Result of FASTA (omim) for
pFN21AE6349
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE6349, 390 aa
1>>>pF1KE6349 390 - 390 aa - 390 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.0892+/-0.000383; mu= 18.4662+/- 0.024
mean_var=65.0376+/-13.416, 0's: 0 Z-trim(112.8): 37 B-trim: 1066 in 1/51
Lambda= 0.159035
statistics sampled from 21776 (21812) to 21776 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.625), E-opt: 0.2 (0.256), width: 16
Scan time: 7.110
The best scores are: opt bits E(85289)
NP_003991 (OMIM: 601526) chitinase-3-like protein ( 390) 2611 607.9 1.3e-173
NP_001020368 (OMIM: 601526) chitinase-3-like prote ( 380) 2469 575.3 8.4e-164
NP_001020370 (OMIM: 601526) chitinase-3-like prote ( 311) 2080 486.0 5.2e-137
NP_003456 (OMIM: 600031,614122) chitotriosidase-1 ( 466) 1411 332.6 1.2e-90
NP_001267 (OMIM: 181500,601525,611960) chitinase-3 ( 383) 1371 323.4 5.8e-88
NP_970615 (OMIM: 606080) acidic mammalian chitinas ( 476) 1310 309.4 1.1e-83
NP_002548 (OMIM: 603578) oviduct-specific glycopro ( 678) 1161 275.3 2.9e-73
NP_001243054 (OMIM: 600031,614122) chitotriosidase ( 447) 1045 248.6 2.2e-65
NP_001244930 (OMIM: 606080) acidic mammalian chiti ( 368) 936 223.5 6.2e-58
XP_016856537 (OMIM: 606080) PREDICTED: acidic mamm ( 368) 936 223.5 6.2e-58
NP_068569 (OMIM: 606080) acidic mammalian chitinas ( 368) 936 223.5 6.2e-58
NP_001244932 (OMIM: 606080) acidic mammalian chiti ( 368) 936 223.5 6.2e-58
XP_016856536 (OMIM: 606080) PREDICTED: acidic mamm ( 315) 789 189.8 7.8e-48
NP_001244931 (OMIM: 606080) acidic mammalian chiti ( 315) 789 189.8 7.8e-48
XP_006710640 (OMIM: 606080) PREDICTED: acidic mamm ( 315) 789 189.8 7.8e-48
NP_001244934 (OMIM: 606080) acidic mammalian chiti ( 315) 789 189.8 7.8e-48
NP_001035713 (OMIM: 606080) acidic mammalian chiti ( 315) 789 189.8 7.8e-48
NP_001244933 (OMIM: 606080) acidic mammalian chiti ( 315) 789 189.8 7.8e-48
NP_001257438 (OMIM: 600031,614122) chitotriosidase ( 421) 511 126.1 1.6e-28
>>NP_003991 (OMIM: 601526) chitinase-3-like protein 2 is (390 aa)
initn: 2611 init1: 2611 opt: 2611 Z-score: 3237.7 bits: 607.9 E(85289): 1.3e-173
Smith-Waterman score: 2611; 99.7% identity (100.0% similar) in 390 aa overlap (1-390:1-390)
10 20 30 40 50 60
pF1KE6 MGATTMDQKSLWAGVVVLLLLQGGSAYKLVCYFTNWSQDRQEPGKFTPENIDPFLCSHLI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 MGATTMDQKSLWAGVVVLLLLQGGSAYKLVCYFTNWSQDRQEPGKFTPENIDPFLCSHLI
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 YSFASIENNKVIIKDKSEVMLYQTINSLKTKNPKLKILLSIGGYLFGSKGFHPMVDSSTS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 YSFASIENNKVIIKDKSEVMLYQTINSLKTKNPKLKILLSIGGYLFGSKGFHPMVDSSTS
