Result of FASTA (omim) for
pFN21AE6356
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE6356, 321 aa
1>>>pF1KE6356 321 - 321 aa - 321 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.3051+/-0.000287; mu= 17.0590+/- 0.018
mean_var=84.6410+/-16.613, 0's: 0 Z-trim(120.9): 310 B-trim: 13 in 2/54
Lambda= 0.139407
statistics sampled from 36355 (36675) to 36355 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.781), E-opt: 0.2 (0.43), width: 16
Scan time: 7.680
The best scores are: opt bits E(85289)
NP_036599 (OMIM: 609341) tryptase gamma preproprot ( 321) 2284 468.5 8.3e-132
XP_011520748 (OMIM: 609341) PREDICTED: tryptase ga ( 346) 2132 437.9 1.4e-122
XP_011520749 (OMIM: 609341) PREDICTED: tryptase ga ( 346) 2132 437.9 1.4e-122
NP_077078 (OMIM: 191081) tryptase beta-2 prepropro ( 275) 825 175.0 1.6e-43
NP_003285 (OMIM: 191080) tryptase alpha/beta-1 pre ( 275) 817 173.4 4.9e-43
XP_005255530 (OMIM: 609343) PREDICTED: brain-speci ( 317) 778 165.6 1.2e-40
NP_071402 (OMIM: 609343) brain-specific serine pro ( 317) 778 165.6 1.2e-40
NP_001231924 (OMIM: 610050) transmembrane protease ( 563) 717 153.5 9.4e-37
NP_001193718 (OMIM: 610050) transmembrane protease ( 532) 704 150.9 5.5e-36
NP_001070731 (OMIM: 610050) transmembrane protease ( 567) 704 150.9 5.8e-36
NP_001275930 (OMIM: 206200,609862) transmembrane p ( 802) 699 150.0 1.5e-35
NP_705837 (OMIM: 206200,609862) transmembrane prot ( 811) 699 150.0 1.5e-35
NP_001305325 (OMIM: 229000,612423) plasma kallikre ( 436) 687 147.4 5.1e-35
XP_016863673 (OMIM: 229000,612423) PREDICTED: plas ( 436) 687 147.4 5.1e-35
NP_000883 (OMIM: 229000,612423) plasma kallikrein ( 638) 687 147.5 6.7e-35
XP_011530232 (OMIM: 229000,612423) PREDICTED: plas ( 649) 687 147.5 6.8e-35
XP_016863670 (OMIM: 229000,612423) PREDICTED: plas ( 649) 687 147.5 6.8e-35
NP_000292 (OMIM: 173350,217090) plasminogen isofor ( 810) 672 144.6 6.5e-34
NP_001182058 (OMIM: 613517,613858) serine protease ( 603) 669 143.9 7.9e-34
NP_001277025 (OMIM: 606565) transmembrane protease ( 290) 654 140.6 3.7e-33
NP_001167023 (OMIM: 606565) transmembrane protease ( 397) 654 140.7 4.7e-33
NP_001277023 (OMIM: 606565) transmembrane protease ( 412) 654 140.7 4.8e-33
NP_001077416 (OMIM: 606565) transmembrane protease ( 432) 654 140.8 5e-33
NP_001167022 (OMIM: 606565) transmembrane protease ( 435) 654 140.8 5e-33
NP_063947 (OMIM: 606565) transmembrane protease se ( 437) 654 140.8 5.1e-33
XP_005271672 (OMIM: 606565) PREDICTED: transmembra ( 454) 653 140.6 6e-33
XP_011541204 (OMIM: 606565) PREDICTED: transmembra ( 456) 653 140.6 6e-33
XP_011541203 (OMIM: 606565) PREDICTED: transmembra ( 489) 653 140.6 6.3e-33
