Result of FASTA (ccds) for
pFN21AE6345
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE6345, 369 aa
1>>>pF1KE6345 369 - 369 aa - 369 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.3526+/-0.000916; mu= 15.9855+/- 0.054
mean_var=61.0985+/-12.638, 0's: 0 Z-trim(105.3): 26 B-trim: 122 in 1/48
Lambda= 0.164081
statistics sampled from 8324 (8337) to 8324 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.635), E-opt: 0.2 (0.256), width: 16
Scan time: 2.350
The best scores are: opt bits E(32554)
CCDS10698.1 HSD3B7 gene_id:80270|Hs108|chr16 ( 369) 2511 603.0 1.4e-172
CCDS45466.1 HSD3B7 gene_id:80270|Hs108|chr16 ( 196) 1200 292.5 2e-79
CCDS903.1 HSD3B1 gene_id:3283|Hs108|chr1 ( 373) 846 208.8 6.1e-54
CCDS902.1 HSD3B2 gene_id:3284|Hs108|chr1 ( 372) 820 202.7 4.3e-52
CCDS42205.1 SDR42E1 gene_id:93517|Hs108|chr16 ( 393) 453 115.8 6.4e-26
CCDS14717.1 NSDHL gene_id:50814|Hs108|chrX ( 373) 286 76.3 4.9e-14
>>CCDS10698.1 HSD3B7 gene_id:80270|Hs108|chr16 (369 aa)
initn: 2511 init1: 2511 opt: 2511 Z-score: 3212.1 bits: 603.0 E(32554): 1.4e-172
Smith-Waterman score: 2511; 100.0% identity (100.0% similar) in 369 aa overlap (1-369:1-369)
10 20 30 40 50 60
pF1KE6 MADSAQAQKLVYLVTGGCGFLGEHVVRMLLQREPRLGELRVFDQHLGPWLEELKTGPVRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 MADSAQAQKLVYLVTGGCGFLGEHVVRMLLQREPRLGELRVFDQHLGPWLEELKTGPVRV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 TAIQGDVTQAHEVAAAVAGAHVVIHTAGLVDVFGRASPKTIHEVNVQGTRNVIEACVQTG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 TAIQGDVTQAHEVAAAVAGAHVVIHTAGLVDVFGRASPKTIHEVNVQGTRNVIEACVQTG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 TRFLVYTSSMEVVGPNTKGHPFYRGNEDTPYEAVHRHPYPCSKALAEWLVLEANGRKVRG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 TRFLVYTSSMEVVGPNTKGHPFYRGNEDTPYEAVHRHPYPCSKALAEWLVLEANGRKVRG
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE6 GLPLVTCALRPTGIYGEGHQIMRDFYRQGLRLGGWLFRAIPASVEHGRVYVGNVAWMHVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 GLPLVTCALRPTGIYGEGHQIMRDFYRQGLRLGGWLFRAIPASVEHGRVYVGNVAWMHVL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE6 AARELEQRATLMGGQVYFCYDGSPYRSYEDFNMEFLGPCGLRLVGARPLLPYWLLVFLAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 AARELEQRATLMGGQVYFCYDGSPYRSYEDFNMEFLGPCGLRLVGARPLLPYWLLVFLAA
250 260 270 280 290 300
310 320 330 340 350 360
pF1KE6 LNALLQWLLRPLVLYAPLLNPYTLAVANTTFTVSTDKAQRHFGYEPLFSWEDSRTRTILW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS10 LNALLQWLLRPLVLYAPLLNPYTLAVANTTFTVSTDKAQRHFGYEPLFSWEDSRTRTILW
310 320 330 340 350 360
pF1KE6 VQAATGSAQ
:::::::::
CCDS10 VQAATGSAQ
>>CCDS45466.1 HSD3B7 gene_id:80270|Hs108|chr16 (196 aa)
initn: 1188 init1: 1188 opt: 1200 Z-score: 1539.2 bits: 292.5 E(32554): 2e-79
Smith-Waterman score: 1200; 96.8% identity (97.3% similar) in 187 aa overlap (1-187:1-185)
10 20 30 40 50 60
pF1KE6 MADSAQAQKLVYLVTGGCGFLGEHVVRMLLQREPRLGELRVFDQHLGPWLEELKTGPVRV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 MADSAQAQKLVYLVTGGCGFLGEHVVRMLLQREPRLGELRVFDQHLGPWLEELKTGPVRV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 TAIQGDVTQAHEVAAAVAGAHVVIHTAGLVDVFGRASPKTIHEVNVQGTRNVIEACVQTG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS45 TAIQGDVTQAHEVAAAVAGAHVVIHTAGLVDVFGRASPKTIHEVNVQGTRNVIEACVQTG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 TRFLVYTSSMEVVGPNTKGHPFYRGNEDTPYEAVHRHPYPCSKALAEWLVLEANGRKVRG
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::.