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 RLEFINSIILFLRNHNFDGLDVSWIYPDQKENTHFTVLIHELAEAFQKDFTKSTKERLLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 RLEFINSIILFLRNHNFDGLDVSWIYPDQKENTHFTVLIHELAEAFQKDFTKSTKERLLL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE6 TVGVSAGRQMIDNSYQVEKLAKDLDFINLLSFDFHGSWEKPLITGHNSPLSKGWQDRGPS
:.::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 TAGVSAGRQMIDNSYQVEKLAKDLDFINLLSFDFHGSWEKPLITGHNSPLSKGWQDRGPS
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE6 SYYNVEYAVGYWIHKGMPSEKVVMGIPTYGHSFTLASAETTVGAPASGPGAAGPITESSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 SYYNVEYAVGYWIHKGMPSEKVVMGIPTYGHSFTLASAETTVGAPASGPGAAGPITESSG
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE6 FLAYYEICQFLKGAKITRLQDQQVPYAVKGNQWVGYDDVKSMETKVQFLKNLNLGGAMIW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_003 FLAYYEICQFLKGAKITRLQDQQVPYAVKGNQWVGYDDVKSMETKVQFLKNLNLGGAMIW
310 320 330 340 350 360
370 380 390
pF1KE6 SIDMDDFTGKSCNQGPYPLVQAVKRSLGSL
::::::::::::::::::::::::::::::
NP_003 SIDMDDFTGKSCNQGPYPLVQAVKRSLGSL
370 380 390
>>NP_001020368 (OMIM: 601526) chitinase-3-like protein 2 (380 aa)
initn: 2469 init1: 2469 opt: 2469 Z-score: 3061.8 bits: 575.3 E(85289): 8.4e-164
Smith-Waterman score: 2523; 97.2% identity (97.4% similar) in 390 aa overlap (1-390:1-380)
10 20 30 40 50 60
pF1KE6 MGATTMDQKSLWAGVVVLLLLQGGSAYKLVCYFTNWSQDRQEPGKFTPENIDPFLCSHLI
:::::::::::::: ::::::::::::::::::::::::::::::::::::
NP_001 MGATTMDQKSLWAG----------SAYKLVCYFTNWSQDRQEPGKFTPENIDPFLCSHLI
10 20 30 40 50
70 80 90 100 110 120
pF1KE6 YSFASIENNKVIIKDKSEVMLYQTINSLKTKNPKLKILLSIGGYLFGSKGFHPMVDSSTS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YSFASIENNKVIIKDKSEVMLYQTINSLKTKNPKLKILLSIGGYLFGSKGFHPMVDSSTS
60 70 80 90 100 110
130 140 150 160 170 180
pF1KE6 RLEFINSIILFLRNHNFDGLDVSWIYPDQKENTHFTVLIHELAEAFQKDFTKSTKERLLL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RLEFINSIILFLRNHNFDGLDVSWIYPDQKENTHFTVLIHELAEAFQKDFTKSTKERLLL
120 130 140 150 160 170
190 200 210 220 230 240
pF1KE6 TVGVSAGRQMIDNSYQVEKLAKDLDFINLLSFDFHGSWEKPLITGHNSPLSKGWQDRGPS
:.::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TAGVSAGRQMIDNSYQVEKLAKDLDFINLLSFDFHGSWEKPLITGHNSPLSKGWQDRGPS
180 190 200 210 220 230
250 260 270 280 290 300
pF1KE6 SYYNVEYAVGYWIHKGMPSEKVVMGIPTYGHSFTLASAETTVGAPASGPGAAGPITESSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 SYYNVEYAVGYWIHKGMPSEKVVMGIPTYGHSFTLASAETTVGAPASGPGAAGPITESSG
240 250 260 270 280 290
310 320 330 340 350 360
pF1KE6 FLAYYEICQFLKGAKITRLQDQQVPYAVKGNQWVGYDDVKSMETKVQFLKNLNLGGAMIW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FLAYYEICQFLKGAKITRLQDQQVPYAVKGNQWVGYDDVKSMETKVQFLKNLNLGGAMIW
300 310 320 330 340 350
370 380 390
