Result of FASTA (omim) for
pFN21AE6364
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE6364, 354 aa
1>>>pF1KE6364 354 - 354 aa - 354 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.1158+/-0.000381; mu= 17.3679+/- 0.024
mean_var=66.1103+/-13.477, 0's: 0 Z-trim(111.8): 77 B-trim: 90 in 1/51
Lambda= 0.157739
statistics sampled from 20430 (20511) to 20430 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.625), E-opt: 0.2 (0.24), width: 16
Scan time: 6.730
The best scores are: opt bits E(85289)
XP_016868630 (OMIM: 611292) PREDICTED: clavesin-1 ( 354) 2378 550.2 2.5e-156
NP_775790 (OMIM: 611292) clavesin-1 [Homo sapiens] ( 354) 2378 550.2 2.5e-156
XP_016868631 (OMIM: 611292) PREDICTED: clavesin-1 ( 354) 2378 550.2 2.5e-156
XP_016865755 (OMIM: 616945) PREDICTED: clavesin-2 ( 327) 1789 416.1 5.3e-116
NP_001010852 (OMIM: 616945) clavesin-2 [Homo sapie ( 327) 1789 416.1 5.3e-116
XP_011520172 (OMIM: 136880,180090,607475,607476) P ( 317) 689 165.8 1.2e-40
NP_000317 (OMIM: 136880,180090,607475,607476) reti ( 317) 689 165.8 1.2e-40
XP_016877949 (OMIM: 136880,180090,607475,607476) P ( 326) 689 165.8 1.2e-40
NP_000361 (OMIM: 277460,600415) alpha-tocopherol t ( 278) 481 118.4 1.9e-26
XP_016884276 (OMIM: 612825) PREDICTED: SEC14-like ( 465) 258 67.8 5.4e-11
NP_777635 (OMIM: 612824) SEC14-like protein 3 isof ( 400) 257 67.6 5.6e-11
XP_011528430 (OMIM: 612824) PREDICTED: SEC14-like ( 412) 257 67.6 5.7e-11
NP_001154840 (OMIM: 612825) SEC14-like protein 4 i ( 360) 246 65.0 2.9e-10
NP_777637 (OMIM: 612825) SEC14-like protein 4 isof ( 406) 246 65.1 3.2e-10
NP_002824 (OMIM: 600768) tyrosine-protein phosphat ( 593) 244 64.7 5.9e-10
XP_006716531 (OMIM: 277460,600415) PREDICTED: alph ( 162) 222 59.3 6.7e-09
NP_203740 (OMIM: 607558) SEC14-like protein 2 isof ( 392) 217 58.4 3e-08
NP_036561 (OMIM: 607558) SEC14-like protein 2 isof ( 403) 217 58.5 3.1e-08
NP_001244307 (OMIM: 612824) SEC14-like protein 3 i ( 323) 186 51.3 3.4e-06
NP_001244308 (OMIM: 612824) SEC14-like protein 3 i ( 341) 186 51.4 3.6e-06
NP_001244311 (OMIM: 612824) SEC14-like protein 3 i ( 341) 186 51.4 3.6e-06
XP_016884280 (OMIM: 612825) PREDICTED: SEC14-like ( 352) 184 50.9 5e-06
XP_006724298 (OMIM: 612825) PREDICTED: SEC14-like ( 352) 184 50.9 5e-06
XP_016884278 (OMIM: 612825) PREDICTED: SEC14-like ( 352) 184 50.9 5e-06
XP_011528466 (OMIM: 612825) PREDICTED: SEC14-like ( 391) 183 50.7 6.4e-06
NP_001278861 (OMIM: 607558) SEC14-like protein 2 i ( 349) 156 44.5 0.00041
NP_001191133 (OMIM: 607558) SEC14-like protein 2 i ( 320) 151 43.4 0.00085
NP_001137473 (OMIM: 601504) SEC14-like protein 1 i ( 681) 141 41.3 0.0076
NP_002994 (OMIM: 601504) SEC14-like protein 1 isof ( 715) 141 41.3 0.0079
NP_001191339 (OMIM: 601504) SEC14-like protein 1 i ( 715) 141 41.3 0.0079
