Result of FASTA (omim) for
pFN21AE6401
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE6401, 477 aa
1>>>pF1KE6401 477 - 477 aa - 477 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.3263+/-0.000324; mu= 19.3154+/- 0.020
mean_var=98.9826+/-21.141, 0's: 0 Z-trim(116.9): 196 B-trim: 0 in 0/58
Lambda= 0.128912
statistics sampled from 28193 (28427) to 28193 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.681), E-opt: 0.2 (0.333), width: 16
Scan time: 7.930
The best scores are: opt bits E(85289)
NP_055395 (OMIM: 605245) solute carrier family 2, ( 477) 3186 603.0 5.7e-172
XP_006717147 (OMIM: 605245) PREDICTED: solute carr ( 437) 2881 546.3 6.3e-155
NP_001258640 (OMIM: 605245) solute carrier family ( 411) 2557 486.0 8.4e-137
XP_011516905 (OMIM: 605245) PREDICTED: solute carr ( 342) 2234 425.8 8.9e-119
NP_001258641 (OMIM: 605245) solute carrier family ( 314) 2099 400.7 3.1e-111
XP_011516904 (OMIM: 605245) PREDICTED: solute carr ( 451) 1656 318.5 2.5e-86
XP_016870142 (OMIM: 605245) PREDICTED: solute carr ( 248) 1470 283.6 4.3e-76
XP_011516906 (OMIM: 605245) PREDICTED: solute carr ( 316) 1378 266.6 7.1e-71
NP_060055 (OMIM: 606813) solute carrier family 2, ( 507) 885 175.1 3.9e-43
NP_001138571 (OMIM: 606813) solute carrier family ( 445) 872 172.7 1.9e-42
XP_016869725 (OMIM: 606813) PREDICTED: solute carr ( 345) 793 157.8 4.3e-38
NP_001273163 (OMIM: 611039) solute carrier family ( 497) 561 114.9 5.3e-25
XP_016874335 (OMIM: 611039) PREDICTED: solute carr ( 497) 561 114.9 5.3e-25
NP_001273164 (OMIM: 611039) solute carrier family ( 497) 561 114.9 5.3e-25
XP_005253372 (OMIM: 611039) PREDICTED: solute carr ( 497) 561 114.9 5.3e-25
XP_005253374 (OMIM: 611039) PREDICTED: solute carr ( 497) 561 114.9 5.3e-25
XP_011518865 (OMIM: 611039) PREDICTED: solute carr ( 497) 561 114.9 5.3e-25
XP_011518864 (OMIM: 611039) PREDICTED: solute carr ( 497) 561 114.9 5.3e-25
XP_016874336 (OMIM: 611039) PREDICTED: solute carr ( 497) 561 114.9 5.3e-25
NP_703150 (OMIM: 611039) solute carrier family 2, ( 520) 561 114.9 5.5e-25
NP_001273162 (OMIM: 611039) solute carrier family ( 520) 561 114.9 5.5e-25
XP_016874330 (OMIM: 611039) PREDICTED: solute carr ( 521) 561 114.9 5.5e-25
XP_016874333 (OMIM: 611039) PREDICTED: solute carr ( 521) 561 114.9 5.5e-25
XP_016874331 (OMIM: 611039) PREDICTED: solute carr ( 521) 561 114.9 5.5e-25
XP_016874334 (OMIM: 611039) PREDICTED: solute carr ( 521) 561 114.9 5.5e-25
XP_016874332 (OMIM: 611039) PREDICTED: solute carr ( 521) 561 114.9 5.5e-25
NP_001273166 (OMIM: 611039) solute carrier family ( 535) 561 114.9 5.6e-25
XP_016869727 (OMIM: 606813) PREDICTED: solute carr ( 263) 549 112.3 1.6e-24
XP_016869726 (OMIM: 606813) PREDICTED: solute carr ( 263) 549 112.3 1.6e-24
XP_011516491 (OMIM: 606813) PREDICTED: solute carr ( 301) 549 112.4 1.8e-24
XP_011518866 (OMIM: 611039) PREDICTED: solute carr ( 411) 506 104.6 5.6e-22
XP_011518867 (OMIM: 611039) PREDICTED: solute carr ( 411) 506 104.6 5.6e-22
NP_001273165 (OMIM: 611039) solute carrier family ( 411) 506 104.6 5.6e-22
XP_011511389 (OMIM: 125853,138160,227810) PREDICTE ( 509) 472 98.3 5.2e-20
NP_000331 (OMIM: 125853,138160,227810) solute carr ( 524) 472 98.3 5.3e-20
NP_001265587 (OMIM: 125853,138160,227810) solute c ( 405) 426 89.7 1.7e-17
NP_001315549 (OMIM: 138230) solute carrier family ( 457) 421 88.8 3.5e-17
