Result of FASTA (omim) for
pFN21AE6419
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE6419, 496 aa
1>>>pF1KE6419 496 - 496 aa - 496 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 4.8804+/-0.00044; mu= 20.3773+/- 0.027
mean_var=61.2191+/-12.516, 0's: 0 Z-trim(111.6): 26 B-trim: 1207 in 2/47
Lambda= 0.163920
statistics sampled from 20209 (20235) to 20209 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.6), E-opt: 0.2 (0.237), width: 16
Scan time: 6.440
The best scores are: opt bits E(85289)
NP_005031 (OMIM: 176785) lysosomal Pro-X carboxype ( 496) 3420 817.6 0
NP_955450 (OMIM: 176785) lysosomal Pro-X carboxype ( 517) 3062 733.0 5e-211
XP_005274150 (OMIM: 176785) PREDICTED: lysosomal P ( 391) 2709 649.4 5.3e-186
NP_001306143 (OMIM: 176785) lysosomal Pro-X carbox ( 391) 2709 649.4 5.3e-186
NP_037511 (OMIM: 610537) dipeptidyl peptidase 2 pr ( 492) 1259 306.6 1.1e-82
XP_011516902 (OMIM: 610537) PREDICTED: dipeptidyl ( 484) 1134 277.0 8.4e-74
XP_011516901 (OMIM: 610537) PREDICTED: dipeptidyl ( 514) 1134 277.0 8.8e-74
XP_016870141 (OMIM: 610537) PREDICTED: dipeptidyl ( 436) 953 234.2 5.9e-61
XP_016870140 (OMIM: 610537) PREDICTED: dipeptidyl ( 458) 828 204.6 4.9e-52
XP_005266132 (OMIM: 610537) PREDICTED: dipeptidyl ( 565) 771 191.2 6.6e-48
XP_006717146 (OMIM: 610537) PREDICTED: dipeptidyl ( 509) 465 118.8 3.7e-26
XP_016865651 (OMIM: 607169) PREDICTED: thymus-spec ( 454) 410 105.8 2.8e-22
NP_005856 (OMIM: 607169) thymus-specific serine pr ( 514) 410 105.8 3.1e-22
XP_016865653 (OMIM: 607169) PREDICTED: thymus-spec ( 357) 347 90.8 7e-18
XP_016865652 (OMIM: 607169) PREDICTED: thymus-spec ( 417) 347 90.8 7.9e-18
XP_016865650 (OMIM: 607169) PREDICTED: thymus-spec ( 488) 283 75.8 3.2e-13
XP_016865654 (OMIM: 607169) PREDICTED: thymus-spec ( 257) 201 56.2 1.3e-07
>>NP_005031 (OMIM: 176785) lysosomal Pro-X carboxypeptid (496 aa)
initn: 3420 init1: 3420 opt: 3420 Z-score: 4367.5 bits: 817.6 E(85289): 0
Smith-Waterman score: 3420; 100.0% identity (100.0% similar) in 496 aa overlap (1-496:1-496)
10 20 30 40 50 60
pF1KE6 MGRRALLLLLLSFLAPWATIALRPALRALGSLHLPTNPTSLPAVAKNYSVLYFQQKVDHF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 MGRRALLLLLLSFLAPWATIALRPALRALGSLHLPTNPTSLPAVAKNYSVLYFQQKVDHF
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 GFNTVKTFNQRYLVADKYWKKNGGSILFYTGNEGDIIWFCNNTGFMWDVAEELKAMLVFA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 GFNTVKTFNQRYLVADKYWKKNGGSILFYTGNEGDIIWFCNNTGFMWDVAEELKAMLVFA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 EHRYYGESLPFGDNSFKDSRHLNFLTSEQALADFAELIKHLKRTIPGAENQPVIAIGGSY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 EHRYYGESLPFGDNSFKDSRHLNFLTSEQALADFAELIKHLKRTIPGAENQPVIAIGGSY
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE6 GGMLAAWFRMKYPHMVVGALAASAPIWQFEDLVPCGVFMKIVTTDFRKSGPHCSESIHRS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 GGMLAAWFRMKYPHMVVGALAASAPIWQFEDLVPCGVFMKIVTTDFRKSGPHCSESIHRS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE6 WDAINRLSNTGSGLQWLTGALHLCSPLTSQDIQHLKDWISETWVNLAMVDYPYASNFLQP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 WDAINRLSNTGSGLQWLTGALHLCSPLTSQDIQHLKDWISETWVNLAMVDYPYASNFLQP
