Result of FASTA (ccds) for
pFN21AE6361
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE6361, 348 aa
1>>>pF1KE6361 348 - 348 aa - 348 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.3783+/-0.000776; mu= 16.0858+/- 0.047
mean_var=68.5296+/-13.289, 0's: 0 Z-trim(109.1): 179 B-trim: 0 in 0/49
Lambda= 0.154930
statistics sampled from 10449 (10628) to 10449 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.707), E-opt: 0.2 (0.326), width: 16
Scan time: 1.960
The best scores are: opt bits E(32554)
CCDS44881.1 TMPRSS12 gene_id:283471|Hs108|chr12 ( 348) 2399 544.9 3.6e-155
CCDS13571.1 TMPRSS15 gene_id:5651|Hs108|chr21 (1019) 663 157.2 5.7e-38
CCDS14101.1 ACR gene_id:49|Hs108|chr22 ( 421) 640 151.8 9.6e-37
CCDS33564.1 TMPRSS2 gene_id:7113|Hs108|chr21 ( 492) 623 148.0 1.5e-35
CCDS54486.1 TMPRSS2 gene_id:7113|Hs108|chr21 ( 529) 623 148.1 1.6e-35
CCDS32993.1 HPN gene_id:3249|Hs108|chr19 ( 417) 619 147.1 2.5e-35
CCDS34120.1 KLKB1 gene_id:3818|Hs108|chr4 ( 638) 617 146.8 4.8e-35
CCDS74856.1 TMPRSS6 gene_id:164656|Hs108|chr22 ( 802) 614 146.1 9.2e-35
CCDS13941.1 TMPRSS6 gene_id:164656|Hs108|chr22 ( 811) 614 146.1 9.3e-35
CCDS58790.1 TMPRSS3 gene_id:64699|Hs108|chr21 ( 453) 608 144.7 1.5e-34
CCDS12088.1 TMPRSS9 gene_id:360200|Hs108|chr19 (1059) 605 144.2 4.7e-34
CCDS8487.1 ST14 gene_id:6768|Hs108|chr11 ( 855) 603 143.7 5.3e-34
CCDS13686.1 TMPRSS3 gene_id:64699|Hs108|chr21 ( 454) 598 142.4 6.8e-34
CCDS55788.1 TMPRSS13 gene_id:84000|Hs108|chr11 ( 532) 585 139.6 5.9e-33
CCDS41721.1 TMPRSS13 gene_id:84000|Hs108|chr11 ( 567) 585 139.6 6.2e-33
CCDS76482.1 TMPRSS4 gene_id:56649|Hs108|chr11 ( 290) 579 138.1 8.9e-33
CCDS58185.1 TMPRSS13 gene_id:84000|Hs108|chr11 ( 563) 582 138.9 9.8e-33
CCDS53717.1 TMPRSS4 gene_id:56649|Hs108|chr11 ( 397) 579 138.2 1.2e-32
CCDS44743.1 TMPRSS4 gene_id:56649|Hs108|chr11 ( 432) 579 138.2 1.2e-32
CCDS53716.1 TMPRSS4 gene_id:56649|Hs108|chr11 ( 435) 579 138.2 1.3e-32
CCDS31684.1 TMPRSS4 gene_id:56649|Hs108|chr11 ( 437) 579 138.2 1.3e-32
CCDS10476.1 PRSS27 gene_id:83886|Hs108|chr16 ( 290) 573 136.7 2.3e-32
CCDS43129.2 TMPRSS7 gene_id:344805|Hs108|chr3 ( 717) 573 137.0 4.8e-32
CCDS75122.1 CORIN gene_id:10699|Hs108|chr4 ( 938) 573 137.0 6e-32
CCDS3477.1 CORIN gene_id:10699|Hs108|chr4 (1042) 573 137.0 6.6e-32
CCDS73391.1 TMPRSS5 gene_id:80975|Hs108|chr11 ( 413) 567 135.5 7.7e-32
CCDS73392.1 TMPRSS5 gene_id:80975|Hs108|chr11 ( 448) 567 135.5 8.3e-32
CCDS44735.1 TMPRSS5 gene_id:80975|Hs108|chr11 ( 457) 567 135.5 8.4e-32
CCDS45469.1 PRSS8 gene_id:5652|Hs108|chr16 ( 343) 565 135.0 9e-32