XP_005271671 (OMIM: 606565) PREDICTED: transmembra ( 492) 653 140.6 6.3e-33
XP_005271670 (OMIM: 606565) PREDICTED: transmembra ( 494) 653 140.6 6.4e-33
NP_001275679 (OMIM: 606751) transmembrane protease ( 413) 651 140.1 7.4e-33
NP_001275680 (OMIM: 606751) transmembrane protease ( 448) 651 140.2 7.8e-33
NP_110397 (OMIM: 606751) transmembrane protease se ( 457) 651 140.2 7.9e-33
NP_115780 (OMIM: 605511) transmembrane protease se ( 327) 647 139.2 1.1e-32
NP_076927 (OMIM: 605511) transmembrane protease se ( 454) 647 139.4 1.4e-32
NP_001243246 (OMIM: 605511) transmembrane protease ( 453) 646 139.2 1.6e-32
XP_005265767 (OMIM: 605369) PREDICTED: transmembra ( 301) 642 138.2 2e-32
NP_004253 (OMIM: 605369) transmembrane protease se ( 418) 642 138.3 2.6e-32
XP_011528035 (OMIM: 602060) PREDICTED: transmembra ( 384) 639 137.7 3.7e-32
XP_005261100 (OMIM: 602060) PREDICTED: transmembra ( 452) 639 137.8 4.2e-32
XP_011528033 (OMIM: 602060) PREDICTED: transmembra ( 492) 639 137.8 4.5e-32
NP_005647 (OMIM: 602060) transmembrane protease se ( 492) 639 137.8 4.5e-32
XP_016864340 (OMIM: 605369) PREDICTED: transmembra ( 234) 635 136.7 4.5e-32
NP_001128571 (OMIM: 602060) transmembrane protease ( 529) 639 137.8 4.7e-32
XP_011526284 (OMIM: 610477) PREDICTED: transmembra ( 562) 637 137.4 6.5e-32
XP_011526282 (OMIM: 610477) PREDICTED: transmembra ( 690) 637 137.5 7.6e-32
NP_892018 (OMIM: 610477) transmembrane protease se (1059) 637 137.7 1e-31
XP_011526280 (OMIM: 610477) PREDICTED: transmembra (1093) 637 137.7 1.1e-31
NP_036349 (OMIM: 609272) tryptase delta precursor ( 242) 622 134.1 2.8e-31
NP_001107859 (OMIM: 611704) transmembrane protease ( 418) 617 133.3 8.5e-31
>>NP_036599 (OMIM: 609341) tryptase gamma preproprotein (321 aa)
initn: 2284 init1: 2284 opt: 2284 Z-score: 2487.4 bits: 468.5 E(85289): 8.3e-132
Smith-Waterman score: 2284; 100.0% identity (100.0% similar) in 321 aa overlap (1-321:1-321)
10 20 30 40 50 60
pF1KE6 MALGACGLLLLLAVPGVSLRTLQPGCGRPQVSDAGGRIVGGHAAPAGAWPWQASLRLRRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 MALGACGLLLLLAVPGVSLRTLQPGCGRPQVSDAGGRIVGGHAAPAGAWPWQASLRLRRV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 HVCGGSLLSPQWVLTAAHCFSGSLNSSDYQVHLGELEITLSPHFSTVRQIILHSSPSGQP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 HVCGGSLLSPQWVLTAAHCFSGSLNSSDYQVHLGELEITLSPHFSTVRQIILHSSPSGQP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 GTSGDIALVELSVPVTLSSRILPVCLPEASDDFCPGIRCWVTGWGYTREGEPLPPPYSLR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 GTSGDIALVELSVPVTLSSRILPVCLPEASDDFCPGIRCWVTGWGYTREGEPLPPPYSLR