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE6 LPAWPIKVVCQYLKNPNVSDSLLLQNIFQALNVYYNYSGQVKCLNISETATSSLGTLGWS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 LPAWPIKVVCQYLKNPNVSDSLLLQNIFQALNVYYNYSGQVKCLNISETATSSLGTLGWS
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE6 YQACTEVVMPFCTNGVDDMFEPHSWNLKELSDDCFQQWGVRPRPSWITTMYGGKNISSHT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 YQACTEVVMPFCTNGVDDMFEPHSWNLKELSDDCFQQWGVRPRPSWITTMYGGKNISSHT
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE6 NIVFSNGELDPWSGGGVTKDITDTLVAVTISEGAHHLDLRTKNALDPMSVLLARSLEVRH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_005 NIVFSNGELDPWSGGGVTKDITDTLVAVTISEGAHHLDLRTKNALDPMSVLLARSLEVRH
430 440 450 460 470 480
490
pF1KE6 MKNWIRDFYDSAGKQH
::::::::::::::::
NP_005 MKNWIRDFYDSAGKQH
490
>>NP_955450 (OMIM: 176785) lysosomal Pro-X carboxypeptid (517 aa)
initn: 3406 init1: 3062 opt: 3062 Z-score: 3909.7 bits: 733.0 E(85289): 5e-211
Smith-Waterman score: 3368; 95.9% identity (95.9% similar) in 517 aa overlap (1-496:1-517)
10 20 30 40 50
pF1KE6 MGRRALLLLLLSFLAPWATIALRPALRALGSLHLPTNPTSLPAVAKNYSVLYFQQK----
::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_955 MGRRALLLLLLSFLAPWATIALRPALRALGSLHLPTNPTSLPAVAKNYSVLYFQQKALAA
10 20 30 40 50 60
60 70 80 90
pF1KE6 -----------------VDHFGFNTVKTFNQRYLVADKYWKKNGGSILFYTGNEGDIIWF
:::::::::::::::::::::::::::::::::::::::::::
NP_955 GQLHICIIQLNHYKTPLVDHFGFNTVKTFNQRYLVADKYWKKNGGSILFYTGNEGDIIWF
70 80 90 100 110 120
100 110 120 130 140 150
pF1KE6 CNNTGFMWDVAEELKAMLVFAEHRYYGESLPFGDNSFKDSRHLNFLTSEQALADFAELIK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_955 CNNTGFMWDVAEELKAMLVFAEHRYYGESLPFGDNSFKDSRHLNFLTSEQALADFAELIK
130 140 150 160 170 180
160 170 180 190 200 210
pF1KE6 HLKRTIPGAENQPVIAIGGSYGGMLAAWFRMKYPHMVVGALAASAPIWQFEDLVPCGVFM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_955 HLKRTIPGAENQPVIAIGGSYGGMLAAWFRMKYPHMVVGALAASAPIWQFEDLVPCGVFM
190 200 210 220 230 240
220 230 240 250 260 270
pF1KE6 KIVTTDFRKSGPHCSESIHRSWDAINRLSNTGSGLQWLTGALHLCSPLTSQDIQHLKDWI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_955 KIVTTDFRKSGPHCSESIHRSWDAINRLSNTGSGLQWLTGALHLCSPLTSQDIQHLKDWI
250 260 270 280 290 300
280 290 300 310 320 330
pF1KE6 SETWVNLAMVDYPYASNFLQPLPAWPIKVVCQYLKNPNVSDSLLLQNIFQALNVYYNYSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_955 SETWVNLAMVDYPYASNFLQPLPAWPIKVVCQYLKNPNVSDSLLLQNIFQALNVYYNYSG
310 320 330 340 350 360
340 350 360 370 380 390
pF1KE6 QVKCLNISETATSSLGTLGWSYQACTEVVMPFCTNGVDDMFEPHSWNLKELSDDCFQQWG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_955 QVKCLNISETATSSLGTLGWSYQACTEVVMPFCTNGVDDMFEPHSWNLKELSDDCFQQWG
370 380 390 400 410 420
400 410 420 430 440 450
pF1KE6 VRPRPSWITTMYGGKNISSHTNIVFSNGELDPWSGGGVTKDITDTLVAVTISEGAHHLDL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_955 VRPRPSWITTMYGGKNISSHTNIVFSNGELDPWSGGGVTKDITDTLVAVTISEGAHHLDL
