Result of FASTA (ccds) for
pFN21AE6378
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE6378, 307 aa
1>>>pF1KE6378 307 - 307 aa - 307 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.6350+/-0.00105; mu= 13.5271+/- 0.063
mean_var=62.5282+/-12.503, 0's: 0 Z-trim(102.8): 28 B-trim: 0 in 0/50
Lambda= 0.162195
statistics sampled from 7092 (7105) to 7092 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.606), E-opt: 0.2 (0.218), width: 16
Scan time: 2.070
The best scores are: opt bits E(32554)
CCDS3021.1 SEC22A gene_id:26984|Hs108|chr3 ( 307) 2054 489.5 1.4e-138
CCDS2700.1 SEC22C gene_id:9117|Hs108|chr3 ( 303) 757 186.0 3.2e-47
CCDS2699.1 SEC22C gene_id:9117|Hs108|chr3 ( 250) 554 138.4 5.3e-33
CCDS56246.1 SEC22C gene_id:9117|Hs108|chr3 ( 228) 510 128.1 6.1e-30
CCDS83523.1 SEC22B gene_id:9554|Hs108|chr1 ( 215) 350 90.7 1.1e-18
>>CCDS3021.1 SEC22A gene_id:26984|Hs108|chr3 (307 aa)
initn: 2054 init1: 2054 opt: 2054 Z-score: 2601.5 bits: 489.5 E(32554): 1.4e-138
Smith-Waterman score: 2054; 100.0% identity (100.0% similar) in 307 aa overlap (1-307:1-307)
10 20 30 40 50 60
pF1KE6 MSMILSASVIRVRDGLPLSASTDYEQSTGMQECRKYFKMLSRKLAQLPDRCTLKTGHYNI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS30 MSMILSASVIRVRDGLPLSASTDYEQSTGMQECRKYFKMLSRKLAQLPDRCTLKTGHYNI
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 NFISSLGVSYMMLCTENYPNVLAFSFLDELQKEFITTYNMMKTNTAVRPYCFIEFDNFIQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS30 NFISSLGVSYMMLCTENYPNVLAFSFLDELQKEFITTYNMMKTNTAVRPYCFIEFDNFIQ
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 RTKQRYNNPRSLSTKINLSDMQTEIKLRPPYQISMCELGSANGVTSAFSVDCKGAGKISS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS30 RTKQRYNNPRSLSTKINLSDMQTEIKLRPPYQISMCELGSANGVTSAFSVDCKGAGKISS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE6 AHQRLEPATLSGIVGFILSLLCGALNLIRGFHAIESLLQSDGDDFNYIIAFFLGTAACLY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS30 AHQRLEPATLSGIVGFILSLLCGALNLIRGFHAIESLLQSDGDDFNYIIAFFLGTAACLY
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE6 QCYLLVYYTGWRNVKSFLTFGLICLCNMYLYELRNLWQLFFHVTVGAFVTLQIWLRQAQG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS30 QCYLLVYYTGWRNVKSFLTFGLICLCNMYLYELRNLWQLFFHVTVGAFVTLQIWLRQAQG
250 260 270 280 290 300
pF1KE6 KAPDYDV
:::::::
CCDS30 KAPDYDV
>>CCDS2700.1 SEC22C gene_id:9117|Hs108|chr3 (303 aa)
initn: 796 init1: 408 opt: 757 Z-score: 961.4 bits: 186.0 E(32554): 3.2e-47
Smith-Waterman score: 757; 40.8% identity (68.3% similar) in 309 aa overlap (1-307:1-303)
10 20 30 40 50 60
pF1KE6 MSMILSASVIRVRDGLPLSASTDYEQSTGMQECRKYFKMLSRKLAQLPDRCTLKTGHYNI
::.:. : :.:::::::::::::. .. . : :. .: :. .::: : : . . ..:
CCDS27 MSVIFFACVVRVRDGLPLSASTDFYHTQDFLEWRRRLKSLALRLAQYPGRGSAEGCDFSI
10 20 30 40 50 60
70 80 90 100 110
pF1KE6 NFISSLG-VSYMMLCTENYPNVLAFSFLDELQKEFITTYNMMKTNTAVRPYCFIEFDNFI
.: ::.: :. : .:. . : ..:: ::. : :: ..:. . : ::: :.:::..:
CCDS27 HF-SSFGDVACMAICSCQCPAAMAFCFLETLWWEFTASYDTTCIGLASRPYAFLEFDSII
70 80 90 100 110
120 130 140 150 160 170
pF1KE6 QRTKQRYNNPRSLSTKINLSDMQTEIKLRPPYQISMCELGSANGVTSAFS-VDCKGAGKI
:..: ..: : . . .: .: :.::.:: ... . :::: .. . . . : ..
