPFISRCCTQDIVLPDGRVIPKGITC
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE6 LIDIIGVHHNPTVWPDPEVYDPFRFDPENSKGRSPLAFIPFSAGPRNCIGQAFAMAEMKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_076 LIDIIGVHHNPTVWPDPEVYDPFRFDPENSKGRSPLAFIPFSAGPRNCIGQAFAMAEMKV
430 440 450 460 470 480
490 500 510 520
pF1KE6 VLALMLLHFRFLPDHTEPRRKLELIMRAEGGLWLRVEPLNVSLQ
::::::::::::::::::::::::::::::::::::::::::::
NP_076 VLALMLLHFRFLPDHTEPRRKLELIMRAEGGLWLRVEPLNVSLQ
490 500 510 520
>>NP_067010 (OMIM: 611517) phylloquinone omega-hydroxyla (524 aa)
initn: 3114 init1: 3066 opt: 3070 Z-score: 3855.4 bits: 723.0 E(85289): 5.2e-208
Smith-Waterman score: 3070; 82.8% identity (92.9% similar) in 524 aa overlap (1-524:1-524)
10 20 30 40 50 60
pF1KE6 MSLLSLPWLGLRPVAMSPWLLLLLVVGSWLLARILAWTYAFYNNCRRLQCFPQPPKRNWF
: ::: :::: ::: ::::::::: :::::::.:::::.::.:::::::::::::.:::
NP_067 MPQLSLSWLGLGPVAASPWLLLLLVGGSWLLARVLAWTYTFYDNCRRLQCFPQPPKQNWF
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 WGHLGLITPTEEGLKDSTQMSATYSQGFTVWLGPIIPFIVLCHPDTIRSITNASAAIAPK
::: ::.::::::.: ::. .:: ::: .:::: .:...::::: :: ::.::::.:::
NP_067 WGHQGLVTPTEEGMKTLTQLVTTYPQGFKLWLGPTFPLLILCHPDIIRPITSASAAVAPK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 DNLFIRFLKPWLGEGILLSGGDKWSRHRRMLTPAFHFNILKSYITIFNKSANIMLDKWQH
: .: :::::::.:.::::::::::::::::::::::::: :. :::::.::: ::::.
NP_067 DMIFYGFLKPWLGDGLLLSGGDKWSRHRRMLTPAFHFNILKPYMKIFNKSVNIMHDKWQR
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE6 LASEGSSCLDMFEHISLMTLDSLQKCIFSFDSHCQERPSEYIATILELSALVEKRSQHIL
::::::. ::::::::::::::::::.:::.:.:::.::::::.::::::.::::.:.::
NP_067 LASEGSARLDMFEHISLMTLDSLQKCVFSFESNCQEKPSEYIAAILELSAFVEKRNQQIL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE6 QHMDFLYYLSHDGRRFHRACRLVHDFTDAVIRERRRTLPTQGIDDFFKDKAKSKTLDFID
: ::::::. ::.::.:::.::::::::::.::: ::::::::::.:.:::::::::::
NP_067 LHTDFLYYLTPDGQRFRRACHLVHDFTDAVIQERRCTLPTQGIDDFLKNKAKSKTLDFID
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE6 VLLLSKDEDGKALSDEDIRAEADTFMFGGHDTTASGLSWVLYNLARHPEYQERCRQEVQE
::::::::::: ::::::::::::::: ::::::::::::::.::.::::::.:::::::
NP_067 VLLLSKDEDGKELSDEDIRAEADTFMFEGHDTTASGLSWVLYHLAKHPEYQEQCRQEVQE
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE6 LLKDRDPKEIEWDDLAQLPFLTMCVKESLRLHPPAPFISRCCTQDIVLPDGRVIPKGITC
:::::.: ::::::::::::::::.:::::::::.: ::::::::.::::::::::::.:
NP_067 LLKDREPIEIEWDDLAQLPFLTMCIKESLRLHPPVPVISRCCTQDFVLPDGRVIPKGIVC
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE6 LIDIIGVHHNPTVWPDPEVYDPFRFDPENSKGRSPLAFIPFSAGPRNCIGQAFAMAEMKV
