Result of FASTA (ccds) for
pFN21AE6348
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE6348, 331 aa
1>>>pF1KE6348 331 - 331 aa - 331 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.3612+/-0.000776; mu= 15.0534+/- 0.047
mean_var=57.6223+/-11.644, 0's: 0 Z-trim(106.3): 27 B-trim: 0 in 0/51
Lambda= 0.168958
statistics sampled from 8891 (8917) to 8891 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.658), E-opt: 0.2 (0.274), width: 16
Scan time: 1.830
The best scores are: opt bits E(32554)
CCDS193.1 AKR7A3 gene_id:22977|Hs108|chr1 ( 331) 2247 555.9 1.6e-158
CCDS194.1 AKR7A2 gene_id:8574|Hs108|chr1 ( 359) 1999 495.5 2.7e-140
CCDS56.1 KCNAB2 gene_id:8514|Hs108|chr1 ( 353) 267 73.3 3.3e-13
CCDS55.1 KCNAB2 gene_id:8514|Hs108|chr1 ( 367) 267 73.3 3.4e-13
CCDS55571.1 KCNAB2 gene_id:8514|Hs108|chr1 ( 300) 263 72.3 5.6e-13
CCDS33882.1 KCNAB1 gene_id:7881|Hs108|chr3 ( 401) 261 71.8 1e-12
CCDS3175.1 KCNAB1 gene_id:7881|Hs108|chr3 ( 408) 261 71.8 1e-12
CCDS3174.1 KCNAB1 gene_id:7881|Hs108|chr3 ( 419) 261 71.8 1.1e-12
>>CCDS193.1 AKR7A3 gene_id:22977|Hs108|chr1 (331 aa)
initn: 2247 init1: 2247 opt: 2247 Z-score: 2959.4 bits: 555.9 E(32554): 1.6e-158
Smith-Waterman score: 2247; 99.4% identity (100.0% similar) in 331 aa overlap (1-331:1-331)
10 20 30 40 50 60
pF1KE6 MSRQLSRARPATVLGAMEMGRRMDAPTSAAVTRAFLERGHTEIDTAFVYSEGQSETILGG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS19 MSRQLSRARPATVLGAMEMGRRMDAPTSAAVTRAFLERGHTEIDTAFVYSEGQSETILGG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 LGLRLGGSDCRVKIDTKAIPLFGNSLKPDSLRFQLETSLKRLQCPRVDLFYLHMPDHSTP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS19 LGLRLGGSDCRVKIDTKAIPLFGNSLKPDSLRFQLETSLKRLQCPRVDLFYLHMPDHSTP
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 VEETLRACHQLHQEGKFVELGLSNYAAWEVAEICTLCKSNGWILPTVYQGMYNAITRQVE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS19 VEETLRACHQLHQEGKFVELGLSNYAAWEVAEICTLCKSNGWILPTVYQGMYNAITRQVE
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE6 TELFPCLRHFGLRFYAFNPLAGGLLTGKYKYEDKDGKQPVGRFFGNTWAEMYRNRYWKEH
::::::::::::::::::::::::::::::::::.:::::::::::::::::::::::::
CCDS19 TELFPCLRHFGLRFYAFNPLAGGLLTGKYKYEDKNGKQPVGRFFGNTWAEMYRNRYWKEH
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE6 HFEGIALVEKALQAAYGASAPSMTSATLRWMYHHSQLQGAHGDAVILGMSSLEQLEQNLA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS19 HFEGIALVEKALQAAYGASAPSMTSATLRWMYHHSQLQGAHGDAVILGMSSLEQLEQNLA
250 260 270 280 290 300
310 320 330
pF1KE6 AAEEGPLEPAVVDAFNQAWHLVAHECPNYFR
::::::::::::::::::::::.::::::::
CCDS19 AAEEGPLEPAVVDAFNQAWHLVTHECPNYFR
310 320 330
>>CCDS194.1 AKR7A2 gene_id:8574|Hs108|chr1 (359 aa)
initn: 1994 init1: 1994 opt: 1999 Z-score: 2632.1 bits: 495.5 E(32554): 2.7e-140
Smith-Waterman score: 1999; 87.2% identity (95.2% similar) in 335 aa overlap (2-331:25-359)
10 20 30
pF1KE6 MSRQLSRARP-----ATVLGAMEMGRRMDAPTSAAVT
.: :. .:: :.:::.::::::::::.:::..
