Result of FASTA (omim) for
pFN21AE6344
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KE6344, 355 aa
1>>>pF1KE6344 355 - 355 aa - 355 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 4.9075+/-0.000396; mu= 18.7951+/- 0.025
mean_var=67.6854+/-13.507, 0's: 0 Z-trim(111.5): 17 B-trim: 0 in 0/56
Lambda= 0.155893
statistics sampled from 20120 (20133) to 20120 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.609), E-opt: 0.2 (0.236), width: 16
Scan time: 5.790
The best scores are: opt bits E(85289)
NP_004535 (OMIM: 256000,603835) NADH dehydrogenase ( 355) 2387 546.0 4.7e-155
NP_001308948 (OMIM: 256000,603835) NADH dehydrogen ( 375) 2226 509.8 3.9e-144
XP_011509530 (OMIM: 256000,603835) PREDICTED: NADH ( 362) 2222 508.9 7e-144
NP_001308949 (OMIM: 256000,603835) NADH dehydrogen ( 317) 1985 455.6 7e-128
NP_550438 (OMIM: 251880,601465,617068,617070) deox ( 277) 150 42.8 0.0011
>>NP_004535 (OMIM: 256000,603835) NADH dehydrogenase [ub (355 aa)
initn: 2387 init1: 2387 opt: 2387 Z-score: 2904.8 bits: 546.0 E(85289): 4.7e-155
Smith-Waterman score: 2387; 100.0% identity (100.0% similar) in 355 aa overlap (1-355:1-355)
10 20 30 40 50 60
pF1KE6 MALRLLKLAATSASARVVAAGAQRVRGIHSSVQCKLRYGMWHFLLGDKASKRLTERSRVI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 MALRLLKLAATSASARVVAAGAQRVRGIHSSVQCKLRYGMWHFLLGDKASKRLTERSRVI
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 TVDGNICTGKGKLAKEIAEKLGFKHFPEAGIHYPDSTTGDGKPLATDYNGNCSLEKFYDD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 TVDGNICTGKGKLAKEIAEKLGFKHFPEAGIHYPDSTTGDGKPLATDYNGNCSLEKFYDD
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 PRSNDGNSYRLQSWLYSSRLLQYSDALEHLLTTGQGVVLERSIFSDFVFLEAMYNQGFIR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 PRSNDGNSYRLQSWLYSSRLLQYSDALEHLLTTGQGVVLERSIFSDFVFLEAMYNQGFIR
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE6 KQCVDHYNEVKSVTICDYLPPHLVIYIDVPVPEVQRRIQKKGDPHEMKITSAYLQDIENA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 KQCVDHYNEVKSVTICDYLPPHLVIYIDVPVPEVQRRIQKKGDPHEMKITSAYLQDIENA
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE6 YKKTFLPEMSEKCEVLQYSAREAQDSKKVVEDIEYLKFDKGPWLKQDNRTLYHLRLLVQD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 YKKTFLPEMSEKCEVLQYSAREAQDSKKVVEDIEYLKFDKGPWLKQDNRTLYHLRLLVQD
250 260 270 280 290 300
310 320 330 340 350
pF1KE6 KFEVLNYTSIPIFLPEVTIGAHQTDRVLHQFRELPGRKYSPGYNTEVGDKWIWLK
:::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_004 KFEVLNYTSIPIFLPEVTIGAHQTDRVLHQFRELPGRKYSPGYNTEVGDKWIWLK
310 320 330 340 350
>>NP_001308948 (OMIM: 256000,603835) NADH dehydrogenase (375 aa)
initn: 2222 init1: 2222 opt: 2226 Z-score: 2708.7 bits: 509.8 E(85289): 3.9e-144
Smith-Waterman score: 2226; 98.5% identity (98.8% similar) in 341 aa overlap (1-338:1-341)
10 20 30 40 50 60