XP_005263548 (OMIM: 138230) PREDICTED: solute carr ( 501) 421 88.8 3.7e-17
XP_016857627 (OMIM: 138230) PREDICTED: solute carr ( 501) 421 88.8 3.7e-17
XP_016857625 (OMIM: 138230) PREDICTED: solute carr ( 501) 421 88.8 3.7e-17
XP_016857624 (OMIM: 138230) PREDICTED: solute carr ( 501) 421 88.8 3.7e-17
NP_001315548 (OMIM: 138230) solute carrier family ( 501) 421 88.8 3.7e-17
XP_016857622 (OMIM: 138230) PREDICTED: solute carr ( 501) 421 88.8 3.7e-17
NP_003030 (OMIM: 138230) solute carrier family 2, ( 501) 421 88.8 3.7e-17
XP_016857623 (OMIM: 138230) PREDICTED: solute carr ( 501) 421 88.8 3.7e-17
XP_016857626 (OMIM: 138230) PREDICTED: solute carr ( 501) 421 88.8 3.7e-17
XP_016857629 (OMIM: 138230) PREDICTED: solute carr ( 501) 421 88.8 3.7e-17
XP_016857630 (OMIM: 138230) PREDICTED: solute carr ( 501) 421 88.8 3.7e-17
XP_011527367 (OMIM: 208050,606145) PREDICTED: solu ( 494) 419 88.5 4.7e-17
XP_011527366 (OMIM: 208050,606145) PREDICTED: solu ( 507) 419 88.5 4.8e-17
>>NP_055395 (OMIM: 605245) solute carrier family 2, faci (477 aa)
initn: 3186 init1: 3186 opt: 3186 Z-score: 3208.5 bits: 603.0 E(85289): 5.7e-172
Smith-Waterman score: 3186; 100.0% identity (100.0% similar) in 477 aa overlap (1-477:1-477)
10 20 30 40 50 60
pF1KE6 MTPEDPEETQPLLGPPGGSAPRGRRVFLAAFAAALGPLSFGFALGYSSPAIPSLQRAAPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 MTPEDPEETQPLLGPPGGSAPRGRRVFLAAFAAALGPLSFGFALGYSSPAIPSLQRAAPP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 APRLDDAAASWFGAVVTLGAAAGGVLGGWLVDRAGRKLSLLLCSVPFVAGFAVITAAQDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 APRLDDAAASWFGAVVTLGAAAGGVLGGWLVDRAGRKLSLLLCSVPFVAGFAVITAAQDV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 WMLLGGRLLTGLACGVASLVAPVYISEIAYPAVRGLLGSCVQLMVVVGILLAYLAGWVLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 WMLLGGRLLTGLACGVASLVAPVYISEIAYPAVRGLLGSCVQLMVVVGILLAYLAGWVLE
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE6 WRWLAVLGCVPPSLMLLLMCFMPETPRFLLTQHRRQEAMAALRFLWGSEQGWEDPPIGAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 WRWLAVLGCVPPSLMLLLMCFMPETPRFLLTQHRRQEAMAALRFLWGSEQGWEDPPIGAE
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE6 QSFHLALLRQPGIYKPFIIGVSLMAFQQLSGVNAVMFYAETIFEEAKFKDSSLASVVVGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 QSFHLALLRQPGIYKPFIIGVSLMAFQQLSGVNAVMFYAETIFEEAKFKDSSLASVVVGV
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE6 IQVLFTAVAALIMDRAGRRLLLVLSGVVMVFSTSAFGAYFKLTQGGPGNSSHVAISAPVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 IQVLFTAVAALIMDRAGRRLLLVLSGVVMVFSTSAFGAYFKLTQGGPGNSSHVAISAPVS
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE6 AQPVDASVGLAWLAVGSMCLFIAGFAVGWGPIPWLLMSEIFPLHVKGVATGICVLTNWLM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 AQPVDASVGLAWLAVGSMCLFIAGFAVGWGPIPWLLMSEIFPLHVKGVATGICVLTNWLM
370 380 390 400 410 420
430 440 450 460 470
pF1KE6 AFLVTKEFSSLMEVLRPYGAFWLASAFCIFSVLFTLFCVPETKGKTLEQITAHFEGR
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_055 AFLVTKEFSSLMEVLRPYGAFWLASAFCIFSVLFTLFCVPETKGKTLEQITAHFEGR
430 440 450 460 470
>>XP_006717147 (OMIM: 605245) PREDICTED: solute carrier (437 aa)
initn: 2927 init1: 2881 opt: 2881 Z-score: 2902.4 bits: 546.3 E(85289): 6.3e-155
Smith-Waterman score: 2881; 99.5% identity (99.8% similar) in 435 aa overlap (1-435:1-435)
10 20 30 40 50 60