NP_001137471 (OMIM: 601504) SEC14-like protein 1 i ( 715) 141 41.3 0.0079
NP_001137470 (OMIM: 601504) SEC14-like protein 1 i ( 715) 141 41.3 0.0079
NP_001034662 (OMIM: 601504) SEC14-like protein 1 i ( 719) 141 41.3 0.0079
NP_001191337 (OMIM: 601504) SEC14-like protein 1 i ( 719) 141 41.3 0.0079
>>XP_016868630 (OMIM: 611292) PREDICTED: clavesin-1 isof (354 aa)
initn: 2378 init1: 2378 opt: 2378 Z-score: 2927.5 bits: 550.2 E(85289): 2.5e-156
Smith-Waterman score: 2378; 100.0% identity (100.0% similar) in 354 aa overlap (1-354:1-354)
10 20 30 40 50 60
pF1KE6 MGPVSLLPKYQKLNTWNGDLAKMTHLQAGLSPETIEKARLELNENPDVLHQDIQQVRDMI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MGPVSLLPKYQKLNTWNGDLAKMTHLQAGLSPETIEKARLELNENPDVLHQDIQQVRDMI
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 ITRPDIGFLRTDDAFILRFLRARKFHQADAFRLLAQYFQYRQLNLDMFKNFKADDPGIKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ITRPDIGFLRTDDAFILRFLRARKFHQADAFRLLAQYFQYRQLNLDMFKNFKADDPGIKR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 ALIDGFPGVLENRDHYGRKILLLFAANWDQSRNSFTDILRAILLSLEVLIEDPELQINGF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ALIDGFPGVLENRDHYGRKILLLFAANWDQSRNSFTDILRAILLSLEVLIEDPELQINGF
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE6 ILIIDWSNFSFKQASKLTPSILKLAIEGLQDSFPARFGGVHFVNQPWYIHALYTLIKPFL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ILIIDWSNFSFKQASKLTPSILKLAIEGLQDSFPARFGGVHFVNQPWYIHALYTLIKPFL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE6 KDKTRKRIFLHGNNLNSLHQLIHPEFLPSEFGGTLPPYDMGTWARTLLGPDYSDENDYTH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KDKTRKRIFLHGNNLNSLHQLIHPEFLPSEFGGTLPPYDMGTWARTLLGPDYSDENDYTH
250 260 270 280 290 300
310 320 330 340 350
pF1KE6 TSYNAMHVKHTSSNLERECSPKLMKRSQSVVEAGTLKHEEKGENENTQPLLALD
::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TSYNAMHVKHTSSNLERECSPKLMKRSQSVVEAGTLKHEEKGENENTQPLLALD
310 320 330 340 350
>>NP_775790 (OMIM: 611292) clavesin-1 [Homo sapiens] (354 aa)
initn: 2378 init1: 2378 opt: 2378 Z-score: 2927.5 bits: 550.2 E(85289): 2.5e-156
Smith-Waterman score: 2378; 100.0% identity (100.0% similar) in 354 aa overlap (1-354:1-354)
10 20 30 40 50 60
pF1KE6 MGPVSLLPKYQKLNTWNGDLAKMTHLQAGLSPETIEKARLELNENPDVLHQDIQQVRDMI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_775 MGPVSLLPKYQKLNTWNGDLAKMTHLQAGLSPETIEKARLELNENPDVLHQDIQQVRDMI
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 ITRPDIGFLRTDDAFILRFLRARKFHQADAFRLLAQYFQYRQLNLDMFKNFKADDPGIKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_775 ITRPDIGFLRTDDAFILRFLRARKFHQADAFRLLAQYFQYRQLNLDMFKNFKADDPGIKR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 ALIDGFPGVLENRDHYGRKILLLFAANWDQSRNSFTDILRAILLSLEVLIEDPELQINGF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_775 ALIDGFPGVLENRDHYGRKILLLFAANWDQSRNSFTDILRAILLSLEVLIEDPELQINGF