pF1KE6 SIDMDDFTGKSCNQGPYPLVQAVKRSLGSL
::::::::::::::::::::::::::::::
NP_001 SIDMDDFTGKSCNQGPYPLVQAVKRSLGSL
360 370 380
>>NP_001020370 (OMIM: 601526) chitinase-3-like protein 2 (311 aa)
initn: 2080 init1: 2080 opt: 2080 Z-score: 2580.7 bits: 486.0 E(85289): 5.2e-137
Smith-Waterman score: 2080; 99.7% identity (100.0% similar) in 311 aa overlap (80-390:1-311)
50 60 70 80 90 100
pF1KE6 NIDPFLCSHLIYSFASIENNKVIIKDKSEVMLYQTINSLKTKNPKLKILLSIGGYLFGSK
::::::::::::::::::::::::::::::
NP_001 MLYQTINSLKTKNPKLKILLSIGGYLFGSK
10 20 30
110 120 130 140 150 160
pF1KE6 GFHPMVDSSTSRLEFINSIILFLRNHNFDGLDVSWIYPDQKENTHFTVLIHELAEAFQKD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GFHPMVDSSTSRLEFINSIILFLRNHNFDGLDVSWIYPDQKENTHFTVLIHELAEAFQKD
40 50 60 70 80 90
170 180 190 200 210 220
pF1KE6 FTKSTKERLLLTVGVSAGRQMIDNSYQVEKLAKDLDFINLLSFDFHGSWEKPLITGHNSP
::::::::::::.:::::::::::::::::::::::::::::::::::::::::::::::
NP_001 FTKSTKERLLLTAGVSAGRQMIDNSYQVEKLAKDLDFINLLSFDFHGSWEKPLITGHNSP
100 110 120 130 140 150
230 240 250 260 270 280
pF1KE6 LSKGWQDRGPSSYYNVEYAVGYWIHKGMPSEKVVMGIPTYGHSFTLASAETTVGAPASGP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LSKGWQDRGPSSYYNVEYAVGYWIHKGMPSEKVVMGIPTYGHSFTLASAETTVGAPASGP
160 170 180 190 200 210
290 300 310 320 330 340
pF1KE6 GAAGPITESSGFLAYYEICQFLKGAKITRLQDQQVPYAVKGNQWVGYDDVKSMETKVQFL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GAAGPITESSGFLAYYEICQFLKGAKITRLQDQQVPYAVKGNQWVGYDDVKSMETKVQFL
220 230 240 250 260 270
350 360 370 380 390
pF1KE6 KNLNLGGAMIWSIDMDDFTGKSCNQGPYPLVQAVKRSLGSL
:::::::::::::::::::::::::::::::::::::::::
NP_001 KNLNLGGAMIWSIDMDDFTGKSCNQGPYPLVQAVKRSLGSL
280 290 300 310
>>NP_003456 (OMIM: 600031,614122) chitotriosidase-1 isof (466 aa)
initn: 1415 init1: 530 opt: 1411 Z-score: 1748.6 bits: 332.6 E(85289): 1.2e-90
Smith-Waterman score: 1411; 52.1% identity (80.6% similar) in 382 aa overlap (12-387:7-385)
10 20 30 40 50 60
pF1KE6 MGATTMDQKSLWAGVVVLLLLQGGSAYKLVCYFTNWSQDRQEPGKFTPENIDPFLCSHLI
::: .:::.. ::: :::::::::.: :: ..: :...:: ::.:::
NP_003 MVRSVAWAGFMVLLMIPWGSAAKLVCYFTNWAQYRQGEARFLPKDLDPSLCTHLI
10 20 30 40 50
70 80 90 100 110 120
pF1KE6 YSFASIENNKVIIKDKSEVMLYQTINSLKTKNPKLKILLSIGGYLFGSKGFHPMVDSSTS
:.::.. :... . .. ::: .:.:: ::::: ::.:::. ::.. : :: ....
NP_003 YAFAGMTNHQLSTTEWNDETLYQEFNGLKKMNPKLKTLLAIGGWNFGTQKFTDMVATANN
60 70 80 90 100 110
130 140 150 160 170
pF1KE6 RLEFINSIILFLRNHNFDGLDVSWIYPDQK-----ENTHFTVLIHELAEAFQKDFTKSTK
: :.:: : :::...:::::..: :: .. .. .::.:...::.:::.. : :
NP_003 RQTFVNSAIRFLRKYSFDGLDLDWEYPGSQGSPAVDKERFTTLVQDLANAFQQEAQTSGK
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE6 ERLLLTVGVSAGRQMIDNSYQVEKLAKDLDFINLLSFDFHGSWEKPLITGHNSPLSKGWQ
:::::...: ::. ..: .:.:.:.:..:::.::...:::::::: .::::::: : .