::.:::.:.::::::::::::::::: :: : ::::::::::::::::::::::::::::
NP_067 LINIIGIHYNPTVWPDPEVYDPFRFDQENIKERSPLAFIPFSAGPRNCIGQAFAMAEMKV
430 440 450 460 470 480
490 500 510 520
pF1KE6 VLALMLLHFRFLPDHTEPRRKLELIMRAEGGLWLRVEPLNVSLQ
:::: :::::.:: ::::::: :::.:::::::::::::... :
NP_067 VLALTLLHFRILPTHTEPRRKPELILRAEGGLWLRVEPLGANSQ
490 500 510 520
>>NP_001122404 (OMIM: 611517) phylloquinone omega-hydrox (524 aa)
initn: 3114 init1: 3066 opt: 3070 Z-score: 3855.4 bits: 723.0 E(85289): 5.2e-208
Smith-Waterman score: 3070; 82.8% identity (92.9% similar) in 524 aa overlap (1-524:1-524)
10 20 30 40 50 60
pF1KE6 MSLLSLPWLGLRPVAMSPWLLLLLVVGSWLLARILAWTYAFYNNCRRLQCFPQPPKRNWF
: ::: :::: ::: ::::::::: :::::::.:::::.::.:::::::::::::.:::
NP_001 MPQLSLSWLGLGPVAASPWLLLLLVGGSWLLARVLAWTYTFYDNCRRLQCFPQPPKQNWF
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 WGHLGLITPTEEGLKDSTQMSATYSQGFTVWLGPIIPFIVLCHPDTIRSITNASAAIAPK
::: ::.::::::.: ::. .:: ::: .:::: .:...::::: :: ::.::::.:::
NP_001 WGHQGLVTPTEEGMKTLTQLVTTYPQGFKLWLGPTFPLLILCHPDIIRPITSASAAVAPK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 DNLFIRFLKPWLGEGILLSGGDKWSRHRRMLTPAFHFNILKSYITIFNKSANIMLDKWQH
: .: :::::::.:.::::::::::::::::::::::::: :. :::::.::: ::::.
NP_001 DMIFYGFLKPWLGDGLLLSGGDKWSRHRRMLTPAFHFNILKPYMKIFNKSVNIMHDKWQR
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE6 LASEGSSCLDMFEHISLMTLDSLQKCIFSFDSHCQERPSEYIATILELSALVEKRSQHIL
::::::. ::::::::::::::::::.:::.:.:::.::::::.::::::.::::.:.::
NP_001 LASEGSARLDMFEHISLMTLDSLQKCVFSFESNCQEKPSEYIAAILELSAFVEKRNQQIL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE6 QHMDFLYYLSHDGRRFHRACRLVHDFTDAVIRERRRTLPTQGIDDFFKDKAKSKTLDFID
: ::::::. ::.::.:::.::::::::::.::: ::::::::::.:.:::::::::::
NP_001 LHTDFLYYLTPDGQRFRRACHLVHDFTDAVIQERRCTLPTQGIDDFLKNKAKSKTLDFID
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE6 VLLLSKDEDGKALSDEDIRAEADTFMFGGHDTTASGLSWVLYNLARHPEYQERCRQEVQE
::::::::::: ::::::::::::::: ::::::::::::::.::.::::::.:::::::
NP_001 VLLLSKDEDGKELSDEDIRAEADTFMFEGHDTTASGLSWVLYHLAKHPEYQEQCRQEVQE
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE6 LLKDRDPKEIEWDDLAQLPFLTMCVKESLRLHPPAPFISRCCTQDIVLPDGRVIPKGITC
:::::.: ::::::::::::::::.:::::::::.: ::::::::.::::::::::::.:
NP_001 LLKDREPIEIEWDDLAQLPFLTMCIKESLRLHPPVPVISRCCTQDFVLPDGRVIPKGIVC
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE6 LIDIIGVHHNPTVWPDPEVYDPFRFDPENSKGRSPLAFIPFSAGPRNCIGQAFAMAEMKV
::.:::.:.::::::::::::::::: :: : ::::::::::::::::::::::::::::
NP_001 LINIIGIHYNPTVWPDPEVYDPFRFDQENIKERSPLAFIPFSAGPRNCIGQAFAMAEMKV