CCDS27 QKVKWHFNYVSSSQMECSLEKIQEELKLQPPAVLTLEDTDVANGVMNGHTPMHLEPAPNF
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE6 SSAHQRLEPATLSGIVGFILSLLCGALNLIRGFHAIESLLQSDGDDFNYIIAFFLGTAAC
:.::.: ::...::...:.::::::: : : :: .... :.::.. .::
CCDS27 -----RMEPVTALGILSLILNIMCAALNLIRGVHLAEHSLQVAHEEIGNILAFLVPFVAC
180 190 200 210 220 230
240 250 260 270 280 290
pF1KE6 LYQCYLLVYYTGWRNVKSFLTFGLICLCNMYLYELRNLWQLFFHVTVGAFVTLQIWLRQA
..:::: ..:. :..: : . .::: ::::. ::::::..::. :. . . :: ::
CCDS27 IFQCYLYLFYSPARTMKVVLMLLFICLGNMYLHGLRNLWQILFHIGVAFLSSYQILTRQL
240 250 260 270 280 290
300
pF1KE6 QGKAPDYDV
: : : :
CCDS27 QEKQSDCGV
300
>>CCDS2699.1 SEC22C gene_id:9117|Hs108|chr3 (250 aa)
initn: 561 init1: 408 opt: 554 Z-score: 706.0 bits: 138.4 E(32554): 5.3e-33
Smith-Waterman score: 554; 39.1% identity (68.3% similar) in 243 aa overlap (1-241:1-237)
10 20 30 40 50 60
pF1KE6 MSMILSASVIRVRDGLPLSASTDYEQSTGMQECRKYFKMLSRKLAQLPDRCTLKTGHYNI
::.:. : :.:::::::::::::. .. . : :. .: :. .::: : : . . ..:
CCDS26 MSVIFFACVVRVRDGLPLSASTDFYHTQDFLEWRRRLKSLALRLAQYPGRGSAEGCDFSI
10 20 30 40 50 60
70 80 90 100 110
pF1KE6 NFISSLG-VSYMMLCTENYPNVLAFSFLDELQKEFITTYNMMKTNTAVRPYCFIEFDNFI
.: ::.: :. : .:. . : ..:: ::. : :: ..:. . : ::: :.:::..:
CCDS26 HF-SSFGDVACMAICSCQCPAAMAFCFLETLWWEFTASYDTTCIGLASRPYAFLEFDSII
70 80 90 100 110
120 130 140 150 160 170
pF1KE6 QRTKQRYNNPRSLSTKINLSDMQTEIKLRPPYQISMCELGSANGVTSAFS-VDCKGAGKI
:..: ..: : . . .: .: :.::.:: ... . :::: .. . . . : ..