CCDS19 MLSAASRVVSRAAVHCALRSPPPEARALAMSRPPPPRVASVLGTMEMGRRMDAPASAAAV
10 20 30 40 50 60
40 50 60 70 80 90
pF1KE6 RAFLERGHTEIDTAFVYSEGQSETILGGLGLRLGGSDCRVKIDTKAIPLFGNSLKPDSLR
::::::::::.::::.::.:::::::::::: :::.:::::: ::: : :.::::::.:
CCDS19 RAFLERGHTELDTAFMYSDGQSETILGGLGLGLGGGDCRVKIATKANPWDGKSLKPDSVR
70 80 90 100 110 120
100 110 120 130 140 150
pF1KE6 FQLETSLKRLQCPRVDLFYLHMPDHSTPVEETLRACHQLHQEGKFVELGLSNYAAWEVAE
::::::::::::.::::::: :::.:::::::.::..::::::::::::::::.:::::
CCDS19 SQLETSLKRLQCPQVDLFYLHAPDHGTPVEETLHACQRLHQEGKFVELGLSNYASWEVAE
130 140 150 160 170 180
160 170 180 190 200 210
pF1KE6 ICTLCKSNGWILPTVYQGMYNAITRQVETELFPCLRHFGLRFYAFNPLAGGLLTGKYKYE
:::::::::::::::::::::: :::::::::::::::::::::.:::::::::::::::
CCDS19 ICTLCKSNGWILPTVYQGMYNATTRQVETELFPCLRHFGLRFYAYNPLAGGLLTGKYKYE
190 200 210 220 230 240
220 230 240 250 260 270
pF1KE6 DKDGKQPVGRFFGNTWAEMYRNRYWKEHHFEGIALVEKALQAAYGASAPSMTSATLRWMY
::::::::::::::.::: ::::.:::::::.::::::::::::::::::.:::.:::::
CCDS19 DKDGKQPVGRFFGNSWAETYRNRFWKEHHFEAIALVEKALQAAYGASAPSVTSAALRWMY
250 260 270 280 290 300
280 290 300 310 320 330
pF1KE6 HHSQLQGAHGDAVILGMSSLEQLEQNLAAAEEGPLEPAVVDAFNQAWHLVAHECPNYFR
:::::::::::::::::::::::::::::.:::::::::::::::::::::::::::::
CCDS19 HHSQLQGAHGDAVILGMSSLEQLEQNLAATEEGPLEPAVVDAFNQAWHLVAHECPNYFR
310 320 330 340 350
>>CCDS56.1 KCNAB2 gene_id:8514|Hs108|chr1 (353 aa)
initn: 222 init1: 109 opt: 267 Z-score: 350.6 bits: 73.3 E(32554): 3.3e-13
Smith-Waterman score: 291; 28.8% identity (57.2% similar) in 299 aa overlap (20-306:48-327)
10 20 30 40
pF1KE6 MSRQLSRARPATVLGAMEMGRRMDAPTSAAVTRAFLERGHTEIDTAFVY
:. : . .: :. . : . .::: ::
CCDS56 TGSPGMIYRNLGKSGLRVSCLGLGTWVTFGGQITDEMAEQLMTLAY-DNGINLFDTAEVY
20 30 40 50 60 70
50 60 70 80 90 100
pF1KE6 SEGQSETILGGLGLRLGGSDCRVKIDTKAIPLFGNSLKPDSLRFQ-----LETSLKRLQC
. :..:..::.. . : . : :: : :.. .: . :..::.:::
CCDS56 AAGKAEVVLGNIIKKKGWRRSSLVITTK-IFWGGKAETERGLSRKHIIEGLKASLERLQL
80 90 100 110 120 130
110 120 130 140 150 160
pF1KE6 PRVDLFYLHMPDHSTPVEETLRACHQLHQEGKFVELGLSNYAAWEVAEICTLCKSNGWIL
::. . . :: .::.:::.:: .. ..: . : : ... :. : .. .. .
