Result of FASTA (omim) for
pFN21AE6383
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE6383, 329 aa
1>>>pF1KE6383 329 - 329 aa - 329 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.1587+/-0.000332; mu= 17.1097+/- 0.021
mean_var=68.2713+/-13.783, 0's: 0 Z-trim(114.8): 16 B-trim: 270 in 1/52
Lambda= 0.155223
statistics sampled from 24784 (24797) to 24784 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.668), E-opt: 0.2 (0.291), width: 16
Scan time: 6.280
The best scores are: opt bits E(85289)
NP_001032728 (OMIM: 607858) presenilins-associated ( 329) 2285 520.5 1.9e-147
XP_016862290 (OMIM: 607858) PREDICTED: presenilins ( 344) 2015 460.1 3.1e-129
NP_001311366 (OMIM: 607858) presenilins-associated ( 295) 1584 363.5 3.1e-100
XP_016862291 (OMIM: 607858) PREDICTED: presenilins ( 310) 1583 363.3 3.8e-100
NP_001311367 (OMIM: 607858) presenilins-associated ( 283) 1437 330.6 2.4e-90
NP_001311365 (OMIM: 607858) presenilins-associated ( 345) 1437 330.6 2.9e-90
XP_016862289 (OMIM: 607858) PREDICTED: presenilins ( 360) 1437 330.6 3e-90
NP_061092 (OMIM: 607858) presenilins-associated rh ( 379) 1437 330.7 3.1e-90
XP_005247639 (OMIM: 607858) PREDICTED: presenilins ( 394) 1437 330.7 3.2e-90
XP_016862292 (OMIM: 607858) PREDICTED: presenilins ( 153) 657 155.7 5.7e-38
>>NP_001032728 (OMIM: 607858) presenilins-associated rho (329 aa)
initn: 2285 init1: 2285 opt: 2285 Z-score: 2768.2 bits: 520.5 E(85289): 1.9e-147
Smith-Waterman score: 2285; 100.0% identity (100.0% similar) in 329 aa overlap (1-329:1-329)
10 20 30 40 50 60
pF1KE6 MAWRGWAQRGWGCGQAWGASVGGRSCEELTAVLTPPQLLGRRFNFFIQQKCGFRKAPRKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MAWRGWAQRGWGCGQAWGASVGGRSCEELTAVLTPPQLLGRRFNFFIQQKCGFRKAPRKV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 EPRRSDPGTSGEAYKRSALIPPVEETVFYPSPYPIRSLIKPLFFTVGFTGCAFGSAAIWQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EPRRSDPGTSGEAYKRSALIPPVEETVFYPSPYPIRSLIKPLFFTVGFTGCAFGSAAIWQ
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 YESLKSRVQSYFDGIKADWLDSIRPQKEGDFRKEINKWWNNLSDGQRTVTGIIAANVLVF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YESLKSRVQSYFDGIKADWLDSIRPQKEGDFRKEINKWWNNLSDGQRTVTGIIAANVLVF
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE6 CLWRVPSLQRTMIRYFTSNPASSVISNFVSYVGKVATGRYGPSLGASGAIMTVLAAVCTK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CLWRVPSLQRTMIRYFTSNPASSVISNFVSYVGKVATGRYGPSLGASGAIMTVLAAVCTK
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE6 IPEGRLAIIFLPMFTFTAGNALKAIIAMDTAGMILGWKFFDHAAHLGGALFGIWYVTYGH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IPEGRLAIIFLPMFTFTAGNALKAIIAMDTAGMILGWKFFDHAAHLGGALFGIWYVTYGH
250 260 270 280 290 300
310 320
pF1KE6 ELIWKNREPLVKIWHEIRTNGPKKGGGSK
:::::::::::::::::::::::::::::
NP_001 ELIWKNREPLVKIWHEIRTNGPKKGGGSK
310 320
>>XP_016862290 (OMIM: 607858) PREDICTED: presenilins-ass (344 aa)
initn: 2060 init1: 2015 opt: 2015 Z-score: 2441.1 bits: 460.1 E(85289): 3.1e-129