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE6 ILIIDWSNFSFKQASKLTPSILKLAIEGLQDSFPARFGGVHFVNQPWYIHALYTLIKPFL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_775 ILIIDWSNFSFKQASKLTPSILKLAIEGLQDSFPARFGGVHFVNQPWYIHALYTLIKPFL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE6 KDKTRKRIFLHGNNLNSLHQLIHPEFLPSEFGGTLPPYDMGTWARTLLGPDYSDENDYTH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_775 KDKTRKRIFLHGNNLNSLHQLIHPEFLPSEFGGTLPPYDMGTWARTLLGPDYSDENDYTH
250 260 270 280 290 300
310 320 330 340 350
pF1KE6 TSYNAMHVKHTSSNLERECSPKLMKRSQSVVEAGTLKHEEKGENENTQPLLALD
::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_775 TSYNAMHVKHTSSNLERECSPKLMKRSQSVVEAGTLKHEEKGENENTQPLLALD
310 320 330 340 350
>>XP_016868631 (OMIM: 611292) PREDICTED: clavesin-1 isof (354 aa)
initn: 2378 init1: 2378 opt: 2378 Z-score: 2927.5 bits: 550.2 E(85289): 2.5e-156
Smith-Waterman score: 2378; 100.0% identity (100.0% similar) in 354 aa overlap (1-354:1-354)
10 20 30 40 50 60
pF1KE6 MGPVSLLPKYQKLNTWNGDLAKMTHLQAGLSPETIEKARLELNENPDVLHQDIQQVRDMI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 MGPVSLLPKYQKLNTWNGDLAKMTHLQAGLSPETIEKARLELNENPDVLHQDIQQVRDMI
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 ITRPDIGFLRTDDAFILRFLRARKFHQADAFRLLAQYFQYRQLNLDMFKNFKADDPGIKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ITRPDIGFLRTDDAFILRFLRARKFHQADAFRLLAQYFQYRQLNLDMFKNFKADDPGIKR
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 ALIDGFPGVLENRDHYGRKILLLFAANWDQSRNSFTDILRAILLSLEVLIEDPELQINGF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ALIDGFPGVLENRDHYGRKILLLFAANWDQSRNSFTDILRAILLSLEVLIEDPELQINGF
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE6 ILIIDWSNFSFKQASKLTPSILKLAIEGLQDSFPARFGGVHFVNQPWYIHALYTLIKPFL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 ILIIDWSNFSFKQASKLTPSILKLAIEGLQDSFPARFGGVHFVNQPWYIHALYTLIKPFL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE6 KDKTRKRIFLHGNNLNSLHQLIHPEFLPSEFGGTLPPYDMGTWARTLLGPDYSDENDYTH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 KDKTRKRIFLHGNNLNSLHQLIHPEFLPSEFGGTLPPYDMGTWARTLLGPDYSDENDYTH
250 260 270 280 290 300
310 320 330 340 350
pF1KE6 TSYNAMHVKHTSSNLERECSPKLMKRSQSVVEAGTLKHEEKGENENTQPLLALD
::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 TSYNAMHVKHTSSNLERECSPKLMKRSQSVVEAGTLKHEEKGENENTQPLLALD
310 320 330 340 350
>>XP_016865755 (OMIM: 616945) PREDICTED: clavesin-2 isof (327 aa)
initn: 1649 init1: 1649 opt: 1789 Z-score: 2203.6 bits: 416.1 E(85289): 5.3e-116
Smith-Waterman score: 1789; 79.8% identity (92.5% similar) in 332 aa overlap (23-354:1-327)
10 20 30 40 50 60
pF1KE6 MGPVSLLPKYQKLNTWNGDLAKMTHLQAGLSPETIEKARLELNENPDVLHQDIQQVRDMI
::::::::::::.::::::::::::.::::::.::::.