430 440 450 460 470 480
460 470 480 490
pF1KE6 RTKNALDPMSVLLARSLEVRHMKNWIRDFYDSAGKQH
:::::::::::::::::::::::::::::::::::::
NP_955 RTKNALDPMSVLLARSLEVRHMKNWIRDFYDSAGKQH
490 500 510
>>XP_005274150 (OMIM: 176785) PREDICTED: lysosomal Pro-X (391 aa)
initn: 2709 init1: 2709 opt: 2709 Z-score: 3460.2 bits: 649.4 E(85289): 5.3e-186
Smith-Waterman score: 2709; 100.0% identity (100.0% similar) in 391 aa overlap (106-496:1-391)
80 90 100 110 120 130
pF1KE6 DKYWKKNGGSILFYTGNEGDIIWFCNNTGFMWDVAEELKAMLVFAEHRYYGESLPFGDNS
::::::::::::::::::::::::::::::
XP_005 MWDVAEELKAMLVFAEHRYYGESLPFGDNS
10 20 30
140 150 160 170 180 190
pF1KE6 FKDSRHLNFLTSEQALADFAELIKHLKRTIPGAENQPVIAIGGSYGGMLAAWFRMKYPHM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 FKDSRHLNFLTSEQALADFAELIKHLKRTIPGAENQPVIAIGGSYGGMLAAWFRMKYPHM
40 50 60 70 80 90
200 210 220 230 240 250
pF1KE6 VVGALAASAPIWQFEDLVPCGVFMKIVTTDFRKSGPHCSESIHRSWDAINRLSNTGSGLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VVGALAASAPIWQFEDLVPCGVFMKIVTTDFRKSGPHCSESIHRSWDAINRLSNTGSGLQ
100 110 120 130 140 150
260 270 280 290 300 310
pF1KE6 WLTGALHLCSPLTSQDIQHLKDWISETWVNLAMVDYPYASNFLQPLPAWPIKVVCQYLKN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 WLTGALHLCSPLTSQDIQHLKDWISETWVNLAMVDYPYASNFLQPLPAWPIKVVCQYLKN
160 170 180 190 200 210
320 330 340 350 360 370
pF1KE6 PNVSDSLLLQNIFQALNVYYNYSGQVKCLNISETATSSLGTLGWSYQACTEVVMPFCTNG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 PNVSDSLLLQNIFQALNVYYNYSGQVKCLNISETATSSLGTLGWSYQACTEVVMPFCTNG
220 230 240 250 260 270
380 390 400 410 420 430
pF1KE6 VDDMFEPHSWNLKELSDDCFQQWGVRPRPSWITTMYGGKNISSHTNIVFSNGELDPWSGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 VDDMFEPHSWNLKELSDDCFQQWGVRPRPSWITTMYGGKNISSHTNIVFSNGELDPWSGG
280 290 300 310 320 330
440 450 460 470 480 490
pF1KE6 GVTKDITDTLVAVTISEGAHHLDLRTKNALDPMSVLLARSLEVRHMKNWIRDFYDSAGKQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GVTKDITDTLVAVTISEGAHHLDLRTKNALDPMSVLLARSLEVRHMKNWIRDFYDSAGKQ
340 350 360 370 380 390
pF1KE6 H
:
XP_005 H
>>NP_001306143 (OMIM: 176785) lysosomal Pro-X carboxypep (391 aa)
initn: 2709 init1: 2709 opt: 2709 Z-score: 3460.2 bits: 649.4 E(85289): 5.3e-186
Smith-Waterman score: 2709; 100.0% identity (100.0% similar) in 391 aa overlap (106-496:1-391)
80 90 100 110 120 130
pF1KE6 DKYWKKNGGSILFYTGNEGDIIWFCNNTGFMWDVAEELKAMLVFAEHRYYGESLPFGDNS
::::::::::::::::::::::::::::::
NP_001 MWDVAEELKAMLVFAEHRYYGESLPFGDNS
10 20 30
140 150 160 170 180 190
pF1KE6 FKDSRHLNFLTSEQALADFAELIKHLKRTIPGAENQPVIAIGGSYGGMLAAWFRMKYPHM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FKDSRHLNFLTSEQALADFAELIKHLKRTIPGAENQPVIAIGGSYGGMLAAWFRMKYPHM
40 50 60 70 80 90
200 210 220 230 240 250
pF1KE6 VVGALAASAPIWQFEDLVPCGVFMKIVTTDFRKSGPHCSESIHRSWDAINRLSNTGSGLQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VVGALAASAPIWQFEDLVPCGVFMKIVTTDFRKSGPHCSESIHRSWDAINRLSNTGSGLQ
100 110 120 130 140 150
260 270 280 290 300 310