430 440 450 460 470 480
490 500 510 520
pF1KE6 VLALMLLHFRFLPDHTEPRRKLELIMRAEGGLWLRVEPLNVSLQ
:::: :::::.:: ::::::: :::.:::::::::::::... :
NP_001 VLALTLLHFRILPTHTEPRRKPELILRAEGGLWLRVEPLGANSQ
490 500 510 520
>>NP_001073 (OMIM: 604426) phylloquinone omega-hydroxyla (520 aa)
initn: 3055 init1: 3031 opt: 3031 Z-score: 3806.4 bits: 713.9 E(85289): 2.8e-205
Smith-Waterman score: 3031; 81.9% identity (92.7% similar) in 520 aa overlap (1-520:1-520)
10 20 30 40 50 60
pF1KE6 MSLLSLPWLGLRPVAMSPWLLLLLVVGSWLLARILAWTYAFYNNCRRLQCFPQPPKRNWF
:: ::: :::: ::: ::::::::: .:::::..::::::::.:::::.::::::.::::
NP_001 MSQLSLSWLGLWPVAASPWLLLLLVGASWLLAHVLAWTYAFYDNCRRLRCFPQPPRRNWF
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 WGHLGLITPTEEGLKDSTQMSATYSQGFTVWLGPIIPFIVLCHPDTIRSITNASAAIAPK
::: :...:::::.. ::. ::: ::: ::.::: :.. ::::: :::. :::::::::
NP_001 WGHQGMVNPTEEGMRVLTQLVATYPQGFKVWMGPISPLLSLCHPDIIRSVINASAAIAPK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 DNLFIRFLKPWLGEGILLSGGDKWSRHRRMLTPAFHFNILKSYITIFNKSANIMLDKWQH
:..: ::.::::.:.:::.::::::::::::::::::::: :. :::.:.::: :::
NP_001 DKFFYSFLEPWLGDGLLLSAGDKWSRHRRMLTPAFHFNILKPYMKIFNESVNIMHAKWQL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE6 LASEGSSCLDMFEHISLMTLDSLQKCIFSFDSHCQERPSEYIATILELSALVEKRSQHIL
::::::.:::::::::::::::::::.:::::::::.::::::.:::::::: :: ..::
NP_001 LASEGSACLDMFEHISLMTLDSLQKCVFSFDSHCQEKPSEYIAAILELSALVSKRHHEIL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE6 QHMDFLYYLSHDGRRFHRACRLVHDFTDAVIRERRRTLPTQGIDDFFKDKAKSKTLDFID
:.::::::. ::.::.::::::::::::::.:::::::.::.:::.. :::::::::::
NP_001 LHIDFLYYLTPDGQRFRRACRLVHDFTDAVIQERRRTLPSQGVDDFLQAKAKSKTLDFID
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE6 VLLLSKDEDGKALSDEDIRAEADTFMFGGHDTTASGLSWVLYNLARHPEYQERCRQEVQE
::::::::::: ::::::::::::::: ::::::::::::::.::.::::::::::::::
NP_001 VLLLSKDEDGKKLSDEDIRAEADTFMFEGHDTTASGLSWVLYHLAKHPEYQERCRQEVQE
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE6 LLKDRDPKEIEWDDLAQLPFLTMCVKESLRLHPPAPFISRCCTQDIVLPDGRVIPKGITC
:::::.::::::::::.:::::::.:::::::::.: ::: :::::::::::::::: :
NP_001 LLKDREPKEIEWDDLAHLPFLTMCMKESLRLHPPVPVISRHVTQDIVLPDGRVIPKGIIC
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE6 LIDIIGVHHNPTVWPDPEVYDPFRFDPENSKGRSPLAFIPFSAGPRNCIGQAFAMAEMKV
::...:.::::.::::::::::::::::: : :::::::::::::::::::.::::::::
NP_001 LISVFGTHHNPAVWPDPEVYDPFRFDPENIKERSPLAFIPFSAGPRNCIGQTFAMAEMKV
430 440 450 460 470 480
490 500 510 520
pF1KE6 VLALMLLHFRFLPDHTEPRRKLELIMRAEGGLWLRVEPLNVSLQ
:::: ::.:: :::::::::: ::..:::::::::::::.