CCDS26 QKVKWHFNYVSSSQMECSLEKIQEELKLQPPAVLTLEDTDVANGVMNGHTPMHLEPAPNF
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE6 SSAHQRLEPATLSGIVGFILSLLCGALNLIRGFHAIESLLQSDGDDFNYIIAFFLGTAAC
:.::.: ::...::...:.::::::: : : :: .... :.::.. .::
CCDS26 -----RMEPVTALGILSLILNIMCAALNLIRGVHLAEHSLQVAHEEIGNILAFLVPFVAC
180 190 200 210 220 230
240 250 260 270 280 290
pF1KE6 LYQCYLLVYYTGWRNVKSFLTFGLICLCNMYLYELRNLWQLFFHVTVGAFVTLQIWLRQA
..:
CCDS26 IFQDPRSWFCWLDQTS
240 250
>>CCDS56246.1 SEC22C gene_id:9117|Hs108|chr3 (228 aa)
initn: 526 init1: 408 opt: 510 Z-score: 651.0 bits: 128.1 E(32554): 6.1e-30
Smith-Waterman score: 510; 39.1% identity (67.4% similar) in 230 aa overlap (1-228:1-224)
10 20 30 40 50 60
pF1KE6 MSMILSASVIRVRDGLPLSASTDYEQSTGMQECRKYFKMLSRKLAQLPDRCTLKTGHYNI
::.:. : :.:::::::::::::. .. . : :. .: :. .::: : : . . ..:
CCDS56 MSVIFFACVVRVRDGLPLSASTDFYHTQDFLEWRRRLKSLALRLAQYPGRGSAEGCDFSI
10 20 30 40 50 60
70 80 90 100 110
pF1KE6 NFISSLG-VSYMMLCTENYPNVLAFSFLDELQKEFITTYNMMKTNTAVRPYCFIEFDNFI
.: ::.: :. : .:. . : ..:: ::. : :: ..:. . : ::: :.:::..:
CCDS56 HF-SSFGDVACMAICSCQCPAAMAFCFLETLWWEFTASYDTTCIGLASRPYAFLEFDSII
70 80 90 100 110
120 130 140 150 160 170
pF1KE6 QRTKQRYNNPRSLSTKINLSDMQTEIKLRPPYQISMCELGSANGVTSAFS-VDCKGAGKI
:..: ..: : . . .: .: :.::.:: ... . :::: .. . . . : ..
CCDS56 QKVKWHFNYVSSSQMECSLEKIQEELKLQPPAVLTLEDTDVANGVMNGHTPMHLEPAPNF
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE6 SSAHQRLEPATLSGIVGFILSLLCGALNLIRGFHAIESLLQSDGDDFNYIIAFFLGTAAC
:.::.: ::...::...:.::::::: : : ::. . : ..
CCDS56 -----RMEPVTALGILSLILNIMCAALNLIRGVHLAEHSLQDPRSWFCWLDQTS
180 190 200 210 220
240 250 260 270 280 290
pF1KE6 LYQCYLLVYYTGWRNVKSFLTFGLICLCNMYLYELRNLWQLFFHVTVGAFVTLQIWLRQA
>>CCDS83523.1 SEC22B gene_id:9554|Hs108|chr1 (215 aa)
initn: 302 init1: 156 opt: 350 Z-score: 449.1 bits: 90.7 E(32554): 1.1e-18
Smith-Waterman score: 350; 40.8% identity (72.8% similar) in 147 aa overlap (3-146:1-143)
10 20 30 40 50
pF1KE6 MSMILSASVIRVRDGLPLSASTDYEQSTG--MQECRKYFKMLSRKLA-QLPDRCTLKTGH
:.: . . :: :::::.:: . ....: .:. .. :.: ::: : : ::::..:
CCDS83 MVLLTMIARVADGLPLAASMQEDEQSGRDLQQYQSQAKQLFRKLNEQSPTRCTLEAGA
10 20 30 40 50
60 70 80 90 100 110
pF1KE6 YNINFISSLGVSYMMLCTENYPNVLAFSFLDELQKEFITTYNMMKTNTAVRPYCFIEFDN
.....: :: :..:: .:. :::..:..:..:: .. :. :. ::: :::::.
CCDS83 MTFHYIIEQGVCYLVLCEAAFPKKLAFAYLEDLHSEFDEQHGK-KVPTVSRPYSFIEFDT
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE6 FIQRTKQRYNNPRSLSTKINLSDMQTEIKLRPPYQISMCELGSANGVTSAFSVDCKGAGK
:::.::. : . :. . ::....::..
CCDS83 FIQKTKKLYIDSRA---RRNLGSINTELQDVQRIMVANIEEVLQRGEALSALDSKANNLS
120 130 140 150 160 170
307 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Nov 8 12:43:45 2016 done: Tue Nov 8 12:43:45 2016
Total Scan time: 2.070 Total Display time: 0.000
Function used was FASTA [36.3.4 Apr, 2011]