NP_003 ERLLLSAAVPAGQTYVDAGYEVDKIAQNLDFVNLMAYDFHGSWEK--VTGHNSPLYKRQE
180 190 200 210 220 230
240 250 260 270 280 290
pF1KE6 DRGPSSYYNVEYAVGYWIHKGMPSEKVVMGIPTYGHSFTLASA-ETTVGAPASGPGAAGP
. : .. ::. :: :..:: :. :...:.::::.::::::. .: :::::.: :. ::
NP_003 ESGAAASLNVDAAVQQWLQKGTPASKLILGMPTYGRSFTLASSSDTRVGAPATGSGTPGP
240 250 260 270 280 290
300 310 320 330 340 350
pF1KE6 ITESSGFLAYYEICQFLKGAKITRLQDQQVPYAVKGNQWVGYDDVKSMETKVQFLKNLNL
.:. .:.:::::.:.. ::: :.:::.::: . :::::.:::.:..:::..::. .:
NP_003 FTKEGGMLAYYEVCSW-KGATKQRIQDQKVPYIFRDNQWVGFDDVESFKTKVSYLKQKGL
300 310 320 330 340 350
360 370 380 390
pF1KE6 GGAMIWSIDMDDFTGKSCNQGPYPLVQAVKRSLGSL
::::.:..:.:::.: ::::: :::.:.... :
NP_003 GGAMVWALDLDDFAGFSCNQGRYPLIQTLRQELSLPYLPSGTPELEVPKPGQPSEPEHGP
360 370 380 390 400 410
NP_003 SPGQDTFCQGKADGLYPNPRERSSFYSCAAGRLFQQSCPTGLVFSNSCKCCTWN
420 430 440 450 460
>>NP_001267 (OMIM: 181500,601525,611960) chitinase-3-lik (383 aa)
initn: 1351 init1: 656 opt: 1371 Z-score: 1700.2 bits: 323.4 E(85289): 5.8e-88
Smith-Waterman score: 1371; 50.9% identity (80.0% similar) in 385 aa overlap (6-389:1-382)
10 20 30 40 50 60
pF1KE6 MGATTMDQKSLWAGVVVLLLLQGGSAYKLVCYFTNWSQDRQEPGKFTPENIDPFLCSHLI
: :. .: :::.::: ::::::::.:.::: :. :. :. .: :::.:.:
NP_001 MGVKASQTGFVVLVLLQCCSAYKLVCYYTSWSQYREGDGSCFPDALDRFLCTHII
10 20 30 40 50
70 80 90 100 110 120
pF1KE6 YSFASIENNKVIIKDKSEVMLYQTINSLKTKNPKLKILLSIGGYLFGSKGFHPMVDSSTS
::::.: :... . ..: :: .:.::..::.:: :::.::. :::. : ..... :
NP_001 YSFANISNDHIDTWEWNDVTLYGMLNTLKNRNPNLKTLLSVGGWNFGSQRFSKIASNTQS
60 70 80 90 100 110
130 140 150 160 170 180
pF1KE6 RLEFINSIILFLRNHNFDGLDVSWIYPDQKENTHFTVLIHELAEAFQKDFTKSTKERLLL
: ::.:. :::.:.:::::..:.:: .... :::.::.:. : :. .. :..:::
NP_001 RRTFIKSVPPFLRTHGFDGLDLAWLYPGRRDKQHFTTLIKEMKAEFIKE-AQPGKKQLLL
120 130 140 150 160 170
190 200 210 220 230 240
pF1KE6 TVGVSAGRQMIDNSYQVEKLAKDLDFINLLSFDFHGSWEKPLITGHNSPLSKGWQDRGPS
....:::. ::.::.. :... ::::.....::::.:. :::.::: .: .: .:.
NP_001 SAALSAGKVTIDSSYDIAKISQHLDFISIMTYDFHGAWRGT--TGHHSPLFRGQEDASPD
180 190 200 210 220 230
250 260 270 280 290 300
pF1KE6 SYYNVEYAVGYWIHKGMPSEKVVMGIPTYGHSFTLASAETTVGAPASGPGAAGPITESSG
. :..::::: .. : :. :.::::::.:.::::::.:: :::: :::: : .:. .:
NP_001 RFSNTDYAVGYMLRLGAPASKLVMGIPTFGRSFTLASSETGVGAPISGPGIPGRFTKEAG
240 250 260 270 280 290
310 320 330 340 350 360
pF1KE6 FLAYYEICQFLKGAKITRLQDQQVPYAVKGNQWVGYDDVKSMETKVQFLKNLNLGGAMIW
:::::::.::.:: . :. ::::::.:::::::::: .:...:::.::. .:.:::.:
NP_001 TLAYYEICDFLRGATVHRILGQQVPYATKGNQWVGYDDQESVKSKVQYLKDRQLAGAMVW
300 310 320 330 340 350
370 380 390
pF1KE6 SIDMDDFTGKSCNQG-PYPLVQAVKRSLGSL
..:.::: :. :.: .::..:.: .:..