NP_001 VLALTLLRFRVLPDHTEPRRKPELVLRAEGGLWLRVEPLS
490 500 510 520
>>XP_016882303 (OMIM: 601270) PREDICTED: docosahexaenoic (520 aa)
initn: 3010 init1: 2986 opt: 2990 Z-score: 3754.9 bits: 704.4 E(85289): 2.1e-202
Smith-Waterman score: 2990; 81.3% identity (92.3% similar) in 520 aa overlap (1-520:1-520)
10 20 30 40 50 60
pF1KE6 MSLLSLPWLGLRPVAMSPWLLLLLVVGSWLLARILAWTYAFYNNCRRLQCFPQPPKRNWF
: ::: ::: :.: ::::::::: .::::::::::::.::.:: ::.:::::::::::
XP_016 MPQLSLSSLGLWPMAASPWLLLLLVGASWLLARILAWTYTFYDNCCRLRCFPQPPKRNWF
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 WGHLGLITPTEEGLKDSTQMSATYSQGFTVWLGPIIPFIVLCHPDTIRSITNASAAIAPK
:::::.::::.:.. ::. ::: ::: ::.:::.: : .:::. :::. ::::::.::
XP_016 LGHLGLVTPTEQGMRVLTQLVATYPQGFKVWMGPIFPVIRFCHPNIIRSVINASAAIVPK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 DNLFIRFLKPWLGEGILLSGGDKWSRHRRMLTPAFHFNILKSYITIFNKSANIMLDKWQH
:..: :::::::.:.:::.:.::::::::::::::::::: :. :::.:.::: :::
XP_016 DKVFYSFLKPWLGDGLLLSAGEKWSRHRRMLTPAFHFNILKPYMKIFNESVNIMHAKWQL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE6 LASEGSSCLDMFEHISLMTLDSLQKCIFSFDSHCQERPSEYIATILELSALVEKRSQHIL
::::::. ::::::::::::::::::.:::::::::.::::::.:::::::: :: :.::
XP_016 LASEGSARLDMFEHISLMTLDSLQKCVFSFDSHCQEKPSEYIAAILELSALVTKRHQQIL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE6 QHMDFLYYLSHDGRRFHRACRLVHDFTDAVIRERRRTLPTQGIDDFFKDKAKSKTLDFID
..::::::. ::.::.::::::::::::::.:::::::.::.:::.. :::::::::::
XP_016 LYIDFLYYLTPDGQRFRRACRLVHDFTDAVIQERRRTLPSQGVDDFLQAKAKSKTLDFID
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE6 VLLLSKDEDGKALSDEDIRAEADTFMFGGHDTTASGLSWVLYNLARHPEYQERCRQEVQE
::::::::::: ::::::::::::::: ::::::::::::::.::.::::::::::::::
XP_016 VLLLSKDEDGKKLSDEDIRAEADTFMFEGHDTTASGLSWVLYHLAKHPEYQERCRQEVQE
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE6 LLKDRDPKEIEWDDLAQLPFLTMCVKESLRLHPPAPFISRCCTQDIVLPDGRVIPKGITC
:::::.::::::::::::::::::.:::::::::.: .:::::::::::::::::::: :
XP_016 LLKDREPKEIEWDDLAQLPFLTMCIKESLRLHPPVPAVSRCCTQDIVLPDGRVIPKGIIC
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE6 LIDIIGVHHNPTVWPDPEVYDPFRFDPENSKGRSPLAFIPFSAGPRNCIGQAFAMAEMKV
::...:.::::.:::::::::::::::.: : ::::::::::::::::::::::::::::
XP_016 LISVFGTHHNPAVWPDPEVYDPFRFDPKNIKERSPLAFIPFSAGPRNCIGQAFAMAEMKV
430 440 450 460 470 480
490 500 510 520
pF1KE6 VLALMLLHFRFLPDHTEPRRKLELIMRAEGGLWLRVEPLNVSLQ
::.: ::.:: :::::::::: ::..:::::::::::::.