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE6 EVKVSVVDTETCRRDYPGPGGSILQPDMLCARGPGDACQDDSGGPLVCQVNGAWVQAGIV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 EVKVSVVDTETCRRDYPGPGGSILQPDMLCARGPGDACQDDSGGPLVCQVNGAWVQAGIV
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE6 SWGEGCGRPNRPGVYTRVPAYVNWIRRHITASGGSESGYPRLPLLAGFFLPGLFLLLVSC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_036 SWGEGCGRPNRPGVYTRVPAYVNWIRRHITASGGSESGYPRLPLLAGFFLPGLFLLLVSC
250 260 270 280 290 300
310 320
pF1KE6 VLLAKCLLHPSADGTPFPAPD
:::::::::::::::::::::
NP_036 VLLAKCLLHPSADGTPFPAPD
310 320
>>XP_011520748 (OMIM: 609341) PREDICTED: tryptase gamma (346 aa)
initn: 2125 init1: 2125 opt: 2132 Z-score: 2321.7 bits: 437.9 E(85289): 1.4e-122
Smith-Waterman score: 2132; 94.3% identity (97.2% similar) in 318 aa overlap (4-321:30-346)
10 20 30
pF1KE6 MALGACGLLLLLAVPGVSLRTLQPGCGRPQVSDA
:. .. .: . ::. ... ::::::::::
XP_011 MLLGRVWQTRELKSKVPKKAGRCGQGRLHGGSAVGFLGSPPGTP-SSFDLGCGRPQVSDA
10 20 30 40 50
40 50 60 70 80 90
pF1KE6 GGRIVGGHAAPAGAWPWQASLRLRRVHVCGGSLLSPQWVLTAAHCFSGSLNSSDYQVHLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GGRIVGGHAAPAGAWPWQASLRLRRVHVCGGSLLSPQWVLTAAHCFSGSLNSSDYQVHLG
60 70 80 90 100 110
100 110 120 130 140 150
pF1KE6 ELEITLSPHFSTVRQIILHSSPSGQPGTSGDIALVELSVPVTLSSRILPVCLPEASDDFC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ELEITLSPHFSTVRQIILHSSPSGQPGTSGDIALVELSVPVTLSSRILPVCLPEASDDFC
120 130 140 150 160 170
160 170 180 190 200 210
pF1KE6 PGIRCWVTGWGYTREGEPLPPPYSLREVKVSVVDTETCRRDYPGPGGSILQPDMLCARGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PGIRCWVTGWGYTREGEPLPPPYSLREVKVSVVDTETCRRDYPGPGGSILQPDMLCARGP
180 190 200 210 220 230
220 230 240 250 260 270
pF1KE6 GDACQDDSGGPLVCQVNGAWVQAGIVSWGEGCGRPNRPGVYTRVPAYVNWIRRHITASGG
:::::::::::::::::::::::: :::::::::::::::::::::::::::::::::::
XP_011 GDACQDDSGGPLVCQVNGAWVQAGTVSWGEGCGRPNRPGVYTRVPAYVNWIRRHITASGG
240 250 260 270 280 290
280 290 300 310 320
pF1KE6 SESGYPRLPLLAGFFLPGLFLLLVSCVLLAKCLLHPSADGTPFPAPD
:::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SESGYPRLPLLAGFFLPGLFLLLVSCVLLAKCLLHPSADGTPFPAPD
300 310 320 330 340
>>XP_011520749 (OMIM: 609341) PREDICTED: tryptase gamma (346 aa)
initn: 2125 init1: 2125 opt: 2132 Z-score: 2321.7 bits: 437.9 E(85289): 1.4e-122
Smith-Waterman score: 2132; 94.3% identity (97.2% similar) in 318 aa overlap (4-321:30-346)
10 20 30
pF1KE6 MALGACGLLLLLAVPGVSLRTLQPGCGRPQVSDA
:. .. .: . ::. ... ::::::::::
XP_011 MLLGRVWQTRELKSKVPKKAGRCGQGRLHGGSAVGFLGSPPGTP-SSFDLGCGRPQVSDA
10 20 30 40 50
40 50 60 70 80 90
pF1KE6 GGRIVGGHAAPAGAWPWQASLRLRRVHVCGGSLLSPQWVLTAAHCFSGSLNSSDYQVHLG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 GGRIVGGHAAPAGAWPWQASLRLRRVHVCGGSLLSPQWVLTAAHCFSGSLNSSDYQVHLG
60 70 80 90 100 110
100 110 120 130 140 150