NP_001 ALDLDDFQGSFCGQDLRFPLTNAIKDALAAT
360 370 380
>>NP_970615 (OMIM: 606080) acidic mammalian chitinase is (476 aa)
initn: 884 init1: 481 opt: 1310 Z-score: 1623.2 bits: 309.4 E(85289): 1.1e-83
Smith-Waterman score: 1310; 49.0% identity (77.9% similar) in 390 aa overlap (6-388:1-388)
10 20 30 40 50 60
pF1KE6 MGATTMDQKSLWAGVVVLLLLQGGSAYKLVCYFTNWSQDRQEPGKFTPENIDPFLCSHLI
: . : .:.:..: :: ::::.:.::::::.: : :.: :.:::: ::.:::
NP_970 MTKLILLTGLVLILNLQLGSAYQLTCYFTNWAQYRPGLGRFMPDNIDPCLCTHLI
10 20 30 40 50
70 80 90 100 110 120
pF1KE6 YSFASIENNKVIIKDKSEVMLYQTINSLKTKNPKLKILLSIGGYLFGSKGFHPMVDSSTS
:.::. .::.. . ..: :::..:.::.:: .:: ::.:::. ::. : ::.. .
NP_970 YAFAGRQNNEITTIEWNDVTLYQAFNGLKNKNSQLKTLLAIGGWNFGTAPFTAMVSTPEN
60 70 80 90 100 110
130 140 150 160 170
pF1KE6 RLEFINSIILFLRNHNFDGLDVSWIYPDQK----ENTH-FTVLIHELAEAFQKDFTKSTK
: ::.:.: :::...::::: .: :: .. .. : ::::..:. :::... . .:
NP_970 RQTFITSVIKFLRQYEFDGLDFDWEYPGSRGSPPQDKHLFTVLVQEMREAFEQEAKQINK
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE6 ERLLLTVGVSAGRQMIDNSYQVEKLAKDLDFINLLSFDFHGSWEKPLITGHNSPLSKGWQ
::..:..:.:: . :...:.. .:.. ::.:.....:.::::: ::.:::: :
NP_970 PRLMVTAAVAAGISNIQSGYEIPQLSQYLDYIHVMTYDLHGSWEG--YTGENSPLYKYPT
180 190 200 210 220 230
240 250 260 270 280 290
pF1KE6 DRGPSSYYNVEYAVGYWIHKGMPSEKVVMGIPTYGHSFTLAS-AETTVGAPASGPGAAGP
: : ..: ::.:...:: .: :.::...:.:::::.: :.. ..: .:::.:: : :::
NP_970 DTGSNAYLNVDYVMNYWKDNGAPAEKLIVGFPTYGHNFILSNPSNTGIGAPTSGAGPAGP
240 250 260 270 280 290
300 310 320 330 340 350
pF1KE6 ITESSGFLAYYEICQFLK-GAKITRLQDQQVPYAVKGNQWVGYDDVKSMETKVQFLKNLN
.. ::. :::::: ::: :: :.:::: .:: :::::..::.. :.:.::. .