CCDS45 TRFLVYTSSMEVVGPNTKGHPFYRGNEDTPYEAVHRHPYPCSKALAEWLVLEANGRKAM-
130 140 150 160 170
190 200 210 220 230 240
pF1KE6 GLPLVTCALRPTGIYGEGHQIMRDFYRQGLRLGGWLFRAIPASVEHGRVYVGNVAWMHVL
:: ::
CCDS45 -LPGCTCWQPGSWSSGQP
180 190
>>CCDS903.1 HSD3B1 gene_id:3283|Hs108|chr1 (373 aa)
initn: 643 init1: 519 opt: 846 Z-score: 1081.9 bits: 208.8 E(32554): 6.1e-54
Smith-Waterman score: 846; 39.5% identity (69.8% similar) in 354 aa overlap (13-361:7-357)
10 20 30 40 50
pF1KE6 MADSAQAQKLVYLVTGGCGFLGEHVVRMLLQREPRLGELRVFDQHLGPWL-EELKT--GP
::::. ::::....:.:. .: .: :.::.:. .:: : ::.. .
CCDS90 MTGWSCLVTGAGGFLGQRIIRLLV-KEKELKEIRVLDKAFGPELREEFSKLQNK
10 20 30 40 50
60 70 80 90 100 110
pF1KE6 VRVTAIQGDVTQAHEVAAAVAGAHVVIHTAGLVDVFGRASPKTIHEVNVQGTRNVIEACV
...:...::. . . : . :.:::: ..:::: . ..: .:::.::. ..::::
CCDS90 TKLTVLEGDILDEPFLKRACQDVSVIIHTACIIDVFGVTHRESIMNVNVKGTQLLLEACV
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE6 QTGTRFLVYTSSMEVVGPNTKGHPFYRGNEDTPYEAVHRHPYPCSKALAEWLVLEANGRK
:... ..::::.::.:::. . . :.:. : : . ::: :: ::: :: ::: .
CCDS90 QASVPVFIYTSSIEVAGPNSYKEIIQNGHEEEPLENTWPAPYPHSKKLAEKAVLAANGWN
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE6 VRGGLPLVTCALRPTGIYGEGHQIMRDFYRQGLRLGGWLFRAIPASVEHGRVYVGNVAWM
...: : :::::: ::::: ... ..: .: .. .. . ::::::::
CCDS90 LKNGGTLYTCALRPMYIYGEGSRFLSASINEALNNNG-ILSSVGKFSTVNPVYVGNVAWA
180 190 200 210 220 230
240 250 260 270 280 290
pF1KE6 HVLAARELE--QRATLMGGQVYFCYDGSPYRSYEDFNMEFLGPCGLRLVGARPLLPYWLL
:.:: : :. ..: . :: :. : .:..::...:. . :::: .: .: :.
CCDS90 HILALRALQDPKKAPSIRGQFYYISDDTPHQSYDNLNYTLSKEFGLRL-DSRWSFPLSLM
240 250 260 270 280 290
300 310 320 330 340 350
pF1KE6 VFLAALNALLQWLLRPLVLYAPLLNPYTLAVANTTFTVSTDKAQRHFGYEPLFSWEDSRT
... : ....::::. : : .: . ....:..:: : :::: ..:.::.:::...
CCDS90 YWIGFLLEIVSFLLRPIYTYRPPFNRHIVTLSNSVFTFSYKKAQRDLAYKPLYSWEEAKQ
300 310 320 330 340 350
360
pF1KE6 RTILWVQAATGSAQ
.:. ::
CCDS90 KTVEWVGSLVDRHKETLKSKTQ
360 370
>>CCDS902.1 HSD3B2 gene_id:3284|Hs108|chr1 (372 aa)
initn: 583 init1: 525 opt: 820 Z-score: 1048.7 bits: 202.7 E(32554): 4.3e-52
Smith-Waterman score: 820; 39.8% identity (69.5% similar) in 354 aa overlap (13-361:6-356)
10 20 30 40 50
pF1KE6 MADSAQAQKLVYLVTGGCGFLGEHVVRMLLQREPRLGELRVFDQHLGPWL-EELKT--GP
::::. :.::...::.:.. : .: :.:..:. . : : ::.. .