CCDS3520.1 TMPRSS11F gene_id:389208|Hs108|chr4 ( 438) 562 134.4 1.8e-31
CCDS10481.1 PRSS22 gene_id:64063|Hs108|chr16 ( 317) 560 133.8 1.8e-31
CCDS8812.1 CELA1 gene_id:1990|Hs108|chr12 ( 258) 551 131.8 6.2e-31
CCDS3847.1 F11 gene_id:2160|Hs108|chr4 ( 625) 550 131.8 1.5e-30
CCDS157.1 CELA2A gene_id:63036|Hs108|chr1 ( 269) 544 130.2 1.9e-30
CCDS46816.1 PRSS42 gene_id:339906|Hs108|chr3 ( 293) 541 129.6 3.3e-30
CCDS34302.1 F12 gene_id:2161|Hs108|chr5 ( 615) 535 128.4 1.5e-29
CCDS1563.1 PRSS38 gene_id:339501|Hs108|chr1 ( 326) 531 127.4 1.7e-29
CCDS30605.1 CELA2B gene_id:51032|Hs108|chr1 ( 269) 525 126.0 3.6e-29
CCDS74669.1 PRSS56 gene_id:646960|Hs108|chr2 ( 603) 521 125.3 1.3e-28
CCDS3518.1 TMPRSS11D gene_id:9407|Hs108|chr4 ( 418) 517 124.3 1.8e-28
CCDS5279.1 PLG gene_id:5340|Hs108|chr6 ( 810) 520 125.1 2e-28
CCDS34049.1 CFI gene_id:3426|Hs108|chr4 ( 583) 517 124.4 2.4e-28
CCDS42110.1 PRSS33 gene_id:260429|Hs108|chr16 ( 280) 513 123.3 2.4e-28
CCDS82945.1 CFI gene_id:3426|Hs108|chr4 ( 576) 512 123.3 5.1e-28
CCDS82946.1 CFI gene_id:3426|Hs108|chr4 ( 591) 512 123.3 5.2e-28
CCDS3709.1 PRSS12 gene_id:8492|Hs108|chr4 ( 875) 513 123.6 6.2e-28
CCDS5976.1 PRSS55 gene_id:203074|Hs108|chr8 ( 352) 508 122.3 6.3e-28
CCDS156.1 CTRC gene_id:11330|Hs108|chr1 ( 268) 505 121.5 8e-28
CCDS53579.1 HABP2 gene_id:3026|Hs108|chr10 ( 534) 505 121.7 1.4e-27
CCDS7577.1 HABP2 gene_id:3026|Hs108|chr10 ( 560) 505 121.7 1.5e-27
>>CCDS44881.1 TMPRSS12 gene_id:283471|Hs108|chr12 (348 aa)
initn: 2399 init1: 2399 opt: 2399 Z-score: 2899.2 bits: 544.9 E(32554): 3.6e-155
Smith-Waterman score: 2399; 99.7% identity (100.0% similar) in 348 aa overlap (1-348:1-348)
10 20 30 40 50 60
pF1KE6 MRLGLLSVALLFVGSSHLYSDHYSPSGRHRLGPSPEPAASSQQAEAVRKRLRRRREGGAH
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 MRLGLLSVALLFVGSSHLYSDHYSPSGRHRLGPSPEPAASSQQAEAVRKRLRRRREGGAH
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 AKDCGTAPLKDVLQGSRIIGGTEAQAGAWPWVVSLQIKYGRVLVHVCGGTLVRERWVLTA
:.::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 AEDCGTAPLKDVLQGSRIIGGTEAQAGAWPWVVSLQIKYGRVLVHVCGGTLVRERWVLTA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 AHCTKDASDPLMWTAVIGTNNIHGRYPHTKKIKIKAIIIHPNFILESYVNDIALFHLKKA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 AHCTKDASDPLMWTAVIGTNNIHGRYPHTKKIKIKAIIIHPNFILESYVNDIALFHLKKA
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE6 VRYNDYIQPICLPFDVFQILDGNTKCFISGWGRTKEEGNATNILQDAEVHYISREMCNSE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 VRYNDYIQPICLPFDVFQILDGNTKCFISGWGRTKEEGNATNILQDAEVHYISREMCNSE