NP_970 YAKESGIWAYYEICTFLKNGATQGWDAPQEVPYAYQGNVWVGYDNIKSFDIKAQWLKHNK
300 310 320 330 340 350
360 370 380 390
pF1KE6 LGGAMIWSIDMDDFTGKSCNQGPYPLVQAVKRSLGSL
.::::.:.::.::::: :::: .::....:..::
NP_970 FGGAMVWAIDLDDFTGTFCNQGKFPLISTLKKALGLQSASCTAPAQPIEPITAAPSGSGN
360 370 380 390 400 410
NP_970 GSGSSSSGGSSGGSGFCAVRANGLYPVANNRNAFWHCVNGVTYQQNCQAGLVFDTSCDCC
420 430 440 450 460 470
>>NP_002548 (OMIM: 603578) oviduct-specific glycoprotein (678 aa)
initn: 417 init1: 417 opt: 1161 Z-score: 1436.2 bits: 275.3 E(85289): 2.9e-73
Smith-Waterman score: 1161; 47.2% identity (76.4% similar) in 377 aa overlap (11-380:6-375)
10 20 30 40 50 60
pF1KE6 MGATTMDQKSLWAGVVVLLLLQGGSAYKLVCYFTNWSQDRQEPGKFTPENIDPFLCSHLI
::.:.:..: . :.:.:::::::::...: :... :...:::::.:::
NP_002 MWKLLLWVGLVLVLKHHDGAAHKLVCYFTNWAHSRPGPASILPHDLDPFLCTHLI
10 20 30 40 50
70 80 90 100 110
pF1KE6 YSFASIENNKVIIKD-KSEVMLYQTINSLKTKNPKLKILLSIGGYLFGSKGFHPMVDSST
..:::..::... :: ..: .:: .:.:: .: .:: ::::::. ::.. : :... .
NP_002 FAFASMNNNQIVAKDLQDEKILYPEFNKLKERNRELKTLLSIGGWNFGTSRFTTMLSTFA
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE6 SRLEFINSIILFLRNHNFDGLDVSWIYPDQKENT-H----FTVLIHELAEAFQKDFTKST
.: .:: :.: .::.:.:::::. ..:: . . : : ::.:: ::.:. .
NP_002 NREKFIASVISLLRTHDFDGLDLFFLYPGLRGSPMHDRWTFLFLIEELLFAFRKEALLTM
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE6 KERLLLTVGVSAGRQMIDNSYQVEKLAKDLDFINLLSFDFHGSWEKPLITGHNSPLSKGW
. ::::...::. .....::.:. :.. :::::.::.:.:::::. .::::::: .
NP_002 RPRLLLSAAVSGVPHIVQTSYDVRFLGRLLDFINVLSYDLHGSWER--FTGHNSPLFSLP
180 190 200 210 220 230
240 250 260 270 280 290
pF1KE6 QDRGPSSYYNVEYAVGYWIHKGMPSEKVVMGIPTYGHSFTLASA-ETTVGAPASGPGAAG
.: :.: ::..:: . : ::::..:::::::..: : .: .. . : : ::.. :
NP_002 ED--PKSS---AYAMNYWRKLGAPSEKLIMGIPTYGRTFRLLKASKNGLQARAIGPASPG
240 250 260 270 280
300 310 320 330 340 350
pF1KE6 PITESSGFLAYYEICQFLKGAKITRLQDQQVPYAVKGNQWVGYDDVKSMETKVQFLKNLN
:.. :::::.:::.:. ::: .. : :::: ::..:::::.. :. :. :.. .
NP_002 KYTKQEGFLAYFEICSFVWGAKKHWIDYQYVPYANKGKEWVGYDNAISFSYKAWFIRREH
290 300 310 320 330 340
360 370 380 390
pF1KE6 LGGAMIWSIDMDDFTGKSCNQGPYPLVQAVKRSLGSL
.::::.:..:::: : :. ::.:::
NP_002 FGGAMVWTLDMDDVRGTFCGTGPFPLVYVLNDILVRAEFSSTSLPQFWLSSAVNSSSTDP
350 360 370 380 390 400
>>NP_001243054 (OMIM: 600031,614122) chitotriosidase-1 i (447 aa)
initn: 1326 init1: 530 opt: 1045 Z-score: 1295.0 bits: 248.6 E(85289): 2.2e-65
Smith-Waterman score: 1288; 49.2% identity (76.7% similar) in 382 aa overlap (12-387:7-366)
10 20 30 40 50 60
pF1KE6 MGATTMDQKSLWAGVVVLLLLQGGSAYKLVCYFTNWSQDRQEPGKFTPENIDPFLCSHLI
::: .:::.. ::: :::::::::.: :: ..: :...:: ::.:::
NP_001 MVRSVAWAGFMVLLMIPWGSAAKLVCYFTNWAQYRQGEARFLPKDLDPSLCTHLI
10 20 30 40 50
70 80 90 100 110 120
pF1KE6 YSFASIENNKVIIKDKSEVMLYQTINSLKTKNPKLKILLSIGGYLFGSKGFHPMVDSSTS
:.::.. :... . .. ::: .:.:: : : :: ....