CCDS56 EYVDVVFANRPDPNTPMEETVRAMTHVINQGMAMYWGTSRWSSMEIMEAYSVARQFNLTP
140 150 160 170 180 190
170 180 190 200 210 220
pF1KE6 PTVYQGMYNAITRQ-VETELFPCLRH-FGLRFYAFNPLAGGLLTGKYKYEDKDGKQPVGR
: :. :. . :. ::..: : : : .:. ....::: :...::: .: : .:
CCDS56 PICEQAEYHMFQREKVEVQL-PELFHKIGVGAMTWSPLACGIVSGKYD----SGIPPYSR
200 210 220 230 240 250
230 240 250 260 270
pF1KE6 --FFGNTWAEMYRNRYWKEHHFEGIALVEKALQAA---YGASAPSMTSATLRWMYHHSQL
. : : ... .:. . : . : ::: : . :... : : ..
CCDS56 ASLKGYQW---LKDKILSEEGRRQQAKL-KELQAIAERLGCTLPQLAIA---WCLRN---
260 270 280 290 300
280 290 300 310 320 330
pF1KE6 QGAHGDAVILGMSSLEQLEQNLAAAEEGPLEPAVVDAFNQAWHLVAHECPNYFR
.:. ..:.:: :. .:: .:..: . :
CCDS56 EGV--SSVLLGASNADQLMENIGAIQVLPKLSSSIIHEIDSILGNKPYSKKDYRS
310 320 330 340 350
>>CCDS55.1 KCNAB2 gene_id:8514|Hs108|chr1 (367 aa)
initn: 222 init1: 109 opt: 267 Z-score: 350.3 bits: 73.3 E(32554): 3.4e-13
Smith-Waterman score: 291; 28.8% identity (57.2% similar) in 299 aa overlap (20-306:62-341)
10 20 30 40
pF1KE6 MSRQLSRARPATVLGAMEMGRRMDAPTSAAVTRAFLERGHTEIDTAFVY
:. : . .: :. . : . .::: ::
CCDS55 PKRQLQFYRNLGKSGLRVSCLGLGTWVTFGGQITDEMAEQLMTLAY-DNGINLFDTAEVY
40 50 60 70 80 90
50 60 70 80 90 100
pF1KE6 SEGQSETILGGLGLRLGGSDCRVKIDTKAIPLFGNSLKPDSLRFQ-----LETSLKRLQC
. :..:..::.. . : . : :: : :.. .: . :..::.:::
CCDS55 AAGKAEVVLGNIIKKKGWRRSSLVITTK-IFWGGKAETERGLSRKHIIEGLKASLERLQL
100 110 120 130 140
110 120 130 140 150 160
pF1KE6 PRVDLFYLHMPDHSTPVEETLRACHQLHQEGKFVELGLSNYAAWEVAEICTLCKSNGWIL
::. . . :: .::.:::.:: .. ..: . : : ... :. : .. .. .
CCDS55 EYVDVVFANRPDPNTPMEETVRAMTHVINQGMAMYWGTSRWSSMEIMEAYSVARQFNLTP
150 160 170 180 190 200
170 180 190 200 210 220
pF1KE6 PTVYQGMYNAITRQ-VETELFPCLRH-FGLRFYAFNPLAGGLLTGKYKYEDKDGKQPVGR
: :. :. . :. ::..: : : : .:. ....::: :...::: .: : .:
CCDS55 PICEQAEYHMFQREKVEVQL-PELFHKIGVGAMTWSPLACGIVSGKYD----SGIPPYSR
210 220 230 240 250 260
230 240 250 260 270
pF1KE6 --FFGNTWAEMYRNRYWKEHHFEGIALVEKALQAA---YGASAPSMTSATLRWMYHHSQL
. : : ... .:. . : . : ::: : . :... : : ..