pF1KE6 MALRLLKLAATSASARVVAAGAQRVRGIHSSVQCKLRYGMWHFLLGDKASKRLTERSRVI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MALRLLKLAATSASARVVAAGAQRVRGIHSSVQCKLRYGMWHFLLGDKASKRLTERSRVI
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 TVDGNICTGKGKLAKEIAEKLGFKHFPEAGIHYPDSTTGDGKPLATDYNGNCSLEKFYDD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TVDGNICTGKGKLAKEIAEKLGFKHFPEAGIHYPDSTTGDGKPLATDYNGNCSLEKFYDD
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 PRSNDGNSYRLQSWLYSSRLLQYSDALEHLLTTGQGVVLERSIFSDFVFLEAMYNQGFIR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PRSNDGNSYRLQSWLYSSRLLQYSDALEHLLTTGQGVVLERSIFSDFVFLEAMYNQGFIR
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE6 KQCVDHYNEVKSVTICDYLPPHLVIYIDVPVPEVQRRIQKKGDPHEMKITSAYLQDIENA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KQCVDHYNEVKSVTICDYLPPHLVIYIDVPVPEVQRRIQKKGDPHEMKITSAYLQDIENA
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE6 YKKTFLPEMSEKCEVLQYSAREAQDSKKVVEDIEYLKFDKGPWLKQDNRTLYHLRLLVQD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YKKTFLPEMSEKCEVLQYSAREAQDSKKVVEDIEYLKFDKGPWLKQDNRTLYHLRLLVQD
250 260 270 280 290 300
310 320 330 340 350
pF1KE6 KFEVLNYTSIPIFLPEVTIGAHQTDRVLHQFRELP---GRKYSPGYNTEVGDKWIWLK
:::::::::::::::::::::::::::::::::. :::
NP_001 KFEVLNYTSIPIFLPEVTIGAHQTDRVLHQFREFSLFNGRKPDAVKILCSLLEADRSLLE
310 320 330 340 350 360
NP_001 ADRSLLEADRVQDSC
370
>>XP_011509530 (OMIM: 256000,603835) PREDICTED: NADH deh (362 aa)
initn: 2222 init1: 2222 opt: 2222 Z-score: 2704.1 bits: 508.9 E(85289): 7e-144
Smith-Waterman score: 2222; 99.7% identity (100.0% similar) in 334 aa overlap (1-334:1-334)
10 20 30 40 50 60
pF1KE6 MALRLLKLAATSASARVVAAGAQRVRGIHSSVQCKLRYGMWHFLLGDKASKRLTERSRVI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 MALRLLKLAATSASARVVAAGAQRVRGIHSSVQCKLRYGMWHFLLGDKASKRLTERSRVI
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 TVDGNICTGKGKLAKEIAEKLGFKHFPEAGIHYPDSTTGDGKPLATDYNGNCSLEKFYDD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 TVDGNICTGKGKLAKEIAEKLGFKHFPEAGIHYPDSTTGDGKPLATDYNGNCSLEKFYDD
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 PRSNDGNSYRLQSWLYSSRLLQYSDALEHLLTTGQGVVLERSIFSDFVFLEAMYNQGFIR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PRSNDGNSYRLQSWLYSSRLLQYSDALEHLLTTGQGVVLERSIFSDFVFLEAMYNQGFIR
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE6 KQCVDHYNEVKSVTICDYLPPHLVIYIDVPVPEVQRRIQKKGDPHEMKITSAYLQDIENA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 KQCVDHYNEVKSVTICDYLPPHLVIYIDVPVPEVQRRIQKKGDPHEMKITSAYLQDIENA
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE6 YKKTFLPEMSEKCEVLQYSAREAQDSKKVVEDIEYLKFDKGPWLKQDNRTLYHLRLLVQD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 YKKTFLPEMSEKCEVLQYSAREAQDSKKVVEDIEYLKFDKGPWLKQDNRTLYHLRLLVQD
250 260 270 280 290 300
310 320 330 340 350
pF1KE6 KFEVLNYTSIPIFLPEVTIGAHQTDRVLHQFRELPGRKYSPGYNTEVGDKWIWLK
:::::::::::::::::::::::::::::::::.