NP_001 YAFAGMTNHQLSTTEWNDETLYQEFNGLK-------------------KMFTDMVATANN
60 70 80 90
130 140 150 160 170
pF1KE6 RLEFINSIILFLRNHNFDGLDVSWIYPDQK-----ENTHFTVLIHELAEAFQKDFTKSTK
: :.:: : :::...:::::..: :: .. .. .::.:...::.:::.. : :
NP_001 RQTFVNSAIRFLRKYSFDGLDLDWEYPGSQGSPAVDKERFTTLVQDLANAFQQEAQTSGK
100 110 120 130 140 150
180 190 200 210 220 230
pF1KE6 ERLLLTVGVSAGRQMIDNSYQVEKLAKDLDFINLLSFDFHGSWEKPLITGHNSPLSKGWQ
:::::...: ::. ..: .:.:.:.:..:::.::...:::::::: .::::::: : .
NP_001 ERLLLSAAVPAGQTYVDAGYEVDKIAQNLDFVNLMAYDFHGSWEK--VTGHNSPLYKRQE
160 170 180 190 200 210
240 250 260 270 280 290
pF1KE6 DRGPSSYYNVEYAVGYWIHKGMPSEKVVMGIPTYGHSFTLASA-ETTVGAPASGPGAAGP
. : .. ::. :: :..:: :. :...:.::::.::::::. .: :::::.: :. ::
NP_001 ESGAAASLNVDAAVQQWLQKGTPASKLILGMPTYGRSFTLASSSDTRVGAPATGSGTPGP
220 230 240 250 260 270
300 310 320 330 340 350
pF1KE6 ITESSGFLAYYEICQFLKGAKITRLQDQQVPYAVKGNQWVGYDDVKSMETKVQFLKNLNL
.:. .:.:::::.:.. ::: :.:::.::: . :::::.:::.:..:::..::. .:
NP_001 FTKEGGMLAYYEVCSW-KGATKQRIQDQKVPYIFRDNQWVGFDDVESFKTKVSYLKQKGL
280 290 300 310 320 330
360 370 380 390
pF1KE6 GGAMIWSIDMDDFTGKSCNQGPYPLVQAVKRSLGSL
::::.:..:.:::.: ::::: :::.:.... :
NP_001 GGAMVWALDLDDFAGFSCNQGRYPLIQTLRQELSLPYLPSGTPELEVPKPGQPSEPEHGP
340 350 360 370 380 390
NP_001 SPGQDTFCQGKADGLYPNPRERSSFYSCAAGRLFQQSCPTGLVFSNSCKCCTWN
400 410 420 430 440
>>NP_001244930 (OMIM: 606080) acidic mammalian chitinase (368 aa)
initn: 533 init1: 417 opt: 936 Z-score: 1161.1 bits: 223.5 E(85289): 6.2e-58
Smith-Waterman score: 936; 47.9% identity (78.4% similar) in 282 aa overlap (114-388:1-280)
90 100 110 120 130 140
pF1KE6 TINSLKTKNPKLKILLSIGGYLFGSKGFHPMVDSSTSRLEFINSIILFLRNHNFDGLDVS
::.. .: ::.:.: :::...::::: .
NP_001 MVSTPENRQTFITSVIKFLRQYEFDGLDFD
10 20 30
150 160 170 180 190
pF1KE6 WIYPDQK----ENTH-FTVLIHELAEAFQKDFTKSTKERLLLTVGVSAGRQMIDNSYQVE
: :: .. .. : ::::..:. :::... . .: ::..:..:.:: . :...:..