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE6 RSYGGIIPNTSFCAGDEDGAFDTCRGDSGGPLMCYLPEYKRFFVMGITSYGHGCGRRGFP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 RSYGGIIPNTSFCAGDEDGAFDTCRGDSGGPLMCYLPEYKRFFVMGITSYGHGCGRRGFP
250 260 270 280 290 300
310 320 330 340
pF1KE6 GVYIGPSFYQKWLTEHFFHASTQGILTINILRGQILIALCFVILLATT
::::::::::::::::::::::::::::::::::::::::::::::::
CCDS44 GVYIGPSFYQKWLTEHFFHASTQGILTINILRGQILIALCFVILLATT
310 320 330 340
>>CCDS13571.1 TMPRSS15 gene_id:5651|Hs108|chr21 (1019 aa)
initn: 559 init1: 137 opt: 663 Z-score: 795.2 bits: 157.2 E(32554): 5.7e-38
Smith-Waterman score: 663; 40.6% identity (67.0% similar) in 261 aa overlap (62-319:770-1019)
40 50 60 70 80 90
pF1KE6 GPSPEPAASSQQAEAVRKRLRRRREGGAHAKDCGTA-PLKDVLQGSRIIGGTEAQAGAWP
:.:: .:. .:.::..:. ::::
CCDS13 KLNTAPDGHLILTPSQQCLQDSLIRLQCNHKSCGKKLAAQDIT--PKIVGGSNAKEGAWP
740 750 760 770 780 790
100 110 120 130 140
pF1KE6 WVVSLQIKYGRVLVHVCGGTLVRERWVLTAAHCTKDAS-DPLMWTAVIGTNNIHG-RYPH
:::.: ::.: ::..:: :...::::. . .: :::..: . . :.
CCDS13 WVVGLYYG-GRLL---CGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLHMKSNLTSPQ
800 810 820 830 840 850
150 160 170 180 190 200
pF1KE6 TKKIKIKAIIIHPNFILESYVNDIALFHLKKAVRYNDYIQPICLPFDVFQILDGNTKCFI
: : :.:.:.. . ::::..::. : :.::::::::: . :.. . .: :
CCDS13 TVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLPEEN-QVFPPGRNCSI
860 870 880 890 900 910
210 220 230 240 250 260
pF1KE6 SGWGRTKEEGNATNILQDAEVHYISREMCNSERSYGGIIPNTSFCAGDEDGAFDTCRGDS
.::: . .:...::::.:.: .: : :... .: : .::: :.:..:.:.:::
CCDS13 AGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITENM-ICAGYEEGGIDSCQGDS
920 930 940 950 960 970
270 280 290 300 310 320
pF1KE6 GGPLMCYLPEYKRFFVMGITSYGHGCGRRGFPGVYIGPSFYQKWLTEHFFHASTQGILTI
:::::: : .:.:. :.::.:. :. . :::: : . .:. . :.:
CCDS13 GGPLMC--QENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWI-QSFLH
980 990 1000 1010
330 340
pF1KE6 NILRGQILIALCFVILLATT
>>CCDS14101.1 ACR gene_id:49|Hs108|chr22 (421 aa)
initn: 607 init1: 269 opt: 640 Z-score: 773.1 bits: 151.8 E(32554): 9.6e-37
Smith-Waterman score: 640; 39.4% identity (62.5% similar) in 259 aa overlap (64-313:29-285)
40 50 60 70 80 90
pF1KE6 SPEPAASSQQAEAVRKRLRRRREGGAHAKDCGTAPLKDVLQGSRIIGGTEAQAGAWPWVV
:: .. : ::.:: :: :::::.:
CCDS14 MVEMLPTAILLVLAVSVVAKDNATCDGPCGLRFRQNPQGGVRIVGGKAAQHGAWPWMV
10 20 30 40 50
100 110 120 130 140 150
pF1KE6 SLQI-KYGRVLVHVCGGTLVRERWVLTAAHCTKDASDPLMWTAVIGTNNIHGRYPHTKKI
:::: :. :.:::.:. ::::::::: .. : :.:...: : ..: .
