Result of FASTA (omim) for
pFN21AE6416
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE6416, 549 aa
1>>>pF1KE6416 549 - 549 aa - 549 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.4747+/-0.000396; mu= 17.1559+/- 0.024
mean_var=61.0697+/-12.575, 0's: 0 Z-trim(111.1): 34 B-trim: 0 in 0/51
Lambda= 0.164120
statistics sampled from 19629 (19656) to 19629 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.586), E-opt: 0.2 (0.23), width: 16
Scan time: 8.410
The best scores are: opt bits E(85289)
NP_001177921 (OMIM: 603690,612539,614482) acetyl-c ( 549) 3662 876.0 0
NP_004724 (OMIM: 603690,612539,614482) acetyl-coen ( 549) 3662 876.0 0
XP_011511613 (OMIM: 603690,612539,614482) PREDICTE ( 448) 2113 509.2 1.1e-143
XP_016862952 (OMIM: 603690,612539,614482) PREDICTE ( 379) 1940 468.2 2e-131
XP_016862951 (OMIM: 603690,612539,614482) PREDICTE ( 447) 1740 420.9 4.2e-117
XP_016862953 (OMIM: 603690,612539,614482) PREDICTE ( 278) 1556 377.2 3.6e-104
>>NP_001177921 (OMIM: 603690,612539,614482) acetyl-coenz (549 aa)
initn: 3662 init1: 3662 opt: 3662 Z-score: 4681.3 bits: 876.0 E(85289): 0
Smith-Waterman score: 3662; 100.0% identity (100.0% similar) in 549 aa overlap (1-549:1-549)
10 20 30 40 50 60
pF1KE6 MSPTISHKDSSRQRRPGNFSHSLDMKSGPLPPGGWDDSHLDSAGREGDREALLGDTGTGD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MSPTISHKDSSRQRRPGNFSHSLDMKSGPLPPGGWDDSHLDSAGREGDREALLGDTGTGD
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 FLKAPQSFRAELSSILLLLFLYVLQGIPLGLAGSIPLILQSKNVSYTDQAFFSFVFWPFS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FLKAPQSFRAELSSILLLLFLYVLQGIPLGLAGSIPLILQSKNVSYTDQAFFSFVFWPFS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 LKLLWAPLVDAVYVKNFGRRKSWLVPTQYILGLFMIYLSTQVDRLLGNTDDRTPDVIALT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LKLLWAPLVDAVYVKNFGRRKSWLVPTQYILGLFMIYLSTQVDRLLGNTDDRTPDVIALT
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE6 VAFFLFEFLAATQDIAVDGWALTMLSRENVGYASTCNSVGQTAGYFLGNVLFLALESADF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VAFFLFEFLAATQDIAVDGWALTMLSRENVGYASTCNSVGQTAGYFLGNVLFLALESADF
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE6 CNKYLRFQPQPRGIVTLSDFLFFWGTVFLITTTLVALLKKENEVSVVKEETQGITDTYKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CNKYLRFQPQPRGIVTLSDFLFFWGTVFLITTTLVALLKKENEVSVVKEETQGITDTYKL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE6 LFAIIKMPAVLTFCLLILTAKIGFSAADAVTGLKLVEEGVPKEHLALLAVPMVPLQIILP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LFAIIKMPAVLTFCLLILTAKIGFSAADAVTGLKLVEEGVPKEHLALLAVPMVPLQIILP
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE6 LIISKYTAGPQPLNTFYKAMPYRLLLGLEYALLVWWTPKVEHQGGFPIYYYIVVLLSYAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LIISKYTAGPQPLNTFYKAMPYRLLLGLEYALLVWWTPKVEHQGGFPIYYYIVVLLSYAL
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE6 HQVTVYSMYVSIMAFNAKVSDPLIGGTYMTLLNTVSNLGGNWPSTVALWLVDPLTVKECV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HQVTVYSMYVSIMAFNAKVSDPLIGGTYMTLLNTVSNLGGNWPSTVALWLVDPLTVKECV
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE6 GASNQNCRTPDAVELCKKLGGSCVTALDGYYVESIICVFIGFGWWFFLGPKFKKLQDEGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GASNQNCRTPDAVELCKKLGGSCVTALDGYYVESIICVFIGFGWWFFLGPKFKKLQDEGS
490 500 510 520 530 540
pF1KE6 SSWKCKRNN
:::::::::
NP_001 SSWKCKRNN
>>NP_004724 (OMIM: 603690,612539,614482) acetyl-coenzyme (549 aa)
initn: 3662 init1: 3662 opt: 3662 Z-score: 4681.3 bits: 876.0 E(85289): 0
Smith-Waterman score: 3662; 100.0% identity (100.0% similar) in 549 aa overlap (1-549:1-549)
10 20 30 40 50 60