CCDS55 ASLKGYQW---LKDKILSEEGRRQQAKL-KELQAIAERLGCTLPQLAIA---WCLRN---
270 280 290 300 310
280 290 300 310 320 330
pF1KE6 QGAHGDAVILGMSSLEQLEQNLAAAEEGPLEPAVVDAFNQAWHLVAHECPNYFR
.:. ..:.:: :. .:: .:..: . :
CCDS55 EGV--SSVLLGASNADQLMENIGAIQVLPKLSSSIIHEIDSILGNKPYSKKDYRS
320 330 340 350 360
>>CCDS55571.1 KCNAB2 gene_id:8514|Hs108|chr1 (300 aa)
initn: 222 init1: 109 opt: 263 Z-score: 346.4 bits: 72.3 E(32554): 5.6e-13
Smith-Waterman score: 287; 29.1% identity (57.8% similar) in 282 aa overlap (37-306:11-274)
10 20 30 40 50 60
pF1KE6 RARPATVLGAMEMGRRMDAPTSAAVTRAFLERGHTEIDTAFVYSEGQSETILGGLGLRLG
. : . .::: ::. :..:..::.. . :
CCDS55 MAEQLMTLAYDNGINLFDTAEVYAAGKAEVVLGNIIKKKG
10 20 30 40
70 80 90 100 110 120
pF1KE6 GSDCRVKIDTKAIPLFGNSLKPDSLRFQ-----LETSLKRLQCPRVDLFYLHMPDHSTPV
. : :: : :.. .: . :..::.::: ::. . . :: .::.
CCDS55 WRRSSLVITTK-IFWGGKAETERGLSRKHIIEGLKASLERLQLEYVDVVFANRPDPNTPM
50 60 70 80 90
130 140 150 160 170 180
pF1KE6 EETLRACHQLHQEGKFVELGLSNYAAWEVAEICTLCKSNGWILPTVYQGMYNAITRQ-VE
:::.:: .. ..: . : : ... :. : .. .. . : :. :. . :. ::
CCDS55 EETVRAMTHVINQGMAMYWGTSRWSSMEIMEAYSVARQFNLTPPICEQAEYHMFQREKVE
100 110 120 130 140 150
190 200 210 220 230
pF1KE6 TELFPCLRH-FGLRFYAFNPLAGGLLTGKYKYEDKDGKQPVGR--FFGNTWAEMYRNRYW
..: : : : .:. ....::: :...::: .: : .: . : : ...
CCDS55 VQL-PELFHKIGVGAMTWSPLACGIVSGKYD----SGIPPYSRASLKGYQW---LKDKIL
160 170 180 190 200 210
240 250 260 270 280 290
pF1KE6 KEHHFEGIALVEKALQAA---YGASAPSMTSATLRWMYHHSQLQGAHGDAVILGMSSLEQ
.:. . : . : ::: : . :... : : .. .:. ..:.:: :. .:
CCDS55 SEEGRRQQAKL-KELQAIAERLGCTLPQLAIA---WCLRN---EGV--SSVLLGASNADQ
220 230 240 250 260
300 310 320 330
pF1KE6 LEQNLAAAEEGPLEPAVVDAFNQAWHLVAHECPNYFR
: .:..: . :
CCDS55 LMENIGAIQVLPKLSSSIIHEIDSILGNKPYSKKDYRS
270 280 290 300
>>CCDS33882.1 KCNAB1 gene_id:7881|Hs108|chr3 (401 aa)
initn: 258 init1: 103 opt: 261 Z-score: 341.8 bits: 71.8 E(32554): 1e-12
Smith-Waterman score: 279; 27.5% identity (58.0% similar) in 295 aa overlap (20-306:96-375)
10 20 30 40
pF1KE6 MSRQLSRARPATVLGAMEMGRRMDAPTSAAVTRAFLERGHTEIDTAFVY
:. : . .: :. : : . .::: ::
CCDS33 AKQTGMKYRNLGKSGLRVSCLGLGTWVTFGGQISDEVAERLMTIAY-ESGVNLFDTAEVY
70 80 90 100 110 120
50 60 70 80 90 100
pF1KE6 SEGQSETILGGLGLRLGGSDCRVKIDTKAIPLFGNSLKPDSLRFQ-----LETSLKRLQC
. :..:.:::.. . : . : :: . :.. .: . :. ::.:::
CCDS33 AAGKAEVILGSIIKKKGWRRSSLVITTK-LYWGGKAETERGLSRKHIIEGLKGSLQRLQL
130 140 150 160 170 180
110 120 130 140 150 160
pF1KE6 PRVDLFYLHMPDHSTPVEETLRACHQLHQEGKFVELGLSNYAAWEVAEICTLCKSNGWIL
::. . . :: .::.:: .:: .. ..: . : : ..: :. : .. .. . :
CCDS33 EYVDVVFANRPDSNTPMEEIVRAMTHVINQGMAMYWGTSRWSAMEIMEAYSVARQFNMIP
190 200 210 220 230 240
170 180 190 200 210 220
pF1KE6 PTVYQGMYNAITRQ-VETELFPCLRH-FGLRFYAFNPLAGGLLTGKYKYEDKDGKQPVGR
:. :. :. . :. ::..: : : : .:. ....::: :...::: .... .