CCDS14 SLQIFTYNSHRYHTCGGSLLNSRWVLTAAHCFVGKNNVHDWRLVFGAKEI--TYGNNKPV
60 70 80 90 100 110
160 170 180 190 200
pF1KE6 K-------IKAIIIHPNFILESYVNDIALFHLKKAVRYNDYIQPICLPFDVFQILDGNTK
: .. :::: .. . ::::: .. . . .: : ::: . :. .
CCDS14 KAPLQERYVEKIIIHEKYNSATEGNDIALVEITPPISCGRFIGPGCLPHFKAGLPRGSQS
120 130 140 150 160 170
210 220 230 240 250 260
pF1KE6 CFISGWGRTKEEG-NATNILQDAEVHYISREMCNSERSYGGIIPNTSFCAGDEDGAFDTC
:...::: .:.. ..::..:.: :. ..::: . :.: . :. ::: : .:::
CCDS14 CWVAGWGYIEEKAPRPSSILMEARVDLIDLDLCNSTQWYNGRVQPTNVCAGYPVGKIDTC
180 190 200 210 220 230
270 280 290 300 310 320
pF1KE6 RGDSGGPLMCYLPEYKRFFVMGITSYGHGCGRRGFPGVYIGPSFYQKWLTEHFFHASTQG
.::::::::: . . . :.::::.: ::.: ::.: . : .:.
CCDS14 QGDSGGPLMCKDSKESAYVVVGITSWGVGCARAKRPGIYTATWPYLNWIASKIGSNALRM
240 250 260 270 280 290
330 340
pF1KE6 ILTINILRGQILIALCFVILLATT
CCDS14 IQSATPPPPTTRPPPIRPPFSHPISAHLPWYFQPPPRPLPPRPPAAQPRPPPSPPPPPPP
300 310 320 330 340 350
>>CCDS33564.1 TMPRSS2 gene_id:7113|Hs108|chr21 (492 aa)
initn: 570 init1: 217 opt: 623 Z-score: 751.6 bits: 148.0 E(32554): 1.5e-35
Smith-Waterman score: 623; 38.2% identity (66.9% similar) in 251 aa overlap (64-313:244-484)
40 50 60 70 80 90
pF1KE6 SPEPAASSQQAEAVRKRLRRRREGGAHAKDCGTAPLKDVLQGSRIIGGTEAQAGAWPWVV
::. :.. : :::.:: : ::::: :
CCDS33 TSAGNVDIYKKLYHSDACSSKAVVSLRCIACGVN-LNSSRQ-SRIVGGESALPGAWPWQV
220 230 240 250 260 270
100 110 120 130 140 150
pF1KE6 SLQIKYGRVLVHVCGGTLVRERWVLTAAHCT-KDASDPLMWTAVIGTNNIHGRYPHTKKI
::... ::::::... .:..:::::. : ..: ::: : .. . .
CCDS33 SLHVQN----VHVCGGSIITPEWIVTAAHCVEKPLNNPWHWTAFAGILR-QSFMFYGAGY
280 290 300 310 320
160 170 180 190 200 210
pF1KE6 KIKAIIIHPNFILESYVNDIALFHLKKAVRYNDYIQPICLPFDVFQILDGNTKCFISGWG
... .: :::. .. :::::..:.: . .:: ..:.::: . ..:. . :.:::::
CCDS33 QVEKVISHPNYDSKTKNNDIALMKLQKPLTFNDLVKPVCLP-NPGMMLQPEQLCWISGWG
330 340 350 360 370 380
220 230 240 250 260 270
pF1KE6 RTKEEGNATNILQDAEVHYISREMCNSERSYGGIIPNTSFCAGDEDGAFDTCRGDSGGPL
:.:.:.....:. :.: : . :::. : ..: . .::: .: :.:.:::::::
CCDS33 ATEEKGKTSEVLNAAKVLLIETQRCNSRYVYDNLITPAMICAGFLQGNVDSCQGDSGGPL
390 400 410 420 430 440
280 290 300 310 320 330
pF1KE6 MCYLPEYKRFFVMGITSYGHGCGRRGFPGVYIGPSFYQKWLTEHFFHASTQGILTINILR
. . . ....: ::.: ::.. :::: . . :.