Smith-Waterman score: 2015; 99.7% identity (100.0% similar) in 293 aa overlap (1-293:1-293)
10 20 30 40 50 60
pF1KE6 MAWRGWAQRGWGCGQAWGASVGGRSCEELTAVLTPPQLLGRRFNFFIQQKCGFRKAPRKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MAWRGWAQRGWGCGQAWGASVGGRSCEELTAVLTPPQLLGRRFNFFIQQKCGFRKAPRKV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 EPRRSDPGTSGEAYKRSALIPPVEETVFYPSPYPIRSLIKPLFFTVGFTGCAFGSAAIWQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EPRRSDPGTSGEAYKRSALIPPVEETVFYPSPYPIRSLIKPLFFTVGFTGCAFGSAAIWQ
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 YESLKSRVQSYFDGIKADWLDSIRPQKEGDFRKEINKWWNNLSDGQRTVTGIIAANVLVF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YESLKSRVQSYFDGIKADWLDSIRPQKEGDFRKEINKWWNNLSDGQRTVTGIIAANVLVF
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE6 CLWRVPSLQRTMIRYFTSNPASSVISNFVSYVGKVATGRYGPSLGASGAIMTVLAAVCTK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CLWRVPSLQRTMIRYFTSNPASSVISNFVSYVGKVATGRYGPSLGASGAIMTVLAAVCTK
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE6 IPEGRLAIIFLPMFTFTAGNALKAIIAMDTAGMILGWKFFDHAAHLGGALFGIWYVTYGH
::::::::::::::::::::::::::::::::::::::::::::::::::::.
XP_016 IPEGRLAIIFLPMFTFTAGNALKAIIAMDTAGMILGWKFFDHAAHLGGALFGMISLYTWR
250 260 270 280 290 300
310 320
pF1KE6 ELIWKNREPLVKIWHEIRTNGPKKGGGSK
XP_016 LACCLLGHGLACSADLLPLLGSRHVTLLQLQAKTGNVLGDESVF
310 320 330 340
>>NP_001311366 (OMIM: 607858) presenilins-associated rho (295 aa)
initn: 1602 init1: 1582 opt: 1584 Z-score: 1920.5 bits: 363.5 E(85289): 3.1e-100
Smith-Waterman score: 1991; 89.7% identity (89.7% similar) in 329 aa overlap (1-329:1-295)
10 20 30 40 50 60
pF1KE6 MAWRGWAQRGWGCGQAWGASVGGRSCEELTAVLTPPQLLGRRFNFFIQQKCGFRKAPRKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MAWRGWAQRGWGCGQAWGASVGGRSCEELTAVLTPPQLLGRRFNFFIQQKCGFRKAPRKV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 EPRRSDPGTSGEAYKRSALIPPVEETVFYPSPYPIRSLIKPLFFTVGFTGCAFGSAAIWQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EPRRSDPGTSGEAYKRSALIPPVEETVFYPSPYPIRSLIKPLFFTVGFTGCAFGSAAIWQ
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 YESLKSRVQSYFDGIKADWLDSIRPQKEGDFRKEINKWWNNLSDGQRTVTGIIAANVLVF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YESLKSRVQSYFDGIKADWLDSIRPQKEGDFRKEINKWWNNLSDGQRTVTGIIAANVLVF
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE6 CLWRVPSLQRTMIRYFTSNPASSVISNFVSYVGKVATGRYGPSLGASGAIMTVLAAVCTK
::::::::::::::::::::::::::::::::::::::::::::::
NP_001 CLWRVPSLQRTMIRYFTSNPASSVISNFVSYVGKVATGRYGPSLGA--------------
190 200 210 220
250 260 270 280 290 300
pF1KE6 IPEGRLAIIFLPMFTFTAGNALKAIIAMDTAGMILGWKFFDHAAHLGGALFGIWYVTYGH
::::::::::::::::::::::::::::::::::::::::
NP_001 --------------------ALKAIIAMDTAGMILGWKFFDHAAHLGGALFGIWYVTYGH
230 240 250 260
310 320
pF1KE6 ELIWKNREPLVKIWHEIRTNGPKKGGGSK
:::::::::::::::::::::::::::::
NP_001 ELIWKNREPLVKIWHEIRTNGPKKGGGSK
270 280 290
>>XP_016862291 (OMIM: 607858) PREDICTED: presenilins-ass (310 aa)