CCDS33 PVCEQAEYHLFQREKVEVQL-PELYHKIGVGAMTWSPLACGIISGKYGNGVPESSRASLK
250 260 270 280 290 300
230 240 250 260 270 280
pF1KE6 FFGNTWAEMYRNRYWKEHH-FEGIALVEKALQAAYGASAPSMTSATLRWMYHHSQLQGAH
. .. .. :... .. .. . . : : . :... : : .. .:.
CCDS33 CYQWLKERIVSEEGRKQQNKLKDLSPIAERL----GCTLPQLAVA---WCLRN---EGV-
310 320 330 340 350
290 300 310 320 330
pF1KE6 GDAVILGMSSLEQLEQNLAAAEEGPLEPAVVDAFNQAWHLVAHECPNYFR
..:.:: :. ::: .::.: . :
CCDS33 -SSVLLGSSTPEQLIENLGAIQVLPKMTSHVVNEIDNILRNKPYSKKDYRS
360 370 380 390 400
>>CCDS3175.1 KCNAB1 gene_id:7881|Hs108|chr3 (408 aa)
initn: 258 init1: 103 opt: 261 Z-score: 341.6 bits: 71.8 E(32554): 1e-12
Smith-Waterman score: 279; 27.5% identity (58.0% similar) in 295 aa overlap (20-306:103-382)
10 20 30 40
pF1KE6 MSRQLSRARPATVLGAMEMGRRMDAPTSAAVTRAFLERGHTEIDTAFVY
:. : . .: :. : : . .::: ::
CCDS31 RAETGMAYRNLGKSGLRVSCLGLGTWVTFGGQISDEVAERLMTIAY-ESGVNLFDTAEVY
80 90 100 110 120 130
50 60 70 80 90 100
pF1KE6 SEGQSETILGGLGLRLGGSDCRVKIDTKAIPLFGNSLKPDSLRFQ-----LETSLKRLQC
. :..:.:::.. . : . : :: . :.. .: . :. ::.:::
CCDS31 AAGKAEVILGSIIKKKGWRRSSLVITTK-LYWGGKAETERGLSRKHIIEGLKGSLQRLQL
140 150 160 170 180 190
110 120 130 140 150 160
pF1KE6 PRVDLFYLHMPDHSTPVEETLRACHQLHQEGKFVELGLSNYAAWEVAEICTLCKSNGWIL
::. . . :: .::.:: .:: .. ..: . : : ..: :. : .. .. . :
CCDS31 EYVDVVFANRPDSNTPMEEIVRAMTHVINQGMAMYWGTSRWSAMEIMEAYSVARQFNMIP
200 210 220 230 240 250
170 180 190 200 210 220
pF1KE6 PTVYQGMYNAITRQ-VETELFPCLRH-FGLRFYAFNPLAGGLLTGKYKYEDKDGKQPVGR
:. :. :. . :. ::..: : : : .:. ....::: :...::: .... .
