Result of FASTA (omim) for
pFN21AE6397
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE6397, 223 aa
1>>>pF1KE6397 223 - 223 aa - 223 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 9.6535+/-0.000338; mu= -5.2680+/- 0.021
mean_var=224.8273+/-46.557, 0's: 0 Z-trim(122.6): 7 B-trim: 0 in 0/57
Lambda= 0.085536
statistics sampled from 40999 (41006) to 40999 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.803), E-opt: 0.2 (0.481), width: 16
Scan time: 4.770
The best scores are: opt bits E(85289)
XP_005250568 (OMIM: 615203) PREDICTED: rhomboid do ( 223) 1525 199.9 2.9e-51
NP_001333116 (OMIM: 615203) rhomboid domain-contai ( 223) 1525 199.9 2.9e-51
NP_001333115 (OMIM: 615203) rhomboid domain-contai ( 223) 1525 199.9 2.9e-51
NP_001035547 (OMIM: 615203) rhomboid domain-contai ( 223) 1525 199.9 2.9e-51
NP_001035546 (OMIM: 615203) rhomboid domain-contai ( 364) 1525 200.0 4.3e-51
NP_001333117 (OMIM: 615203) rhomboid domain-contai ( 228) 1165 155.5 6.9e-38
NP_001333118 (OMIM: 615203) rhomboid domain-contai ( 216) 1090 146.2 4e-35
>>XP_005250568 (OMIM: 615203) PREDICTED: rhomboid domain (223 aa)
initn: 1525 init1: 1525 opt: 1525 Z-score: 1041.5 bits: 199.9 E(85289): 2.9e-51
Smith-Waterman score: 1525; 100.0% identity (100.0% similar) in 223 aa overlap (1-223:1-223)
10 20 30 40 50 60
pF1KE6 MLGVTTVRSRMRRALVFGMVVPSVLVPWLLLGASWLIPQTSFLSNVCGLSIGLAYGLTYC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MLGVTTVRSRMRRALVFGMVVPSVLVPWLLLGASWLIPQTSFLSNVCGLSIGLAYGLTYC
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 YSIDLSERVALKLDQTFPFSLMRRISVFKYVSGSSAERRAAQSRKLNPVPGSYPTQSCHP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 YSIDLSERVALKLDQTFPFSLMRRISVFKYVSGSSAERRAAQSRKLNPVPGSYPTQSCHP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 HLSPSHPVSQTQHASGQKLASWPSCTPGHMPTLPPYQPASGLCYVQNHFGPNPTSSSVYP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 HLSPSHPVSQTQHASGQKLASWPSCTPGHMPTLPPYQPASGLCYVQNHFGPNPTSSSVYP
130 140 150 160 170 180
190 200 210 220
pF1KE6 ASAGTSLGIQPPTPVNSPGTVYSGALGTPGAAGSKESSRVPMP
:::::::::::::::::::::::::::::::::::::::::::
XP_005 ASAGTSLGIQPPTPVNSPGTVYSGALGTPGAAGSKESSRVPMP
190 200 210 220
>>NP_001333116 (OMIM: 615203) rhomboid domain-containing (223 aa)
initn: 1525 init1: 1525 opt: 1525 Z-score: 1041.5 bits: 199.9 E(85289): 2.9e-51
Smith-Waterman score: 1525; 100.0% identity (100.0% similar) in 223 aa overlap (1-223:1-223)
10 20 30 40 50 60
pF1KE6 MLGVTTVRSRMRRALVFGMVVPSVLVPWLLLGASWLIPQTSFLSNVCGLSIGLAYGLTYC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MLGVTTVRSRMRRALVFGMVVPSVLVPWLLLGASWLIPQTSFLSNVCGLSIGLAYGLTYC
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 YSIDLSERVALKLDQTFPFSLMRRISVFKYVSGSSAERRAAQSRKLNPVPGSYPTQSCHP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YSIDLSERVALKLDQTFPFSLMRRISVFKYVSGSSAERRAAQSRKLNPVPGSYPTQSCHP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 HLSPSHPVSQTQHASGQKLASWPSCTPGHMPTLPPYQPASGLCYVQNHFGPNPTSSSVYP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HLSPSHPVSQTQHASGQKLASWPSCTPGHMPTLPPYQPASGLCYVQNHFGPNPTSSSVYP