initn: 1786 init1: 1582 opt: 1583 Z-score: 1919.0 bits: 363.3 E(85289): 3.8e-100
Smith-Waterman score: 1721; 88.1% identity (88.4% similar) in 293 aa overlap (1-293:1-259)
10 20 30 40 50 60
pF1KE6 MAWRGWAQRGWGCGQAWGASVGGRSCEELTAVLTPPQLLGRRFNFFIQQKCGFRKAPRKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MAWRGWAQRGWGCGQAWGASVGGRSCEELTAVLTPPQLLGRRFNFFIQQKCGFRKAPRKV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 EPRRSDPGTSGEAYKRSALIPPVEETVFYPSPYPIRSLIKPLFFTVGFTGCAFGSAAIWQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EPRRSDPGTSGEAYKRSALIPPVEETVFYPSPYPIRSLIKPLFFTVGFTGCAFGSAAIWQ
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 YESLKSRVQSYFDGIKADWLDSIRPQKEGDFRKEINKWWNNLSDGQRTVTGIIAANVLVF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YESLKSRVQSYFDGIKADWLDSIRPQKEGDFRKEINKWWNNLSDGQRTVTGIIAANVLVF
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE6 CLWRVPSLQRTMIRYFTSNPASSVISNFVSYVGKVATGRYGPSLGASGAIMTVLAAVCTK
::::::::::::::::::::::::::::::::::::::::::::::
XP_016 CLWRVPSLQRTMIRYFTSNPASSVISNFVSYVGKVATGRYGPSLGA--------------
190 200 210 220
250 260 270 280 290 300
pF1KE6 IPEGRLAIIFLPMFTFTAGNALKAIIAMDTAGMILGWKFFDHAAHLGGALFGIWYVTYGH
::::::::::::::::::::::::::::::::.
XP_016 --------------------ALKAIIAMDTAGMILGWKFFDHAAHLGGALFGMISLYTWR
230 240 250 260
310 320
pF1KE6 ELIWKNREPLVKIWHEIRTNGPKKGGGSK
XP_016 LACCLLGHGLACSADLLPLLGSRHVTLLQLQAKTGNVLGDESVF
270 280 290 300 310
>>NP_001311367 (OMIM: 607858) presenilins-associated rho (283 aa)
initn: 1482 init1: 1437 opt: 1437 Z-score: 1742.8 bits: 330.6 E(85289): 2.4e-90
Smith-Waterman score: 1466; 81.5% identity (81.9% similar) in 276 aa overlap (1-226:1-276)
10 20 30 40 50 60
pF1KE6 MAWRGWAQRGWGCGQAWGASVGGRSCEELTAVLTPPQLLGRRFNFFIQQKCGFRKAPRKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MAWRGWAQRGWGCGQAWGASVGGRSCEELTAVLTPPQLLGRRFNFFIQQKCGFRKAPRKV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 EPRRSDPGTSGEAYKRSALIPPVEETVFYPSPYPIRSLIKPLFFTVGFTGCAFGSAAIWQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EPRRSDPGTSGEAYKRSALIPPVEETVFYPSPYPIRSLIKPLFFTVGFTGCAFGSAAIWQ
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 YESLKSRVQSYFDGIKADWLDSIRPQKEGDFRKEINKWWNNLSDGQRTVTGIIAANVLVF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YESLKSRVQSYFDGIKADWLDSIRPQKEGDFRKEINKWWNNLSDGQRTVTGIIAANVLVF
130 140 150 160 170 180
190 200
pF1KE6 CLWRVPSLQRTMIRYFTSNPASSV------------------------------------
::::::::::::::::::::::.:
NP_001 CLWRVPSLQRTMIRYFTSNPASKVLCSPMLLSTFSHFSLFHMAANMYVLWSFSSSIVNIL
190 200 210 220 230 240
210 220 230 240 250
pF1KE6 --------------ISNFVSYVGKVATGRYGPSLGASGAIMTVLAAVCTKIPEGRLAIIF
::::::::::::::::::::::
NP_001 GQEQFMAVYLSAGVISNFVSYVGKVATGRYGPSLGAMVCYLRS
250 260 270 280
260 270 280 290 300 310
pF1KE6 LPMFTFTAGNALKAIIAMDTAGMILGWKFFDHAAHLGGALFGIWYVTYGHELIWKNREPL
>>NP_001311365 (OMIM: 607858) presenilins-associated rho (345 aa)