XP_016 MTHLQAGLSPETLEKARLELNENPDTLHQDIQEVRDMV
10 20 30
70 80 90 100 110 120
pF1KE6 ITRPDIGFLRTDDAFILRFLRARKFHQADAFRLLAQYFQYRQLNLDMFKNFKADDPGIKR
::::::::::::::::::::::::::. .:::::::::.::: ::::::.::: :::::.
XP_016 ITRPDIGFLRTDDAFILRFLRARKFHHFEAFRLLAQYFEYRQQNLDMFKSFKATDPGIKQ
40 50 60 70 80 90
130 140 150 160 170 180
pF1KE6 ALIDGFPGVLENRDHYGRKILLLFAANWDQSRNSFTDILRAILLSLEVLIEDPELQINGF
:: ::::: : : ::::::::.:::::::::: ...:::::::::::..:::::::.:::
XP_016 ALKDGFPGGLANLDHYGRKILVLFAANWDQSRYTLVDILRAILLSLEAMIEDPELQVNGF
100 110 120 130 140 150
190 200 210 220 230 240
pF1KE6 ILIIDWSNFSFKQASKLTPSILKLAIEGLQDSFPARFGGVHFVNQPWYIHALYTLIKPFL
.::::::::.::::::::::.:.::::::::::::::::.::::::::::::::.:.:::
XP_016 VLIIDWSNFTFKQASKLTPSMLRLAIEGLQDSFPARFGGIHFVNQPWYIHALYTVIRPFL
160 170 180 190 200 210
250 260 270 280 290 300
pF1KE6 KDKTRKRIFLHGNNLNSLHQLIHPEFLPSEFGGTLPPYDMGTWARTLLGPDYSDENDYTH
:.:::::::::::::::::::::::.::::::: :::::::::::::: .:.:...:.
XP_016 KEKTRKRIFLHGNNLNSLHQLIHPEILPSEFGGMLPPYDMGTWARTLLDHEYDDDSEYNV
220 230 240 250 260 270
310 320 330 340 350
pF1KE6 TSYNAMHVKHTSSNLERECSPKLMKRSQSVVEAGTLKHEEKGENENTQPLLALD
::. : ::. .:.: ::: ::::::::. .::. .:.:.:: ::::.::
XP_016 DSYS-MPVKE----VEKELSPKSMKRSQSVVDPTVLKRMDKNEEENMQPLLSLD
280 290 300 310 320
>>NP_001010852 (OMIM: 616945) clavesin-2 [Homo sapiens] (327 aa)
initn: 1649 init1: 1649 opt: 1789 Z-score: 2203.6 bits: 416.1 E(85289): 5.3e-116
Smith-Waterman score: 1789; 79.8% identity (92.5% similar) in 332 aa overlap (23-354:1-327)
10 20 30 40 50 60
pF1KE6 MGPVSLLPKYQKLNTWNGDLAKMTHLQAGLSPETIEKARLELNENPDVLHQDIQQVRDMI
::::::::::::.::::::::::::.::::::.::::.
NP_001 MTHLQAGLSPETLEKARLELNENPDTLHQDIQEVRDMV
10 20 30
70 80 90 100 110 120
pF1KE6 ITRPDIGFLRTDDAFILRFLRARKFHQADAFRLLAQYFQYRQLNLDMFKNFKADDPGIKR
::::::::::::::::::::::::::. .:::::::::.::: ::::::.::: :::::.