XP_016 VLGLTLLRFRVLPDHTEPRRKPELVLRAEGGLWLRVEPLS
490 500 510 520
>>NP_001186137 (OMIM: 601270) docosahexaenoic acid omega (520 aa)
initn: 3010 init1: 2986 opt: 2990 Z-score: 3754.9 bits: 704.4 E(85289): 2.1e-202
Smith-Waterman score: 2990; 81.3% identity (92.3% similar) in 520 aa overlap (1-520:1-520)
10 20 30 40 50 60
pF1KE6 MSLLSLPWLGLRPVAMSPWLLLLLVVGSWLLARILAWTYAFYNNCRRLQCFPQPPKRNWF
: ::: ::: :.: ::::::::: .::::::::::::.::.:: ::.:::::::::::
NP_001 MPQLSLSSLGLWPMAASPWLLLLLVGASWLLARILAWTYTFYDNCCRLRCFPQPPKRNWF
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 WGHLGLITPTEEGLKDSTQMSATYSQGFTVWLGPIIPFIVLCHPDTIRSITNASAAIAPK
:::::.::::.:.. ::. ::: ::: ::.:::.: : .:::. :::. ::::::.::
NP_001 LGHLGLVTPTEQGMRVLTQLVATYPQGFKVWMGPIFPVIRFCHPNIIRSVINASAAIVPK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 DNLFIRFLKPWLGEGILLSGGDKWSRHRRMLTPAFHFNILKSYITIFNKSANIMLDKWQH
:..: :::::::.:.:::.:.::::::::::::::::::: :. :::.:.::: :::
NP_001 DKVFYSFLKPWLGDGLLLSAGEKWSRHRRMLTPAFHFNILKPYMKIFNESVNIMHAKWQL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE6 LASEGSSCLDMFEHISLMTLDSLQKCIFSFDSHCQERPSEYIATILELSALVEKRSQHIL
::::::. ::::::::::::::::::.:::::::::.::::::.:::::::: :: :.::
NP_001 LASEGSARLDMFEHISLMTLDSLQKCVFSFDSHCQEKPSEYIAAILELSALVTKRHQQIL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE6 QHMDFLYYLSHDGRRFHRACRLVHDFTDAVIRERRRTLPTQGIDDFFKDKAKSKTLDFID
..::::::. ::.::.::::::::::::::.:::::::.::.:::.. :::::::::::
NP_001 LYIDFLYYLTPDGQRFRRACRLVHDFTDAVIQERRRTLPSQGVDDFLQAKAKSKTLDFID
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE6 VLLLSKDEDGKALSDEDIRAEADTFMFGGHDTTASGLSWVLYNLARHPEYQERCRQEVQE
::::::::::: ::::::::::::::: ::::::::::::::.::.::::::::::::::
NP_001 VLLLSKDEDGKKLSDEDIRAEADTFMFEGHDTTASGLSWVLYHLAKHPEYQERCRQEVQE
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE6 LLKDRDPKEIEWDDLAQLPFLTMCVKESLRLHPPAPFISRCCTQDIVLPDGRVIPKGITC
:::::.::::::::::::::::::.:::::::::.: .:::::::::::::::::::: :
NP_001 LLKDREPKEIEWDDLAQLPFLTMCIKESLRLHPPVPAVSRCCTQDIVLPDGRVIPKGIIC
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE6 LIDIIGVHHNPTVWPDPEVYDPFRFDPENSKGRSPLAFIPFSAGPRNCIGQAFAMAEMKV
::...:.::::.:::::::::::::::.: : ::::::::::::::::::::::::::::
NP_001 LISVFGTHHNPAVWPDPEVYDPFRFDPKNIKERSPLAFIPFSAGPRNCIGQAFAMAEMKV
430 440 450 460 470 480
490 500 510 520
pF1KE6 VLALMLLHFRFLPDHTEPRRKLELIMRAEGGLWLRVEPLNVSLQ
::.: ::.:: :::::::::: ::..:::::::::::::.
NP_001 VLGLTLLRFRVLPDHTEPRRKPELVLRAEGGLWLRVEPLS
490 500 510 520
>>NP_001186138 (OMIM: 601270) docosahexaenoic acid omega (520 aa)
initn: 3010 init1: 2986 opt: 2990 Z-score: 3754.9 bits: 704.4 E(85289): 2.1e-202
Smith-Waterman score: 2990; 81.3% identity (92.3% similar) in 520 aa overlap (1-520:1-520)
10 20 30 40 50 60
pF1KE6 MSLLSLPWLGLRPVAMSPWLLLLLVVGSWLLARILAWTYAFYNNCRRLQCFPQPPKRNWF
: ::: ::: :.: ::::::::: .::::::::::::.::.:: ::.:::::::::::
NP_001 MPQLSLSSLGLWPMAASPWLLLLLVGASWLLARILAWTYTFYDNCCRLRCFPQPPKRNWF
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 WGHLGLITPTEEGLKDSTQMSATYSQGFTVWLGPIIPFIVLCHPDTIRSITNASAAIAPK