initn: 1938 init1: 1437 opt: 1437 Z-score: 1741.6 bits: 330.6 E(85289): 2.9e-90
Smith-Waterman score: 1879; 81.7% identity (87.5% similar) in 345 aa overlap (1-329:1-345)
10 20 30 40 50 60
pF1KE6 MAWRGWAQRGWGCGQAWGASVGGRSCEELTAVLTPPQLLGRRFNFFIQQKCGFRKAPRKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MAWRGWAQRGWGCGQAWGASVGGRSCEELTAVLTPPQLLGRRFNFFIQQKCGFRKAPRKV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 EPRRSDPGTSGEAYKRSALIPPVEETVFYPSPYPIRSLIKPLFFTVGFTGCAFGSAAIWQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EPRRSDPGTSGEAYKRSALIPPVEETVFYPSPYPIRSLIKPLFFTVGFTGCAFGSAAIWQ
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 YESLKSRVQSYFDGIKADWLDSIRPQKEGDFRKEINKWWNNLSDGQRTVTGIIAANVLVF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YESLKSRVQSYFDGIKADWLDSIRPQKEGDFRKEINKWWNNLSDGQRTVTGIIAANVLVF
130 140 150 160 170 180
190 200 210 220
pF1KE6 CLWRVPSLQRTMIRYFTSNPASSVI------SNFVSY-VGKVATGRY-----GPS----L
::::::::::::::::::::::.:. :.: . . ..:.. : . : :
NP_001 CLWRVPSLQRTMIRYFTSNPASKVLCSPMLLSTFSHFSLFHMAANMYVLWSFSSSIVNIL
190 200 210 220 230 240
230 240 250 260 270 280
pF1KE6 GASGAIMTVLAAVCTKIPEGRLAIIFLPMFTFTAGNALKAIIAMDTAGMILGWKFFDHAA
: . . :.: . . .. . . . : ::::::::::::::::::::::::
NP_001 GQEQFMAVYLSAGVISNFVSYVGKVATGRYGPSLGAALKAIIAMDTAGMILGWKFFDHAA
250 260 270 280 290 300
290 300 310 320
pF1KE6 HLGGALFGIWYVTYGHELIWKNREPLVKIWHEIRTNGPKKGGGSK
:::::::::::::::::::::::::::::::::::::::::::::
NP_001 HLGGALFGIWYVTYGHELIWKNREPLVKIWHEIRTNGPKKGGGSK
310 320 330 340
>>XP_016862289 (OMIM: 607858) PREDICTED: presenilins-ass (360 aa)
initn: 1668 init1: 1437 opt: 1437 Z-score: 1741.3 bits: 330.6 E(85289): 3e-90
Smith-Waterman score: 1609; 79.3% identity (86.1% similar) in 309 aa overlap (1-293:1-309)
10 20 30 40 50 60
pF1KE6 MAWRGWAQRGWGCGQAWGASVGGRSCEELTAVLTPPQLLGRRFNFFIQQKCGFRKAPRKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MAWRGWAQRGWGCGQAWGASVGGRSCEELTAVLTPPQLLGRRFNFFIQQKCGFRKAPRKV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 EPRRSDPGTSGEAYKRSALIPPVEETVFYPSPYPIRSLIKPLFFTVGFTGCAFGSAAIWQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 EPRRSDPGTSGEAYKRSALIPPVEETVFYPSPYPIRSLIKPLFFTVGFTGCAFGSAAIWQ
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 YESLKSRVQSYFDGIKADWLDSIRPQKEGDFRKEINKWWNNLSDGQRTVTGIIAANVLVF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YESLKSRVQSYFDGIKADWLDSIRPQKEGDFRKEINKWWNNLSDGQRTVTGIIAANVLVF
130 140 150 160 170 180
190 200 210 220
pF1KE6 CLWRVPSLQRTMIRYFTSNPASSVI------SNFVSY-VGKVATGRY-----GPS----L
::::::::::::::::::::::.:. :.: . . ..:.. : . : :
XP_016 CLWRVPSLQRTMIRYFTSNPASKVLCSPMLLSTFSHFSLFHMAANMYVLWSFSSSIVNIL
190 200 210 220 230 240
230 240 250 260 270 280
pF1KE6 GASGAIMTVLAAVCTKIPEGRLAIIFLPMFTFTAGNALKAIIAMDTAGMILGWKFFDHAA
: . . :.: . . .. . . . : ::::::::::::::::::::::::
XP_016 GQEQFMAVYLSAGVISNFVSYVGKVATGRYGPSLGAALKAIIAMDTAGMILGWKFFDHAA
250 260 270 280 290 300
290 300 310 320
pF1KE6 HLGGALFGIWYVTYGHELIWKNREPLVKIWHEIRTNGPKKGGGSK
::::::::.