pF1KE6 ELEITLSPHFSTVRQIILHSSPSGQPGTSGDIALVELSVPVTLSSRILPVCLPEASDDFC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 ELEITLSPHFSTVRQIILHSSPSGQPGTSGDIALVELSVPVTLSSRILPVCLPEASDDFC
120 130 140 150 160 170
160 170 180 190 200 210
pF1KE6 PGIRCWVTGWGYTREGEPLPPPYSLREVKVSVVDTETCRRDYPGPGGSILQPDMLCARGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PGIRCWVTGWGYTREGEPLPPPYSLREVKVSVVDTETCRRDYPGPGGSILQPDMLCARGP
180 190 200 210 220 230
220 230 240 250 260 270
pF1KE6 GDACQDDSGGPLVCQVNGAWVQAGIVSWGEGCGRPNRPGVYTRVPAYVNWIRRHITASGG
:::::::::::::::::::::::: :::::::::::::::::::::::::::::::::::
XP_011 GDACQDDSGGPLVCQVNGAWVQAGTVSWGEGCGRPNRPGVYTRVPAYVNWIRRHITASGG
240 250 260 270 280 290
280 290 300 310 320
pF1KE6 SESGYPRLPLLAGFFLPGLFLLLVSCVLLAKCLLHPSADGTPFPAPD
:::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SESGYPRLPLLAGFFLPGLFLLLVSCVLLAKCLLHPSADGTPFPAPD
300 310 320 330 340
>>NP_077078 (OMIM: 191081) tryptase beta-2 preproprotein (275 aa)
initn: 732 init1: 311 opt: 825 Z-score: 902.4 bits: 175.0 E(85289): 1.6e-43
Smith-Waterman score: 825; 47.3% identity (72.2% similar) in 273 aa overlap (9-269:4-271)
10 20 30 40 50
pF1KE6 MALGACGLLLLLAVPGVSLRTLQ-PGCGRPQVSDAGGRIVGGHAAPAGAWPWQASLRLRR
:::::.: .. :. :. :. .. .: ::::. :: . ::::.:::.:
NP_077 MLNLLLLALPVLASRAYAAPAPGQA-LQRVG--IVGGQEAPRSKWPWQVSLRVRD
10 20 30 40 50
60 70 80 90 100 110
pF1KE6 ---VHVCGGSLLSPQWVLTAAHCFSGSLNS-SDYQVHLGELEITLSPHFSTVRQIILHSS
.: :::::. :::::::::: . .... . .:.: : .. . .. : .::.: .
NP_077 RYWMHFCGGSLIHPQWVLTAAHCVGPDVKDLAALRVQLREQHLYYQDQLLPVSRIIVHPQ
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE6 -PSGQPGTSGDIALVELSVPVTLSSRILPVCLPEASDDFCPGIRCWVTGWGYTREGEPLP
..: : .::::.:: ::..::.. : :: ::. : ::. ::::::: . . : ::
NP_077 FYTAQIG--ADIALLELEEPVNVSSHVHTVTLPPASETFPPGMPCWVTGWGDVDNDERLP
120 130 140 150 160 170
180 190 200 210 220
pF1KE6 PPYSLREVKVSVVDTETCRRDY-----PGPGGSILQPDMLCARGPG-DACQDDSGGPLVC
::. :..::: ..... : : : :.. ::::: . :.:: ::::::::
NP_077 PPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRIVRDDMLCAGNTRRDSCQGDSGGPLVC
180 190 200 210 220 230
230 240 250 260 270 280
pF1KE6 QVNGAWVQAGIVSWGEGCGRPNRPGVYTRVPAYVNWIRRHITASGGSESGYPRLPLLAGF
.:::.:.:::.:::::::..:::::.:::: :..::....
NP_077 KVNGTWLQAGVVSWGEGCAQPNRPGIYTRVTYYLDWIHHYVPKKP
240 250 260 270
290 300 310 320
pF1KE6 FLPGLFLLLVSCVLLAKCLLHPSADGTPFPAPD
>>NP_003285 (OMIM: 191080) tryptase alpha/beta-1 precurs (275 aa)
initn: 725 init1: 311 opt: 817 Z-score: 893.7 bits: 173.4 E(85289): 4.9e-43
Smith-Waterman score: 817; 46.9% identity (72.2% similar) in 273 aa overlap (9-269:4-271)
10 20 30 40 50
pF1KE6 MALGACGLLLLLAVPGVSLRTLQ-PGCGRPQVSDAGGRIVGGHAAPAGAWPWQASLRLRR
:::::.: .. :. :. :. .. .: ::::. :: . ::::.:::..