NP_001 WEYPGSRGSPPQDKHLFTVLVQEMREAFEQEAKQINKPRLMVTAAVAAGISNIQSGYEIP
40 50 60 70 80 90
200 210 220 230 240 250
pF1KE6 KLAKDLDFINLLSFDFHGSWEKPLITGHNSPLSKGWQDRGPSSYYNVEYAVGYWIHKGMP
.:.. ::.:.....:.::::: ::.:::: : : : ..: ::.:...:: .: :
NP_001 QLSQYLDYIHVMTYDLHGSWEG--YTGENSPLYKYPTDTGSNAYLNVDYVMNYWKDNGAP
100 110 120 130 140
260 270 280 290 300 310
pF1KE6 SEKVVMGIPTYGHSFTLAS-AETTVGAPASGPGAAGPITESSGFLAYYEICQFLK-GAKI
.::...:.:::::.: :.. ..: .:::.:: : ::: .. ::. :::::: ::: ::
NP_001 AEKLIVGFPTYGHNFILSNPSNTGIGAPTSGAGPAGPYAKESGIWAYYEICTFLKNGATQ
150 160 170 180 190 200
320 330 340 350 360 370
pF1KE6 TRLQDQQVPYAVKGNQWVGYDDVKSMETKVQFLKNLNLGGAMIWSIDMDDFTGKSCNQGP
:.:::: .:: :::::..::.. :.:.::. ..::::.:.::.::::: ::::
NP_001 GWDAPQEVPYAYQGNVWVGYDNIKSFDIKAQWLKHNKFGGAMVWAIDLDDFTGTFCNQGK
210 220 230 240 250 260
380 390
pF1KE6 YPLVQAVKRSLGSL
.::....:..::
NP_001 FPLISTLKKALGLQSASCTAPAQPIEPITAAPSGSGNGSGSSSSGGSSGGSGFCAVRANG
270 280 290 300 310 320
>>XP_016856537 (OMIM: 606080) PREDICTED: acidic mammalia (368 aa)
initn: 533 init1: 417 opt: 936 Z-score: 1161.1 bits: 223.5 E(85289): 6.2e-58
Smith-Waterman score: 936; 47.9% identity (78.4% similar) in 282 aa overlap (114-388:1-280)
90 100 110 120 130 140
pF1KE6 TINSLKTKNPKLKILLSIGGYLFGSKGFHPMVDSSTSRLEFINSIILFLRNHNFDGLDVS
::.. .: ::.:.: :::...::::: .
XP_016 MVSTPENRQTFITSVIKFLRQYEFDGLDFD
10 20 30
150 160 170 180 190
pF1KE6 WIYPDQK----ENTH-FTVLIHELAEAFQKDFTKSTKERLLLTVGVSAGRQMIDNSYQVE
: :: .. .. : ::::..:. :::... . .: ::..:..:.:: . :...:..
XP_016 WEYPGSRGSPPQDKHLFTVLVQEMREAFEQEAKQINKPRLMVTAAVAAGISNIQSGYEIP
40 50 60 70 80 90
200 210 220 230 240 250
pF1KE6 KLAKDLDFINLLSFDFHGSWEKPLITGHNSPLSKGWQDRGPSSYYNVEYAVGYWIHKGMP
.:.. ::.:.....:.::::: ::.:::: : : : ..: ::.:...:: .: :
XP_016 QLSQYLDYIHVMTYDLHGSWEG--YTGENSPLYKYPTDTGSNAYLNVDYVMNYWKDNGAP
100 110 120 130 140
260 270 280 290 300 310
pF1KE6 SEKVVMGIPTYGHSFTLAS-AETTVGAPASGPGAAGPITESSGFLAYYEICQFLK-GAKI
.::...:.:::::.: :.. ..: .:::.:: : ::: .. ::. :::::: ::: ::
XP_016 AEKLIVGFPTYGHNFILSNPSNTGIGAPTSGAGPAGPYAKESGIWAYYEICTFLKNGATQ
150 160 170 180 190 200
320 330 340 350 360 370
pF1KE6 TRLQDQQVPYAVKGNQWVGYDDVKSMETKVQFLKNLNLGGAMIWSIDMDDFTGKSCNQGP
:.:::: .:: :::::..::.. :.:.::. ..::::.:.::.::::: ::::
XP_016 GWDAPQEVPYAYQGNVWVGYDNIKSFDIKAQWLKHNKFGGAMVWAIDLDDFTGTFCNQGK
210 220 230 240 250 260
380 390
pF1KE6 YPLVQAVKRSLGSL
.::....:..::
XP_016 FPLISTLKKALGLQSASCTAPAQPIEPITAAPSGSGNGSGSSSSGGSSGGSGFCAVRANG
270 280 290 300 310 320
390 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Nov 8 12:21:38 2016 done: Tue Nov 8 12:21:39 2016
Total Scan time: 7.110 Total Display time: 0.040
Function used was FASTA [36.3.4 Apr, 2011]