130 140 150 160 170 180
190 200 210 220
pF1KE6 ASAGTSLGIQPPTPVNSPGTVYSGALGTPGAAGSKESSRVPMP
:::::::::::::::::::::::::::::::::::::::::::
NP_001 ASAGTSLGIQPPTPVNSPGTVYSGALGTPGAAGSKESSRVPMP
190 200 210 220
>>NP_001333115 (OMIM: 615203) rhomboid domain-containing (223 aa)
initn: 1525 init1: 1525 opt: 1525 Z-score: 1041.5 bits: 199.9 E(85289): 2.9e-51
Smith-Waterman score: 1525; 100.0% identity (100.0% similar) in 223 aa overlap (1-223:1-223)
10 20 30 40 50 60
pF1KE6 MLGVTTVRSRMRRALVFGMVVPSVLVPWLLLGASWLIPQTSFLSNVCGLSIGLAYGLTYC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MLGVTTVRSRMRRALVFGMVVPSVLVPWLLLGASWLIPQTSFLSNVCGLSIGLAYGLTYC
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 YSIDLSERVALKLDQTFPFSLMRRISVFKYVSGSSAERRAAQSRKLNPVPGSYPTQSCHP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YSIDLSERVALKLDQTFPFSLMRRISVFKYVSGSSAERRAAQSRKLNPVPGSYPTQSCHP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 HLSPSHPVSQTQHASGQKLASWPSCTPGHMPTLPPYQPASGLCYVQNHFGPNPTSSSVYP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HLSPSHPVSQTQHASGQKLASWPSCTPGHMPTLPPYQPASGLCYVQNHFGPNPTSSSVYP
130 140 150 160 170 180
190 200 210 220
pF1KE6 ASAGTSLGIQPPTPVNSPGTVYSGALGTPGAAGSKESSRVPMP
:::::::::::::::::::::::::::::::::::::::::::
NP_001 ASAGTSLGIQPPTPVNSPGTVYSGALGTPGAAGSKESSRVPMP
190 200 210 220
>>NP_001035547 (OMIM: 615203) rhomboid domain-containing (223 aa)
initn: 1525 init1: 1525 opt: 1525 Z-score: 1041.5 bits: 199.9 E(85289): 2.9e-51
Smith-Waterman score: 1525; 100.0% identity (100.0% similar) in 223 aa overlap (1-223:1-223)
10 20 30 40 50 60
pF1KE6 MLGVTTVRSRMRRALVFGMVVPSVLVPWLLLGASWLIPQTSFLSNVCGLSIGLAYGLTYC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MLGVTTVRSRMRRALVFGMVVPSVLVPWLLLGASWLIPQTSFLSNVCGLSIGLAYGLTYC
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 YSIDLSERVALKLDQTFPFSLMRRISVFKYVSGSSAERRAAQSRKLNPVPGSYPTQSCHP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YSIDLSERVALKLDQTFPFSLMRRISVFKYVSGSSAERRAAQSRKLNPVPGSYPTQSCHP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 HLSPSHPVSQTQHASGQKLASWPSCTPGHMPTLPPYQPASGLCYVQNHFGPNPTSSSVYP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 HLSPSHPVSQTQHASGQKLASWPSCTPGHMPTLPPYQPASGLCYVQNHFGPNPTSSSVYP
130 140 150 160 170 180
190 200 210 220
pF1KE6 ASAGTSLGIQPPTPVNSPGTVYSGALGTPGAAGSKESSRVPMP
:::::::::::::::::::::::::::::::::::::::::::
NP_001 ASAGTSLGIQPPTPVNSPGTVYSGALGTPGAAGSKESSRVPMP
190 200 210 220
>>NP_001035546 (OMIM: 615203) rhomboid domain-containing (364 aa)
initn: 1525 init1: 1525 opt: 1525 Z-score: 1038.3 bits: 200.0 E(85289): 4.3e-51
Smith-Waterman score: 1525; 100.0% identity (100.0% similar) in 223 aa overlap (1-223:142-364)
10 20 30
pF1KE6 MLGVTTVRSRMRRALVFGMVVPSVLVPWLL
::::::::::::::::::::::::::::::
NP_001 IIFLSFEAVSSLSKLGEVEDARGFTPVAFAMLGVTTVRSRMRRALVFGMVVPSVLVPWLL