NP_001 ITRPDIGFLRTDDAFILRFLRARKFHHFEAFRLLAQYFEYRQQNLDMFKSFKATDPGIKQ
40 50 60 70 80 90
130 140 150 160 170 180
pF1KE6 ALIDGFPGVLENRDHYGRKILLLFAANWDQSRNSFTDILRAILLSLEVLIEDPELQINGF
:: ::::: : : ::::::::.:::::::::: ...:::::::::::..:::::::.:::
NP_001 ALKDGFPGGLANLDHYGRKILVLFAANWDQSRYTLVDILRAILLSLEAMIEDPELQVNGF
100 110 120 130 140 150
190 200 210 220 230 240
pF1KE6 ILIIDWSNFSFKQASKLTPSILKLAIEGLQDSFPARFGGVHFVNQPWYIHALYTLIKPFL
.::::::::.::::::::::.:.::::::::::::::::.::::::::::::::.:.:::
NP_001 VLIIDWSNFTFKQASKLTPSMLRLAIEGLQDSFPARFGGIHFVNQPWYIHALYTVIRPFL
160 170 180 190 200 210
250 260 270 280 290 300
pF1KE6 KDKTRKRIFLHGNNLNSLHQLIHPEFLPSEFGGTLPPYDMGTWARTLLGPDYSDENDYTH
:.:::::::::::::::::::::::.::::::: :::::::::::::: .:.:...:.
NP_001 KEKTRKRIFLHGNNLNSLHQLIHPEILPSEFGGMLPPYDMGTWARTLLDHEYDDDSEYNV
220 230 240 250 260 270
310 320 330 340 350
pF1KE6 TSYNAMHVKHTSSNLERECSPKLMKRSQSVVEAGTLKHEEKGENENTQPLLALD
::. : ::. .:.: ::: ::::::::. .::. .:.:.:: ::::.::
NP_001 DSYS-MPVKE----VEKELSPKSMKRSQSVVDPTVLKRMDKNEEENMQPLLSLD
280 290 300 310 320
>>XP_011520172 (OMIM: 136880,180090,607475,607476) PREDI (317 aa)
initn: 704 init1: 569 opt: 689 Z-score: 850.9 bits: 165.8 E(85289): 1.2e-40
Smith-Waterman score: 689; 39.2% identity (71.6% similar) in 278 aa overlap (30-296:40-314)
10 20 30 40 50
pF1KE6 MGPVSLLPKYQKLNTWNGDLAKMTHLQAGLSPETIEKARLELNENPDVLHQDIQQVRDM
: .:..::. :::: .. .. ......:
XP_011 MVPEEEQELRAQLEQLTTKDHGPVFGPCSQLPRHTLQKAKDELNEREETREEAVRELQEM
10 20 30 40 50 60
60 70 80 90 100
pF1KE6 IITRPDIG----------FLRTDDAFILRFLRARKFHQADAFRLLAQYFQYRQLNLDMFK
. .. : . :..:.:::.:::::. . :..:: : ..: ..:
XP_011 VQAQAASGEELAVAVAERVQEKDSGFFLRFIRARKFNVGRAYELLRGYVNFRLQYPELFD
70 80 90 100 110 120
110 120 130 140 150 160
pF1KE6 NFKADDPGIKRALID-GFPGVLENRDHYGRKILLLFAANWDQSRNSFTDILRAILLSLEV
... : : :. :.:::: .::.::: ..:. ::.... .: .::.: . ::
XP_011 SLS---PEAVRCTIEAGYPGVLSSRDKYGRVVMLFNIENWQSQEITFDEILQAYCFILEK
130 140 150 160 170 180
170 180 190 200 210 220
pF1KE6 LIEDPELQINGFILIIDWSNFSFKQASKLTPSILKLAIEGLQDSFPARFGGVHFVNQPWY
:.:. : ::::: .: ....:...::..: : :. .. ::::::::: ..::..::::
XP_011 LLENEETQINGFCIIENFKGFTMQQAASLRTSDLRKMVDMLQDSFPARFKAIHFIHQPWY
190 200 210 220 230 240
230 240 250 260 270 280
pF1KE6 IHALYTLIKPFLKDKTRKRIFLHGNNLNSLHQLIHPEFLPSEFGGTLPPYDMGTWARTLL
. . :...:::::.: .:.:.::..:....: : ..:::.:::::: :: . :. :.