pF1KE6 MTPEDPEETQPLLGPPGGSAPRGRRVFLAAFAAALGPLSFGFALGYSSPAIPSLQRAAPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 MTPEDPEETQPLLGPPGGSAPRGRRVFLAAFAAALGPLSFGFALGYSSPAIPSLQRAAPP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 APRLDDAAASWFGAVVTLGAAAGGVLGGWLVDRAGRKLSLLLCSVPFVAGFAVITAAQDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 APRLDDAAASWFGAVVTLGAAAGGVLGGWLVDRAGRKLSLLLCSVPFVAGFAVITAAQDV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 WMLLGGRLLTGLACGVASLVAPVYISEIAYPAVRGLLGSCVQLMVVVGILLAYLAGWVLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 WMLLGGRLLTGLACGVASLVAPVYISEIAYPAVRGLLGSCVQLMVVVGILLAYLAGWVLE
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE6 WRWLAVLGCVPPSLMLLLMCFMPETPRFLLTQHRRQEAMAALRFLWGSEQGWEDPPIGAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 WRWLAVLGCVPPSLMLLLMCFMPETPRFLLTQHRRQEAMAALRFLWGSEQGWEDPPIGAE
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE6 QSFHLALLRQPGIYKPFIIGVSLMAFQQLSGVNAVMFYAETIFEEAKFKDSSLASVVVGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 QSFHLALLRQPGIYKPFIIGVSLMAFQQLSGVNAVMFYAETIFEEAKFKDSSLASVVVGV
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE6 IQVLFTAVAALIMDRAGRRLLLVLSGVVMVFSTSAFGAYFKLTQGGPGNSSHVAISAPVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 IQVLFTAVAALIMDRAGRRLLLVLSGVVMVFSTSAFGAYFKLTQGGPGNSSHVAISAPVS
310 320 330 340 350 360
370 380 390 400 410 420
pF1KE6 AQPVDASVGLAWLAVGSMCLFIAGFAVGWGPIPWLLMSEIFPLHVKGVATGICVLTNWLM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_006 AQPVDASVGLAWLAVGSMCLFIAGFAVGWGPIPWLLMSEIFPLHVKGVATGICVLTNWLM
370 380 390 400 410 420
430 440 450 460 470
pF1KE6 AFLVTKEFSSLMEVLRPYGAFWLASAFCIFSVLFTLFCVPETKGKTLEQITAHFEGR
:::::::::::: .:
XP_006 AFLVTKEFSSLMLLLLL
430
>>NP_001258640 (OMIM: 605245) solute carrier family 2, f (411 aa)
initn: 2544 init1: 2544 opt: 2557 Z-score: 2577.0 bits: 486.0 E(85289): 8.4e-137
Smith-Waterman score: 2557; 95.8% identity (97.1% similar) in 407 aa overlap (1-406:1-402)
10 20 30 40 50 60
pF1KE6 MTPEDPEETQPLLGPPGGSAPRGRRVFLAAFAAALGPLSFGFALGYSSPAIPSLQRAAPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MTPEDPEETQPLLGPPGGSAPRGRRVFLAAFAAALGPLSFGFALGYSSPAIPSLQRAAPP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 APRLDDAAASWFGAVVTLGAAAGGVLGGWLVDRAGRKLSLLLCSVPFVAGFAVITAAQDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 APRLDDAAASWFGAVVTLGAAAGGVLGGWLVDRAGRKLSLLLCSVPFVAGFAVITAAQDV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 WMLLGGRLLTGLACGVASLVAPVYISEIAYPAVRGLLGSCVQLMVVVGILLAYLAGWVLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 WMLLGGRLLTGLACGVASLVAPVYISEIAYPAVRGLLGSCVQLMVVVGILLAYLAGWVLE
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE6 WRWLAVLGCVPPSLMLLLMCFMPETPRFLLTQHRRQEAMAALRFLWGSEQGWEDPPIGAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 WRWLAVLGCVPPSLMLLLMCFMPETPRFLLTQHRRQEAMAALRFLWGSEQGWEDPPIGAE
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE6 QSFHLALLRQPGIYKPFIIGVSLMAFQQLSGVNAVMFYAETIFEEAKFKDSSLASVVVGV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QSFHLALLRQPGIYKPFIIGVSLMAFQQLSGVNAVMFYAETIFEEAKFKDSSLASVVVGV
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE6 IQVLFTAVAALIMDRAGRRLLLVLSGVVMVFSTSAFGAYFKLTQGGPGNSSHVAISAPVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IQVLFTAVAALIMDRAGRRLLLVLSGVVMVFSTSAFGAYFKLTQGGPGNSSHVAISAPVS
310 320 330 340 350 360
370 380 390 400 410
pF1KE6 AQPVDASVGLAWLAVGSMCLFIAGFAVGWGPIP-WLLMSEIFPLHVKGVATGICVLTNWL
:::::::::::::::::::::::: :: : :.. . ::..