pF1KE6 MSPTISHKDSSRQRRPGNFSHSLDMKSGPLPPGGWDDSHLDSAGREGDREALLGDTGTGD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 MSPTISHKDSSRQRRPGNFSHSLDMKSGPLPPGGWDDSHLDSAGREGDREALLGDTGTGD
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 FLKAPQSFRAELSSILLLLFLYVLQGIPLGLAGSIPLILQSKNVSYTDQAFFSFVFWPFS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 FLKAPQSFRAELSSILLLLFLYVLQGIPLGLAGSIPLILQSKNVSYTDQAFFSFVFWPFS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 LKLLWAPLVDAVYVKNFGRRKSWLVPTQYILGLFMIYLSTQVDRLLGNTDDRTPDVIALT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 LKLLWAPLVDAVYVKNFGRRKSWLVPTQYILGLFMIYLSTQVDRLLGNTDDRTPDVIALT
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE6 VAFFLFEFLAATQDIAVDGWALTMLSRENVGYASTCNSVGQTAGYFLGNVLFLALESADF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 VAFFLFEFLAATQDIAVDGWALTMLSRENVGYASTCNSVGQTAGYFLGNVLFLALESADF
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE6 CNKYLRFQPQPRGIVTLSDFLFFWGTVFLITTTLVALLKKENEVSVVKEETQGITDTYKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 CNKYLRFQPQPRGIVTLSDFLFFWGTVFLITTTLVALLKKENEVSVVKEETQGITDTYKL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE6 LFAIIKMPAVLTFCLLILTAKIGFSAADAVTGLKLVEEGVPKEHLALLAVPMVPLQIILP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 LFAIIKMPAVLTFCLLILTAKIGFSAADAVTGLKLVEEGVPKEHLALLAVPMVPLQIILP
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE6 LIISKYTAGPQPLNTFYKAMPYRLLLGLEYALLVWWTPKVEHQGGFPIYYYIVVLLSYAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 LIISKYTAGPQPLNTFYKAMPYRLLLGLEYALLVWWTPKVEHQGGFPIYYYIVVLLSYAL
370 380 390 400 410 420
430 440 450 460 470 480
pF1KE6 HQVTVYSMYVSIMAFNAKVSDPLIGGTYMTLLNTVSNLGGNWPSTVALWLVDPLTVKECV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 HQVTVYSMYVSIMAFNAKVSDPLIGGTYMTLLNTVSNLGGNWPSTVALWLVDPLTVKECV
430 440 450 460 470 480
490 500 510 520 530 540
pF1KE6 GASNQNCRTPDAVELCKKLGGSCVTALDGYYVESIICVFIGFGWWFFLGPKFKKLQDEGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 GASNQNCRTPDAVELCKKLGGSCVTALDGYYVESIICVFIGFGWWFFLGPKFKKLQDEGS
490 500 510 520 530 540
pF1KE6 SSWKCKRNN
:::::::::
NP_004 SSWKCKRNN
>>XP_011511613 (OMIM: 603690,612539,614482) PREDICTED: a (448 aa)
initn: 2113 init1: 2113 opt: 2113 Z-score: 2700.6 bits: 509.2 E(85289): 1.1e-143
Smith-Waterman score: 2782; 81.6% identity (81.6% similar) in 549 aa overlap (1-549:1-448)
10 20 30 40 50 60
pF1KE6 MSPTISHKDSSRQRRPGNFSHSLDMKSGPLPPGGWDDSHLDSAGREGDREALLGDTGTGD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MSPTISHKDSSRQRRPGNFSHSLDMKSGPLPPGGWDDSHLDSAGREGDREALLGDTGTGD
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 FLKAPQSFRAELSSILLLLFLYVLQGIPLGLAGSIPLILQSKNVSYTDQAFFSFVFWPFS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 FLKAPQSFRAELSSILLLLFLYVLQGIPLGLAGSIPLILQSKNVSYTDQAFFSFVFWPFS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 LKLLWAPLVDAVYVKNFGRRKSWLVPTQYILGLFMIYLSTQVDRLLGNTDDRTPDVIALT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LKLLWAPLVDAVYVKNFGRRKSWLVPTQYILGLFMIYLSTQVDRLLGNTDDRTPDVIALT
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE6 VAFFLFEFLAATQDIAVDGWALTMLSRENVGYASTCNSVGQTAGYFLGNVLFLALESADF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VAFFLFEFLAATQDIAVDGWALTMLSRENVGYASTCNSVGQTAGYFLGNVLFLALESADF
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE6 CNKYLRFQPQPRGIVTLSDFLFFWGTVFLITTTLVALLKKENEVSVVKEETQGITDTYKL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CNKYLRFQPQPRGIVTLSDFLFFWGTVFLITTTLVALLKKENEVSVVKEETQGITDTYKL
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE6 LFAIIKMPAVLTFCLLILTAKIGFSAADAVTGLKLVEEGVPKEHLALLAVPMVPLQIILP