NP_003 MLNLLLLALPVLASRAYAAPAPGQA-LQRVG--IVGGQEAPRSKWPWQVSLRVHG
10 20 30 40 50
60 70 80 90 100 110
pF1KE6 ---VHVCGGSLLSPQWVLTAAHCFSGSLNS-SDYQVHLGELEITLSPHFSTVRQIILHSS
.: :::::. :::::::::: . .... . .:.: : .. . .. : .::.: .
NP_003 PYWMHFCGGSLIHPQWVLTAAHCVGPDVKDLAALRVQLREQHLYYQDQLLPVSRIIVHPQ
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE6 -PSGQPGTSGDIALVELSVPVTLSSRILPVCLPEASDDFCPGIRCWVTGWGYTREGEPLP
..: : .::::.:: ::..::.. : :: ::. : ::. ::::::: . . : ::
NP_003 FYTAQIG--ADIALLELEEPVNVSSHVHTVTLPPASETFPPGMPCWVTGWGDVDNDERLP
120 130 140 150 160 170
180 190 200 210 220
pF1KE6 PPYSLREVKVSVVDTETCRRDY-----PGPGGSILQPDMLCARGPG-DACQDDSGGPLVC
::. :..::: ..... : : : :.. ::::: . :.:: ::::::::
NP_003 PPFPLKQVKVPIMENHICDAKYHLGAYTGDDVRIVRDDMLCAGNTRRDSCQGDSGGPLVC
180 190 200 210 220 230
230 240 250 260 270 280
pF1KE6 QVNGAWVQAGIVSWGEGCGRPNRPGVYTRVPAYVNWIRRHITASGGSESGYPRLPLLAGF
.:::.:.:::.:::::::..:::::.:::: :..::....
NP_003 KVNGTWLQAGVVSWGEGCAQPNRPGIYTRVTYYLDWIHHYVPKKP
240 250 260 270
290 300 310 320
pF1KE6 FLPGLFLLLVSCVLLAKCLLHPSADGTPFPAPD
>>XP_005255530 (OMIM: 609343) PREDICTED: brain-specific (317 aa)
initn: 717 init1: 266 opt: 778 Z-score: 850.5 bits: 165.6 E(85289): 1.2e-40
Smith-Waterman score: 778; 42.6% identity (67.9% similar) in 277 aa overlap (3-267:15-287)
10 20 30 40
pF1KE6 MALGACGLLLLLAVPGV--SLRT-LQPGCGRPQVSDAGGRIVGGHAAP
::. ::::: .. . : . :.::.:: . :.:::. .
XP_005 MVVSGAPPALGGGCLGTFTSLLLLASTAILNAARIPVPPACGKPQQLN---RVVGGEDST
10 20 30 40 50
50 60 70 80 90 100
pF1KE6 AGAWPWQASLRLRRVHVCGGSLLSPQWVLTAAHCFSGSLNSSD-YQVHLGELEITLSPHF
. ::: .:.. .: :.::::. .::.::::::. .::. ..: :: .. .:
XP_005 DSEWPWIVSIQKNGTHHCAGSLLTSRWVITAAHCFKDNLNKPYLFSVLLGAWQLG-NPGS
60 70 80 90 100 110
110 120 130 140 150 160
pF1KE6 ST----VRQIILHSSPSGQPGTSGDIALVELSVPVTLSSRILPVCLPEASDDFCPGIRCW
. : . : : . :. .:::::.: . .: :.::.:::.:: . :. .::
XP_005 RSQKVGVAWVEPHPVYSWKEGACADIALVRLERSIQFSERVLPICLPDASIHLPPNTHCW
120 130 140 150 160 170
170 180 190 200 210
pF1KE6 VTGWGYTREGEPLPPPYSLREVKVSVVDTETCRRDY-PGPGGSILQPDMLCA---RGPGD
..::: ..: ::: : .:...:: ..:.:.: . : : : . . ::::: .: :
XP_005 ISGWGSIQDGVPLPHPQTLQKLKVPIIDSEVCSHLYWRGAGQGPITEDMLCAGYLEGERD
180 190 200 210 220 230
220 230 240 250 260 270
pF1KE6 ACQDDSGGPLVCQVNGAWVQAGIVSWGEGCGRPNRPGVYTRVPAYVNWIRRHITASGGSE
:: ::::::.:::.:::. :::.::::::.. :::::: . :. .:...