pF1KE6 WLTGALHLCSPLTSQDIQHLKDWISETWVNLAMVDYPYASNFLQPLPAWPIKVVCQYLKN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 WLTGALHLCSPLTSQDIQHLKDWISETWVNLAMVDYPYASNFLQPLPAWPIKVVCQYLKN
160 170 180 190 200 210
320 330 340 350 360 370
pF1KE6 PNVSDSLLLQNIFQALNVYYNYSGQVKCLNISETATSSLGTLGWSYQACTEVVMPFCTNG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PNVSDSLLLQNIFQALNVYYNYSGQVKCLNISETATSSLGTLGWSYQACTEVVMPFCTNG
220 230 240 250 260 270
380 390 400 410 420 430
pF1KE6 VDDMFEPHSWNLKELSDDCFQQWGVRPRPSWITTMYGGKNISSHTNIVFSNGELDPWSGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VDDMFEPHSWNLKELSDDCFQQWGVRPRPSWITTMYGGKNISSHTNIVFSNGELDPWSGG
280 290 300 310 320 330
440 450 460 470 480 490
pF1KE6 GVTKDITDTLVAVTISEGAHHLDLRTKNALDPMSVLLARSLEVRHMKNWIRDFYDSAGKQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GVTKDITDTLVAVTISEGAHHLDLRTKNALDPMSVLLARSLEVRHMKNWIRDFYDSAGKQ
340 350 360 370 380 390
pF1KE6 H
:
NP_001 H
>>NP_037511 (OMIM: 610537) dipeptidyl peptidase 2 prepro (492 aa)
initn: 1202 init1: 425 opt: 1259 Z-score: 1605.6 bits: 306.6 E(85289): 1.1e-82
Smith-Waterman score: 1286; 42.4% identity (69.9% similar) in 488 aa overlap (15-486:4-474)
10 20 30 40 50 60
pF1KE6 MGRRALLLLLLSFLAPWATIALRPALRALGSLHLPTNPTSLPAVAKNYSVLYFQQKVDHF
:::: . : ::: : .. : ... .:::..:::
NP_037 MGSAPWAPVLLL----ALGLRGLQAGARRAPD--PGFQERFFQQRLDHF
10 20 30 40
70 80 90 100 110
pF1KE6 GFNTV--KTFNQRYLVADKYWKKNGGSILFYTGNEGDIIWFCNNTGFMWDVAEELKAMLV
.:. ::: ::.::.:..: .. : :.::::::::. : ::..:. ..: : :.::
NP_037 NFERFGNKTFPQRFLVSDRFWVRGEGPIFFYTGNEGDVWAFANNSAFVAELAAERGALLV
50 60 70 80 90 100
120 130 140 150 160 170
pF1KE6 FAEHRYYGESLPFGDNSFKDSRHLNFLTSEQALADFAELIKHLKRTIPGAENQPVIAIGG
::::::::.::::: .: . . : ..:: ::::::::::.. :.: . ::.. :.::.::
NP_037 FAEHRYYGKSLPFGAQSTQRG-HTELLTVEQALADFAELLRALRRDL-GAQDAPAIAFGG
110 120 130 140 150 160
180 190 200 210 220 230
pF1KE6 SYGGMLAAWFRMKYPHMVVGALAASAPIWQFEDLVPCGVFMKIVTTDFRKSGPHCSESIH
::::::.:..::::::.:.::::::::. : . :.. ::.::. ..:.:.....
NP_037 SYGGMLSAYLRMKYPHLVAGALAASAPVLAVAGLGDSNQFFRDVTADFEGQSPKCTQGVR
170 180 190 200 210 220
240 250 260 270 280 290
pF1KE6 RSWDAINRLSNTGS--GLQWLTGALHLCSPLTSQ-DIQHLKDWISETWVNLAMVDYPYAS
... :. : :. ..: :. :.::... :. .: . .... :::.:::: .
NP_037 EAFRQIKDLFLQGAYDTVRWEFGT---CQPLSDEKDLTQLFMFARNAFTVLAMMDYPYPT
230 240 250 260 270
300 310 320 330 340 350
pF1KE6 NFLQPLPAWPIKVVCQYLKNPNVSDSLLLQNIFQALNVYYNYSGQVKCLNISETATSSLG
.:: :::: :.:: :. : .:.. . .. .. :: ::. .: .: . :
NP_037 DFLGPLPANPVKVGCDRL----LSEAQRITGLRALAGLVYNASGSEHCYDIYRLYHSCAD
280 290 300 310 320 330
360 370 380 390 400
pF1KE6 TLG---------WSYQACTEVVMPFCTNGVDDMFE--PHSWNLKELSDDCFQQWGVRPRP
: :.::::::. . : .:.: ::: : . .:.. :.. ::: :::
NP_037 PTGCGTGPDARAWDYQACTEINLTFASNNVTDMFPDLPFTDELRQRY--CLDTWGVWPRP
340 350 360 370 380 390
410 420 430 440 450 460
pF1KE6 SWITTMYGGKNISSHTNIVFSNGELDPWSGGGVTKDITDTLVAVTISEGAHHLDLRTKNA
.:. : . : .. . .::.::::.::::.:::. .... ...::::. ::::::::...
NP_037 DWLLTSFWGGDLRAASNIIFSNGNLDPWAGGGIRRNLSASVIAVTIQGGAHHLDLRASHP
400 410 420 430 440 450
470 480 490
pF1KE6 LDPMSVLLARSLEVRHMKNWIRDFYDSAGKQH
:: ::. ::.::. . .:..