XP_011 KFEVLNYTSIPIFLPEVTIGAHQTDRVLHQFREVFQESEAKRLDVEEVCWKKTPLKDRGE
310 320 330 340 350 360
XP_011 EV
>>NP_001308949 (OMIM: 256000,603835) NADH dehydrogenase (317 aa)
initn: 1984 init1: 1984 opt: 1985 Z-score: 2416.8 bits: 455.6 E(85289): 7e-128
Smith-Waterman score: 1985; 97.1% identity (98.1% similar) in 308 aa overlap (1-308:1-308)
10 20 30 40 50 60
pF1KE6 MALRLLKLAATSASARVVAAGAQRVRGIHSSVQCKLRYGMWHFLLGDKASKRLTERSRVI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MALRLLKLAATSASARVVAAGAQRVRGIHSSVQCKLRYGMWHFLLGDKASKRLTERSRVI
10 20 30 40 50 60
70 80 90 100 110 120
pF1KE6 TVDGNICTGKGKLAKEIAEKLGFKHFPEAGIHYPDSTTGDGKPLATDYNGNCSLEKFYDD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TVDGNICTGKGKLAKEIAEKLGFKHFPEAGIHYPDSTTGDGKPLATDYNGNCSLEKFYDD
70 80 90 100 110 120
130 140 150 160 170 180
pF1KE6 PRSNDGNSYRLQSWLYSSRLLQYSDALEHLLTTGQGVVLERSIFSDFVFLEAMYNQGFIR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PRSNDGNSYRLQSWLYSSRLLQYSDALEHLLTTGQGVVLERSIFSDFVFLEAMYNQGFIR
130 140 150 160 170 180
190 200 210 220 230 240
pF1KE6 KQCVDHYNEVKSVTICDYLPPHLVIYIDVPVPEVQRRIQKKGDPHEMKITSAYLQDIENA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 KQCVDHYNEVKSVTICDYLPPHLVIYIDVPVPEVQRRIQKKGDPHEMKITSAYLQDIENA
190 200 210 220 230 240
250 260 270 280 290 300
pF1KE6 YKKTFLPEMSEKCEVLQYSAREAQDSKKVVEDIEYLKFDKGPWLKQDNRTLYHLRLLVQD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::: .
NP_001 YKKTFLPEMSEKCEVLQYSAREAQDSKKVVEDIEYLKFDKGPWLKQDNRTLYHLRLLCRA
250 260 270 280 290 300
310 320 330 340 350
pF1KE6 KFEVLNYTSIPIFLPEVTIGAHQTDRVLHQFRELPGRKYSPGYNTEVGDKWIWLK
.:. :
NP_001 ASTALGTTPRWETSGSG
310
>>NP_550438 (OMIM: 251880,601465,617068,617070) deoxygua (277 aa)
initn: 93 init1: 44 opt: 150 Z-score: 187.2 bits: 42.8 E(85289): 0.0011
Smith-Waterman score: 150; 23.7% identity (57.7% similar) in 194 aa overlap (58-242:39-227)
30 40 50 60 70 80
pF1KE6 IHSSVQCKLRYGMWHFLLGDKASKRLTERSRVITVDGNICTGKGKLAKEIAEKLGFKHFP
: ....::: .::. ..: ... :
NP_550 SRLRAPFSSMAKSPLEGVSSSRGLHAGRGPRRLSIEGNIAVGKSTFVKLLTKTYPEWHVA
10 20 30 40 50 60
90 100 110 120 130 140
pF1KE6 EAGIHYPDS--TTGDGKPLATDYNGNCSLEKFYDDPRSNDGNSYRLQSWLYSSRL-LQYS
. .. ..: : ... :: :. .: .: :: .:.. . ::: .:
NP_550 TEPVATWQNIQAAGTQKACTAQSLGNL-LDMMYREPAR---WSYTFQTFSFLSRLKVQLE
70 80 90 100 110 120
150 160 170 180 190
pF1KE6 DALEHLLTTGQGV-VLERSIFSD-FVFLEAMYNQGFIRKQCVDHYNEVKSVTICDY---L
:.:: . . : ..:::..:: ..: . ....: . :.. .: . .. .
NP_550 PFPEKLLQARKPVQIFERSVYSDRYIFAKNLFENGSLSDIEWHIYQDWHSFLLWEFASRI
130 140 150 160 170 180
200 210 220 230 240 250
pF1KE6 PPHLVIYIDVPVPEV-QRRIQKKGDPHEMKITSAYLQDIENAYKKTFLPEMSEKCEVLQY
: ::... :.: .:. ... .: : :::..... ..
NP_550 TLHGFIYLQAS-PQVCLKRLYQRAREEEKGIELAYLEQLHGQHEAWLIHKTTKLHFEALM
190 200 210 220 230 240
260 270 280 290 300 310
pF1KE6 SAREAQDSKKVVEDIEYLKFDKGPWLKQDNRTLYHLRLLVQDKFEVLNYTSIPIFLPEVT
NP_550 NIPVLVLDVNDDFSEEVTKQEDLMREVNTFVKNL
250 260 270
355 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Tue Nov 8 12:18:24 2016 done: Tue Nov 8 12:18:25 2016
Total Scan time: 5.790 Total Display time: -0.010
Function used was FASTA [36.3.4 Apr, 2011]