CCDS90 MGWSCLVTGAGGLLGQRIVRLLVE-EKELKEIRALDKAFRPELREEFSKLQNR
10 20 30 40 50
60 70 80 90 100 110
pF1KE6 VRVTAIQGDVTQAHEVAAAVAGAHVVIHTAGLVDVFGRASPKTIHEVNVQGTRNVIEACV
...:...::. . . : . :::::: ..:::: . ..: .:::.::. ..::::
CCDS90 TKLTVLEGDILDEPFLKRACQDVSVVIHTACIIDVFGVTHRESIMNVNVKGTQLLLEACV
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE6 QTGTRFLVYTSSMEVVGPNTKGHPFYRGNEDTPYEAVHRHPYPCSKALAEWLVLEANGRK
:... ..::::.::.:::. . . :.:. : : . ::: :: ::: :: ::: .
CCDS90 QASVPVFIYTSSIEVAGPNSYKEIIQNGHEEEPLENTWPTPYPYSKKLAEKAVLAANGWN
120 130 140 150 160 170
180 190 200 210 220 230
pF1KE6 VRGGLPLVTCALRPTGIYGEGHQIMRDFYRQGLRLGGWLFRAIPASVEHGRVYVGNVAWM
...: : ::::::: ::::: .. ..: .: .. .. . ::::::::
CCDS90 LKNGDTLYTCALRPTYIYGEGGPFLSASINEALNNNG-ILSSVGKFSTVNPVYVGNVAWA
180 190 200 210 220 230
240 250 260 270 280 290
pF1KE6 HVLAARELE--QRATLMGGQVYFCYDGSPYRSYEDFNMEFLGPCGLRLVGARPLLPYWLL
:.:: : :. ..: . :: :. : .:..::...:. . :::: .: :: :.
CCDS90 HILALRALRDPKKAPSVRGQFYYISDDTPHQSYDNLNYILSKEFGLRL-DSRWSLPLTLM
240 250 260 270 280 290
300 310 320 330 340 350
pF1KE6 VFLAALNALLQWLLRPLVLYAPLLNPYTLAVANTTFTVSTDKAQRHFGYEPLFSWEDSRT
... : ....:: :. : : .: .:....:..:: : :::: ..:.::.:::...
CCDS90 YWIGFLLEVVSFLLSPIYSYQPPFNRHTVTLSNSVFTFSYKKAQRDLAYKPLYSWEEAKQ
300 310 320 330 340 350
360
pF1KE6 RTILWVQAATGSAQ
.:. ::
CCDS90 KTVEWVGSLVDRHKETLKSKTQ
360 370
>>CCDS42205.1 SDR42E1 gene_id:93517|Hs108|chr16 (393 aa)
initn: 240 init1: 148 opt: 453 Z-score: 578.8 bits: 115.8 E(32554): 6.4e-26
Smith-Waterman score: 453; 33.2% identity (57.7% similar) in 355 aa overlap (3-345:2-337)
10 20 30 40 50 60
pF1KE6 MADSAQAQKLVYLVTGGCGFLGEHVVRMLLQREPRLGELRVFDQHLGPWLEELKTGPVRV
: ..:: :.::: :..: .. : : . . .:: .: .: : .
CCDS42 MDPKRSQKESVLITGGSGYFGFRLGCALNQNGVH---VILFDIS-SP----AQTIPEGI
10 20 30 40 50
70 80 90 100 110
pF1KE6 TAIQGDVTQAHEVAAAVAGAHV--VIHTAGLVDVFGRA--SPKTIHEVNVQGTRNVIEAC
::::. . .: : : : :.: :. . :: . . :.::::.:: :....:
CCDS42 KFIQGDIRHLSDVEKAFQDADVTCVFHIASY-GMSGREQLNRNLIKEVNVRGTDNILQVC
60 70 80 90 100 110
120 130 140 150 160 170
pF1KE6 VQTGTRFLVYTSSMEVVGPNTKGHPFYRGNEDTPYEAVHRHP--YPCSKALAEWLVLEAN
. . :::::...:. :. . :.:. :: .: :: : .:..:: :::::
CCDS42 QRRRVPRLVYTSTFNVI---FGGQVIRNGDESLPYLPLHLHPDHYSRTKSIAEQKVLEAN
120 130 140 150 160
180 190 200 210 220
pF1KE6 GRKV-RGGLPLVTCALRPTGIYGEGHQIMRDFYRQGLRLGGWLFRAI---PAS-VEHGRV
. . :: : ::::::.:::: :.: : . : . ::. . : : :: :
CCDS42 ATPLDRGDGVLRTCALRPAGIYGPGEQ--RHLPRIVSYIEKGLFKFVYGDPRSLVEF--V
170 180 190 200 210 220
230 240 250 260 270 280
pF1KE6 YVGNVAWMHVLAARELE-QRATLMGGQVYFCYDGSPYRSYEDFNMEFLGPCGLRLVGARP
.: :.. :.::.. :. ... . .:: :: :: : ..: : : : . ..:
CCDS42 HVDNLVQAHILASEALRADKGHIASGQPYFISDGRPVNNFEFFRPLVEG-LGYTFPSTR-
230 240 250 260 270 280
290 300 310 320 330 340
pF1KE6 LLPYWLLVFLAALNALLQWLLRPLVLYAPLLNPYTLAVANTTFTVSTDKAQRHFGYEPLF
:: :. .: :. .....: : . :.:. . ...: : .::....::.