120 130 140 150 160 170
40 50 60 70 80 90
pF1KE6 LGASWLIPQTSFLSNVCGLSIGLAYGLTYCYSIDLSERVALKLDQTFPFSLMRRISVFKY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LGASWLIPQTSFLSNVCGLSIGLAYGLTYCYSIDLSERVALKLDQTFPFSLMRRISVFKY
180 190 200 210 220 230
100 110 120 130 140 150
pF1KE6 VSGSSAERRAAQSRKLNPVPGSYPTQSCHPHLSPSHPVSQTQHASGQKLASWPSCTPGHM
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VSGSSAERRAAQSRKLNPVPGSYPTQSCHPHLSPSHPVSQTQHASGQKLASWPSCTPGHM
240 250 260 270 280 290
160 170 180 190 200 210
pF1KE6 PTLPPYQPASGLCYVQNHFGPNPTSSSVYPASAGTSLGIQPPTPVNSPGTVYSGALGTPG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PTLPPYQPASGLCYVQNHFGPNPTSSSVYPASAGTSLGIQPPTPVNSPGTVYSGALGTPG
300 310 320 330 340 350
220
pF1KE6 AAGSKESSRVPMP
:::::::::::::
NP_001 AAGSKESSRVPMP
360
>>NP_001333117 (OMIM: 615203) rhomboid domain-containing (228 aa)
initn: 1165 init1: 1165 opt: 1165 Z-score: 801.2 bits: 155.5 E(85289): 6.9e-38
Smith-Waterman score: 1165; 100.0% identity (100.0% similar) in 168 aa overlap (56-223:61-228)
30 40 50 60 70 80
pF1KE6 VPWLLLGASWLIPQTSFLSNVCGLSIGLAYGLTYCYSIDLSERVALKLDQTFPFSLMRRI
::::::::::::::::::::::::::::::
NP_001 VSGPRLFLLQQPLAPSGLTLKSEALRNWQDGLTYCYSIDLSERVALKLDQTFPFSLMRRI
40 50 60 70 80 90
90 100 110 120 130 140
pF1KE6 SVFKYVSGSSAERRAAQSRKLNPVPGSYPTQSCHPHLSPSHPVSQTQHASGQKLASWPSC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SVFKYVSGSSAERRAAQSRKLNPVPGSYPTQSCHPHLSPSHPVSQTQHASGQKLASWPSC
100 110 120 130 140 150
150 160 170 180 190 200
pF1KE6 TPGHMPTLPPYQPASGLCYVQNHFGPNPTSSSVYPASAGTSLGIQPPTPVNSPGTVYSGA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TPGHMPTLPPYQPASGLCYVQNHFGPNPTSSSVYPASAGTSLGIQPPTPVNSPGTVYSGA
160 170 180 190 200 210
210 220
pF1KE6 LGTPGAAGSKESSRVPMP
::::::::::::::::::
NP_001 LGTPGAAGSKESSRVPMP
220
>>NP_001333118 (OMIM: 615203) rhomboid domain-containing (216 aa)
initn: 1090 init1: 1090 opt: 1090 Z-score: 751.6 bits: 146.2 E(85289): 4e-35
Smith-Waterman score: 1090; 100.0% identity (100.0% similar) in 157 aa overlap (67-223:60-216)
40 50 60 70 80 90
pF1KE6 IPQTSFLSNVCGLSIGLAYGLTYCYSIDLSERVALKLDQTFPFSLMRRISVFKYVSGSSA
::::::::::::::::::::::::::::::
NP_001 LVSGPRLFLLQQPLAPSGLTLKSEALRNWQERVALKLDQTFPFSLMRRISVFKYVSGSSA
30 40 50 60 70 80
100 110 120 130 140 150
pF1KE6 ERRAAQSRKLNPVPGSYPTQSCHPHLSPSHPVSQTQHASGQKLASWPSCTPGHMPTLPPY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ERRAAQSRKLNPVPGSYPTQSCHPHLSPSHPVSQTQHASGQKLASWPSCTPGHMPTLPPY
90 100 110 120 130 140
160 170 180 190 200 210
pF1KE6 QPASGLCYVQNHFGPNPTSSSVYPASAGTSLGIQPPTPVNSPGTVYSGALGTPGAAGSKE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QPASGLCYVQNHFGPNPTSSSVYPASAGTSLGIQPPTPVNSPGTVYSGALGTPGAAGSKE
150 160 170 180 190 200
220
pF1KE6 SSRVPMP
:::::::
NP_001 SSRVPMP
210
223 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Nov 8 12:43:12 2016 done: Tue Nov 8 12:43:12 2016
Total Scan time: 4.770 Total Display time: -0.020
Function used was FASTA [36.3.4 Apr, 2011]