NP_037 EDPASVVEARKLEATIIGEWVKAARREQQPALRGGPRLSL
460 470 480 490
>>XP_011516902 (OMIM: 610537) PREDICTED: dipeptidyl pept (484 aa)
initn: 1072 init1: 425 opt: 1134 Z-score: 1445.9 bits: 277.0 E(85289): 8.4e-74
Smith-Waterman score: 1161; 43.0% identity (71.4% similar) in 423 aa overlap (78-486:55-466)
50 60 70 80 90 100
pF1KE6 YSVLYFQQKVDHFGFNTVKTFNQRYLVADKYWKKNGGSILFYTGNEGDIIWFCNNTGFMW
.: .. : :.::::::::. : ::..:.
XP_011 PGALLPAASGPLQLRALRQQDLPSALPGVGFWVRGEGPIFFYTGNEGDVWAFANNSAFVA
30 40 50 60 70 80
110 120 130 140 150 160
pF1KE6 DVAEELKAMLVFAEHRYYGESLPFGDNSFKDSRHLNFLTSEQALADFAELIKHLKRTIPG
..: : :.::::::::::.::::: .: . . : ..:: ::::::::::.. :.: . :
XP_011 ELAAERGALLVFAEHRYYGKSLPFGAQSTQRG-HTELLTVEQALADFAELLRALRRDL-G
90 100 110 120 130 140
170 180 190 200 210 220
pF1KE6 AENQPVIAIGGSYGGMLAAWFRMKYPHMVVGALAASAPIWQFEDLVPCGVFMKIVTTDFR
:.. :.::.::::::::.:..::::::.:.::::::::. : . :.. ::.::.
XP_011 AQDAPAIAFGGSYGGMLSAYLRMKYPHLVAGALAASAPVLAVAGLGDSNQFFRDVTADFE
150 160 170 180 190 200
230 240 250 260 270 280
pF1KE6 KSGPHCSESIHRSWDAINRLSNTGS--GLQWLTGALHLCSPLTSQ-DIQHLKDWISETWV
..:.:........ :. : :. ..: :. :.::... :. .: . ....
XP_011 GQSPKCTQGVREAFRQIKDLFLQGAYDTVRWEFGT---CQPLSDEKDLTQLFMFARNAFT
210 220 230 240 250
290 300 310 320 330 340
pF1KE6 NLAMVDYPYASNFLQPLPAWPIKVVCQYLKNPNVSDSLLLQNIFQALNVYYNYSGQVKCL
:::.:::: ..:: :::: :.:: :. : .:.. . .. .. :: ::. .:
XP_011 VLAMMDYPYPTDFLGPLPANPVKVGCDRL----LSEAQRITGLRALAGLVYNASGSEHCY
260 270 280 290 300 310
350 360 370 380 390
pF1KE6 NISETATSSLGTLG---------WSYQACTEVVMPFCTNGVDDMFE--PHSWNLKELSDD
.: . : : :.::::::. . : .:.: ::: : . .:..
XP_011 DIYRLYHSCADPTGCGTGPDARAWDYQACTEINLTFASNNVTDMFPDLPFTDELRQ--RY
320 330 340 350 360 370
400 410 420 430 440 450
pF1KE6 CFQQWGVRPRPSWITTMYGGKNISSHTNIVFSNGELDPWSGGGVTKDITDTLVAVTISEG
:.. ::: :::.:. : . : .. . .::.::::.::::.:::. .... ...::::. :
XP_011 CLDTWGVWPRPDWLLTSFWGGDLRAASNIIFSNGNLDPWAGGGIRRNLSASVIAVTIQGG
380 390 400 410 420 430
460 470 480 490
pF1KE6 AHHLDLRTKNALDPMSVLLARSLEVRHMKNWIRDFYDSAGKQH
:::::::... :: ::. ::.::. . .:..
XP_011 AHHLDLRASHPEDPASVVEARKLEATIIGEWVKAARREQQPALRGGPRLSL
440 450 460 470 480
>>XP_011516901 (OMIM: 610537) PREDICTED: dipeptidyl pept (514 aa)
initn: 1099 init1: 425 opt: 1134 Z-score: 1445.6 bits: 277.0 E(85289): 8.8e-74
Smith-Waterman score: 1161; 43.0% identity (71.4% similar) in 423 aa overlap (78-486:85-496)
50 60 70 80 90 100
pF1KE6 YSVLYFQQKVDHFGFNTVKTFNQRYLVADKYWKKNGGSILFYTGNEGDIIWFCNNTGFMW
.: .. : :.::::::::. : ::..:.
XP_011 PGALLPAASGPLQLRALRQQDLPSALPGVGFWVRGEGPIFFYTGNEGDVWAFANNSAFVA
60 70 80 90 100 110
110 120 130 140 150 160
pF1KE6 DVAEELKAMLVFAEHRYYGESLPFGDNSFKDSRHLNFLTSEQALADFAELIKHLKRTIPG
..: : :.::::::::::.::::: .: . . : ..:: ::::::::::.. :.: . :
XP_011 ELAAERGALLVFAEHRYYGKSLPFGAQSTQRG-HTELLTVEQALADFAELLRALRRDL-G
120 130 140 150 160 170
170 180 190 200 210 220
pF1KE6 AENQPVIAIGGSYGGMLAAWFRMKYPHMVVGALAASAPIWQFEDLVPCGVFMKIVTTDFR
:.. :.::.::::::::.:..::::::.:.::::::::. : . :.. ::.::.