CCDS33 V--TSKNNIWWLIGDTSWGSGCAKAYRPGVYGNVMVFTDWIYRQMRADG
450 460 470 480 490
340
pF1KE6 GQILIALCFVILLATT
>>CCDS54486.1 TMPRSS2 gene_id:7113|Hs108|chr21 (529 aa)
initn: 570 init1: 217 opt: 623 Z-score: 751.1 bits: 148.1 E(32554): 1.6e-35
Smith-Waterman score: 623; 38.2% identity (66.9% similar) in 251 aa overlap (64-313:281-521)
40 50 60 70 80 90
pF1KE6 SPEPAASSQQAEAVRKRLRRRREGGAHAKDCGTAPLKDVLQGSRIIGGTEAQAGAWPWVV
::. :.. : :::.:: : ::::: :
CCDS54 TSAGNVDIYKKLYHSDACSSKAVVSLRCIACGVN-LNSSRQ-SRIVGGESALPGAWPWQV
260 270 280 290 300
100 110 120 130 140 150
pF1KE6 SLQIKYGRVLVHVCGGTLVRERWVLTAAHCT-KDASDPLMWTAVIGTNNIHGRYPHTKKI
::... ::::::... .:..:::::. : ..: ::: : .. . .
CCDS54 SLHVQN----VHVCGGSIITPEWIVTAAHCVEKPLNNPWHWTAFAGILR-QSFMFYGAGY
310 320 330 340 350 360
160 170 180 190 200 210
pF1KE6 KIKAIIIHPNFILESYVNDIALFHLKKAVRYNDYIQPICLPFDVFQILDGNTKCFISGWG
... .: :::. .. :::::..:.: . .:: ..:.::: . ..:. . :.:::::
CCDS54 QVEKVISHPNYDSKTKNNDIALMKLQKPLTFNDLVKPVCLP-NPGMMLQPEQLCWISGWG
370 380 390 400 410 420
220 230 240 250 260 270
pF1KE6 RTKEEGNATNILQDAEVHYISREMCNSERSYGGIIPNTSFCAGDEDGAFDTCRGDSGGPL
:.:.:.....:. :.: : . :::. : ..: . .::: .: :.:.:::::::
CCDS54 ATEEKGKTSEVLNAAKVLLIETQRCNSRYVYDNLITPAMICAGFLQGNVDSCQGDSGGPL
430 440 450 460 470 480
280 290 300 310 320 330
pF1KE6 MCYLPEYKRFFVMGITSYGHGCGRRGFPGVYIGPSFYQKWLTEHFFHASTQGILTINILR
. . . ....: ::.: ::.. :::: . . :.
CCDS54 V--TSKNNIWWLIGDTSWGSGCAKAYRPGVYGNVMVFTDWIYRQMRADG
490 500 510 520
340
pF1KE6 GQILIALCFVILLATT
>>CCDS32993.1 HPN gene_id:3249|Hs108|chr19 (417 aa)
initn: 489 init1: 246 opt: 619 Z-score: 747.8 bits: 147.1 E(32554): 2.5e-35
Smith-Waterman score: 619; 36.1% identity (62.1% similar) in 285 aa overlap (53-327:142-415)
30 40 50 60 70 80
pF1KE6 YSPSGRHRLGPSPEPAASSQQAEAVRKRLRRRREGGAHAKDCGTAPLKDVLQGSRIIGGT
: : .: .::: . : .::.::
CCDS32 NGTSGFFCVDEGRLPHTQRLLEVISVCDCPRGRFLAAICQDCG----RRKLPVDRIVGGR
120 130 140 150 160
90 100 110 120 130 140
pF1KE6 EAQAGAWPWVVSLQIKYGRVLVHVCGGTLVRERWVLTAAHCTKDASDPLM-WTAVIGTNN
... : ::: :::. : .:.:::.:. :::::::: . . : : . :.