XP_005 ACLGDSGGPLMCQVDGAWLLAGIISWGEGCAERNRPGVYISLSAHRSWVEKIVQGVQLRG
240 250 260 270 280 290
280 290 300 310 320
pF1KE6 SGYPRLPLLAGFFLPGLFLLLVSCVLLAKCLLHPSADGTPFPAPD
XP_005 RAQGGGALRAPSQGSGAAARS
300 310
>>NP_071402 (OMIM: 609343) brain-specific serine proteas (317 aa)
initn: 717 init1: 266 opt: 778 Z-score: 850.5 bits: 165.6 E(85289): 1.2e-40
Smith-Waterman score: 778; 42.6% identity (67.9% similar) in 277 aa overlap (3-267:15-287)
10 20 30 40
pF1KE6 MALGACGLLLLLAVPGV--SLRT-LQPGCGRPQVSDAGGRIVGGHAAP
::. ::::: .. . : . :.::.:: . :.:::. .
NP_071 MVVSGAPPALGGGCLGTFTSLLLLASTAILNAARIPVPPACGKPQQLN---RVVGGEDST
10 20 30 40 50
50 60 70 80 90 100
pF1KE6 AGAWPWQASLRLRRVHVCGGSLLSPQWVLTAAHCFSGSLNSSD-YQVHLGELEITLSPHF
. ::: .:.. .: :.::::. .::.::::::. .::. ..: :: .. .:
NP_071 DSEWPWIVSIQKNGTHHCAGSLLTSRWVITAAHCFKDNLNKPYLFSVLLGAWQLG-NPGS
60 70 80 90 100 110
110 120 130 140 150 160
pF1KE6 ST----VRQIILHSSPSGQPGTSGDIALVELSVPVTLSSRILPVCLPEASDDFCPGIRCW
. : . : : . :. .:::::.: . .: :.::.:::.:: . :. .::
NP_071 RSQKVGVAWVEPHPVYSWKEGACADIALVRLERSIQFSERVLPICLPDASIHLPPNTHCW
120 130 140 150 160 170
170 180 190 200 210
pF1KE6 VTGWGYTREGEPLPPPYSLREVKVSVVDTETCRRDY-PGPGGSILQPDMLCA---RGPGD
..::: ..: ::: : .:...:: ..:.:.: . : : : . . ::::: .: :
NP_071 ISGWGSIQDGVPLPHPQTLQKLKVPIIDSEVCSHLYWRGAGQGPITEDMLCAGYLEGERD
180 190 200 210 220 230
220 230 240 250 260 270
pF1KE6 ACQDDSGGPLVCQVNGAWVQAGIVSWGEGCGRPNRPGVYTRVPAYVNWIRRHITASGGSE
:: ::::::.:::.:::. :::.::::::.. :::::: . :. .:...
NP_071 ACLGDSGGPLMCQVDGAWLLAGIISWGEGCAERNRPGVYISLSAHRSWVEKIVQGVQLRG
240 250 260 270 280 290
280 290 300 310 320
pF1KE6 SGYPRLPLLAGFFLPGLFLLLVSCVLLAKCLLHPSADGTPFPAPD
NP_071 RAQGGGALRAPSQGSGAAARS
300 310
>>NP_001231924 (OMIM: 610050) transmembrane protease ser (563 aa)
initn: 575 init1: 368 opt: 717 Z-score: 780.9 bits: 153.5 E(85289): 9.4e-37
Smith-Waterman score: 717; 42.4% identity (66.8% similar) in 262 aa overlap (18-274:306-563)
10 20 30 40
pF1KE6 MALGACGLLLLLAVPGVSLRTLQPGCGRPQVSDAGGRIVGGHAAPAG
: : .. :.. . :::::: : .