XP_011 AQDAPAIAFGGSYGGMLSAYLRMKYPHLVAGALAASAPVLAVAGLGDSNQFFRDVTADFE
180 190 200 210 220 230
230 240 250 260 270 280
pF1KE6 KSGPHCSESIHRSWDAINRLSNTGS--GLQWLTGALHLCSPLTSQ-DIQHLKDWISETWV
..:.:........ :. : :. ..: :. :.::... :. .: . ....
XP_011 GQSPKCTQGVREAFRQIKDLFLQGAYDTVRWEFGT---CQPLSDEKDLTQLFMFARNAFT
240 250 260 270 280
290 300 310 320 330 340
pF1KE6 NLAMVDYPYASNFLQPLPAWPIKVVCQYLKNPNVSDSLLLQNIFQALNVYYNYSGQVKCL
:::.:::: ..:: :::: :.:: :. : .:.. . .. .. :: ::. .:
XP_011 VLAMMDYPYPTDFLGPLPANPVKVGCDRL----LSEAQRITGLRALAGLVYNASGSEHCY
290 300 310 320 330 340
350 360 370 380 390
pF1KE6 NISETATSSLGTLG---------WSYQACTEVVMPFCTNGVDDMFE--PHSWNLKELSDD
.: . : : :.::::::. . : .:.: ::: : . .:..
XP_011 DIYRLYHSCADPTGCGTGPDARAWDYQACTEINLTFASNNVTDMFPDLPFTDELRQ--RY
350 360 370 380 390 400
400 410 420 430 440 450
pF1KE6 CFQQWGVRPRPSWITTMYGGKNISSHTNIVFSNGELDPWSGGGVTKDITDTLVAVTISEG
:.. ::: :::.:. : . : .. . .::.::::.::::.:::. .... ...::::. :
XP_011 CLDTWGVWPRPDWLLTSFWGGDLRAASNIIFSNGNLDPWAGGGIRRNLSASVIAVTIQGG
410 420 430 440 450 460
460 470 480 490
pF1KE6 AHHLDLRTKNALDPMSVLLARSLEVRHMKNWIRDFYDSAGKQH
:::::::... :: ::. ::.::. . .:..
XP_011 AHHLDLRASHPEDPASVVEARKLEATIIGEWVKAARREQQPALRGGPRLSL
470 480 490 500 510
>>XP_016870141 (OMIM: 610537) PREDICTED: dipeptidyl pept (436 aa)
initn: 882 init1: 362 opt: 953 Z-score: 1215.3 bits: 234.2 E(85289): 5.9e-61
Smith-Waterman score: 953; 40.9% identity (67.7% similar) in 406 aa overlap (15-404:4-394)
10 20 30 40 50 60
pF1KE6 MGRRALLLLLLSFLAPWATIALRPALRALGSLHLPTNPTSLPAVAKNYSVLYFQQKVDHF
:::: . : ::: : .. : ... .:::..:::
XP_016 MGSAPWAPVLL----LALGLRGLQAGARRAP--DPGFQERFFQQRLDHF
10 20 30 40
70 80 90 100 110
pF1KE6 GFNTV--KTFNQRYLVADKYWKKNGGSILFYTGNEGDIIWFCNNTGFMWDVAEELKAMLV
.:. ::: ::.::.:..: .. : :.::::::::. : ::..:. ..: : :.::
XP_016 NFERFGNKTFPQRFLVSDRFWVRGEGPIFFYTGNEGDVWAFANNSAFVAELAAERGALLV
50 60 70 80 90 100
120 130 140 150 160 170
pF1KE6 FAEHRYYGESLPFGDNSFKDSRHLNFLTSEQALADFAELIKHLKRTIPGAENQPVIAIGG
::::::::.::::: .: . . : ..:: ::::::::::.. :.: . ::.. :.::.::
XP_016 FAEHRYYGKSLPFGAQSTQRG-HTELLTVEQALADFAELLRALRRDL-GAQDAPAIAFGG
110 120 130 140 150 160
180 190 200 210 220 230
pF1KE6 SYGGMLAAWFRMKYPHMVVGALAASAPIWQFEDLVPCGVFMKIVTTDFRKSGPHCSESIH
::::::.:..::::::.:.::::::::. : . :.. ::.::. ..:.:.....