XP_016 HLGGALFGMISLYTWRLACCLLGHGLACSADLLPLLGSRHVTLLQLQAKTGNVLGDESVF
310 320 330 340 350 360
>>NP_061092 (OMIM: 607858) presenilins-associated rhombo (379 aa)
initn: 1457 init1: 1437 opt: 1437 Z-score: 1741.0 bits: 330.7 E(85289): 3.1e-90
Smith-Waterman score: 2039; 85.9% identity (86.1% similar) in 361 aa overlap (1-311:1-361)
10 20 30 40 50 60
pF1KE6 MAWRGWAQRGWGCGQAWGASVGGRSCEELTAVLTPPQLLGRRFNFFIQQKCGFRKAPRKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 MAWRGWAQRGWGCGQAWGASVGGRSCEELTAVLTPPQLLGRRFNFFIQQKCGFRKAPRKV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 EPRRSDPGTSGEAYKRSALIPPVEETVFYPSPYPIRSLIKPLFFTVGFTGCAFGSAAIWQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 EPRRSDPGTSGEAYKRSALIPPVEETVFYPSPYPIRSLIKPLFFTVGFTGCAFGSAAIWQ
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 YESLKSRVQSYFDGIKADWLDSIRPQKEGDFRKEINKWWNNLSDGQRTVTGIIAANVLVF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 YESLKSRVQSYFDGIKADWLDSIRPQKEGDFRKEINKWWNNLSDGQRTVTGIIAANVLVF
130 140 150 160 170 180
190 200
pF1KE6 CLWRVPSLQRTMIRYFTSNPASSV------------------------------------
::::::::::::::::::::::.:
NP_061 CLWRVPSLQRTMIRYFTSNPASKVLCSPMLLSTFSHFSLFHMAANMYVLWSFSSSIVNIL
190 200 210 220 230 240
210 220 230 240 250
pF1KE6 --------------ISNFVSYVGKVATGRYGPSLGASGAIMTVLAAVCTKIPEGRLAIIF
::::::::::::::::::::::::::::::::::::::::::::::
NP_061 GQEQFMAVYLSAGVISNFVSYVGKVATGRYGPSLGASGAIMTVLAAVCTKIPEGRLAIIF
250 260 270 280 290 300
260 270 280 290 300 310
pF1KE6 LPMFTFTAGNALKAIIAMDTAGMILGWKFFDHAAHLGGALFGIWYVTYGHELIWKNREPL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_061 LPMFTFTAGNALKAIIAMDTAGMILGWKFFDHAAHLGGALFGIWYVTYGHELIWKNREPL
310 320 330 340 350 360
320
pF1KE6 VKIWHEIRTNGPKKGGGSK
:
NP_061 VKIWHEIRTNGPKKGGGSK
370
>>XP_005247639 (OMIM: 607858) PREDICTED: presenilins-ass (394 aa)
initn: 2023 init1: 1437 opt: 1437 Z-score: 1740.8 bits: 330.7 E(85289): 3.2e-90
Smith-Waterman score: 1900; 84.8% identity (85.4% similar) in 343 aa overlap (1-293:1-343)
10 20 30 40 50 60
pF1KE6 MAWRGWAQRGWGCGQAWGASVGGRSCEELTAVLTPPQLLGRRFNFFIQQKCGFRKAPRKV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 MAWRGWAQRGWGCGQAWGASVGGRSCEELTAVLTPPQLLGRRFNFFIQQKCGFRKAPRKV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 EPRRSDPGTSGEAYKRSALIPPVEETVFYPSPYPIRSLIKPLFFTVGFTGCAFGSAAIWQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 EPRRSDPGTSGEAYKRSALIPPVEETVFYPSPYPIRSLIKPLFFTVGFTGCAFGSAAIWQ