NP_001 EVAHRDFANSFSILRYNSTIQESLHRSECPSQRYISLQCSHCGLRAMTGRIVGGALASDS
280 290 300 310 320 330
50 60 70 80 90 100
pF1KE6 AWPWQASLRLRRVHVCGGSLLSPQWVLTAAHCFSGSLNS--SDYQVHLGELEITLSPHFS
::::.::.. .:.:::.:.. :::::::::: . .. ..:. : .. :. .
NP_001 KWPWQVSLHFGTTHICGGTLIDAQWVLTAAHCFFVTREKVLEGWKVYAGTSNLHQLPEAA
340 350 360 370 380 390
110 120 130 140 150 160
pF1KE6 TVRQIILHSSPSGQPGTSGDIALVELSVPVTLSSRILPVCLPEASDDFCPGIRCWVTGWG
.. .::..:. . . ::::..:: :.:::..: :.::: .. : . ::.::.:
NP_001 SIAEIIINSNYTDEEDDY-DIALMRLSKPLTLSAHIHPACLPMHGQTFSLNETCWITGFG
400 410 420 430 440 450
170 180 190 200 210 220
pF1KE6 YTREGEPLPPPYSLREVKVSVVDTETCRRDYPGPGGSILQPDMLCA---RGPGDACQDDS
::: . :. ::::.:...: . : :: : : : :.:: :: :.:: ::
NP_001 KTRETDDKTSPF-LREVQVNLIDFKKCN-DYL-VYDSYLTPRMMCAGDLRGGRDSCQGDS
460 470 480 490 500 510
230 240 250 260 270 280
pF1KE6 GGPLVCQVNGAWVQAGIVSWGEGCGRPNRPGVYTRVPAYVNWIRRHITASGGSESGYPRL
::::::. :. : ::..::: :::. :.:::::.: . :: .. .:.:
NP_001 GGPLVCEQNNRWYLAGVTSWGTGCGQRNKPGVYTKVTEVLPWIYSKMESSAG
520 530 540 550 560
290 300 310 320
pF1KE6 PLLAGFFLPGLFLLLVSCVLLAKCLLHPSADGTPFPAPD
>>NP_001193718 (OMIM: 610050) transmembrane protease ser (532 aa)
initn: 562 init1: 355 opt: 704 Z-score: 767.1 bits: 150.9 E(85289): 5.5e-36
Smith-Waterman score: 704; 43.1% identity (66.8% similar) in 253 aa overlap (18-265:271-519)
10 20 30 40
pF1KE6 MALGACGLLLLLAVPGVSLRTLQPGCGRPQVSDAGGRIVGGHAAPAG
: : .. :.. . :::::: : .
NP_001 EVAHRDFANSFSILRYNSTIQESLHRSECPSQRYISLQCSHCGLRAMTGRIVGGALASDS
250 260 270 280 290 300
50 60 70 80 90 100
pF1KE6 AWPWQASLRLRRVHVCGGSLLSPQWVLTAAHCFSGSLNS--SDYQVHLGELEITLSPHFS
::::.::.. .:.:::.:.. :::::::::: . .. ..:. : .. :. .