CCDS32 DTSLGRWPWQVSLRYD-G---AHLCGGSLLSGDWVLTAAHCFPERNRVLSRWRVFAGA--
170 180 190 200 210 220
150 160 170 180 190
pF1KE6 IHGRYPHTKKIKIKAIIIHPNFI------LESYVNDIALFHLKKAVRYNDYIQPICLPFD
. :: .. ..:.. : ... : ::::: ::.. . ..::::.:::
CCDS32 VAQASPHGLQLGVQAVVYHGGYLPFRDPNSEENSNDIALVHLSSPLPLTEYIQPVCLPAA
230 240 250 260 270 280
200 210 220 230 240 250
pF1KE6 VFQILDGNTKCFISGWGRTKEEGNATNILQDAEVHYISREMCNSERSYGGIIPNTSFCAG
..::. : ..::: :. :. ...::.:.: :: ..::. ::. : ::::
CCDS32 GQALVDGKI-CTVTGWGNTQYYGQQAGVLQEARVPIISNDVCNGADFYGNQIKPKMFCAG
290 300 310 320 330 340
260 270 280 290 300 310
pF1KE6 DEDGAFDTCRGDSGGPLMCY--LPEYKRFFVMGITSYGHGCGRRGFPGVYIGPSFYQKWL
.:..:.:.::::::..: . . :. . ::.:.: ::. :::: : ...:.
CCDS32 YPEGGIDACQGDSGGPFVCEDSISRTPRWRLCGIVSWGTGCALAQKPGVYTKVSDFREWI
350 360 370 380 390 400
320 330 340
pF1KE6 TEHF-FHASTQGILTINILRGQILIALCFVILLATT
. . :. ..:..:
CCDS32 FQAIKTHSEASGMVTQL
410
>>CCDS34120.1 KLKB1 gene_id:3818|Hs108|chr4 (638 aa)
initn: 593 init1: 227 opt: 617 Z-score: 742.7 bits: 146.8 E(32554): 4.8e-35
Smith-Waterman score: 617; 40.5% identity (64.0% similar) in 242 aa overlap (76-315:389-623)
50 60 70 80 90 100
pF1KE6 AVRKRLRRRREGGAHAKDCGTAPLKDVLQGSRIIGGTEAQAGAWPWVVSLQIKYGRVLVH
.::.:::... : ::: ::::.: . :
CCDS34 RIAYGTQGSSGYSLRLCNTGDNSVCTTKTSTRIVGGTNSSWGEWPWQVSLQVKL-TAQRH
360 370 380 390 400 410
110 120 130 140 150 160
pF1KE6 VCGGTLVRERWVLTAAHCTKDASDPLMWTAVIGTNNIHGRYPHTKKIKIKAIIIHPNFIL
.:::.:. ..:::::::: .: : :. : .:: :::: :. .
CCDS34 LCGGSLIGHQWVLTAAHCFDGLPLQDVWRIYSGILNLSDITKDTPFSQIKEIIIHQNYKV
420 430 440 450 460 470
170 180 190 200 210 220
pF1KE6 ESYVNDIALFHLKKAVRYNDYIQPICLPF--DVFQILDGNTKCFISGWGRTKEEGNATNI
.::::..:. . :... .::::: :. : :.:...::: .::.:. ::
CCDS34 SEGNHDIALIKLQAPLNYTEFQKPICLPSKGDTSTIY---TNCWVTGWGFSKEKGEIQNI
480 490 500 510 520 530
230 240 250 260 270 280
pF1KE6 LQDAEVHYISREMCNSERSYGGIIPNTSFCAGDEDGAFDTCRGDSGGPLMCYLPEYKRFF
:: ... .. : :. .: : . ::: ..:. :.:.:::::::.: . :
CCDS34 LQKVNIPLVTNEECQ-KRYQDYKITQRMVCAGYKEGGKDACKGDSGGPLVCKHNGMWR--
540 550 560 570 580 590
290 300 310 320 330 340
pF1KE6 VMGITSYGHGCGRRGFPGVYIGPSFYQKWLTEHFFHASTQGILTINILRGQILIALCFVI
..::::.:.::.:: :::: . :. :. :
CCDS34 LVGITSWGEGCARREQPGVYTKVAEYMDWILEKTQSSDGKAQMQSPA
600 610 620 630
pF1KE6 LLATT