XP_016 SYGGMLSAYLRMKYPHLVAGALAASAPVLAVAGLGDSNQFFRDVTADFEGQSPKCTQGVR
170 180 190 200 210 220
240 250 260 270 280 290
pF1KE6 RSWDAINRLSNTGS--GLQWLTGALHLCSPLTSQ-DIQHLKDWISETWVNLAMVDYPYAS
... :. : :. ..: :. :.::... :. .: . .... :::.:::: .
XP_016 EAFRQIKDLFLQGAYDTVRWEFGT---CQPLSDEKDLTQLFMFARNAFTVLAMMDYPYPT
230 240 250 260 270
300 310 320 330 340 350
pF1KE6 NFLQPLPAWPIKVVCQYLKNPNVSDSLLLQNIFQALNVYYNYSGQVKCLNISETATSSLG
.:: :::: :.:: :. : .:.. . .. .. :: ::. .: .: . :
XP_016 DFLGPLPANPVKVGCDRL----LSEAQRITGLRALAGLVYNASGSEHCYDIYRLYHSCAD
280 290 300 310 320 330
360 370 380 390 400
pF1KE6 TLG---------WSYQACTEVVMPFCTNGVDDMFE--PHSWNLKELSDDCFQQWGVRPRP
: :.::::::. . : .:.: ::: : . .:.. :.. :. .. .:
XP_016 PTGCGTGPDARAWDYQACTEINLTFASNNVTDMFPDLPFTDELRQRSQSRQQHHLLQREP
340 350 360 370 380 390
410 420 430 440 450 460
pF1KE6 SWITTMYGGKNISSHTNIVFSNGELDPWSGGGVTKDITDTLVAVTISEGAHHLDLRTKNA
XP_016 GPLGRGRDSEEPECLSHRRHHPGGSAPPRPQSLPPRRSCFRG
400 410 420 430
>>XP_016870140 (OMIM: 610537) PREDICTED: dipeptidyl pept (458 aa)
initn: 779 init1: 362 opt: 828 Z-score: 1055.2 bits: 204.6 E(85289): 4.9e-52
Smith-Waterman score: 828; 41.3% identity (69.2% similar) in 341 aa overlap (78-404:85-416)
50 60 70 80 90 100
pF1KE6 YSVLYFQQKVDHFGFNTVKTFNQRYLVADKYWKKNGGSILFYTGNEGDIIWFCNNTGFMW
.: .. : :.::::::::. : ::..:.
XP_016 PGALLPAASGPLQLRALRQQDLPSALPGVGFWVRGEGPIFFYTGNEGDVWAFANNSAFVA
60 70 80 90 100 110
110 120 130 140 150 160
pF1KE6 DVAEELKAMLVFAEHRYYGESLPFGDNSFKDSRHLNFLTSEQALADFAELIKHLKRTIPG
..: : :.::::::::::.::::: .: . . : ..:: ::::::::::.. :.: . :
XP_016 ELAAERGALLVFAEHRYYGKSLPFGAQSTQRG-HTELLTVEQALADFAELLRALRRDL-G
120 130 140 150 160 170
170 180 190 200 210 220
pF1KE6 AENQPVIAIGGSYGGMLAAWFRMKYPHMVVGALAASAPIWQFEDLVPCGVFMKIVTTDFR
:.. :.::.::::::::.:..::::::.:.::::::::. : . :.. ::.::.
XP_016 AQDAPAIAFGGSYGGMLSAYLRMKYPHLVAGALAASAPVLAVAGLGDSNQFFRDVTADFE
180 190 200 210 220 230
230 240 250 260 270 280
pF1KE6 KSGPHCSESIHRSWDAINRLSNTGS--GLQWLTGALHLCSPLTSQ-DIQHLKDWISETWV
..:.:........ :. : :. ..: :. :.::... :. .: . ....
XP_016 GQSPKCTQGVREAFRQIKDLFLQGAYDTVRWEFGT---CQPLSDEKDLTQLFMFARNAFT
240 250 260 270 280
290 300 310 320 330 340
pF1KE6 NLAMVDYPYASNFLQPLPAWPIKVVCQYLKNPNVSDSLLLQNIFQALNVYYNYSGQVKCL
:::.:::: ..:: :::: :.:: :. : .:.. . .. .. :: ::. .:
XP_016 VLAMMDYPYPTDFLGPLPANPVKVGCDRL----LSEAQRITGLRALAGLVYNASGSEHCY
290 300 310 320 330 340
350 360 370 380 390
pF1KE6 NISETATSSLGTLG---------WSYQACTEVVMPFCTNGVDDMFE--PHSWNLKELSDD
.: . : : :.::::::. . : .:.: ::: : . .:.. :..