NP_001 AQPVDASVGLAWLAVGSMCLFIAG-----GPQALWSLLACLRFLHLQCPFHFVLCP
370 380 390 400 410
420 430 440 450 460 470
pF1KE6 MAFLVTKEFSSLMEVLRPYGAFWLASAFCIFSVLFTLFCVPETKGKTLEQITAHFEGR
>>XP_011516905 (OMIM: 605245) PREDICTED: solute carrier (342 aa)
initn: 2234 init1: 2234 opt: 2234 Z-score: 2253.4 bits: 425.8 E(85289): 8.9e-119
Smith-Waterman score: 2234; 100.0% identity (100.0% similar) in 335 aa overlap (143-477:8-342)
120 130 140 150 160 170
pF1KE6 VITAAQDVWMLLGGRLLTGLACGVASLVAPVYISEIAYPAVRGLLGSCVQLMVVVGILLA
::::::::::::::::::::::::::::::
XP_011 MTCSLGKVYISEIAYPAVRGLLGSCVQLMVVVGILLA
10 20 30
180 190 200 210 220 230
pF1KE6 YLAGWVLEWRWLAVLGCVPPSLMLLLMCFMPETPRFLLTQHRRQEAMAALRFLWGSEQGW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YLAGWVLEWRWLAVLGCVPPSLMLLLMCFMPETPRFLLTQHRRQEAMAALRFLWGSEQGW
40 50 60 70 80 90
240 250 260 270 280 290
pF1KE6 EDPPIGAEQSFHLALLRQPGIYKPFIIGVSLMAFQQLSGVNAVMFYAETIFEEAKFKDSS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 EDPPIGAEQSFHLALLRQPGIYKPFIIGVSLMAFQQLSGVNAVMFYAETIFEEAKFKDSS
100 110 120 130 140 150
300 310 320 330 340 350
pF1KE6 LASVVVGVIQVLFTAVAALIMDRAGRRLLLVLSGVVMVFSTSAFGAYFKLTQGGPGNSSH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LASVVVGVIQVLFTAVAALIMDRAGRRLLLVLSGVVMVFSTSAFGAYFKLTQGGPGNSSH
160 170 180 190 200 210
360 370 380 390 400 410
pF1KE6 VAISAPVSAQPVDASVGLAWLAVGSMCLFIAGFAVGWGPIPWLLMSEIFPLHVKGVATGI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VAISAPVSAQPVDASVGLAWLAVGSMCLFIAGFAVGWGPIPWLLMSEIFPLHVKGVATGI
220 230 240 250 260 270
420 430 440 450 460 470
pF1KE6 CVLTNWLMAFLVTKEFSSLMEVLRPYGAFWLASAFCIFSVLFTLFCVPETKGKTLEQITA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CVLTNWLMAFLVTKEFSSLMEVLRPYGAFWLASAFCIFSVLFTLFCVPETKGKTLEQITA
280 290 300 310 320 330
pF1KE6 HFEGR
:::::
XP_011 HFEGR
340
>>NP_001258641 (OMIM: 605245) solute carrier family 2, f (314 aa)
initn: 2099 init1: 2099 opt: 2099 Z-score: 2118.1 bits: 400.7 E(85289): 3.1e-111
Smith-Waterman score: 2099; 100.0% identity (100.0% similar) in 314 aa overlap (164-477:1-314)
140 150 160 170 180 190
pF1KE6 CGVASLVAPVYISEIAYPAVRGLLGSCVQLMVVVGILLAYLAGWVLEWRWLAVLGCVPPS
::::::::::::::::::::::::::::::
NP_001 MVVVGILLAYLAGWVLEWRWLAVLGCVPPS
10 20 30
200 210 220 230 240 250
pF1KE6 LMLLLMCFMPETPRFLLTQHRRQEAMAALRFLWGSEQGWEDPPIGAEQSFHLALLRQPGI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LMLLLMCFMPETPRFLLTQHRRQEAMAALRFLWGSEQGWEDPPIGAEQSFHLALLRQPGI
40 50 60 70 80 90
260 270 280 290 300 310
pF1KE6 YKPFIIGVSLMAFQQLSGVNAVMFYAETIFEEAKFKDSSLASVVVGVIQVLFTAVAALIM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YKPFIIGVSLMAFQQLSGVNAVMFYAETIFEEAKFKDSSLASVVVGVIQVLFTAVAALIM