:::::.::::.:.. ::. ::: ::: ::.:::.: : .:::. :::. ::::::.::
NP_001 LGHLGLVTPTEQGMRVLTQLVATYPQGFKVWMGPIFPVIRFCHPNIIRSVINASAAIVPK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 DNLFIRFLKPWLGEGILLSGGDKWSRHRRMLTPAFHFNILKSYITIFNKSANIMLDKWQH
:..: :::::::.:.:::.:.::::::::::::::::::: :. :::.:.::: :::
NP_001 DKVFYSFLKPWLGDGLLLSAGEKWSRHRRMLTPAFHFNILKPYMKIFNESVNIMHAKWQL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE6 LASEGSSCLDMFEHISLMTLDSLQKCIFSFDSHCQERPSEYIATILELSALVEKRSQHIL
::::::. ::::::::::::::::::.:::::::::.::::::.:::::::: :: :.::
NP_001 LASEGSARLDMFEHISLMTLDSLQKCVFSFDSHCQEKPSEYIAAILELSALVTKRHQQIL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE6 QHMDFLYYLSHDGRRFHRACRLVHDFTDAVIRERRRTLPTQGIDDFFKDKAKSKTLDFID
..::::::. ::.::.::::::::::::::.:::::::.::.:::.. :::::::::::
NP_001 LYIDFLYYLTPDGQRFRRACRLVHDFTDAVIQERRRTLPSQGVDDFLQAKAKSKTLDFID
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE6 VLLLSKDEDGKALSDEDIRAEADTFMFGGHDTTASGLSWVLYNLARHPEYQERCRQEVQE
::::::::::: ::::::::::::::: ::::::::::::::.::.::::::::::::::
NP_001 VLLLSKDEDGKKLSDEDIRAEADTFMFEGHDTTASGLSWVLYHLAKHPEYQERCRQEVQE
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE6 LLKDRDPKEIEWDDLAQLPFLTMCVKESLRLHPPAPFISRCCTQDIVLPDGRVIPKGITC
:::::.::::::::::::::::::.:::::::::.: .:::::::::::::::::::: :
NP_001 LLKDREPKEIEWDDLAQLPFLTMCIKESLRLHPPVPAVSRCCTQDIVLPDGRVIPKGIIC
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE6 LIDIIGVHHNPTVWPDPEVYDPFRFDPENSKGRSPLAFIPFSAGPRNCIGQAFAMAEMKV
::...:.::::.:::::::::::::::.: : ::::::::::::::::::::::::::::
NP_001 LISVFGTHHNPAVWPDPEVYDPFRFDPKNIKERSPLAFIPFSAGPRNCIGQAFAMAEMKV
430 440 450 460 470 480
490 500 510 520
pF1KE6 VLALMLLHFRFLPDHTEPRRKLELIMRAEGGLWLRVEPLNVSLQ
::.: ::.:: :::::::::: ::..:::::::::::::.
NP_001 VLGLTLLRFRVLPDHTEPRRKPELVLRAEGGLWLRVEPLS
490 500 510 520
>>NP_009184 (OMIM: 611545) cytochrome P450 4F8 precursor (520 aa)
initn: 2879 init1: 2879 opt: 2879 Z-score: 3615.3 bits: 678.6 E(85289): 1.2e-194
Smith-Waterman score: 2879; 78.4% identity (91.1% similar) in 519 aa overlap (1-519:1-519)
10 20 30 40 50 60
pF1KE6 MSLLSLPWLGLRPVAMSPWLLLLLVVGSWLLARILAWTYAFYNNCRRLQCFPQPPKRNWF
:::::: :::::::: :::::::.: .:::::::::::::::.: :::.::::: :.:::
NP_009 MSLLSLSWLGLRPVAASPWLLLLVVGASWLLARILAWTYAFYHNGRRLRCFPQPRKQNWF
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 WGHLGLITPTEEGLKDSTQMSATYSQGFTVWLGPIIPFIVLCHPDTIRSITNASAAIAPK
:::::.:::::::. ::. ::: :::. ::::: :.: ::::: .::. :.: ::. :
NP_009 LGHLGLVTPTEEGLRVLTQLVATYPQGFVRWLGPITPIINLCHPDIVRSVINTSDAITDK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 DNLFIRFLKPWLGEGILLSGGDKWSRHRRMLTPAFHFNILKSYITIFNKSANIMLDKWQH
: .: . ::::::.:.::: :::: .:::.::::::::::: :: ::.:::::: :::.
NP_009 DIVFYKTLKPWLGDGLLLSVGDKWRHHRRLLTPAFHFNILKPYIKIFSKSANIMHAKWQR
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE6 LASEGSSCLDMFEHISLMTLDSLQKCIFSFDSHCQERPSEYIATILELSALVEKRSQHIL
:: :::.:::.:::::::::::::::::::::.:::.:::::..:.:::::: ::.....