NP_001 KWPWQVSLHFGTTHICGGTLIDAQWVLTAAHCFFVTREKVLEGWKVYAGTSNLHQLPEAA
310 320 330 340 350 360
110 120 130 140 150 160
pF1KE6 TVRQIILHSSPSGQPGTSGDIALVELSVPVTLSSRILPVCLPEASDDFCPGIRCWVTGWG
.. .::..:. . . ::::..:: :.:::..: :.::: .. : . ::.::.:
NP_001 SIAEIIINSNYTDEEDDY-DIALMRLSKPLTLSAHIHPACLPMHGQTFSLNETCWITGFG
370 380 390 400 410
170 180 190 200 210 220
pF1KE6 YTREGEPLPPPYSLREVKVSVVDTETCRRDYPGPGGSILQPDMLCA---RGPGDACQDDS
::: . :. ::::.:...: . : :: : : : :.:: :: :.:: ::
NP_001 KTRETDDKTSPF-LREVQVNLIDFKKCN-DYL-VYDSYLTPRMMCAGDLRGGRDSCQGDS
420 430 440 450 460 470
230 240 250 260 270 280
pF1KE6 GGPLVCQVNGAWVQAGIVSWGEGCGRPNRPGVYTRVPAYVNWIRRHITASGGSESGYPRL
::::::. :. : ::..::: :::. :.:::::.: . ::
NP_001 GGPLVCEQNNRWYLAGVTSWGTGCGQRNKPGVYTKVTEVLPWIYSKMESEVRFRKS
480 490 500 510 520 530
290 300 310 320
pF1KE6 PLLAGFFLPGLFLLLVSCVLLAKCLLHPSADGTPFPAPD
>>NP_001070731 (OMIM: 610050) transmembrane protease ser (567 aa)
initn: 562 init1: 355 opt: 704 Z-score: 766.7 bits: 150.9 E(85289): 5.8e-36
Smith-Waterman score: 704; 43.1% identity (66.8% similar) in 253 aa overlap (18-265:306-554)
10 20 30 40
pF1KE6 MALGACGLLLLLAVPGVSLRTLQPGCGRPQVSDAGGRIVGGHAAPAG
: : .. :.. . :::::: : .
NP_001 EVAHRDFANSFSILRYNSTIQESLHRSECPSQRYISLQCSHCGLRAMTGRIVGGALASDS
280 290 300 310 320 330
50 60 70 80 90 100
pF1KE6 AWPWQASLRLRRVHVCGGSLLSPQWVLTAAHCFSGSLNS--SDYQVHLGELEITLSPHFS
::::.::.. .:.:::.:.. :::::::::: . .. ..:. : .. :. .
NP_001 KWPWQVSLHFGTTHICGGTLIDAQWVLTAAHCFFVTREKVLEGWKVYAGTSNLHQLPEAA
340 350 360 370 380 390
110 120 130 140 150 160
pF1KE6 TVRQIILHSSPSGQPGTSGDIALVELSVPVTLSSRILPVCLPEASDDFCPGIRCWVTGWG
.. .::..:. . . ::::..:: :.:::..: :.::: .. : . ::.::.:
NP_001 SIAEIIINSNYTDEEDDY-DIALMRLSKPLTLSAHIHPACLPMHGQTFSLNETCWITGFG
400 410 420 430 440 450
170 180 190 200 210 220
pF1KE6 YTREGEPLPPPYSLREVKVSVVDTETCRRDYPGPGGSILQPDMLCA---RGPGDACQDDS
::: . :. ::::.:...: . : :: : : : :.:: :: :.:: ::
NP_001 KTRETDDKTSPF-LREVQVNLIDFKKCN-DYL-VYDSYLTPRMMCAGDLRGGRDSCQGDS
460 470 480 490 500 510
230 240 250 260 270 280
pF1KE6 GGPLVCQVNGAWVQAGIVSWGEGCGRPNRPGVYTRVPAYVNWIRRHITASGGSESGYPRL
::::::. :. : ::..::: :::. :.:::::.: . ::
NP_001 GGPLVCEQNNRWYLAGVTSWGTGCGQRNKPGVYTKVTEVLPWIYSKMESEVRFRKS
520 530 540 550 560
290 300 310 320
pF1KE6 PLLAGFFLPGLFLLLVSCVLLAKCLLHPSADGTPFPAPD
321 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Nov 8 12:25:00 2016 done: Tue Nov 8 12:25:01 2016
Total Scan time: 7.680 Total Display time: 0.000
Function used was FASTA [36.3.4 Apr, 2011]