100 110 120 130 140 150
320 330 340 350 360 370
pF1KE6 DRAGRRLLLVLSGVVMVFSTSAFGAYFKLTQGGPGNSSHVAISAPVSAQPVDASVGLAWL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DRAGRRLLLVLSGVVMVFSTSAFGAYFKLTQGGPGNSSHVAISAPVSAQPVDASVGLAWL
160 170 180 190 200 210
380 390 400 410 420 430
pF1KE6 AVGSMCLFIAGFAVGWGPIPWLLMSEIFPLHVKGVATGICVLTNWLMAFLVTKEFSSLME
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AVGSMCLFIAGFAVGWGPIPWLLMSEIFPLHVKGVATGICVLTNWLMAFLVTKEFSSLME
220 230 240 250 260 270
440 450 460 470
pF1KE6 VLRPYGAFWLASAFCIFSVLFTLFCVPETKGKTLEQITAHFEGR
::::::::::::::::::::::::::::::::::::::::::::
NP_001 VLRPYGAFWLASAFCIFSVLFTLFCVPETKGKTLEQITAHFEGR
280 290 300 310
>>XP_011516904 (OMIM: 605245) PREDICTED: solute carrier (451 aa)
initn: 1646 init1: 1646 opt: 1656 Z-score: 1670.9 bits: 318.5 E(85289): 2.5e-86
Smith-Waterman score: 2952; 94.5% identity (94.5% similar) in 477 aa overlap (1-477:1-451)
10 20 30 40 50 60
pF1KE6 MTPEDPEETQPLLGPPGGSAPRGRRVFLAAFAAALGPLSFGFALGYSSPAIPSLQRAAPP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MTPEDPEETQPLLGPPGGSAPRGRRVFLAAFAAALGPLSFGFALGYSSPAIPSLQRAAPP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 APRLDDAAASWFGAVVTLGAAAGGVLGGWLVDRAGRKLSLLLCSVPFVAGFAVITAAQDV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 APRLDDAAASWFGAVVTLGAAAGGVLGGWLVDRAGRKLSLLLCSVPFVAGFAVITAAQDV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 WMLLGGRLLTGLACGVASLVAPVYISEIAYPAVRGLLGSCVQLMVVVGILLAYLAGWVLE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 WMLLGGRLLTGLACGVASLVAPVYISEIAYPAVRGLLGSCVQLMVVVGILLAYLAGWVLE
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE6 WRWLAVLGCVPPSLMLLLMCFMPETPRFLLTQHRRQEAMAALRFLWGSEQGWEDPPIGAE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 WRWLAVLGCVPPSLMLLLMCFMPETPRFLLTQHRRQEAMAALRFLWGSEQGWEDPPIGAE
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE6 QSFHLALLRQPGIYKPFIIGVSLMAFQQLSGVNAVMFYAETIFEEAKFKDSSLASVVVGV
: :::::::::::::::::::::::::::::::::
XP_011 Q--------------------------QLSGVNAVMFYAETIFEEAKFKDSSLASVVVGV
250 260 270
310 320 330 340 350 360
pF1KE6 IQVLFTAVAALIMDRAGRRLLLVLSGVVMVFSTSAFGAYFKLTQGGPGNSSHVAISAPVS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IQVLFTAVAALIMDRAGRRLLLVLSGVVMVFSTSAFGAYFKLTQGGPGNSSHVAISAPVS
280 290 300 310 320 330
370 380 390 400 410 420
pF1KE6 AQPVDASVGLAWLAVGSMCLFIAGFAVGWGPIPWLLMSEIFPLHVKGVATGICVLTNWLM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AQPVDASVGLAWLAVGSMCLFIAGFAVGWGPIPWLLMSEIFPLHVKGVATGICVLTNWLM
340 350 360 370 380 390
430 440 450 460 470