NP_009 LAMEGSTCLDVFEHISLMTLDSLQKCIFSFDSNCQEKPSEYITAIMELSALVVKRNNQFF
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE6 QHMDFLYYLSHDGRRFHRACRLVHDFTDAVIRERRRTLPTQGIDDFFKDKAKSKTLDFID
.. ::::.:. :::::::::::::::::::.:::::: .::.:::.. :::::::::::
NP_009 RYKDFLYFLTPCGRRFHRACRLVHDFTDAVIQERRRTLTSQGVDDFLQAKAKSKTLDFID
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE6 VLLLSKDEDGKALSDEDIRAEADTFMFGGHDTTASGLSWVLYNLARHPEYQERCRQEVQE
:::::.:..:: ::::::::::::::::::::::::::::::::::::::::::::::::
NP_009 VLLLSEDKNGKELSDEDIRAEADTFMFGGHDTTASGLSWVLYNLARHPEYQERCRQEVQE
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE6 LLKDRDPKEIEWDDLAQLPFLTMCVKESLRLHPPAPFISRCCTQDIVLPDGRVIPKGITC
:::::.::::::::::::::::::.::::::::: : ..: ::::.::::.:::::: .:
NP_009 LLKDREPKEIEWDDLAQLPFLTMCLKESLRLHPPIPTFARGCTQDVVLPDSRVIPKGNVC
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE6 LIDIIGVHHNPTVWPDPEVYDPFRFDPENSKGRSPLAFIPFSAGPRNCIGQAFAMAEMKV
:.:...::::.:::::::::::::::::.. :::.::::::::::::::: ::::::::
NP_009 NINIFAIHHNPSVWPDPEVYDPFRFDPENAQKRSPMAFIPFSAGPRNCIGQKFAMAEMKV
430 440 450 460 470 480
490 500 510 520
pF1KE6 VLALMLLHFRFLPDHTEPRRKLELIMRAEGGLWLRVEPLNVSLQ
:::: ::.::.:::: :::: :...::: :::::::::
NP_009 VLALTLLRFRILPDHREPRRTPEIVLRAEDGLWLRVEPLG
490 500 510 520
>>NP_000887 (OMIM: 601270) docosahexaenoic acid omega-hy (520 aa)
initn: 2871 init1: 2847 opt: 2851 Z-score: 3580.1 bits: 672.1 E(85289): 1.1e-192
Smith-Waterman score: 2851; 78.3% identity (90.0% similar) in 520 aa overlap (1-520:1-520)
10 20 30 40 50 60
pF1KE6 MSLLSLPWLGLRPVAMSPWLLLLLVVGSWLLARILAWTYAFYNNCRRLQCFPQPPKRNWF
: ::: ::: :.: ::::::::: .::::::::::::.::.:: ::.:::::::::::
NP_000 MPQLSLSSLGLWPMAASPWLLLLLVGASWLLARILAWTYTFYDNCCRLRCFPQPPKRNWF
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 WGHLGLITPTEEGLKDSTQMSATYSQGFTVWLGPIIPFIVLCHPDTIRSITNASAAIAPK
:::::: .:::: . ... :... :.:: .. . :: :. . : :::.::
NP_000 LGHLGLIHSSEEGLLYTQSLACTFGDMCCWWVGPWHAIVRIFHPTYIKPVLFAPAAIVPK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 DNLFIRFLKPWLGEGILLSGGDKWSRHRRMLTPAFHFNILKSYITIFNKSANIMLDKWQH
:..: :::::::.:.:::.:.::::::::::::::::::: :. :::.:.::: :::
NP_000 DKVFYSFLKPWLGDGLLLSAGEKWSRHRRMLTPAFHFNILKPYMKIFNESVNIMHAKWQL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE6 LASEGSSCLDMFEHISLMTLDSLQKCIFSFDSHCQERPSEYIATILELSALVEKRSQHIL
::::::. ::::::::::::::::::.:::::::::.::::::.:::::::: :: :.::
NP_000 LASEGSARLDMFEHISLMTLDSLQKCVFSFDSHCQEKPSEYIAAILELSALVTKRHQQIL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE6 QHMDFLYYLSHDGRRFHRACRLVHDFTDAVIRERRRTLPTQGIDDFFKDKAKSKTLDFID
..::::::. ::.::.::::::::::::::.:::::::.::.:::.. :::::::::::
NP_000 LYIDFLYYLTPDGQRFRRACRLVHDFTDAVIQERRRTLPSQGVDDFLQAKAKSKTLDFID
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE6 VLLLSKDEDGKALSDEDIRAEADTFMFGGHDTTASGLSWVLYNLARHPEYQERCRQEVQE
::::::::::: ::::::::::::::: ::::::::::::::.::.::::::::::::::
NP_000 VLLLSKDEDGKKLSDEDIRAEADTFMFEGHDTTASGLSWVLYHLAKHPEYQERCRQEVQE
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE6 LLKDRDPKEIEWDDLAQLPFLTMCVKESLRLHPPAPFISRCCTQDIVLPDGRVIPKGITC
:::::.::::::::::::::::::.:::::::::.: .:::::::::::::::::::: :
NP_000 LLKDREPKEIEWDDLAQLPFLTMCIKESLRLHPPVPAVSRCCTQDIVLPDGRVIPKGIIC
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE6 LIDIIGVHHNPTVWPDPEVYDPFRFDPENSKGRSPLAFIPFSAGPRNCIGQAFAMAEMKV
::...:.::::.:::::::::::::::.: : ::::::::::::::::::::::::::::
NP_000 LISVFGTHHNPAVWPDPEVYDPFRFDPKNIKERSPLAFIPFSAGPRNCIGQAFAMAEMKV
430 440 450 460 470 480
490 500 510 520
pF1KE6 VLALMLLHFRFLPDHTEPRRKLELIMRAEGGLWLRVEPLNVSLQ
::.: ::.:: :::::::::: ::..:::::::::::::.