XP_016 DIYRLYHSCADPTGCGTGPDARAWDYQACTEINLTFASNNVTDMFPDLPFTDELRQRSQS
350 360 370 380 390 400
400 410 420 430 440 450
pF1KE6 CFQQWGVRPRPSWITTMYGGKNISSHTNIVFSNGELDPWSGGGVTKDITDTLVAVTISEG
:. .. .:
XP_016 RQQHHLLQREPGPLGRGRDSEEPECLSHRRHHPGGSAPPRPQSLPPRRSCFRG
410 420 430 440 450
>>XP_005266132 (OMIM: 610537) PREDICTED: dipeptidyl pept (565 aa)
initn: 1198 init1: 425 opt: 771 Z-score: 981.0 bits: 191.2 E(85289): 6.6e-48
Smith-Waterman score: 1110; 37.6% identity (62.0% similar) in 524 aa overlap (52-486:35-547)
30 40 50 60 70
pF1KE6 LRPALRALGSLHLPTNPTSLPAVAKNYSVLYFQQKVDHFGFNTV--KTFNQRYLVADKYW
.:::..:::.:. ::: ::.::.:..:
XP_005 PWAPVLLLALGLRGLQAGARRAPDPGFQERFFQQRLDHFNFERFGNKTFPQRFLVSDRFW
10 20 30 40 50 60
80 90 100 110 120 130
pF1KE6 KKNGGSILFYTGNEGDIIWFCNNTGFMWDVAEELKAMLVFAEHRYYGESLPFGDNSFKDS
.. : :.::::::::. : ::..:. ..: : :.::::::::::.::::: .: . .
XP_005 VRGEGPIFFYTGNEGDVWAFANNSAFVAELAAERGALLVFAEHRYYGKSLPFGAQSTQRG
70 80 90 100 110 120
140 150 160 170
pF1KE6 RHLNFLTSEQALADFAELIKHLKRTIPGAENQPVIAIGG---------------------
: ..:: ::::::::::.. :.: . ::.. :.::.::
XP_005 -HTELLTVEQALADFAELLRALRRDL-GAQDAPAIAFGGRKPSHLSSQPPAQLGCAATLA
130 140 150 160 170 180
180
pF1KE6 ----------------------------------------------------SYGGMLAA
::::::.:
XP_005 AFPSESCTRTWPRVGICGSQKCRPPCGTCGPLRRKRGNGVLGAAALTLCPSPSYGGMLSA
190 200 210 220 230 240
190 200 210 220 230 240
pF1KE6 WFRMKYPHMVVGALAASAPIWQFEDLVPCGVFMKIVTTDFRKSGPHCSESIHRSWDAINR
..::::::.:.::::::::. : . :.. ::.::. ..:.:........ :.
XP_005 YLRMKYPHLVAGALAASAPVLAVAGLGDSNQFFRDVTADFEGQSPKCTQGVREAFRQIKD
250 260 270 280 290 300
250 260 270 280 290 300
pF1KE6 LSNTGS--GLQWLTGALHLCSPLTSQ-DIQHLKDWISETWVNLAMVDYPYASNFLQPLPA
: :. ..: :. :.::... :. .: . .... :::.:::: ..:: ::::
XP_005 LFLQGAYDTVRWEFGT---CQPLSDEKDLTQLFMFARNAFTVLAMMDYPYPTDFLGPLPA
310 320 330 340 350
310 320 330 340 350
pF1KE6 WPIKVVCQYLKNPNVSDSLLLQNIFQALNVYYNYSGQVKCLNISETATSSLGTLG-----
:.:: :. : .:.. . .. .. :: ::. .: .: . : :
XP_005 NPVKVGCDRL----LSEAQRITGLRALAGLVYNASGSEHCYDIYRLYHSCADPTGCGTGP
360 370 380 390 400 410
360 370 380 390 400 410
pF1KE6 ----WSYQACTEVVMPFCTNGVDDMFE--PHSWNLKELSDDCFQQWGVRPRPSWITTMYG
:.::::::. . : .:.: ::: : . .:.. :.. ::: :::.:. : .
XP_005 DARAWDYQACTEINLTFASNNVTDMFPDLPFTDELRQRY--CLDTWGVWPRPDWLLTSFW
420 430 440 450 460 470
420 430 440 450 460 470
pF1KE6 GKNISSHTNIVFSNGELDPWSGGGVTKDITDTLVAVTISEGAHHLDLRTKNALDPMSVLL
: .. . .::.::::.::::.:::. .... ...::::. ::::::::... :: ::.
XP_005 GGDLRAASNIIFSNGNLDPWAGGGIRRNLSASVIAVTIQGGAHHLDLRASHPEDPASVVE
480 490 500 510 520 530
480 490
pF1KE6 ARSLEVRHMKNWIRDFYDSAGKQH
::.::. . .:..
XP_005 ARKLEATIIGEWVKAARREQQPALRGGPRLSL
540 550 560
496 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Nov 8 13:06:35 2016 done: Tue Nov 8 13:06:36 2016
Total Scan time: 6.440 Total Display time: 0.050
Function used was FASTA [36.3.4 Apr, 2011]