pF1KE6 AFLVTKEFSSLMEVLRPYGAFWLASAFCIFSVLFTLFCVPETKGKTLEQITAHFEGR
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 AFLVTKEFSSLMEVLRPYGAFWLASAFCIFSVLFTLFCVPETKGKTLEQITAHFEGR
400 410 420 430 440 450
>>XP_016870142 (OMIM: 605245) PREDICTED: solute carrier (248 aa)
initn: 1457 init1: 1457 opt: 1470 Z-score: 1487.2 bits: 283.6 E(85289): 4.3e-76
Smith-Waterman score: 1470; 93.0% identity (95.1% similar) in 244 aa overlap (164-406:1-239)
140 150 160 170 180 190
pF1KE6 CGVASLVAPVYISEIAYPAVRGLLGSCVQLMVVVGILLAYLAGWVLEWRWLAVLGCVPPS
::::::::::::::::::::::::::::::
XP_016 MVVVGILLAYLAGWVLEWRWLAVLGCVPPS
10 20 30
200 210 220 230 240 250
pF1KE6 LMLLLMCFMPETPRFLLTQHRRQEAMAALRFLWGSEQGWEDPPIGAEQSFHLALLRQPGI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 LMLLLMCFMPETPRFLLTQHRRQEAMAALRFLWGSEQGWEDPPIGAEQSFHLALLRQPGI
40 50 60 70 80 90
260 270 280 290 300 310
pF1KE6 YKPFIIGVSLMAFQQLSGVNAVMFYAETIFEEAKFKDSSLASVVVGVIQVLFTAVAALIM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YKPFIIGVSLMAFQQLSGVNAVMFYAETIFEEAKFKDSSLASVVVGVIQVLFTAVAALIM
100 110 120 130 140 150
320 330 340 350 360 370
pF1KE6 DRAGRRLLLVLSGVVMVFSTSAFGAYFKLTQGGPGNSSHVAISAPVSAQPVDASVGLAWL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DRAGRRLLLVLSGVVMVFSTSAFGAYFKLTQGGPGNSSHVAISAPVSAQPVDASVGLAWL
160 170 180 190 200 210
380 390 400 410 420 430
pF1KE6 AVGSMCLFIAGFAVGWGPIP-WLLMSEIFPLHVKGVATGICVLTNWLMAFLVTKEFSSLM
::::::::::: :: : :.. . ::..
XP_016 AVGSMCLFIAG-----GPQALWSLLACLRFLHLQCPFHFVLCP
220 230 240
440 450 460 470
pF1KE6 EVLRPYGAFWLASAFCIFSVLFTLFCVPETKGKTLEQITAHFEGR
>>XP_011516906 (OMIM: 605245) PREDICTED: solute carrier (316 aa)
initn: 1378 init1: 1378 opt: 1378 Z-score: 1393.4 bits: 266.6 E(85289): 7.1e-71
Smith-Waterman score: 2000; 92.2% identity (92.2% similar) in 335 aa overlap (143-477:8-316)
120 130 140 150 160 170
pF1KE6 VITAAQDVWMLLGGRLLTGLACGVASLVAPVYISEIAYPAVRGLLGSCVQLMVVVGILLA
::::::::::::::::::::::::::::::
XP_011 MTCSLGKVYISEIAYPAVRGLLGSCVQLMVVVGILLA
10 20 30
180 190 200 210 220 230
pF1KE6 YLAGWVLEWRWLAVLGCVPPSLMLLLMCFMPETPRFLLTQHRRQEAMAALRFLWGSEQGW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YLAGWVLEWRWLAVLGCVPPSLMLLLMCFMPETPRFLLTQHRRQEAMAALRFLWGSEQGW
40 50 60 70 80 90
240 250 260 270 280 290
pF1KE6 EDPPIGAEQSFHLALLRQPGIYKPFIIGVSLMAFQQLSGVNAVMFYAETIFEEAKFKDSS
::::::::: :::::::::::::::::::::::::
XP_011 EDPPIGAEQ--------------------------QLSGVNAVMFYAETIFEEAKFKDSS
100 110 120 130
300 310 320 330 340 350
pF1KE6 LASVVVGVIQVLFTAVAALIMDRAGRRLLLVLSGVVMVFSTSAFGAYFKLTQGGPGNSSH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 LASVVVGVIQVLFTAVAALIMDRAGRRLLLVLSGVVMVFSTSAFGAYFKLTQGGPGNSSH