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 YESLKSRVQSYFDGIKADWLDSIRPQKEGDFRKEINKWWNNLSDGQRTVTGIIAANVLVF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_005 YESLKSRVQSYFDGIKADWLDSIRPQKEGDFRKEINKWWNNLSDGQRTVTGIIAANVLVF
130 140 150 160 170 180
190 200
pF1KE6 CLWRVPSLQRTMIRYFTSNPASSV------------------------------------
::::::::::::::::::::::.:
XP_005 CLWRVPSLQRTMIRYFTSNPASKVLCSPMLLSTFSHFSLFHMAANMYVLWSFSSSIVNIL
190 200 210 220 230 240
210 220 230 240 250
pF1KE6 --------------ISNFVSYVGKVATGRYGPSLGASGAIMTVLAAVCTKIPEGRLAIIF
::::::::::::::::::::::::::::::::::::::::::::::
XP_005 GQEQFMAVYLSAGVISNFVSYVGKVATGRYGPSLGASGAIMTVLAAVCTKIPEGRLAIIF
250 260 270 280 290 300
260 270 280 290 300 310
pF1KE6 LPMFTFTAGNALKAIIAMDTAGMILGWKFFDHAAHLGGALFGIWYVTYGHELIWKNREPL
::::::::::::::::::::::::::::::::::::::::::.
XP_005 LPMFTFTAGNALKAIIAMDTAGMILGWKFFDHAAHLGGALFGMISLYTWRLACCLLGHGL
310 320 330 340 350 360
320
pF1KE6 VKIWHEIRTNGPKKGGGSK
XP_005 ACSADLLPLLGSRHVTLLQLQAKTGNVLGDESVF
370 380 390
>>XP_016862292 (OMIM: 607858) PREDICTED: presenilins-ass (153 aa)
initn: 657 init1: 657 opt: 657 Z-score: 802.7 bits: 155.7 E(85289): 5.7e-38
Smith-Waterman score: 657; 99.0% identity (100.0% similar) in 102 aa overlap (192-293:1-102)
170 180 190 200 210 220
pF1KE6 LSDGQRTVTGIIAANVLVFCLWRVPSLQRTMIRYFTSNPASSVISNFVSYVGKVATGRYG
::::::::::::::::::::::::::::::
XP_016 MIRYFTSNPASSVISNFVSYVGKVATGRYG
10 20 30
230 240 250 260 270 280
pF1KE6 PSLGASGAIMTVLAAVCTKIPEGRLAIIFLPMFTFTAGNALKAIIAMDTAGMILGWKFFD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 PSLGASGAIMTVLAAVCTKIPEGRLAIIFLPMFTFTAGNALKAIIAMDTAGMILGWKFFD
40 50 60 70 80 90
290 300 310 320
pF1KE6 HAAHLGGALFGIWYVTYGHELIWKNREPLVKIWHEIRTNGPKKGGGSK
:::::::::::.
XP_016 HAAHLGGALFGMISLYTWRLACCLLGHGLACSADLLPLLGSRHVTLLQLQAKTGNVLGDE
100 110 120 130 140 150
329 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Nov 8 12:46:36 2016 done: Tue Nov 8 12:46:36 2016
Total Scan time: 6.280 Total Display time: 0.010
Function used was FASTA [36.3.4 Apr, 2011]