XP_011 FTTTYNVVKPFLKSKLLERVFVHGDDLSGFYQEIDENILPSDFGGTLPKYDGKAVAEQLF
250 260 270 280 290 300
290 300 310 320 330 340
pF1KE6 GPDYSDENDYTHTSYNAMHVKHTSSNLERECSPKLMKRSQSVVEAGTLKHEEKGENENTQ
::. . ::
XP_011 GPQAQAENTAF
310
>>NP_000317 (OMIM: 136880,180090,607475,607476) retinald (317 aa)
initn: 704 init1: 569 opt: 689 Z-score: 850.9 bits: 165.8 E(85289): 1.2e-40
Smith-Waterman score: 689; 39.2% identity (71.6% similar) in 278 aa overlap (30-296:40-314)
10 20 30 40 50
pF1KE6 MGPVSLLPKYQKLNTWNGDLAKMTHLQAGLSPETIEKARLELNENPDVLHQDIQQVRDM
: .:..::. :::: .. .. ......:
NP_000 MVPEEEQELRAQLEQLTTKDHGPVFGPCSQLPRHTLQKAKDELNEREETREEAVRELQEM
10 20 30 40 50 60
60 70 80 90 100
pF1KE6 IITRPDIG----------FLRTDDAFILRFLRARKFHQADAFRLLAQYFQYRQLNLDMFK
. .. : . :..:.:::.:::::. . :..:: : ..: ..:
NP_000 VQAQAASGEELAVAVAERVQEKDSGFFLRFIRARKFNVGRAYELLRGYVNFRLQYPELFD
70 80 90 100 110 120
110 120 130 140 150 160
pF1KE6 NFKADDPGIKRALID-GFPGVLENRDHYGRKILLLFAANWDQSRNSFTDILRAILLSLEV
... : : :. :.:::: .::.::: ..:. ::.... .: .::.: . ::
NP_000 SLS---PEAVRCTIEAGYPGVLSSRDKYGRVVMLFNIENWQSQEITFDEILQAYCFILEK
130 140 150 160 170 180
170 180 190 200 210 220
pF1KE6 LIEDPELQINGFILIIDWSNFSFKQASKLTPSILKLAIEGLQDSFPARFGGVHFVNQPWY
:.:. : ::::: .: ....:...::..: : :. .. ::::::::: ..::..::::
NP_000 LLENEETQINGFCIIENFKGFTMQQAASLRTSDLRKMVDMLQDSFPARFKAIHFIHQPWY
190 200 210 220 230 240
230 240 250 260 270 280
pF1KE6 IHALYTLIKPFLKDKTRKRIFLHGNNLNSLHQLIHPEFLPSEFGGTLPPYDMGTWARTLL
. . :...:::::.: .:.:.::..:....: : ..:::.:::::: :: . :. :.