140 150 160 170 180 190
360 370 380 390 400 410
pF1KE6 VAISAPVSAQPVDASVGLAWLAVGSMCLFIAGFAVGWGPIPWLLMSEIFPLHVKGVATGI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 VAISAPVSAQPVDASVGLAWLAVGSMCLFIAGFAVGWGPIPWLLMSEIFPLHVKGVATGI
200 210 220 230 240 250
420 430 440 450 460 470
pF1KE6 CVLTNWLMAFLVTKEFSSLMEVLRPYGAFWLASAFCIFSVLFTLFCVPETKGKTLEQITA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 CVLTNWLMAFLVTKEFSSLMEVLRPYGAFWLASAFCIFSVLFTLFCVPETKGKTLEQITA
260 270 280 290 300 310
pF1KE6 HFEGR
:::::
XP_011 HFEGR
>>NP_060055 (OMIM: 606813) solute carrier family 2, faci (507 aa)
initn: 1150 init1: 709 opt: 885 Z-score: 895.3 bits: 175.1 E(85289): 3.9e-43
Smith-Waterman score: 1247; 43.7% identity (69.9% similar) in 492 aa overlap (6-477:17-502)
10 20 30 40
pF1KE6 MTPEDPEETQPLLGPPGGSAPRG----RRVFLAAFAAALGPLSFGFALG
::. : :: : : .:::::.:::.:: .:::.::
NP_060 MQEPLLGAEGPDYDTFPEKPPP---SPGDRARVGTLQNKRVFLATFAAVLGNFSFGYALV
10 20 30 40 50
50 60 70 80 90 100
pF1KE6 YSSPAIPSLQRAAPPAPRLDDAAASWFGAVVTLGAAAGGVLGGWLVDRAGRKLSLLLCSV
:.::.::.:.:. : .: . :::::.: ::::::::. . : : :::::... .:
NP_060 YTSPVIPALERSLDPDLHLTKSQASWFGSVFTLGAAAGGLSAMILNDLLGRKLSIMFSAV
60 70 80 90 100 110
110 120 130 140 150 160
pF1KE6 PFVAGFAVITAAQDVWMLLGGRLLTGLACGVASLVAPVYISEIAYPAVRGLLGSCVQLMV
: .::.:....:. .:::: :: :::.: :... :::.:::: :.::: ::. :::.
NP_060 PSAAGYALMAGAHGLWMLLLGRTLTGFAGGLTAACIPVYVSEIAPPGVRGALGATPQLMA
120 130 140 150 160 170
170 180 190 200 210 220
pF1KE6 VVGILLAYLAGWVLEWRWLAVLGCVPPSLMLLLMCFMPETPRFLLTQHRRQEAMAALRFL
: : : : : .: :::::: : .: .:.::. :::..:::::.. : .::. :: .:
NP_060 VFGSLSLYALGLLLPWRWLAVAGEAPVLIMILLLSFMPNSPRFLLSRGRDEEALRALAWL
180 190 200 210 220 230
230 240 250 260 270
pF1KE6 WGSEQG--WEDPPIGAE---QSFHL--ALLRQPGIYKPFIIGVSLMAFQQLSGVNAVMFY
:.. :: : . :: .. : : : . .:. ... . .:::.:.. .. :
NP_060 RGTDVDVHWEFEQIQDNVRRQSSRVSWAEARAPHVCRPITVALLMRLLQQLTGITPILVY
240 250 260 270 280 290
280 290 300 310 320 330
pF1KE6 AETIFEE-AKFKDSSLASVVVGVIQVLFTAVAALIMDRAGRRLLLVLSGVVMVFSTSAFG
..::. : . . ...::....: . .::: :: :::..:: .:...: .. ..:
NP_060 LQSIFDSTAVLLPPKDDAAIVGAVRLLSVLIAALTMDLAGRKVLLFVSAAIMFAANLTLG
300 310 320 330 340 350
340 350 360 370 380 390
pF1KE6 AY--FKLTQGGPGNSSHV-AISAPVSAQPVDASVG-LAWLAVGSMCLFIAGFAVGWGPIP
: : .:.... . . : :::. : .: :. . . . ::: :.:::::::
NP_060 LYIHFGPRPLSPNSTAGLESESWGDLAQPLAAPAGYLTLVPLLATMLFIMGYAVGWGPIT
360 370 380 390 400 410
400 410 420 430 440 450
pF1KE6 WLLMSEIFPLHVKGVATGICVLTNWLMAFLVTKEFSSLMEVLRPYG---AFWLASAFCIF
::::::..::...:::.:.:::..:: ::..:: : . :. .: :.. .:.:.