>>CCDS74856.1 TMPRSS6 gene_id:164656|Hs108|chr22 (802 aa)
initn: 585 init1: 135 opt: 614 Z-score: 737.6 bits: 146.1 E(32554): 9.2e-35
Smith-Waterman score: 614; 36.1% identity (65.0% similar) in 266 aa overlap (55-315:549-799)
30 40 50 60 70 80
pF1KE6 PSGRHRLGPSPEPAASSQQAEAVRKRLRRRREGGAHAK-DCGTAPLKDVLQG--SRIIGG
:.:. . . ::: ::: :::.::
CCDS74 GVPCGTFTFQCEDRSCVKKPNPQCDGRPDCRDGSDEEHCDCG-------LQGPSSRIVGG
520 530 540 550 560 570
90 100 110 120 130
pF1KE6 TEAQAGAWPWVVSLQIKYGRVLVHVCGGTLVRERWVLTAAHCTKDAS--DPLMWTAVIGT
. .. : ::: .:::.. :: :.:::.:. .:::.::::: .. : . ..::. .:
CCDS74 AVSSEGEWPWQASLQVR-GR---HICGGALIADRWVITAAHCFQEDSMASTVLWTVFLGK
580 590 600 610 620
140 150 160 170 180 190
pF1KE6 NNIHGRYPHTKKIKIKAIIIHPNFILESYVNDIALFHLKKAVRYNDYIQPICLPFDVFQI
..:.: ..:.. ...:: .:. :.::..: . : . ..:.::: ..
CCDS74 VWQNSRWPGEVSFKVSRLLLHPYHEEDSHDYDVALLQLDHPVVRSAAVRPVCLPARS-HF
630 640 650 660 670 680
200 210 220 230 240 250
pF1KE6 LDGNTKCFISGWGRTKEEGNATNILQDAEVHYISREMCNSERSYGGIIPNTSFCAGDEDG
.. . .:.:.::: .: : .: :: ..:. : ...:. : . : .::: . :
CCDS74 FEPGLHCWITGWGALREGGPISNALQKVDVQLIPQDLCSEVYRYQ-VTPRM-LCAGYRKG
690 700 710 720 730 740
260 270 280 290 300 310
pF1KE6 AFDTCRGDSGGPLMCYLPEYKRFFVMGITSYGHGCGRRGFPGVYIGPSFYQKWLTEHFFH
:.:.:::::::.: :.:. :..:.: :::: .. ::: . .:. .
CCDS74 KKDACQGDSGGPLVCK-ALSGRWFLAGLVSWGLGCGRPNYFGVYTRITGVISWIQQVVT
750 760 770 780 790 800
320 330 340
pF1KE6 ASTQGILTINILRGQILIALCFVILLATT
>>CCDS13941.1 TMPRSS6 gene_id:164656|Hs108|chr22 (811 aa)
initn: 585 init1: 135 opt: 614 Z-score: 737.5 bits: 146.1 E(32554): 9.3e-35
Smith-Waterman score: 614; 36.1% identity (65.0% similar) in 266 aa overlap (55-315:558-808)
30 40 50 60 70 80
pF1KE6 PSGRHRLGPSPEPAASSQQAEAVRKRLRRRREGGAHAK-DCGTAPLKDVLQG--SRIIGG
:.:. . . ::: ::: :::.::
CCDS13 GVPCGTFTFQCEDRSCVKKPNPQCDGRPDCRDGSDEEHCDCG-------LQGPSSRIVGG
530 540 550 560 570 580
90 100 110 120 130
pF1KE6 TEAQAGAWPWVVSLQIKYGRVLVHVCGGTLVRERWVLTAAHCTKDAS--DPLMWTAVIGT
. .. : ::: .:::.. :: :.:::.:. .:::.::::: .. : . ..::. .:
CCDS13 AVSSEGEWPWQASLQVR-GR---HICGGALIADRWVITAAHCFQEDSMASTVLWTVFLGK
590 600 610 620 630
140 150 160 170 180 190
pF1KE6 NNIHGRYPHTKKIKIKAIIIHPNFILESYVNDIALFHLKKAVRYNDYIQPICLPFDVFQI
..:.: ..:.. ...:: .:. :.::..: . : . ..:.::: ..