NP_000 FTTTYNVVKPFLKSKLLERVFVHGDDLSGFYQEIDENILPSDFGGTLPKYDGKAVAEQLF
250 260 270 280 290 300
290 300 310 320 330 340
pF1KE6 GPDYSDENDYTHTSYNAMHVKHTSSNLERECSPKLMKRSQSVVEAGTLKHEEKGENENTQ
::. . ::
NP_000 GPQAQAENTAF
310
>>XP_016877949 (OMIM: 136880,180090,607475,607476) PREDI (326 aa)
initn: 704 init1: 569 opt: 689 Z-score: 850.7 bits: 165.8 E(85289): 1.2e-40
Smith-Waterman score: 689; 39.2% identity (71.6% similar) in 278 aa overlap (30-296:49-323)
10 20 30 40 50
pF1KE6 MGPVSLLPKYQKLNTWNGDLAKMTHLQAGLSPETIEKARLELNENPDVLHQDIQQVRDM
: .:..::. :::: .. .. ......:
XP_016 MVPEEEQELRAQLEQLTTKDHGPVFGPCSQLPRHTLQKAKDELNEREETREEAVRELQEM
20 30 40 50 60 70
60 70 80 90 100
pF1KE6 IITRPDIG----------FLRTDDAFILRFLRARKFHQADAFRLLAQYFQYRQLNLDMFK
. .. : . :..:.:::.:::::. . :..:: : ..: ..:
XP_016 VQAQAASGEELAVAVAERVQEKDSGFFLRFIRARKFNVGRAYELLRGYVNFRLQYPELFD
80 90 100 110 120 130
110 120 130 140 150 160
pF1KE6 NFKADDPGIKRALID-GFPGVLENRDHYGRKILLLFAANWDQSRNSFTDILRAILLSLEV
... : : :. :.:::: .::.::: ..:. ::.... .: .::.: . ::
XP_016 SLS---PEAVRCTIEAGYPGVLSSRDKYGRVVMLFNIENWQSQEITFDEILQAYCFILEK
140 150 160 170 180 190
170 180 190 200 210 220
pF1KE6 LIEDPELQINGFILIIDWSNFSFKQASKLTPSILKLAIEGLQDSFPARFGGVHFVNQPWY
:.:. : ::::: .: ....:...::..: : :. .. ::::::::: ..::..::::
XP_016 LLENEETQINGFCIIENFKGFTMQQAASLRTSDLRKMVDMLQDSFPARFKAIHFIHQPWY
200 210 220 230 240 250
230 240 250 260 270 280
pF1KE6 IHALYTLIKPFLKDKTRKRIFLHGNNLNSLHQLIHPEFLPSEFGGTLPPYDMGTWARTLL
. . :...:::::.: .:.:.::..:....: : ..:::.:::::: :: . :. :.
XP_016 FTTTYNVVKPFLKSKLLERVFVHGDDLSGFYQEIDENILPSDFGGTLPKYDGKAVAEQLF
260 270 280 290 300 310
290 300 310 320 330 340
pF1KE6 GPDYSDENDYTHTSYNAMHVKHTSSNLERECSPKLMKRSQSVVEAGTLKHEEKGENENTQ
::. . ::
XP_016 GPQAQAENTAF
320
>>NP_000361 (OMIM: 277460,600415) alpha-tocopherol trans (278 aa)
initn: 491 init1: 399 opt: 481 Z-score: 595.9 bits: 118.4 E(85289): 1.9e-26
Smith-Waterman score: 481; 38.4% identity (69.0% similar) in 203 aa overlap (73-273:49-247)
50 60 70 80 90 100
pF1KE6 NENPDVLHQDIQQVRDMIITRPDIGFLRTDDAFILRFLRARKFHQADAFRLLAQYFQYRQ
:.:.::::::: : :.::: .:...:
NP_000 DHSPLLQPGLAALRRRAREAGVPLAPLPLTDSFLLRFLRARDFDLDLAWRLLKNYYKWRA
20 30 40 50 60 70
110 120 130 140 150 160
pF1KE6 LNLDMFKNFKADDP-GIKRALIDGFPGVLENRDHYGRKILLLFAANWDQSRNSFTDILRA
.. ... . :. .: :. :::..:: : :.:. :.:: . . :..:.