:::::::::::::::::::::
XP_011 LFAIIKMPAVLTFCLLILTAK---------------------------------------
310 320
370 380 390 400 410 420
pF1KE6 LIISKYTAGPQPLNTFYKAMPYRLLLGLEYALLVWWTPKVEHQGGFPIYYYIVVLLSYAL
XP_011 ------------------------------------------------------------
430 440 450 460 470 480
pF1KE6 HQVTVYSMYVSIMAFNAKVSDPLIGGTYMTLLNTVSNLGGNWPSTVALWLVDPLTVKECV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 --VTVYSMYVSIMAFNAKVSDPLIGGTYMTLLNTVSNLGGNWPSTVALWLVDPLTVKECV
330 340 350 360 370
490 500 510 520 530 540
pF1KE6 GASNQNCRTPDAVELCKKLGGSCVTALDGYYVESIICVFIGFGWWFFLGPKFKKLQDEGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GASNQNCRTPDAVELCKKLGGSCVTALDGYYVESIICVFIGFGWWFFLGPKFKKLQDEGS
380 390 400 410 420 430
pF1KE6 SSWKCKRNN
:::::::::
XP_011 SSWKCKRNN
440
>>XP_016862952 (OMIM: 603690,612539,614482) PREDICTED: a (379 aa)
initn: 1966 init1: 1940 opt: 1940 Z-score: 2480.4 bits: 468.2 E(85289): 2e-131
Smith-Waterman score: 1940; 100.0% identity (100.0% similar) in 291 aa overlap (259-549:89-379)
230 240 250 260 270 280
pF1KE6 NVLFLALESADFCNKYLRFQPQPRGIVTLSDFLFFWGTVFLITTTLVALLKKENEVSVVK
::::::::::::::::::::::::::::::
XP_016 VRFIYPFERVCDVGGKLINLLEIIVWEITQDFLFFWGTVFLITTTLVALLKKENEVSVVK
60 70 80 90 100 110
290 300 310 320 330 340
pF1KE6 EETQGITDTYKLLFAIIKMPAVLTFCLLILTAKIGFSAADAVTGLKLVEEGVPKEHLALL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EETQGITDTYKLLFAIIKMPAVLTFCLLILTAKIGFSAADAVTGLKLVEEGVPKEHLALL
120 130 140 150 160 170
350 360 370 380 390 400
pF1KE6 AVPMVPLQIILPLIISKYTAGPQPLNTFYKAMPYRLLLGLEYALLVWWTPKVEHQGGFPI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 AVPMVPLQIILPLIISKYTAGPQPLNTFYKAMPYRLLLGLEYALLVWWTPKVEHQGGFPI
180 190 200 210 220 230
410 420 430 440 450 460
pF1KE6 YYYIVVLLSYALHQVTVYSMYVSIMAFNAKVSDPLIGGTYMTLLNTVSNLGGNWPSTVAL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YYYIVVLLSYALHQVTVYSMYVSIMAFNAKVSDPLIGGTYMTLLNTVSNLGGNWPSTVAL
240 250 260 270 280 290
470 480 490 500 510 520
pF1KE6 WLVDPLTVKECVGASNQNCRTPDAVELCKKLGGSCVTALDGYYVESIICVFIGFGWWFFL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 WLVDPLTVKECVGASNQNCRTPDAVELCKKLGGSCVTALDGYYVESIICVFIGFGWWFFL
300 310 320 330 340 350
530 540
pF1KE6 GPKFKKLQDEGSSSWKCKRNN
:::::::::::::::::::::
XP_016 GPKFKKLQDEGSSSWKCKRNN
360 370
>>XP_016862951 (OMIM: 603690,612539,614482) PREDICTED: a (447 aa)
initn: 2618 init1: 1740 opt: 1740 Z-score: 2223.3 bits: 420.9 E(85289): 4.2e-117
Smith-Waterman score: 2449; 74.1% identity (78.1% similar) in 549 aa overlap (1-549:1-447)
10 20 30 40 50 60
pF1KE6 MSPTISHKDSSRQRRPGNFSHSLDMKSGPLPPGGWDDSHLDSAGREGDREALLGDTGTGD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MSPTISHKDSSRQRRPGNFSHSLDMKSGPLPPGGWDDSHLDSAGREGDREALLGDTGTGD
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 FLKAPQSFRAELSSILLLLFLYVLQGIPLGLAGSIPLILQSKNVSYTDQAFFSFVFWPFS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 FLKAPQSFRAELSSILLLLFLYVLQGIPLGLAGSIPLILQSKNVSYTDQAFFSFVFWPFS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 LKLLWAPLVDAVYVKNFGRRKSWLVPTQYILGLFMIYLSTQVDRLLGNTDDRTPDVIALT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LKLLWAPLVDAVYVKNFGRRKSWLVPTQYILGLFMIYLSTQVDRLLGNTDDRTPDVIALT
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE6 VAFFLFEFLAATQDIAVDGWALTMLSRENVGYASTCNSVGQTAGYFLGNVLFLALESADF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 VAFFLFEFLAATQDIAVDGWALTMLSRENVGYASTCNSVGQTAGYFLGNVLFLALESADF
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE6 CNKYLRFQPQPRGIVTLSDFLFFWGTVFLITTTLVALLKKENEVSVVKEETQGITDTYKL
:::::::::::::::::::..: . ...:.. .: :.