CCDS31 PVCEQAEYHLFQREKVEVQL-PELYHKIGVGAMTWSPLACGIISGKYGNGVPESSRASLK
260 270 280 290 300
230 240 250 260 270 280
pF1KE6 FFGNTWAEMYRNRYWKEHH-FEGIALVEKALQAAYGASAPSMTSATLRWMYHHSQLQGAH
. .. .. :... .. .. . . : : . :... : : .. .:.
CCDS31 CYQWLKERIVSEEGRKQQNKLKDLSPIAERL----GCTLPQLAVA---WCLRN---EGV-
310 320 330 340 350
290 300 310 320 330
pF1KE6 GDAVILGMSSLEQLEQNLAAAEEGPLEPAVVDAFNQAWHLVAHECPNYFR
..:.:: :. ::: .::.: . :
CCDS31 -SSVLLGSSTPEQLIENLGAIQVLPKMTSHVVNEIDNILRNKPYSKKDYRS
360 370 380 390 400
>>CCDS3174.1 KCNAB1 gene_id:7881|Hs108|chr3 (419 aa)
initn: 258 init1: 103 opt: 261 Z-score: 341.5 bits: 71.8 E(32554): 1.1e-12
Smith-Waterman score: 279; 27.5% identity (58.0% similar) in 295 aa overlap (20-306:114-393)
10 20 30 40
pF1KE6 MSRQLSRARPATVLGAMEMGRRMDAPTSAAVTRAFLERGHTEIDTAFVY
:. : . .: :. : : . .::: ::
CCDS31 VCTTGMPHRNLGKSGLRVSCLGLGTWVTFGGQISDEVAERLMTIAY-ESGVNLFDTAEVY
90 100 110 120 130 140
50 60 70 80 90 100
pF1KE6 SEGQSETILGGLGLRLGGSDCRVKIDTKAIPLFGNSLKPDSLRFQ-----LETSLKRLQC
. :..:.:::.. . : . : :: . :.. .: . :. ::.:::
CCDS31 AAGKAEVILGSIIKKKGWRRSSLVITTK-LYWGGKAETERGLSRKHIIEGLKGSLQRLQL
150 160 170 180 190 200
110 120 130 140 150 160
pF1KE6 PRVDLFYLHMPDHSTPVEETLRACHQLHQEGKFVELGLSNYAAWEVAEICTLCKSNGWIL
::. . . :: .::.:: .:: .. ..: . : : ..: :. : .. .. . :
CCDS31 EYVDVVFANRPDSNTPMEEIVRAMTHVINQGMAMYWGTSRWSAMEIMEAYSVARQFNMIP
210 220 230 240 250 260
170 180 190 200 210 220
pF1KE6 PTVYQGMYNAITRQ-VETELFPCLRH-FGLRFYAFNPLAGGLLTGKYKYEDKDGKQPVGR
:. :. :. . :. ::..: : : : .:. ....::: :...::: .... .
CCDS31 PVCEQAEYHLFQREKVEVQL-PELYHKIGVGAMTWSPLACGIISGKYGNGVPESSRASLK
270 280 290 300 310 320
230 240 250 260 270 280
pF1KE6 FFGNTWAEMYRNRYWKEHH-FEGIALVEKALQAAYGASAPSMTSATLRWMYHHSQLQGAH
. .. .. :... .. .. . . : : . :... : : .. .:.
CCDS31 CYQWLKERIVSEEGRKQQNKLKDLSPIAERL----GCTLPQLAVA---WCLRN---EGV-
330 340 350 360
290 300 310 320 330
pF1KE6 GDAVILGMSSLEQLEQNLAAAEEGPLEPAVVDAFNQAWHLVAHECPNYFR
..:.:: :. ::: .::.: . :
CCDS31 -SSVLLGSSTPEQLIENLGAIQVLPKMTSHVVNEIDNILRNKPYSKKDYRS
370 380 390 400 410
331 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Nov 8 12:20:56 2016 done: Tue Nov 8 12:20:57 2016
Total Scan time: 1.830 Total Display time: 0.010
Function used was FASTA [36.3.4 Apr, 2011]