NP_000 ECPEISADLHPRSIIGLLKA---GYHGVLRSRDPTGSKVLIYRIAHWDPKVFTAYDVFRV
80 90 100 110 120 130
170 180 190 200 210 220
pF1KE6 ILLSLEVLIEDPELQINGFILIIDWSNFSFKQASKLTPSILKLAIEGLQDSFPARFGGVH
:.. :..... : : ::. :.: ...:..: ..:::. : : :::: . :.:
NP_000 SLITSELIVQEVETQRNGIKAIFDLEGWQFSHAFQITPSVAKKIAAVLTDSFPLKVRGIH
140 150 160 170 180 190
230 240 250 260 270 280
pF1KE6 FVNQPWYIHALYTLIKPFLKDKTRKRIFLHGNNLN-SLHQLIHPEFLPSEFGGTLPPYDM
..:.: .::....::::: .: ..:: .:::: . :: : . :..:: :.::
NP_000 LINEPVIFHAVFSMIKPFLTEKIKERIHMHGNNYKQSLLQHF-PDILPLEYGGEEFSMED
200 210 220 230 240 250
290 300 310 320 330 340
pF1KE6 GTWARTLLGPDYSDENDYTHTSYNAMHVKHTSSNLERECSPKLMKRSQSVVEAGTLKHEE
NP_000 ICQEWTNFIMKSEDYLSSISESIQ
260 270
>>XP_016884276 (OMIM: 612825) PREDICTED: SEC14-like prot (465 aa)
initn: 157 init1: 87 opt: 258 Z-score: 318.4 bits: 67.8 E(85289): 5.4e-11
Smith-Waterman score: 261; 24.3% identity (55.6% similar) in 313 aa overlap (16-313:52-342)
10 20 30 40
pF1KE6 MGPVSLLPKYQKLNTWNGDLAKMTHLQAGLSPETIEKARLELNEN
:.: : .. .. .: ::... .. ::
XP_016 WAGGCPIFRWQSRSGQHPAWSSGGVDWWMMWEGLGAGLVAPEVMRAPPTIRSSSAQFREN
30 40 50 60 70 80
50 60 70 80 90 100
pF1KE6 PDVLHQDIQQVRDMIITRPDIGFLRTDDAFILRFLRARKFHQADAFRLLAQYFQYR-QLN
..:.. :. .:: :.::.::::.: . .: .....: : .
XP_016 ----------LQDLLPILPN-----ADDYFLLRWLRARNFDLQKSEDMLRRHMEFRKQQD
90 100 110 120
110 120 130 140 150 160
pF1KE6 LDMFKNFKADDPGIKRALIDGFPGVLENRDHYGRKILLLFAANWDQS----RNSFTDILR
:: . ... : . . : :. : : . :. : . . . .. : . : :..:
XP_016 LDNIVTWQP--PEVIQ-LYDS--GGLCGYDYEGCPVYFNIIGSLDPKGLLLSASKQDMIR
130 140 150 160 170 180
170 180 190 200 210
pF1KE6 AILLSLEVLIEDPELQ-------INGFILIIDWSNFSFKQASKLTPSILKLAIEGLQDSF
. :.:... ::: :. ....: ..:.:. : . . . . :. ..
XP_016 KRIKVCELLLHECELQTQKLGRKIEMALMVFDMEGLSLKHLWKPAVEVYQQFFSILEANY
190 200 210 220 230 240
220 230 240 250 260 270
pF1KE6 PARFGGVHFVNQPWYIHALYTLIKPFLKDKTRKRIFLHGNNLNS-LHQLIHPEFLPSEFG
: . .. . : . . ..:.: :....::..: . :.: .. : ..: :. :: :::
XP_016 PETLKNLIVIRAPKLFPVAFNLVKSFMSEETRRKIVILGDNWKQELTKFISPDQLPVEFG
250 260 270 280 290 300
280 290 300 310 320 330
pF1KE6 GTLPPYDMGTWARTLLGPDYSDE--NDYTHTSYNAMHVKHTSSNLERECSPKLMKRSQSV
::. : :. . : .:. : ..: .. .:: :
XP_016 GTMTDPD-GN-PKCLTKINYGGEVPKSYYLCEQVRLQYEHTRSVGRGSSLQVENEILFPG
310 320 330 340 350
340 350
pF1KE6 VEAGTLKHEEKGENENTQPLLALD
XP_016 CVLRWQFASDGGDIGFGVFLKTKMGEQQSAREMTEVLPSQRYNAHMVPEDGSLTCLQAGV
360 370 380 390 400 410
354 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Nov 8 12:29:37 2016 done: Tue Nov 8 12:29:38 2016
Total Scan time: 6.730 Total Display time: 0.020
Function used was FASTA [36.3.4 Apr, 2011]