CCDS13 VWQNSRWPGEVSFKVSRLLLHPYHEEDSHDYDVALLQLDHPVVRSAAVRPVCLPARS-HF
640 650 660 670 680 690
200 210 220 230 240 250
pF1KE6 LDGNTKCFISGWGRTKEEGNATNILQDAEVHYISREMCNSERSYGGIIPNTSFCAGDEDG
.. . .:.:.::: .: : .: :: ..:. : ...:. : . : .::: . :
CCDS13 FEPGLHCWITGWGALREGGPISNALQKVDVQLIPQDLCSEVYRYQ-VTPRM-LCAGYRKG
700 710 720 730 740 750
260 270 280 290 300 310
pF1KE6 AFDTCRGDSGGPLMCYLPEYKRFFVMGITSYGHGCGRRGFPGVYIGPSFYQKWLTEHFFH
:.:.:::::::.: :.:. :..:.: :::: .. ::: . .:. .
CCDS13 KKDACQGDSGGPLVCK-ALSGRWFLAGLVSWGLGCGRPNYFGVYTRITGVISWIQQVVT
760 770 780 790 800 810
320 330 340
pF1KE6 ASTQGILTINILRGQILIALCFVILLATT
>>CCDS58790.1 TMPRSS3 gene_id:64699|Hs108|chr21 (453 aa)
initn: 567 init1: 243 opt: 608 Z-score: 734.0 bits: 144.7 E(32554): 1.5e-34
Smith-Waterman score: 608; 38.2% identity (65.6% similar) in 241 aa overlap (76-316:215-446)
50 60 70 80 90 100
pF1KE6 AVRKRLRRRREGGAHAKDCGTAPLKDVLQGSRIIGGTEAQAGAWPWVVSLQIKYGRVLVH
:::.::. . . ::: .:::.. : :
CCDS58 HHSVYVREGCASGHVVTLQCTACGHRRGYSSRIVGGNMSLLSQWPWQASLQFQ-GY---H
190 200 210 220 230 240
110 120 130 140 150 160
pF1KE6 VCGGTLVRERWVLTAAHCTKDASDPLMWTAVIGTNNIHGRYPHTKKIKIKAIIIHPNFIL
.:::... :..:::::. : : :: .: .. : ... .. :. : ..
CCDS58 LCGGSVITPLWIITAAHCVYDLYLPKSWTIQVGLVSLLDN-PAPSHL-VEKIVYHSKYKP
250 260 270 280 290
170 180 190 200 210 220
pF1KE6 ESYVNDIALFHLKKAVRYNDYIQPICLPFDVFQILDGNTKCFISGWGRTKEEGNATNILQ
. :::::..: . .:..:::.::: . .. ::.. :. :::: :.. :.:. .:.
CCDS58 KRLGNDIALMKLAGPLTFNEMIQPVCLPNSEENFPDGKV-CWTSGWGATEDGGDASPVLN
300 310 320 330 340 350
230 240 250 260 270 280
pF1KE6 DAEVHYISREMCNSERSYGGIIPNTSFCAGDEDGAFDTCRGDSGGPLMCYLPEYKRFFVM
: : :: ..:: . ::::: . .::: :. :.:.:::::::.: : . . ..
CCDS58 HAAVPLISNKICNHRDVYGGIISPSMLCAGYLTGGVDSCQGDSGGPLVCQ--ERRLWKLV
360 370 380 390 400 410
290 300 310 320 330 340
pF1KE6 GITSYGHGCGRRGFPGVYIGPSFYQKWLTEHFFHASTQGILTINILRGQILIALCFVILL
: ::.: ::.. . :::: . . :. :.
CCDS58 GATSFGIGCAEVNKPGVYTRVTSFLDWIHEQMERDLKT
420 430 440 450
pF1KE6 ATT
348 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Nov 8 12:27:55 2016 done: Tue Nov 8 12:27:56 2016
Total Scan time: 1.960 Total Display time: 0.030
Function used was FASTA [36.3.4 Apr, 2011]