NP_000 VLGLTLLRFRVLPDHTEPRRKPELVLRAEGGLWLRVEPLS
490 500 510 520
>>XP_006722913 (OMIM: 611485) PREDICTED: cytochrome P450 (375 aa)
initn: 2561 init1: 2561 opt: 2561 Z-score: 3217.5 bits: 604.5 E(85289): 1.8e-172
Smith-Waterman score: 2561; 99.7% identity (99.7% similar) in 375 aa overlap (150-524:1-375)
120 130 140 150 160 170
pF1KE6 KDNLFIRFLKPWLGEGILLSGGDKWSRHRRMLTPAFHFNILKSYITIFNKSANIMLDKWQ
::::::::::::::::::::::::::::::
XP_006 MLTPAFHFNILKSYITIFNKSANIMLDKWQ
10 20 30
180 190 200 210 220 230
pF1KE6 HLASEGSSCLDMFEHISLMTLDSLQKCIFSFDSHCQERPSEYIATILELSALVEKRSQHI
:::::::: :::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 HLASEGSSRLDMFEHISLMTLDSLQKCIFSFDSHCQERPSEYIATILELSALVEKRSQHI
40 50 60 70 80 90
240 250 260 270 280 290
pF1KE6 LQHMDFLYYLSHDGRRFHRACRLVHDFTDAVIRERRRTLPTQGIDDFFKDKAKSKTLDFI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 LQHMDFLYYLSHDGRRFHRACRLVHDFTDAVIRERRRTLPTQGIDDFFKDKAKSKTLDFI
100 110 120 130 140 150
300 310 320 330 340 350
pF1KE6 DVLLLSKDEDGKALSDEDIRAEADTFMFGGHDTTASGLSWVLYNLARHPEYQERCRQEVQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 DVLLLSKDEDGKALSDEDIRAEADTFMFGGHDTTASGLSWVLYNLARHPEYQERCRQEVQ
160 170 180 190 200 210
360 370 380 390 400 410
pF1KE6 ELLKDRDPKEIEWDDLAQLPFLTMCVKESLRLHPPAPFISRCCTQDIVLPDGRVIPKGIT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 ELLKDRDPKEIEWDDLAQLPFLTMCVKESLRLHPPAPFISRCCTQDIVLPDGRVIPKGIT
220 230 240 250 260 270
420 430 440 450 460 470
pF1KE6 CLIDIIGVHHNPTVWPDPEVYDPFRFDPENSKGRSPLAFIPFSAGPRNCIGQAFAMAEMK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 CLIDIIGVHHNPTVWPDPEVYDPFRFDPENSKGRSPLAFIPFSAGPRNCIGQAFAMAEMK
280 290 300 310 320 330
480 490 500 510 520
pF1KE6 VVLALMLLHFRFLPDHTEPRRKLELIMRAEGGLWLRVEPLNVSLQ
:::::::::::::::::::::::::::::::::::::::::::::
XP_006 VVLALMLLHFRFLPDHTEPRRKLELIMRAEGGLWLRVEPLNVSLQ
340 350 360 370
524 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Nov 8 13:10:39 2016 done: Tue Nov 8 13:10:40 2016
Total Scan time: 5.800 Total Display time: 0.060
Function used was FASTA [36.3.4 Apr, 2011]