CCDS42 -LPLTLVYCFAFLTEMVHFILGRLYNFQPFLTRTEVYKTGVTHYFSLEKAKKELGYKAQP
290 300 310 320 330 340
350 360
pF1KE6 SWEDSRTRTILWVQAATGSAQ
CCDS42 FDLQEAVEWFKAHGHGRSSGSRDSECFVWDGLLVFLLIIAVLMWLPSSVILSL
350 360 370 380 390
>>CCDS14717.1 NSDHL gene_id:50814|Hs108|chrX (373 aa)
initn: 427 init1: 174 opt: 286 Z-score: 365.5 bits: 76.3 E(32554): 4.9e-14
Smith-Waterman score: 446; 29.9% identity (55.6% similar) in 354 aa overlap (6-358:34-363)
10 20 30
pF1KE6 MADSAQAQKLVYLVTGGCGFLGEHVVRMLLQREPR
: : : :: ::::.:.:..:: :
CCDS14 AVSEPMRDQVARTHLTEDTPKVNADIEKVNQNQAKRCTVIGGSGFLGQHMVEQLLAR---
10 20 30 40 50 60
40 50 60 70 80 90
pF1KE6 LG-ELRVFDQHLGPWLEELKTGPVRVTAIQGDVTQAHEVAAAVAGAHVVIHTAGLVDVFG
: . ::: . : . . :: . ::. . ... :. :...:.: :. .
CCDS14 -GYAVNVFDIQQG-----FDNPQVRF--FLGDLCSRQDLYPALKGVNTVFHCAS--PPPS
70 80 90 100 110
100 110 120 130 140 150
pF1KE6 RASPKTIHEVNVQGTRNVIEACVQTGTRFLVYTSSMEVVGPNTKGHPFYRGNEDTPYEAV
. . ...:: ::.::::.: ..:.. :. ::: :. .: . :.:: ::
CCDS14 SNNKELFYRVNYIGTKNVIETCKEAGVQKLILTSSASVI---FEGVDIKNGTEDLPYAMK
120 130 140 150 160
160 170 180 190 200 210
pF1KE6 HRHPYPCSKALAEWLVLEANGRKVRGGLPLVTCALRPTGIYGEGHQIMRDFYRQGLRLGG
: .: : : :: :: . ..: :.:: ::.: . . .. : :
CCDS14 PIDYYTETKILQERAVLGANDPEKN----FLTTAIRPHGIFGPRDPQLVPILIEAARNGK
170 180 190 200 210 220
220 230 240 250 260 270
pF1KE6 WLFRAIPASVEHGRVYVGNVAWMHVLAARELEQRATLMGGQVYFCYDGSPYRSYEDFNME
: .. ..: ::. :.:::..: .: . .::... . : . : .
CCDS14 MKFVIGNGKNLVDFTFVENVVHGHILAAEQL-SRDSTLGGKAFHITNDEPI-PFWTFLSR
230 240 250 260 270 280
280 290 300 310 320 330
pF1KE6 FLGPCGLRLVGARPLLPYWLLVFLAALNALLQWLLRPLVLYAPLLNPYTLAVANTTFTVS
.: :: . . .:::. .:: : .:: .. :.. : ..:. .:.:.: :
CCDS14 IL--TGLNYEAPKYHIPYWVAYYLALLLSLLVMVISPVIQLQPTFTPMRVALAGTFHYYS
290 300 310 320 330
340 350 360
pF1KE6 TDKAQRHFGYEPLFSWEDSRTRTILWVQAATGSAQ
..:.. .::.:: . .:. ::.
CCDS14 CERAKKAMGYQPLVTMDDAMERTVQSFRHLRRVK
340 350 360 370
369 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Nov 8 12:19:02 2016 done: Tue Nov 8 12:19:02 2016
Total Scan time: 2.350 Total Display time: 0.010
Function used was FASTA [36.3.4 Apr, 2011]