XP_016 CNKYLRFQPQPRGIVTLSDWFF------------SSRCCNRTEIG-----RRGSTQR---
250 260 270 280
310 320 330 340 350 360
pF1KE6 LFAIIKMPAVLTFCLLILTAKIGFSAADAVTGLKLVEEGVPKEHLALLAVPMVPLQIILP
:: : :: : ..
XP_016 -----------TFSL------IGSSNGS--------------------------------
290
370 380 390 400 410 420
pF1KE6 LIISKYTAGPQPLNTFYKAMPYRLLLGLEYALLVWWTPKVEHQGGFPIYYYIVVLLSYAL
.. ::. :. . : .: ..: .: :.::
XP_016 --FADNTASD------YQQIHCR-------------SPAIKH-----------ILQSHAL
300 310
430 440 450 460 470 480
pF1KE6 HQVTVYSMYVSIMAFNAKVSDPLIGGTYMTLLNTVSNLGGNWPSTVALWLVDPLTVKECV
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 -QVTVYSMYVSIMAFNAKVSDPLIGGTYMTLLNTVSNLGGNWPSTVALWLVDPLTVKECV
320 330 340 350 360 370
490 500 510 520 530 540
pF1KE6 GASNQNCRTPDAVELCKKLGGSCVTALDGYYVESIICVFIGFGWWFFLGPKFKKLQDEGS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 GASNQNCRTPDAVELCKKLGGSCVTALDGYYVESIICVFIGFGWWFFLGPKFKKLQDEGS
380 390 400 410 420 430
pF1KE6 SSWKCKRNN
:::::::::
XP_016 SSWKCKRNN
440
>>XP_016862953 (OMIM: 603690,612539,614482) PREDICTED: a (278 aa)
initn: 1582 init1: 1556 opt: 1556 Z-score: 1991.2 bits: 377.2 E(85289): 3.6e-104
Smith-Waterman score: 1556; 98.7% identity (99.1% similar) in 232 aa overlap (318-549:47-278)
290 300 310 320 330 340
pF1KE6 KEETQGITDTYKLLFAIIKMPAVLTFCLLILTAKIGFSAADAVTGLKLVEEGVPKEHLAL
: .::::::::::::::::::::::::::
XP_016 TFWAMFCFWPLNLPTFVTNICGFSLNPEESLLFQIGFSAADAVTGLKLVEEGVPKEHLAL
20 30 40 50 60 70
350 360 370 380 390 400
pF1KE6 LAVPMVPLQIILPLIISKYTAGPQPLNTFYKAMPYRLLLGLEYALLVWWTPKVEHQGGFP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LAVPMVPLQIILPLIISKYTAGPQPLNTFYKAMPYRLLLGLEYALLVWWTPKVEHQGGFP
80 90 100 110 120 130
410 420 430 440 450 460
pF1KE6 IYYYIVVLLSYALHQVTVYSMYVSIMAFNAKVSDPLIGGTYMTLLNTVSNLGGNWPSTVA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IYYYIVVLLSYALHQVTVYSMYVSIMAFNAKVSDPLIGGTYMTLLNTVSNLGGNWPSTVA
140 150 160 170 180 190
470 480 490 500 510 520
pF1KE6 LWLVDPLTVKECVGASNQNCRTPDAVELCKKLGGSCVTALDGYYVESIICVFIGFGWWFF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LWLVDPLTVKECVGASNQNCRTPDAVELCKKLGGSCVTALDGYYVESIICVFIGFGWWFF
200 210 220 230 240 250
530 540
pF1KE6 LGPKFKKLQDEGSSSWKCKRNN
::::::::::::::::::::::
XP_016 LGPKFKKLQDEGSSSWKCKRNN
260 270
549 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Nov 8 13:04:16 2016 done: Tue Nov 8 13:04:18 2016
Total Scan time: 8.410 Total Display time: 0.020
Function used was FASTA [36.3.4 Apr, 2011]