NP_060 WLLMSEVLPLRARGVASGLCVLASWLTAFVLTKSF---LPVVSTFGLQVPFFFFAAICLV
420 430 440 450 460 470
460 470
pF1KE6 SVLFTLFCVPETKGKTLEQITAHFE-GR
:..:: :::::::..:::: . :. ::
NP_060 SLVFTGCCVPETKGRSLEQIESFFRTGRRSFLR
480 490 500
>>NP_001138571 (OMIM: 606813) solute carrier family 2, f (445 aa)
initn: 1155 init1: 709 opt: 872 Z-score: 883.0 bits: 172.7 E(85289): 1.9e-42
Smith-Waterman score: 1100; 41.0% identity (63.5% similar) in 488 aa overlap (6-477:17-440)
10 20 30 40
pF1KE6 MTPEDPEETQPLLGPPGGSAPRG----RRVFLAAFAAALGPLSFGFALG
::. : :: : : .:::::.:::.:: .:::.::
NP_001 MQEPLLGAEGPDYDTFPEKPPP---SPGDRARVGTLQNKRVFLATFAAVLGNFSFGYALV
10 20 30 40 50
50 60 70 80 90 100
pF1KE6 YSSPAIPSLQRAAPPAPRLDDAAASWFGAVVTLGAAAGGVLGGWLVDRAGRKLSLLLCSV
:.::.::.:.:. : .: . :::::.: ::::::::. . : : :::::... .:
NP_001 YTSPVIPALERSLDPDLHLTKSQASWFGSVFTLGAAAGGLSAMILNDLLGRKLSIMFSAV
60 70 80 90 100 110
110 120 130 140 150 160
pF1KE6 PFVAGFAVITAAQDVWMLLGGRLLTGLACGVASLVAPVYISEIAYPAVRGLLGSCVQLMV
: .::.:....:. .:::: :: :::.: :... :::.:::: :.::: ::. :::.
NP_001 PSAAGYALMAGAHGLWMLLLGRTLTGFAGGLTAACIPVYVSEIAPPGVRGALGATPQLMA
120 130 140 150 160 170
170 180 190 200 210 220
pF1KE6 VVGILLAYLAGWVLEWRWLAVLGCVPPSLMLLLMCFMPETPRFLLTQHRRQEAMAALRFL
: : : : : .: :::::: : .: .:.::. :::..:::::.. : .::. :: .:
NP_001 VFGSLSLYALGLLLPWRWLAVAGEAPVLIMILLLSFMPNSPRFLLSRGRDEEALRALAWL
180 190 200 210 220 230
230 240 250 260 270
pF1KE6 WGSEQG--WEDPPIGAE---QSFHL--ALLRQPGIYKPFIIGVSLMAFQQLSGVNAVMFY
:.. :: : . :: .. : : : . .:. ... . .:::.:.. .. :
NP_001 RGTDVDVHWEFEQIQDNVRRQSSRVSWAEARAPHVCRPITVALLMRLLQQLTGITPILVY
240 250 260 270 280 290
280 290 300 310 320 330
pF1KE6 AETIFEE-AKFKDSSLASVVVGVIQVLFTAVAALIMDRAGRRLLLVLSGVVMVFSTSAFG
..::. : . . ...::....: . .::: :: :::..::
NP_001 LQSIFDSTAVLLPPKDDAAIVGAVRLLSVLIAALTMDLAGRKVLL---------------
300 310 320 330 340
340 350 360 370 380 390
pF1KE6 AYFKLTQGGPGNSSHVAISAPVSAQPVDASVGLAWLAVGSMCLFIAGFAVGWGPIPWLLM
:..:.::::::: ::::
NP_001 -------------------------------------------FVSGYAVGWGPITWLLM
350
400 410 420 430 440 450
pF1KE6 SEIFPLHVKGVATGICVLTNWLMAFLVTKEFSSLMEVLRPYG---AFWLASAFCIFSVLF
::..::...:::.:.:::..:: ::..:: : . :. .: :.. .:.:. :..:
NP_001 SEVLPLRARGVASGLCVLASWLTAFVLTKSF---LPVVSTFGLQVPFFFFAAICLVSLVF
360 370 380 390 400 410
460 470
pF1KE6 TLFCVPETKGKTLEQITAHFE-GR
: :::::::..:::: . :. ::
NP_001 TGCCVPETKGRSLEQIESFFRTGRRSFLR
420 430 440
477 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Nov 8 12:54:54 2016 done: Tue Nov 8 12:54:56 2016
Total Scan time: 7.930 Total Display time: 0.030
Function used was FASTA [36.3.4 Apr, 2011]